Personal profile
Research interests
Dr. Toriola’s research focuses on characterizing the molecular basis and determinants of mammographic breast density and breast cancer in order to identify those that can be targeted in breast cancer prevention, especially in premenopausal women. He is the Principal Investigator on 2 R01s (R37CA23560, R01CA246592) and an R21 (R21CA216515) on mammographic breast density. In addition to his NIH/NCI funded phase II clinical trial investigating the effect of RANKL inhibition on mammographic breast density and breast tissue/blood markers in premenopausal women with dense breasts (R37CA235602), he is also using state of the art metabolomics platforms to interrogate the metabolite profiles of mammographic breast density in premenopausal women (R01CA246592).
In addition, he performs molecular epidemiologic studies on colorectal and pancreatic cancers, evaluating the utility of biomarkers to investigate the associations of energetics and inflammation with risk/mortality. He is an MPI on the ColoCare Study (U01CA206110), a large multicenter cohort of colorectal cancer (CRC) patients for interdisciplinary studies of CRC prognosis and outcomes.
Available to Mentor:
- PhD Students
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Collaborations and top research areas from the last five years
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Association of Sleep Disturbance With Survival After Colorectal Cancer Diagnosis: Results From the ColoCare Study
Peoples, A. R., Damerell, V., Ose, J., Siegel, E. M., Lin, T., Hardikar, S., Himbert, C., Ilozumba, M. N., Schrotz-King, P., Crowder, S. L., Toriola, A. T., Shibata, D., Li, C. I., Byrd, D. A., Aßmann, E. S., Jim, H. S. L., Figueiredo, J. C., Ulrich, C. M. & Gigic, B., Feb 2026, In: Cancer medicine. 15, 2, e71576.Research output: Contribution to journal › Article › peer-review
Open Access -
Blood DNA methylation-predicted plasma protein levels and colorectal cancer survival
Richards, A. R., Gomez, M. F., Dowling, B. I., Jean-Baptiste, E., Gigic, B., Figueiredo, J. C., Li, C. I., Shibata, D., Toriola, A. T., Byrd, D. A., Ulrich, C. M., Stewart, P. A., Siegel, E. M. & Kresovich, J. K., Dec 2026, In: Clinical Epigenetics. 18, 1, 24.Research output: Contribution to journal › Article › peer-review
Open Access -
Demographic and Clinicopathologic Factors Associated With Colorectal Adenoma Recurrence
Awan, U. A., Song, Q., Ciombor, K. K., Toriola, A. T., Choi, J., Su, T., Shu, X. O., Idrees, K., Washington, K. M., Zheng, W., Wen, W., Yin, Z. & Guo, X., Feb 4 2026, In: JAMA Network Open. 9, 2, e2556853.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Scopus citations -
Generational trends in reproductive factors among women in the US: implications for breast cancer incidence
Yang, L. & Toriola, A. T., Dec 2026, In: Breast Cancer Research. 28, 1, 54.Research output: Contribution to journal › Article › peer-review
Open Access -
Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention
Li, Q., Song, Q., Chen, Z., Choi, J., Moreno, V., Ping, J., Wen, W., Li, C., Shu, X., Yan, J., Shu, X. O., Cai, Q., Long, J., Huyghe, J. R., Pai, R., Gruber, S. B., Yang, Y., Casey, G., Wang, X. & Toriola, A. T. & 11 others, , Jan 8 2026, In: American journal of human genetics. 113, 1, p. 41-56 16 p.Research output: Contribution to journal › Article › peer-review
Open Access