School of Medicine Vice Chancellor's Office

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    Research Output

    Mechanisms of action of autophagy modulators dissected by quantitative systems pharmacology analysis

    Shi, Q., Pei, F., Silverman, G. A., Pak, S. C., Perlmutter, D. H., Liu, B. & Bahar, I., Apr 1 2020, In : International journal of molecular sciences. 21, 8, 2855.

    Research output: Contribution to journalArticle

    Open Access
  • An analog of glibenclamide selectively enhances autophagic degradation of misfolded α1-antitrypsin Z

    Wang, Y., Cobanoglu, M. C., Li, J., Hidvegi, T., Hale, P., Ewing, M., Chu, A. S., Gong, Z., Muzumdar, R., Pak, S. C., Silverman, G. A., Bahar, I. & Perlmutter, D. H., Jan 2019, In : PloS one. 14, 1, e0209748.

    Research output: Contribution to journalArticle

    Open Access
  • 3 Scopus citations

    NFκB mitigates the pathological effects of misfolded α1-antitrypsin by activating autophagy and an integrated program of proteostasis mechanisms

    Mukherjee, A., Hidvegi, T., Araya, P., Ewing, M., Stolz, D. B. & Perlmutter, D. H., Mar 1 2019, In : Cell Death and Differentiation. 26, 3, p. 455-469 15 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations