Adam J. Bloom

Assistant Professor of Genetics, Assistant Professor of Anesthesiology

    • 390 Citations
    20072019

    Research output per year

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    Personal profile

    Research interests

    My primary scientific interests are human genetic variation associated with complex neurological and psychiatric disease, in particular substance dependence, and the mechanisms of those associations. �My long-term career goal is to combine the power of genome-wide genetic association studies (GWAS) and bioinformatic tools, together with focused experimentally-derived functional data, to model the influence of variation in individual genes upon complex psychiatric phenotypes.

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    Research Output

    • 390 Citations
    • 17 Article

    Mouse strain-specific acute respiratory effects of nicotine unrelated to nicotine metabolism

    Bloom, A. J., Sep 2 2019, In : Toxicology Mechanisms and Methods. 29, 7, p. 542-548 7 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes

    Bloom, A. J., Wang, P. F. & Kharasch, E. D., Apr 2019, In : Pharmacology Research and Perspectives. 7, 2, e00468.

    Research output: Contribution to journalArticle

    Open Access
  • 4 Scopus citations

    Strain-specific altered nicotine metabolism in 3,3′-diindolylmethane (DIM) exposed mice

    Bloom, A. J., Upadhyaya, P. & Kharasch, E. D., May 1 2019, In : Biopharmaceutics and Drug Disposition. 40, 5-6, p. 188-194 7 p.

    Research output: Contribution to journalArticle

  • CYP2A6 metabolism in the development of smoking behaviors in young adults

    Olfson, E., Bloom, J., Bertelsen, S., Budde, J. P., Breslau, N., Brooks, A., Culverhouse, R., Chan, G., Chen, L. S., Chorlian, D., Dick, D. M., Edenberg, H. J., Hartz, S., Hatsukami, D., Hesselbrock, V. M., Johnson, E. O., Kramer, J. R., Kuperman, S., Meyers, J. L., Nurnberger, J. & 8 others, Porjesz, B., Saccone, N. L., Schuckit, M. A., Stitzel, J., Tischfield, J. A., Rice, J. P., Goate, A. & Bierut, L. J., Jan 2018, In : Addiction Biology. 23, 1, p. 437-447 11 p.

    Research output: Contribution to journalArticle

  • 5 Scopus citations

    Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain

    Teitelbaum, A. M., Murphy, S. E., Akk, G., Baker, T. B., Germann, A., Von Weymarn, L. B., Bierut, L. J., Goate, A., Kharasch, E. D. & Bloom, A. J., Jan 1 2018, In : Pharmacogenomics Journal. 18, 1, p. 136-143 8 p.

    Research output: Contribution to journalArticle

  • 7 Scopus citations