School of Medicine Vice Chancellor's Office

Research Output

2020

Mechanisms of action of autophagy modulators dissected by quantitative systems pharmacology analysis

Shi, Q., Pei, F., Silverman, G. A., Pak, S. C., Perlmutter, D. H., Liu, B. & Bahar, I., Apr 1 2020, In : International journal of molecular sciences. 21, 8, 2855.

Research output: Contribution to journalArticle

Open Access
2019

An analog of glibenclamide selectively enhances autophagic degradation of misfolded α1-antitrypsin Z

Wang, Y., Cobanoglu, M. C., Li, J., Hidvegi, T., Hale, P., Ewing, M., Chu, A. S., Gong, Z., Muzumdar, R., Pak, S. C., Silverman, G. A., Bahar, I. & Perlmutter, D. H., Jan 2019, In : PloS one. 14, 1, e0209748.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

NFκB mitigates the pathological effects of misfolded α1-antitrypsin by activating autophagy and an integrated program of proteostasis mechanisms

Mukherjee, A., Hidvegi, T., Araya, P., Ewing, M., Stolz, D. B. & Perlmutter, D. H., Mar 1 2019, In : Cell Death and Differentiation. 26, 3, p. 455-469 15 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Business of dialysis and the role of the medical director

Scheel, P. J., Mar 1 2018, In : Seminars in Dialysis. 31, 2, p. 177-182 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Quantitative assessment of cell fate decision between autophagy and apoptosis

Liu, B., Oltvai, Z. N., Baylr, H., Silverman, G. A., Pak, S. C., Perlmutter, D. H. & Bahar, I., Dec 1 2017, In : Scientific reports. 7, 1, 17605.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations
2016

Current and emerging treatments for alpha-1 antitrypsin deficiency

Perlmutter, D. H., Jul 2016, In : Gastroenterology and Hepatology. 12, 7, p. 446-448 3 p.

Research output: Contribution to journalComment/debate

3 Scopus citations
2015

Deficient and null variants of SERPINA1 are proteotoxic in a Caenorhabditis elegans model of α1-antitrypsin deficiency

Cummings, E. E., O'Reilly, L. P., King, D. E., Silverman, R. M., Miedel, M. T., Luke, C. J., Perlmutter, D. H., Silverman, G. A. & Pak, S. C., Oct 29 2015, In : PloS one. 10, 10, e0141542.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Does surgeon experience affect outcomes in pathologic stage i lung cancer?

Scheel, P. J., Crabtree, T. D., Bell, J. M., Frederiksen, C., Broderick, S. R., Krupnick, A. S., Kreisel, D., Patterson, G. A., Meyers, B. F. & Puri, V., Apr 1 2015, In : Journal of Thoracic and Cardiovascular Surgery. 149, 4, p. 998-1004.e1

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Enhancing autophagy with drugs or lung-directed gene therapy reverses the pathological effects of respiratory epithelial cell proteinopathy

Hidvegi, T., Stolz, D. B., Alcorn, J. F., Yousem, S. A., Wang, J., Leme, A. S., Houghton, A. M. G., Hale, P., Ewing, M., Cai, H., Garchar, E. A., Pastore, N., Annunziata, P., Kaminski, N., Pilewski, J., Shapiro, S. D., Pak, S. C., Silverman, G. A., Brunetti-Pierri, N. & Perlmutter, D. H., Dec 11 2015, In : Journal of Biological Chemistry. 290, 50, p. 29742-29757 16 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations

IndUced Pluripotent Stem Cells Model Personalized Variations in Liver Disease Resulting From α1-Antitrypsin Deficiency

Tafaleng, E. N., Chakraborty, S., Han, B., Hale, P., Wu, W., Soto-Gutierrez, A., Feghali-Bostwick, C. A., Wilson, A. A., Kotton, D. N., Nagaya, M., Strom, S. C., Roy-Chowdhury, J., Stolz, D. B., Perlmutter, D. H. & Fox, I. J., Jul 1 2015, In : Hepatology. 62, 1, p. 147-157 11 p.

Research output: Contribution to journalArticle

46 Scopus citations
2014

A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency

O'Reilly, L. P., Long, O. S., Cobanoglu, M. C., Benson, J. A., Luke, C. J., Miedel, M. T., Hale, P., Perlmutter, D. H., Bahar, I., Silverman, G. A. & Pak, S. C., Oct 1 2014, In : Human molecular genetics. 23, 19, p. 5123-5132 10 p.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

An instrumental variable approach finds no associated harm or benefit with early dialysis initiation in the United States

Scialla, J. J., Liu, J., Crews, D. C., Guo, H., Bandeen-Roche, K., Ephraim, P. L., Tangri, N., Sozio, S. M., Shafi, T., Miskulin, D. C., Michels, W. M., Jaar, B. G., Wu, A. W., Powe, N. R., Boulware, E. L., Cook, C., Coresh, J., Kim, J., Liu, Y., Luly, J. & 18 others, McDermott, A., Scheel, P., Zhou, J., Collins, A., Foley, R., Gilbertson, D., Heubner, B., Herzog, C., St Peter, W., Nally, J., Arrigain, S., Jolly, S., Konig, V., Liu, X., Navaneethan, S., Schold, J., Zager, P. & Meyer, K., Jan 1 2014, In : Kidney International. 86, 4, p. 798-809 12 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Targeting intracellular degradation pathways for treatment of liver disease caused by α1-antitrypsin deficiency

Wang, Y. & Perlmutter, D. H., Jan 2014, In : Pediatric research. 75, 1-2, p. 133-139 7 p.

Research output: Contribution to journalReview article

Open Access
10 Scopus citations
2012

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L., Alegre-Abarrategui, J. & 1,249 others, Aleo, M. F., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H. J., Chai, C. Y., Chan, D. C., Chan, E. Y., Chang, R. C. C., Che, C. M., Chen, C. C., Chen, G. C., Chen, G. Q., Chen, M., Chen, Q., Chen, S. S. L., Chen, W. L., Chen, X., Chen, X., Chen, X., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Cheong, H., Cheong, J. H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H. L., Chiarelli, R., Chiba, T., Chin, L. S., Chiou, S. H., Chisari, F. V., Cho, C. H., Cho, D. H., Choi, A. M. K., Choi, D. S., Choi, K. S., Choi, M. E., Chouaib, S., Choubey, D., Choubey, V., Chu, C. T., Chuang, T. H., Chueh, S. H., Chun, T., Chwae, Y. J., Chye, M. L., Ciarcia, R., Ciriolo, M. R., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Clarke, R., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condello, M., Condorelli, F., Cookson, M. R., Coombs, G. H., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F. P., Cregg, J. M., Crespo, J. L., Cronjé, M. J., Cuervo, A. M., Cullen, J. J., Czaja, M. J., D'Amelio, M., Darfeuille-Michaud, A., Davids, L. M., Davies, F. E., De Felici, M., De Groot, J. F., De Haan, C. A. M., De Martino, L., De Milito, A., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L. M. D., Demarchi, F., Deng, Y. Z., Dengjel, J., Dent, P., Denton, D., Deretic, V., Desai, S. D., Devenish, R. J., Di Gioacchino, M., Di Paolo, G., Di Pietro, C., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dikic, I., Dinesh-Kumar, S. P., Ding, W. X., Distelhorst, C. W., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Dorsey, F. C., Dosenko, V., Dowling, J. J., Doxsey, S., Dreux, M., Drew, M. E., Duan, Q., Duchosal, M. A., Duff, K., Dugail, I., Durbeej, M., Duszenko, M., Edelstein, C. L., Edinger, A. L., Egea, G., Eichinger, L., Eissa, N. T., Ekmekcioglu, S., El-Deiry, W. S., Elazar, Z., Elgendy, M., Ellerby, L. M., Er Eng, K., Engelbrecht, A. M., Engelender, S., Erenpreisa, J., Escalante, R., Esclatine, A., Eskelinen, E. L., Espert, L., Espina, V., Fan, H., Fan, J., Fan, Q. W., Fan, Z., Fang, S., Fang, Y., Fanto, M., Fanzani, A., Farkas, T., Farré, J. C., Faure, M., Fechheimer, M., Feng, C. G., Feng, J., Feng, Q., Feng, Y., Fésüs, L., Feuer, R., Figueiredo-Pereira, M. E., Fimia, G. M., Fingar, D. C., Finkbeiner, S., Finkel, T., Finley, K. D., Fiorito, F., Fisher, E. A., Fisher, P. B., Flajolet, M., Florez-McClure, M. L., Florio, S., Fon, E. A., Fornai, F., Fortunato, F., Fotedar, R., Fowler, D. H., Fox, H. S., Franco, R., Frankel, L. B., Fransen, M., Fuentes, J. M., Fueyo, J., Fujii, J., Fujisaki, K., Fujita, E., Fukuda, M., Furukawa, R. H., Gaestel, M., Gailly, P., Gajewska, M., Galliot, B., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I. G., Gao, F. B., Gao, G. F., Gao, J., Garcia, L., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A. L., Gatti, E., Gautel, M., Gawriluk, T. R., Gegg, M. E., Geng, J., Germain, M., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghosh, P., Giammarioli, A. M., Giatromanolaki, A. N., Gibson, S. B., Gilkerson, R. W., Ginger, M. L., Ginsberg, H. N., Golab, J., Goligorsky, M. S., Golstein, P., Gomez-Manzano, C., Goncu, E., Gongora, C., Gonzalez, C. D., Gonzalez, R., González-Estévez, C., González-Polo, R. A., Gonzalez-Rey, E., Gorbunov, N. V., Gorski, S., Goruppi, S., Gottlieb, R. A., Gozuacik, D., Granato, G. E., Grant, G. D., Green, K. N., Gregorc, A., Gros, F., Grose, C., Grunt, T. W., Gual, P., Guan, J. L., Guan, K. L., Guichard, S. M., Gukovskaya, A. S., Gukovsky, I., Gunst, J., Gustafsson, A. B., Halayko, A. J., Hale, A. N., Halonen, S. K., Hamasaki, M., Han, F., Han, T., Hancock, M. K., Hansen, M., Harada, H., Harada, M., Hardt, S. E., Harper, J. W., Harris, A. L., Harris, J., Harris, S. D., Hashimoto, M., Haspel, J. A., Hayashi, S. I., Hazelhurst, L. A., He, C., He, Y. W., Hébert, M. J., Heidenreich, K. A., Helfrich, M. H., Helgason, G. V., Henske, E. P., Herman, B., Herman, P. K., Hetz, C., Hilfiker, S., Hill, J. A., Hocking, L. J., Hofman, P., Hofmann, T. G., Höhfeld, J., Holyoake, T. L., Hong, M. H., Hood, D. A., Hotamisligil, G. S., Houwerzijl, E. J., Høyer-Hansen, M., Hu, B., Hu, C. A. A., Hu, H. M., Hua, Y., Huang, C., Huang, J., Huang, S., Huang, W. P., Huber, T. B., Huh, W. K., Hung, T. H., Hupp, T. R., Hur, G. M., Hurley, J. B., Hussain, S. N. A., Hussey, P. J., Hwang, J. J., Hwang, S., Ichihara, A., Ilkhanizadeh, S., Inoki, K., Into, T., Iovane, V., Iovanna, J. L., Ip, N. Y., Isaka, Y., Ishida, H., Isidoro, C., Isobe, K. I., Iwasaki, A., Izquierdo, M., Izumi, Y., Jaakkola, P. M., Jäättelä, M., Jackson, G. R., Jackson, W. T., Janji, B., Jendrach, M., Jeon, J. H., Jeung, E. B., Jiang, H., Jiang, H., Jiang, J. X., Jiang, M., Jiang, Q., Jiang, X., Jiménez, A., Jin, M., Jin, S., Joe, C. O., Johansen, T., Johnson, D. E., Johnson, G. V. W., Jones, N. L., Joseph, B., Joseph, S. K., Joubert, A. M., Juhász, G., Juillerat-Jeanneret, L., Jung, C. H., Jung, Y. K., Kaarniranta, K., Kaasik, A., Kabuta, T., Kadowaki, M., Kagedal, K., Kamada, Y., Kaminskyy, V. O., Kampinga, H. H., Kanamori, H., Kang, C., Kang, K. B., Il Kang, K., Kang, R., Kang, Y. A., Kanki, T., Kanneganti, T. D., Kanno, H., Kanthasamy, A. G., Kanthasamy, A., Karantza, V., Kaushal, G. P., Kaushik, S., Kawazoe, Y., Ke, P. Y., Kehrl, J. H., Kelekar, A., Kerkhoff, C., Kessel, D. H., Khalil, H., Kiel, J. A. K. W., Kiger, A. A., Kihara, A., Kim, D. R., Kim, D. H., Kim, D. H., Kim, E. K., Kim, H. R., Kim, J. S., Kim, J. H., Kim, J. C., Kim, J. K., Kim, P. K., Kim, S. W., Kim, Y. S., Kim, Y., Kimchi, A., Kimmelman, A. C., King, J. S., Kinsella, T. J., Kirkin, V., Kirshenbaum, L. A., Kitamoto, K., Kitazato, K., Klein, L., Klimecki, W. T., Klucken, J., Knecht, E., Ko, B. C. B., Koch, J. C., Koga, H., Koh, J. Y., Koh, Y. H., Koike, M., Komatsu, M., Kominami, E., Kong, H. J., Kong, W. J., Korolchuk, V. I., Kotake, Y., Koukourakis, M. I., Kouri Flores, J. B., Kovács, A. L., Kraft, C., Krainc, D., Krämer, H., Kretz-Remy, C., Krichevsky, A. M., Kroemer, G., Krüger, R., Krut, O., Ktistakis, N. T., Kuan, C. Y., Kucharczyk, R., Kumar, A., Kumar, R., Kumar, S., Kundu, M., Kung, H. J., Kurz, T., Kwon, H. J., La Spada, A. R., Lafont, F., Lamark, T., Landry, J., Lane, J. D., Lapaquette, P., Laporte, J. F., László, L., Lavandero, S., Lavoie, J. N., Layfield, R., Lazo, P. A., Le, W., Le Cam, L., Ledbetter, D. J., Lee, A. J. X., Lee, B. W., Lee, G. M., Lee, J., Lee, J. H., Lee, M., Lee, M. S., Lee, S. H., Leeuwenburgh, C., Legembre, P., Legouis, R., Lehmann, M., Lei, H. Y., Lei, Q. Y., Leib, D. A., Leiro, J., Lemasters, J. J., Lemoine, A., Lesniak, M. S., Lev, D., Levenson, V. V., Levine, B., Levy, E., Li, F., Li, J. L., Li, L., Li, S., Li, W., Li, X. J., Li, Y. B., Li, Y. P., Liang, C., Liang, Q., Liao, Y. F., Liberski, P. P., Lieberman, A., Lim, H. J., Lim, K. L., Lim, K., Lin, C. F., Lin, F. C., Lin, J., Lin, J. D., Lin, K., Lin, W. W., Lin, W. C., Lin, Y. L., Linden, R., Lingor, P., Lippincott-Schwartz, J., Lisanti, M. P., Liton, P. B., Liu, B., Liu, C. F., Liu, K., Liu, L., Liu, Q. A., Liu, W., Liu, Y. C., Liu, Y., Lockshin, R. A., Lok, C. N., Lonial, S., Loos, B., Lopez-Berestein, G., López-Otín, C., Lossi, L., Lotze, M. T., Lõw, P., Lu, B., Lu, B., Lu, B., Lu, Z., Luciano, F., Lukacs, N. W., Lund, A. H., Lynch-Day, M. A., Ma, Y., Macian, F., MacKeigan, J. P., Macleod, K. F., Madeo, F., Maiuri, L., Maiuri, M. C., Malagoli, D., Malicdan, M. C. V., Malorni, W., Man, N., Mandelkow, E. M., Manon, S., Manov, I., Mao, K., Mao, X., Mao, Z., Marambaud, P., Marazziti, D., Marcel, Y. L., Marchbank, K., Marchetti, P., Marciniak, S. J., Marcondes, M., Mardi, M., Marfe, G., Mariño, G., Markaki, M., Marten, M. R., Martin, S. J., Martinand-Mari, C., Martinet, W., Martinez-Vicente, M., Masini, M., Matarrese, P., Matsuo, S., Matteoni, R., Mayer, A., Mazure, N. M., McConkey, D. J., McConnell, M. J., McDermott, C., McDonald, C., McInerney, G. M., McKenna, S. L., McLaughlin, B. A., McLean, P. J., McMaster, C. R., McQuibban, G. A., Meijer, A. J., Meisler, M. H., Meléndez, A., Melia, T. J., Melino, G., Mena, M. A., Menendez, J. A., Menna-Barreto, R. F. S., Menon, M. B., Menzies, F. M., Mercer, C. A., Merighi, A., Merry, D. E., Meschini, S., Meyer, C. G., Meyer, T. F., Miao, C. Y., Miao, J. Y., Michels, P. A. M., Michiels, C., Mijaljica, D., Milojkovic, A., Minucci, S., Miracco, C., Miranti, C. K., Mitroulis, I., Miyazawa, K., Mizushima, N., Mograbi, B., Mohseni, S., Molero, X., Mollereau, B., Mollinedo, F., Momoi, T., Monastyrska, I., Monick, M. M., Monteiro, M. J., Moore, M. N., Mora, R., Moreau, K., Moreira, P. I., Moriyasu, Y., Moscat, J., Mostowy, S., Mottram, J. C., Motyl, T., Moussa, C. E. H., Müller, S., Muller, S., Münger, K., Münz, C., Murphy, L. O., Murphy, M. E., Musarò, A., Mysorekar, I., Nagata, E., Nagata, K., Nahimana, A., Nair, U., Nakagawa, T., Nakahira, K., Nakano, H., Nakatogawa, H., Nanjundan, M., Naqvi, N. I., Narendra, D. P., Narita, M., Navarro, M., Nawrocki, S. T., Nazarko, T. Y., Nemchenko, A., Netea, M. G., Neufeld, T. P., Ney, P. A., Nezis, I. P., Nguyen, H. P., Nie, D., Nishino, I., Nislow, C., Nixon, R. A., Noda, T., Noegel, A. A., Nogalska, A., Noguchi, S., Notterpek, L., Novak, I., Nozaki, T., Nukina, N., Nürnberger, T., Nyfeler, B., Obara, K., Oberley, T. D., Oddo, S., Ogawa, M., Ohashi, T., Okamoto, K., Oleinick, N. L., Oliver, F. J., Olsen, L. J., Olsson, S., Opota, O., Osborne, T. F., Ostrander, G. K., Otsu, K., Ou, J. H. J., Ouimet, M., Overholtzer, M., Ozpolat, B., Paganetti, P., Pagnini, U., Pallet, N., Palmer, G. E., Palumbo, C., Pan, T., Panaretakis, T., Pandey, U. B., Papackova, Z., Papassideri, I., Paris, I., Park, J., Park, O. K., Parys, J. B., Parzych, K. R., Patschan, S., Patterson, C., Pattingre, S., Pawelek, J. M., Peng, J., Perlmutter, D. H., Perrotta, I., Perry, G., Pervaiz, S., Peter, M., Peters, G. J., Petersen, M., Petrovski, G., Phang, J. M., Piacentini, M., Pierre, P., Pierrefite-Carle, V., Pierron, G., Pinkas-Kramarski, R., Piras, A., Piri, N., Platanias, L. C., Pöggeler, S., Poirot, M., Poletti, A., Poüs, C., Pozuelo-Rubio, M., Prætorius-Ibba, M., Prasad, A., Prescott, M., Priault, M., Produit-Zengaffinen, N., Progulske-Fox, A., Proikas-Cezanne, T., Przedborski, S., Przyklenk, K., Puertollano, R., Puyal, J., Qian, S. B., Qin, L., Qin, Z. H., Quaggin, S. E., Raben, N., Rabinowich, H., Rabkin, S. W., Rahman, I., Rami, A., Ramm, G., Randall, G., Randow, F., Rao, V. A., Rathmell, J. C., Ravikumar, B., Ray, S. K., Reed, B. H., Reed, J. C., Reggiori, F., Régnier-Vigouroux, A., Reichert, A. S., Reiners, J. J., Reiter, R. J., Ren, J., Revuelta, J. L., Rhodes, C. J., Ritis, K., Rizzo, E., Robbins, J., Roberge, M., Roca, H., Roccheri, M. C., Rocchi, S., Rodemann, H. P., De Córdoba, S. R., Rohrer, B., Roninson, I. B., Rosen, K., Rost-Roszkowska, M. M., Rouis, M., Rouschop, K. M. A., Rovetta, F., Rubin, B. P., Rubinsztein, D. C., Ruckdeschel, K., Rucker, E. B., Rudich, A., Rudolf, E., Ruiz-Opazo, N., Russo, R., Rusten, T. E., Ryan, K. M., Ryter, S. W., Sabatini, D. M., Sadoshima, J., Saha, T., Saitoh, T., Sakagami, H., Sakai, Y., Salekdeh, G. H., Salomoni, P., Salvaterra, P. M., Salvesen, G., Salvioli, R., Sanchez, A. M. J., Sánchez-Alcázar, J. A., Sánchez-Prieto, R., Sandri, M., Sankar, U., Sansanwal, P., Santambrogio, L., Saran, S., Sarkar, S., Sarwal, M., Sasakawa, C., Sasnauskiene, A., Sass, M., Sato, K., Sato, M., Schapira, A. H. V., Scharl, M., Schätzl, H. M., Scheper, W., Schiaffino, S., Schneider, C., Schneider, M. E., Schneider-Stock, R., Schoenlein, P. V., Schorderet, D. F., Schüller, C., Schwartz, G. K., Scorrano, L., Sealy, L., Seglen, P. O., Segura-Aguilar, J., Seiliez, I., Seleverstov, O., Sell, C., Seo, J. B., Separovic, D., Setaluri, V., Setoguchi, T., Settembre, C., Shacka, J. J., Shanmugam, M., Shapiro, I. M., Shaulian, E., Shaw, R. J., Shelhamer, J. H., Shen, H. M., Shen, W. C., Sheng, Z. H., Shi, Y., Shibuya, K., Shidoji, Y., Shieh, J. J., Shih, C. M., Shimada, Y., Shimizu, S., Shintani, T., Shirihai, O. S., Shore, G. C., Sibirny, A. A., Sidhu, S. B., Sikorska, B., Silva-Zacarin, E. C. M., Simmons, A., Simon, A. K., Simon, H. U., Simone, C., Simonsen, A., Sinclair, D. A., Singh, R., Sinha, D., Sinicrope, F. A., Sirko, A., Siu, P. M., Sivridis, E., Skop, V., Skulachev, V. P., Slack, R. S., Smaili, S. S., Smith, D. R., Soengas, M. S., Soldati, T., Song, X., Sood, A. K., Soong, T. W., Sotgia, F., Spector, S. A., Spies, C. D., Springer, W., Srinivasula, S. M., Stefanis, L., Steffan, J. S., Stendel, R., Stenmark, H., Stephanou, A., Stern, S. T., Sternberg, C., Stork, B., Strålfors, P., Subauste, C. S., Sui, X., Sulzer, D., Sun, J., Sun, S. Y., Sun, Z. J., Sung, J. J. Y., Suzuki, K., Suzuki, T., Swanson, M. S., Swanton, C., Sweeney, S. T., Sy, L. K., Szabadkai, G., Tabas, I., Taegtmeyer, H., Tafani, M., Takács-Vellai, K., Takano, Y., Takegawa, K., Takemura, G., Takeshita, F., Talbot, N. J., Tan, K. S. W., Tanaka, K., Tanaka, K., Tang, D., Tang, D., Tanida, I., Tannous, B. A., Tavernarakis, N., Taylor, G. S., Taylor, G. A., Taylor, J. P., Terada, A. S., Terman, A., Tettamanti, G., Thevissen, K., Thompson, C. B., Thorburn, A., Thumm, M., Tian, F. F., Tian, Y., Tocchini-Valentini, G., Tolkovsky, A. M., Tomino, Y., Tönges, L., Tooze, S. A., Tournier, C., Tower, J., Towns, R., Trajkovic, V., Travassos, L. H., Tsai, T. F., Tschan, M. P., Tsubata, T., Tsung, A., Turk, B., Turner, L. S., Tyagi, S. C., Uchiyama, Y., Ueno, T., Umekawa, M., Umemiya-Shirafuji, R., Unni, V. K., Vaccaro, M. I., Valente, E. M., Van Den Berghe, G., Van Der Klei, I. J., Van Doorn, W. G., Van Dyk, L. F., Van Egmond, M., Van Grunsven, L. A., Vandenabeele, P., Vandenberghe, W. P., Vanhorebeek, I., Vaquero, E. C., Velasco, G., Vellai, T., Vicencio, J. M., Vierstra, R. D., Vila, M., Vindis, C., Viola, G., Viscomi, M. T., Voitsekhovskaja, O. V., Von Haefen, C., Votruba, M., Wada, K., Wade-Martins, R., Walker, C. L., Walsh, C. M., Walter, J., Wan, X. B., Wang, A., Wang, C., Wang, D., Wang, F., Wang, F., Wang, G., Wang, H., Wang, H. G., Wang, H. D., Wang, J., Wang, K., Wang, M., Wang, R. C., Wang, X., Wang, X., Wang, Y. J., Wang, Y., Wang, Z., Wang, Z. C., Wang, Z., Wansink, D. G., Ward, D. M., Watada, H., Waters, S. L., Webster, P., Wei, L., Weihl, C. C., Weiss, W. A., Welford, S. M., Wen, L. P., Whitehouse, C. A., Whitton, J. L., Whitworth, A. J., Wileman, T., Wiley, J. W., Wilkinson, S., Willbold, D., Williams, R. L., Williamson, P. R., Wouters, B. G., Wu, C., Wu, D. C., Wu, W. K. K., Wyttenbach, A., Xavier, R. J., Xi, Z., Xia, P., Xiao, G., Xie, Z., Xie, Z., Xu, D. Z., Xu, J., Xu, L., Xu, X., Yamamoto, A., Yamamoto, A., Yamashina, S., Yamashita, M., Yan, X., Yanagida, M., Yang, D. S., Yang, E., Yang, J. M., Yang, S. Y., Yang, W., Yang, W. Y., Yang, Z., Yao, M. C., Yao, T. P., Yeganeh, B., Yen, W. L., Yin, J. J., Yin, X. M., Yoo, O. J., Yoon, G., Yoon, S. Y., Yorimitsu, T., Yoshikawa, Y., Yoshimori, T., Yoshimoto, K., You, H. J., Youle, R. J., Younes, A., Yu, L., Yu, L., Yu, S. W., Yu, W. H., Yuan, Z. M., Yue, Z., Yun, C. H., Yuzaki, M., Zabirnyk, O., Silva-Zacarin, E., David Zacks, E., Zacksenhaus, L., Zaffaroni, N., Zakeri, Z., Zeh, H. J., Zeitlin, S. O., Zhang, H., Zhang, H. L., Zhang, J., Zhang, J. P., Zhang, L., Zhang, L., Zhang, M. Y., Zhang, X. D., Zhao, M., Zhao, Y. F., Zhao, Y., Zhao, Z. J., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, C. Z., Zhu, C., Zhu, W. G., Zhu, X. F., Zhu, X., Zhu, Y., Zoladek, T., Zong, W. X., Zorzano, A., Zschocke, J. & Zuckerbraun, B., Apr 1 2012, In : Autophagy. 8, 4, p. 445-544 100 p.

Research output: Contribution to journalReview article

Open Access
2492 Scopus citations
2011

Association between pregnancy complications and small-for-gestational-age birth weight defined by customized fetal growth standard versus a population-based standard

Odibo, A. O., Francis, A., Cahill, A. G., MacOnes, G. A., Crane, J. P. & Gardosi, J., Mar 1 2011, In : Journal of Maternal-Fetal and Neonatal Medicine. 24, 3, p. 411-417 7 p.

Research output: Contribution to journalArticle

46 Scopus citations
Open Access
24 Scopus citations
2010

Effect of placenta previa on fetal growth

Harper, L. M., Odibo, A. O., MacOnes, G. A., Crane, J. P. & Cahill, A. G., Oct 2010, In : American journal of obstetrics and gynecology. 203, 4, p. 330.e1-330.e5

Research output: Contribution to journalArticle

35 Scopus citations

Is chorionic villus sampling associated with hypertensive disorders of pregnancy?

Odibo, A. O., Singla, A., Gray, D. L., Dicke, J. M., Oberle, B. & Crane, J., Jan 1 2010, In : Prenatal Diagnosis. 30, 1, p. 9-13 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Leiomyomas at routine second-trimester ultrasound examination and adverse obstetric outcomes

Stout, M. J., Odibo, A. O., Graseck, A. S., MacOnes, G. A., Crane, J. P. & Cahill, A. G., Nov 2010, In : Obstetrics and gynecology. 116, 5, p. 1056-1063 8 p.

Research output: Contribution to journalArticle

85 Scopus citations

Single umbilical artery and its associated findings

Hua, M., Odibo, A. O., MacOnes, G. A., Roehl, K. A., Crane, J. P. & Cahill, A. G., Sep 1 2010, In : Obstetrical and Gynecological Survey. 65, 9, p. 558-559 2 p.

Research output: Contribution to journalComment/debate

Single umbilical artery and its associated findings

Hua, M., Odibo, A. O., MacOnes, G. A., Roehl, K. A., Crane, J. P. & Cahill, A. G., May 1 2010, In : Obstetrics and gynecology. 115, 5, p. 930-934 5 p.

Research output: Contribution to journalArticle

67 Scopus citations

Ultrasound-detected subchorionic hemorrhage and the obstetric implications

Norman, S. M., Odibo, A. O., Macones, G. A., Dicke, J. M., Crane, J. P. & Cahill, A. G., Aug 2010, In : Obstetrics and gynecology. 116, 2, p. 311-315 5 p.

Research output: Contribution to journalArticle

25 Scopus citations
2009

In reply

Odibo, A., Gray, D. L., Dicke, J. M. & Crane, J. P., Feb 1 2009, In : Obstetrics and gynecology. 113, 2 PART 1, 1 p.

Research output: Contribution to journalLetter

Pregnancy loss rate after mid-trimester amniocentesis in twin pregnancies

Cahill, A. G., Macones, G. A., Stamilio, D. M., Dicke, J. M., Crane, J. P. & Odibo, A. O., Mar 2009, In : American journal of obstetrics and gynecology. 200, 3, p. 257.e1-257.e6

Research output: Contribution to journalArticle

45 Scopus citations
2008

Evaluating the rate and risk factors for fetal loss after chorionic villus sampling

Odibo, A. O., Dicke, J. M., Gray, D. L., Oberle, B., Stamilio, D. M., MacOnes, G. A. & Crane, J. P., Oct 1 2008, In : Obstetrics and gynecology. 112, 4, p. 813-819 7 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Revisiting the fetal loss rate after second-trimester genetic amniocentesis: A single center's 16-year experience

Odibo, A. O., Gray, D. L., Dicke, J. M., Stamilio, D. M., Macones, G. A. & Crane, J. P., Mar 1 2008, In : Obstetrics and gynecology. 111, 3, p. 589-595 7 p.

Research output: Contribution to journalArticle

Open Access
125 Scopus citations
2004

Alpha-1-antitrypsin deficiency: Diagnosis and treatment

Perlmutter, D. H., Nov 1 2004, In : Clinics in Liver Disease. 8, 4, p. 839-859 21 p.

Research output: Contribution to journalReview article

61 Scopus citations
2003

An outbreak of Pseudomonas aeruginosa infections associated with flexible bronchoscopes

Srinivasan, A., Wolfenden, L. L., Song, X., Mackie, K., Hartsell, T. L., Jones, H. D., Diette, G. B., Orens, J. B., Yung, R. C., Ross, T. L., Merz, W., Scheel, P. J., Haponik, E. F. & Perl, T. M., Jan 16 2003, In : New England Journal of Medicine. 348, 3, p. 221-227 7 p.

Research output: Contribution to journalArticle

151 Scopus citations

Spontaneous renal artery dissection: Treatment with coil embolization

Mudrick, D., Arepally, A., Geschwind, J. F., Ronsivalle, J. A., Lund, G. B. & Scheel, P., Apr 1 2003, In : Journal of Vascular and Interventional Radiology. 14, 4, p. 497-500 4 p.

Research output: Contribution to journalArticle

25 Scopus citations
2002
29 Scopus citations

Chemical chaperones: A pharmacological strategy for disorders of protein folding and trafficking

Perlmutter, D. H., Dec 2002, In : Pediatric research. 52, 6, p. 832-836 5 p.

Research output: Contribution to journalReview article

Open Access
191 Scopus citations

Extrahepatic biliary atresia: A disease or a phenotype?

Perlmutter, D. H. & Shepherd, R. W., Jun 2002, In : Hepatology. 35, 6, p. 1297-1304 8 p.

Research output: Contribution to journalArticle

107 Scopus citations

Fasting in α1-antitrypsin deficient liver: Consultative activation of autophagy

Teckman, J. H., An, J. K., Loethen, S. & Perlmutter, D. H., Nov 2002, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 283, 5 46-5, p. G1156-G1165

Research output: Contribution to journalArticle

64 Scopus citations

Liver injury in α1-antitrypsin deficiency: An aggregated protein induces mitochondrial injury

Perlmutter, D. H., Dec 2002, In : Journal of Clinical Investigation. 110, 11, p. 1579-1583 5 p.

Research output: Contribution to journalReview article

Open Access
144 Scopus citations
2001

A Naturally Occurring Nonpolymerogenic Mutant of α1-Antitrypsin Characterized by Prolonged Retention in the Endoplasmic Reticulum

Lin, L., Schmidt, B., Teckman, J. & Perlmutter, D. H., Sep 7 2001, In : Journal of Biological Chemistry. 276, 36, p. 33893-33898 6 p.

Research output: Contribution to journalArticle

Open Access
48 Scopus citations

Outcome of early hepatic portoenterostomy for biliary atresia

Volpert, D., White, F., Finegold, M. J., Molleston, J., DeBaun, M. & Perlmutter, D. H., May 7 2001, In : Journal of pediatric gastroenterology and nutrition. 32, 3, p. 265-269 5 p.

Research output: Contribution to journalArticle

36 Scopus citations
Open Access
120 Scopus citations
2000

Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells

Uemura, Y., Pak, S. C., Luke, C., Çataltepe, S., Tsu, C., Schick, C., Kamachi, Y., Pomeroy, S. L., Perlmutter, D. H. & Silverman, G. A., Jul 20 2000, In : International Journal of Cancer. 89, 4, p. 368-377 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

Cohort study of the treatment of severe HIV-associated nephropathy with corticosteroids

Eustace, J. A., Nuermberger, E., Choi, M., Scheel, J., Moore, R. & Briggs, W. A., Jan 1 2000, In : Kidney International. 58, 3, p. 1253-1260 8 p.

Research output: Contribution to journalArticle

Open Access
109 Scopus citations

Glucosidase and mannosidase inhibitors mediate increased secretion of mutant α1 antitrypsin Z

Marcus, N. Y. & Perlmutter, D. H., Jan 21 2000, In : Journal of Biological Chemistry. 275, 3, p. 1987-1992 6 p.

Research output: Contribution to journalArticle

Open Access
66 Scopus citations

Liver injury in alpha1-antitrypsin deficiency

Perlmutter, D. H., Jan 1 2000, In : Clinics in Liver Disease. 4, 2, p. 387-408 22 p.

Research output: Contribution to journalArticle

25 Scopus citations

Relationship between lymphocyte and clinical steroid responsiveness in focal segmental glomerulosclerosis

Briggs, W. A., Gimenez, L. E., Samaniego-Picota, M., Choi, M. J., Nadasdy, T., Eustace, J. & Scheel, P. J., Jan 1 2000, In : Journal of clinical pharmacology. 40, 2, p. 115-123 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
225 Scopus citations
61 Scopus citations

α1-antitrypsin deficiency-associated liver disease progresses slowly in some children

Volpert, D., Molleston, J. P. & Perlmutter, D. H., Sep 14 2000, In : Journal of pediatric gastroenterology and nutrition. 31, 3, p. 258-263 6 p.

Research output: Contribution to journalArticle

35 Scopus citations
1999

Anomalous development of the hepatobiliary system in the inv mouse

Mazziotti, M. V., Willis, L. K., Heuckeroth, R. O., LaRegina, M. C., Swanson, P. E., Overbeek, P. A. & Perlmutter, D. H., Aug 9 1999, In : Hepatology. 30, 2, p. 372-378 7 p.

Research output: Contribution to journalArticle

Open Access
95 Scopus citations

Chain length of the polylysine in receptor-targeted gene transfer complexes affects duration of reporter gene expression both in vitro and in vivo

Ziady, A. G., Ferkol, T., Dawson, D. V., Perlmutter, D. H. & Davis, P. B., Feb 19 1999, In : Journal of Biological Chemistry. 274, 8, p. 4908-4916 9 p.

Research output: Contribution to journalArticle

Open Access
67 Scopus citations

Disruption of disulfide bonds is responsible for impaired secretion in human complement factor H deficiency

Schmidt, B. Z., Fowler, N. L., Hidvegi, T., Perlmutter, D. H. & Colten, H. R., Apr 23 1999, In : Journal of Biological Chemistry. 274, 17, p. 11782-11788 7 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Misfolded proteins in the endoplasmic reticulum

Perlmutter, D. H., Jun 1 1999, In : Laboratory Investigation. 79, 6, p. 623-638 16 p.

Research output: Contribution to journalReview article

47 Scopus citations

Primary gastric plasmacytoma: A rare cause of hypertrophic gastritis in an adolescent

Goyal, A., Langer, J. C., Zutter, M., Swanson, P., Kraus, M. D., Bartlett, N., Shackelford, G. D., Longtine, J. A. & Perlmutter, D. H., Oct 1 1999, In : Journal of pediatric gastroenterology and nutrition. 29, 4, p. 424-430 7 p.

Research output: Contribution to journalArticle

12 Scopus citations