• 19820 Citations
1987 …2020

Research output per year

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Personal profile

Research interests

Dr. Cross' main interest involves lymphocyte migration to the central nervous system (CNS) and cell-mediated factors underlying demyelination and axon injury, including cytokines, chemokines and free radicals. Dr. Cross employs a mouse model of relapsing/remitting inflammatory CNS demyelination (experimental allergic encephalomyelitis) in these studies. Using information gained through all of these studies, our goal is to modulate the pathogenic lymphocytes in the mouse model, and eventually in humans with MS, to prevent CNS injury. The Cross laboratory is also interested in the role of B lymphocytes in MS, and is near completion of a clinical trial using B cell depletion in MS patients who have not responded optimally to standard therapies alone.

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Research Output

Can CSF biomarkers predict future MS disease activity and severity?

Magliozzi, R. & Cross, A. H., Apr 1 2020, In : Multiple Sclerosis Journal. 26, 5, p. 582-590 9 p.

Research output: Contribution to journalArticle

  • 4 Scopus citations
  • 1 Scopus citations

    Clinical instrument to retrospectively capture levels of EDSS

    Ciotti, J. R., Sanders, N., Salter, A., Berger, J. R., Cross, A. H. & Chahin, S., Apr 2020, In : Multiple Sclerosis and Related Disorders. 39, 101884.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Deep learning with diffusion basis spectrum imaging for classification of multiple sclerosis lesions

    Ye, Z., George, A., Wu, A. T., Niu, X., Lin, J., Adusumilli, G., Naismith, R. T., Cross, A. H., Sun, P. & Song, S. K., May 1 2020, In : Annals of Clinical and Translational Neurology. 7, 5, p. 695-706 12 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Diffusion basis spectrum imaging provides insights into MS pathology

    Sun, P., George, A., Perantie, D. C., Trinkaus, K., Ye, Z., Naismith, R. T., Song, S. K. & Cross, A. H., Mar 1 2020, In : Neurology(R) neuroimmunology & neuroinflammation. 7, 2

    Research output: Contribution to journalArticle

    Open Access
  • 3 Scopus citations