Section of Multiple Sclerosis & Neuroimmunology

2025

A digital version of the nine-hole peg test: Speed may be a more reliable measure of upper-limb disability than completion time in patients with multiple sclerosis

Jiang, X., McGinley, M., Johnston, J., Alberts, J., Bermel, R., Ontaneda, D., Naismith, R. T., Hyde, R., Levitt, N., van Beek, J., Sun, Z., Campbell, N. & Barro, C., Jan 2025, In: Multiple Sclerosis Journal. 31, 1, p. 81-92 12 p.

Research output: Contribution to journal › Article › peer-review

A single-cell compendium of human cerebrospinal fluid identifies disease-associated immune cell populations

Cantoni, C., Smirnov, R. A., Firulyova, M., Andhey, P. S., Bradstreet, T. R., Esaulova, E., Terekhova, M., Schwarzkopf, E. A., Abdalla, N. M., Kleverov, M., Sabatino, J. J., Liu, K., Schwab, N., Meyer Zu Hörste, G., Cross, A. H., Artyomov, M. N., Edelson, B. T. & Wu, G. F., Jan 2 2025, In: Journal of Clinical Investigation. 135, 1, e177793.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Bile acid metabolites predict multiple sclerosis progression and supplementation is safe in progressive disease

Ladakis, D. C., Harrison, K. L., Smith, M. D., Solem, K., Gadani, S., Jank, L., Hwang, S., Farhadi, F., Dewey, B. E., Fitzgerald, K. C., Sotirchos, E. S., Saidha, S., Calabresi, P. A. & Bhargava, P., Mar 14 2025, In: Med. 6, 3, 100522.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Cerebrospinal fluid biomarkers as predictors of multiple sclerosis severity

Tolentino, M., Pace, F., Perantie, D. C., Mikesell, R., Huecker, J., Chahin, S., Ghezzi, L., Piccio, L. & Cross, A. H., Feb 2025, In: Multiple Sclerosis and Related Disorders. 94, 106268.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Claustrum Volume Is Reduced in Multiple Sclerosis and Predicts Disability

Shelley, N., Judge, B., Yablonskiy, D. A., Naismith, R. T., Brier, M. R. & Cross, A. H., Jun 2025, In: Annals of Clinical and Translational Neurology. 12, 6, p. 1100-1108 9 p.

Research output: Contribution to journal › Article › peer-review

Design and Synthesis of Novel PET Radiotracers for Imaging Sphingosine-1-Phosphate Receptor 5 (S1PR5) in the Brain

Lang, J., Zhou, W., Huang, T., Jiang, H., Chen, H., Xu, S., Qiu, L., Heady, M., Yu, Y., Brier, M. R., Nai, Y. H., Guglielmetti, C., Perlmutter, J. S. & Tu, Z., 2025, (Accepted/In press) In: Journal of Medicinal Chemistry.

Research output: Contribution to journal › Article › peer-review

Increased White Matter Aerobic Glycolysis in Multiple Sclerosis

Brier, M. R., Judge, B., Ying, C., Salter, A., An, H., Patel, A., Wang, Q., Wang, Y., Cross, A. H., Naismith, R. T., Benzinger, T. L. S. & Goyal, M. S., Apr 2025, In: Annals of neurology. 97, 4, p. 766-778 13 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Real world experience with cladribine tablets for multiple sclerosis at four academic multiple sclerosis centers

Conway, D. S., Nicholas, J. A., Thompson, N. R., Mowry, E. M. & Naismith, R. T., Feb 2025, In: Multiple Sclerosis and Related Disorders. 94, 106272.

Research output: Contribution to journal › Article › peer-review

Selection of therapeutically effective T-cell receptors from the diverse tumor-bearing repertoire

Rosenberger, L., Hansmann, L., Anastasopoulou, V., Wolf, S. P., Drousch, K., Moewes, C., Feng, X., Cao, G., Huang, J., Yew, P. Y., Strønen, E., Kato, T., Saligrama, N., Olweus, J., Nakamura, Y., Willimsky, G., Blankenstein, T., Schreiber, H. & Leisegang, M., May 2 2025, In: Journal for ImmunoTherapy of Cancer. 13, 5, e011351.

Research output: Contribution to journal › Article › peer-review

Open Access

Unraveling the major role of vascular (R2') contributions to R2* signal relaxation at ultra-high-field MRI: A comprehensive analysis with quantitative gradient recalled echo in mouse brain

Im, J., Xiang, B., Levasseur, V. A., Sukstanskii, A. L., Quirk, J. D., Kothapalli, S. V. V. N., Cross, A. H. & Yablonskiy, D. A., Aug 2025, In: Magnetic resonance in medicine. 94, 2, p. 761-770 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

A 2-stage model of heterogenous treatment effects for brain atrophy in multiple sclerosis utilizing the MS PATHS research network

Hersh, C. M., Sun, Z., Conway, D. S., Sotirchos, E. S., Fitzgerald, K. C., Hua, L. H., Ziemssen, T., Naismith, R. T., Pellegrini, F., Grossman, C. & Campbell, N., Nov 2024, In: Multiple Sclerosis and Related Disorders. 91, 105847.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice

Toth, K. A., Schmitt, E. G., Kolicheski, A., Greenberg, Z. J., Levendosky, E., Saucier, N., Trammel, K., Oikonomou, V., Lionakis, M. S., Klechevsky, E., Kim, B. S., Schuettpelz, L. G., Saligrama, N. & Cooper, M. A., Aug 5 2024, In: Journal of Experimental Medicine. 221, 8, e20232091.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination

Barclay, K. M., Abduljawad, N., Cheng, Z., Kim, M. W., Zhou, L., Yang, J., Rustenhoven, J., Mazzitelli, J. A., Smyth, L. C. D., Kapadia, D., Brioschi, S., Beatty, W., Hou, J. C., Saligrama, N., Colonna, M., Yu, G., Kipnis, J. & Li, Q., Jun 11 2024, In: Immunity. 57, 6, p. 1394-1412.e8

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Cis-regulatory evolution of the recently expanded Ly49 gene family

Fan, C., Xing, X., Murphy, S. J. H., Poursine-Laurent, J., Schmidt, H., Parikh, B. A., Yoon, J., Choudhary, M. N. K., Saligrama, N., Piersma, S. J., Yokoyama, W. M. & Wang, T., Dec 2024, In: Nature communications. 15, 1, 4839.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Concurrent administration of serotonergic antidepressants and ozanimod in participants with relapsing multiple sclerosis from the open-label extension DAYBREAK trial

Naismith, R. T., Cohen, J. A., Bar-Or, A., Comi, G., Selmaj, K. W. & Hartung, H. P., Feb 2024, In: Multiple Sclerosis Journal. 30, 2, p. 177-183 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Development of an LC-MS/MS Method to Measure Sphingolipids in CSF from Patients with Multiple Sclerosis^S

Perez-Paramo, Y. X., Dufield, D., Veeramachaneni, R., Parkhurst, E., Harp, C., Ramesh, A., Winger, R. C., Cross, A. H., Gelfand, J. M., Bar-Or, A., Rodney Mathews, W. & Anania, V. G., Mar 1 2024, In: Molecular pharmacology. 105, 3, p. 121-130 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Diagnostic Utility of Cerebrospinal Fluid Biomarkers in Patients with Rapidly Progressive Dementia

Kuchenbecker, L. A., Tipton, P. W., Martens, Y., Brier, M. R., Satyadev, N., Dunham, S. R., Lazar, E. B., Dacquel, M. V., Henson, R. L., Bu, G., Geschwind, M. D., Morris, J. C., Schindler, S. E., Herries, E., Graff-Radford, N. R. & Day, G. S., Feb 2024, In: Annals of neurology. 95, 2, p. 299-313 15 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Diffusion basis spectrum imaging and diffusion tensor imaging predict persistent black hole formation in multiple sclerosis

Wooliscroft, L., Salter, A., Adusumilli, G., Levasseur, V. A., Sun, P., Lancia, S., Perantie, D. C., Trinkaus, K., Naismith, R. T., Song, S. K. & Cross, A. H., Apr 2024, In: Multiple Sclerosis and Related Disorders. 84, 105494.

Research output: Contribution to journal › Article › peer-review

Open Access

Dimethyl fumarate preserves brainstem and cervical spinal cord integrity in radiologically isolated syndrome

on behalf of the ARISE Study Investigators, Okuda, D. T., Azevedo, C. J., Pelletier, D., Moog, T. M., Moazami, S., Rezvani, S., Bovis, F., Sormani, M. P., Siva, A., Kantarci, O., Lebrun-Frénay, C., Vargas, W. S., Stüve, O., Repovic, P., Pardo, G., Okuda, D. T., Okai, A., Naismith, R. T. & Mowry, E. M. & 4 others, Hua, L. H., Donlon, S., Azevedo, C. J. & Amezcua, L., Sep 2024, In: Journal of Neurology. 271, 9, p. 5899-5910 12 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Direct and Indirect Care of Patients With Multiple Sclerosis: Burden on Providers and Impact of Portal Messages

Mahmoud, R., Callahan, K., Schell, D., Carron, S. & Chahin, S., 2024, In: International Journal of MS Care. 26, 1, p. 13-16 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Emerging Cerebrospinal Fluid Biomarkers of Disease Activity and Progression in Multiple Sclerosis

Cross, A. H., Gelfand, J. M., Thebault, S., Bennett, J. L., Von Büdingen, H. C., Cameron, B., Carruthers, R., Edwards, K., Fallis, R., Gerstein, R., Giacomini, P. S., Greenberg, B., Hafler, D. A., Ionete, C., Kaunzner, U. W., Kodama, L., Lock, C., Longbrake, E. E., Musch, B. & Pardo, G. & 13 others, Piehl, F., Weber, M. S., Yuen, S., Ziemssen, T., Bose, G., Freedman, M. S., Anania, V. G., Ramesh, A., Winger, R. C., Jia, X., Herman, A., Harp, C. & Bar-Or, A., Apr 8 2024, In: JAMA Neurology. 81, 4, p. 373-383 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

Expanding clinical profiles and prognostic markers in stiff person syndrome spectrum disorders

Wang, Y., Hu, C., Aljarallah, S., Reyes Mantilla, M., Mukharesh, L., Simpson, A., Roy, S., Harrison, K., Shoemaker, T., Comisac, M., Balshi, A., Obando, D., Maldonado, D. A. P., Koshorek, J., Snoops, S., Fitzgerald, K. C. & Newsome, S. D., Apr 2024, In: Journal of Neurology. 271, 4, p. 1861-1872 12 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Exploring the association between weight loss-inducing medications and multiple sclerosis: insights from the FDA adverse event reporting system database

Shirani, A., Cross, A. H. & Stuve, O., Jan 1 2024, In: Therapeutic Advances in Neurological Disorders. 17

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Functional outcomes of diets in multiple sclerosis (FOOD for MS): Protocol for a parallel arm randomized feeding trial for low glycemic load and calorie restriction

Martin, K., Cofield, S. S., Cross, A. H., Goss, A. M., Raji, C. A., Rinker, J. R., Wu, G. F., Blair, J., Fuchs, A., Ghezzi, L., Green, K., Pace, F., Pastori, G., Taylor, M. G., Piccio, L. & Wingo, B. C., Aug 2024, In: Contemporary Clinical Trials. 143, 107584.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Improving Early Recognition of Treatment-Responsive Causes of Rapidly Progressive Dementia: The STAM₃P Score

Satyadev, N., Tipton, P. W., Martens, Y., Dunham, S. R., Geschwind, M. D., Morris, J. C., Brier, M. R., Graff-Radford, N. R. & Day, G. S., Feb 2024, In: Annals of neurology. 95, 2, p. 237-248 12 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Increased periventricular thalamic damage gradient in multiple sclerosis detected by quantitative gradient echo MRI

Samara, A., Xiang, B., Judge, B., Ciotti, J. R., Yablonskiy, D. A., Cross, A. H. & Brier, M. R., Oct 2024, In: Multiple Sclerosis and Related Disorders. 90, 105834.

Research output: Contribution to journal › Article › peer-review

Open Access

Metabolite Study and Structural Authentication for the First-in-Human Use Sphingosine-1-phosphate Receptor 1 Radiotracer

Qiu, L., Jiang, H., Cho, K., Yu, Y., Jones, L. A., Huang, T., Perlmutter, J. S., Gropler, R. J., Brier, M. R., Patti, G. J., Benzinger, T. L. S. & Tu, Z., May 1 2024, In: ACS Chemical Neuroscience. 15, 9, p. 1882-1892 11 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Prevalence of anti-myelin oligodendrocyte glycoprotein antibodies across neuroinflammatory and neurodegenerative diseases

Trivedi, R. R., Archambault, A. S., Pavlak, C., Gastaldi, M., Cantoni, C., Ghezzi, L., Cross, A. H., Miller, T. M. & Wu, G. F., Jun 15 2024, In: Journal of the Neurological Sciences. 461, 123041.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Randomised controlled trial of intermittent calorie restriction in people with multiple sclerosis

Ghezzi, L., Tosti, V., Shi, L., Cantoni, C., Mikesell, R., Lancia, S., Zhou, Y., Obert, K., Dula, C., Sen, M. K., Ge, A., Tolentino, M., Bollman, B., Don, A. S., Matarese, G., Colamatteo, A., La Rocca, C., Lepore, M. T., Raji, C. A. & Rahmani, F. & 6 others, Wu, G. F., Naismith, R. T., Fontana, L., Cross, A. H., Salter, A. & Piccio, L., Aug 20 2024, In: Journal of Neurology, Neurosurgery and Psychiatry. 96, 2

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Safety and efficacy of evobrutinib in relapsing multiple sclerosis (evolutionRMS1 and evolutionRMS2): two multicentre, randomised, double-blind, active-controlled, phase 3 trials

Montalban, X., Vermersch, P., Arnold, D. L., Bar-Or, A., Cree, B. A. C., Cross, A. H., Kubala Havrdova, E., Kappos, L., Stuve, O., Wiendl, H., Wolinsky, J. S., Dahlke, F., Le Bolay, C., Shen Loo, L., Gopalakrishnan, S., Hyvert, Y., Javor, A., Guehring, H., Tenenbaum, N. & Tomic, D., Nov 2024, In: The Lancet Neurology. 23, 11, p. 1119-1132 14 p.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Sex differences in plasma proteomic markers in late-life depression

Xue, X., Demirci, D., Lenze, E. J., Reynolds III, C. F., Mulsant, B. H., Wetherell, J. L., Wu, G. F., Blumberger, D. M., Karp, J. F., Butters, M. A., Mendes-Silva, A. P., Vieira, E. L., Tseng, G. & Diniz, B. S., Apr 2024, In: Psychiatry Research. 334, 115773.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Structural MRI measures are associated with fatigue severity and persistence in a large, real-world cohort of people with multiple sclerosis

Simpson, A. C., Hu, C., Mowry, E. M., Naismith, R. T., Fitzgerald, K. C. & Nourbakhsh, B., May 2024, In: Multiple Sclerosis Journal. 30, 6, p. 738-746 9 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Subcutaneous ocrelizumab in multiple sclerosis: Results of the Phase 1b OCARINA I study

Newsome, S. D., Goldstick, L., Robertson, D. S., Bowen, J. D., Naismith, R. T., Townsend, B., Figueiredo, C., Kletzl, H., Giraudon, M., Bortolami, O., Zecevic, D., Giacobino, C., Clinch, S., Shen, Y. A., Deol-Bhullar, G. & Bermel, R. A., Dec 2024, In: Annals of Clinical and Translational Neurology. 11, 12, p. 3215-3226 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Synaptic Protein Loss in Extracellular Vesicles Reflects Brain and Retinal Atrophy in People With Multiple Sclerosis

Ladakis, D. C., Vreones, M., Blommer, J., Harrison, K. L., Smith, M. D., Vasileiou, E. S., Moussa, H., Ahmadi, G., Ezzedin, O., Duval, A. L., Dewey, B. E., Prince, J. L., Fitzgerald, K. C., Sotirchos, E. S., Saidha, S., Calabresi, P. A., Kapogiannis, D. & Bhargava, P., May 16 2024, In: Neurology: Neuroimmunology and NeuroInflammation. 11, 4, e200257.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Twelve Weeks of Intermittent Caloric Restriction Diet Mitigates Neuroinflammation in Midlife Individuals with Multiple Sclerosis: A Pilot Study with Implications for Prevention of Alzheimer's Disease

Rahmani, F., Ghezzi, L., Tosti, V., Liu, J., Song, S. K., Wu, A. T., Rajamanickam, J., Obert, K. A., Benzinger, T. L. S., Mittendorfer, B., Piccio, L. & Raji, C. A., 2024, In: Advances in Alzheimer's Disease. 11, p. 156-166 11 p.

Research output: Contribution to journal › Article › peer-review

Unexpected Low Rate of Amyloid-β Pathology in Multiple Sclerosis Patients

Brier, M. R., Schindler, S. E., Salter, A., Perantie, D., Shelley, N., Judge, B., Keefe, S., Kirmess, K. M., Verghese, P. B., Yarasheski, K. E., Venkatesh, V., Raji, C. A., Gordon, B. A., Bateman, R. J., Morris, J. C., Naismith, R. T., Holtzman, D. M., Benzinger, T. L. S. & Cross, A. H., Sep 2024, In: Annals of neurology. 96, 3, p. 453-459 7 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

2023

Agreement between Published Reference Resources for Neurofilament Light Chain Levels in People with Multiple Sclerosis

Sotirchos, E. S., Hu, C., Smith, M. D., Lord, H. N., Duval, A. L., Arrambide, G., Montalban, X., Akgun, K., Ziemssen, T., Naismith, R. T., Hersh, C. M., Hyland, M., Krupp, L. B., Nicholas, J. A., Bermel, R. A., Mowry, E. M., Calabresi, P. A. & Fitzgerald, K. C., Dec 5 2023, In: Neurology. 101, 23, p. E2448-E2453

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Antibody response to SARS-CoV-2 vaccines in patients with relapsing multiple sclerosis treated with evobrutinib: A Bruton’s tyrosine kinase inhibitor

Bar-Or, A., Cross, A. H., Cunningham, A. L., Hyvert, Y., Seitzinger, A., Gühring, H., Drouin, E. E., Alexandri, N., Tomic, D. & Montalban, X., Oct 2023, In: Multiple Sclerosis Journal. 29, 11-12, p. 1471-1481 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Associations of sNfL with clinico-radiological measures in a large MS population

Sotirchos, E. S., Fitzgerald, K. C., Singh, C. M., Smith, M. D., Reyes-Mantilla, M., Hersh, C. M., Hyland, M. H., Canissario, R., Simmons, S. B., Arrambide, G., Montalban, X., Comabella, M., Naismith, R. T., Qiao, M., Krupp, L. B., Nicholas, J. A., Akgün, K., Ziemssen, T., Rudick, R. & Fisher, E. & 3 others, Bermel, R. A., Mowry, E. M. & Calabresi, P. A., Jan 2023, In: Annals of Clinical and Translational Neurology. 10, 1, p. 84-97 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

A TRPV4-dependent neuroimmune axis in the spinal cord promotes neuropathic pain

Hu, X., Du, L., Liu, S., Lan, Z., Zang, K., Feng, J., Zhao, Y., Yang, X., Xie, Z., Wang, P. L., Ver Heul, A. M., Chen, L., Samineni, V., Wang, Y. Q., Lavine, K., Gereau, R. W., Wu, G. & Hu, H., Mar 1 2023, In: Journal of Clinical Investigation. 133, 5, e161507.

Research output: Contribution to journal › Article › peer-review

Open Access

57 Scopus citations

Blood neurofilament light levels predict non-relapsing progression following anti-CD20 therapy in relapsing and primary progressive multiple sclerosis: findings from the ocrelizumab randomised, double-blind phase 3 clinical trials

Bar-Or, A., Thanei, G. A., Harp, C., Bernasconi, C., Bonati, U., Cross, A. H., Fischer, S., Gaetano, L., Hauser, S. L., Hendricks, R., Kappos, L., Kuhle, J., Leppert, D., Model, F., Sauter, A., Koendgen, H., Jia, X. & Herman, A. E., Jul 2023, In: EBioMedicine. 93, 104662.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

CAR-T Cell-Mediated B-Cell Depletion in Central Nervous System Autoimmunity

Gupta, S., Simic, M., Sagan, S. A., Shepherd, C., Duecker, J., Sobel, R. A., Dandekar, R., Wu, G. F., Wu, W., Pak, J. E., Hauser, S. L., Lim, W., Wilson, M. R. & Zamvil, S. S., Mar 19 2023, In: Neurology: Neuroimmunology and NeuroInflammation. 10, 2, e200080.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

Central Vein Sign in Pediatric Multiple Sclerosis and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease

Harrison, K. L., Gaudioso, C., Levasseur, V. A., Dunham, S. R., Schanzer, N., Keuchel, C., Salter, A., Goyal, M. S. & Mar, S., Sep 2023, In: Pediatric Neurology. 146, p. 21-25 5 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Cross-talk between B cells, microglia and macrophages, and implications to central nervous system compartmentalized inflammation and progressive multiple sclerosis

Touil, H., Li, R., Zuroff, L., Moore, C. S., Healy, L., Cignarella, F., Piccio, L., Ludwin, S., Prat, A., Gommerman, J., Bennett, F. C., Jacobs, D., Benjamins, J. A., Lisak, R. P., Antel, J. P. & Bar-Or, A., Oct 2023, In: EBioMedicine. 96, 104789.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation

Filipello, F., You, S. F., Mirfakhar, F. S., Mahali, S., Bollman, B., Acquarone, M., Korvatska, O., Marsh, J. A., Sivaraman, A., Martinez, R., Cantoni, C., De Feo, L., Ghezzi, L., Minaya, M. A., Renganathan, A., Cashikar, A. G., Satoh, J. I., Beatty, W., Iyer, A. K. & Cella, M. & 3 others, Raskind, W. H., Piccio, L. & Karch, C. M., Jun 2023, In: Acta Neuropathologica. 145, 6, p. 749-772 24 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Demographics and baseline disease characteristics of Black and Hispanic patients with multiple sclerosis in the open-label, single-arm, multicenter, phase IV CHIMES trial

CHIMES investigators, Williams, M. J., Okai, A. F., Cross, A. H., Monson, N. L., Vartanian, T., Thrower, B. W., Reder, A. T., English, J. B., Wu, G. F., Bernitsas, E., Yap, S., Ndrio, J., Pei, J., Mowry, E. M., Magrini, F., Acosta, J. & Amezcua, L., Aug 2023, In: Multiple Sclerosis and Related Disorders. 76, 104794.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity

Shinoda, K., Li, R., Rezk, A., Mexhitaj, I., Patterson, K. R., Kakara, M., Zuroff, L., Bennett, J. L., von Büdingen, H. C., Carruthers, R., Edwards, K. R., Fallis, R., Giacomini, P. S., Greenberg, B. M., Hafler, D. A., Ionete, C., Kaunzner, U. W., Lock, C. B., Longbrake, E. E. & Pardo, G. & 13 others, Piehl, F., Weber, M. S., Ziemssen, T., Jacobs, D., Gelfand, J. M., Cross, A. H., Cameron, B., Musch, B., Winger, R. C., Jia, X., Harp, C. T., Herman, A. & Bar-Ora, A., Jan 17 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 3, e2207291120.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Dimethyl Fumarate Delays Multiple Sclerosis in Radiologically Isolated Syndrome

Okuda, D. T., Kantarci, O., Lebrun-Frénay, C., Sormani, M. P., Azevedo, C. J., Bovis, F., Hua, L. H., Amezcua, L., Mowry, E. M., Hotermans, C., Mendoza, J., Walsh, J. S., von Hehn, C., Vargas, W. S., Donlon, S., Naismith, R. T., Okai, A., Pardo, G., Repovic, P. & Stüve, O. & 2 others, Siva, A. & Pelletier, D., Mar 2023, In: Annals of neurology. 93, 3, p. 604-614 11 p.

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Diroximel fumarate in patients with relapsing–remitting multiple sclerosis: Final safety and efficacy results from the phase 3 EVOLVE-MS-1 study

Singer, B. A., Arnold, D. L., Drulovic, J., Freedman, M. S., Gold, R., Gudesblatt, M., Jasinska, E., LaGanke, C. C., Naismith, R. T., Negroski, D., Oh, J., Hernandez Perez, M. A., Selmaj, K., Then Bergh, F., Wundes, A., Ziemssen, T., Castro-Borrero, W., Chen, H., Levin, S. & Scaramozza, M. & 3 others, Shankar, S. L., Wang, T. & Wray, S., Dec 2023, In: Multiple Sclerosis Journal. 29, 14, p. 1795-1807 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Early microglial response, myelin deterioration and lethality in mice deficient for very long chain ceramide synthesis in oligodendrocytes

Teo, J. D., Marian, O. C., Spiteri, A. G., Nicholson, M., Song, H., Khor, J. X. Y., McEwen, H. P., Ge, A., Sen, M. K., Piccio, L., Fletcher, J. L., King, N. J. C., Murray, S. S., Brüning, J. C. & Don, A. S., Apr 2023, In: Glia. 71, 4, p. 1120-1141 22 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Section of Multiple Sclerosis & Neuroimmunology

Research output

Search results