Personal profile

Research interests

My main research interests are the physical principles and molecular mechanisms determining biomolecular function. A particular focus are intrinsically disordered proteins (IDPs). At variance with the classical structurefunction paradigm that we are familiar with from 50 years of structural biology, IDPs lack a persistent structure but, nevertheless, participate in many biological processes such as transcription, translation and signal transduction. In my work, I combine fluorescence single-molecule spectroscopy with concepts from polymer physics to explain fundamental properties of IDPs. I am interested in expanding the scope of single-molecule and correlation methods to investigate the role of disordered proteins in vivo, especially within RNA granules, non-membrane bound organelles that play a key-role in the spatial and temporal regulation of RNA, and whose malfunctioning has been linked to infertilities, cancer, and neurodegenerative diseases. A long-term goal will be to bridge the gap between detailed molecular understanding and cellular and organismic processes.


In our lab we promote an inclusive environment that is safe and supportive, where every question can be asked, and every idea can be heard. We believe that obstacles are better overcome together, discoveries are made to be shared, and diversity is what makes our contributions unique, yet essential for everyone else. We are committed to support trainees and scientists from all traditionally underrepresented groups in STEM and make academia an inclusive environment for everyone.

Available to Mentor:

  • PhD/MSTP Students


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Collaborations and top research areas from the last five years

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