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2020

Barrier-to-autointegration factor 1 protects against a basal cGAS-STING response

Ma, H., Qian, W., Bambouskova, M., Collins, P. L., Porter, S. I., Byrum, A. K., Zhang, R., Artyomov, M., Oltz, G., Mosammaparast, N., Miner, J. J. & Diamond, M. S., Mar 1 2020, In : mBio. 11, 2, e00136-20.

Research output: Contribution to journalArticle

Open Access

Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis

Mack, M. R., Brestoff, J. R., Berrien-Elliott, M. M., Trier, A. M., Yang, T. L. B., McCullen, M., Collins, P. L., Niu, H., Bodet, N. D., Wagner, J. A., Park, E., Xu, A. Z., Wang, F., Chibnall, R., Council, M. L., Heffington, C., Kreisel, F., Margolis, D. J., Sheinbein, D., Lovato, P. & 7 others, Vivier, E., Cella, M., Colonna, M., Yokoyama, W. M., Oltz, G., Fehniger, T. A. & Kim, B. S., Feb 26 2020, In : Science translational medicine. 12, 532, aay1005.

Research output: Contribution to journalArticle

7 Scopus citations

cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity

Ferris, S. T., Durai, V., Wu, R., Theisen, D. J., Ward, J. P., Bern, M. D., Davidson, J. T., Bagadia, P., Liu, T., Briseño, C. G., Li, L., Gillanders, W., Wu, G. F., Yokoyama, W. M., Murphy, T. L., Schreiber, R. D. & Murphy, K. M., Aug 27 2020, In : Nature. 584, 7822, p. 624-629 6 p.

Research output: Contribution to journalArticle

Choroidal thickness in lupus nephritis

Lee, I., Marshall, B., Ranganathan, P., Eisen, S., Rajagopal, R., Kim, A. H. J. & Li, T., Feb 1 2020, In : Lupus. 29, 2, p. 205-209 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Control of Viral Infection by Natural Killer Cell Inhibitory Receptors

Parikh, B., Bern, M. D., Piersma, S., Yang, L., Beckman, D. L., Poursine-Laurent, J., Plougastel-Douglas, B. & Yokoyama, W. M., Jul 28 2020, In : Cell Reports. 32, 4, 107969.

Research output: Contribution to journalArticle

Open Access

Distinct roles of interferon alpha and beta in controlling chikungunya virus replication and modulating neutrophil-mediated inflammation

Cook, L. E., Locke, M. C., Young, A. R., Monte, K., Hedberg, M. L., Shimak, R. M., Sheehan, K. C. F., Veis, D. J., Diamond, M. S. & Lenschow, D. J., Jan 1 2020, In : Journal of virology. 94, 1, e00841-19.

Research output: Contribution to journalArticle

9 Scopus citations

Examining Relations Between Obsessive-Compulsive Features, Substance-Use Disorders, and Antisocial Personality Disorder in the Vietnam Era Twin Cohort

Williams, M., Baskin-Sommers, A. R., Xian, H., Wirth, L., Scherrer, J. F., Volberg, R. A., Slutske, W. S., Kraus, S. W., Eisen, S. A. & Potenza, M. N., Jan 1 2020, (Accepted/In press) In : International Journal of Mental Health and Addiction.

Research output: Contribution to journalArticle

Goblet cell associated antigen passages support the induction and maintenance of oral tolerance

Kulkarni, D. H., Gustafsson, J. K., Knoop, K. A., McDonald, K. G., Bidani, S. S., Davis, J. E., Floyd, A. N., Hogan, S. P., Hsieh, C. S. & Newberry, R. D., Mar 1 2020, In : Mucosal Immunology. 13, 2, p. 271-282 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Impaired tumor necrosis factor-α secretion by CD4 T cells during respiratory syncytial virus bronchiolitis associated with recurrent wheeze

Kitcharoensakkul, M., Bacharier, L. B., Yin-Declue, H., Boomer, J. S., Sajol, G., Leung, M. K., Wilson, B., Schechtman, K. B., Atkinson, J. P., Green, J. & Castro, M., Mar 1 2020, In : Immunity, Inflammation and Disease. 8, 1, p. 30-39 10 p.

Research output: Contribution to journalArticle

Open Access

Induction of WNT16 via peptide-mRNA nanoparticle-based delivery maintains cartilage homeostasis

Yan, H., Hu, Y., Akk, A., Rai, M. F., Pan, H., Wickline, S. A. & Pham, C. T. N., Jan 2020, In : Pharmaceutics. 12, 1, 73.

Research output: Contribution to journalArticle

Open Access

Longitudinal associations between depressive symptoms and clinical factors in ankylosing spondylitis patients: analysis from an observational cohort

Hwang, M. C., Lee, M. J., Gensler, L. S., Ward, M. M., Brown, M. A., Eisen, S., Learch, T. J., Tahanan, A., Rahbar, M. H., Ishimori, M. L., Weisman, M. H. & Reveille, J. D., Jul 1 2020, In : Rheumatology International. 40, 7, p. 1053-1061 9 p.

Research output: Contribution to journalArticle

Patient and physician discordance of global disease assessment in juvenile dermatomyositis: Findings from the Childhood Arthritis & Rheumatology Research Alliance Legacy Registry

Tory, H., Zurakowski, D., Kim, S., Abramson, L., Anderson, E., Andrew, M., Battle, N., Becker, M., Benham, H., Beukelman, T., Birmingham, J., Blier, P., Brown, A., Brunner, H., Cabrera, A., Canter, D., Carlton, D., Caruso, B., Ceracchio, L., Chalom, E. & 102 others, Chang, J., Charpentier, P., Clark, K., Dean, J., Dedeoglu, F., Feldman, B., Ferguson, P., Fox, M., Francis, K., Gervasini, M., Goldsmith, D., Gorton, G., Gottlieb, B., Graham, T., Griffin, T., Grosbein, H., Guppy, S., Haftel, H., Helfrich, D., Higgins, G., Hillard, A., Hollister, J. R., Hsu, J., Hudgins, A., Hung, C., Huttenlocher, A., Ilowite, N., Imlay, A., Imundo, L., Inman, C. J., Jaqith, J., Jerath, R., Jung, L., Kahn, P., Kapedani, A., Kingsbury, D., Klein, K., Klein-Gitelman, M., Kunkel, A., Lapidus, S., Layburn, S., Lehman, T., Lindsley, C., Macgregor-Hannah, M., Malloy, M., Mawhorter, C., McCurdy, D., Mims, K., Moorthy, N., Morus, D., Muscal, E., Natter, M., Olson, J., O'Neil, K., Onel, K., Orlando, M., Palmquist, J., Phillips, M., Ponder, L., Prahalad, S., Punaro, M., Puplava, D., Quinn, S., Quintero, A., Rabinovich, C., Reed, A., Reed, C., Ringold, S., Riordan, M., Roberson, S., Robinson, A., Rossette, J., Rothman, D., Russo, D., Ruth, N., Schikler, K., Sestak, A., Shaham, B., Sherman, Y., Simmons, M., Singer, N., Spalding, S., Stapp, H., Syed, R., Thomas, E., Torok, K., Trejo, D., Tress, J., Upton, W., Vehe, R., Von Scheven, E., Walters, L., Weiss, J., Weiss, P., Welnick, N., White, A., Woo, J., Wootton, J., Yalcindag, A., Zapp, C., Zemel, L. & Zhu, A., Jan 15 2020, In : Pediatric Rheumatology. 18, 1, 5.

Research output: Contribution to journalArticle

Open Access

STING Gain-of-Function Disrupts Lymph Node Organogenesis and Innate Lymphoid Cell Development in Mice

Bennion, B. G., Croft, C. A., Ai, T. L., Qian, W., Menos, A. M., Miner, C. A., Frémond, M. L., Doisne, J. M., Andhey, P. S., Platt, D. J., Bando, J. K., Wang, E. R., Luksch, H., Molina, T. J., Roberson, E., Artomov, M., Rösen-Wolff, A., Colonna, M., Rieux-Laucat, F., Di Santo, J. P. & 2 others, Neven, B. & Miner, J. J., Jun 16 2020, In : Cell Reports. 31, 11, 107771.

Research output: Contribution to journalArticle

Open Access

Swinging the pendulum: lessons learned from public discourse concerning hydroxychloroquine and COVID-19

Sattui, S. E., Liew, J. W., Graef, E. R., Coler-Reilly, A., Berenbaum, F., Duarte-García, A., Harrison, C., Konig, M. F., Korsten, P., Putman, M. S., Robinson, P. C., Sirotich, E., Ugarte-Gil, M. F., Webb, K., Young, K. J., Kim, A. H. J. & Sparks, J. A., 2020, In : Expert Review of Clinical Immunology.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Synchronization of mothers and offspring promotes tolerance and limits allergy

Knoop, K. A., McDonald, K. G., Coughlin, P. E., Kulkarni, D. H., Gustafsson, J. K., Rusconi, B., John, V., Ndao, I. M., Beigelman, A., Good, M., Warner, B. B., Elson, C. O., Hsieh, C. S., Hogan, S. P., Tarr, P. I. & Newberry, R., Aug 6 2020, In : JCI Insight. 5, 15

Research output: Contribution to journalArticle

Open Access

TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells

Balka, K. R., Louis, C., Saunders, T. L., Smith, A. M., Calleja, D. J., D'Silva, D. B., Moghaddas, F., Tailler, M., Lawlor, K. E., Zhan, Y., Burns, C. J., Wicks, I. P., Miner, J. J., Kile, B. T., Masters, S. L. & De Nardo, D., Apr 7 2020, In : Cell Reports. 31, 1, 107492.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

T cell response kinetics determines neuroinfection outcomes during murine HSV infection

Lee, A. G., Scott, J. M., Fabbrizi, M. R., Jiang, X., Sojka, D. K., Miller, M. J., Baldridge, M. T., Yokoyama, W. M. & Shin, H., Mar 12 2020, In : JCI Insight. 5, 5, e134258.

Research output: Contribution to journalArticle

Open Access

Validation of a commercial antibody to detect endogenous human nicastrin by immunoblot

Roberson, E. D. O. & Mesa, R. A., Jan 1 2020, In : F1000Research. 8, 1211.

Research output: Contribution to journalArticle

Open Access

Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING

Piersma, S., Poursine-Laurent, J., Yang, L., Barber, G. N., Parikh, B. & Yokoyama, W. M., Jul 29 2020, In : eLife. 9

Research output: Contribution to journalArticle

Open Access
2019

A catalog of CasX genome editing sites in common model organisms

Roberson, E. D. O., Jun 27 2019, In : BMC genomics. 20, 1, 528.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

A human gain-of-function STING mutation causes immunodeficiency and gammaherpesvirus-induced pulmonary fibrosis in mice

Bennion, B. G., Ingle, H., Ai, T. L., Miner, C. A., Platt, D. J., Smith, A. M., Baldridge, M. T. & Miner, J. J., Feb 1 2019, In : Journal of virology. 93, 4, e0180618.

Research output: Contribution to journalArticle

6 Scopus citations

A Human STAT1 Gain-of-Function Mutation Impairs CD8+ T Cell Responses against Gammaherpesvirus 68

Qian, W., Miner, C. A., Ingle, H., Platt, D. J., Baldridge, M. T. & Miner, J. J., Oct 1 2019, In : Journal of virology. 93, 19

Research output: Contribution to journalArticle

A Multimodality Approach to Assessing Factor I Genetic Variants in Atypical Hemolytic Uremic Syndrome

Java, A., Pozzi, N., Love-Gregory, L. D., Heusel, J. W., Sung, Y. J., Hu, Z., Bertram, P., Liszewski, M. K., Cline, L. M., Ren, Z. & Atkinson, J. P., Jul 2019, In : Kidney International Reports. 4, 7, p. 1007-1017 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Association of Blood Concentrations of Complement Split Product iC3b and Serum C3 With Systemic Lupus Erythematosus Disease Activity

Kim, A. H. J., Strand, V., Sen, D. P., Fu, Q., Mathis, N. L., Schmidt, M. J., Bruchas, R. R., Staten, N. R., Olson, P. K., Stiening, C. M. & Atkinson, J. P., Mar 2019, In : Arthritis and Rheumatology. 71, 3, p. 420-430 11 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Association of Short-Term Ultraviolet Radiation Exposure and Disease Severity in Juvenile Dermatomyositis: Results From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry

for the Childhood Arthritis and Rheumatology Research Alliance Registry Investigators, Dec 1 2019, In : Arthritis Care and Research. 71, 12, p. 1600-1605 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Bronchus-associated lymphoid tissue–resident Foxp3 + T lymphocytes prevent antibody-mediated lung rejection

Li, W., Gauthier, J. M., Higashikubo, R., Hsiao, H. M., Tanaka, S., Vuong, L., Ritter, J. H., Tong, A. Y., Wong, B. W., Hachem, R. R., Puri, V., Bharat, A., Krupnick, A. S., Hsieh, C. S., Baldwin, W. M., Kelly, F. L., Palmer, S. M., Gelman, A. E. & Kreisel, D., Feb 1 2019, In : Journal of Clinical Investigation. 129, 2, p. 556-568 13 p.

Research output: Contribution to journalArticle

16 Scopus citations
Open Access
1 Scopus citations

Complement activation on neutrophils initiates endothelial adhesion and extravasation

Akk, A., Springer, L. E., Yang, L., Hamilton-Burdess, S., Lambris, J. D., Yan, H., Hu, Y., Wu, X., Hourcade, D. E., Miller, M. J. & Pham, C. T. N., Oct 2019, In : Molecular Immunology. 114, p. 629-642 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
3 Scopus citations

Cowpox virus encodes a protein that binds B7.1 and B7.2 and subverts T cell costimulation

Wang, X., Piersma, S. J., Elliott, J. I., Errico, J. M., Gainey, M. D., Yang, L., Nelson, C. A., Yokoyama, W. M. & Fremont, D. H., Oct 15 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 42, p. 21113-21119 7 p.

Research output: Contribution to journalArticle

Open Access
Open Access
3 Scopus citations

Development of a peptide-siRNA nanocomplex targeting NF- κB for efficient cartilage delivery

Yan, H., Duan, X., Pan, H., Akk, A., Sandell, L. J., Wickline, S. A., Rai, M. F. & Pham, C. T. N., Dec 1 2019, In : Scientific reports. 9, 1, 442.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Fat-Produced Adipsin Regulates Inflammatory Arthritis

Li, Y., Zou, W., Brestoff, J. R., Rohatgi, N., Wu, X., Atkinson, J. P., Harris, C. A. & Teitelbaum, S. L., Jun 4 2019, In : Cell Reports. 27, 10, p. 2809-2816.e3

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Gardnerella vaginalis and Prevotella bivia Trigger Distinct and Overlapping Phenotypes in a Mouse Model of Bacterial Vaginosis

Gilbert, N. M., Lewis, W. G., Li, G., Sojka, D. K., Lubin, J. B. & Lewis, A. L., Aug 30 2019, In : Journal of Infectious Diseases. 220, 7, p. 1099-1108 10 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis

Ardain, A., Domingo-Gonzalez, R., Das, S., Kazer, S. W., Howard, N. C., Singh, A., Ahmed, M., Nhamoyebonde, S., Rangel-Moreno, J., Ogongo, P., Lu, L., Ramsuran, D., de la Luz Garcia-Hernandez, M., K. Ulland, T., Darby, M., Park, E., Karim, F., Melocchi, L., Madansein, R., Dullabh, K. J. & 16 others, Dunlap, M., Marin-Agudelo, N., Ebihara, T., Ndung’u, T., Kaushal, D., Pym, A. S., Kolls, J. K., Steyn, A., Zúñiga, J., Horsnell, W., Yokoyama, W. M., Shalek, A. K., Kløverpris, H. N., Colonna, M., Leslie, A. & Khader, S. A., Jun 27 2019, In : Nature. 570, 7762, p. 528-532 5 p.

Research output: Contribution to journalArticle

34 Scopus citations

Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice

Smith-Jackson, K., Yang, Y., Denton, H., Pappworth, I. Y., Cooke, K., Barlow, P. N., Atkinson, J. P., Kathryn Liszewski, M., Pickering, M. C., Kavanagh, D., Terence Cook, H. & Marchbank, K. J., Mar 2019, In : Journal of Clinical Investigation. 129, 3, p. 1061-1075 15 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Interleukin-12 and -23 blockade mitigates elastase-induced abdominal aortic aneurysm

Yan, H., Hu, Y., Akk, A., Ye, K., Bacon, J. & Pham, C. T. N., Dec 1 2019, In : Scientific reports. 9, 1, 10447.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

In the absence of natural killer cell activation donor-specific antibody mediates chronic, but not acute, kidney allograft rejection

Yagisawa, T., Tanaka, T., Miyairi, S., Tanabe, K., Dvorina, N., Yokoyama, W. M., Valujskikh, A., Baldwin, W. M. & Fairchild, R. L., Feb 2019, In : Kidney International. 95, 2, p. 350-362 13 p.

Research output: Contribution to journalArticle

4 Scopus citations
7 Scopus citations

Long-term correction of hemophilia B using adenoviral delivery of CRISPR/Cas9

Stephens, C. J., Lauron, E. J., Kashentseva, E., Lu, Z. H., Yokoyama, W. M. & Curiel, D. T., Mar 28 2019, In : Journal of Controlled Release. 298, p. 128-141 14 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Medical Correlates of Chronic Multisymptom Illness in Gulf War Veterans

Blanchard, M., Molina-Vicenty, H. D., Stein, P. K., Li, X., Karlinsky, J., Alpern, R., Reda, D. J. & Toomey, R., Apr 2019, In : American Journal of Medicine. 132, 4, p. 510-518 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mental health in spouses of U.S. Gulf War veterans

Toomey, R., Alpern, R., Reda, D. J., Baker, D. G., Vasterling, J. J., Blanchard, M. & Eisen, S. A., May 2019, In : Psychiatry Research. 275, p. 287-295 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Mucosal infection rewires TNFα signaling dynamics to skew susceptibility to recurrence

Yu, L., O’Brien, V. P., Livny, J., Dorsey, D., Bandyopadhyay, N., Colonna, M., Caparon, M. G., Roberson, E. D. O., Hultgren, S. J. & Hannan, T. J., Aug 2019, In : eLife. 8, e46677.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Neutrophil Cathepsin G and Tumor Cell RAGE Facilitate Neutrophil Anti-Tumor Cytotoxicity

Sionov, R. V., Fainsod-Levi, T., Zelter, T., Polyansky, L., Pham, C. T. & Granot, Z., Sep 2 2019, In : OncoImmunology. 8, 9, e1624129.

Research output: Contribution to journalArticle

3 Scopus citations

Neutrophils promote VLA-4–dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation

Parker Harp, C. R., Archambault, A. S., Cheung, M., Williams, J. W., Czepielewski, R. S., Duncker, P. C., Kilgore, A. J., Miller, A. T., Segal, B. M., Kim, A. H. J., Randolph, G. J. & Wu, G. F., Nov 26 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 48, p. 24221-24230 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
8 Scopus citations

Pain, functional disability, and their Association in Juvenile Fibromyalgia Compared to other pediatric rheumatic diseases

Connelly, M., Weiss, J. E., Abramson, L., Anderson, E., Andrew, M., Battle, N., Becker, M., Benham, H., Beukelman, T., Birmingham, J., Blier, P., Brown, A., Brunner, H., Cabrera, A., Canter, D., Carlton, D., Caruso, B., Ceracchio, L., Chalom, E., Chang, J. & 101 others, Charpentier, P., Clark, K., Dean, J., Dedeoglu, F., Feldman, B., Ferguson, P., Fox, M., Francis, K., Gervasini, M., Goldsmith, D., Gorton, G., Gottlieb, B., Graham, T., Griffin, T., Grosbein, H., Guppy, S., Haftel, H., Helfrich, D., Higgins, G., Hillard, A., Hollister, J. R., Hsu, J., Hudgins, A., Hung, C., Huttenlocher, A., Ilowite, N., Imlay, A., Imundo, L., Inman, C. J., Jaqith, J., Jerath, R., Jung, L., Kahn, P., Kapedani, A., Kingsbury, D., Klein, K., Klein-Gitelman, M., Kunkel, A., Lapidus, S., Layburn, S., Lehman, T., Lindsley, C., MacGregorhannah, M., Malloy, M., Mawhorter, C., McCurdy, D., Mims, K., Moorthy, N., Morus, D., Muscal, E., Natter, M., Olson, J., O'Neil, K., Onel, K., Orlando, M., Palmquist, J., Phillips, M., Ponder, L., Prahalad, S., Punaro, M., Puplava, D., Quinn, S., Quintero, A., Rabinovich, C., Reed, A., Reed, C., Ringold, S., Riordan, M., Roberson, S., Robinson, A., Rossette, J., Rothman, D., Russo, D., Ruth, N., Schikler, K., Sestak, A., Shaham, B., Sherman, Y., Simmons, M., Singer, N., Spalding, S., Stapp, H., Syed, R., Thomas, E., Torok, K., Trejo, D., Tress, J., Upton, W., Vehe, R., Von Scheven, E., Walters, L., Weiss, J., Weiss, P., Welnick, N., White, A., Woo, J., Wootton, J., Yalcindag, A., Zapp, C., Zemel, L. & Zhu, A., Nov 6 2019, In : Pediatric Rheumatology. 17, 1, 72.

Research output: Contribution to journalArticle

Open Access

Rare mutations in the complement regulatory gene CSMD1 are associated with male and female infertility

Lee, A. S., Rusch, J., Lima, A. C., Usmani, A., Huang, N., Lepamets, M., Vigh-Conrad, K. A., Worthington, R. E., Mägi, R., Wu, X., Aston, K. I., Atkinson, J. P., Carrell, D. T., Hess, R. A., O’Bryan, M. K. & Conrad, D. F., Dec 1 2019, In : Nature communications. 10, 1, 4626.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations