Andrei Vlassenko

2024

Accuracy of TrUE-Net in comparison to established white matter hyperintensity segmentation methods: An independent validation study

ADOPIC and ADNI Investigators, Jan 2024, In: NeuroImage. 285, 120494.

Research output: Contribution to journal › Article › peer-review

Open Access

EMATA: a toolbox for the automatic extraction and modeling of arterial inputs for tracer kinetic analysis in [¹⁸F]FDG brain studies

De Francisci, M., Silvestri, E., Bettinelli, A., Volpi, T., Goyal, M. S., Vlassenko, A. G., Cecchin, D. & Bertoldo, A., Dec 2024, In: EJNMMI Physics. 11, 1, 105.

Research output: Contribution to journal › Article › peer-review

Open Access

Individual-level metabolic connectivity from dynamic [¹⁸F]FDG PET reveals glioma-induced impairments in brain architecture and offers novel insights beyond the SUVR clinical standard

Vallini, G., Silvestri, E., Volpi, T., Lee, J., Vlassenko, A. G., Goyal, M., Cecchin, D., Corbetta, M. & Bertoldo, A., 2024, (Accepted/In press) In: European Journal of Nuclear Medicine and Molecular Imaging.

Research output: Contribution to journal › Article › peer-review

Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography - Computed Tomography Scanner

Lee, J., Metcalf, N., Durbin, T. A., Byers, J., Casey, K., Jafri, H., Goyal, M. & Vlassenko, A. G., Jun 7 2024, In: Journal of visualized experiments : JoVE. 208

Research output: Contribution to journal › Article › peer-review

The brain’s “dark energy” puzzle: How strongly is glucose metabolism linked to resting-state brain activity?

Volpi, T., Silvestri, E., Aiello, M., Lee, J. J., Vlassenko, A. G., Goyal, M. S., Corbetta, M. & Bertoldo, A., Aug 2024, In: Journal of Cerebral Blood Flow and Metabolism. 44, 8, p. 1433-1449 17 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2023

A new framework for metabolic connectivity mapping using bolus [¹⁸F]FDG PET and kinetic modeling

Volpi, T., Vallini, G., Silvestri, E., Francisci, M. D., Durbin, T., Corbetta, M., Lee, J. J., Vlassenko, A. G., Goyal, M. S. & Bertoldo, A., Nov 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 11, p. 1905-1918 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Brain aerobic glycolysis and resilience in Alzheimer disease

Goyal, M. S., Blazey, T., Metcalf, N. V., McAvoy, M. P., Strain, J. F., Rahmani, M., Durbin, T. J., Xiong, C., Benzinger, T. L. S., Morris, J. C., Raichle, M. E. & Vlassenko, A. G., Feb 14 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 7, e2212256120.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Investigating Tau and Amyloid Tracer Skull Binding in Studies of Alzheimer Disease

Flores, S., Chen, C. D., Su, Y., Dincer, A., Keefe, S. J., McKay, N. S., Paulick, A. M., Perez-Carrillo, G. G., Wang, L., Hornbeck, R. C., Goyal, M., Vlassenko, A., Schwarz, S., Nickels, M. L., Wong, D. F., Tu, Z., McConathy, J. E., Morris, J. C., Benzinger, T. L. S. & Gordon, B. A., Feb 1 2023, In: Journal of Nuclear Medicine. 64, 2

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

2022

Increased white matter glycolysis in humans with cerebral small vessel disease

Brier, M. R., Blazey, T., Raichle, M. E., Morris, J., Benzinger, T. L. S., Vlassenko, A. G., Snyder, A. & Goyal, M., Nov 2022, In: Nature Aging. 2, 11, p. 991-999 9 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2020

Comparison of the Ekblom-Bak Submaximal Test to a Maximal Test in a Cohort of Healthy Younger and Older Adults in the United States

Schultz, S. A., Byers, J., Benzinger, T. L. S., Reeds, D., Vlassenko, A. G., Cade, W. T. & Goyal, M. S., Nov 6 2020, In: Frontiers in Physiology. 11, 550285.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Spatiotemporal relationship between subthreshold amyloid accumulation and aerobic glycolysis in the human brain

Goyal, M. S., Gordon, B. A., Couture, L. E., Flores, S., Xiong, C., Morris, J. C., Raichle, M. E., L-S. Benzinger, T. & Vlassenko, A. G., Dec 2020, In: Neurobiology of Aging. 96, p. 165-175 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

2019

Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies

Su, Y., Flores, S., Wang, G., Hornbeck, R. C., Speidel, B., Joseph-Mathurin, N., Vlassenko, A. G., Gordon, B. A., Koeppe, R. A., Klunk, W. E., Jack, C. R., Farlow, M. R., Salloway, S., Snider, B. J., Berman, S. B., Roberson, E. D., Brosch, J., Jimenez-Velazques, I., van Dyck, C. H. & Galasko, D. & 25 others, Yuan, S. H., Jayadev, S., Honig, L. S., Gauthier, S., Hsiung, G. Y. R., Masellis, M., Brooks, W. S., Fulham, M., Clarnette, R., Masters, C. L., Wallon, D., Hannequin, D., Dubois, B., Pariente, J., Sanchez-Valle, R., Mummery, C., Ringman, J. M., Bottlaender, M., Klein, G., Milosavljevic-Ristic, S., McDade, E., Xiong, C., Morris, J. C., Bateman, R. J. & Benzinger, T. L. S., Dec 2019, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 180-190 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

95 Scopus citations

Persistent metabolic youth in the aging female brain

Goyal, M. S., Blazey, T. M., Su, Y., Couture, L. E., Durbin, T. J., Bateman, R. J., Benzinger, T. L. S., Morris, J. C., Raichle, M. E. & Vlassenko, A. G., Feb 19 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 8, p. 3251-3255 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

121 Scopus citations

2018

Aerobic glycolysis and tau deposition in preclinical Alzheimer's disease

Vlassenko, A. G., Gordon, B. A., Goyal, M. S., Su, Y., Blazey, T. M., Durbin, T. J., Couture, L. E., Christensen, J. J., Jafri, H., Morris, J. C., Raichle, M. E. & Benzinger, T. L. S., Jul 2018, In: Neurobiology of Aging. 67, p. 95-98 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

66 Scopus citations

A systematic meta-analysis of oxygen-toglucose and oxygen-to-carbohydrate ratios in the resting human brain

Blazey, T., Snyder, A. Z., Goyal, M. S., Vlassenko, A. G. & Raichle, M. E., Sep 2018, In: PloS one. 13, 9, e0204242.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Utility of perfusion PET measures to assess neuronal injury in Alzheimer's disease

Dominantly Inherited Alzheimer Network, Jan 1 2018, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 669-677 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Utilizing the Centiloid scale in cross-sectional and longitudinal PiB PET studies

Su, Y., Flores, S., Hornbeck, R. C., Speidel, B., Vlassenko, A. G., Gordon, B. A., Koeppe, R. A., Klunk, W. E., Xiong, C., Morris, J. C. & Benzinger, T. L. S., 2018, In: NeuroImage: Clinical. 19, p. 406-416 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

83 Scopus citations

2017

In vivo detection of microstructural correlates of brain pathology in preclinical and early Alzheimer Disease with magnetic resonance imaging

Zhao, Y., Wen, J., Benzinger, T. L., Vlassenko, A. G., Luo, J., Christensen, J. J. & Yablonskiy, D. A., Mar 1 2017, In: NeuroImage. 148, p. 296-304 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Loss of Brain Aerobic Glycolysis in Normal Human Aging

Goyal, M. S., Vlassenko, A. G., Blazey, T. M., Su, Y., Couture, L. E., Durbin, T. J., Bateman, R. J., Benzinger, T. L. S., Morris, J. C. & Raichle, M. E., Aug 1 2017, In: Cell metabolism. 26, 2, p. 353-360.e3

Research output: Contribution to journal › Article › peer-review

Open Access

206 Scopus citations

Quantitative hemodynamic PET imaging using image-derived arterial input function and a PET/MR hybrid scanner

Su, Y., Vlassenko, A. G., Couture, L. E., Benzinger, T. L. S., Snyder, A. Z., Derdeyn, C. P. & Raichle, M. E., 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 4, p. 1435-1446 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

2016

Brain aerobic glycolysis and motor adaptation learning

Shannon, B. J., Vaishnavi, S. N., Vlassenko, A. G., Shimony, J. S., Rutlin, J. & Raichle, M. E., Jun 28 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 26, p. E3782-E3791

Research output: Contribution to journal › Article › peer-review

Open Access

58 Scopus citations

Imaging and cerebrospinal fluid biomarkers in early preclinical alzheimer disease

Vlassenko, A. G., McCue, L., Jasielec, M. S., Su, Y., Gordon, B. A., Xiong, C., Holtzman, D. M., Benzinger, T. L. S., Morris, J. C. & Fagan, A. M., Sep 1 2016, In: Annals of neurology. 80, 3, p. 379-387 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

82 Scopus citations

Local and distributed PiB accumulation associated with development of preclinical Alzheimer's disease

Brier, M. R., McCarthy, J. E., Benzinger, T. L. S., Stern, A., Su, Y., Friedrichsen, K. A., Morris, J. C., Ances, B. M. & Vlassenko, A. G., 2016, In: Neurobiology of Aging. 38, p. 104-111 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

2015

Aerobic Glycolysis as a Marker of Tumor Aggressiveness: Preliminary Data in High Grade Human Brain Tumors

Vlassenko, A. G., McConathy, J., Couture, L. E., Su, Y., Massoumzadeh, P., Leeds, H. S., Chicoine, M. R., Tran, D. D., Huang, J., Dahiya, S., Marcus, D. S., Fouke, S. J., Rich, K. M., Raichle, M. E. & Benzinger, T. L. S., 2015, In: Disease Markers. 2015, 874904.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Longitudinal cerebrospinal fluid biomarker changes in preclinical Alzheimer disease during middle age

Sutphen, C. L., Jasielec, M. S., Shah, A. R., Macy, E. M., Xiong, C., Vlassenko, A. G., Benzinger, T. L. S., Stoops, E. E. J., Vanderstichele, H. M. J., Brix, B., Darby, H. D., Vandijck, M. L. J., Ladenson, J. H., Morris, J. C., Holtzman, D. M. & Fagan, A. M., Sep 1 2015, In: JAMA Neurology. 72, 9, p. 1029-1042 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

243 Scopus citations

2013

Low-frequency repetitive transcranial magnetic stimulation to the temporoparietal junction for tinnitus: Four-week stimulation trial

Piccirillo, J. F., Kallogjeri, D., Nicklaus, J., Wineland, A., Spitznagel, E. L., Vlassenko, A. G., Benzinger, T., Mathews, J. & Garcia, K. S., Apr 2013, In: JAMA Otolaryngology - Head and Neck Surgery. 139, 4, p. 388-395 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

Morning-evening variation in human brain metabolism and memory circuits

Shannon, B. J., Dosenbach, R. A., Su, Y., Vlassenko, A. G., Larson-Prior, L. J., Nolan, T. S., Snyder, A. Z. & Raichle, M. E., 2013, In: Journal of neurophysiology. 109, 5, p. 1444-1456 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

81 Scopus citations

Noninvasive estimation of the arterial input function in positron emission tomography imaging of cerebral blood flow

Su, Y., Arbelaez, A. M., Benzinger, T. L. S., Snyder, A. Z., Vlassenko, A. G., Mintun, M. A. & Raichle, M. E., Jan 2013, In: Journal of Cerebral Blood Flow and Metabolism. 33, 1, p. 115-121 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

Quantitative analysis of PiB-PET with FreeSurfer ROIs

Su, Y., D'Angelo, G. M., Vlassenko, A. G., Zhou, G., Snyder, A. Z., Marcus, D. S., Blazey, T. M., Christensen, J. J., Vora, S., Morris, J. C., Mintun, M. A. & Benzinger, T. L. S., Nov 6 2013, In: PloS one. 8, 11, e73377.

Research output: Contribution to journal › Article › peer-review

Open Access

183 Scopus citations

2011

Amyloid-beta plaque growth in cognitively normal adults: Longitudinal [ ¹¹C]Pittsburgh compound B data

Vlassenko, A. G., Mintun, M. A., Xiong, C., Sheline, Y. I., Goate, A. M., Benzinger, T. L. S. & Morris, J. C., Nov 2011, In: Annals of neurology. 70, 5, p. 857-861 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

129 Scopus citations

Low-frequency repetitive transcranial magnetic stimulation to the temporoparietal junction for tinnitus

Piccirillo, J. F., Garcia, K. S., Nicklaus, J., Pierce, K., Burton, H., Vlassenko, A. G., Mintun, M., Duddy, D., Kallogjeri, D. & Spitznagel, E. L., Mar 2011, In: Archives of Otolaryngology - Head and Neck Surgery. 137, 3, p. 221-228 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

56 Scopus citations

2010

Regional aerobic glycolysis in the human brain

Vaishnavi, S. N., Vlassenko, A. G., Rundle, M. M., Snyder, A. Z., Mintun, M. A. & Raichle, M. E., Oct 12 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 41, p. 17757-17762 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

511 Scopus citations

Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ) deposition

Vlassenko, A. G., Vaishnavi, S. N., Couture, L., Sacco, D., Shannon, B. J., Mach, R. H., Morris, J. C., Raichle, M. E. & Mintun, M. A., Oct 12 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 41, p. 17763-17767 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

332 Scopus citations

2006

Human brain glucose metabolism may evolve during activation: Findings from a modified FDG PET paradigm

Vlassenko, A. G., Rundle, M. M. & Mintun, M. A., Dec 2006, In: NeuroImage. 33, 4, p. 1036-1041 6 p.

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Regulation of blood flow in activated human brain by cytosolic NADH/NAD⁺ ratio

Vlassenko, A. G., Rundle, M. M., Raichle, M. E. & Mintun, M. A., Feb 15 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 6, p. 1964-1969 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

64 Scopus citations

2004

Cerebral perfusion response to successful treatment of depression with different serotoninergic agents

Vlassenko, A., Sheline, Y. I., Fischer, K. & Mintun, M. A., 2004, In: Journal of Neuropsychiatry and Clinical Neurosciences. 16, 3, p. 360-363 4 p.

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Decreased hippocampal 5-HT_2A receptor binding in major depressive disorder: In vivo measurement with [¹⁸F]altanserin positron emission tomography

Mintun, M. A., Sheline, Y. I., Moerlein, S. M., Vlassenko, A. G., Huang, Y. & Snyder, A. Z., Feb 1 2004, In: Biological Psychiatry. 55, 3, p. 217-224 8 p.

Research output: Contribution to journal › Article › peer-review

148 Scopus citations

Increased lactate/pyruvate ratio augments blood flow in physiologically activated human brain

Mintun, M. A., Vlassenko, A. G., Rundle, M. M. & Raichle, M. E., Jan 13 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 2, p. 659-664 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

118 Scopus citations

2002

Time-related increase of oxygen utilization in continuously activated human visual cortex

Mintun, M. A., Vlassenko, A. G., Shulman, G. L. & Snyder, A. Z., 2002, In: NeuroImage. 16, 2, p. 531-537 7 p.

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

2001

Blood flow and oxygen delivery to human brain during functional activity: Theoretical modeling and experimental data

Mintun, M. A., Lundstrom, B. N., Snyder, A. Z., Vlassenko, A. G., Shulman, G. L. & Raichle, M. E., Jun 5 2001, In: Proceedings of the National Academy of Sciences of the United States of America. 98, 12, p. 6859-6864 6 p.

Research output: Contribution to journal › Article › peer-review

298 Scopus citations

2000

Evaluation of early response to SU101 target-based therapy in patients with recurrent supratentorial malignant gliomas using FDG PET and Gd-DTPA MRI

Vlassenko, A. G., Thiessen, B., Beattie, B. J., Malkin, M. G. & Blasberg, R. G., 2000, In: Journal of Neuro-Oncology. 46, 3, p. 249-259 11 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

1999

Clinical syndromes and changes of cerebral hemodynamics and metabolism in subcortical stroke

Vlasenko, A. G., Konovalova, E. V. & Kadykov, A. S., 1999, In: Zhurnal Nevrologii i Psihiatrii imeni S.S. Korsakova. 99, 11, p. 51-54 4 p.

Research output: Contribution to journal › Article › peer-review

1997

Comparative quantitation of cerebral blood volume: SPECT versus PET

Vlasenko, A., Petit-Taboué, M. C., Bouvard, G., Morello, R. & Derlon, J. M., Jun 1997, In: Journal of Nuclear Medicine. 38, 6, p. 919-924 6 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

1993

Effektivnost' khirurgicheskogo lecheniia okkliuziruiushchikh porazheniǐ sonnykh arteriǐ.

Translated title of the contribution: The efficacy of the surgical treatment of occlusive lesions of the carotid arteriesSpiridonov, A. A., Kuperberg, E. B., Iarustovskiǐ, M. B., Rudnev, I. N., Kutsenko, G. B., Gaǐdashev, A. E., Vlasenko, A. G. & Tutova, M. G., 1993, In: Grudnaya i Serdechno-Sosudistaya Khirurgiya. 2, p. 3-8 6 p.

Research output: Contribution to journal › Article › peer-review

1992

Assessment of cerebrovascular reactivity with low doses of nitroglycerin: Transcranial doppler and cerebral blood flow

Borisenko, V. V. & Vlasenko, A. G., 1992, In: Cerebrovascular Diseases. 2, 1, p. 58-60 3 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

1987

Izmeneniia v psikhoémotsional'noǐ sfere i ikh korrektsiia pri nevralgii troǐnichnogo nerva.

Translated title of the contribution: Changes in the psychoemotional sphere and their correction in trigeminal neuralgiaKarlov, V. A., Megdiatova, R. S. & Vlasenko, A. G., 1987, In: Sovetskaya Meditsina. 8, p. 30-32 3 p.

Research output: Contribution to journal › Article › peer-review

Andrei Vlassenko

Research output

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