Alan Schwartz

Research Output

Research Output per year

1970 2020

• 15387 Citations
• 202 Article
• 24 Review article
• 3 Comment/debate
• 3 Editorial
• 3 More
  • 2 Letter
  • 1 Conference article

Research Output per year

Research Output per year

Search results

• 2020

  Accuracy of electromyometrial imaging of uterine contractions in clinical environment

  Wang, H., Wu, W., Talcott, M., McKinstry, R. C., Woodard, P. K., Macones, G. A., Schwartz, A. L., Cuculich, P., Cahill, A. G. & Wang, Y., Jan 2020, In: Computers in Biology and Medicine. 116, 103543.

  Research output: Contribution to journal › Article › peer-review

  • Uterine Contraction
  • Electromyography
  • Noise
  • Imaging techniques
  • Uterus
  4 Scopus citations

• Electromyometrial imaging dataset of electromyograms and isochrone maps under deformation/electrical noise contaminations

  Wang, H., Wu, W., Talcott, M., McKinstry, R. C., Woodard, P. K., Macones, G. A., Schwartz, A. L., Cuculich, P., Cahill, A. G. & Wang, Y., Feb 2020, In: Data in Brief. 28, 105078.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Contamination
  • Imaging techniques
  • Electrophysiology
  • Magnetic resonance
  • Geometry
• 2019

  Noninvasive high-resolution electromyometrial imaging of uterine contractions in a translational sheep model

  Wu, W., Wang, H., Zhao, P., Talcott, M., Lai, S., Mckinstry, R. C., Woodard, P. K., Macones, G. A., Schwartz, A. L., Cahill, A. G., Cuculich, P. S. & Wang, Y., 2019, In: Science translational medicine. 11, 483, eaau1428.

  Research output: Contribution to journal › Article › peer-review

  • Uterine Contraction
  • Sheep
  • Electrodes
  • Three-Dimensional Imaging
  • Electromyography
  7 Scopus citations
• 2018

  RNA-Seq identifies genes whose proteins are transformative in the differentiation of cytotrophoblast to syncytiotrophoblast, in human primary villous and BeWo trophoblasts

  Azar, C., Valentine, M., Trausch-Azar, J., Druley, T., Nelson, D. M. & Schwartz, A. L., Dec 1 2018, In: Scientific reports. 8, 1, 5142.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Trophoblasts
  • RNA
  • Proteins
  • Placentation
  • Gene Expression
  10 Scopus citations
• 2016

  RNF4-Dependent Oncogene Activation by Protein Stabilization

  Thomas, J. J., Abed, M., Heuberger, J., Novak, R., Zohar, Y., Beltran Lopez, A. P., Trausch-Azar, J. S., Ilagan, M. X. G., Benhamou, D., Dittmar, G., Kopan, R., Birchmeier, W., Schwartz, A. L. & Orian, A., Sep 20 2016, In: Cell Reports. 16, 12, p. 3388-3400 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oncogene Proteins
  • Ubiquitination
  • Chemical activation
  • Stabilization
  • Phosphorylation
  22 Scopus citations
• 2015

  Isoform-Specific SCF^Fbw7 ubiquitination mediates differential regulation of PGC-1α

  Trausch-Azar, J. S., Abed, M., Orian, A. & Schwartz, A. L., Apr 1 2015, In: Journal of Cellular Physiology. 230, 4, p. 842-852 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ubiquitination
  • Ubiquitin
  • Protein Isoforms
  • Degradation
  • Ubiquitin-Protein Ligases
  22 Scopus citations
• 2010

  Ubiquitin proteasome-dependent degradation of the transcriptional coactivator PGC-1α via the N-terminal pathway

  Trausch-Azar, J., Leone, T. C., Kelly, D. P. & Schwartz, A. L., Dec 17 2010, In: Journal of Biological Chemistry. 285, 51, p. 40192-40200 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteasome Endopeptidase Complex
  • Ubiquitin
  • Degradation
  • Metabolic Networks and Pathways
  • Organelle Biogenesis
  52 Scopus citations
• 2009

  Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9

  Song, H., Li, Y., Lee, J., Schwartz, A. L. & Bu, G., Feb 1 2009, In: Cancer research. 69, 3, p. 879-886 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Low Density Lipoprotein Receptor-Related Protein-1
  • Lipoprotein Receptors
  • Matrix Metalloproteinase 2
  • Matrix Metalloproteinase 9
  • Cell Movement
  118 Scopus citations
• 2008

  Glucocorticoids differentially regulate degradation of MyoD and Id1 by N-terminal ubiquitination to promote muscle protein catabolism

  Sun, L., Trausch-Azar, J. S., Muglia, L. J. & Schwartz, A. L., Mar 4 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 9, p. 3339-3344 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Muscle Proteins
  • Ubiquitination
  • MyoD Protein
  • Glucocorticoids
  • Proteolysis
  38 Scopus citations

• In vivo interactions of MyoD, Id1, and E2A proteins determined by acceptor photobleaching fluorescence resonance energy transfer

  Lingbeck, J. M., Trausch-Azar, J. S., Ciechanover, A. & Schwartz, A. L., Jun 1 2008, In: FASEB Journal. 22, 6, p. 1694-1701 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Photobleaching
  • MyoD Protein
  • Forster resonance energy transfer
  • Fluorescence Resonance Energy Transfer
  • Proteins
  6 Scopus citations

• The N-terminal domain of MyoD is necessary and sufficient for its nuclear localization-dependent degradation by the ubiquitin system

  Sadeh, R., Breitschopf, K., Bercovich, B., Zoabi, M., Kravtsova-Ivantsiv, Y., Kornitzer, D., Schwartz, A. & Ciechanover, A., Oct 14 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 41, p. 15690-15695 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ubiquitin
  • Lysine
  • Ubiquitination
  • Protein Transport
  • Tumor Suppressor Protein p14ARF
  18 Scopus citations
• 2007

  E2A protein degradation by the ubiquitin-proteasome system is stage-dependent during muscle differentiation

  Sun, L., Trausch-Azar, J. S., Ciechanover, A. & Schwartz, A. L., Jan 18 2007, In: Oncogene. 26, 3, p. 441-448 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteasome Endopeptidase Complex
  • Ubiquitin
  • Proteolysis
  • Muscles
  • Myoblasts
  13 Scopus citations

• Slow endocytosis of the LDL receptor-related protein 1B: Implications for a novel cytoplasmic tail conformation

  Knisely, J. M., Li, Y., Griffith, J. M., Geuze, H. J., Schwartz, A. L. & Bu, G., Sep 10 2007, In: Experimental Cell Research. 313, 15, p. 3298-3307 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Low Density Lipoprotein Receptor-Related Protein-1
  • Endocytosis
  • Mutation
  8 Scopus citations
• 2005

  E12 and E47 modulate cellular localization and proteasome-mediated degradation of MyoD and Id1

  Lingbeck, J. M., Trausch-Azar, J. S., Ciechanover, A. & Schwartz, A. L., Sep 22 2005, In: Oncogene. 24, 42, p. 6376-6384 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteasome Endopeptidase Complex
  • Ubiquitin
  • Muscles
  • Half-Life
  • Proteins
  41 Scopus citations

• Independent and cooperative roles of N-glycans and molecular chaperones in the folding and disulfide bond formation of the low-density lipoprotein (LDL) receptor-related protein

  McCormick, L. M., Urade, R., Arakaki, Y., Schwartz, A. L. & Bu, G., Apr 19 2005, In: Biochemistry. 44, 15, p. 5794-5803 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Glycosylation
  • LDL-Receptor Related Proteins
  • Lipoprotein Receptors
  • Molecular Chaperones
  • LDL Receptors
  15 Scopus citations

• Ubiquitin-proteasome-mediated degradation, intracellular localization, and protein synthesis of MyoD and Id1 during muscle differentiation

  Sun, L., Trausch-Azar, J. S., Ciechanover, A. & Schwartz, A. L., Jul 15 2005, In: Journal of Biological Chemistry. 280, 28, p. 26448-26456 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • MyoD Protein
  • Proteasome Endopeptidase Complex
  • Ubiquitin
  • Muscle
  • Myoblasts
  41 Scopus citations
• 2004

  Degradation of the Id2 developmental regulator: Targeting via N-terminal ubiquitination

  Fajerman, I., Schwartz, A. L. & Ciechanover, A., Feb 6 2004, In: Biochemical and Biophysical Research Communications. 314, 2, p. 505-512 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ubiquitination
  • Ubiquitin
  • Degradation
  • Proteasome Endopeptidase Complex
  • Proteins
  56 Scopus citations

• Degradation of the LDL receptor class 2 mutants is mediated by a proteasome-dependent pathway

  Li, Y., Lu, W., Schwartz, A. L. & Bu, G., Jun 2004, In: Journal of lipid research. 45, 6, p. 1084-1091 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • LDL Receptors
  • Proteasome Endopeptidase Complex
  • Degradation
  • Proteasome Inhibitors
  • Cricetulus
  21 Scopus citations

• LRP6 expression promotes cancer cell proliferation and tumorigenesis by altering β-catenin subcellular distribution

  Li, Y., Lu, W., He, X., Schwartz, A. L. & Bu, G., Dec 2 2004, In: Oncogene. 23, 56, p. 9129-9135 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Low Density Lipoprotein Receptor-Related Protein-1
  • Catenins
  • Carcinogenesis
  • Cell Proliferation
  • Wnt Signaling Pathway
  64 Scopus citations

• The tumor suppressor protein p16^INK4a and the human papillomavirus oncoprotein-58 E7 are naturally occurring lysine-less proteins that are degraded by the ubiquitin system: Direct evidence for ubiquitination at the N-terminal residue

  Ben-Saadon, R., Fajerman, I., Ziv, T., Hellman, U., Schwartz, A. L. & Ciechanover, A., Oct 1 2004, In: Journal of Biological Chemistry. 279, 40, p. 41414-41421 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Tumor Suppressor Proteins
  • Oncogene Proteins
  • Ubiquitination
  • Ubiquitin
  • Lysine
  93 Scopus citations

• Ubiquitin-proteasome-mediated degradation of Id1 is modulated by MyoD

  Traasch-Azar, J. S., Lingbeck, J., Ciechanover, A. & Schwartz, A. L., Jul 30 2004, In: Journal of Biological Chemistry. 279, 31, p. 32614-32619 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteasome Endopeptidase Complex
  • Ubiquitin
  • Lysine
  • Degradation
  • Transfection
  42 Scopus citations
• 2003

  Determinants of nuclear and cytoplasmic ubiquitin-mediated degradation of MyoD

  Lingbeck, J. M., Trausch-Azar, J. S., Ciechanover, A. & Schwartz, A. L., Jan 17 2003, In: Journal of Biological Chemistry. 278, 3, p. 1817-1823 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ubiquitin
  • Lysine
  • Ubiquitination
  • Cytoplasm
  • Degradation
  45 Scopus citations
• 2002

  Cellular catabolism of lipid poor apolipoprotein E via cell surface LDL receptor-related protein

  Narita, M., Holtzman, D. M., Fagan, A. M., LaDu, M. J., Yu, L., Han, X., Gross, R. W., Bu, G. & Schwartz, A. L., Nov 1 2002, In: Journal of Biochemistry. 132, 5, p. 743-749 7 p.

  Research output: Contribution to journal › Article › peer-review

  • LDL-Receptor Related Proteins
  • LDL Receptors
  • Apolipoproteins E
  • Low Density Lipoprotein Receptor-Related Protein-1
  • Membrane Proteins
  39 Scopus citations

• Low density lipoprotein (LDL) receptor-related protein 1B impairs urokinase receptor regeneration on the cell surface and inhibits cell migration

  Li, Y., Knisely, J. M., Lu, W., McCormick, L. M., Wang, J., Henkin, J., Schwartz, A. L. & Bu, G., Nov 1 2002, In: Journal of Biological Chemistry. 277, 44, p. 42366-42371 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • LDL-Receptor Related Proteins
  • Low Density Lipoprotein Receptor-Related Protein-1
  • Urokinase Plasminogen Activator Receptors
  • LDL Receptors
  • Urokinase-Type Plasminogen Activator
  56 Scopus citations

• Proteasome regulates the delivery of LDL receptor-related protein into the degradation pathway

  Melman, L., Geuze, H. J., Li, Y., McCormick, L. M., Van Kerkhof, P., Strous, G. J., Schwartz, A. L. & Bu, G., Sep 2002, In: Molecular biology of the cell. 13, 9, p. 3325-3335 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Low Density Lipoprotein Receptor-Related Protein-1
  • Proteasome Endopeptidase Complex
  • Proteins
  • Endocytosis
  • LDL-Receptor Related Proteins
  37 Scopus citations

• Receptor-associated protein facilitates proper folding and maturation of the low-density lipoprotein receptor and its class 2 mutants

  Li, Y., Lu, W., Schwartz, A. L. & Bu, G., Apr 16 2002, In: Biochemistry. 41, 15, p. 4921-4928 8 p.

  Research output: Contribution to journal › Article › peer-review

  • LDL Receptors
  • Proteins
  • Hyperlipoproteinemia Type II
  • Molecular Chaperones
  • Endocytosis
  29 Scopus citations

• Ubiquitin-mediated degradation of cellular proteins in health and disease

  Ciechanover, A. & Schwartz, A. L., 2002, In: Hepatology. 35, 1, p. 3-6 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  63 Scopus citations
• 2001

  Dissection of receptor folding and ligand-binding property with functional minireceptors of LDL receptor-related protein

  Obermoeller-McCormick, L. M., Li, Y., Osaka, H., FitzGerald, D. J., Schwartz, A. L. & Bu, G., 2001, In: Journal of cell science. 114, 5, p. 899-908 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Low Density Lipoprotein Receptor-Related Protein-1
  • Dissection
  • Ligands
  • Pseudomonas aeruginosa toxA protein
  • Molecular Chaperones
  99 Scopus citations

• Mechanisms of ubiquitin-mediated, limited processing of the NF-κB1 precursor protein p105

  Ciechanover, A., Gonen, H., Bercovich, B., Cohen, S., Fajerman, I., Israël, A., Mercurio, F., Kahana, C., Schwartz, A. L., Iwai, K. & Orian, A., Jan 1 2001, In: Biochimie. 83, 3-4, p. 341-349 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Ankyrin Repeat
  • Protein Precursors
  • Phosphorylation
  • Ubiquitin
  • Ligases
  55 Scopus citations

• The Nuclear Ubiquitin-Proteasome System Degrades MyoD

  Floyd, Z. E., Trausch-Azar, J. S., Reinstein, E., Ciechanover, A. & Schwartz, A. L., Jun 22 2001, In: Journal of Biological Chemistry. 276, 25, p. 22468-22475 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteasome Endopeptidase Complex
  • Ubiquitin
  • Molecular mass
  • leptomycin B
  • Degradation
  60 Scopus citations

• The Putative Tumor Suppressor LRP1B, a Novel Member of the Low Density Lipoprotein (LDL) Receptor Family, Exhibits Both Overlapping and Distinct Properties with the LDL Receptor-related Protein

  Liu, C. X., Li, Y., Obermoeller-McCormick, L. M., Schwartz, A. L. & Bu, G., Aug 3 2001, In: Journal of Biological Chemistry. 276, 31, p. 28889-28896 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • LDL-Receptor Related Proteins
  • LDL Receptors
  • Tumors
  • Ligands
  • Genes
  86 Scopus citations
• 2000

  Degradation of the E7 human papillomavirus oncoprotein by the ubiquitin-proteasome system: Targeting via ubiquitination of the N-terminal residue

  Reinstein, E., Scheffner, M., Oren, M., Ciechanover, A. & Schwartz, A., Nov 30 2000, In: Oncogene. 19, 51, p. 5944-5950 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oncogene Proteins
  • Ubiquitination
  • Proteasome Endopeptidase Complex
  • Ubiquitin
  • Proteolysis
  144 Scopus citations

• Recombinant full-length tissue factor pathway inhibitor fails to bind to the cell surface: Implications for catabolism in vitro and in vivo

  Ho, G., Narita, M., Broze, G. J. & Schwartz, A. L., Mar 15 2000, In: Blood. 95, 6, p. 1973-1978 6 p.

  Research output: Contribution to journal › Article › peer-review

  • lipoprotein-associated coagulation inhibitor
  • In Vitro Techniques
  • Factor Xa
  • Low Density Lipoprotein Receptor-Related Protein-1
  • Pharmacokinetics
  15 Scopus citations

• SCF(β-TrCP) ubiquitin ligase-mediated processing of NF-κB p105 requires phosphorylation of its C-terminus by IκB kinase

  Orian, A., Gonen, H., Bercovich, B., Fajerman, I., Eytan, E., Israël, A., Mercurio, F., Iwai, K., Schwartz, A. L. & Ciechanover, A., Jun 1 2000, In: EMBO Journal. 19, 11, p. 2580-2591 12 p.

  Research output: Contribution to journal › Article › peer-review

  • SKP Cullin F-Box Protein Ligases
  • Phosphorylation
  • Ligases
  • Ubiquitin
  • Phosphotransferases
  137 Scopus citations
• 1999

  Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor

  Govers, R., Ten Broeke, T., Van Kerkhof, P., Schwartz, A. L. & Strous, G. J., Jan 4 1999, In: EMBO Journal. 18, 1, p. 28-36 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Somatotropin Receptors
  • Ubiquitin
  • Ligands
  • Endocytosis
  • Dimerization
  167 Scopus citations

• Structural motifs involved in ubiquitin-mediated processing of the NF- κB precursor p105: Roles of the Glycine-rich region and a downstream ubiquitination domain

  Orian, A., Schwartz, A. L., Israël, A., Whiteside, S., Kahana, C. & Ciechanover, A., May 1999, In: Molecular and cellular biology. 19, 5, p. 3664-3673 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ubiquitination
  • Glycine
  • Ubiquitin
  • ubiquitin precursor
  • ATP dependent 26S protease
  91 Scopus citations

• The carboxyl-terminal domain of receptor-associated protein facilitates proper folding and trafficking of the very low density lipoprotein receptor by interaction with the three amino-terminal ligand-binding repeats of the receptor

  Savonen, R., Obermoeller, L. M., Trausch-Azar, J. S., Schwartz, A. L. & Bu, G., Sep 3 1999, In: Journal of Biological Chemistry. 274, 36, p. 25877-25882 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • VLDL receptor
  • Ligands
  • Proteins
  • Terminal Repeat Sequences
  • LDL Receptors
  25 Scopus citations
• 1998

  Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway

  Gross-Mesilaty, S., Reinstein, E., Bercovich, B., Tobias, K. E., Schwartz, A. L., Kahana, C. & Ciechanover, A., Jul 7 1998, In: Proceedings of the National Academy of Sciences of the United States of America. 95, 14, p. 8058-8063 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oncogene Proteins
  • Ubiquitin
  • Proteolysis
  • lactacystin
  • Proteins
  186 Scopus citations

• Ca²⁺ and receptor-associated protein are independently required for proper folding and disulfide bond formation of the low density lipoprotein receptor-related protein

  Obermoeller, L. M., Ghen, Z., Schwartz, A. L. & Bu, G., Aug 28 1998, In: Journal of Biological Chemistry. 273, 35, p. 22374-22381 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • LDL-Receptor Related Proteins
  • Lipoprotein Receptors
  • LDL Receptors
  • Disulfides
  • Proteins
  36 Scopus citations

• Di-leucine-mediated internalization of ligand by a truncated growth hormone receptor is independent of the ubiquitin conjugation system

  Govers, R., Van Kerkhof, P., Schwartz, A. L. & Strous, G. J., Jun 26 1998, In: Journal of Biological Chemistry. 273, 26, p. 16426-16433 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Somatotropin Receptors
  • Leucine
  • Ubiquitin
  • Ligands
  • Dimerization
  44 Scopus citations

• Nerve growth factor induces rapid increases in functional cell surface low density lipoprotein receptor-related protein

  Bu, G., Sun, Y., Schwartz, A. L. & Holtzman, D. M., May 22 1998, In: Journal of Biological Chemistry. 273, 21, p. 13359-13365 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • LDL-Receptor Related Proteins
  • Lipoprotein Receptors
  • LDL Receptors
  • Nerve Growth Factor
  • Membrane Proteins
  58 Scopus citations

• The low-density lipoprotein receptor-related protein (LRP) mediates clearance of coagulation factor Xa in vivo

  Narita, M., Rudolph, A. E., Miletich, J. P. & Schwartz, A. L., Jan 15 1998, In: Blood. 91, 2, p. 555-560 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • LDL-Receptor Related Proteins
  • Factor Xa
  • LDL Receptors
  • Lipoprotein Receptors
  • Proteins
  37 Scopus citations
• 1997

  Adenovirus mediated gene transfer into rat lung grafts at the time of harvest

  Schmid, R. A., Narita, M., Boasquevisque, C. H., Ando, K., Botney, M. D., Cooper, J. D., Schwartz, A. L. & Patterson, G. A., Jun 1997, In: European Journal of Cardio-thoracic Surgery. 11, 6, p. 1023-1029 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adenoviridae
  • Transplants
  • Lung
  • Genes
  • Transfection
  5 Scopus citations

• Glypican-3 is a binding protein on the HepG2 cell surface for tissue factor pathway inhibitor

  Mast, A. E., Higuchi, D. A., Huang, Z. F., Warshawsky, I., Schwartz, A. L. & Broze, G. J., Oct 15 1997, In: Biochemical Journal. 327, 2, p. 577-583 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Glypicans
  • lipoprotein-associated coagulation inhibitor
  • Hep G2 Cells
  • Carrier Proteins
  • sodium chlorate
  56 Scopus citations

• Growth hormone-induced signal transduction depends on an intact ubiquitin system

  Strous, G. J., Van Kerkhof, P., Covers, R., Rotwein, P. & Schwartz, A. L., 1997, In: Journal of Biological Chemistry. 272, 1, p. 40-43 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Signal transduction
  • Somatotropin Receptors
  • Cricetulus
  • Ubiquitin
  • Growth Hormone
  55 Scopus citations

• Identification of a region within the ubiquitin-activating enzyme required for nuclear targeting and phosphorylation

  Stephen, A. G., Trausch-Azar, J. S., Handley-Gearhart, P. M., Ciechanover, A. & Schwartz, A. L., Apr 18 1997, In: Journal of Biological Chemistry. 272, 16, p. 10895-10903 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ubiquitin-Activating Enzymes
  • Phosphorylation
  • Serine
  • Epitopes
  • Electrophoresis
  25 Scopus citations

• Linkage of the ubiquitin-conjugating system and the endocytic pathway in ligand-induced internalization of the growth hormone receptor

  Govers, R., Van Kerkhof, P., Schwartz, A. L. & Strous, G. J., Aug 15 1997, In: EMBO Journal. 16, 16, p. 4851-4858 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Somatotropin Receptors
  • Ubiquitin
  • Ligands
  • Ubiquitination
  • Endocytosis
  91 Scopus citations

• Role of heparan sulfate proteoglycans in the uptake and degradation of tissue factor pathway inhibitor-coagulation factor Xa complexes

  Ho, G., Broze, G. J. & Schwartz, A. L., Jul 4 1997, In: Journal of Biological Chemistry. 272, 27, p. 16838-16844 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • lipoprotein-associated coagulation inhibitor
  • Heparan Sulfate Proteoglycans
  • Factor Xa
  • Degradation
  • Glycosaminoglycans
  52 Scopus citations

• The low-density lipoprotein receptor-related protein, a multifunctional apolipoprotein E receptor, modulates hippocampal neurite development

  Narita, M., Bu, G., Holtzman, D. M. & Schwartz, A. L., Feb 1997, In: Journal of Neurochemistry. 68, 2, p. 587-595 9 p.

  Research output: Contribution to journal › Article › peer-review

  • LDL-Receptor Related Proteins
  • Low Density Lipoprotein Receptor-Related Protein-1
  • LDL Receptors
  • Neurites
  • Lipoprotein Receptors
  91 Scopus citations

• Ubiquitin-dependent degradation of certain protein substrates in vitro requires the molecular chaperone Hsc70

  Bercovich, B., Stancovski, I., Mayer, A., Blumenfeld, N., Laszlo, A., Schwartz, A. L. & Ciechanover, A., Apr 4 1997, In: Journal of Biological Chemistry. 272, 14, p. 9002-9010 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Molecular Chaperones
  • Ubiquitin
  • Proteolysis
  • Substrates
  • Degradation
  241 Scopus citations