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  • 2018

    The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer's disease

    Dominantly Inherited Alzheimer Network (DIAN), Nov 26 2018, In: Acta Neuropathologica Communications. 6, 1, p. 130 1 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    50 Scopus citations

  • Three VCP Mutations in Patients with Frontotemporal Dementia

    Wong, T. H., Pottier, C., Hondius, D. C., Meeter, L. H. H., Van Rooij, J. G. J., Melhem, S., Van Minkelen, R., Van Duijn, C. M., Rozemuller, A. J. M., Seelaar, H., Rademakers, R. & Van Swieten, J. C., 2018, In: Journal of Alzheimer's Disease. 65, 4, p. 1139-1146 8 p.

    Research output: Contribution to journal › Article › peer-review

    20 Scopus citations

  • Utility of perfusion PET measures to assess neuronal injury in Alzheimer's disease

    Dominantly Inherited Alzheimer Network, Jan 1 2018, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 669-677 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    20 Scopus citations

  • White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease

    Caballero, M. Á. A., Suárez-Calvet, M., Duering, M., Franzmeier, N., Benzinger, T., Fagan, A. M., Bateman, R. J., Jack, C. R., Levin, J., Dichgans, M., Jucker, M., Karch, C., Masters, C. L., Morris, J. C., Weiner, M., Rossor, M., Fox, N. C., Lee, J. H., Salloway, S. & Danek, A. & 6 others, Goate, A., Yakushev, I., Hassenstab, J., Schofield, P. R., Haass, C. & Ewers, M., Oct 1 2018, In: Brain. 141, 10, p. 3065-3080 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    117 Scopus citations

  • Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease

    The Alzheimer's Disease Sequencing Project, Apr 1 2018, In: Annals of Clinical and Translational Neurology. 5, 4, p. 406-417 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    36 Scopus citations
  • 2017

    A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

    Huang, K. L., Marcora, E., Pimenova, A. A., Di Narzo, A. F., Kapoor, M., Jin, S. C., Harari, O., Bertelsen, S., Fairfax, B. P., Czajkowski, J., Chouraki, V., Grenier-Boley, B., Bellenguez, C., Deming, Y., McKenzie, A., Raj, T., Renton, A. E., Budde, J., Smith, A. & Fitzpatrick, A. & 27 others, Bis, J. C., DeStefano, A., Adams, H. H. H., Ikram, M. A., Van Der Lee, S., Del-Aguila, J. L., Fernandez, M. V., Ibañez, L., Sims, R., Escott-Price, V., Mayeux, R., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lambert, J. C., Van Duijn, C., Launer, L., Seshadri, S., Williams, J., Amouyel, P., Schellenberg, G. D., Zhang, B., Borecki, I., Kauwe, J. S. K., Cruchaga, C., Hao, K. & Goate, A. M., Aug 1 2017, In: Nature neuroscience. 20, 8, p. 1052-1061 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    277 Scopus citations

  • A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains

    Haddick, P. C. G., Larson, J. L., Rathore, N., Bhangale, T. R., Phung, Q. T., Srinivasan, K., Hansen, D. V., Lill, J. R., Pericak-Vance, M. A., Haines, J., Farrer, L. A., Kauwe, J. S., Schellenberg, G. D., Cruchaga, C., Goate, A. M., Behrens, T. W., Watts, R. J., Graham, R. R., Kaminker, J. S. & Van Der Brug, M., 2017, In: Journal of Alzheimer's Disease. 56, 3, p. 1037-1054 18 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    42 Scopus citations

  • Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation

    Song, W., Hooli, B., Mullin, K., Jin, S. C., Cella, M., Ulland, T. K., Wang, Y., Tanzi, R. E. & Colonna, M., Apr 1 2017, In: Alzheimer's and Dementia. 13, 4, p. 381-387 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    191 Scopus citations

  • Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease

    NIA-LOAD family study group & NCRAD, Nov 2017, In: PLoS genetics. 13, 11, e1007045.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    28 Scopus citations

  • An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells

    TCW, J., Wang, M., Pimenova, A. A., Bowles, K. R., Hartley, B. J., Lacin, E., Machlovi, S. I., Abdelaal, R., Karch, C. M., Phatnani, H., Slesinger, P. A., Zhang, B., Goate, A. M. & Brennand, K. J., Aug 8 2017, In: Stem Cell Reports. 9, 2, p. 600-614 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    261 Scopus citations

  • ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

    Alzheimer’s Disease Neuroimaging Initiative, Sep 28 2017, In: Nature. 549, 7673, p. 523-527 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    828 Scopus citations

  • Caspase-8, association with Alzheimer’s Disease and functional analysis of rare variants

    Rehker, J., Rodhe, J., Nesbitt, R. R., Boyle, E. A., Martin, B. K., Lord, J., Karaca, I., Naj, A., Jessen, F., Helisalmi, S., Soininen, H., Hiltunen, M., Ramirez, A., Scherer, M., Farrer, L. A., Haines, J. L., Pericak-Vance, M. A., Raskind, W. H., Cruchaga, C. & Schellenberg, G. D. & 2 others, Joseph, B. & Brkanac, Z., Oct 2017, In: PloS one. 12, 10, e0185777.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    33 Scopus citations

  • Clinical and neuropathological features of ALS/FTD with TIA1 mutations

    Hirsch-Reinshagen, V., Pottier, C., Nicholson, A. M., Baker, M., Hsiung, G. Y. R., Krieger, C., Sengdy, P., Boylan, K. B., Dickson, D. W., Mesulam, M., Weintraub, S., Bigio, E., Zinman, L., Keith, J., Rogaeva, E., Zivkovic, S. A., Lacomis, D., Taylor, J. P., Rademakers, R. & Mackenzie, I. R. A., Dec 7 2017, In: Acta Neuropathologica Communications. 5, 1, p. 96 1 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    37 Scopus citations

  • Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands

    Jin, S. C., Homsy, J., Zaidi, S., Lu, Q., Morton, S., Depalma, S. R., Zeng, X., Qi, H., Chang, W., Sierant, M. C., Hung, W. C., Haider, S., Zhang, J., Knight, J., Bjornson, R. D., Castaldi, C., Tikhonoa, I. R., Bilguvar, K., Mane, S. M. & Sanders, S. J. & 25 others, Mital, S., Russell, M. W., Gaynor, J. W., Deanfield, J., Giardini, A., Porter, G. A., Srivastava, D., Lo, C. W., Shen, Y., Watkins, W. S., Yandell, M., Yost, H. J., Tristani-Firouzi, M., Newburger, J. W., Roberts, A. E., Kim, R., Zhao, H., Kaltman, J. R., Goldmuntz, E., Chung, W. K., Seidman, J. G., Gelb, B. D., Seidman, C. E., Lifton, R. P. & Brueckner, M., Nov 1 2017, In: Nature Genetics. 49, 11, p. 1593-1601 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    573 Scopus citations

  • CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN

    Fardo, D. W., Katsumata, Y., Kauwe, J. S. K., Deming, Y., Harari, O., Cruchaga, C. & Nelson, P. T., Apr 1 2017, In: Experimental Gerontology. 90, p. 83-89 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases

    The IFGC and IPDGC members, Feb 1 2017, In: Journal of Neurology, Neurosurgery and Psychiatry. 88, 2, p. 152-164 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    90 Scopus citations

  • Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

    Desikan, R. S., Fan, C. C., Wang, Y., Schork, A. J., Cabral, H. J., Cupples, L. A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J. & Miller, B. L. & 14 others, Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A. & Dale, A. M., Mar 2017, In: PLoS medicine. 14, 3, e1002258.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    283 Scopus citations

  • Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke

    Phuah, C. L., Dave, T., Malik, R., Raffeld, M. R., Ayres, A. M., Goldstein, J. N., Viswanathan, A., Greenberg, S. M., Jagiella, J. M., Hansen, B. M., Norrving, B., Jimenez-Conde, J., Roquer, J., Pichler, A., Enzinger, C., Montaner, J., Fernandez-Cadenas, I., Lindgren, A., Slowik, A. & Schmidt, R. & 11 others, Biffi, A., Rost, N., Langefeld, C. D., Markus, H. S., Mitchell, B. D., Worrall, B. B., Kittner, S. J., Woo, D., Dichgans, M., Rosand, J. & Anderson, C. D., Oct 1 2017, In: Brain. 140, 10, p. 2663-2672 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    13 Scopus citations

  • Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism

    ADGC, Alzheimer’s Disease Neuroimaging Initiative, Jun 1 2017, In: Acta Neuropathologica. 133, 6, p. 955-966 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    44 Scopus citations

  • Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

    Alzheimer’s Disease Neuroimaging Initiative (ADNI) & The Alzheimer Disease Genetic Consortium (ADGC), May 1 2017, In: Acta Neuropathologica. 133, 5, p. 839-856 18 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    164 Scopus citations

  • Genome-Wide Gene-Potassium Interaction Analyses on Blood Pressure: The GenSalt Study (Genetic Epidemiology Network of Salt Sensitivity)

    Li, C., He, J., Chen, J., Zhao, J., Gu, D., Hixson, J. E., Rao, D. C., Jaquish, C. E., Rice, T. K., Sung, Y. J. & Kelly, T. N., Dec 1 2017, In: Circulation: Cardiovascular Genetics. 10, 6, e001811.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations

  • Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

    Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L. & Mahajan, A. & 297 others, Renström, F., Wu, J., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg, J., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Harder, M. N., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, J. M., Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L. P., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pe'russe, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stanča'kova, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., Van Der Laan, S. W., Van Der Most, P. J., Van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Zhao, J. H., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., De Borst, G. J., De Craen, A. J. M., De Geus, E. J. C., Dedoussis, G., Delgado, G. E., Den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Hottenga, J. J., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J. O., Jarvelin, M. R., Jhun, M. A., Jorgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaloy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, A., Lobbens, S., Loh, M., Lorentzon, M., Luben, R., Lubke, G., Ludolph-Donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P., Martin, N. G., McKenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. W., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M. C., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Ida Chen, Y. D., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., De Faire, U., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H. J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Jukema, J. W., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Le Marchand, L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, O., Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sorensen, T. I. A., Strauch, K., Tiemeier, H., Tremoli, E., Van Der Harst, P., Vestergaard, H., Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., Van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J., Loos, R. J. F., Kilpeläinen, T. O., Liu, C. T., Borecki, I. B., North, K. E. & Cupples, L. A., 2017, In: Nature communications. 8, 14977.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    144 Scopus citations

  • Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience

    for the Alzheimer's Disease Neuroimaging Initative, Nov 29 2017, In: Genome medicine. 9, 1, 100.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    59 Scopus citations

  • Multiancestry Study of Gene-Lifestyle Interactions for Cardiovascular Traits in 610 475 Individuals from 124 Cohorts: Design and Rationale

    Rao, D. C., Sung, Y. J., Winkler, T. W., Schwander, K., Borecki, I., Adrienne Cupples, L., James Gauderman, W., Rice, K., Munroe, P. B. & Psaty, B. M., Jun 1 2017, In: Circulation: Cardiovascular Genetics. 10, 3, e001649.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    46 Scopus citations

  • Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels

    Ibanez, L., Dube, U., Saef, B., Budde, J., Black, K., Medvedeva, A., Del-Aguila, J. L., Davis, A. A., Perlmutter, J. S., Harari, O., Benitez, B. A. & Cruchaga, C., Nov 15 2017, In: BMC Neurology. 17, 1, 198.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    55 Scopus citations

  • Polygenic risk scores in familial Alzheimer disease

    Tosto, G., Bird, T. D., Tsuang, D., Bennett, D. A., Boeve, B. F., Cruchaga, C., Faber, K., Foroud, T. M., Farlow, M., Goate, A. M., Bertlesen, S., Graff-Radford, N. R., Medrano, M., Lantigua, R., Manly, J., Ottman, R., Rosenberg, R., Schaid, D. J., Schupf, N. & Stern, Y. & 2 others, Sweet, R. A. & Mayeux, R., Mar 21 2017, In: Neurology. 88, 12, p. 1180-1186 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    48 Scopus citations

  • Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry

    Nandakumar, P., Lee, D., Richard, M. A., Tekola-Ayele, F., Tayo, B. O., Ware, E., Sung, Y. J., Salako, B., Ogunniyi, A., Gu, C. C., Grove, M. L., Fornage, M., Kardia, S., Rotimi, C., Cooper, R. S., Morrison, A. C., Ehret, G. & Chakravarti, A., Jul 1 2017, In: Journal of Hypertension. 35, 7, p. 1381-1389 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Scopus citations

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R. & Olaso, R. & 426 others, Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Longstreth, W. T., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J. C., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. 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A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Goate, A. M., Pericak-Vance, M. A., Holmans, P. A., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., Sep 1 2017, In: Nature Genetics. 49, 9, p. 1373-1384 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    678 Scopus citations

  • Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening

    Wang, C., Ward, M. E., Chen, R., Liu, K., Tracy, T. E., Chen, X., Xie, M., Sohn, P. D., Ludwig, C., Meyer-Franke, A., Karch, C. M., Ding, S. & Gan, L., Oct 10 2017, In: Stem Cell Reports. 9, 4, p. 1221-1233 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    203 Scopus citations

  • Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia

    International FTD-Genomics Consortium (IFGC), May 1 2017, In: Acta Neuropathologica. 133, 5, p. 825-837 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    79 Scopus citations

  • Study of genetic variants in the BDNF, COMT, DAT1 and SERT genes in Colombian children with attention deficit disorder

    Translated title of the contribution: Study of genetic variants in the BDNF, COMT, DAT1 and SERT genes in Colombian children with attention deficit disorderOrtega-Rojas, J., Arboleda-Bustos, C. E., Morales, L., Benítez, B. A., Beltrán, D., Izquierdo, Á., Arboleda, H. & Vásquez, R., Oct 2017, In: Revista Colombiana de Psiquiatria. 46, 4, p. 222-228 7 p.

    Research output: Contribution to journal › Article › peer-review

    5 Scopus citations

  • Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS

    Taskesen, E., Mishra, A., van der Sluis, S., Ferrari, R., Veldink, J. H., van Es, M. A., Smit, A. B., Posthuma, D., Pijnenburg, Y., Hernandez, D. G., Nalls, M. A., Rohrer, J. D., Ramasamy, A., Kwok, J. B. J., Dobson-Stone, C., Schofield, P. R., Halliday, G. M., Hodges, J. R., Piguet, O. & Bartley, L. & 142 others, Thompson, E., Haan, E., Hernández, I., Ruiz, A., Boada, M., Borroni, B., Padovani, A., Cruchaga, C., Cairns, N. J., Benussi, L., Binetti, G., Ghidoni, R., Forloni, G., Albani, D., Galimberti, D., Fenoglio, C., Serpente, M., Scarpini, E., Clarimón, J., Lleó, A., Blesa, R., Waldö, M. L., Nilsson, K., Nilsson, C., Mackenzie, I. R. A., Hsiung, G. Y. R., Mann, D. M. A., Grafman, J., Morris, C. M., Attems, J., Griffiths, T. D., McKeith, I. G., Thomas, A. J., Pietrini, P., Huey, E. D., Wassermann, E. M., Baborie, A., Jaros, E., Tierney, M. C., Pastor, P., Razquin, C., Ortega-Cubero, S., Alonso, E., Perneczky, R., Diehl-Schmid, J., Alexopoulos, P., Kurz, A., Rainero, I., Rubino, E., Pinessi, L., Rogaeva, E., St George-Hyslop, P., Rossi, G., Tagliavini, F., Giaccone, G., Rowe, J. B., Schlachetzki, J. C. M., Uphill, J., Collinge, J., Mead, S., Danek, A., Van Deerlin, V. M., Grossman, M., Trojanowski, J. Q., van der Zee, J., Van Broeckhoven, C., Cappa, S. F., Leber, I., Hannequin, D., Golfier, V., Vercelletto, M., Brice, A., Nacmias, B., Sorbi, S., Bagnoli, S., Piaceri, I., Nielsen, J. E., Hjermind, L. E., Riemenschneider, M., Mayhaus, M., Ibach, B., Gasparoni, G., Pichler, S., Gu, W., Rossor, M. N., Fox, N. C., Warren, J. D., Spillantini, M. G., Morris, H. R., Rizzu, P., Heutink, P., Snowden, J. S., Rollinson, S., Richardson, A., Gerhard, A., Bruni, A. C., Maletta, R., Frangipane, F., Cupidi, C., Bernardi, L., Anfossi, M., Gallo, M., Conidi, M. E., Smirne, N., Rademakers, R., Baker, M., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Knopman, D., Josephs, K. A., Boeve, B. F., Parisi, J. E., Seeley, W. W., Miller, B. L., Karydas, A. M., Rosen, H., van Swieten, J. C., Dopper, E. G. P., Seelaar, H., Scheltens, P., Logroscino, G., Capozzo, R., Novelli, V., Puca, A. A., Franceschi, M., Postiglione, A., Milan, G., Sorrentino, P., Kristiansen, M., Chiang, H. H., Graff, C., Pasquier, F., Rollin, A., Deramecourt, V., Lebouvier, T., Kapogiannis, D., Ferrucci, L., Pickering-Brown, S., Singleton, A. B., Hardy, J. & Momeni, P., Dec 1 2017, In: Scientific reports. 7, 1, 8899.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    33 Scopus citations

  • TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

    Mackenzie, I. R., Nicholson, A. M., Sarkar, M., Messing, J., Purice, M. D., Pottier, C., Annu, K., Baker, M., Perkerson, R. B., Kurti, A., Matchett, B. J., Mittag, T., Temirov, J., Hsiung, G. Y. R., Krieger, C., Murray, M. E., Kato, M., Fryer, J. D., Petrucelli, L. & Zinman, L. & 22 others, Weintraub, S., Mesulam, M., Keith, J., Zivkovic, S. A., Hirsch-Reinshagen, V., Roos, R. P., Züchner, S., Graff-Radford, N. R., Petersen, R. C., Caselli, R. J., Wszolek, Z. K., Finger, E., Lippa, C., Lacomis, D., Stewart, H., Dickson, D. W., Kim, H. J., Rogaeva, E., Bigio, E., Boylan, K. B., Taylor, J. P. & Rademakers, R., Aug 16 2017, In: Neuron. 95, 4, p. 808-816.e9

    Research output: Contribution to journal › Article › peer-review

    Open Access
    466 Scopus citations

  • TMEM230 in Parkinson's disease

    Ibanez, L., Dube, U., Budde, J., Black, K., Medvedeva, A., Davis, A. A., Perlmutter, J. S., Benitez, B. A. & Cruchaga, C., Aug 2017, In: Neurobiology of Aging. 56, p. 212.e1-212.e3

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • Transethnic genome-wide scan identifies novel Alzheimer's disease loci

    Alzheimer's Disease Genetics Consortium, Jul 1 2017, In: Alzheimer's and Dementia. 13, 7, p. 727-738 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    134 Scopus citations
  • 2016

    ABCA7 p.G215S as potential protective factor for Alzheimer's disease

    Sassi, C., Nalls, M. A., Ridge, P. G., Gibbs, J. R., Ding, J., Lupton, M. K., Troakes, C., Lunnon, K., Al-Sarraj, S., Brown, K. S., Medway, C., Clement, N., Lord, J., Turton, J., Bras, J., Almeida, M. R., Passmore, P., Craig, D., Johnston, J. & McGuinness, B. & 29 others, Todd, S., Heun, R., Kölsch, H., Kehoe, P. G., Vardy, E. R. L. C., Hooper, N. M., Mann, D. M., Pickering-Brown, S., Brown, K., Lowe, J., Morgan, K., Smith, A. D., Wilcock, G., Warden, D., Holmes, C., Holstege, H., Louwersheimer, E., van der Flier, W. M., Scheltens, P., Van Swieten, J. C., Santana, I., Oliveira, C., Powell, J. F., Kauwe, J. S., Cruchaga, C., Goate, A. M., Singleton, A. B., Guerreiro, R. & Hardy, J., Oct 1 2016, In: Neurobiology of Aging. 46, p. 235.e1-235.e9

    Research output: Contribution to journal › Article › peer-review

    Open Access
    47 Scopus citations

  • A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

    CHD Exome+ Consortium, CARDIOGRAM Exome Consortium & GERAD-EC Consortium, Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE), Jun 1 2016, In: Science translational medicine. 8, 341, 341ra76.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    96 Scopus citations

  • Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

    Alzheimer's Disease Genetics Consortium (ADGC), Feb 2016, In: PloS one. 11, 2, e0148717.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    83 Scopus citations

  • An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group

    Sung, Y. J., Winkler, T. W., Manning, A. K., Aschard, H., Gudnason, V., Harris, T. B., Smith, A. V., Boerwinkle, E., Brown, M. R., Morrison, A. C., Fornage, M., Lin, L. A., Richard, M., Bartz, T. M., Psaty, B. M., Hayward, C., Polasek, O., Marten, J., Rudan, I. & Feitosa, M. F. & 38 others, Kraja, A. T., Province, M. A., Deng, X., Fisher, V. A., Zhou, Y., Bielak, L. F., Smith, J., Huffman, J. E., Padmanabhan, S., Smith, B. H., Ding, J., Liu, Y., Lohman, K., Bouchard, C., Rankinen, T., Rice, T. K., Arnett, D., Schwander, K., Guo, X., Palmas, W., Rotter, J. I., Alfred, T., Bottinger, E. P., Loos, R. J. F., Amin, N., Franco, O. H., van Duijn, C. M., Vojinovic, D., Chasman, D. I., Ridker, P. M., Rose, L. M., Kardia, S., Zhu, X., Rice, K., Borecki, I. B., Rao, D. C., Gauderman, W. J. & Cupples, L. A., Jul 1 2016, In: Genetic Epidemiology. 40, 5, p. 404-415 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    18 Scopus citations

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L. & Ikram, M. A. & 332 others, Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. F., Hampel, H., Kamboh, M. I., De Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carasquillo, M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., Van Duijn, C. M., Schellenberg, G. D., Farrer, L. A., Adams, P. M., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barmada, M. M., Barnes, L. L., Beach, T. G., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., DeCarli, C., DeKosky, S. T., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Faber, K. M., Fairchild, T. J., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C. K., Yu, C. E., Yu, L., Thomas, C., Gerrish, A., Chapman, J., Stretton, A., Morgan, A., Oldham, H., Owen, M. J., Kehoe, P. G., Medway, C., Brown, K., Lord, J., Turton, J., Hooper, N. M., Vardy, E., Warren, J. D., Schott, J. M., Uphill, J., Hollingworth, P., Ryan, N., Rossor, M., Collinge, J., Ben-Shlomo, Y., Makrina, D., Gkatzima, O., Lupton, M., Koutroumani, M., Avramidou, D., Germanou, A., Jessen, F., Riedel-Heller, S., Dichgans, M., Heun, R., Kölsch, H., Schürmann, B., Herold, C., Lacour, A., Drichel, D., Hoffmann, P., Kornhuber, J., Gu, W., Feulner, T., Mayhaus, M., Pichler, S., Riemenschneider, M., van den Bussche, H., Lawlor, B., Lynch, A., Mann, D., Smith, A. D., Warden, D., Wilcock, G., Heuser, I., Wiltfang, J., Frölich, L., Hüll, M., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Russo, G., Jöckel, K. H., Moebus, S., Klopp, N., Wichmann, H. E., Ma, L., Bisceglio, G., Fisher, E., Warner, N., Pickering-Brown, S., Craig, D., Johnston, J. A., McGuinness, B., Todd, S., Rubinsztein, D. C., Lovestone, S., Bayer, A., Gallacher, J., Proitsi, P. & Ortega-Cubero, S., Jan 1 2016, In: Molecular Psychiatry. 21, 1, p. 108-117 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    193 Scopus citations

  • APOE polymorphisms influence longitudinal lipid trends preceding intracerebral hemorrhage

    Phuah, C. L., Raffeld, M. R., Ayres, A. M., Edip Gurol, M., Viswanathan, A., Greenberg, S. M., Biffi, A., Rosand, J. & Anderson, C. D., Aug 1 2016, In: Neurology: Genetics. 2, 4, e81.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • A polygenic burden of rare variants across extracellular matrix genes among individuals with adolescent idiopathic scoliosis

    Haller, G., Alvarado, D., Mccall, K., Yang, P., Cruchaga, C., Harms, M., Goate, A., Willing, M., Morcuende, J. A., Baschal, E., Miller, N. H., Wise, C., Dobbs, M. B. & Gurnett, C. A., Jan 1 2016, In: Human molecular genetics. 25, 1, p. 202-209 8 p.

    Research output: Contribution to journal › Article › peer-review

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    60 Scopus citations

  • A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin

    Deming, Y., Xia, J., Cai, Y., Lord, J., Holmans, P., Bertelsen, S., Holtzman, D., Morris, J. C., Bales, K., Pickering, E. H., Kauwe, J., Goate, A. & Cruchaga, C., Jan 1 2016, In: Neurobiology of Aging. 37, p. 208.e1-208.e9

    Research output: Contribution to journal › Article › peer-review

    Open Access
    48 Scopus citations

  • A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

    Ried, J. S., Jeff, J. M., Chu, A. Y., Bragg-Gresham, J. L., Van Dongen, J., Huffman, J. E., Ahluwalia, T. S., Cadby, G., Eklund, N., Eriksson, J., Esko, T., Feitosa, M. F., Goel, A., Gorski, M., Hayward, C., Heard-Costa, N. L., Jackson, A. U., Jokinen, E., Kanoni, S. & Kristiansson, K. & 256 others, Kutalik, Z., Lahti, J., Luan, J., Mägi, R., Mahajan, A., Mangino, M., Medina-Gomez, C., Monda, K. L., Nolte, I. M., Pérusse, L., Prokopenko, I., Qi, L., Rose, L. M., Salvi, E., Smith, M. T., Snieder, H., Standáková, A., Ju Sung, Y., Tachmazidou, I., Teumer, A., Thorleifsson, G., Van Der Harst, P., Walker, R. W., Wang, S. R., Wild, S. H., Willems, S. M., Wong, A., Zhang, W., Albrecht, E., Couto Alves, A., Bakker, S. J. L., Barlassina, C., Bartz, T. M., Beilby, J., Bellis, C., Bergman, R. N., Bergmann, S., Blangero, J., Blüher, M., Boerwinkle, E., Bonnycastle, L. L., Bornstein, S. R., Bruinenberg, M., Campbell, H., Chen, Y. D. I., Chiang, C. W. K., Chines, P. S., Collins, F. S., Cucca, F., Cupples, L. A., D'avila, F., De Geus, E. J. C., Dedoussis, G., Dimitriou, M., Döring, A., Eriksson, J. G., Farmaki, A. E., Farrall, M., Ferreira, T., Fischer, K., Forouhi, N. G., Friedrich, N., Gjesing, A. P., Glorioso, N., Graff, M., Grallert, H., Grarup, N., Gräßler, J., Grewal, J., Hamsten, A., Harder, M. N., Hartman, C. A., Hassinen, M., Hastie, N., Hattersley, A. T., Havulinna, A. S., Heliövaara, M., Hillege, H., Hofman, A., Holmen, O., Homuth, G., Hottenga, J. J., Hui, J., Husemoen, L. L., Hysi, P. G., Isaacs, A., Ittermann, T., Jalilzadeh, S., James, A. L., Jørgensen, T., Jousilahti, P., Jula, A., Marie Justesen, J., Justice, A. E., Kähönen, M., Karaleftheri, M., Tee Khaw, K., Keinanen-Kiukaanniemi, S. M., Kinnunen, L., Knekt, P. B., Koistinen, H. A., Kolcic, I., Kooner, I. K., Koskinen, S., Kovacs, P., Kyriakou, T., Laitinen, T., Langenberg, C., Lewin, A. M., Lichtner, P., Lindgren, C. M., Lindström, J., Linneberg, A., Lorbeer, R., Lorentzon, M., Luben, R., Lyssenko, V., Männistö, S., Manunta, P., Leach, I. M., Mcardle, W. L., Mcknight, B., Mohlke, K. L., Mihailov, E., Milani, L., Mills, R., Montasser, M. E., Morris, A. P., Müller, G., Musk, A. W., Narisu, N., Ong, K. K., Oostra, B. A., Osmond, C., Palotie, A., Pankow, J. S., Paternoster, L., Penninx, B. W., Pichler, I., Pilia, M. G., Polašek, O., Pramstaller, P. P., Raitakari, O. T., Rankinen, T., Rao, D. C., Rayner, N. W., Ribel-Madsen, R., Rice, T. K., Richards, M., Ridker, P. M., Rivadeneira, F., Ryan, K. A., Sanna, S., Sarzynski, M. A., Scholtens, S., Scott, R. A., Sebert, S., Southam, L., Sparsø, T. H., Steinthorsdottir, V., Stirrups, K., Stolk, R. P., Strauch, K., Stringham, H. M., Swertz, M. A., Swift, A. J., Tönjes, A., Tsafantakis, E., Van Der Most, P. J., Van Vliet-Ostaptchouk, J. V., Vandenput, L., Vartiainen, E., Venturini, C., Verweij, N., Viikari, J. S., Vitart, V., Vohl, M. C., Vonk, J. M., Waeber, G., Widén, E., Willemsen, G., Wilsgaard, T., Winkler, T. W., Wright, A. F., Yerges-Armstrong, L. M., Zhao, J. H., Carola Zillikens, M., Boomsma, D. I., Bouchard, C., Chambers, J. C., Chasman, D. I., Cusi, D., Gansevoort, R. T., Gieger, C., Hansen, T., Hicks, A. A., Hu, F., Hveem, K., Jarvelin, M. R., Kajantie, E., Kooner, J. S., Kuh, D., Kuusisto, J., Laakso, M., Lakka, T. A., Lehtimäki, T., Metspalu, A., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Palmer, L. J., Pedersen, O., Perola, M., Peters, A., Psaty, B. M., Puolijoki, H., Rauramaa, R., Rudan, I., Salomaa, V., Schwarz, P. E. H., Shudiner, A. R., Smit, J. H., Sørensen, T. I. A., Spector, T. D., Stefansson, K., Stumvoll, M., Tremblay, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Völker, U., Vollenweider, P., Wareham, N. J., Watkins, H., Wilson, J. F., Zeggini, E., Abecasis, G. R., Boehnke, M., Borecki, I. B., Deloukas, P., Van Duijn, C. M., Fox, C., Groop, L. C., Heid, I. M., Hunter, D. J., Kaplan, R. C., Mccarthy, M. I., North, K. E., O'connell, J. R., Schlessinger, D., Thorsteinsdottir, U., Strachan, D. P., Frayling, T., Hirschhorn, J. N., Müller-Nurasyid, M. & Loos, R. J. F., Nov 23 2016, In: Nature communications. 7, 13357.

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    60 Scopus citations

  • Assessment of the genetic variance of late-onset Alzheimer's disease

    Alzheimer's Disease Genetics Consortium (ADGC), May 1 2016, In: Neurobiology of Aging. 41, p. 200.e13-200.e20

    Research output: Contribution to journal › Article › peer-review

    Open Access
    64 Scopus citations

  • Association between genetic traits for immune-mediated diseases and Alzheimer disease

    Yokoyama, J. S., Wang, Y., Schork, A. J., Thompson, W. K., Karch, C. M., Cruchaga, C., McEvoy, L. K., Witoelar, A., Chen, C. H., Holland, D., Brewer, J. B., Franke, A., Dillon, W. P., Wilson, D. M., Mukherjee, P., Hess, C. P., Miller, Z., Bonham, L. W., Shen, J. & Rabinovici, G. D. & 8 others, Rosen, H. J., Miller, B. L., Hyman, B. T., Schellenberg, G. D., Karlsen, T. H., Andreassen, O. A., Dale, A. M. & Desikan, R. S., Jun 2016, In: JAMA Neurology. 73, 6, p. 691-697 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    135 Scopus citations

  • Association between serum calcium level and extent of bleeding in patients with intracerebral hemorrhage

    Morotti, A., Charidimou, A., Phuah, C. L., Jessel, M. J., Schwab, K., Ayres, A. M., Romero, J. M., Viswanathan, A., Gurol, M. E., Greenberg, S. M., Anderson, C. D., Rosand, J. & Goldstein, J. N., Nov 1 2016, In: JAMA Neurology. 73, 11, p. 1285-1290 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    88 Scopus citations

  • BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease

    Lim, Y. Y., Hassenstab, J., Cruchaga, C., Goate, A., Fagan, A. M., Benzinger, T. L. S., Maruff, P., Snyder, P. J., Masters, C. L., Allegri, R., Chhatwal, J., Farlow, M. R., Graff-Radford, N. R., Laske, C., Levin, J., McDade, E., Ringman, J. M., Rossor, M., Salloway, S. & Schofield, P. R. & 3 others, Holtzman, D. M., Morris, J. C. & Bateman, R. J., Oct 1 2016, In: Brain. 139, 10, p. 2766-2777 12 p.

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    Open Access
    64 Scopus citations

  • BKCa channel regulates calcium oscillations induced by alpha-2-macroglobulin in human myometrial smooth muscle cells

    Wakle-Prabagaran, M., Lorca, R. A., Ma, X., Stamnes, S. J., Amazu, C., Hsiao, J. J., Karch, C. M., Hyrc, K. L., Wright, M. E. & England, S. K., Apr 19 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 16, p. E2335-E2344

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    Open Access
    20 Scopus citations

  • CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

    Williams, K. L., Topp, S., Yang, S., Smith, B., Fifita, J. A., Warraich, S. T., Zhang, K. Y., Farrawell, N., Vance, C., Hu, X., Chesi, A., Leblond, C. S., Lee, A., Rayner, S. L., Sundaramoorthy, V., Dobson-Stone, C., Molloy, M. P., Van Blitterswijk, M., Dickson, D. W. & Petersen, R. C. & 48 others, Graff-Radford, N. R., Boeve, B. F., Murray, M. E., Pottier, C., Don, E., Winnick, C., McCann, E. P., Hogan, A., Daoud, H., Levert, A., Dion, P. A., Mitsui, J., Ishiura, H., Takahashi, Y., Goto, J., Kost, J., Gellera, C., Gkazi, A. S., Miller, J., Stockton, J., Brooks, W. S., Boundy, K., Polak, M., Muñoz-Blanco, J. L., Esteban-Pérez, J., Rábano, A., Hardiman, O., Morrison, K. E., Ticozzi, N., Silani, V., De Belleroche, J., Glass, J. D., Kwok, J. B. J., Guillemin, G. J., Chung, R. S., Tsuji, S., Brown, R. H., García-Redondo, A., Rademakers, R., Landers, J. E., Gitler, A. D., Rouleau, G. A., Cole, N. J., Yerbury, J. J., Atkin, J. D., Shaw, C. E., Nicholson, G. A. & Blair, I. P., Apr 15 2016, In: Nature communications. 7, 11253.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    171 Scopus citations