Research output per year
Research output per year
- 1 - 50 out of 55 results
Search results
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2024
Human PLCG2 haploinsufficiency results in a novel natural killer cell immunodeficiency
Alinger, J. B., Mace, E. M., Porter, J. R., Mah-Som, A. Y., Daugherty, A. L., Li, S., Throm, A. A., Pingel, J. T., Saucier, N., Yao, A., Chinn, I. K., Lupski, J. R., Ehlayel, M., Keller, M., Bowman, G. R., Cooper, M. A., Orange, J. S. & French, A. R., Jan 2024, In: Journal of Allergy and Clinical Immunology. 153, 1, p. 216-229 14 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
National Pediatrician-Scientist Collaborative Workgroup comment on new ACGME requirements’ impact on pediatric physician-scientists
for the NPSCW, Moore, D. J., Powell, W., Boyer, D., Bline, K., Harshman, L., Nowalk, A., Burns, A., Orange, J. S., Moore, D. J., Burns, A., Calkins, K. L., Mohr, E., Binstadt, B., Olson, D., Callaway, D., Harris, K., Lajiness, J. D., Heyman, M. & Iness, A. N. & 28 others, , Jan 2024, In: Pediatric research. 95, 1, p. 70-74 5 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
2022
Expansion of a novel population of NK cells with low ribosome expression in juvenile dermatomyositis
Hilliard, K. A., Throm, A. A., Pingel, J. T., Saucier, N., Zaher, H. S. & French, A. R., Oct 31 2022, In: Frontiers in immunology. 13, 1007022.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
2021
Favorable outcomes with reduced steroid use in juvenile dermatomyositis
Orandi, A. B., Fotis, L., Lai, J., Morris, H., White, A. J., French, A. R. & Baszis, K. W., Dec 2021, In: Pediatric Rheumatology. 19, 1, 127.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Reliance on Cox10 and oxidative metabolism for antigen-specific NK cell expansion
Mah-Som, A. Y., Keppel, M. P., Tobin, J. M., Kolicheski, A., Saucier, N., Sexl, V., French, A. R., Wagner, J. A., Fehniger, T. A. & Cooper, M. A., Jun 1 2021, In: Cell Reports. 35, 9, 109209.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2019
MicroRNA-142 Is Critical for the Homeostasis and Function of Type 1 Innate Lymphoid Cells
Berrien-Elliott, M. M., Sun, Y., Neal, C., Ireland, A., Trissal, M. C., Sullivan, R. P., Wagner, J. A., Leong, J. W., Wong, P., Mah-Som, A. Y., Wong, T. N., Schappe, T., Keppel, C. R., Cortez, V. S., Stamatiades, E. G., Li, M. O., Colonna, M., Link, D. C., French, A. R. & Cooper, M. A. & 4 others, , Sep 17 2019, In: Immunity. 51, 3, p. 479-490.e6Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
2018
Dysregulated NK cell PLCγ2 signaling and activity in juvenile dermatomyositis
Throm, A. A., Alinger, J. B., Pingel, J. T., Daugherty, A. L., Pachman, L. M. & French, A. R., Nov 15 2018, In: JCI Insight. 3, 22Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Epidemiology and Outcomes of Granulomatosis With Polyangiitis in Pediatric and Working-Age Adult Populations In the United States: Analysis of a Large National Claims Database
Panupattanapong, S., Stwalley, D. L., White, A. J., Olsen, M. A., French, A. R. & Hartman, M. E., Dec 2018, In: Arthritis and Rheumatology. 70, 12, p. 2067-2076 10 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
Identification of enhanced IFN-γ signaling in polyarticular juvenile idiopathic arthritis with mass cytometry
Throm, A. A., Moncrieffe, H., Orandi, A. B., Pingel, J. T., Geurs, T. L., Miller, H. L., Daugherty, A. L., Malkova, O. N., Lovell, D. J., Thompson, S. D., Grom, A. A., Cooper, M. A., Oh, S. T. & French, A. R., Aug 9 2018, In: JCI Insight. 3, 15Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
2017
Glycolytic requirement for NK cell cytotoxicity and cytomegalovirus control
Mah, A. Y., Rashidi, A., Keppel, M. P., Saucier, N., Moore, E. K., Alinger, J. B., Tripathy, S., Agarwal, S. K., Jeng, E. K., Wong, H. C., Miller, J. S., Fehniger, T. A., Mace, E. M., French, A. & Cooper, M., Dec 7 2017, In: JCI Insight. 2, 23, e95128.Research output: Contribution to journal › Article › peer-review
Open Access97 Scopus citations -
Proteomic and phylogenetic coevolution analyses of pM79 and pM92 identify interactions with RNA polymerase II and delineate the murine cytomegalovirus late transcription complex
Chapa, T. J., Du, Y., Sun, R., Yu, D. & French, A. R., Feb 2017, In: Journal of General Virology. 98, 2, p. 242-250 9 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Serologic evidence of gut-driven systemic inflammation in juvenile idiopathic arthritis
Fotis, L., Shaikh, N., Baszis, K. W., Samson, C. M., Lev-Tzion, R., French, A. R. & Tarr, P. I., Nov 1 2017, In: Journal of Rheumatology. 44, 11, p. 1624-1631 8 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
2016
Deficiency of the adaptor protein SLy1 results in a natural killer cell ribosomopathy affecting tumor clearance
Arefanian, S., Schäll, D., Chang, S., Ghasemi, R., Higashikubo, R., Zheleznyak, A., Guo, Y., Yu, J., Asgharian, H., Li, W., Gelman, A. E., Kreisel, D., French, A. R., Zaher, H., Plougastel-Douglas, B., Maggi, L., Yokoyama, W., Beer-Hammer, S. & Krupnick, A. S., Dec 1 2016, In: OncoImmunology. 5, 12, e1238543.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2015
Type i interferons link viral infection to enhanced epithelial turnover and repair
Sun, L., Miyoshi, H., Origanti, S., Nice, T. J., Barger, A. C., Manieri, N. A., Fogel, L. A., French, A. R., Piwnica-Worms, D., Piwnica-Worms, H., Virgin, H. W., Lenschow, D. J. & Stappenbeck, T. S., Jan 14 2015, In: Cell Host and Microbe. 17, 1, p. 85-97 13 p.Research output: Contribution to journal › Article › peer-review
Open Access76 Scopus citations -
2014
Elevated double negative T cells in pediatric autoimmunity
Tarbox, J. A., Keppel, M. P., Topcagic, N., Mackin, C., Ben Abdallah, M., Baszis, K. W., White, A. J., French, A. R. & Cooper, M. A., Jul 2014, In: Journal of Clinical Immunology. 34, 5, p. 594-599 6 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
Murine cytomegalovirus protein pM92 Is a conserved regulator of viral late gene expression
Chapa, T. J., Perng, Y. C., French, A. R. & Yu, D., Jan 2014, In: Journal of virology. 88, 1, p. 131-142 12 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
2013
Hypogammaglobulinemia in pediatric systemic lupus erythematosus
Lim, E., Tao, Y., White, A. J., French, A. R. & Cooper, M. A., Nov 2013, In: Lupus. 22, 13, p. 1382-1387 6 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signaling
Sauer, K., Park, E., Siegemund, S., French, A. R., Wahle, J. A., Sternberg, L., Rigaud, S., Jonsson, A. H., Yokoyama, W. M. & Huang, Y. H., Jan 10 2013, In: Blood. 121, 2, p. 286-297 12 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Markers of nonselective and specific NK cell activation
Fogel, L. A., Sun, M. M., Geurs, T. L., Carayannopoulos, L. N. & French, A. R., Jun 15 2013, In: Journal of Immunology. 190, 12, p. 6269-6276 8 p.Research output: Contribution to journal › Article › peer-review
Open Access54 Scopus citations -
Mechanistic Model of Natural Killer Cell Proliferative Response to IL-15 Receptor Stimulation
Zhao, Y. M. & French, A. R., Sep 2013, In: PLoS computational biology. 9, 9, e1003222.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
MicroRNA-155 tunes both the threshold and extent of NK cell activation via targeting of multiple signaling pathways
Sullivan, R. P., Fogel, L. A., Leong, J. W., Schneider, S. E., Wong, R., Romee, R., Thai, T. H., Sexl, V., Matkovich, S. J., Dorn, G. W., French, A. R. & Fehniger, T. A., Dec 15 2013, In: Journal of Immunology. 191, 12, p. 5904-5913 10 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
Natural killer cell functional defects in pediatric patients with severe and recurrent herpesvirus infections
Ornstein, B. W., Hill, E. B., Geurs, T. L. & French, A. R., Feb 1 2013, In: Journal of Infectious Diseases. 207, 3, p. 458-468 11 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
2012
Activation Mechanisms of Natural Killer Cells during Influenza Virus Infection
Hwang, I., Scott, J. M., Kakarla, T., Duriancik, D. M., Choi, S., Cho, C., Lee, T., Park, H., French, A. R., Beli, E., Gardner, E. & Kim, S., Dec 31 2012, In: PloS one. 7, 12, e51858.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
MicroRNA-deficient NK cells exhibit decreased survival but enhanced function
Sullivan, R. P., Leong, J. W., Schneider, S. E., Keppel, C. R., Germino, E., French, A. R. & Fehniger, T. A., Apr 1 2012, In: Journal of Immunology. 188, 7, p. 3019-3030 12 p.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
Recurrent parotitis as a presentation of primary pediatric Sjögren syndrome
Baszis, K., Toib, D., Cooper, M., French, A. & White, A., Jan 2012, In: Pediatrics. 129, 1, p. e179-e182Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
Sex differences in murine susceptibility to systemic viral infections
Geurs, T. L., Hill, E. B., Lippold, D. M. & French, A. R., May 2012, In: Journal of Autoimmunity. 38, 2-3, p. J245-J253Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
The use of electroconvulsive therapy in a patient with juvenile systemic lupus erythematosus and catatonia
Mon, T., L'Ecuyer, S., Farber, N. B., White, A. J., Baszis, K. W., Hearn, J. K., Spiegel, T. E., French, A. R. & Kitcharoensakkul, M., Dec 2012, In: Lupus. 21, 14, p. 1575-1581 7 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Two-compartment model of NK cell proliferation: Insights from population response to IL-15 stimulation
Zhao, Y. M. & French, A. R., Apr 1 2012, In: Journal of Immunology. 188, 7, p. 2981-2990 10 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
2011
Clinical outcomes after withdrawal of anti-tumor necrosis factor α therapy in patients with juvenile idiopathic arthritis: A twelve-year experience
Baszis, K., Garbutt, J., Toib, D., Mao, J., King, A., White, A. & French, A., Oct 2011, In: Arthritis and rheumatism. 63, 10, p. 3163-3168 6 p.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
2010
Cutting edge: FcR-like 5 on innate B cells is targeted by a poxvirus MHC class I-like immunoevasin
Campbell, J. A., Davis, R. S., Lilly, L. M., Fremont, D. H., French, A. R. & Carayannopoulos, L. N., Jul 1 2010, In: Journal of Immunology. 185, 1, p. 28-32 5 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
2009
Differential expression of granzyme B and C in murine cytotoxic lymphocytes
Cai, S. F., Fehniger, T. A., Cao, X., Mayer, J. C., Brune, J. D., French, A. R. & Ley, T. J., May 15 2009, In: Journal of Immunology. 182, 10, p. 6287-6297 11 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Ly49H engagement compensates for the absence of type I interferon signaling in stimulating NK cell proliferation during murine cytomegalovirus infection
Geurs, T. L., Zhao, Y. M., Hill, E. B. & French, A. R., Nov 1 2009, In: Journal of Immunology. 183, 9, p. 5830-5836 7 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
2008
HLA alleles determine differences in human natural killer cell responsiveness and potency
Kim, S., Sunwoo, J. B., Yang, L., Choi, T., Song, Y. J., French, A. R., Vlahiotis, A., Piccirillo, J. F., Cella, M., Colonna, M., Mohanakumar, T., Hsu, K. C., Dupont, B. & Yokoyama, W. M., Feb 26 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 8, p. 3053-3058 6 p.Research output: Contribution to journal › Article › peer-review
Open Access224 Scopus citations -
Ly49h is necessary for genetic resistance to murine cytomegalovirus
Cheng, T. P., French, A. R., Plougastel, B. F. M., Pingel, J. T., Orihuela, M. M., Buller, M. L. & Yokoyama, W. M., Oct 2008, In: Immunogenetics. 60, 10, p. 565-573 9 p.Research output: Contribution to journal › Article › peer-review
Open Access47 Scopus citations -
2007
Acquisition of Murine NK Cell Cytotoxicity Requires the Translation of a Pre-existing Pool of Granzyme B and Perforin mRNAs
Fehniger, T. A., Cai, S. F., Cao, X., Bredemeyer, A. J., Presti, R. M., French, A. R. & Ley, T. J., Jun 22 2007, In: Immunity. 26, 6, p. 798-811 14 p.Research output: Contribution to journal › Article › peer-review
Open Access353 Scopus citations -
Chronic lymphocytosis of functionally immature natural killer cells
French, A. R., Kim, S., Fehniger, T. A., Pratt, J. R., Yang, L., Song, Y. J., Caligiuri, M. A. & Yokoyama, W. M., Oct 2007, In: Journal of Allergy and Clinical Immunology. 120, 4, p. 924-931 8 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2006
Arrested natural killer cell development associated with transgene insertion into the Atf2 locus
Kim, S., Song, Y. J., Higuchi, D. A., Kang, H. P., Pratt, J. R., Yang, L., Hong, C. M., Poursine-Laurent, J., Iizuka, K., French, A. R., Sunwoo, J. B., Ishii, S., Reimold, A. M. & Yokoyama, W. M., Feb 1 2006, In: Blood. 107, 3, p. 1024-1030 7 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
DAP12 signaling directly augments proproliferative cytokine stimulation of NK cells during viral infections
French, A. R., Sjölin, H., Kim, S., Koka, R., Yang, L., Young, D. A., Cerboni, C., Tomasello, E., Ma, A., Vivier, E., Kärre, K. & Yokoyama, W. M., Oct 15 2006, In: Journal of Immunology. 177, 8, p. 4981-4990 10 p.Research output: Contribution to journal › Article › peer-review
Open Access63 Scopus citations -
IL-18 acts synergistically with IL-15 in stimulating natural killer cell proliferation
French, A. R., Holroyd, E. B., Yang, L., Kim, S. & Yokoyama, W. M., Sep 2006, In: Cytokine. 35, 5-6, p. 229-234 6 p.Research output: Contribution to journal › Article › peer-review
62 Scopus citations -
2005
A lymphotoxin-IFN-β axis essential for lymphocyte survival revealed during cytomegalovirus infection
Banks, T. A., Rickert, S., Benedict, C. A., Ma, L., Ko, M., Meier, J., Ha, W., Schneider, K., Granger, S. W., Turovskaya, O., Elewaut, D., Otero, D., French, A. R., Henry, S. C., Hamilton, J. D., Scheu, S., Pfeffer, K. & Ware, C. F., Jun 1 2005, In: Journal of Immunology. 174, 11, p. 7217-7225 9 p.Research output: Contribution to journal › Article › peer-review
Open Access73 Scopus citations -
Licensing of natural killer cells by host major histocompatibility complex class I molecules
Kim, S., Poursine-Laurent, J., Truscott, S. M., Lybarger, L., Song, Y. J., Yang, L., French, A. R., Sunwoo, J. B., Lemieux, S., Hansen, T. H. & Yokoyama, W. M., Aug 4 2005, In: Nature. 436, 7051, p. 709-713 5 p.Research output: Contribution to journal › Article › peer-review
1082 Scopus citations -
Rapid emergence of escape mutants following infection with murine cytomegalovirus in immunodeficient mice
French, A. R., Pingel, J. T., Kim, S., Yang, L. & Yokoyama, W. M., Apr 2005, In: Clinical Immunology. 115, 1 SPEC. ISS., p. 61-69 9 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
2004
Coordinate Expression of Cytokines and Chemokines by NK Cells during Murine Cytomegalovirus Infection
Dorner, B. G., Smith, H. R. C., French, A. R., Kim, S., Poursine-Laurent, J., Beckman, D. L., Pingel, J. T., Kroczek, R. A. & Yokoyama, W. M., Mar 1 2004, In: Journal of Immunology. 172, 5, p. 3119-3131 13 p.Research output: Contribution to journal › Article › peer-review
Open Access110 Scopus citations -
Escape of mutant double-stranded DNA virus from innate immune control
French, A. R., Pingel, J. T., Wagner, M., Bubic, I., Yang, L., Kim, S., Koszinowski, U., Jonjic, S. & Yokoyama, W. M., Jun 2004, In: Immunity. 20, 6, p. 747-756 10 p.Research output: Contribution to journal › Article › peer-review
Open Access104 Scopus citations -
TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function
Krug, A., French, A. R., Barchet, W., Fischer, J. A. A., Dzionek, A., Pingel, J. T., Orihuela, M. M., Akira, S., Yokoyama, W. M. & Colonna, M., Jul 2004, In: Immunity. 21, 1, p. 107-119 13 p.Research output: Contribution to journal › Article › peer-review
Open Access623 Scopus citations -
2002
In vivo developmental stages in murine natural killer cell maturation
Kim, S., Iizuka, K., Kang, H. S. P., Dokun, A., French, A. R., Greco, S. & Yokoyama, W. M., 2002, In: Nature immunology. 3, 6, p. 523-528 6 p.Research output: Contribution to journal › Article › peer-review
504 Scopus citations -
Osteopenia in adults with a history of juvenile rheumatoid arthritis. A population based study
French, A. R., Mason, T., Nelson, A. M., Crowson, C. S., O'Fallon, W. M., Khosla, S. & Gabriel, S. E., 2002, In: Journal of Rheumatology. 29, 5, p. 1065-1070 6 p.Research output: Contribution to journal › Article › peer-review
59 Scopus citations -
2001
Increased mortality in adults with a history of juvenile rheumatoid arthritis: A population-based study
French, A. R., Mason, T., Nelson, A. M., O'Fallon, W. M. & Gabriel, S. E., 2001, In: Arthritis and rheumatism. 44, 3, p. 523-527 5 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
1997
Controlling receptor/ligand trafficking: Effects of cellular and molecular properties on endosomal sorting
French, A. R. & Lauffenburger, D. A., 1997, In: Annals of biomedical engineering. 25, 4, p. 690-707 18 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
1996
Engineering dynamics of growth factors and other therapeutic ligands
Lauffenburger, D. A., Chu, L., French, A., Oehrtman, G., Reddy, C., Wells, A., Niyogi, S. & Wiley, H. S., Oct 5 1996, In: Biotechnology and Bioengineering. 52, 1, p. 61-80 20 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations