Research Output

Filter
Article
2020

A deletion in the N-terminal polymerizing domain of laminin β2 is a new mouse model of chronic nephrotic syndrome

Funk, S. D., Bayer, R. H., McKee, K. K., Okada, K., Nishimune, H., Yurchenco, P. D. & Miner, J. H., Jan 1 2020, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle

Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification

Yang, L. M., Stout, L., Rauchman, M. & Ornitz, D. M., 2020, (Accepted/In press) In : Developmental Dynamics.

Research output: Contribution to journalArticle

1 Scopus citations

A retrospective study of adult patients with noncirrhotic hyperammonemia

Stergachis, A. B., Mogensen, K. M., Khoury, C. C., Lin, A. P., Peake, R. W. A., Baker, J. J., Barkoudah, E., Sahai, I., Sweetser, D. A., Berry, G. T. & Krier, J. B., 2020, (Accepted/In press) In : Journal of Inherited Metabolic Disease.

Research output: Contribution to journalArticle

A risk calculator to inform the need for a prostate biopsy: a rapid access clinic cohort

Jalali, A., Foley, R. W., Maweni, R. M., Murphy, K., Lundon, D. J., Lynch, T., Power, R., O'Brien, F., O'Malley, K. J., Galvin, D. J., Durkan, G. C., Murphy, T. B. & Watson, R. W., Jul 3 2020, In : BMC Medical Informatics and Decision Making. 20, 1, 1 p.

Research output: Contribution to journalArticle

Open Access

Basement membrane ligands initiate distinct signalling networks to direct cell shape

Randles, M. J., Lausecker, F., Humphries, J. D., Byron, A., Clark, S. J., Miner, J. H., Zent, R., Humphries, M. J. & Lennon, R., Jan 1 2020, (Accepted/In press) In : Matrix Biology.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Cathepsin S and Protease-Activated Receptor-2 Drive Alloimmunity and Immune Regulation in Kidney Allograft Rejection

Lei, Y., Ehle, B., Kumar, S. V., Müller, S., Moll, S., Malone, A. F., Humphreys, B. D., Andrassy, J. & Anders, H. J., Jun 5 2020, In : Frontiers in Cell and Developmental Biology. 8, 398.

Research output: Contribution to journalArticle

Open Access
Open Access

Choroidal thickness in lupus nephritis

Lee, I., Marshall, B., Ranganathan, P., Eisen, S., Rajagopal, R., Kim, A. H. J. & Li, T., Feb 1 2020, In : Lupus. 29, 2, p. 205-209 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Clinical trial recommendations for potential Alport syndrome therapies

Weinstock, B. A., Feldman, D. L., Fornoni, A., Gross, O., Kashtan, C. E., Lagas, S., Lennon, R., Miner, J. H., Rheault, M. N., Simon, J. F., Bonebrake, L., Dunleavy, M., Kumnick, P., Parziale, G., Reed, J., Weinstock, A., Gear, S., Binaso, K., Manuel, R., Simon, J. & 35 others, Appel, G., Blank, M., Tang, W., Thompson, A., Torra, R., Lieberman, K., Licht, C., Dahan, K., Nozu, K., Kai, H., Ricardo, S., Pariser, A., Feldman, D., Cook, H., Chin, M., Goldsberry, A., Meyer, C., Melia, L. A., Komers, R., Markels, M., Mercer, A., Prunotto, M., Morgenstern, B., Hariri, A., Modur, V., Turner, N., Kashtan, C., Rheault, M., Baigent, C., DeSacco, S., Perin, L., Barua, M., Nakanishi, K., Jarad, G. & Miner, J., Jun 2020, In : Kidney International. 97, 6, p. 1109-1116 8 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Cre/loxP approach-mediated downregulation of Pik3c3 inhibits the hypertrophic growth of renal proximal tubule cells

Liu, T., Yuan, J., Dai, C., Xu, J., Li, S., Humphreys, B. D., Kleven, D. T. & Chen, J. K., Jan 1 2020, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Development of a new macrophage-specific TRAP mouse (MacTRAP) and definition of the renal macrophage translational signature

Hofmeister, A., Thomaßen, M. C., Markert, S., Marquardt, A., Preußner, M., Rußwurm, M., Schermuly, R. T., Steinhoff, U., Gröne, H. J., Hoyer, J., Humphreys, B. D. & Grgic, I., Dec 1 2020, In : Scientific reports. 10, 1, 7519.

Research output: Contribution to journalArticle

Open Access

Economic impacts of alternative kidney transplant immunosuppression: A national cohort study

Axelrod, D. A., Caliskan, Y., Schnitzler, M. A., Xiao, H., Dharnidharka, V. R., Segev, D. L., McAdams-DeMarco, M., Brennan, D. C., Randall, H., Alhamad, T., Kasiske, B. L., Hess, G. & Lentine, K. L., Apr 1 2020, In : Clinical Transplantation. 34, 4, e13813.

Research output: Contribution to journalArticle

Effectiveness of a novel, automated telephone intervention on time to hospitalisation in patients with COPD: A randomised controlled trial

Sink, E., Patel, K., Groenendyk, J., Peters, R., Som, A., Kim, E., Xing, M., Blanchard, M. & Ross, W., Apr 1 2020, In : Journal of Telemedicine and Telecare. 26, 3, p. 132-139 8 p.

Research output: Contribution to journalArticle

Efficacy and Safety of Tocilizumab in the Treatment of Acute Active Antibody-mediated Rejection in Kidney Transplant Recipients

Pottebaum, A. A., Venkatachalam, K., Liu, C., Brennan, D. C., Murad, H., Malone, A. F. & Alhamad, T., Jan 1 2020, (Accepted/In press) In : Transplantation Direct. 00988.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Encephalitic alphaviruses exploit caveola-mediated transcytosis at the blood-brain barrier for central nervous system entry

Salimi, H., Cain, M. D., Jiang, X., Roth, R. A., Beatty, W. L., Sun, C., Klimstra, W. B., Hou, J. & Klein, R. S., Jan 1 2020, In : mBio. 11, 1, e02731-19.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Epigenomics and the kidney

Wilson, P. C., Ledru, N. & Humphreys, B. D., May 1 2020, In : Current Opinion in Nephrology and Hypertension. 29, 3, p. 280-285 6 p.

Research output: Contribution to journalArticle

High levels of dd-cfDNA identify patients with TCMR 1A and borderline allograft rejection at elevated risk of graft injury

Stites, E., Kumar, D., Olaitan, O., John Swanson, S., Leca, N., Weir, M., Bromberg, J., Melancon, J., Agha, I., Fattah, H., Alhamad, T., Qazi, Y., Wiseman, A. & Gupta, G., Jan 1 2020, (Accepted/In press) In : American Journal of Transplantation.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

How I treat renal anemia

Fishbane, S. & Coyne, D. W., Aug 13 2020, In : Blood. 136, 7, p. 783-789 7 p.

Research output: Contribution to journalArticle

Imaging effects of hyperosmolality on individual tricellular junctions

Huang, K., Zhou, L., Alanis, K., Hou, J. & Baker, L. A., Jan 1 2020, In : Chemical Science. 11, 5, p. 1307-1315 9 p.

Research output: Contribution to journalArticle

Open Access

Impact of metformin on malignancy in solid organ transplantation

Bartlett, F., January, S., Pottebaum, A., Horwedel, T. & Malone, A. F., Jun 1 2020, In : Clinical Transplantation. 34, 6, e13851.

Research output: Contribution to journalArticle

Interprofessional education and transitions of care: a case-based educational pilot experience

Bland, M., Stevens, A., Nellis, P., Mueggenburg, K., Yau, T. & Chen, J. C., 2020, In : Journal of Interprofessional Care. p. 1-5 5 p.

Research output: Contribution to journalArticle

Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress

Delitsikou, V., Jarad, G., Rajaram, R. D., Ino, F., Rutkowski, J. M., Chen, C. D., Santos, C. X. C., Scherer, P. E., Abraham, C. R., Shah, A. M., Feraille, E., Miner, J. H. & de Seigneux, S., Feb 1 2020, In : FASEB Journal. 34, 2, p. 2087-2104 18 p.

Research output: Contribution to journalArticle

Open Access

Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues

Lin, M. H., Pope, B. D., Sasaki, T., Keeley, D. P., Sherwood, D. R. & Miner, J. H., Jun 1 2020, In : Developmental Dynamics. 249, 6, p. 775-788 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Mutations in LAMB2 Are Associated With Albuminuria and Optic Nerve Hypoplasia With Hypopituitarism

Tahoun, M., Chandler, J. C., Ashton, E., Haston, S., Hannan, A., Kim, J. S., D'arco, F., Bockenhauer, D., Anderson, G., Lin, M. H., Marzouk, S., Saied, M. H., Miner, J. H., Dattani, M. T. & Waters, A. M., Jan 8 2020, In : Journal of Clinical Endocrinology and Metabolism. 105, 3, dgz216.

Research output: Contribution to journalArticle

Open Access

Perceptions and Practices Regarding Frailty in Kidney Transplantation: Results of a National Survey

AST Kidney Pancreas Community of Practice Workgroup, Feb 1 2020, In : Transplantation. 104, 2, p. 349-356 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Peroxidasin-mediated bromine enrichment of basement membranes

He, C., Song, W., Weston, T. A., Tran, C., Kurtz, I., Zuckerman, J. E., Guagliardo, P., Miner, J. H., Ivanov, S. V., Bougoure, J., Hudson, B. G., Colon, S., Voziyan, P. A., Bhave, G., Fong, L. G., Young, S. G. & Jiang, H., Jul 7 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 27, p. 15827-15836 10 p.

Research output: Contribution to journalArticle

Pharmacological inhibition of ataxia-telangiectasia mutated exacerbates acute kidney injury by activating p53 signaling in mice

Uehara, M., Kusaba, T., Ida, T., Nakai, K., Nakata, T., Tomita, A., Watanabe-Uehara, N., Ikeda, K., Kitani, T., Yamashita, N., Kirita, Y., Matoba, S., Humphreys, B. D. & Tamagaki, K., Dec 1 2020, In : Scientific reports. 10, 1, 4441.

Research output: Contribution to journalArticle

Open Access

Pharmacologic inhibition of RGD-binding integrins ameliorates fibrosis and improves function following kidney injury

Basta, J., Robbins, L., Stout, L., Prinsen, M. J., Griggs, D. W. & Rauchman, M., Apr 1 2020, In : Physiological Reports. 8, 7, e14329.

Research output: Contribution to journalArticle

Open Access

Plasma pseudouridine levels reflect body size in children on hemodialysis

O’Brien, F. J., Sirich, T. L., Taussig, A., Fung, E., Ganesan, L. L., Plummer, N. S., Brakeman, P., Sutherland, S. M. & Meyer, T. W., Feb 1 2020, In : Pediatric Nephrology. 35, 2, p. 305-312 8 p.

Research output: Contribution to journalArticle

Poor Outcomes with the Use of Checkpoint Inhibitors in Kidney Transplant Recipients

Venkatachalam, K., Malone, A. F., Heady, B., Santos, R. D. & Alhamad, T., Jan 1 2020, (Accepted/In press) In : Transplantation. p. 1041-1047 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
3 Scopus citations

Single cell sequencing and kidney organoids generated from pluripotent stem cells

Wu, H. & Humphreys, B. D., Apr 1 2020, In : Clinical Journal of the American Society of Nephrology. 15, 4, p. 550-556 7 p.

Research output: Contribution to journalArticle

Open Access

Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker

Kidney Precision Medicine Project (KPMP),5 and Nephrotic Syndrome Study Network (NEPTUNE), Mar 26 2020, In : JCI Insight. 5, 6, e133267.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Sucroferric Oxyhydroxide in Maintenance Hemodialysis: A Retrospective, Comparative Cohort Study

Coyne, D. W., Ficociello, L. H., Parameswaran, V., Rosen, M. M., Mullon, C., Kossmann, R. J. & Sprague, S. M., Jan 1 2020, (Accepted/In press) In : Kidney Medicine.

Research output: Contribution to journalArticle

Open Access

Three-month pancreas graft function significantly influences survival following simultaneous pancreas-kidney transplantation in type 2 diabetes patients

Alhamad, T., Kunjal, R., Wellen, J., Brennan, D. C., Wiseman, A., Ruano, K., Hicks, V., Wang, M., Schnitzler, M. A., Chang, S. H. & Lentine, K. L., Mar 1 2020, In : American Journal of Transplantation. 20, 3, p. 788-796 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

A conditionally immortalized Gli1-positive kidney mesenchymal cell line models myofibroblast transition

Ó Hainmhire, E., Wu, H., Muto, Y., Donnelly, E. L., Machado, F. G., Fan, L. X., Chang-Panesso, M. & Humphreys, B. D., Jan 2019, In : American Journal of Physiology - Renal Physiology. 316, 1, p. F63-F75

Research output: Contribution to journalArticle

3 Scopus citations
48 Scopus citations

A Multimodality Approach to Assessing Factor I Genetic Variants in Atypical Hemolytic Uremic Syndrome

Java, A., Pozzi, N., Love-Gregory, L. D., Heusel, J. W., Sung, Y. J., Hu, Z., Bertram, P., Liszewski, M. K., Cline, L. M., Ren, Z. & Atkinson, J. P., Jul 2019, In : Kidney International Reports. 4, 7, p. 1007-1017 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A Patient Decision Support Tool for Hepatitis C Virus and CKD Treatment

George, N., Liapakis, A. M., Korenblat, K. M., Li, T., Roth, D., Yee, J., Fowler, K. J., Howard, L., Liu, J. & Politi, M. C., Jul 1 2019, In : Kidney Medicine. 1, 4, p. 200-206 7 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
1 Scopus citations

A single-nucleus RNA-sequencing pipeline to decipher the molecular anatomy and pathophysiology of human kidneys

Lake, B. B., Chen, S., Hoshi, M., Plongthongkum, N., Salamon, D., Knoten, A., Vijayan, A., Venkatesh, R., Kim, E. H., Gao, D., Gaut, J., Zhang, K. & Jain, S., Dec 1 2019, In : Nature communications. 10, 1, 2832.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Cannabis Dependence or Abuse in Kidney Transplantation: Implications for Posttransplant Outcomes

Alhamad, T., Koraishy, F. M., Lam, N. N., Katari, S., Naik, A. S., Schnitzler, M. A., Xiao, H., Axelrod, D. A., Dharnidharka, V. R., Randall, H., Ouseph, R., Segev, D. L., Brennan, D. C., Devraj, R., Kasiske, B. L. & Lentine, K. L., Nov 1 2019, In : Transplantation. 103, 11, p. 2373-2382 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Changes in serum albumin and other nutritional markers when using sucroferric oxyhydroxide as phosphate binder among hemodialysis patients: A historical cohort study

Kalantar-Zadeh, K., Ficociello, L. H., Parameswaran, V., Athienites, N. V., Mullon, C., Kossmann, R. J. & Coyne, D. W., Oct 29 2019, In : BMC Nephrology. 20, 1, 396.

Research output: Contribution to journalArticle

Open Access

Claudin-4 reconstituted in unilamellar vesicles is sufficient to form tight interfaces that partition membrane proteins

Belardi, B., Son, S., Vahey, M. D., Wang, J., Hou, J. & Fletcher, D. A., Feb 1 2019, In : Journal of cell science. 132, 4, jcs221556.

Research output: Contribution to journalArticle

7 Scopus citations

Differential expression of parietal epithelial cell and podocyte extracellular matrix proteins in focal segmental glomerulosclerosis and diabetic nephropathy

Chan, G. C., Eng, D. G., Miner, J. H., Alpers, C. E., Hudkins, K., Chang, A., Pippin, J. W. & Shankland, S. J., 2019, In : American Journal of Physiology - Renal Physiology. 317, 6, p. F1680-F1694

Research output: Contribution to journalArticle

4 Scopus citations

Dual lineage tracing shows that glomerular parietal epithelial cells can transdifferentiate toward the adult podocyte fate

Kaverina, N. V., Eng, D. G., Freedman, B. S., Kutz, J. N., Chozinski, T. J., Vaughan, J. C., Miner, J. H., Pippin, J. W. & Shankland, S. J., Sep 2019, In : Kidney International. 96, 3, p. 597-611 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

Dynamic host immune response in virus-associated cancers

Cao, S., Wylie, K. M., Wyczalkowski, M. A., Karpova, A., Ley, J., Sun, S., Mashl, R. J., Liang, W. W., Wang, X., Johnson, K., DiPersio, J. F., Gay, H., Ratner, L., Chen, F., Adkins, D. R. & Ding, L., Dec 1 2019, In : Communications Biology. 2, 1, 109.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
1 Scopus citations

Estimates of the 2016 global burden of kidney disease attributable to ambient fine particulate matter air pollution

Bowe, B., Xie, Y., Li, T., Yan, Y., Xian, H. & Al-Aly, Z., May 1 2019, In : BMJ Open. 9, 5, e022450.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations