Amy Armstrong

2025

Efficacy and safety of entrectinib in children with extracranial solid or central nervous system (CNS) tumours harbouring NTRK or ROS1 fusions

Desai, A. V., Bagchi, A., Armstrong, A. E., van Tilburg, C. M., Basu, E. M., Robinson, G. W., Wang, H., Casanova, M., André, N., Campbell-Hewson, Q., Wu, Y., Cardenas, A., Ci, B., Ryklansky, C., Devlin, C. E., Meneses-Lorente, G., Wulff, J., Hutchinson, K. E., Gajjar, A. & Fox, E., May 2 2025, In: European Journal of Cancer. 220, 115308.

Research output: Contribution to journal › Article › peer-review

Open Access

Treatment of focal anaplastic Wilms tumor: A report from the Children's Oncology Group AREN0321 and AREN03B2 studies

the Children's Oncology Group AREN0321 and AREN03B2 Study Committees, Jan 15 2025, In: Cancer. 131, 2, e35713.

Research output: Contribution to journal › Article › peer-review

Yolk Sac Tumor of the Liver: An Important Differential for Liver Mass with Elevated Serum Alpha-Fetoprotein in the Pediatric Population

He, M., Hoerschgen, K., Armstrong, A. E., Zhang, L., Dillon, P., White, F. & Dehner, L. P., 2025, In: Fetal and Pediatric Pathology. 44, 2, p. 98-105 8 p.

Research output: Contribution to journal › Article › peer-review

2024

Consensus recommendations for systemic therapies in the management of relapsed Ewing sarcoma: A report from the National Ewing Sarcoma Tumor Board

Gupta, A., Dietz, M. S., Riedel, R. F., Dhir, A., Borinstein, S. C., Isakoff, M. S., Aye, J. M., Rainusso, N., Armstrong, A. E., DuBois, S. G., Wagner, L. M., Rosenblum, J. M., Cohen-Gogo, S., Albert, C. M., Zahler, S., Chugh, R. & Trucco, M., Dec 1 2024, In: Cancer. 130, 23, p. 4028-4039 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Early Detection of Malignant and Premalignant Peripheral Nerve Tumors Using Cell-Free DNA Fragmentomics

Sundby, R. T., Szymanski, J. J., Pan, A. C., Jones, P. A., Mahmood, S. Z., Reid, O. H., Srihari, D., Armstrong, A. E., Chamberlain, S., Burgic, S., Weekley, K., Murray, B., Patel, S., Qaium, F., Lucas, A. N., Fagan, M., Dufek, A., Meyer, C. F., Collins, N. B. & Pratilas, C. A. & 9 others, Dombi, E., Gross, A. M., Kim, A. R., Chrisinger, J. S. A., Dehner, C. A., Widemann, B. C., Hirbe, A. C., Chaudhuri, A. A. & Shern, J. F., Oct 1 2024, In: Clinical Cancer Research. 30, 19, p. 4363-4376 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Prospective External Validation of the Esbenshade Vanderbilt Models Accurately Predicts Bloodstream Infection Risk in Febrile Non-Neutropenic Children With Cancer

Zhao, Z., Patel, P. A., Slatnick, L., Sitthi-Amorn, A., Bielamowicz, K. J., Nunez, F. A., Walsh, A. M., Hess, J., Rossoff, J., Elgarten, C., Myers, R., Saab, R., Basbous, M., Mccormick, M., Aftandilian, C., Richards, R., Nessle, C. N., Tribble, A. C., Sheth Bhutada, J. K. & Coven, S. L. & 21 others, Runco, D., Wilkes, J., Gurunathan, A., Guinipero, T., Belsky, J. A., Lee, K., Wong, V., Malhotra, M., Armstrong, A., Jerkins, L. P., Cross, S. J., Fisher, L., Stein, M. T., Wu, N. L., Yi, T., Orgel, E., Haeusler, G. M., Wolf, J., Demedis, J. M., Miller, T. P. & Esbenshade, A. J., Mar 1 2024, In: Journal of Clinical Oncology. 42, 7, p. 832-841 10 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2023

Advances in the clinical management of high-risk Wilms tumors

Ortiz, M. V., Koenig, C., Armstrong, A. E., Brok, J., de Camargo, B., Mavinkurve-Groothuis, A. M. C., Herrera, T. B. V., Venkatramani, R., Woods, A. D., Dome, J. S. & Spreafico, F., Mar 2023, In: Pediatric Blood and Cancer. 70, 3, e30153.

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Advances in the clinical management of high-risk Wilms tumors

Ortiz, M. V., Koenig, C., Armstrong, A. E., Brok, J., de Camargo, B., Mavinkurve-Groothuis, A. M. C., Herrera, T. B. V., Venkatramani, R., Woods, A. D., Dome, J. S. & Spreafico, F., May 2023, In: Pediatric Blood and Cancer. 70, S2, e30342.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Scopus citations

Lorlatinib use in an infant with thalamic ALK-positive histiocytosis

Eldem, I., Picarsic, J., Kumar, A., Mossé, Y. P., Roberts, K. F., Armstrong, A. E. & Sisk, B. A., Sep 2023, In: Pediatric Blood and Cancer. 70, 9, e30378.

Research output: Contribution to journal › Letter › peer-review

2 Scopus citations

Loss of Chromosome 3q Is a Prognostic Marker in Fusion-Negative Rhabdomyosarcoma

Dehner, C. A., Bell, R. C., Cao, Y., He, K., Chrisinger, J. S. A., Armstrong, A. E., Yohe, M., Shern, J. & Hirbe, A. C., 2023, In: JCO Precision Oncology. 7, e2300037.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Sclerosing Epithelioid Fibrosarcoma of the Liver in a Pediatric Patient

Armstrong, A., Boulos, F., Kulkarni, S., Stoll, J., Doyle, M. B. M., Khan, A. & He, M., Mar 1 2023, In: Pediatric and Developmental Pathology. 26, 2, p. 153-160 8 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Sustained Response with Dose-reduced Selpercatinib in a Pediatric Patient with Metastatic NCOA4-RET Fusion Papillary Thyroid Carcinoma

Suydam, A. C., Bach, A., Markovina, S., Grigsby, P., Sprague, J. & Armstrong, A. E., Nov 1 2023, In: Journal of Pediatric Hematology/Oncology. 45, 8, p. E984-E987

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Treatment decisions and the use of MEK inhibitors for children with neurofibromatosis type 1-related plexiform neurofibromas

Armstrong, A. E., Belzberg, A. J., Crawford, J. R., Hirbe, A. C. & Wang, Z. J., Dec 2023, In: BMC Cancer. 23, 1, 553.

Research output: Contribution to journal › Review article › peer-review

Open Access

21 Scopus citations

2022

A Systematic Review of Recent and Ongoing Clinical Trials in Patients With the Neurofibromatoses

Acar, S., Nieblas-Bedolla, E., Armstrong, A. E. & Hirbe, A. C., Sep 2022, In: Pediatric Neurology. 134, p. 1-6 6 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

7 Scopus citations

Entrectinib in children and young adults with solid or p y g,, aberrations (STARTRK-NG)

Desai, A. V., Robinson, G. W., Gauvain, K., Basu, E. M., Macy, M. E., Maese, L., Whipple, N. S., Sabnis, A. J., Foster, J. H., Shusterman, S., Yoon, J., Weiss, B. D., Abdelbaki, M. S., Armstrong, A. E., Cash, T., Pratilas, C. A., Corradini, N., Marshall, L. V., Farid-Kapadia, M. & Chohan, S. & 9 others, Devlin, C., Meneses-Lorente, G., Cardenas, A., Hutchinson, K. E., Bergthold, G., Caron, H., Maneval, E. C., Gajjar, A. & Fox, E., Oct 1 2022, In: Neuro-oncology. 24, 10, p. 1776-1789 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

Plexiform neurofibroma: shedding light on the investigational agents in clinical trials

Acar, S., Armstrong, A. E. & Hirbe, A. C., 2022, In: Expert Opinion on Investigational Drugs. 31, 1, p. 31-40 10 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2021

Cabozantinib for neurofibromatosis type 1–related plexiform neurofibromas: a phase 2 trial

Neurofibromatosis Clinical Trials Consortium, Jan 2021, In: Nature medicine. 27, 1, p. 165-173 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

Cutaneous reactions to pediatric cancer treatment: Part I. Conventional chemotherapy

Sous, D., Armstrong, A. E., Huang, J. T., Shah, S., Carlberg, V. M. & Coughlin, C. C., Jan 1 2021, In: Pediatric Dermatology. 38, 1, p. 8-17 10 p.

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Genetic characterization, current model systems and prognostic stratification in pax fusion-negative vs. Pax fusion-positive rhabdomyosarcoma

Dehner, C. A., Armstrong, A. E., Yohe, M., Shern, J. F. & Hirbe, A. C., Oct 2021, In: Genes. 12, 10, 1500.

Research output: Contribution to journal › Review article › peer-review

Open Access

17 Scopus citations

2020

Early administration of imatinib mesylate reduces plexiform neurofibroma tumor burden with durable results after drug discontinuation in a mouse model of neurofibromatosis type 1

Armstrong, A. E., Rhodes, S. D., Smith, A., Chen, S., Bessler, W., Ferguson, M. J., Jiang, L., Li, X., Yuan, J., Yang, X., Yang, F. C., Robertson, K. A., Ingram, D. A., Blakeley, J. O. & Clapp, D. W., Aug 1 2020, In: Pediatric Blood and Cancer. 67, 8, e28372.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Neurofibromatosis type 1-related tumours in paediatrics: an evolving treatment landscape

Armstrong, A. E., Brossier, N. M. & Hirbe, A. C., Jul 2020, In: The Lancet Child and Adolescent Health. 4, 7, p. 488-490 3 p.

Research output: Contribution to journal › Comment/debate

6 Scopus citations

2019

5-Hydroxymethylcytosine profiles are prognostic of outcome in neuroblastoma and reveal transcriptional networks that correlate with tumor phenotype

Applebaum, M. A., Barr, E. K., Karpus, J., Nie, J., Zhang, Z., Armstrong, A. E., Uppal, S., Sukhanova, M., Zhang, W., Chlenski, A., Salwen, H. R., Wilkinson, E., Dobratic, M., Grossman, R., Godley, L. A., Stranger, B. E., He, C. & Cohn, S. L., 2019, In: JCO Precision Oncology. 3, p. 1-12 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Cdkn2a (Arf) loss drives NF1-associated atypical neurofibroma and malignant transformation

Rhodes, S. D., He, Y., Smith, A., Jiang, L., Lu, Q., Mund, J., Li, X., Bessler, W., Qian, S., Dyer, W., Sandusky, G. E., Horvai, A. E., Armstrong, A. E. & Clapp, D. W., Aug 15 2019, In: Human molecular genetics. 28, 16, p. 2752-2762 11 p.

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Cell-free DNA next-generation sequencing successfully detects infectious pathogens in pediatric oncology and hematopoietic stem cell transplant patients at risk for invasive fungal disease

Armstrong, A. E., Rossoff, J., Hollemon, D., Hong, D. K., Muller, W. J. & Chaudhury, S., Jul 2019, In: Pediatric Blood and Cancer. 66, 7, e27734.

Research output: Contribution to journal › Article › peer-review

Open Access

81 Scopus citations

Noninvasive diagnosis of infection using plasma next-generation sequencing: A single-center experience

Rossoff, J., Chaudhury, S., Soneji, M., Patel, S. J., Kwon, S., Armstrong, A. & Muller, W. J., Jun 3 2019, In: Open Forum Infectious Diseases. 6, 8, ofz327.

Research output: Contribution to journal › Article › peer-review

Open Access

102 Scopus citations

Prolonged response to sorafenib in a patient with refractory metastatic osteosarcoma and a somatic PDGFRA D846V mutation

Armstrong, A. E., Walterhouse, D. O., Leavey, P. J., Reichek, J. & Walz, A. L., Jan 2019, In: Pediatric Blood and Cancer. 66, 1, e27493.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

2018

A unique subset of low-risk wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A children’s oncology group study

Armstrong, A. E., Gadd, S., Huff, V., Gerhard, D. S., Dome, J. S. & Perlman, E. J., Dec 2018, In: PloS one. 13, 12, e0208936.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Current Knowledge and Practice of Pediatric Providers in Umbilical Cord Blood Banking

Armstrong, A. E., Fonstad, R., Spellman, S., Tullius, Z. & Chaudhury, S., Feb 1 2018, In: Clinical Pediatrics. 57, 2, p. 161-167 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Late Effects in Pediatric High-risk Neuroblastoma Survivors after Intensive Induction Chemotherapy Followed by Myeloablative Consolidation Chemotherapy and Triple Autologous Stem Cell Transplants

Armstrong, A. E., Danner-Koptik, K., Golden, S., Schneiderman, J., Kletzel, M., Reichek, J. & Gosiengfiao, Y., 2018, In: Journal of Pediatric Hematology/Oncology. 40, 1, p. 31-35 5 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Proximal hypospadias and a novel WT1 variant: When should genetic testing be considered?

Dabrowski, E., Armstrong, A. E., Leeth, E., Johnson, E., Cheng, E., Gosiengfiao, Y. & Finlayson, C., Apr 2018, In: Pediatrics. 141, p. S491-S495

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

2017

A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor

Gadd, S., Huff, V., Walz, A. L., Ooms, A. H. A. G., Armstrong, A. E., Gerhard, D. S., Smith, M. A., Guidry Auvil, J. M., Meerzaman, D., Chen, Q. R., Hsu, C. H., Yan, C., Nguyen, C., Hu, Y., Hermida, L. C., Davidsen, T., Gesuwan, P., Ma, Y., Zong, Z. & Mungall, A. J. & 11 others, Moore, R. A., Marra, M. A., Dome, J. S., Mullighan, C. G., Ma, J., Wheeler, D. A., Hampton, O. A., Ross, N., Gastier-Foster, J. M., Arold, S. T. & Perlman, E. J., Oct 1 2017, In: Nature Genetics. 49, 10, p. 1487-1494 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

259 Scopus citations

The impact of high-resolution HLA-A, HLA-B, HLA-C, and HLA-DRB1 on transplant-related outcomes in single-unit umbilical cord blood transplantation in pediatric patients

Armstrong, A. E., Smyth, E., Helenowski, I. B., Tse, W. T., Duerst, R. E., Schneiderman, J., Kletzel, M. & Chaudhury, S., Jan 1 2017, In: Journal of Pediatric Hematology/Oncology. 39, 1, p. 26-32 7 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2015

Treatment of neuroblastoma in congenital central hypoventilation syndrome with a PHOX2B polyalanine repeat expansion mutation: New twist on a neurocristopathy syndrome

Armstrong, A. E., Weese-Mayer, D. E., Mian, A., Maris, J. M., Batra, V., Gosiengfiao, Y., Reichek, J., Madonna, M. B., Bush, J. W., Shore, R. M. & Walterhouse, D. O., Nov 1 2015, In: Pediatric Blood and Cancer. 62, 11, p. 2007-2010 4 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

2014

Irinotecan and temozolomide for treatment of neuroblastoma in a patient with renal failure on hemodialysis

Armstrong, A. E., Dargart, J., Reichek, J., Walterhouse, D. O., Matossian, D., Cohn, R. A. & Gosiengfiao, Y., May 2014, In: Pediatric Blood and Cancer. 61, 5, p. 949-950 2 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

2012

Giant cell tumor of rib arising anteriorly as a large inframammary mass: A case report and review of the literature

Sharma, A. & Armstrong, A. E., 2012, In: Case Reports in Medicine. 2012, 850509.

Research output: Contribution to journal › Review article › peer-review

Open Access

10 Scopus citations

Graft-versus-host disease after solid organ transplantation: A single center experience and review of literature

Sharma, A., Armstrong, A. E., Posner, M. P., Kimball, P. M., Cotterell, A. H., King, A. L., Fisher, R. A. & Godder, K., 2012, In: Annals of Transplantation. 17, 4, p. 133-139 7 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

2011

Peptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells

Saccoccio, F. M., Sauer, A. L., Cui, X., Armstrong, A. E., Habib, E. S. E., Johnson, D. C., Ryckman, B. J., Klingelhutz, A. J., Adler, S. P. & McVoy, M. A., Mar 24 2011, In: Vaccine. 29, 15, p. 2705-2711 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Amy Armstrong

Research output

Search results