Research output per year
Research output per year
Personal profile
Research interests
The Herrlich laboratory's primary expertise lies in the study of regulation of cytokine release by ectodomain cleavage and of its cell biological, physiological and pathophysiological consequences. We study regulation of ectodomain cleavage in vitro using various approaches, and also its relevance in human disease, in particular kidney disease and cancer.
Areas of Clinical Interest
Acute kidney failure, chronic kidney failure
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FOXM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury
Chang-Panesso, M., Kadyrov, F. F., Lalli, M., Wu, H., Ikeda, S., Kefaloyianni, E., Abdelmageed, M. M., Herrlich, A., Kobayashi, A. & Humphreys, B. D., Dec 2 2019, In: Journal of Clinical Investigation. 129, 12, p. 5501-5517 17 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Proximal tubule-derived amphiregulin amplifies and integrates profibrotic EGF receptor signals in kidney fibrosis
Kefaloyianni, E., Raja, M. R. K., Schumacher, J., Muthu, M. L., Krishnadoss, V., Waikar, S. S. & Herrlich, A., 2019, In: Journal of the American Society of Nephrology. 30, 12, p. 2370-2383 14 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Functional genomics approach identifies novel signaling regulators of TGFα ectodomain shedding
Wilson, J. L., Kefaloyianni, E., Stopfer, L., Harrison, C., Sabbisetti, V. S., Fraenkel, E., Lauffenburger, D. A. & Herrlich, A., Jan 2018, In: Molecular Cancer Research. 16, 1, p. 147-161 15 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
iRhoms: A Potential Path to More Specific Therapeutic Targeting of Lupus Nephritis
Herrlich, A. & Kefaloyianni, E., Oct 2018, In: American Journal of Kidney Diseases. 72, 4, p. 617-619 3 p.Research output: Contribution to journal › Editorial
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ADAM Metalloprotease-Released Cancer Biomarkers
Herrlich, P. & Herrlich, A., Jul 2017, In: Trends in Cancer. 3, 7, p. 482-490 9 p.Research output: Contribution to journal › Review article › peer-review
8 Scopus citations