Institute for Informatics, Data Science and Biostatistics (I2DB)

2025

A mixed-methods study exploring the benefits, drawbacks, and utilization of data in care: Findings from the EPI-CAL early psychosis learning health care network

Ereshefsky, S., Gemignani, R., Savill, M., Sanford, K. C., Banks, L. M., Tryon, V. L., Nye, K. E., Pierce, K. M., Miles, M. J., Miller, C., Nguyen, K. L. H., Sharma, N., Kado-Walton, M., Hakusui, C. K., Smith, L., Padilla, V. E., McNamara, A. P., Safdar, M., Padovani, A. J. & Loewy, R. L. & 3 others, Wilcox, A. B., Tully, L. M. & Niendam, T. A., Feb 2025, In: Schizophrenia research. 276, p. 157-166 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

Peri-operative mental health interventions for surgical oncology patients: a narrative synthesis and meta-analysis

Abraham, J., Holzer, K. J., Pedamallu, L., Kozower, B. D., Avidan, M. S. & Lenze, E. J., Feb 2025, In: Anaesthesia. 80, S2, p. 54-64 11 p.

Research output: Contribution to journal › Review article › peer-review

Unraveling Heart Failure Phenotypes: A Systematic Review and Meta-analysis of Peak Oxygen Uptake and Its Determinants

Tomczak, C. R., Foulkes, S. J., Weinkauf, C., Walesiak, D., Wang, J., Schmid, V., Paterson, S., Tucker, W. J., Nelson, M. D., Wernhart, S., Vontobel, J., Niederseer, D. & Haykowsky, M. J., Apr 2025, In: CJC Open. 7, 4, p. 367-379 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2024

Artificial Intelligence in Otology and Neurotology

Rapoport, N., Pavelchek, C., Michelson, A. P. & Shew, M. A., Oct 2024, In: Otolaryngologic Clinics of North America. 57, 5, p. 791-802 12 p.

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Determinants of Impaired Peak Oxygen Uptake in Breast Cancer Survivors: JACC: CardioOncology Primer

Foulkes, S. J., Haykowsky, M. J., Li, T., Wang, J., Kennedy, M., Kirkham, A. A., Thompson, R. B., Paterson, D. I., La Gerche, A. & Pituskin, E., Feb 2024, In: JACC: CardioOncology. 6, 1, p. 33-37 5 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

4 Scopus citations

Determining If COPD Self-Management Televisit-Based Interventions Are Evaluated Among and Equitably Effective Across Diverse Patient Populations to Reduce Acute Care Use: A Scoping Review

Akula, M., Nguyen, M., Abraham, J., Arora, V. M., Oladosu, F., Sunderrajan, A., Traeger, L. & Press, V. G., Dec 2024, In: CHEST. 166, 6, p. 1371-1393 23 p.

Research output: Contribution to journal › Review article › peer-review

Endometriosis Typology and Ovarian Cancer Risk

Barnard, M. E., Farland, L. V., Yan, B., Wang, J., Trabert, B., Doherty, J. A., Meeks, H. D., Madsen, M., Guinto, E., Collin, L. J., Maurer, K. A., Page, J. M., Kiser, A. C., Varner, M. W., Allen-Brady, K., Pollack, A. Z., Peterson, K. R., Peterson, C. M. & Schliep, K. C., Dec 1 2024, In: Obstetrical and Gynecological Survey. 79, 12, p. 718-719 2 p.

Research output: Contribution to journal › Review article › peer-review

Evolution of white matter hyperintensity segmentation methods and implementation over the past two decades; an incomplete shift towards deep learning

CSF and Blood, Genetics, Neuropathology, NACC, DIAN, Cerebrovascular Disease (CVD) Risk, Hippocampal Sclerosis (HS-TDP43) Risk, Artificial Intelligence and Machine Learning, for the ADOPIC, ADNI Investigators, Biostats, Database and Bioinformatics, Cognition & Imaging, Oct 2024, In: Brain Imaging and Behavior. 18, 5, p. 1310-1322 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

Machine learning-augmented interventions in perioperative care: a systematic review and meta-analysis

Mehta, D., Gonzalez, X. T., Huang, G. & Abraham, J., Dec 2024, In: British journal of anaesthesia. 133, 6, p. 1159-1172 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

Physiological determinants of decreased peak leg oxygen uptake in chronic disease: a systematic review and meta-analysis

Foulkes, S. J., Wagner, P. D., Wang, J., Gerche, A. L. & Haykowsky, M. J., 2024, In: Journal of Applied Physiology. 136, 6, p. 1293-1302 10 p.

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

The impact of compassion-based interventions on perioperative anxiety and depression: A systematic review and meta-analysis

Holzer, K. J., Bollepalli, H., Carron, J., Yaeger, L. H., Avidan, M. S., Lenze, E. J. & Abraham, J., Nov 15 2024, In: Journal of affective disorders. 365, p. 476-491 16 p.

Research output: Contribution to journal › Review article › peer-review

2023

An evidence synthesis on perioperative Handoffs: A call for balanced sociotechnical solutions

Abraham, J., Duffy, C., Kandasamy, M., France, D. & Greilich, P., Jun 2023, In: International Journal of Medical Informatics. 174, 105038.

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

An overview of optimal designs under a given budget in cluster randomized trials with a binary outcome

Liu, J., Liu, L., James, A. S. & Colditz, G. A., Jul 2023, In: Statistical Methods in Medical Research. 32, 7, p. 1420-1441 22 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

A systematic review of multimodal brain age studies: Uncovering a divergence between model accuracy and utility

Jirsaraie, R. J., Gorelik, A. J., Gatavins, M. M., Engemann, D. A., Bogdan, R., Barch, D. M. & Sotiras, A., Apr 14 2023, In: Patterns. 4, 4, 100712.

Research output: Contribution to journal › Review article › peer-review

Open Access

22 Scopus citations

A systematic review of recurrent firearm injury rates in the United States

Shayan, M., Lew, D., Mancini, M., Foraker, R. E., Doering, M. & Mueller, K. L., Mar 2023, In: Preventive Medicine. 168, 107443.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Electronic health record data quality assessment and tools: a systematic review

Lewis, A. E., Weiskopf, N., Abrams, Z. B., Foraker, R., Lai, A. M., Payne, P. R. O. & Gupta, A., Oct 2023, In: Journal of the American Medical Informatics Association. 30, 10, p. 1730-1740 11 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

43 Scopus citations

Global rural health disparities in Alzheimer's disease and related dementias: State of the science

Wiese, L. A. K., Gibson, A., Guest, M. A., Nelson, A. R., Weaver, R., Gupta, A., Carmichael, O., Lewis, J. P., Lindauer, A., Loi, S., Peterson, R., Radford, K., Rhodus, E. K., Wong, C. G., Zuelsdorff, M., Saidi, L. G., Valdivieso-Mora, E., Franzen, S., Pope, C. N. & Killian, T. S. & 25 others, Shrestha, H. L., Heyn, P. C., Ng, T. K. S., Prusaczyk, B., John, S., Kulshreshtha, A., Sheffler, J. L., Besser, L., Daniel, V., Tolea, M. I., Miller, J., Musyimi, C., Corkey, J., Yank, V., Williams, C. L., Rahemi, Z., Park, J. Y., Magzamen, S., Newton, R. L., Harrington, C., Flatt, J. D., Arora, S., Walter, S., Griffin, P. & Babulal, G. M., Sep 2023, In: Alzheimer's and Dementia. 19, 9, p. 4204-4225 22 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

32 Scopus citations

Perioperative Anxiety and Depression in Older Adults: Epidemiology and Treatment

Srifuengfung, M., Abraham, J., Avidan, M. S. & Lenze, E. J., Nov 2023, In: American Journal of Geriatric Psychiatry. 31, 11, p. 996-1008 13 p.

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

The genetic determinants of recurrent somatic mutations in 43,693 blood genomes

NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Apr 2023, In: Science Advances. 9, 17, eabm4945.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Scopus citations

Using electronic health record audit log data for research: Insights from early efforts

Kannampallil, T. & Adler-Milstein, J., Jan 1 2023, In: Journal of the American Medical Informatics Association. 30, 1, p. 167-171 5 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

16 Scopus citations

What quantifies good primary care in the United States? A review of algorithms and metrics using real-world data

Wang, Y., Zheng, J., Schneberk, T., Ke, Y., Chan, A., Hu, T., Lam, J., Gutierrez, M., Portillo, I., Wu, D., Chang, C. H., Qu, Y., Brown, L. & Nichol, M. B., Dec 2023, In: BMC Primary Care. 24, 1, 130.

Research output: Contribution to journal › Review article › peer-review

Open Access

2022

Antibiotics for Preventing Recurrent Urinary Tract Infection: Systematic Review and Meta-analysis

Jent, P., Berger, J., Kuhn, A., Trautner, B. W., Atkinson, A. & Marschall, J., Jul 1 2022, In: Open Forum Infectious Diseases. 9, 7, ofac327.

Research output: Contribution to journal › Review article › peer-review

Open Access

15 Scopus citations

Around the EQUATOR with clinician-scientists transdisciplinary aging research (Clin-STAR) principles: Implementation science challenges and opportunities

Carpenter, C. R., Southerland, L. T., Lucey, B. P. & Prusaczyk, B., Dec 2022, In: Journal of the American Geriatrics Society. 70, 12, p. 3620-3630 11 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

7 Scopus citations

Effectiveness and Minimum Effective Dose of App-Based Mobile Health Interventions for Anxiety and Depression Symptom Reduction: Systematic Review and Meta-Analysis

Lu, S. C., Xu, M., Wang, M., Hardi, A., Cheng, A. L., Chang, S. H. & Yen, P. Y., Sep 1 2022, In: JMIR Mental Health. 9, 9, e39454.

Research output: Contribution to journal › Review article › peer-review

Open Access

14 Scopus citations

Effect of health information technology (HIT)-based discharge transition interventions on patient readmissions and emergency room visits: A systematic review

Abraham, J., Meng, A., Tripathy, S., Kitsiou, S. & Kannampallil, T., Apr 1 2022, In: Journal of the American Medical Informatics Association. 29, 4, p. 735-748 14 p.

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Emergency Department Communication in Persons Living With Dementia and Care Partners: A Scoping Review

Geriatric Emergency care Applied Research 2.0 Network, Aug 2022, In: Journal of the American Medical Directors Association. 23, 8, p. 1313.e15-1313.e46

Research output: Contribution to journal › Review article › peer-review

Open Access

28 Scopus citations

Generalized linear–quadratic model with a change point due to a covariate threshold

Zhang, F., Yang, J., Liu, L. & Yu, Y., Jan 2022, In: Journal of Statistical Planning and Inference. 216, p. 194-206 13 p.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health: A Presidential Advisory from the American Heart Association

Lloyd-Jones, D. M., Allen, N. B., Anderson, C. A. M., Black, T., Brewer, L. C., Foraker, R. E., Grandner, M. A., Lavretsky, H., Perak, A. M., Sharma, G. & Rosamond, W., Aug 2 2022, In: Circulation. 146, 5, p. E18-E43

Research output: Contribution to journal › Review article › peer-review

Open Access

1327 Scopus citations

The HERITAGE Family Study: A Review of the Effects of Exercise Training on Cardiometabolic Health, with Insights into Molecular Transducers

Sarzynski, M. A., Rice, T. K., Després, J. P., Pérusse, L., Tremblay, A., Stanforth, P. R., Tchernof, A., Barber, J. L., Falciani, F., Clish, C., Robbins, J. M., Ghosh, S., Gerszten, R. E., Leon, A. S., Skinner, J. S., Rao, D. C. & Bouchard, C., May 1 2022, In: Medicine and Science in Sports and Exercise. 54, 5, p. S1-S43

Research output: Contribution to journal › Review article › peer-review

Open Access

33 Scopus citations

Translating Data Analytics Into Improved Spine Surgery Outcomes: A Roadmap for Biomedical Informatics Research in 2021

Greenberg, J. K., Otun, A., Ghogawala, Z., Yen, P.-Y., Molina, C. A., Limbrick, D. D., Foraker, R., Kelly, M. P. & Ray, W. Z., Jun 2022, In: Global Spine Journal. 12, 5, p. 952-963 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

4 Scopus citations

2021

Achieving Optimal Population Cardiovascular Health Requires an Interdisciplinary Team and a Learning Healthcare System A Scientific Statement From the American Heart Association

Foraker, R. E., Benziger, C. P., Debarmore, B. M., Cené, C. W., Loustalot, F., Khan, Y., Anderson, C. A. M. & Roger, V. L., Jan 12 2021, In: Circulation. 143, 2, p. E9-E18

Research output: Contribution to journal › Review article › peer-review

Open Access

23 Scopus citations

Artificial intelligence: A powerful paradigm for scientific research

Xu, Y., Liu, X., Cao, X., Huang, C., Liu, E., Qian, S., Liu, X., Wu, Y., Dong, F., Qiu, C. W., Qiu, J., Hua, K., Su, W., Wu, J., Xu, H., Han, Y., Fu, C., Yin, Z., Liu, M. & Roepman, R. & 28 others, Dietmann, S., Virta, M., Kengara, F., Zhang, Z., Zhang, L., Zhao, T., Dai, J., Yang, J., Lan, L., Luo, M., Liu, Z., An, T., Zhang, B., He, X., Cong, S., Liu, X., Zhang, W., Lewis, J. P., Tiedje, J. M., Wang, Q., An, Z., Wang, F., Zhang, L., Huang, T., Lu, C., Cai, Z., Wang, F. & Zhang, J., Nov 28 2021, In: The Innovation. 2, 4, 100179.

Research output: Contribution to journal › Review article › peer-review

Open Access

853 Scopus citations

Building on diana forsythe's legacy: The value of human experience and context in biomedical and health informatics

Unertl, K. M., Abraham, J. & Bakken, S., Feb 1 2021, In: Journal of the American Medical Informatics Association. 28, 2, p. 197-208 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

Comparison of early warning scores for sepsis early identification and prediction in the general ward setting

Yu, S. C., Shivakumar, N., Betthauser, K., Gupta, A., Lai, A. M., Kollef, M. H., Payne, P. R. O. & Michelson, A. P., Jul 1 2021, In: JAMIA Open. 4, 3, ooab062.

Research output: Contribution to journal › Review article › peer-review

Open Access

15 Scopus citations

Getting More Precise in Public Messaging on Scientific and Data Uncertainties for Precision Medicine Research

Ma, J. & Kannampallil, T., Nov 1 2021, In: Annals of Behavioral Medicine. 55, 11, p. 1045-1047 3 p.

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Harnessing technological solutions for childhood obesity prevention and treatment: a systematic review and meta-analysis of current applications

Fowler, L. A., Grammer, A. C., Staiano, A. E., Fitzsimmons-Craft, E. E., Chen, L., Yaeger, L. H. & Wilfley, D. E., May 2021, In: International Journal of Obesity. 45, 5, p. 957-981 25 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

44 Scopus citations

Machine learning for modeling the progression of Alzheimer disease dementia using clinical data: A systematic literature review

Kumar, S., Oh, I., Schindler, S., Lai, A., Payne, P. R. O. & Gupta, A., Jul 1 2021, In: JAMIA Open. 4, 3, ooab052.

Research output: Contribution to journal › Review article › peer-review

Open Access

57 Scopus citations

Precision clinical trials: A framework for getting to precision medicine for neurobehavioural disorders

Lenze, E. J., Nicol, G. E., Barbour, D. L., Kannampallil, T., Wong, A. W. K., Piccirillo, J., Drysdale, A. T., Sylvester, C. M., Haddad, R., Miller, J. P., Low, C. A., Lenze, S. N., Freedland, K. E. & Rodebaugh, T. L., Jan 1 2021, In: Journal of Psychiatry and Neuroscience. 46, 1, p. 97-110 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

29 Scopus citations

Predicting self-intercepted medication ordering errors using machine learning

King, C. R., Abraham, J., Fritz, B. A., Cui, Z., Galanter, W., Chen, Y. & Kannampallil, T., Jul 2021, In: PloS one. 16, 7 July, e0254358.

Research output: Contribution to journal › Review article › peer-review

Open Access

7 Scopus citations

Systematic review and meta-analysis of interventions for operating room to intensive care unit handoffs

Abraham, J., Meng, A., Tripathy, S., Avidan, M. S. & Kannampallil, T., Feb 9 2021, In: BMJ Quality and Safety. 30, 6, p. 513-524 12 p.

Research output: Contribution to journal › Review article › peer-review

32 Scopus citations

Technologies and perspectives for achieving carbon neutrality

Wang, F., Harindintwali, J. D., Yuan, Z., Wang, M., Wang, F., Li, S., Yin, Z., Huang, L., Fu, Y., Li, L., Chang, S. X., Zhang, L., Rinklebe, J., Yuan, Z., Zhu, Q., Xiang, L., Tsang, D. C. W., Xu, L., Jiang, X. & Liu, J. & 38 others, Wei, N., Kästner, M., Zou, Y., Ok, Y. S., Shen, J., Peng, D., Zhang, W., Barceló, D., Zhou, Y., Bai, Z., Li, B., Zhang, B., Wei, K., Cao, H., Tan, Z., Zhao, L. B., He, X., Zheng, J., Bolan, N., Liu, X., Huang, C., Dietmann, S., Luo, M., Sun, N., Gong, J., Gong, Y., Brahushi, F., Zhang, T., Xiao, C., Li, X., Chen, W., Jiao, N., Lehmann, J., Zhu, Y. G., Jin, H., Schäffer, A., Tiedje, J. M. & Chen, J. M., Nov 28 2021, In: The Innovation. 2, 4, 100180.

Research output: Contribution to journal › Review article › peer-review

Open Access

1025 Scopus citations

Ten principles for data sharing and commercialization

Cole, C. L., Sengupta, S., Rossetti, S., Vawdrey, D. K., Halaas, M., Maddox, T. M., Gordon, G., Dave, T., Payne, P. R. O., Williams, A. E. & Estrin, D., Mar 1 2021, In: Journal of the American Medical Informatics Association. 28, 3, p. 646-649 4 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

17 Scopus citations

The Pseudo Maximum Likelihood Estimator for Quantiles of Survey Variables

Wang, J., Feb 1 2021, In: Journal of Survey Statistics and Methodology. 9, 1, p. 185-201 17 p.

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Timing of antibiotic therapy in the ICU

Kollef, M. H., Shorr, A. F., Bassetti, M., Timsit, J. F., Micek, S. T., Michelson, A. P. & Garnacho-Montero, J., Dec 2021, In: Critical Care. 25, 1, 360.

Research output: Contribution to journal › Review article › peer-review

Open Access

86 Scopus citations

Use of electronic health records to support a public health response to the COVID-19 pandemic in the United States: A perspective from 15 academic medical centers

Madhavan, S., Bastarache, L., Brown, J. S., Butte, A. J., Dorr, D. A., Embi, P. J., Friedman, C. P., Johnson, K. B., Moore, J. H., Kohane, I. S., Payne, P. R. O., Tenenbaum, J. D., Weiner, M. G., Wilcox, A. B. & Ohno-Machado, L., Feb 1 2021, In: Journal of the American Medical Informatics Association. 28, 2, p. 393-401 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

59 Scopus citations

2020

Approaches to Defining Common and Dissociable Neurobiological Deficits Associated With Psychopathology in Youth

Kaczkurkin, A. N., Moore, T. M., Sotiras, A., Xia, C. H., Shinohara, R. T. & Satterthwaite, T. D., Jul 1 2020, In: Biological Psychiatry. 88, 1, p. 51-62 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access