Angela Hobson’s previous research focused on environmental health. She has studied occupational exposure assessment methodology for Parkinsonism among welders, heavy metal contamination assessment in the Peruvian Andes, and asthma management programs for low-income students in urban schools. She has also collaborated on pedagogical research related to teaching environmental health to medical students. Hobson' s research interests also include the scholarship of teaching and learning in competency-based public health curriculum.

Hobson is a member of and regular contributor to the Academic Affairs Section of the Association for Schools and Programs in Public Health (ASPPH).

Hobson is the associate dean for education at WashU School of Public Health. In this role, she oversees the curriculum for MPH and PhD students, including coursework and teaching and field applied practice experiences; coordinates student recruitment and admissions; and provides support to teaching faculty. Hobson also teaches graduate-level courses on public health and leadership, environmental health and epidemiology.