Rheumatic Diseases Research Resource-Based Center

Research output

Research output per year 1946 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 5936 Article
• 681 Review article
• 225 Comment/debate
• 147 Letter
• 419 More
  • 132 Chapter
  • 131 Editorial
  • 69 Short survey
  • 63 Conference contribution
  • 8 Paper
  • 8 Conference article
  • 4 Book
  • 4 Foreword/postscript

Research output per year

Research output per year

Search results

• 2022

  MPN-075 Efficacy and Safety of Add-on Parsaclisib to Ruxolitinib Therapy in Myelofibrosis Patients With Low Versus Higher Baseline Platelet Counts: A Subgroup Analysis of Data From a Phase 2 Study

  Yacoub, A., Borate, U., Rampal, R., Ali, H., Wang, E., Gerds, A., Hobbs, G., Kremyanskaya, M., Winton, E., O'Connell, C., Goel, S., Oh, S., Schiller, G., Assad, A., Erickson-Viitanen, S., Zhou, F. & Daver, N., Oct 2022, In: Clinical Lymphoma, Myeloma and Leukemia. 22, p. S324

  Research output: Contribution to journal › Article › peer-review

  • INCB018424 100%
  • Primary Myelofibrosis 80%
  • Platelet Count 62%
  • Data Analysis 48%
  • Safety 37%

• MPN-103 A Real-World Evaluation of the Association Between Elevated Blood Counts and Thrombotic Events in Polycythemia Vera: Analysis of Data From the REVEAL Study

  Gerds, A. T., Mesa, R., Burke, J. M., Grunwald, M. R., Scherber, R., Yu, J., Hamer-Maansson, J. E. & Oh, S. T., Oct 2022, In: Clinical Lymphoma, Myeloma and Leukemia. 22, p. S326

  Research output: Contribution to journal › Article › peer-review

  • Polycythemia Vera 100%
  • Data Analysis 57%
  • Leukocyte Count 54%
  • Hematocrit 35%
  • Platelet Count 27%

• MPN-141 Retrospective Comparison of Patient Outcomes on Pacritinib Versus Ruxolitinib in Patients With Myelofibrosis and Thrombocytopenia

  Harrison, C., Bose, P., Mesa, R., Gerds, A., Oh, S., Kiladijan, J. J., Garcia-Gutierrez, V., Vannucchi, A., Scheid, C., Sobas, M., Verstovsek, S., Buckley, S., Roman-Torres, K. & Mascarenhas, J., Oct 2022, In: Clinical Lymphoma, Myeloma and Leukemia. 22, p. S326-S327

  Research output: Contribution to journal › Article › peer-review

  • 11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene 100%
  • INCB018424 78%
  • Primary Myelofibrosis 63%
  • Thrombocytopenia 47%
  • Platelet Count 11%

• MPN-145 Retrospective Analysis of Anemia Benefit of Pacritinib From the PERSIST-2 Trial

  Oh, S., Mesa, R., Harrison, C., Bose, P., Gerds, A., Gupta, V., Swami, A., Tyavanagimatt, S., Buckley, S., Roman-Torres, K. & Verstovsek, S., Oct 2022, In: Clinical Lymphoma, Myeloma and Leukemia. 22, p. S327

  Research output: Contribution to journal › Article › peer-review

  • 11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene 100%
  • Anemia 42%
  • N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide 13%
  • Inhibitory Concentration 50 9%
  • Primary Myelofibrosis 8%
  1 Scopus citations

• MPN-238 Single-Cell RNA Profiling of Myelofibrosis Patients Reveals Pelabresib-Induced Decrease of Megakaryocytic Progenitors and Normalization of CD4+ T Cells in Peripheral Blood

  Zavidij, O., Haradhvala, N. J., Meyer, R., Cui, J., Verstovsek, S., Oh, S., Mead, A. & Taverna, P., Oct 2022, In: Clinical Lymphoma, Myeloma and Leukemia. 22, p. S331-S332

  Research output: Contribution to journal › Article › peer-review

  • Primary Myelofibrosis 100%
  • INCB018424 78%
  • RNA 55%
  • T-Lymphocytes 49%
  • CPI-0610 17%

• mRNA-1273 and Ad26.COV2.S vaccines protect against the B.1.621 variant of SARS-CoV-2

  Darling, T. L., Ying, B., Whitener, B., VanBlargan, L. A., Bricker, T. L., Liang, C. Y., Joshi, A., Bamunuarachchi, G., Seehra, K., Schmitz, A. J., Halfmann, P. J., Kawaoka, Y., Elbashir, S. M., Edwards, D. K., Thackray, L. B., Diamond, M. S. & Boon, A. C. M., May 13 2022, In: Med. 3, 5, p. 309-324.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Vaccines 58%
  • National Institute of Allergy and Infectious Diseases (U.S.) 47%
  • Messenger RNA 44%
  1 Scopus citations

• mRNA vaccine boosting enhances antibody responses against SARS-CoV-2 Omicron variant in individuals with antibody deficiency syndromes

  Zimmerman, O., Altman Doss, A. M., Kaplonek, P., Liang, C. Y., VanBlargan, L. A., Chen, R. E., Monroy, J. M., Wedner, H. J., Kulczycki, A., Mantia, T. L., O'Shaughnessy, C. C., Davis-Adams, H. G., Bertera, H. L., Adams, L. J., Raju, S., Zhao, F. R., Rigell, C., Dy, T. B., Kau, A. L., Ren, Z., & 8 othersTurner, J. S., O'Halloran, J. A., Presti, R. M., Fremont, D. H., Kendall, P. L., Ellebedy, A. H., Alter, G. & Diamond, M. S., Jun 21 2022, In: Cell Reports Medicine. 3, 6, 100653.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Immunologic Deficiency Syndromes 100%
  • Primary Immunodeficiency Diseases 75%
  • Severe Acute Respiratory Syndrome 71%
  • Coronavirus 69%
  • Antibody Formation 49%
  6 Scopus citations

• Multiparameter analysis of human B lymphocytes identifies heterogeneous CD19⁺CD21^lo subsets

  Wilfong, E. M., Vowell, K. N., Crofford, L. J. & Kendall, P. L., 2022, (Accepted/In press) In: Cytometry Part A.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • B-Lymphocytes 100%
  • B-Lymphocyte Subsets 72%
  • Flow Cytometry 22%
  • Down-Regulation 20%
  • Healthy Volunteers 9%

• Multiplatform Single-Cell Analysis Identifies Immune Cell Types Enhanced in Pulmonary Fibrosis

  Serezani, A. P. M., Pascoalino, B. D., Bazzano, J. M. R., Vowell, K. N., Tanjore, H., Taylor, C. J., Calvi, C. L., McCall, A. S., Bacchetta, M. D., Shaver, C. M., Ware, L. B., Salisbury, M. L., Banovich, N. E., Kendall, P. L., Kropski, J. A. & Blackwell, T. S., Jul 2022, In: American Journal of Respiratory Cell and Molecular Biology. 67, 1, p. 50-60 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Single-Cell Analysis 100%
  • Idiopathic Pulmonary Fibrosis 89%
  • Pulmonary Fibrosis 85%
  • Effector 81%
  • RNA Sequencing 61%
  7 Scopus citations

• Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice

  Hunt, A. C., Case, J. B., Park, Y. J., Cao, L., Wu, K., Walls, A. C., Liu, Z., Bowen, J. E., Yeh, H. W., Saini, S., Helms, L., Zhao, Y. T., Hsiang, T. Y., Starr, T. N., Goreshnik, I., Kozodoy, L., Carter, L., Ravichandran, R., Green, L. B., Matochko, W. L., & 27 othersThomson, C. A., Vögeli, B., Krüger, A., VanBlargan, L. A., Chen, R. E., Ying, B., Bailey, A. L., Kafai, N. M., Boyken, S. E., Ljubetiè, A., Edman, N., Ueda, G., Chow, C. M., Johnson, M., Addetia, A., Navarro, M. J., Panpradist, N., Gale, M., Freedman, B. S., Bloom, J. D., Ruohola-Baker, H., Whelan, S. P. J., Stewart, L., Diamond, M. S., Veesler, D., Jewett, M. C. & Baker, D., May 25 2022, In: Science translational medicine. 14, 646

  Research output: Contribution to journal › Article › peer-review

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Infections 37%
  • Proteins 28%
  • angiotensin converting enzyme 2 23%
  20 Scopus citations

• Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains

  Bigley, T. M., Xiong, M., Ali, M., Chen, Y., Wang, C., Serrano, J. R., Eteleeb, A., Harari, O., Yang, L., Patel, S. J., Cruchaga, C., Yokoyama, W. M. & Holtzman, D. M., Dec 2022, In: Molecular neurodegeneration. 17, 1, 10.

  Research output: Contribution to journal › Article › peer-review

  • Roseolovirus 100%
  • Amyloid 52%
  • Alzheimer Disease 43%
  • Pathology 35%
  • Roseolovirus Infections 29%
  3 Scopus citations

• Myeloproliferative Neoplasms, Version 3.2022

  Gerds, A. T., Gotlib, J., Ali, H., Bose, P., Dunbar, A., Elshoury, A., George, T. I., Gundabolu, K., Hexner, E., Hobbs, G. S., Jain, T., Jamieson, C., Kaesberg, P. R., Kuykendall, A. T., Madanat, Y., McMahon, B., Mohan, S. R., Nadiminti, K. V., Oh, S., Pardanani, A., & 11 othersPodoltsev, N., Rein, L., Salit, R., Stein, B. L., Talpaz, M., Vachhani, P., Wadleigh, M., Wall, S., Ward, D. C., Bergman, M. A. & Hochstetler, C., Sep 2022, In: JNCCN Journal of the National Comprehensive Cancer Network. 20, 9, p. 1033-1062 30 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Essential Thrombocythemia 100%
  • Polycythemia Vera 96%
  • Guidelines 47%
  • Philadelphia Chromosome 47%
  • Primary Myelofibrosis 46%
  4 Scopus citations

• Nasally delivered interferon-λ protects mice against infection by SARS-CoV-2 variants including Omicron

  Chong, Z., Karl, C. E., Halfmann, P. J., Kawaoka, Y., Winkler, E. S., Keeler, S. P., Holtzman, M. J., Yu, J. & Diamond, M. S., May 10 2022, In: Cell Reports. 39, 6, 110799.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Interferons 71%
  • Strain 53%
  • Coronavirus Infections 44%
  6 Scopus citations

• Necroptosis triggers spatially restricted neutrophil-mediated vascular damage during lung ischemia reperfusion injury

  Li, W., Terada, Y., Tyurina, Y. Y., Tyurin, V. A., Bery, A. I., Gauthier, J. M., Higashikubo, R., Tong, A. Y., Zhou, D., Nunez-Santana, F., Lecuona, E., Hassan, A., Hashimoto, K., Scozzi, D., Puri, V., Nava, R. G., Krupnick, A. S., Lavine, K. J., Gelman, A. E., Miller, M. J., & 3 othersKagan, V. E., Bharat, A. & Kreisel, D., Mar 8 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 10, e2111537119.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Necroptosis 100%
  • Reperfusion Injury 68%
  • Neutrophils 55%
  • Primary Graft Dysfunction 44%
  • Blood Vessels 41%
  7 Scopus citations

• Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge

  Kafai, N. M., Williamson, L. E., Binshtein, E., Sukupolvi-Petty, S., Gardner, C. L., Liu, J., Mackin, S., Kim, A. S., Kose, N., Carnahan, R. H., Jung, A., Droit, L., Reed, D. S., Handley, S. A., Klimstra, W. B., Crowe, J. E. & Diamond, M. S., Apr 4 2022, In: Journal of Experimental Medicine. 219, 4, e20212532.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Venezuelan Equine Encephalitis Viruses 100%
  • Aerosols 69%
  • Neutralizing Antibodies 63%
  • Monoclonal Antibodies 20%
  • Epitope Mapping 12%
  1 Scopus citations

• Neutral Ligands as Potential ⁶⁴Cu Chelators for Positron Emission Tomography Imaging Applications in Alzheimer's Disease

  Huang, Y., Huynh, T. T., Sun, L., Hu, C. H., Wang, Y. C., Rogers, B. E. & Mirica, L. M., Mar 21 2022, In: Inorganic Chemistry. 61, 11, p. 4778-4787 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Positron 100%
  • ligands 85%
  • Chelating Agent 82%
  • positrons 75%
  • tomography 67%
  3 Scopus citations

• Neutrophil and Macrophage NADPH Oxidase 2 Differentially Control Responses to Inflammation and to Aspergillus fumigatus in Mice

  Idol, R. A., Bhattacharya, S., Huang, G., Song, Z., Huttenlocher, A., Keller, N. P. & Dinauer, M. C., Nov 15 2022, In: Journal of Immunology. 209, 10, p. 1960-1972 13 p.

  Research output: Contribution to journal › Article › peer-review

  • NADPH Oxidase 2 100%
  • Aspergillus fumigatus 77%
  • Neutrophils 49%
  • Macrophages 44%
  • Inflammation 37%
  1 Scopus citations

• Novel Chelating Agents for Zirconium-89-Positron Emission Tomography (PET) Imaging: Synthesis, DFT Calculation, Radiolabeling, and In Vitro and In Vivo Complex Stability

  Kang, C. S., Zhang, S., Wang, H., Liu, Y., Ren, S., Chen, Y., Li, J., Bandara, N., Rogachev, A. Y., Rogers, B. E. & Chong, H. S., Oct 25 2022, In: ACS Omega. 7, 42, p. 37229-37236 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chelation 100%
  • Positron emission tomography 89%
  • Zirconium 81%
  • Discrete Fourier transforms 70%
  • Chelating Agent 62%
  2 Scopus citations

• Novel mechanistic role of Kif26b in adipogenic differentiation of murine multipotent stromal cells

  Yan, M., Cai, L., Duan, X. & Rai, M. F., Feb 12 2022, In: Biochemical and Biophysical Research Communications. 592, p. 125-133 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Adipogenic 100%
  • Stromal Cells 59%
  • Peroxisome Proliferator Activated Receptor Agonist 51%
  • Adipogenesis 47%
  • Rosiglitazone 46%
  1 Scopus citations

• Novel Mouse Model of Murine Cytomegalovirus-Induced Adaptive NK Cells

  Jensen, I. J., Martin, M. D., Tripathy, S. K. & Badovinac, V. P., Jan 1 2022, In: ImmunoHorizons. 6, 1, p. 8-15 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Muromegalovirus 100%
  • Natural Killer Cells 65%
  • Collaborative Cross Mice 33%
  • Immunological Models 14%
  • Infections 12%
  2 Scopus citations

• Occupational characteristics associated with SARS-CoV-2 infection in the UK Biobank during August–November 2020: a cohort study

  Yanik, E. L., Evanoff, B. A., Dale, A. M., Ma, Y. & Walker-Bone, K. E., Dec 2022, In: BMC Public Health. 22, 1, 1884.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Coronavirus Infections 100%
  • Severe Acute Respiratory Syndrome 90%
  • Coronavirus 87%
  • Cohort Studies 47%
  • job title 33%

• Occupational risk factors for work disability following carpal tunnel syndrome: a pooled prospective study

  Harris-Adamson, C., Eisen, E. A., Kapellusch, J., Hegmann, K. T., Thiese, M. S., Dale, A. M., Evanoff, B., Meyers, A. R., Bao, S., Gerr, F., Krause, N. & Rempel, D., Jul 1 2022, In: Occupational and Environmental Medicine. 79, 7, p. 442-451 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Carpal Tunnel Syndrome 100%
  • job change 56%
  • disability 56%
  • Prospective Studies 52%
  • incident 44%
  1 Scopus citations

• One-Year Survival Worse for Lung Retransplants Relative to Primary Lung Transplants

  Randhawa, S. K., Yang, Z., Morkan, D. B., Yan, Chang, S-H., Hachem, R. R., Witt, C., Byers, D. E., Kulkarni, H. S., Guillamet, R. V., Kozower, B. D., Nava, R. G., Meyers, B., Patterson, G. A., Kreisel, D. & Puri, V., Apr 2022, In: Annals of Thoracic Surgery. 113, 4, p. 1265-1273 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Transplants 100%
  • Survival 88%
  • Lung 85%
  • Lung Transplantation 71%
  • Confidence Intervals 14%
  3 Scopus citations

• Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation

  Petroff, J. T., Dietzen, N. M., Santiago-McRae, E., Deng, B., Washington, M. S., Chen, L. J., Trent Moreland, K., Deng, Z., Rau, M., Fitzpatrick, J. A. J., Yuan, P., Joseph, T. T., Hénin, J., Brannigan, G. & Cheng, W. W. L., Dec 2022, In: Nature communications. 13, 1, 7017.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ligand-Gated Ion Channels 100%
  • ligands 73%
  • Phospholipids 65%
  • Phospholipid 61%
  • modulation 48%

• Ornithine decarboxylase supports ILC3 responses in infectious and autoimmune colitis through positive regulation of IL-22 transcription

  Peng, V., Cao, S., Trsan, T., Bando, J. K., Avila-Pacheco, J., Cleveland, J. L., Clish, C., Xavier, R. J. & Colonna, M., Nov 8 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 45, e2214900119.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • interleukin-22 100%
  • Ornithine Decarboxylase 94%
  • Polyamines 87%
  • Colitis 75%
  • Lymphocytes 51%
  1 Scopus citations

• Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1

  Schwarz, M. M., Price, D. A., Ganaie, S. S., Feng, A., Mishra, N., Hoehl, R. M., Fatma, F., Stubbs, S. H., Whelan, S. P. J., Cui, X., Egawa, T., Leung, D. W., Amarasinghe, G. K. & Hartman, A. L., Aug 16 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 33, e2204706119.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bunyaviridae Infections 100%
  • Host Factor 1 Protein 98%
  • Proteins 19%
  • Infections 10%
  • Oropouche orthobunyavirus 8%
  1 Scopus citations

• Overall survival in the SIMPLIFY-1 and SIMPLIFY-2 phase 3 trials of momelotinib in patients with myelofibrosis

  Mesa, R., Harrison, C., Oh, S. T., Gerds, A. T., Gupta, V., Catalano, J., Cervantes, F., Devos, T., Hus, M., Kiladjian, J. J., Lech-Maranda, E., McLornan, D., Vannucchi, A. M., Platzbecker, U., Huang, M., Strouse, B., Klencke, B. & Verstovsek, S., Sep 2022, In: Leukemia. 36, 9, p. 2261-2268 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide 100%
  • Primary Myelofibrosis 64%
  • Survival 28%
  • INCB018424 17%
  • Janus Kinase Inhibitors 15%
  6 Scopus citations

• PDXNet portal: patient-derived Xenograft model, data, workflow and tool discovery

  Koc, S., Lloyd, M. W., Grover, J. W., Xiao, N., Seepo, S., Subramanian, S. L., Ray, M., Frech, C., Digiovanna, J., Webster, P., Neuhauser, S., Srivastava, A., Woo, X. Y., Sanderson, B. J., White, B., Lott, P., Dobrolecki, L. E., Dowst, H., Evrard, Y. A., Wallace, T. A., & 22 othersMoscow, J. A., Doroshow, J. H., Mitsiades, N., Kaochar, S., Pan, C. X., Chen, M. S., Carvajal-Carmona, L., Welm, A. L., Welm, B. E., Lewis, M. T., Govindan, R., Ding, L., Li, S., Herlyn, M., Davies, M. A., Roth, J., Meric-Bernstam, F., Robinson, P. N., Bult, C. J., Davis-Dusenbery, B., Dean, D. A. & Chuang, J. H., Jun 1 2022, In: NAR Cancer. 4, 2, zcac014.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Workflow 100%
  • Heterografts 81%
  • Neoplasms 29%
  • Information Services 27%
  • National Cancer Institute (U.S.) 26%
  1 Scopus citations

• Pediatric and adult dilated cardiomyopathy are distinguished by distinct biomarker profiles

  Gropler, M. R. F., Lipshultz, S. E., Wilkinson, J. D., Towbin, J. A., Colan, S. D., Canter, C. E., Lavine, K. J. & Simpson, K. E., Jul 2022, In: Pediatric research. 92, 1, p. 206-215 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Dilated Cardiomyopathy 100%
  • Biomarkers 59%
  • Pediatrics 59%
  • Blood Proteins 10%
  • Nucleotide Aptamers 8%
  2 Scopus citations

• Peptide-siRNA nanoparticles targeting NF-κB p50 mitigate experimental abdominal aortic aneurysm progression and rupture

  Yan, H., Hu, Y., Akk, A., Wickline, S. A., Pan, H. & Pham, C. T. N., Aug 2022, In: Biomaterials Advances. 139, 213009.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peptides 100%
  • Silencing RNA 98%
  • Nanoparticles 74%
  • Cytokines 42%
  • Intercellular Signaling Peptides and Proteins 38%

• Periarticular calcifications containing giant pseudo-crystals of francolite in skeletal fluorosis from 1,1-difluoroethane “huffing”

  Salles Rosa Neto, N., Englert, D., McAlister, W. H., Mumm, S., Mills, D., Veis, D. J., Burshell, A., Boyde, A. & Whyte, M. P., Jul 2022, In: Bone. 160, 116421.

  Research output: Contribution to journal › Article › peer-review

  • 1,1-difluoroethane 100%
  • Axial osteosclerosis 49%
  • Inhalation 43%
  • fluorapatite 39%
  • Hypophosphatasia 36%

• Personalized neoantigen vaccine NEO-PV-01 with chemotherapy and anti-PD-1 as first-line treatment for non-squamous non-small cell lung cancer

  Awad, M. M., Govindan, R., Balogh, K. N., Spigel, D. R., Garon, E. B., Bushway, M. E., Poran, A., Sheen, J. H., Kohler, V., Esaulova, E., Srouji, J., Ramesh, S., Vyasamneni, R., Karki, B., Sciuto, T. E., Sethi, H., Dong, J. Z., Moles, M. A., Manson, K., Rooney, M. S., & 4 othersKhondker, Z. S., DeMario, M., Gaynor, R. B. & Srinivasan, L., Sep 12 2022, In: Cancer Cell. 40, 9, p. 1010-1026.e11

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Non-Small Cell Lung Carcinoma 100%
  • Vaccines 83%
  • Vaccination 67%
  • Drug Therapy 65%
  • T-Lymphocytes 51%
  5 Scopus citations

• Pevonedistat targets malignant cells in myeloproliferative neoplasms in vitro and in vivo via NFκB pathway inhibition

  Kong, T., Laranjeira, A. B. A., Collins, T. B., De Togni, E. S., Wong, A. J., Fulbright, M. C., Ruzinova, M., Celik, H., Challen, G. A., Fisher, D. A. C. & Oh, S., Jan 25 2022, In: Blood Advances. 6, 2, p. 611-623 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • pevonedistat 100%
  • INCB018424 73%
  • Primary Myelofibrosis 47%
  • N-carboxy-3-phenylpropyl-alanyl-aminoisobutyric acid-tyrosyl-aminobenzoate 41%
  • In Vitro Techniques 24%
  2 Scopus citations

• Phase 1/dose expansion trial of brentuximab vedotin and lenalidomide in relapsed or refractory diffuse large B-cell lymphoma

  Ward, J. P., Berrien-Elliott, M. M., Gomez, F., Luo, J., Becker-Hapak, M., Cashen, A. F., Wagner-Johnston, N. D., Maddocks, K., Mosior, M., Foster, M., Krysiak, K., Schmidt, A., Skidmore, Z. L., Desai, S., Watkins, M. P., Fischer, A., Griffith, M., Griffith, O. L., Fehniger, T. A. & Bartlett, N. L., Mar 31 2022, In: Blood. 139, 13, p. 1999-2010 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Lenalidomide 100%
  • Brentuximab Vedotin 88%
  • Lymphoma, Large B-Cell, Diffuse 62%
  • Refractory 57%
  • Dose 42%
  3 Scopus citations

• Phase I clinical trial evaluating the safety and efficacy of ADP-A2M10 SPEAR T cells in patients with MAGE-A10⁺ advanced non-small cell lung cancer

  Blumenschein, G. R., Devarakonda, S., Johnson, M., Moreno, V., Gainor, J., Edelman, M. J., Heymach, J. V., Govindan, R., Bachier, C., Doger de Spéville, B., Frigault, M. J., Olszanski, A. J., Lam, V. K., Hyland, N., Navenot, J. M., Fayngerts, S., Wolchinsky, Z., Broad, R., Batrakou, D., Pentony, M. M., & 7 othersSanderson, J. P., Gerry, A., Marks, D., Bai, J., Holdich, T., Norry, E. & Fracasso, P. M., Jan 27 2022, In: Journal for ImmunoTherapy of Cancer. 10, 1, e003581.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Melanoma-Specific Antigens 100%
  • antineoplaston A10 88%
  • Clinical Trials, Phase I 86%
  • T-Cell Antigen Receptor 72%
  • Adenosine Diphosphate 71%
  5 Scopus citations

• Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter

  Lim, M., Weller, M., Idbaih, A., Steinbach, J., Finocchiaro, G., Raval, R. R., Ansstas, G., Baehring, J., Taylor, J. W., Honnorat, J., Petrecca, K., De Vos, F., Wick, A., Sumrall, A., Sahebjam, S., Mellinghoff, I. K., Kinoshita, M., Roberts, M., Slepetis, R., Warad, D., & 4 othersLeung, D., Lee, M., Reardon, D. A. & Omuro, A., Nov 2 2022, In: Neuro-oncology. 24, 11, p. 1935-1949 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nivolumab 100%
  • Temozolomide 91%
  • Chemoradiotherapy 78%
  • Glioblastoma 72%
  • Radiotherapy 50%
  28 Scopus citations

• Phase I Study of Accelerated Hypofractionated Proton Therapy and Chemotherapy for Locally Advanced Non-Small Cell Lung Cancer

  Contreras, J., Srivastava, A., Samson, P., DeWees, T., Govindan, R., Baggstrom, M. Q., Morgensztern, D., Roach, M., Badiyan, S. N., Bradley, J., Waqar, S. & Robinson, C., Jul 15 2022, In: International Journal of Radiation Oncology Biology Physics. 113, 4, p. 742-748 7 p.

  Research output: Contribution to journal › Article › peer-review

  • chemotherapy 100%
  • Proton Therapy 93%
  • lungs 75%
  • therapy 65%
  • cancer 64%
  1 Scopus citations

• Physical work exposure matrix for use in the UK Biobank

  Yanik, E. L., Stevens, M. J., Clare Harris, E., Walker-Bone, K. E., Dale, A. M., Ma, Y., Colditz, G. A. & Evanoff, B. A., Mar 2022, In: Occupational Medicine. 72, 2, p. 132-141 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Information Services 100%
  • job title 58%
  • Walking 20%
  • Audiologists 17%
  • Occupational Diseases 14%
  3 Scopus citations

• Pilot Study: PARP1 Imaging in Advanced Prostate Cancer

  Dehdashti, F., Reimers, M. A., Shoghi, K. I., Chen, D. L., Luo, J., Rogers, B., Pachynski, R. K., Sreekumar, S., Weimholt, C. & Zhou, D., Dec 2022, In: Molecular Imaging and Biology. 24, 6, p. 853-861 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Recombinational DNA Repair 100%
  • Prostatic Neoplasms 71%
  • Poly(ADP-ribose) Polymerase Inhibitors 68%
  • Mutation 28%
  • rucaparib 23%

• Point of care tobacco treatment sustains during COVID-19, a global pandemic

  Craig, E. J., Ramsey, A. T., Baker, T. B., James, A. S., Luke, D. A., Malone, S., Chen, J., Pham, G., Smock, N., Goldberg, P., Govindan, R., Bierut, L. J. & Chen, L. S., Jun 2022, In: Cancer Epidemiology. 78, 102005.

  Research output: Contribution to journal › Article › peer-review

  • Point-of-Care Systems 100%
  • Pandemics 94%
  • Tobacco 84%
  • Electronic Health Records 54%
  • Smoking 38%
  5 Scopus citations

• Precision Probiotic Medicine to Improve ICB Immunotherapy

  Di Luccia, B. & Colonna, M., May 1 2022, In: Cancer discovery. 12, 5, p. 1189-1190 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Precision Medicine 100%
  • Probiotics 98%
  • Immunotherapy 81%
  • Lactobacillus delbrueckii 74%
  • Peyer's Patches 60%
  1 Scopus citations

• Prolonged response of recurrent IDH-wild-type glioblastoma to laser interstitial thermal therapy with pembrolizumab

  Hwang, H., Huang, J., Khaddour, K., Butt, O. H., Ansstas, G., Chen, J., Katumba, R. G. N., Kim, A. H., Leuthardt, E. C. & Campian, J. L., Mar 2022, In: CNS oncology. 11, 1, CNS81.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • pembrolizumab 100%
  • Glioblastoma 70%
  • Lasers 57%
  • Hot Temperature 54%
  • Immunotherapy 41%
  2 Scopus citations

• Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

  Ying, B., Whitener, B., VanBlargan, L. A., Hassan, A. O., Shrihari, S., Liang, C. Y., Karl, C. E., Mackin, S., Chen, R. E., Kafai, N. M., Wilks, S. H., Smith, D. J., Carreño, J. M., Singh, G., Krammer, F., Carfi, A., Elbashir, S. M., Edwards, D. K., Thackray, L. B. & Diamond, M., Feb 2 2022, In: Science translational medicine. 14, 630, eabm3302.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Vaccines 58%
  • Messenger RNA 44%
  • K-18 conjugate 42%
  15 Scopus citations

• Proteomic Identification of Potential Target Proteins of Cathepsin W for Its Development as a Drug Target for Influenza

  Günther, S. C., Martínez-Romero, C., Borau, M. S., Pham, C. T. N., García-Sastre, A. & Stertz, S., Aug 2022, In: Microbiology spectrum. 10, 4

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cathepsin W 100%
  • cathepsins 62%
  • influenza 58%
  • proteomics 57%
  • virus 45%

• Proteomic Profile Analysis of Synovial Fluid in Patients With Anterior Cruciate Ligament Tears

  Brophy, R. H., Cai, L., Zhang, Q., Townsend, R. R. & Rai, M. F., Sep 2022, In: American Journal of Sports Medicine.

  Research output: Contribution to journal › Article › peer-review

  • Anterior Cruciate Ligament Injuries 100%
  • Synovial Fluid 90%
  • Proteomics 73%
  • Contusions 46%
  • Wounds and Injuries 34%
  1 Scopus citations

• Racial and socioeconomic differences in acral lentiginous melanoma outcomes: A Surveillance, Epidemiology, and End Results analysis

  Raval, N. S., Hodges, W. T., Ugwu-Dike, P. O., Godoy, F., Ansstas, G., Cornelius, L. A., Musiek, A. C., Asgari, M. M. & Semenov, Y. R., Oct 2022, In: Journal of the American Academy of Dermatology. 87, 4, p. 866-867 2 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Ramucirumab plus atezolizumab in patients with stage IV non-small cell lung cancer previously treated with immune checkpoint inhibitors

  Herzog, B. H., Waqar, S. N., Devarakonda, S., Ward, J. P., Gao, F., Govindan, R. & Morgensztern, D., Nov 2022, In: Lung Cancer. 173, p. 101-106 6 p.

  Research output: Contribution to journal › Article › peer-review

  • ramucirumab 100%
  • atezolizumab 97%
  • Non-Small Cell Lung Carcinoma 55%
  • Progression-Free Survival 15%
  • Survival Rate 13%

• Rates of Guideline-Concordant Surgery and Adjuvant Chemotherapy among Patients with Early-Stage Lung Cancer in the US ALCHEMIST Study (Alliance A151216)

  Kehl, K. L., Zahrieh, D., Yang, P., Hillman, S. L., Tan, A. D., Sands, J. M., Oxnard, G. R., Gillaspie, E. A., Wigle, D., Malik, S., Stinchcombe, T. E., Ramalingam, S. S., Kelly, K., Govindan, R., Mandrekar, S. J., Osarogiagbon, R. U. & Kozono, D., May 2022, In: JAMA oncology. 8, 5, p. 717-728 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Adjuvant Chemotherapy 100%
  • Lung Neoplasms 78%
  • Non-Small Cell Lung Carcinoma 75%
  • Guidelines 63%
  • Lymph Node Excision 55%
  8 Scopus citations

• Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting

  Hauser, B. M., Sangesland, M., St. Denis, K. J., Lam, E. C., Case, J. B., Windsor, I. W., Feldman, J., Caradonna, T. M., Kannegieter, T., Diamond, M. S., Balazs, A. B., Lingwood, D. & Schmidt, A. G., Mar 22 2022, In: Cell Reports. 38, 12, 110561.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome 100%
  • Coronavirus 97%
  • Epitope 79%
  • Epitopes 66%
  • Glycoprotein 28%
  10 Scopus citations

• Reactogenicity of the Messenger RNA SARS–CoV-2 Vaccines Associated With Immunogenicity in Patients With Autoimmune and Inflammatory Disease

  Yang, M. M., Taylor, K. E., Paez, D., Carividi, A., Demissie, E., Pawar, N., El-Qunni, A. A., McMorrow, L. E., Schriefer, R. E., Huang, K., Kinnett, B., Klebert, M., Haile, A., O'Halloran, J. A., Presti, R. M., Kim, W., Ellebedy, A. H., Ciorba, M. A., Paley, M. A., Deepak, P., & 5 othersKim, A. H. J., Katz, P., Matloubian, M., Nakamura, M. & Gensler, L. S., Dec 2022, In: Arthritis Care and Research. 74, 12, p. 1953-1960 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Autoimmune Diseases 100%
  • Vaccines 86%
  • Chronic Disease 85%
  • Messenger RNA 65%
  • Vaccination 39%
  1 Scopus citations