Research output per year
Research output per year
Personal profile
Research interests
The main research focus is aging and neurodegenerative disorders. Specific research interests include evaluating regulation and functional reserve of brain blood flow and metabolism using positron emission tomography in cognitively normal aging and neurodegenerative disorders; establishing metabolic markers of preclinical state of Alzheimer’s disease; identifying longitudinal patterns of beta-amyloid accumulation in preclinical and clinically manifested Alzheimer’s disease; evaluating the relationship between brain metabolism and beta-amyloid deposition and their potential contribution to optimization of treatment strategies in Alzheimer’s disease.
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Collaborations and top research areas from the last five years
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Accuracy of TrUE-Net in comparison to established white matter hyperintensity segmentation methods: An independent validation study
ADOPIC and ADNI Investigators, Jan 2024, In: NeuroImage. 285, 120494.Research output: Contribution to journal › Article › peer-review
Open Access -
Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography - Computed Tomography Scanner
Lee, J., Metcalf, N., Durbin, T. A., Byers, J., Casey, K., Jafri, H., Goyal, M. & Vlassenko, A. G., Jun 7 2024, In: Journal of visualized experiments : JoVE. 208Research output: Contribution to journal › Article › peer-review
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The brain’s “dark energy” puzzle: How strongly is glucose metabolism linked to resting-state brain activity?
Volpi, T., Silvestri, E., Aiello, M., Lee, J. J., Vlassenko, A. G., Goyal, M. S., Corbetta, M. & Bertoldo, A., Aug 2024, In: Journal of Cerebral Blood Flow and Metabolism. 44, 8, p. 1433-1449 17 p.Research output: Contribution to journal › Article › peer-review
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A new framework for metabolic connectivity mapping using bolus [18F]FDG PET and kinetic modeling
Volpi, T., Vallini, G., Silvestri, E., Francisci, M. D., Durbin, T., Corbetta, M., Lee, J. J., Vlassenko, A. G., Goyal, M. S. & Bertoldo, A., Nov 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 11, p. 1905-1918 14 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Brain aerobic glycolysis and resilience in Alzheimer disease
Goyal, M. S., Blazey, T., Metcalf, N. V., McAvoy, M. P., Strain, J. F., Rahmani, M., Durbin, T. J., Xiong, C., Benzinger, T. L. S., Morris, J. C., Raichle, M. E. & Vlassenko, A. G., Feb 14 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 7, e2212256120.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations