Research output per year
Research output per year
Personal profile
Research interests
My primary scientific interests are human genetic variation associated with complex neurological and psychiatric disease, in particular substance dependence, and the mechanisms of those associations. �My long-term career goal is to combine the power of genome-wide genetic association studies (GWAS) and bioinformatic tools, together with focused experimentally-derived functional data, to model the influence of variation in individual genes upon complex psychiatric phenotypes.
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Collaborations and top research areas from the last five years
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Research output
- 23 Article
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Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients
Bloom, A. J., Mao, X., Strickland, A., Sasaki, Y., Milbrandt, J. & DiAntonio, A., Dec 2022, In: Molecular neurodegeneration. 17, 1, 1.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy
Krus, K. L., Strickland, A., Yamada, Y., Devault, L., Schmidt, R. E., Bloom, A. J., Milbrandt, J. & DiAntonio, A., Jun 28 2022, In: Cell Reports. 39, 13, 111001.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss
Wu, T., Zhu, J., Strickland, A., Ko, K. W., Sasaki, Y., Dingwall, C. B., Yamada, Y., Figley, M. D., Mao, X., Neiner, A., Bloom, A. J., DiAntonio, A. & Milbrandt, J., Oct 19 2021, In: Cell Reports. 37, 3, 109872.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Mouse strain-specific acute respiratory effects of nicotine unrelated to nicotine metabolism
Bloom, A. J., Sep 2 2019, In: Toxicology Mechanisms and Methods. 29, 7, p. 542-548 7 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes
Bloom, A. J., Wang, P. F. & Kharasch, E. D., Apr 2019, In: Pharmacology Research and Perspectives. 7, 2, e00468.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations