Research output per year
Research output per year
Personal profile
Research interests
Our research focuses on unraveling the molecular mechanisms underlying substrate specificity and degradation by AAA proteolytic machines and their associated adaptor proteins, utilizing structural biology, biochemistry, and cellular assays in both bacteria and human mitochondria.
Available to Mentor:
- PhD/MSTP Students
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Dive into the research topics where Alireza Ghanbarpour is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Regulation of Absorption and Emission in a Protein/Fluorophore Complex
Santos, E. M., Chandra, I., Assar, Z., Sheng, W., Ghanbarpour, A., Bingham, C., Vasileiou, C., Geiger, J. H. & Borhan, B., Aug 16 2024, In: ACS Chemical Biology. 19, 8, p. 1725-1732 8 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A closed translocation channel in the substrate-free AAA+ ClpXP protease diminishes rogue degradation
Ghanbarpour, A., Cohen, S. E., Fei, X., Kinman, L. F., Bell, T. A., Zhang, J. J., Baker, T. A., Davis, J. H. & Sauer, R. T., Dec 2023, In: Nature communications. 14, 1, 7281.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
The SspB adaptor drives structural changes in the AAA+ ClpXP protease during ssrA-tagged substrate delivery
Ghanbarpour, A., Fei, X., Baker, T. A., Davis, J. H. & Sauer, R. T., Feb 7 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 6, e2219044120.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Advances in X-ray crystallography methods to study structural dynamics of macromolecules
Kermani, A. A., Aggarwal, S. & Ghanbarpour, A., Jan 1 2022, Advanced Spectroscopic Methods to Study Biomolecular Structure and Dynamics. Elsevier, p. 309-355 47 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
10 Scopus citations -
A structural explanation for the mechanism and specificity of plant branching enzymes I and IIb
Gavgani, H. N., Fawaz, R., Ehyaei, N., Walls, D., Pawlowski, K., Fulgos, R., Park, S., Assar, Z., Ghanbarpour, A. & Geiger, J. H., Jan 1 2022, In: Journal of Biological Chemistry. 298, 1, 101395.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations