Research Output per year
Research Output per year
Personal profile
Research interests
My group is evaluating the role of autophagy and cell death in cytokine responses in pre-clinical models of sepsis.
Areas of Clinical Interest
Immunocompromised hosts, viral infections, emerging infections
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Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output
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A Cytokine Circus with a Viral Ringleader: SARS-CoV-2-Associated Cytokine Storm Syndromes
Cabler, S. S., French, A. R. & Orvedahl, A., Dec 2020, In: Trends in Molecular Medicine. 26, 12, p. 1078-1085 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity
Brestoff, J. R., Wilen, C. B., Moley, J. R., Li, Y., Zou, W., Malvin, N. P., Rowen, M. N., Saunders, B. T., Ma, H., Mack, M. R., Hykes, B. L., Balce, D. R., Orvedahl, A., Williams, J. W., Rohatgi, N., Wang, X., McAllaster, M. R., Handley, S. A., Kim, B. S., Doench, J. G. & 5 others, , 2020, (Accepted/In press) In: Cell metabolism.Research output: Contribution to journal › Article › peer-review
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Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes
Wang, Y. T., Zaitsev, K., Lu, Q., Li, S., Schaiff, W. T., Kim, K. W., Droit, L., Wilen, C. B., Desai, C., Balce, D. R., Orchard, R. C., Orvedahl, A., Park, S., Kreamalmeyer, D., Handley, S. A., Pfeifer, J. D., Baldridge, M. T., Artyomov, M. N., Stallings, C. L. & Virgin, H. W., Feb 1 2020, In: Nature microbiology. 5, 2, p. 272-281 10 p.Research output: Contribution to journal › Letter › peer-review
4 Scopus citations -
Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock
Orvedahl, A., McAllaster, M. R., Sansone, A., Dunlap, B. F., Desai, C., Wang, Y. T., Balce, D. R., Luke, C. J., Lee, S., Orchard, R. C., Artyomov, M. N., Handley, S. A., Doench, J. G., Silverman, G. A. & Virgin, H. W., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 33, p. 16497-16506 10 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Viral complementation of immunodeficiency confers protection against enteric pathogens via interferon-λ
Ingle, H., Lee, S., Ai, T., Orvedahl, A., Rodgers, R., Zhao, G., Sullender, M., Peterson, S. T., Locke, M., Liu, T. C., Yokoyama, C. C., Sharp, B., Schultz-Cherry, S., Miner, J. J. & Baldridge, M. T., Jul 1 2019, In: Nature microbiology. 4, 7, p. 1120-1128 9 p.Research output: Contribution to journal › Letter › peer-review
21 Scopus citations