Section of Stem Cell Biology

Research output

Research output per year 1981 2011 2012 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024

• 1068 Article
• 115 Review article
• 77 Comment/debate
• 58 Letter
• 48 More
  • 24 Chapter
  • 10 Short survey
  • 7 Editorial
  • 5 Conference contribution
  • 1 Book
  • 1 Conference article

Research output per year

Research output per year

Search results

• 2024

  A phase II study of interrupted and continuous dose lenalidomide in relapsed/refractory Hodgkin lymphoma

  Fehniger, T. A., Watkins, M. P., Ezenwajiaku, N., Wan, F., Hurd, D. D., Cashen, A. F., Blum, K. A., Goy, A., Fenske, T. S., Wagner-Johnston, N. D., Carson, K., Siegel, M. J., Russler-Germain, D., Schneider, S. E., Mehta-Shah, N., Kahl, B. & Bartlett, N. L., Mar 2024, In: Haematologica. 109, 3, p. 953-957 5 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

• Molecular responses in decitabine-and decitabine/venetoclax-Treated patients with acute myeloid leukemia and myelodysplastic syndromes

  Gruszczynska, A., Maiti, A., Miller, C. A., Ramakrishnan, S. M., Link, D. C., Uy, G. L., Petti, A. A., Hayes, K., Nardo, C. D. D., Ravandi, F., Ley, T. J., Spencer, D. H., Gao, F., Konopleva, M. Y. & Welch, J. S., 2024, In: Haematologica.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  1 Scopus citations
• 2023

  Clonal hematopoiesis in survivors of childhood cancer

  Friedman, D. N., Chan, I. C. C., Moskowitz, C. S., Li, S., Turner, K., Liu, J., Bouvier, N., Walsh, M. F., Spitzer, B., Kung, A. L., Berger, M., Cooper, M. A., Pusic, I., Uy, G., Link, D., Druley, T. E., Diaz, L. A., Levine, R. L., Shukla, N. & Bolton, K. L., Aug 8 2023, In: Blood Advances. 7, 15, p. 4102-4106 5 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  14 Scopus citations

• FDG-PET/CT response assessment with qualitative Lugano criteria outperforms change in SUV_max as a predictive biomarker in frontline treatment of mantle cell lymphoma

  Russler-Germain, D. A., Calhoun, B. R., Wu, N., Watkins, M. P., Siegel, B. A., Bartlett, N. L. & Mhlanga, J. C., 2023, In: Leukemia and Lymphoma. 64, 11, p. 1870-1874 5 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Scopus citations

• Overexpression of S100A9 in donor T cells is associated with reconstitution of gut microbiota and outcome of allogeneic hematopoietic stem cell transplantation

  Kim, S., Lim, S., Razmkhah, F. & Choi, J., Jun 2023, In: Blood Research. 58, 2, p. 105-111 7 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  1 Scopus citations

• Statin use in myelodysplastic syndromes is associated with a better survival and decreased progression to leukemia

  Afzal, A., Fiala, M. A., Jacoby, M. A. & Walter, M. J., Aug 8 2023, In: Blood Advances. 7, 15, p. 3838-3841 4 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  1 Scopus citations
• 2022

  Decitabine salvage for TP53-mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy

  Ferraro, F., Gruszczynska, A., Ruzinova, M. B., Miller, C. A., Percival, M. E., Uy, G. L., Pusic, I., Jacoby, M. A., Christopher, M. J., Kim, M. Y., Westervelt, P., Cashen, A. F., Schroeder, M. A., DiPersio, J. F., Abboud, C. N., Wartman, L. D., Gao, F., Link, D. C., Ley, T. J. & Welch, J. S., Jul 2022, In: Haematologica. 107, 7, p. 1709-1713 5 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  4 Scopus citations

• Discovery of a novel genomic alteration that renders leukemic cells resistant to CD19-targeted immunotherapies

  Ghobadi, A., Landmann, J. H., Carter, A., Cooper, M. L., Selli, M. E., Chang, J., Baker, M., Miller, C. A., Ferraro, F., Chen, D. Y., Smith, A. M., LaValle, T. A., Duncavage, E. J., Chou, J., Tam, V., Benoun, J. M., Nater, J., Scholler, N., Milletti, F. & Vezan, R. & 3 others, Bot, A., Rossi, J. M. & Singh, N., Oct 25 2022, In: Blood Advances. 6, 20, p. 5634-5640 7 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  2 Scopus citations

• DNMT3A overgrowth syndrome is associated with the development of hematopoietic malignancies in children and young adults

  Ferris, M. A., Smith, A. M., Heath, S. E., Duncavage, E. J., Oberley, M., Freyer, D., Wynn, R., Douzgou, S., Maris, J. M., Reilly, A. F., Wu, M. D., Choo, F., Fiets, R. B., Koene, S., Spencer, D. H., Miller, C. A., Shinawi, M. & Ley, T. J., Jan 20 2022, In: Blood. 139, 3, p. 461-464 4 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  13 Scopus citations

• Tumor suppressor function of WT1 in acute promyelocytic leukemia

  Christopher, M. J., Katerndahl, C. D. S., LeBlanc, H. R., Elmendorf, T. T., Basu, V., Gang, M., Menssen, A. J., Spencer, D. H., Duncavage, E. J., Ketkar, S., Wartman, L. D., Ramakrishnan, S. M., Miller, C. A. & Ley, T. J., Jan 2022, In: Haematologica. 107, 1, p. 342-346 5 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  6 Scopus citations
• 2021

  Genome sequencing in myeloid cancers

  Duncavage, E., Schroeder, M. & Spencer, D. H., Jun 24 2021, In: New England Journal of Medicine. 384, 25, e106.

  Research output: Contribution to journal › Letter › peer-review
  8 Scopus citations

• Outcomes of relapsed or refractory acute myeloid leukemia after front-line hypomethylating agent and venetoclax regimens

  Maiti, A., Rausch, C. R., Cortes, J. E., Pemmaraju, N., Daver, N. G., Ravandi, F., Garcia-Manero, G., Borthakur, G., Naqvi, K., Ohanian, M., Short, N. J., Alvarado, Y., Kadia, T. M., Takahashi, K., Yilmaz, M., Jain, N., Kornblau, S., Montalban-Bravo, G., Sasaki, K. & Andreeff, M. & 15 others, Bose, P., Ferrajoli, A., Issa, G. C., Jabbour, E. J., Masarova, L., Thompson, P. A., Wang, S., Konoplev, S., Pierce, S. A., Ning, J., Qiao, W., Welch, J. S., Kantarjian, H. M., DiNardo, C. D. & Konopleva, M. Y., Mar 2021, In: Haematologica. 106, 3, p. 894-898 5 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  91 Scopus citations
• 2020

  Haploinsufficiency of multiple del(5q) genes induce B cell abnormalities in mice

  Liu, T., Ahmed, T., Krysiak, K., Shirai, C. L., Shao, J., Nunley, R., Bucala, R., McKenzie, A., Ndonwi, M. & Walter, M. J., Sep 2020, In: Leukemia Research. 96, 106428.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  5 Scopus citations

• Predisposition to hematologic malignancies in patients with xeroderma pigmentosum

  Oetjen, K. A., Levoska, M. A., Tamura, D., Ito, S., Douglas, D., Khan, S. G., Calvo, K. R., Kraemer, K. H. & DiGiovanna, J. J., 2020, In: Haematologica. 105, 4, p. 1-11 11 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  20 Scopus citations

• Selective targeting of α4β1 integrin attenuates murine graft versus host disease

  Alahmari, B., Cooper, M. L., Vij, K., Ritchey, J., Ruminski, P., Gao, F., Choi, J. & DiPersio, J. F., Nov 1 2020, In: Leukemia. 34, 11, p. 3100-3104 5 p.

  Research output: Contribution to journal › Letter › peer-review
  7 Scopus citations

• Selinexor combined with cladribine, cytarabine, and filgrastim in relapsed or refractory acute myeloid leukemia

  Abboud, R., Chendamarai, E., Rettig, M. P., Trinkaus, K. M., Riedell, P. A., Abboud, C. N., Ghobadi, A., Pusic, I., Stockerl-Goldstein, K., Schroeder, M. A., Vij, R., Westervelt, P., DiPersio, J. F. & Uy, G. L., Aug 1 2020, In: Haematologica. 105, 8, p. E404-E407

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  15 Scopus citations
• 2019

  Exome analysis of treatment-related AML after APL suggests secondary evolution

  Wang, T., Jacoby, M. A., Duncavage, E. J., Miller, C. A., Heath, S., Rahme, R., Fenaux, P., Ades, L., Renneville, A., Cassinat, B., Takeshita, A., Asou, N., Miyazaki, Y., Kiyoi, H., Ravandi, F., Westervelt, P., Wartman, L. D. & Welch, J. S., Jun 2019, In: British Journal of Haematology. 185, 5, p. 984-987 4 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  1 Scopus citations

• Immune escape of AML cells after transplantation

  Christopher, M., DiPersio, J. F. & Ley, T. J., Mar 28 2019, In: New England Journal of Medicine. 380, 13, p. 1289-1290 2 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  1 Scopus citations

• Mortality-associated immunological abnormalities in trichothiodystrophy: correlation of reduced levels of immunoglobulin and neutrophils with poor patient survival

  Randall, G., Kraemer, K. H., Pugh, J., Tamura, D., DiGiovanna, J. J., Khan, S. G. & Oetjen, K. A., May 2019, In: British Journal of Haematology. 185, 4, p. 752-754 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  8 Scopus citations

• Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling

  Pollyea, D. A., Harris, C., Rabe, J. L., Hedin, B. R., De Arras, L., Katz, S., Wheeler, E., Bejar, R., Walter, M. J., Jordan, C. T., Pietras, E. M. & Alper, S., Aug 31 2019, In: Haematologica. 104, 9, p. E388-E392

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  44 Scopus citations

• TP53 immunohistochemistry correlates with TP53 mutation status and clearance in decitabine-treated patients with myeloid malignancies

  Ruzinova, M. B., Lee, Y. S., Duncavage, E. J. & Welch, J. S., Jul 31 2019, In: Haematologica. 104, 8, p. e345-e348

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  22 Scopus citations
• 2018

  Comment on: Evidence of innate lymphoid cell redundancy in humans

  Orange, J. S., Mace, E. M., French, A. R., Yokoyama, W. M., Fehniger, T. A. & Cooper, M. A., Aug 1 2018, In: Nature immunology. 19, 8, p. 788-789 2 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  9 Scopus citations

• DNMT3A ^R882 -associated hypomethylation patterns are maintained in primary AML xenografts, but not in the DNMT3A ^R882C OCI-AML3 leukemia cell line

  Chen, D., Christopher, M., Helton, N. M., Ferguson, I., Ley, T. J. & Spencer, D. H., Apr 1 2018, In: Blood cancer journal. 8, 4, 38.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  8 Scopus citations

• Germ line tissues for optimal detection of somatic variants in myelodysplastic syndromes

  Padron, E., Ball, M. C., Teer, J. K., Painter, J. S., Yoder, S. J., Zhang, C., Zhang, L., Moscinski, L. C., Rollison, D. E., Gore, S. D., Bejar, R., Walter, M. J., Sekeres, M. A., Komrokji, R. S. & Epling-Burnette, P. K., May 24 2018, In: Blood. 131, 21, p. 2402-2405 4 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  34 Scopus citations

• Ixazomib, an oral proteasome inhibitor, induces rapid mobilization of hematopoietic progenitor cells in mice

  Ghobadi, A., Rettig, M. P., Holt, M. S., Ritchey, J. K., Kennerly, K., Chendamarai, E., Eissenberg, L. & DiPersio, J. F., Jun 7 2018, In: Blood. 131, 23, p. 2594-2596 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  4 Scopus citations

• Loss of Toll-like receptor 2 results in accelerated leukemogenesis in the NUP98-HOXD13 mouse model of MDS

  Monlish, D. A., Bhatt, S. T., Duncavage, E. J., Greenberg, Z. J., Keller, J. L., Romine, M. P., Yang, W., Aplan, P. D., Walter, M. J. & Schuettpelz, L. G., Mar 1 2018, In: Blood. 131, 9, p. 1032-1035 4 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  12 Scopus citations

• Mutation Clearance after Transplantation for Myelodysplastic Syndrome

  Jacoby, M. A., Trinkaus, K. & Walter, M. J., Dec 13 2018, In: The New England journal of medicine. 379, 24, p. 2380 1 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
• 2017

  A phase 1/2 study of chemosensitization with plerixafor plus G-CSF in relapsed or refractory acute myeloid leukemia

  Uy, G. L., Rettig, M. P., Stone, R. M., Konopleva, M. Y., Andreeff, M., McFarland, K., Shannon, W., Fletcher, T. R., Reineck, T., Eades, W., Stockerl-Goldstein, K., Abboud, C. N., Jacoby, M. A., Westervelt, P. & Di Persio, J. F., Mar 10 2017, In: Blood cancer journal. 7, 3, e542.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  39 Scopus citations

• Long-term effects of G-CSF therapy in cyclic neutropenia

  Dale, D. C., Bolyard, A. A., Marrero, T., Vahagn, M., Bonilla, M. A., Link, D. C., Newburger, P., Shimamura, A., Boxer, L. A. & Spiekerman, C., Dec 7 2017, In: New England Journal of Medicine. 377, 23

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  32 Scopus citations

• Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy

  Duncavage, E. J., Uy, G. L., Petti, A. A., Miller, C. A., Lee, Y. S., Tandon, B., Gao, F., Fronick, C. C., O'Laughlin, M., Fulton, R. S., Wilson, R. K., Jacoby, M. A., Cashen, A. F., Wartman, L. D., Walter, M. J., Westervelt, P., Link, D. C., DiPersio, J. F., Ley, T. J. & Welch, J. S., Mar 9 2017, In: Blood. 129, 10, p. 1397-1401 5 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  24 Scopus citations

• Single institution experience with G-CSF mobilized T-cell replete haploidentical hematopoietic cell transplantation

  Huselton, E., Slade, M., Dipersio, J. F., Westervelt, P., Vij, R., Uy, G. L., Fehniger, T. A., Abboud, C. N., Gao, F., Schroeder, M. A. & Romee, R., May 1 2017, In: Bone Marrow Transplantation. 52, 5, p. 769-771 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  3 Scopus citations

• The authors reply

  Welch, J. S., Petti, A. A. & Ley, T. J., Feb 23 2017, In: New England Journal of Medicine. 376, 8, p. 797-798 2 p.

  Research output: Contribution to journal › Letter › peer-review
  28 Scopus citations
• 2016

  A genomic analysis of Philadelphia chromosome-negative AML arising in patients with CML

  Krysiak, K., Christopher, M. J., Skidmore, Z. L., Demeter, R. T., Magrini, V., Kunisaki, J., O'Laughlin, M., Duncavage, E. J., Miller, C. A., Ozenberger, B. A., Griffith, M., Wartman, L. D. & Griffith, O. L., Apr 8 2016, In: Blood cancer journal. 6, e413.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  13 Scopus citations

• Cytomegalovirus viremia, disease, and impact on relapse in T-cell replete peripheral blood haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide

  Goldsmith, S. R., Slade, M., Dipersio, J. F., Westervelt, P., Lawrence, S. J., Uy, G. L., Abboud, C. N., Vij, R., Schroeder, M. A., Fehniger, T. A., Dubberke, E. R., Trinkaus, K. & Romee, R., Oct 31 2016, In: Haematologica. 101, 11, p. e465-e468

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  50 Scopus citations

• DoCM: A database of curated mutations in cancer

  Ainscough, B. J., Griffith, M., Coffman, A. C., Wagner, A. H., Kunisaki, J., Choudhary, M. N. K., McMichael, J. F., Fulton, R. S., Wilson, R. K., Griffith, O. L. & Mardis, E. R., Oct 1 2016, In: Nature Methods. 13, 10, p. 806-807 2 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  85 Scopus citations

• Hand-foot syndrome following decitabine

  Ali, A. M., Jacoby, M. & Welch, J. S., Feb 1 2016, In: Annals of Hematology. 95, 3, p. 535-536 2 p.

  Research output: Contribution to journal › Letter › peer-review
  2 Scopus citations

• HLA disparity is not inconsequential in peripheral blood T-replete haploidentical hematopoietic stem cell transplantation

  Rashidi, A., Dipersio, J. F., Westervelt, P., Abboud, C. N., Schroeder, M. A., Pusic, I., Cashen, A. F., Fehniger, T. A. & Romee, R., Sep 1 2016, In: Bone Marrow Transplantation. 51, 9, p. 1275-1278 4 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  3 Scopus citations

• Phase-1/-2 study of pomalidomide in chronic GvHD

  Pusic, I., Rettig, M. P., Dipersio, J. F., Bauer, S., McFarland, K., Gale, R. P. & Pavletic, S. Z., Apr 1 2016, In: Bone Marrow Transplantation. 51, 4, p. 612-614 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  9 Scopus citations

• Targeted sequencing informs the evaluation of normal karyotype cytopenic patients for low-grade myelodysplastic syndrome

  Duncavage, E. J., O'Brien, J., Vij, K., Miller, C. A., Chang, G. S., Shao, J., Jacoby, M. A., Heath, S., Janke, M. R., Elliott, K., Fulton, R. S., Fronick, C., O'Laughlin, M., Westervelt, P., Ley, T. J., Wilson, R. K. & Walter, M. J., Dec 1 2016, In: Leukemia. 30, 12, p. 2422-2426 5 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  5 Scopus citations

• Vemurafenib for BRAF^V600E-positive metastatic papillary thyroid cancer – Authors' response

  Brose, M. S. & Singh, N., Nov 1 2016, In: The Lancet Oncology. 17, 11, p. e469

  Research output: Contribution to journal › Letter › peer-review

  Open Access
• 2015

  Absence of natural intracellular retinoids in mouse bone marrow cells and implications for PML-RARA transformation

  Niu, H., Chacko, J., Hadwiger, G. & Welch, J. S., Jan 1 2015, In: Blood cancer journal. 5, 2, e284.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  10 Scopus citations

• Acute Ether Lipid Deficiency Affects Neutrophil Biology in Mice

  Lodhi, I. J., Link, D. C. & Semenkovich, C. F., May 1 2015, In: Cell metabolism. 21, 5, p. 652-653 2 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  5 Scopus citations

• Quantifying ultra-rare pre-leukemic clones via targeted error-corrected sequencing

  Young, A. L., Wong, T. N., Hughes, A. E. O., Heath, S. E., Ley, T. J., Link, D. C. & Druley, T. E., Jul 13 2015, In: Leukemia. 29, 7, p. 1608-1611 4 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  72 Scopus citations
• 2014

  Bortezomib is a rapid mobilizer of hematopoietic stem cells in mice via modulation of the VCAM-1/VLA-4 axis

  Ghobadi, A., Rettig, M. P., Cooper, M. L., Holt, M. S., Ritchey, J. K., Eissenberg, L. & DiPersio, J. F., Oct 23 2014, In: Blood. 124, 17, p. 2752-2754 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  22 Scopus citations

• Haploidentical transplantation using G-CSF-mobilized T-cell replete PBSCs and post-transplantation CY after non-myeloablative conditioning is safe and is associated with favorable outcomes

  Bhamidipati, P. K., Dipersio, J. F., Stokerl-Goldstein, K., Rashidi, A., Gao, F., Uy, G. L., Westervelt, P., Vij, R., Schroeder, M. A., Abboud, C. N., Keller, J. W., Fehniger, T. A. & Romee, R., Aug 2014, In: Bone Marrow Transplantation. 49, 8, p. 1124-1126 3 p.

  Research output: Contribution to journal › Letter › peer-review
  23 Scopus citations

• Primary acute myeloid leukemia cells with IDH1 or IDH2 mutations respond to a DOT1L inhibitor in vitro

  Sarkaria, S. M., Christopher, M. J., Klco, J. M. & Ley, T. J., Dec 11 2014, In: Leukemia. 28, 12, p. 2403-2406 4 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  34 Scopus citations
• 2013

  The authors reply

  Miller, C. A., Wilson, R. K. & Ley, T. J., 2013, In: New England Journal of Medicine. 369, 15, p. 1473 1 p.

  Research output: Contribution to journal › Letter › peer-review
  48 Scopus citations
• 2011

  Combination decitabine, arsenic trioxide, and ascorbic acid for the treatment of myelodysplastic syndrome and acute myeloid leukemia: A phase I study

  Welch, J. S., Klco, J. M., Gao, F., Procknow, E., Uy, G. L., Stockerl-Goldstein, K. E., Abboud, C. N., Westervelt, P., DiPersio, J. F., Hassan, A., Cashen, A. F. & Vij, R., Sep 2011, In: American journal of hematology. 86, 9, p. 796-800 5 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  46 Scopus citations

• Red cell transfusion decreases hemoglobin A_1c in patients with diabetes

  Spencer, D. H., Grossman, B. J. & Scott, M. G., Feb 2011, In: Clinical chemistry. 57, 2, p. 344-346 3 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  50 Scopus citations

• Whole-genome sequencing and acute promyelocytic leukemia - Reply

  Westervelt, P., Welch, J. S. & Ley, T. J., Aug 10 2011, In: JAMA. 306, 6, p. 610-611 2 p.

  Research output: Contribution to journal › Letter › peer-review