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Personal profile

Research interests

Dr. Spec’s research is in fungal infections, particularly in immunocompromised patients, including those with transplants. His research focuses on Cryptococcus, Histoplasma, Candida, Aspergillus and other invasive molds. He studies the epidemiology and factors that affect outcomes in patients infected with fungus, both in the United States and globally in resource limited settings of Guatemala and Ethiopia. He serves as the Associate Director of our Infectious Disease Clinical Research Unit (ID-CRU) and is actively involved in the Mycoses Study Group (MSG), through which he participates and runs multicenter studies focused on new diagnostic tests and treatments for invasive fungal infections, and is the creator and leader of the Washington University Mycoses Group (a consortium of researchers interested in fungal infections). Dr. Spec also runs the division’s clinic focusing on invasive fungal infections, where he takes care of both immunocompromised and immunocompetent patients with fungal infections, which he considers the best and most rewarding part of his job.

Keywords

  • COVID-19

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Research Output

A multicenter, longitudinal cohort study of cryptococcosis in human immunodeficiency virus-negative people in the United States

Marr, K. A., Sun, Y., Spec, A., Lu, N., Panackal, A., Bennett, J., Pappas, P., Ostrander, D., Datta, K., Zhang, S. X. & Williamson, P. R., Jan 15 2020, In : Clinical Infectious Diseases. 70, 2, p. 252-261 10 p.

Research output: Contribution to journalArticle

  • 8 Scopus citations

    Hope on the horizon: Novel fungal treatments in development

    Rauseo, A. M., Coler-Reilly, A., Larson, L. & Spec, A., Jan 1 2020, In : Open Forum Infectious Diseases. 7, 2, ofaa016.

    Research output: Contribution to journalReview article

    Open Access
  • 11 Scopus citations

    Infectious disease consultation for candidaemia – Authors' reply

    Mejia-Chew, C., O'Halloran, J. A., Olsen, M. A., Stwalley, D., Salter, A., Powderly, W. G. & Spec, A., Feb 2020, In : The Lancet Infectious Diseases. 20, 2, p. 165-166 2 p.

    Research output: Contribution to journalLetter

    Open Access

    Potential missed opportunities for diagnosis of cryptococcosis and the association with mortality: A cohort study

    Salazar, A. S., Keller, M. R., Olsen, M. A., Nickel, K. B., George, I. A., Larson, L., Powderly, W. G. & Spec, A., Oct 2020, In : EClinicalMedicine. 27, 100563.

    Research output: Contribution to journalArticle

    Open Access