I study enteric bacterial pathogens and pathogen-driven changes in the intestine. Specifically, my research focuses on studying the pathogenesis of enterotoxigenic E. coli (ETEC) infections, their interactions with host, and host responses. My research aims are to better understand ETEC-host interactions at the intestinal epithelial interface to enhance our understanding of the damaging effects of ETEC infections and associated sequelae, including malnutrition and poor growth, affecting millions of children in low-middle income countries. I use intestinal stem cell-driven organoid as well as an infant mouse model to 1) investigate factors that facilitate ETEC-host interactions and 2) determine the impacts of ETEC enterotoxins on intestinal epithelial homeostasis, structure, and function.