Andrew Heath

Article

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

Rietveld, C. A., Medland, S. E., Derringer, J., Yang, J., Esko, T., Martin, N. W., Westra, H. J., Shakhbazov, K., Abdellaoui, A., Agrawal, A., Albrecht, E., Alizadeh, B. Z., Amin, N., Barnard, J., Baumeister, S. E., Benke, K. S., Bielak, L. F., Boatman, J. A., Boyle, P. A., Davies, G., & 183 othersDe Leeuw, C., Eklund, N., Evans, D. S., Ferhmann, R., Fischer, K., Gieger, C., Gjessing, H. K., Hägg, S., Harris, J. R., Hayward, C., Holzapfel, C., Ibrahim-Verbaas, C. A., Ingelsson, E., Jacobsson, B., Joshi, P. K., Jugessur, A., Kaakinen, M., Kanoni, S., Karjalainen, J., Kolcic, I., Kristiansson, K., Kutalik, Z., Lahti, J., Lee, S. H., Lin, P., Lind, P. A., Liu, Y., Lohman, K., Loitfelder, M., McMahon, G., Vidal, P. M., Meirelles, O., Milani, L., Myhre, R., Nuotio, M. L., Oldmeadow, C. J., Petrovic, K. E., Peyrot, W. J., Polašek, O., Quaye, L., Reinmaa, E., Rice, J. P., Rizzi, T. S., Schmidt, H., Schmidt, R., Smith, A. V., Smith, J. A., Tanaka, T., Terracciano, A., Van Der Loos, M. J. H. M., Vitart, V., Völzke, H., Wellmann, J., Yu, L., Zhao, W., Allik, J., Attia, J. R., Bandinelli, S., Bastardot, F., Beauchamp, J., Bennett, D. A., Berger, K., Bierut, L. J., Boomsma, D. I., Bültmann, U., Campbell, H., Chabris, C. F., Cherkas, L., Chung, M. K., Cucca, F., De Andrade, M., De Jager, P. L., De Neve, J. E., Deary, I. J., Dedoussis, G. V., Deloukas, P., Dimitriou, M., Eiríksdóttir, G., Elderson, M. F., Eriksson, J. G., Evans, D. M., Faul, J. D., Ferrucci, L., Garcia, M. E., Grönberg, H., Guonason, V., Hall, P., Harris, J. M., Harris, T. B., Hastie, N. D., Heath, A. C., Hernandez, D. G., Hoffmann, W., Hofman, A., Holle, R., Holliday, E. G., Hottenga, J. J., Iacono, W. G., Illig, T., Järvelin, M. R., Kähönen, M., Kaprio, J., Kirkpatrick, R. M., Kowgier, M., Latvala, A., Launer, L. J., Lawlor, D. A., Lehtimäki, T., Li, J., Lichtenstein, P., Lichtner, P., Liewald, D. C., Madden, P. A., Magnusson, P. K. E., Mäkinen, T. E., Masala, M., McGue, M., Metspalu, A., Mielck, A., Miller, M. B., Montgomery, G. W., Mukherjee, S., Nyholt, D. R., Oostra, B. A., Palmer, L. J., Palotie, A., Penninx, B. W. J. H., Perola, M., Peyser, P. A., Preisig, M., Räikkönen, K., Raitakari, O. T., Realo, A., Ring, S. M., Ripatti, S., Rivadeneira, F., Rudan, I., Rustichini, A., Salomaa, V., Sarin, A. P., Schlessinger, D., Scott, R. J., Snieder, H., St Pourcain, B., Starr, J. M., Sul, J. H., Surakka, I., Svento, R., Teumer, A., Tiemeier, H., Van Rooij, F. J. A., Van Wagoner, D. R., Vartiainen, E., Viikari, J., Vollenweider, P., Vonk, J. M., Waeber, G., Weir, D. R., Wichmann, H. E., Widen, E., Willemsen, G., Wilson, J. F., Wright, A. F., Conley, D., Davey-Smith, G., Franke, L., Groenen, P. J. F., Hofman, A., Johannesson, M., Kardia, S. L. R., Krueger, R. F., Laibson, D., Martin, N. G., Meyer, M. N., Posthuma, D., Thurik, A. R., Timpson, N. J., Uitterlinden, A. G., Van Duijn, C. M., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D., 2013, In: Science. 340, 6139, p. 1467-1471 5 p.

Research output: Contribution to journal › Article › peer-review

530 Scopus citations

GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors

Benyamin, B., Middelberg, R. P., Lind, P. A., Valle, A. M., Gordon, S., Nyholt, D. R., Medland, S. E., Henders, A. K., Heath, A. C., Madden, P. A. F., Visscher, P. M., O'Connor, D. T., Montgomery, G. W., Martin, N. G. & Whitfield, J. B., Nov 2011, In: Human molecular genetics. 20, 22, p. 4504-4514 11 p., ddr375.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia

the 23andMe Research Team, The Substance Use Disorders Working Group of the Psychiatric Genomics Consortium & International Cannabis Consortium, Sep 1 2018, In: Nature neuroscience. 21, 9, p. 1161-1170 10 p.

Research output: Contribution to journal › Article › peer-review

244 Scopus citations

H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for alcohol consumption and dependence

Nelson, E. C., Agrawal, A., Pergadia, M. L., Wang, J. C., Whitfield, J. B., Saccone, F. S., Kern, J., Grant, J. D., Schrage, A. J., Rice, J. P., Montgomery, G. W., Heath, A. C., Goate, A. M., Martin, N. G. & Madden, P. A. F., Jan 2010, In: Addiction Biology. 15, 1, p. 1-11 11 p.

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Habitual sleep disturbances and migraine: a Mendelian randomization study

International Headache Genetics Consortium, Dec 2020, In: Annals of Clinical and Translational Neurology. 7, 12, p. 2370-2380 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

Rietschel, L., Streit, F., Zhu, G., McAloney, K., Frank, J., Couvy-Duchesne, B., Witt, S. H., Binz, T. M., Bolton, J. L., Hayward, C., Direk, N., Anderson, A., Huffman, J., Wilson, J. F., Campbell, H., Rudan, I., Wright, A., Hastie, N., Wild, S. H., Velders, F. P., & 215 othersHofman, A., Uitterlinden, A. G., Lahti, J., Räikkönen, K., Kajantie, E., Widen, E., Palotie, A., Eriksson, J. G., Kaakinen, M., Järvelin, M. R., Timpson, N. J., Davey Smith, G., Ring, S. M., Evans, D. M., St Pourcain, B., Tanaka, T., Milaneschi, Y., Bandinelli, S., Ferrucci, L., Van Der Harst, P., Rosmalen, J. G., Bakker, S. J., Verweij, N., Dullaart, R. P., Mahajan, A., Lindgren, C. M., Morris, A., Lind, L., Ingelsson, E., Anderson, L. N., Pennell, C. E., Lye, S. J., Matthews, S. G., Eriksson, J., Mellstrom, D., Ohlsson, C., Price, J. F., Strachan, M. W., Reynolds, R. M., Tiemeier, H., Ripke, S., Mattheisen, M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T., Bennett, D. A., Berger, K., Bigdeli, T. B., Bybjerg-Grauholm, J., Byrne, E. M., Cai, N., Castelao, E., Clarke, T. K., Coleman, J. R., Consortium, C., Craddock, N., Dannlowski, U., Davies, G., Davies, G., De Geus, E. J. C., De Jager, P., Deary, I. J., Degenhardt, F., Dunn, E. C., Ehli, E. A., Eley, T. C., Escott-Price, V., Esko, T., Finucane, H. K., Gill, M., Gordon, S. D., Grove, J., Hall, L. S., Hansen, T. F., Søholm Hansen, C., Heath, A. C., Henders, A. K., Herms, S., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D., Huang, H., Ising, M., Jansen, R., Jorgenson, E., Kloiber, S., Knowles, J. A., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Lang, M., Lewis, G., Li, Y., MacIntyre, D. J., Madden, P. A., Marchine, J., Mbarek, H., McGuffin, P., Mehta, D., Metspalu, A., Middeldorp, C. M., Mihailov, E., Milani, L., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nordentoft, M., Nyholt, D. R., O'Donovan, M. C., O'Reilly, P. F., Oskarsson, H., Owen, M. J., Paciga, S. A., Pedersen, C. B., Pedersen, M. G., Pedersen, N. L., Pergadia, M. L., Peterson, R. E., Pettersson, E., Peyrot, W. J., Porteous, D. J., Posthuma, D., Potash, J. B., Quiroz, J. A., Rice, J. P., Riley, B. P., Rivera, M., Ruderfer, D. M., Saeed Mirza, S., Schoevers, R., Shen, L., Shi, J., Sigurdsson, E., Sinnamon, G. C., Smit, J. H., Smith, D. J., Stephansson, H., Steinberg, S., Strohmaier, J., Tansey, K. E., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Treutlein, J., Trzaskowski, M., Umbricht, D., Van Der Auwera, S., Van Grootheest, G., Van Hemert, A. M., Viktorin, A., Völzke, H., Wang, Y., Webb, B. T., Weissman, M. M., Wellmann, J., Willemsen, G., Xi, H. S., Baune, B. T., Blackwood, D. H. R., Boomsma, D. I., Børglum, A. D., Buttenschøn, H. N., Cichon, S., Domenici, E., Flint, J., Grabe, H. J., Hamilton, S. P., Kendler, K. S., Li, Q. S., Lucae, S., Magnusson, P. K., McIntosh, A. M., Mors, O., Bo Mortensen, P., Müller-Myhsok, B., Penninx, B. W., Perlis, R. H., Preisig, M., Schaefer, C., Smoller, J. W., Stephansson, K., Uher, R., Werge, T., Winslow, A. R., Breen, G., Levinson, D. F., Lewis, C. M., Wray, N. R., Sullivan, P. F., McGrath, J., Hickie, I. B., Hansell, N. K., Wright, M. J., Gillespie, N. A., Forstner, A. J., Schulze, T. G., Wüst, S., Nöthen, M. M., Baumgartner, M. R., Walker, B. R., Crawford, A. A., Colodro-Conde, L., Medland, S. E., Martin, N. G. & Rietschel, M., Dec 1 2017, In: Scientific reports. 7, 1, 15351.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

Harmonization of neuroticism and extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: An application of item response theory

Van Den Berg, S. M., De Moor, M. H. M., McGue, M., Pettersson, E., Terracciano, A., Verweij, K. J. H., Amin, N., Derringer, J., Esko, T., Van Grootheest, G., Hansell, N. K., Huffman, J., Konte, B., Lahti, J., Luciano, M., Matteson, L. K., Viktorin, A., Wouda, J., Agrawal, A., Allik, J., & 68 othersBierut, L., Broms, U., Campbell, H., Smith, G. D., Eriksson, J. G., Ferrucci, L., Franke, B., Fox, J. P., De Geus, E. J. C., Giegling, I., Gow, A. J., Grucza, R., Hartmann, A. M., Heath, A. C., Heikkilä, K., Iacono, W. G., Janzing, J., Jokela, M., Kiemeney, L., Lehtimäki, T., Madden, P. A. F., Magnusson, P. K. E., Northstone, K., Nutile, T., Ouwens, K. G., Palotie, A., Pattie, A., Pesonen, A. K., Polasek, O., Pulkkinen, L., Pulkki-Råback, L., Raitakari, O. T., Realo, A., Rose, R. J., Ruggiero, D., Seppälä, I., Slutske, W. S., Smyth, D. C., Sorice, R., Starr, J. M., Sutin, A. R., Tanaka, T., Verhagen, J., Vermeulen, S., Vuoksimaa, E., Widen, E., Willemsen, G., Wright, M. J., Zgaga, L., Rujescu, D., Metspalu, A., Wilson, J. F., Ciullo, M., Hayward, C., Rudan, I., Deary, I. J., Räikkönen, K., Arias Vasquez, A., Costa, P. T., Keltikangas-Järvinen, L., Van Duijn, C. M., Penninx, B. W. J. H., Krueger, R. F., Evans, D. M., Kaprio, J., Pedersen, N. L., Martin, N. G. & Boomsma, D. I., Jul 2014, In: Behavior genetics. 44, 4, p. 295-313 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

83 Scopus citations

Height discordance in monozygotic females is not attributable to discordant inactivation of X-linked stature determining genes

Healey, S. C., Kirk, K. M., Hyland, V. J., Munns, C. F., Henders, A. K., Batch, J. A., Heath, A. C., Martin, N. G. & Glasss, I. A., Jan 1 2001, In: Twin Research. 4, 1, p. 19-24 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Heritability and nineteen-year stability of long and short EPQ-R neuroticism scales

Birley, A. J., Gillespie, N. A., Heath, A. C., Sullivan, P. F., Boomsma, D. I. & Martin, N. G., Mar 2006, In: Personality and Individual Differences. 40, 4, p. 737-747 11 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Heritability of brain activity related to response inhibition: A longitudinal genetic study in adolescent twins

Anokhin, A. P., Golosheykin, S., Grant, J. D. & Heath, A. C., May 1 2017, In: International Journal of Psychophysiology. 115, p. 112-124 13 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Heritability of delay discounting in adolescence: A longitudinal twin study

Anokhin, A. P., Golosheykin, S., Grant, J. D. & Heath, A. C., Mar 2011, In: Behavior genetics. 41, 2, p. 175-183 9 p.

Research output: Contribution to journal › Article › peer-review

165 Scopus citations

Heritability of frontal brain function related to action monitoring

Anokhin, A. P., Golosheykin, S. & Heath, A. C., Jul 2008, In: Psychophysiology. 45, 4, p. 524-534 11 p.

Research output: Contribution to journal › Article › peer-review

120 Scopus citations

Heritability of individual differences in cortical processing of facial affect

Anokhin, A. P., Golosheykin, S. & Heath, A. C., Mar 2010, In: Behavior genetics. 40, 2, p. 178-185 8 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Heritability of prefrontal lobe and subgenual prefrontal cortex volume in twins

Botteron, K., Sternhell, K., Singer, T., Raichle, M., Heath, A. & Todd, R., Dec 1 1999, In: NeuroImage. 9, 6 PART II, p. S673

Research output: Contribution to journal › Article › peer-review

Heritability of risk-taking in adolescence: A longitudinal twin study

Anokhin, A. P., Golosheykin, S., Grant, J. & Heath, A. C., Aug 2009, In: Twin Research and Human Genetics. 12, 4, p. 366-371 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Heritability of SF-36 among middle-age, middle-class, male-male twins

Romeis, J. C., Heath, A. C., Xian, H., Eisen, S. A., Scherrer, J. F., Pedersen, N. L., Fu, Q., Bucholz, K. K., Goldberg, J., Lyons, M. J., Waterman, B., Tsuang, M. T. & True, W. R., Nov 2005, In: Medical care. 43, 11, p. 1147-1154 8 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Higher Rates of DZ Twinning in a Twenty-First Century Birth Cohort

Rhea, S. A., Corley, R. P., Heath, A. C., Iacono, W. G., Neale, M. C. & Hewitt, J. K., Sep 1 2017, In: Behavior genetics. 47, 5, p. 581-584 4 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

HLA and genomewide allele sharing in dizygotic twins

Montgomery, G. W., Zhu, G., Hottenga, J. J., Duffy, D. L., Heath, A. C., Boomsma, D. I., Martin, N. G. & Visscher, P. M., Dec 2006, In: American journal of human genetics. 79, 6, p. 1052-1058 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Human parental behavior: Evidence for genetic influence and potential implication for gene-culture transmission

Pérusse, D., Neale, M. C., Heath, A. C. & Eaves, L. J., Jul 1994, In: Behavior genetics. 24, 4, p. 327-335 9 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Allen, H. L., Estrada, K., Lettre, G., Berndt, S. I., Weedon, M. N., Rivadeneira, F., Willer, C. J., Jackson, A. U., Vedantam, S., Raychaudhuri, S., Ferreira, T., Wood, A. R., Weyant, R. J., Segrè, A. V., Speliotes, E. K., Wheeler, E., Soranzo, N., Park, J. H., Yang, J., Gudbjartsson, D., & 273 othersHeard-Costa, N. L., Randall, J. C., Qi, L., Smith, A. V., Mägi, R., Pastinen, T., Liang, L., Heid, I. M., Luan, JA., Thorleifsson, G., Winkler, T. W., Goddard, M. E., Lo, K. S., Palmer, C., Workalemahu, T., Aulchenko, Y. S., Johansson, Å., Zillikens, M. C., Feitosa, M. F., Esko, T., Johnson, T., Ketkar, S., Kraft, P., Mangino, M., Prokopenko, I., Absher, D., Albrecht, E., Ernst, F., Glazer, N. L., Hayward, C., Hottenga, J. J., Jacobs, K. B., Knowles, J. W., Kutalik, Z., Monda, K. L., Polasek, O., Preuss, M., Rayner, N. W., Robertson, N. R., Steinthorsdottir, V., Tyrer, J. P., Voight, B. F., Wiklund, F., Xu, J., Zhao, J. H., Nyholt, D. R., Pellikka, N., Perola, M., Perry, J. B., Surakka, I., Tammesoo, M. L., Altmaier, E. L., Amin, N., Aspelund, T., Bhangale, T., Boucher, G., Chasman, D. I., Chen, C., Coin, L., Cooper, M. N., Dixon, A. L., Gibson, Q., Grundberg, E., Hao, K., Junttila, M. J., Kaplan, L. M., Kettunen, J., König, I. R., Kwan, T., Lawrence, R. W., Levinson, D. F., Lorentzon, M., McKnight, B., Morris, A. P., Müller, M., Ngwa, J. S., Purcell, S., Rafelt, S., Salem, R. M., Salvi, E., Sanna, S., Shi, J., Sovio, U., Thompson, J. R., Turchin, M. C., Vandenput, L., Verlaan, D. J., Vitart, V., White, C. C., Ziegler, A., Almgren, P., Balmforth, A. J., Campbell, H., Citterio, L., De Grandi, A., Dominiczak, A., Duan, J., Elliott, P., Elosua, R., Eriksson, J. G., Freimer, N. B., Geus, E. J. C., Glorioso, N., Haiqing, S., Hartikainen, A. L., Havulinna, A. S., Hicks, A. A., Hui, J., Igl, W., Illig, T., Jula, A., Kajantie, E., Kilpeläinen, T. O., Koiranen, M., Kolcic, I., Koskinen, S., Kovacs, P., Laitinen, J., Liu, J., Lokki, M. L., Marusic, A., Maschio, A., Meitinger, T., Mulas, A., Paré, G., Parker, A. N., Peden, J. F., Petersmann, A., Pichler, I., Pietiläinen, K. H., Pouta, A., Ridderstråle, M., Rotter, J. I., Sambrook, J. G., Sanders, A. R., Schmidt, C. O., Sinisalo, J., Smit, J. H., Stringham, H. M., Walters, G. B., Widen, E., Wild, S. H., Willemsen, G., Zagato, L., Zgaga, L., Zitting, P., Alavere, H., Farrall, M., McArdle, W. L., Nelis, M., Peters, M. J., Ripatti, S., Van Meurs, J. B. J., Aben, K. K., Ardlie, K. G., Beckmann, J. S., Beilby, J. P., Bergman, R. N., Bergmann, S., Collins, F. S., Cusi, D., Den Heijer, M., Eiriksdottir, G., Gejman, P. V., Hall, A. S., Hamsten, A., Huikuri, H. V., Iribarren, C., Kähönen, M., Kaprio, J., Kathiresan, S., Kiemeney, L., Kocher, T., Launer, L. J., Lehtimäki, T., Melander, O., Mosley, T. H., Musk, A. W., Nieminen, M. S., O'Donnell, C. J., Ohlsson, C., Oostra, B., Palmer, L. J., Raitakari, O., Ridker, P. M., Rioux, J. D., Rissanen, A., Rivolta, C., Schunkert, H., Shuldiner, A. R., Siscovick, D. S., Stumvoll, M., Tönjes, A., Tuomilehto, J., Van Ommen, G. J., Viikari, J., Heath, A. C., Martin, N. G., Montgomery, G. W., Province, M. A., Kayser, M., Arnold, A. M., D.Atwood, L., Boerwinkle, E., Chanock, S. J., Deloukas, P., Gieger, C., Grönberg, H., Hall, P., Hattersley, A. T., Hengstenberg, C., Hoffman, W., Lathrop, G. M., Salomaa, V., Schreiber, S., Uda, M., Waterworth, D., Wright, A. F., Assimes, T. L., Barroso, I., Hofman, A., Mohlke, K. L., Boomsma, D. I., Caulfield, M. J., Cupples, L. A., Erdmann, J., Fox, C. S., Gudnason, V., Gyllensten, U., Harris, T. B., Hayes, R. B., Jarvelin, M. R., Mooser, V., Munroe, P. B., Ouwehand, W. H., Penninx, B. W., Pramstaller, P. P., Quertermous, T., Rudan, I., Samani, N. J., Spector, T. D., Völzke, H., Watkins, H., Wilson, J. F., Groop, L. C., Haritunians, T., Hu, F. B., Kaplan, R. C., Metspalu, A., North, K. E., Schlessinger, D., Wareham, N. J., Hunter, D. J., O'Connell, J. R., Strachan, D. P., Wichmann, H. E., Borecki, I. B., Van Duijn, C. M., Schadt, E. E., Thorsteinsdottir, U., Peltonen, L., Uitterlinden, A. G., Visscher, P. M., Chatterjee, N., Loos, R. J. F., Boehnke, M., McCarthy, M. I., Ingelsson, E., Lindgren, C. M., Abecasis, G. R., Stefansson, K., Frayling, T. M. & Hirschhorn, J. N., Oct 14 2010, In: Nature. 467, 7317, p. 832-838 7 p.

Research output: Contribution to journal › Article › peer-review

783 Scopus citations

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23andMe Research Team, Mar 1 2019, In: Nature Genetics. 51, 3, p. 431-444 14 p.

Research output: Contribution to journal › Article › peer-review

887 Scopus citations

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

Australian Asthma Genetics Consortium, Sep 1 2011, In: The Lancet. 378, 9795, p. 1006-1014 9 p.

Research output: Contribution to journal › Article › peer-review

296 Scopus citations

Image processing and analysis methods for the Adolescent Brain Cognitive Development Study

Hagler, D. J., Hatton, S. N., Cornejo, M. D., Makowski, C., Fair, D. A., Dick, A. S., Sutherland, M. T., Casey, B. J., Barch, D. M., Harms, M. P., Watts, R., Bjork, J. M., Garavan, H. P., Hilmer, L., Pung, C. J., Sicat, C. S., Kuperman, J., Bartsch, H., Xue, F., Heitzeg, M. M., & 123 othersLaird, A. R., Trinh, T. T., Gonzalez, R., Tapert, S. F., Riedel, M. C., Squeglia, L. M., Hyde, L. W., Rosenberg, M. D., Earl, E. A., Howlett, K. D., Baker, F. C., Soules, M., Diaz, J., de Leon, O. R., Thompson, W. K., Neale, M. C., Herting, M., Sowell, E. R., Alvarez, R. P., Hawes, S. W., Sanchez, M., Bodurka, J., Breslin, F. J., Morris, A. S., Paulus, M. P., Simmons, W. K., Polimeni, J. R., van der Kouwe, A., Nencka, A. S., Gray, K. M., Pierpaoli, C., Matochik, J. A., Noronha, A., Aklin, W. M., Conway, K., Glantz, M., Hoffman, E., Little, R., Lopez, M., Pariyadath, V., Weiss, S. RB., Wolff-Hughes, D. L., DelCarmen-Wiggins, R., Feldstein Ewing, S. W., Miranda-Dominguez, O., Nagel, B. J., Perrone, A. J., Sturgeon, D. T., Goldstone, A., Pfefferbaum, A., Pohl, K. M., Prouty, D., Uban, K., Bookheimer, S. Y., Dapretto, M., Galvan, A., Bagot, K., Giedd, J., Infante, M. A., Jacobus, J., Patrick, K., Shilling, P. D., Desikan, R., Li, Y., Sugrue, L., Banich, M. T., Friedman, N., Hewitt, J. K., Hopfer, C., Sakai, J., Tanabe, J., Cottler, L. B., Nixon, S. J., Chang, L., Cloak, C., Ernst, T., Reeves, G., Kennedy, D. N., Heeringa, S., Peltier, S., Schulenberg, J., Sripada, C., Zucker, R. A., Iacono, W. G., Luciana, M., Calabro, F. J., Clark, D. B., Lewis, D. A., Luna, B., Schirda, C., Brima, T., Foxe, J. J., Freedman, E. G., Mruzek, D. W., Mason, M. J., Huber, R., McGlade, E., Prescot, A., Renshaw, P. F., Yurgelun-Todd, D. A., Allgaier, N. A., Dumas, J. A., Ivanova, M., Potter, A., Florsheim, P., Larson, C., Lisdahl, K., Charness, M. E., Fuemmeler, B., Hettema, J. M., Maes, H. H., Steinberg, J., Anokhin, A. P., Glaser, P., Heath, A. C., Madden, P. A., Baskin-Sommers, A., Constable, R. T., Grant, S. J., Dowling, G. J., Brown, S. A., Jernigan, T. L. & Dale, A. M., Nov 15 2019, In: NeuroImage. 202, 116091.

Research output: Contribution to journal › Article › peer-review

274 Scopus citations

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

Hartz, S. M., Short, S. E., Saccone, N. L., Culverhouse, R., Chen, L. S., Schwantes-An, T. H., Coon, H., Han, Y., Stephens, S. H., Sun, J., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Geller, F., Guobjartsson, D., Hansel, N. N., Jiang, C., Keskitalo-Vuokko, K., & 132 othersLiu, Z., Lyytikäinen, L. P., Michel, M., Rawal, R., Rosenberger, A., Scheet, P., Shaffer, J. R., Teumer, A., Thompson, J. R., Vink, J. M., Vogelzangs, N., Wenzlaff, A. S., Wheeler, W., Xiao, X., Yang, B. Z., Aggen, S. H., Balmforth, A. J., Baumeister, S. E., Beaty, T., Bennett, S., Bergen, A. W., Boyd, H. A., Broms, U., Campbell, H., Chatterjee, N., Chen, J., Cheng, Y. C., Cichon, S., Couper, D., Cucca, F., Dick, D. M., Foroud, T., Furberg, H., Giegling, I., Gu, F., Hall, A. S., Hällfors, J., Han, S., Hartmann, A. M., Hayward, C., Heikkilä, K., Hewitt, J. K., Hottenga, J. J., Jensen, M. K., Jousilahti, P., Kaakinen, M., Kittner, S. J., Konte, B., Korhonen, T., Landi, M. T., Laatikainen, T., Leppert, M., Levy, S. M., Mathias, R. A., McNeil, D. W., Medland, S. E., Montgomery, G. W., Muley, T., Murray, T., Nauck, M., North, K., Pergadia, M., Polasek, O., Ramos, E. M., Ripatti, S., Risch, A., Ruczinski, I., Rudan, I., Salomaa, V., Schlessinger, D., Styrkársdóttir, U., Terracciano, A., Uda, M., Willemsen, G., Wu, X., Abecasis, G., Barnes, K., Bickeböller, H., Boerwinkle, E., Boomsma, D. I., Caporaso, N., Duan, J., Edenberg, H. J., Francks, C., Gejman, P. V., Gelernter, J., Grabe, H. J., Hops, H., Jarvelin, M. R., Viikari, J., Kähönen, M., Kendler, K. S., Lehtimäki, T., Levinson, D. F., Marazita, M. L., Marchini, J., Melbye, M., Mitchell, B. D., Murray, J. C., Nöthen, M. M., Penninx, B. W., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N. J., Sanders, A. R., Schwartz, A. G., Shete, S., Shi, J., Spitz, M., Stefansson, K., Swan, G. E., Thorgeirsson, T., Völzke, H., Wei, Q., Wichmann, H. E., Amos, C. I., Breslau, N., Cannon, D. S., Ehringer, M., Grucza, R., Hatsukami, D., Heath, A., Johnson, E. O., Kaprio, J., Madden, P., Martin, N. G., Stevens, V. L., Stitzel, J. A., Weiss, R. B., Kraft, P. & Bierut, L. J., Aug 2012, In: Archives of General Psychiatry. 69, 8, p. 854-861 8 p.

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Inference of the genetic architecture underlying bmi and height with the use of 20,240 sibling pairs

Hemani, G., Yang, J., Vinkhuyzen, A., Powell, J. E., Willemsen, G., Hottenga, J. J., Abdellaoui, A., Mangino, M., Valdes, A. M., Medland, S. E., Madden, P. A., Heath, A. C., Henders, A. K., Nyholt, D. R., De Geus, E. J. C., Magnusson, P. K. E., Ingelsson, E., Montgomery, G. W., Spector, T. D., Boomsma, D. I., & 3 othersPedersen, N. L., Martin, N. G. & Visscher, P. M., Nov 7 2013, In: American journal of human genetics. 93, 5, p. 865-875 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

70 Scopus citations

Inhibitory control in siblings discordant for exposure to maternal smoking during pregnancy

Micalizzi, L., Marceau, K., Brick, L. A., Palmer, R. H., Todorov, A. A., Heath, A. C., Evans, A. & Knopik, V. S., Feb 1 2018, In: Developmental Psychology. 54, 2, p. 199-208 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Initial reactions to tobacco and cannabis smoking: A twin study

Agrawal, A., Madden, P. A. F., Bucholz, K. K., Heath, A. C. & Lynskey, M. T., Apr 2014, In: Addiction. 109, 4, p. 663-671 9 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 1 2019, In: Nature communications. 10, 1, 2548.

Research output: Contribution to journal › Article › peer-review

Open Access

69 Scopus citations

Interaction between the DRD4 VNTR polymorphism and proximal and distal environments in alcohol dependence during emerging and young adulthood

Park, A., Sher, K. J., Todorov, A. A. & Heath, A. C., Aug 2011, In: Journal of Abnormal Psychology. 120, 3, p. 585-595 11 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Interaction of marital status and genetic risk for symptoms of depression

Heath, A. C., Eaves, L. J. & Martin, N. G., 1998, In: Twin Research. 1, 3, p. 119-122 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Interactive effect of genotype and social environment on alcohol consumption in female twins

Heath, A. C., Jardine, R. & Martin, N. G., 1989, In: Journal of Studies on Alcohol. 50, 1, p. 38-48 11 p.

Research output: Contribution to journal › Article › peer-review

100 Scopus citations

Interactive Effects of Maternal Alcohol Problems and Parental Separation on Timing of Daughter's First Drink

Waldron, M., Watkins, N. K., Bucholz, K. K., Madden, P. A. F. & Heath, A. C., Jan 2018, In: Alcoholism: Clinical and Experimental Research. 42, 1, p. 120-127 8 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Intergenerational transmission of childhood conduct problems: A children of twins study

D'Onofrio, B. M., Slutske, W. S., Turkheimer, E., Emery, R. E., Harden, K. P., Heath, A. C., Madden, P. A. F. & Martin, N. G., Jul 2007, In: Archives of General Psychiatry. 64, 7, p. 820-829 10 p.

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C. Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., Levey, D. F., Logue, M. W., Polimanti, R., Provost, A. C., Ratanatharathorn, A., Stein, M. B., Torres, K., Aiello, A. E., Almli, L. M., Amstadter, A. B., & 159 othersAndersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegovic, E., Babić, D., Bækvad-Hansen, M., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J. I., Boks, M. P., Bolger, E. A., Børglum, A. D., Bradley, B., Brashear, M., Breen, G., Bryant, R. A., Bustamante, A. C., Bybjerg-Grauholm, J., Calabrese, J. R., Caldas- de- Almeida, J. M., Dale, A. M., Daly, M. J., Daskalakis, N. P., Deckert, J., Delahanty, D. L., Dennis, M. F., Disner, S. G., Domschke, K., Dzubur-Kulenovic, A., Erbes, C. R., Evans, A., Farrer, L. A., Feeny, N. C., Flory, J. D., Forbes, D., Franz, C. E., Galea, S., Garrett, M. E., Gelaye, B., Geuze, E., Gillespie, C., Uka, A. G., Gordon, S. D., Guffanti, G., Hammamieh, R., Harnal, S., Hauser, M. A., Heath, A. C., Hemmings, S. M. J., Hougaard, D. M., Jakovljevic, M., Jett, M., Johnson, E. O., Jones, I., Jovanovic, T., Qin, X. J., Junglen, A. G., Karstoft, K. I., Kaufman, M. L., Kessler, R. C., Khan, A., Kimbrel, N. A., King, A. P., Koen, N., Kranzler, H. R., Kremen, W. S., Lawford, B. R., Lebois, L. A. M., Lewis, C. E., Linnstaedt, S. D., Lori, A., Lugonja, B., Luykx, J. J., Lyons, M. J., Maples-Keller, J., Marmar, C., Martin, A. R., Martin, N. G., Maurer, D., Mavissakalian, M. R., McFarlane, A., McGlinchey, R. E., McLaughlin, K. A., McLean, S. A., McLeay, S., Mehta, D., Milberg, W. P., Miller, M. W., Morey, R. A., Morris, C. P., Mors, O., Mortensen, P. B., Neale, B. M., Nelson, E. C., Nordentoft, M., Norman, S. B., O’Donnell, M., Orcutt, H. K., Panizzon, M. S., Peters, E. S., Peterson, A. L., Peverill, M., Pietrzak, R. H., Polusny, M. A., Rice, J. P., Ripke, S., Risbrough, V. B., Roberts, A. L., Rothbaum, A. O., Rothbaum, B. O., Roy-Byrne, P., Ruggiero, K., Rung, A., Rutten, B. P. F., Saccone, N. L., Sanchez, S. E., Schijven, D., Seedat, S., Seligowski, A. V., Seng, J. S., Sheerin, C. M., Silove, D., Smith, A. K., Smoller, J. W., Sponheim, S. R., Stein, D. J., Stevens, J. S., Sumner, J. A., Teicher, M. H., Thompson, W. K., Trapido, E., Uddin, M., Ursano, R. J., van den Heuvel, L. L., Van Hooff, M., Vermetten, E., Vinkers, C. H., Voisey, J., Wang, Y., Wang, Z., Werge, T., Williams, M. A., Williamson, D. E., Winternitz, S., Wolf, C., Wolf, E. J., Wolff, J. D., Yehuda, R., Young, R. M. D., Young, K. A., Zhao, H., Zoellner, L. A., Liberzon, I., Ressler, K. J., Haas, M. & Koenen, K. C., Dec 1 2019, In: Nature communications. 10, 1, 4558.

Research output: Contribution to journal › Article › peer-review

Open Access

204 Scopus citations

Interrelationship of genetic and environmental influences on conduct disorder and alcohol and marijuana dependence symptoms

True, W. R., Heath, A. C., Scherrer, J. F., Xian, H., Lin, N., Eisen, S. A., Lyons, M. J., Goldberg, J. & Tsuang, M. T., Aug 20 1999, In: American Journal of Medical Genetics - Neuropsychiatric Genetics. 88, 4, p. 391-397 7 p.

Research output: Contribution to journal › Article › peer-review

115 Scopus citations

Intoxication after an Acute Dose of Alcohol: An Assessment of Its Association with Alcohol Consumption Patterns By using Twin Data

Heath, A. C. & Martin, N. G., Feb 1991, In: Alcoholism: Clinical and Experimental Research. 15, 1, p. 122-128 7 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Investigating the association between childhood sexual abuse and alcohol use disorders in women: Does It matter how we ask about sexual abuse?

Sartor, C. E., Mccutcheon, V. V., Nelson, E. C., Duncan, A. E., Bucholz, K. K. & Heath, A. C., 2012, In: Journal of Studies on Alcohol and Drugs. 73, 5, p. 740-748 9 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Is Alcohol‐Related Flushing a Protective Factor for Alcoholism in Caucasians?

Slutske, W. S., Heath, A. C., Madden, P. A. F., Bucholz, K. K., Dinwiddie, S. H., Dunne, M. P., Statham, D. S., Whitfield, J. B. & Martin, N. G., Jun 1995, In: Alcoholism: Clinical and Experimental Research. 19, 3, p. 582-592 11 p.

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Is the relationship between binge eating episodes and personality attributable to genetic factors?

Koren, R., Munn-Chernoff, M. A., Duncan, A. E., Bucholz, K. K., Madden, P. A. F., Heath, A. C. & Agrawal, A., Apr 2014, In: Twin Research and Human Genetics. 17, 2, p. 65-71 7 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Feb 5 2015, In: American journal of human genetics. 96, 2, p. 283-294 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

156 Scopus citations

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

Schumann, G., Liu, C., O'Reilly, P., Gao, H., Song, P., Xu, B., Ruggeri, B., Amin, N., Jia, T., Preis, S., Lepe, M. S., Akira, S., Barbieri, C., Baumeister, S., Cauchi, S., Clarke, T. K., Enroth, S., Fischer, K., Hällfors, J., Harris, S. E., & 107 othersHieber, S., Hofer, E., Hottenga, J. J., Johansson, Å., Joshi, P. K., Kaartinen, N., Laitinen, J., Lemaitre, R., Loukola, A., Luan, J., Lyytikäinen, L. P., Mangino, M., Manichaikul, A., Mbarek, H., Milaneschi, Y., Moayyeri, A., Mukamal, K., Nelson, C., Nettleton, J., Partinen, E., Rawal, R., Robino, A., Rose, L., Sala, C., Satoh, T., Schmidt, R., Schraut, K., Scott, R., Smith, A. V., Starr, J. M., Teumer, A., Trompet, S., Uitterlinden, A. G., Venturini, C., Vergnaud, A. C., Verweij, N., Vitart, V., Vuckovic, D., Wedenoja, J., Yengo, L., Yu, B., Zhang, W., Zhao, J. H., Boomsma, D. I., Chambers, J., Chasman, D. I., Daniela, T., De Geus, E., Deary, I., Eriksson, J. G., Esko, T., Eulenburg, V., Franco, O. H., Froguel, P., Gieger, C., Grabe, H. J., Gudnason, V., Gyllensten, U., Harris, T. B., Hartikainen, A. L., Heath, A. C., Hocking, L., Hofman, A., Huth, C., Jarvelin, M. R., Jukema, J. W., Kaprio, J., Kooner, J. S., Kutalik, Z., Lahti, J., Langenberg, C., Lehtimäki, T., Liu, Y., Madden, P. A. F., Martin, N., Morrison, A., Penninx, B., Pirastu, N., Psaty, B., Raitakari, O., Ridker, P., Rose, R., Rotter, J. I., Samani, N. J., Schmidt, H., Spector, T. D., Stott, D., Strachan, D., Tzoulaki, I., Van Der Harst, P., Van Duijn, C. M., Marques-Vidal, P., Vollenweider, P., Wareham, N. J., Whitfield, J. B., Wilson, J., Wolffenbuttel, B., Bakalkin, G., Evangelou, E., Liu, Y., Rice, K. M., Desrivières, S., Kliewer, S. A., Mangelsdorf, D. J., Müller, C. P., Levy, D. & Elliott, P., Dec 13 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. 14372-14377 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

149 Scopus citations

Lack of association of dopamine D4 receptor gene polymorphisms with ADHD subtypes in a population sample of twins

Todd, R. D., Neuman, R. J., Lobos, E. A., Jong, Y. J. I., Reich, W. & Heath, A. C., Jul 8 2001, In: American Journal of Medical Genetics - Neuropsychiatric Genetics. 105, 5, p. 432-438 7 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Latent class analysis of ADHD and comorbid symptoms in a population sample of adolescent female twins

Neuman, R. J., Heath, A., Reich, W., Bucholz, K. K., Madden, P. A. F., Sun, L., Todd, R. D. & Hudziak, J. J., 2001, In: Journal of Child Psychology and Psychiatry and Allied Disciplines. 42, 7, p. 933-942 10 p.

Research output: Contribution to journal › Article › peer-review

96 Scopus citations

Latent class analysis of child behavior checklist anxiety/depression in children and adolescents

Wadsworth, M. E., Hudziak, J. J., Heath, A. C. & Achenbach, T. M., 2001, In: Journal of the American Academy of Child and Adolescent Psychiatry. 40, 1, p. 106-114 9 p.

Research output: Contribution to journal › Article › peer-review

91 Scopus citations

Latent class analysis of child behavior checklist attention problems

Hudziak, J. J., Wadsworth, M. E., Heath, A. C. & Achenbach, T. M., 1999, In: Journal of the American Academy of Child and Adolescent Psychiatry. 38, 8, p. 985-991 7 p.

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Latent class and factor analysis of DSM-IV ADHD: A twin study of female adolescents

Hudziak, J. J., Heath, A. C., Madden, P. F., Reich, W., Bucholz, K. K., Slutske, W., Bierut, L. J., Neuman, R. J. & Todd, R. D., Aug 1998, In: Journal of the American Academy of Child and Adolescent Psychiatry. 37, 8, p. 848-857 10 p.

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Latent Class and Genetic Analysis Does Not Support Migraine with Aura and Migraine without Aura as Separate Entities

Nyholt, D. R., Gillespie, N. G., Heath, A. C., Merikangas, K. R., Duffy, D. L. & Martin, N. G., Apr 2004, In: Genetic Epidemiology. 26, 3, p. 231-244 14 p.

Research output: Contribution to journal › Article › peer-review

95 Scopus citations

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

on behalf of the Psychiatric Genomics Consortium Substance Use Disorders Workgroup, Aug 1 2020, In: Molecular Psychiatry. 25, 8, p. 1673-1687 15 p.

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Limitations of DSM-IV operationalizations of alcohol abuse and dependence in a sample of Australian twins

Lynskey, M. T., Nelson, E. C., Neuman, R. J., Bucholz, K. K., Madden, P. A. F., Knopik, V. S., Slutske, W., Whitfield, J. B., Martin, N. G. & Heath, A. C., Dec 2005, In: Twin Research and Human Genetics. 8, 6, p. 574-584 11 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Linkage analysis of alcohol dependence symptoms in the community.

Hansell, N. K., Agrawal, A., Whitfield, J. B., Morley, K. I., Gordon, S. D., Lind, P. A., Pergadia, M. L., Montgomery, G. W., Madden, P. A. F., Todd, R. D., Heath, A. C. & Martin, N. G., Jan 2010, In: Alcoholism, clinical and experimental research. 34, 1, p. 158-163 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Andrew Heath

Research output

Search results