Research output per year
Research output per year
Personal profile
Research interests
Clinical interest is in identifying the underlying pathogenesis of necrotizing enterocolitis (NEC) in infants, specifically, evaluating the role of epidermal growth factor (EGF) in NEC prevention. We are studying EGF metabolism using stable isotope infusions and mass spectrometry analysis to identify phenotypic variation in EGF expression. This phenotype will be correlated with results from studies of EGF/EGF receptor genotypes in a population of preterm infants, and ultimately to risk of NEC. We are also evaluating the preterm infant’s intestinal microbial and inflammatory environment, and its contribution to NEC development. Ultimately we would evaluate the impact of exogenous EGF administration to the intestinal milieu. Our work translates basic science research on epidermal growth factor (EGF) to clinical application in preterm infants, ultimately to be used as the basis for clinical trials to prevent NEC.
Clinical interests
Neonatology, Fetal Care
Keywords
- COVID-19
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Collaborations and top research areas from the last five years
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Disentangling Socioeconomic Status and Race in Infant Brain, Birth Weight, and Gestational Age at Birth: A Neural Network Analysis
Sarullo, K., Barch, D. M., Smyser, C. D., Rogers, C., Warner, B. B., Miller, J. P., England, S. K., Luby, J. & Swamidass, S. J., 2023, (Accepted/In press) In: Biological Psychiatry Global Open Science.Research output: Contribution to journal › Article › peer-review
Open Access -
Evaluation of Birth by Cesarean Delivery and Development of Early-Onset Colorectal Cancer
Cao, Y., Nguyen, L. H., Tica, S., Otegbeye, E., Zong, X., Roelstraete, B., Chan, A. T., Warner, B. B., Stephansson, O. & Ludvigsson, J. F., Apr 27 2023, In: JAMA Network Open. 6, 4, p. E2310316Research output: Contribution to journal › Article › peer-review
Open Access -
Gut pathogen colonization precedes bloodstream infection in the neonatal intensive care unit
Schwartz, D. J., Shalon, N., Wardenburg, K., DeVeaux, A., Wallace, M. A., Hall-Moore, C., Ndao, I. M., Sullivan, J. E., Radmacher, P., Escobedo, M., Burnham, C. A. D., Warner, B. B., Tarr, P. I. & Dantas, G., 2023, In: Science translational medicine. 15, 694, eadg5562.Research output: Contribution to journal › Article › peer-review
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Maturation of large-scale brain systems over the first month of life
Nielsen, A. N., Kaplan, S., Meyer, D., Alexopoulos, D., Kenley, J. K., Smyser, T. A., Wakschlag, L. S., Norton, E. S., Raghuraman, N., Warner, B. B., Shimony, J. S., Luby, J. L., Neil, J. J., Petersen, S. E., Barch, D. M., Rogers, C. E., Sylvester, C. M. & Smyser, C. D., Mar 15 2023, In: Cerebral Cortex. 33, 6, p. 2788-2803 16 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Network-specific selectivity of functional connections in the neonatal brain
Sylvester, C. M., Kaplan, S., Myers, M. J., Gordon, E. M., Schwarzlose, R. F., Alexopoulos, D., Nielsen, A. N., Kenley, J. K., Meyer, D., Yu, Q., Graham, A. M., Fair, D. A., Warner, B. B., Barch, D. M., Rogers, C. E., Luby, J. L., Petersen, S. E. & Smyser, C. D., Mar 1 2023, In: Cerebral Cortex. 33, 5, p. 2200-2214 15 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations