• 1377 Citations

Research output per year

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Personal profile

Research interests

The Herrlich laboratory's primary expertise lies in the study of regulation of cytokine release by ectodomain cleavage and of its cell biological, physiological and pathophysiological consequences. We study regulation of ectodomain cleavage in vitro using various approaches, and also its relevance in human disease, in particular kidney disease and cancer.

Areas of Clinical Interest

Acute kidney failure, chronic kidney failure

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Research Output

  • 1377 Citations
  • 19 Article
  • 2 Review article
  • 1 Editorial

FOXM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury

Chang-Panesso, M., Kadyrov, F. F., Lalli, M., Wu, H., Ikeda, S., Kefaloyianni, E., Abdelmageed, M. M., Herrlich, A., Kobayashi, A. & Humphreys, B. D., Dec 2 2019, In : Journal of Clinical Investigation. 129, 12, p. 5501-5517 17 p.

Research output: Contribution to journalArticle

Open Access
  • 14 Scopus citations

    Proximal tubule-derived amphiregulin amplifies and integrates profibrotic EGF receptor signals in kidney fibrosis

    Kefaloyianni, E., Raja, M. R. K., Schumacher, J., Muthu, M. L., Krishnadoss, V., Waikar, S. S. & Herrlich, A., Jan 1 2019, In : Journal of the American Society of Nephrology. 30, 12, p. 2370-2383 14 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations

    Functional genomics approach identifies novel signaling regulators of TGFα ectodomain shedding

    Wilson, J. L., Kefaloyianni, E., Stopfer, L., Harrison, C., Sabbisetti, V. S., Fraenkel, E., Lauffenburger, D. A. & Herrlich, A., Jan 2018, In : Molecular Cancer Research. 16, 1, p. 147-161 15 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    ADAM Metalloprotease-Released Cancer Biomarkers

    Herrlich, P. & Herrlich, A., Jul 2017, In : Trends in Cancer. 3, 7, p. 482-490 9 p.

    Research output: Contribution to journalReview article

  • 5 Scopus citations