Research output per year
Research output per year
- 23 results
Search results
-
2023
Acute Kidney Injury-Induced Circulating TNFR1/2 Elevations Correlate with Persistent Kidney Injury and Progression to Fibrosis
Arthanarisami, A., Komaru, Y., Katsouridi, C., Schumacher, J., Verges, D. K., Ning, L., Abdelmageed, M. M., Herrlich, A. & Kefaloyianni, E., Sep 2023, In: Cells. 12, 18, 2214.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
TNF or EGFR inhibition equally block AKI-to-CKD transition: opportunities for etanercept treatment
Abdelmageed, M. M., Kefaloyianni, E., Arthanarisami, A., Komaru, Y., Atkinson, J. J. & Herrlich, A., May 1 2023, In: Nephrology Dialysis Transplantation. 38, 5, p. 1139-1150 12 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
2022
Identification of kidney injury–released circulating osteopontin as causal agent of respiratory failure
Khamissi, F. Z., Ning, L., Kefaloyianni, E., Dun, H., Arthanarisami, A., Keller, A., Atkinson, J. J., Li, W., Wong, B., Dietmann, S., Lavine, K., Kreisel, D. & Herrlich, A., Feb 2022, In: Science Advances. 8, 8, eabm5900.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
2019
FOXM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury
Chang-Panesso, M., Kadyrov, F. F., Lalli, M., Wu, H., Ikeda, S., Kefaloyianni, E., Abdelmageed, M. M., Herrlich, A., Kobayashi, A. & Humphreys, B. D., Dec 2 2019, In: Journal of Clinical Investigation. 129, 12, p. 5501-5517 17 p.Research output: Contribution to journal › Article › peer-review
Open Access115 Scopus citations -
Proximal tubule-derived amphiregulin amplifies and integrates profibrotic EGF receptor signals in kidney fibrosis
Kefaloyianni, E., Raja, M. R. K., Schumacher, J., Muthu, M. L., Krishnadoss, V., Waikar, S. S. & Herrlich, A., 2019, In: Journal of the American Society of Nephrology. 30, 12, p. 2370-2383 14 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
2018
Functional genomics approach identifies novel signaling regulators of TGFα ectodomain shedding
Wilson, J. L., Kefaloyianni, E., Stopfer, L., Harrison, C., Sabbisetti, V. S., Fraenkel, E., Lauffenburger, D. A. & Herrlich, A., Jan 2018, In: Molecular Cancer Research. 16, 1, p. 147-161 15 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2016
ADAM17 substrate release in proximal tubule drives kidney fibrosis
Kefaloyianni, E., Muthu, M. L., Kaeppler, J., Sun, X., Sabbisetti, V., Chalaris, A., Rose-John, S., Wong, E., Sagi, I., Waikar, S. S., Rennke, H., Humphreys, B. D., Bonventre, J. V. & Herrlich, A., Aug 18 2016, In: JCI Insight. 1, 13, e87023.Research output: Contribution to journal › Article › peer-review
Open Access103 Scopus citations -
Growth factor and co-receptor release by structural regulation of substrate metalloprotease accessibility
Parra, L. M., Hartmann, M., Schubach, S., Ma, J., Herrlich, P. & Herrlich, A., Nov 23 2016, In: Scientific reports. 6, 37464.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2015
Distinct intracellular domain substrate modifications selectively regulate ectodomain cleavage of NRG1 or CD44
Parra, L. M., Hartmann, M., Schubach, S., Li, Y., Herrlich, P. & Herrlich, A., 2015, In: Molecular and cellular biology. 35, 19, p. 3381-3395 15 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Inside-out regulation of ectodomain cleavage of cluster-of-differentiation-44 (CD44) and of neuregulin-1 requires substrate dimerization
Hartmann, M., Parra, L. M., Ruschel, A., Lindner, C., Morrison, H., Herrlich, A. & Herrlich, P., Jul 10 2015, In: Journal of Biological Chemistry. 290, 28, p. 17041-17054 14 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
PI3kα and STAT1 interplay regulates human mesenchymal stem cell immune polarization
Mounayar, M., Kefaloyianni, E., Smith, B., Solhjou, Z., Maarouf, O. H., Azzi, J., Chabtini, L., Fiorina, P., Kraus, M., Briddell, R., Fodor, W., Herrlich, A. & Abdi, R., Jun 1 2015, In: STEM CELLS. 33, 6, p. 1892-1901 10 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Tumor suppressor NF2 blocks cellular migration by inhibiting ectodomain cleavage of CD44
Hartmann, M., Parra, L. M., Ruschel, A., Bohme, S., Li, Y., Morrison, H., Herrlich, A. & Herrlich, P., May 1 2015, In: Molecular Cancer Research. 13, 5, p. 879-890 12 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
2014
Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC
Zhang, K., Jones, L., Lim, S., Maher, C. A., Adkins, D., Lewis, J., Kimple, R. J., Fertig, E. J., Chung, C. H., Van Tine, B. A., Ellis, M. J., Herrlich, A. & Michel, L. S., 2014, In: Oncotarget. 5, 19, p. 9281-9294 14 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
2013
Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways
Dang, M., Armbruster, N., Miller, M. A., Cermeno, E., Hartmann, M., Bell, G. W., Root, D. E., Lauffenburger, D. A., Lodish, H. F. & Herrlich, A., Jun 11 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 24, p. 9776-9781 6 p.Research output: Contribution to journal › Article › peer-review
Open Access70 Scopus citations -
2011
Epidermal Growth Factor (EGF) ligand release by substrate-specific A disintegrin and metalloproteases (ADAMs) involves different protein kinase C (PKC) isoenzymes depending on the stimulus
Dang, M., Dubbin, K., D'Aiello, A., Hartmann, M., Lodish, H. & Herrlich, A., May 20 2011, In: Journal of Biological Chemistry. 286, 20, p. 17704-17713 10 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities
Miller, M. A., Barkal, L., Jeng, K., Herrlich, A., Moss, M., Griffith, L. G. & Lauffenburger, D. A., Apr 2011, In: Integrative Biology. 3, 4, p. 422-438 17 p.Research output: Contribution to journal › Article › peer-review
Open Access80 Scopus citations -
2008
Ectodomain cleavage of the EGF ligands HB-EGF, neuregulin1-β, and TGF-α is specifically triggered by different stimuli and involves different PKC isoenzymes
Herrlich, A., Klinman, E., Fu, J., Sadegh, C. & Lodish, H., Dec 2008, In: FASEB Journal. 22, 12, p. 4281-4295 15 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
2004
Role of proneuregulin 1 cleavage and human epidermal growth factor receptor activation in hypertonic aquaporin induction
Herrlich, A., Leitch, V. & King, L. S., Nov 2 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 44, p. 15799-15804 6 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
2000
Epidermal growth factor receptor tyro sine kinase mediates Ras activation by gonadotropin-releasing hormone
Grosse, R., Roelle, S., Herrlich, A., Höhn, J. & Gudermann, T., Apr 21 2000, In: Journal of Biological Chemistry. 275, 16, p. 12251-12260 10 p.Research output: Contribution to journal › Article › peer-review
Open Access63 Scopus citations -
Gonadotropin-releasing hormone receptor initiates multiple signaling pathways by exclusively coupling to G(q/11) proteins
Grosse, R., Schmid, A., Schöneberg, T., Herrlich, A., Muhn, P., Schultz, G. & Gudermann, T., Mar 31 2000, In: Journal of Biological Chemistry. 275, 13, p. 9193-9200 8 p.Research output: Contribution to journal › Article › peer-review
Open Access138 Scopus citations -
1998
Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells
Herrlich, A., Daub, H., Knebel, A., Herrlich, P., Ullrich, A., Schultz, G. & Gudermann, T., Jul 21 1998, In: Proceedings of the National Academy of Sciences of the United States of America. 95, 15, p. 8985-8990 6 p.Research output: Contribution to journal › Article › peer-review
Open Access137 Scopus citations -
1997
Signal characteristics of G protein-transactivated EGF receptor
Daub, H., Wallasch, C., Lankenau, A., Herrlich, A. & Ullrich, A., Dec 1 1997, In: EMBO Journal. 16, 23, p. 7032-7044 13 p.Research output: Contribution to journal › Article › peer-review
Open Access597 Scopus citations -
1996
Involvement of G(s) and G(i) proteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C
Herrlich, A., Kühn, B., Grosse, R., Schmid, A., Schultz, G. & Gudermann, T., 1996, In: Journal of Biological Chemistry. 271, 28, p. 16764-16772 9 p.Research output: Contribution to journal › Article › peer-review
Open Access128 Scopus citations