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  • 2016

    Differential risks for adverse outcomes 3 years after kidney transplantation based on initial immunosuppression regimen: a national study

    Dharnidharka, V. R., Schnitzler, M. A., Chen, J., Brennan, D. C., Axelrod, D., Segev, D. L., Schechtman, K. B., Zheng, J. & Lentine, K. L., Nov 1 2016, In: Transplant International. 29, 11, p. 1226-1236 11 p.

    Research output: Contribution to journal › Article › peer-review

    42 Scopus citations

  • Disability progression after switching from natalizumab to fingolimod or interferon beta/glatiramer acetate therapies: A NARCOMS analysis

    Cofield, S. S., Fox, R. J., Tyry, T., Salter, A. R. & Campagnolo, D., 2016, In: International Journal of MS Care. 18, 5, p. 230-238 9 p.

    Research output: Contribution to journal › Article › peer-review

    4 Scopus citations

  • DNA methylation of oxidative stress genes and cancer risk in the Normative Aging Study

    Gao, T., Joyce, B. T., Liu, L., Zheng, Y., Dai, Q., Zhang, Z., Zhang, W., Shrubsole, M. J., Tao, M. H., Schwartz, J., Baccarelli, A. & Hou, L., 2016, In: American Journal of Cancer Research. 6, 2, p. 553-561 9 p.

    Research output: Contribution to journal › Article › peer-review

    14 Scopus citations

  • Drug repurposing hypothesis generation using the "RE:fine drugs" system

    Regan, K., Moosavinasab, S., Payne, P. & Lin, S., Dec 11 2016, In: Journal of Visualized Experiments. 2016, 118, e54948.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    3 Scopus citations

  • Efficacy and safety of deflazacort vs prednisone and placebo for Duchenne muscular dystrophy

    Griggs, R. C., Miller, J. P., Greenberg, C. R., Fehlings, D. L., Pestronk, A., Mendell, J. R., Moxley, R. T., King, W., Kissel, J. T., Cwik, V., Vanasse, M., Florence, J. M., Pandya, S., Dubow, J. S. & Meyer, J. M., Nov 15 2016, In: Neurology. 87, 20, p. 2123-2131 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    115 Scopus citations

  • Electronic health record-based assessment of cardiovascular health: The stroke prevention in healthcare delivery environments (SPHERE) study

    Foraker, R. E., Shoben, A. B., Kelley, M. M., Lai, A. M., Lopetegui, M. A., Jackson, R. D., Langan, M. A. & Payne, P. R. O., Dec 1 2016, In: Preventive Medicine Reports. 4, p. 303-308 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Scopus citations

  • Examining the joint effect of disability, health behaviors, and comorbidity on mortality in MS

    Salter, A., Tyry, T., Wang, G., Fox, R. J., Cutter, G. & Marrie, R. A., Oct 1 2016, In: Neurology: Clinical Practice. 6, 5, p. 397-408 12 p.

    Research output: Contribution to journal › Article › peer-review

    19 Scopus citations

  • Exploring the feasibility and acceptability of sensor monitoring of gait and falls in the homes of persons with multiple sclerosis

    Newland, P., Wagner, J. M., Salter, A., Thomas, F. P., Skubic, M. & Rantz, M., Sep 1 2016, In: Gait and Posture. 49, p. 277-282 6 p.

    Research output: Contribution to journal › Article › peer-review

    14 Scopus citations

  • Expression of TIA1 and PAX5 in Classical Hodgkin Lymphoma at Initial Diagnosis May Predict Clinical Outcome

    Nguyen, T. D. T., Frater, J. L., Klein, J., Chen, L., Bartlett, N. L., Foyil, K. V. & Kreisel, F. H., Jul 1 2016, In: Applied Immunohistochemistry and Molecular Morphology. 24, 6, p. 383-391 9 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations

  • Folate-conjugated immunoglobulin targets melanoma tumor cells for NK cell effector functions

    Skinner, C. C., McMichael, E. L., Jaime-Ramirez, A. C., Abrams, Z. B., Lee, R. J. & Carson, W. E., Aug 1 2016, In: Melanoma Research. 26, 4, p. 329-337 9 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations

  • Genetic association of left ventricular mass assessed by M-mode and two-dimensional echocardiography

    Barve, R. A., Gu, C. C., Yang, W., Chu, J., Dávila-Román, V. G. & De Las Fuentes, L., Jan 1 2016, In: Journal of Hypertension. 34, 1, p. 88-96 9 p.

    Research output: Contribution to journal › Article › peer-review

    5 Scopus citations

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Pattaro, C., Teumer, A., Gorski, M., Chu, A. Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M. H., Pers, T. H., Johnson, A. D., Ko, Y. A., Fuchsberger, C., Tayo, B., & 678 othersNalls, M., Feitosa, M. F., Isaacs, A., Dehghan, A., D'Adamo, P., Adeyemo, A., Dieffenbach, A. K., Zonderman, A. B., Nolte, I. M., Van Der Most, P. J., Wright, A. F., Shuldiner, A. R., Morrison, A. C., Hofman, A., Smith, A. V., Dreisbach, A. W., Franke, A., Uitterlinden, A. G., Metspalu, A., Tonjes, A., Lupo, A., Robino, A., Johansson, Å., Demirkan, A., Kollerits, B., Freedman, B. I., Ponte, B., Oostra, B. A., Paulweber, B., Krämer, B. K., Mitchell, B. D., Buckley, B. M., Peralta, C. A., Hayward, C., Helmer, C., Rotimi, C. N., Shaffer, C. M., Müller, C., Sala, C., Van Duijn, C. M., Saint-Pierre, A., Ackermann, D., Shriner, D., Ruggiero, D., Toniolo, D., Lu, Y., Cusi, D., Czamara, D., Ellinghaus, D., Siscovick, D. S., Ruderfer, D., Gieger, C., Grallert, H., Rochtchina, E., Atkinson, E. J., Holliday, E. G., Boerwinkle, E., Salvi, E., Bottinger, E. P., Murgia, F., Rivadeneira, F., Ernst, F., Kronenberg, F., Hu, F. B., Navis, G. J., Curhan, G. C., Ehret, G. B., Homuth, G., Coassin, S., Thun, G. A., Pistis, G., Gambaro, G., Malerba, G., Montgomery, G. W., Eiriksdottir, G., Jacobs, G., Li, G., Wichmann, H. E., Campbell, H., Schmidt, H., Wallaschofski, H., Völzke, H., Brenner, H., Kroemer, H. K., Kramer, H., Lin, H., Leach, I. M., Ford, I., Guessous, I., Rudan, I., Prokopenko, I., Borecki, I., Heid, I. M., Kolcic, I., Persico, I., Jukema, J. W., Wilson, J. F., Felix, J. F., Divers, J., Lambert, J. C., Stafford, J. M., Gaspoz, J. M., Smith, J. A., Faul, J. D., Wang, J. J., Ding, J., Hirschhorn, J. N., Attia, J., Whitfield, J. B., Chalmers, J., Viikari, J., Coresh, J., Denny, J. C., Karjalainen, J., Fernandes, J. K., Endlich, K., Butterbach, K., Keene, K. L., Lohman, K., Portas, L., Launer, L. J., Lyytikäinen, L. P., Yengo, L., Franke, L., Ferrucci, L., Rose, L. M., Kedenko, L., Rao, M., Struchalin, M., Kleber, M. E., Cavalieri, M., Haun, M., Cornelis, M. C., Ciullo, M., Pirastu, M., De Andrade, M., McEvoy, M. A., Woodward, M., Adam, M., Cocca, M., Nauck, M., Imboden, M., Waldenberger, M., Pruijm, M., Metzger, M., Stumvoll, M., Evans, M. K., Sale, M. M., Kähönen, M., Boban, M., Bochud, M., Rheinberger, M., Verweij, N., Bouatia-Naji, N., Martin, N. G., Hastie, N., Probst-Hensch, N., Soranzo, N., Devuyst, O., Raitakari, O., Gottesman, O., Franco, O. H., Polasek, O., Gasparini, P., Munroe, P. B., Ridker, P. M., Mitchell, P., Muntner, P., Meisinger, C., Smit, J. H., Abecasis, G. R., Adair, L. S., Alexander, M., Altshuler, D., Amin, N., Arking, D. E., Arora, P., Aulchenko, Y., Bakker, S. J. L., Bandinelli, S., Barroso, I., Beckmann, J. S., Beilby, J. P., Bergman, R. N., Bergmann, S., Bis, J. C., Boehnke, M., Bonnycastle, L. L., Bornstein, S. R., Bots, M. L., Bragg-Gresham, J. L., Brand, S. M., Brand, E., Braund, P. S., Brown, M. J., Burton, P. R., Casas, J. P., Caulfield, M. J., Chakravarti, A., Chambers, J. C., Chandak, G. R., Chang, Y. P. C., Charchar, F. J., Chaturvedi, N., Cho, Y. S., Clarke, R., Collins, F. S., Collins, R., Connell, J. M., Cooper, J. A., Cooper, M. N., Cooper, R. S., Corsi, A. M., Dörr, M., Dahgam, S., Danesh, J., Smith, G. D., Day, I. N. M., Deloukas, P., Denniff, M., Dominiczak, A. F., Dong, Y., Doumatey, A., Elliott, P., Elosua, R., Erdmann, J., Eyheramendy, S., Farrall, M., Fava, C., Forrester, T., Fowkes, F. G. R., Fox, E. R., Frayling, T. M., Galan, P., Ganesh, S. K., Garcia, M., Gaunt, T. R., Glazer, N. L., Go, M. J., Goel, A., Grässler, J., Grobbee, D. E., Groop, L., Guarrera, S., Guo, X., Hadley, D., Hamsten, A., Han, B. G., Hardy, R., Hartikainen, A. L., Heath, S., Heckbert, S. R., Hedblad, B., Hercberg, S., Hernandez, D., Hicks, A. A., Hilton, G., Hingorani, A. D., Hoffman Bolton, J. A., Hopewell, J. C., Howard, P., Humphries, S. E., Hunt, S. C., Hveem, K., Ikram, M. A., Islam, M., Iwai, N., Jarvelin, M. R., Jackson, A. U., Jafar, T. H., Janipalli, C. S., Johnson, T., Kathiresan, S., Khaw, K. T., Kim, H. L., Kinra, S., Kita, Y., Kivimaki, M., Kooner, J. S., Kumar, M. J. K., Kuh, D., Kulkarni, S. R., Kumari, M., Kuusisto, J., Kuznetsova, T., Laakso, M., Laan, M., Laitinen, J., Lakatta, E. G., Langefeld, C. D., Larson, M. G., Lathrop, M., Lawlor, D. A., Lawrence, R. W., Lee, J. Y., Lee, N. R., Levy, D., Li, Y., Longstreth, W. T., Luan, J., Lucas, G., Ludwig, B., Mangino, M., Mani, K. R., Marmot, M. G., Mattace-Raso, F. U. S., Matullo, G., McArdle, W. L., McKenzie, C. A., Meitinger, T., Melander, O., Meneton, P., Meschia, J. F., Miki, T., Milaneschi, Y., Mohlke, K. L., Mooser, V., Morken, M. A., Morris, R. W., Mosley, T. H., Najjar, S., Narisu, N., Newton-Cheh, C., Nguyen, K. D. H., Nilsson, P., Nyberg, F., O'Donnell, C. J., Ogihara, T., Ohkubo, T., Okamura, T., Ong, R. T. H., Ongen, H., Onland-Moret, N. C., O'Reilly, P. F., Org, E., Orru, M., Palmas, W., Palmen, J., Palmer, L. J., Palmer, N. D., Parker, A. N., Peden, J. F., Peltonen, L., Perola, M., Pihur, V., Platou, C. G. P., Plump, A., Prabhakaran, D., Psaty, B. M., Raffel, L. J., Rao, D. C., Rasheed, A., Ricceri, F., Rice, K. M., Rosengren, A., Rotter, J. I., Rudock, M. E., Sõber, S., Salako, T., Saleheen, D., Salomaa, V., Samani, N. J., Schwartz, S. M., Schwarz, P. E. H., Scott, L. J., Scott, J., Scuteri, A., Sehmi, J. S., Seielstad, M., Seshadri, S., Sharma, P., Shaw-Hawkins, S., Shi, G., Shrine, N. R. G., Sijbrands, E. J. G., Sim, X., Singleton, A., Sjögren, M., Smith, N. L., Artigas, M. S., Spector, T. D., Staessen, J. A., Stancakova, A., Steinle, N. I., Strachan, D. P., Stringham, H. M., Sun, Y. V., Swift, A. J., Tabara, Y., Tai, E. S., Talmud, P. J., Taylor, A., Terzic, J., Thelle, D. S., Tobin, M. D., Tomaszewski, M., Tripathy, V., Tuomilehto, J., Tzoulaki, I., Uda, M., Ueshima, H., Uiterwaal, C. S. P. M., Umemura, S., Van Der Harst, P., Van Der Schouw, Y. T., Van Gilst, W. H., Vartiainen, E., Vasan, R. S., Veldre, G., Verwoert, G. C., Viigimaa, M., Vinay, D. G., Vineis, P., Voight, B. F., Vollenweider, P., Wagenknecht, L. E., Wain, L. V., Wang, X., Wang, T. J., Wareham, N. J., Watkins, H., Weder, A. B., Whincup, P. H., Wiggins, K. L., Witteman, J. C. M., Wong, A., Wu, Y., Yajnik, C. S., Yao, J., Young, J. H., Zelenika, D., Zhai, G., Zhang, W., Zhang, F., Zhao, J. H., Zhu, H., Zhu, X., Zitting, P., Zukowska-Szczechowska, E., Okada, Y., Wu, J. Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S. C., Wong, T. Y., Liu, J., Young, T. L., Aung, T., Teo, Y. Y., Kim, Y. J., Kang, D., Chen, C. H., Tsai, F. J., Chang, L. C., Fann, S. J. C., Mei, H., Hixson, J. E., Chen, S., Katsuya, T., Isono, M., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y. T., Tanaka, T., Reilly, M. P., Schunkert, H., Assimes, T. L., Hall, A., Hengstenberg, C., König, I. R., Laaksonen, R., McPherson, R., Thompson, J. R., Thorsteinsdottir, U., Ziegler, A., Absher, D., Chen, L., Cupples, L. A., Halperin, E., Li, M., Musunuru, K., Preuss, M., Schillert, A., Thorleifsson, G., Wells, G. A., Holm, H., Roberts, R., Stewart, A. F. R., Fortmann, S., Go, A., Hlatky, M., Iribarren, C., Knowles, J., Myers, R., Quertermous, T., Sidney, S., Risch, N., Tang, H., Blankenberg, S., Schnabel, R., Sinning, C., Lackner, K. J., Tiret, L., Nicaud, V., Cambien, F., Bickel, C., Rupprecht, H. J., Perret, C., Proust, C., Münzel, T. F., Barbalic, M., Chen, I. Y. D., Demissie-Banjaw, S., Folsom, A., Lumley, T., Marciante, K., Taylor, K. D., Volcik, K., Gretarsdottir, S., Gulcher, J. R., Kong, A., Stefansson, K., Thorgeirsson, G., Andersen, K., Fischer, M., Grosshennig, A., Linsel-Nitschke, P., Stark, K., Schreiber, S., Aherrahrou, Z., Bruse, P., Doering, A., Klopp, N., Diemert, P., Loley, C., Medack, A., Nahrstedt, J., Peters, A., Wagner, A. K., Willenborg, C., Böhm, B. O., Dobnig, H., Grammer, T. B., Hoffmann, M. M., Meinitzer, A., Winkelmann, B. R., Pilz, S., Renner, W., Scharnagl, H., Stojakovic, T., Tomaschitz, A., Winkler, K., Guiducci, C., Burtt, N., Gabriel, S. B., Dandona, S., Jarinova, O., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H. H., Devaney, J., Burnett, M. S., Pichard, A. D., Kent, K. M., Satler, L., Lindsay, J. M., Waksman, R., Knouff, C. W., Waterworth, D. M., Walker, M. C., Epstein, S. E., Rader, D. J., Nelson, C. P., Wright, B. J., Balmforth, A. J., Ball, S. G., Loehr, L. R., Rosamond, W. D., Benjamin, E., Haritunians, T., Couper, D., Murabito, J., Wang, Y. A., Stricker, B. H., Chang, P. P., Willerson, J. T., Felix, S. B., Watzinger, N., Aragam, J., Zweiker, R., Lind, L., Rodeheffer, R. J., Greiser, K. H., Deckers, J. W., Stritzke, J., Ingelsson, E., Kullo, I., Haerting, J., Reffelmann, T., Redfield, M. M., Werdan, K., Mitchell, G. F., Arnett, D. K., Gottdiener, J. S., Blettner, M., Friedrich, N., Kovacs, P., Wild, P. S., Froguel, P., Rettig, R., Mägi, R., Biffar, R., Schmidt, R., Middelberg, R. P. S., Carroll, R. J., Penninx, B. W., Scott, R. J., Katz, R., Sedaghat, S., Wild, S. H., Kardia, S. L. R., Ulivi, S., Hwang, S. J., Enroth, S., Kloiber, S., Trompet, S., Stengel, B., Hancock, S. J., Turner, S. T., Rosas, S. E., Stracke, S., Harris, T. B., Zeller, T., Zemunik, T., Lehtimäki, T., Illig, T., Aspelund, T., Nikopensius, T., Esko, T., Tanaka, T., Gyllensten, U., Völker, U., Emilsson, V., Vitart, V., Aalto, V., Gudnason, V., Chouraki, V., Chen, W. M., Igl, W., März, W., Koenig, W., Lieb, W., Loos, R. J. F., Liu, Y., Snieder, H., Pramstaller, P. P., Parsa, A., O'Connell, J. R., Susztak, K., Hamet, P., Tremblay, J., De Boer, I. H., Böger, C. A., Goessling, W., Chasman, D. I., Köttgen, A., Kao, W. H. L. & Fox, C. S., Jan 21 2016, In: Nature communications. 7, 10023.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    336 Scopus citations

  • Genetics and population analysis: Estimating and testing high-dimensional mediation effects in epigenetic studies

    Zhang, H., Zheng, Y., Zhang, Z., Gao, T., Joyce, B., Yoon, G., Zhang, W., Schwartz, J., Just, A., Colicino, E., Vokonas, P., Zhao, L., Lv, J., Baccarelli, A., Hou, L. & Liu, L., Oct 15 2016, In: Bioinformatics. 32, 20, p. 3150-3154 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    83 Scopus citations

  • Genetic Susceptibility to Lipid Levels and Lipid Change over Time and Risk of Incident Hyperlipidemia in Chinese Populations

    Lu, X., Huang, J., Mo, Z., He, J., Wang, L., Yang, X., Tan, A., Chen, S., Chen, J., Charles Gu, C., Chen, J., Li, Y., Zhao, L., Li, H., Hao, Y., Li, J., Hixson, J. E., Li, Y., Cheng, M., Liu, X., & 18 othersCao, J., Liu, F., Huang, C., Shen, C., Shen, J., Yu, L., Xu, L., Mu, J., Wu, X., Ji, X., Guo, D., Zhou, Z., Yang, Z., Wang, R., Yang, J., Yan, W., Peng, X. & Gu, D., Feb 1 2016, In: Circulation: Cardiovascular Genetics. 9, 1, p. 37-44 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    44 Scopus citations

  • Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference

    Wen, W., Kato, N., Hwang, J. Y., Guo, X., Tabara, Y., Li, H., Dorajoo, R., Yang, X., Tsai, F. J., Li, S., Wu, Y., Wu, T., Kim, S., Guo, X., Liang, J., Shungin, D., Adair, L. S., Akiyama, K., Allison, M., Cai, Q., & 56 othersChang, L. C., Chen, C. H., Chen, Y. T., Cho, Y. S., Choi, B. Y., Gao, Y., Go, M. J., Gu, D., Han, B. G., He, M., Hixson, J. E., Hu, Y., Huang, T., Isono, M., Jung, K. J., Kang, D., Kim, Y. J., Kita, Y., Lee, J., Lee, N. R., Lee, J., Wang, Y., Liu, J. J., Long, J., Moon, S., Nakamura, Y., Nakatochi, M., Ohnaka, K., Rao, D., Shi, J., Sull, J. W., Tan, A., Ueshima, H., Wu, C., Xiang, Y. B., Yamamoto, K., Yao, J., Ye, X., Yokota, M., Zhang, X., Zheng, Y., Qi, L., Rotter, J. I., Jee, S. H., Lin, D., Mohlke, K. L., He, J., Mo, Z., Wu, J. Y., Tai, E. S., Lin, X., Miki, T., Kim, B. J., Takeuchi, F., Zheng, W. & Shu, X. O., Jan 20 2016, In: Scientific reports. 6, 17958.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    48 Scopus citations

  • Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat

    Sung, Y. J., Pérusse, L., Sarzynski, M. A., Fornage, M., Sidney, S., Sternfeld, B., Rice, T., Terry, J. G., Jacobs, D. R., Katzmarzyk, P., Curran, J. E., Jeffrey Carr, J., Blangero, J., Ghosh, S., Després, J. P., Rankinen, T., Rao, D. C. & Bouchard, C., Apr 1 2016, In: International Journal of Obesity. 40, 4, p. 662-674 13 p.

    Research output: Contribution to journal › Article › peer-review

    71 Scopus citations

  • Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study

    Li, C., He, J., Chen, J., Zhao, J., Gu, D., Hixson, J. E., Rao, D. C., Jaquish, C. E., Gu, C. C., Chen, J., Huang, J., Chen, S. & Kelly, T. N., Aug 1 2016, In: Hypertension. 68, 2, p. 348-355 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    36 Scopus citations

  • Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

    Kilpeläinen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, Å. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L. P., Eriksson, J., & 157 othersHenneman, P., Lahti, J., Tanaka, T., Luan, J., Fabiola Del, G. M., Pasko, D., Renström, F., Willems, S. M., Mahajan, A., Rose, L. M., Guo, X., Liu, Y., Kleber, M. E., Pérusse, L., Gaunt, T., Ahluwalia, T. S., Ju Sung, Y., Ramos, Y. F., Amin, N., Amuzu, A., Barroso, I., Bellis, C., Blangero, J., Buckley, B. M., Böhringer, S., I Chen, Y. D., De Craen, A. J. N., Crosslin, D. R., Dale, C. E., Dastani, Z., Day, F. R., Deelen, J., Delgado, G. E., Demirkan, A., Finucane, F. M., Ford, I., Garcia, M. E., Gieger, C., Gustafsson, S., Hallmans, G., Hankinson, S. E., Havulinna, A. S., Herder, C., Hernandez, D., Hicks, A. A., Hunter, D. J., Illig, T., Ingelsson, E., Ioan-Facsinay, A., Jansson, J. O., Jenny, N. S., Jørgensen, M. E., Jørgensen, T., Karlsson, M., Koenig, W., Kraft, P., Kwekkeboom, J., Laatikainen, T., Ladwig, K. H., Leduc, C. A., Lowe, G., Lu, Y., Marques-Vidal, P., Meisinger, C., Menni, C., Morris, A. P., Myers, R. H., Männistö, S., Nalls, M. A., Paternoster, L., Peters, A., Pradhan, A. D., Rankinen, T., Rasmussen-Torvik, L. J., Rathmann, W., Rice, T. K., Brent Richards, J., Ridker, P. M., Sattar, N., Savage, D. B., Söderberg, S., Timpson, N. J., Vandenput, L., Van Heemst, D., Uh, H. W., Vohl, M. C., Walker, M., Wichmann, H. E., Widén, E., Wood, A. R., Yao, J., Zeller, T., Zhang, Y., Meulenbelt, I., Kloppenburg, M., Astrup, A., Sørensen, T. I. A., Sarzynski, M. A., Rao, D. C., Jousilahti, P., Vartiainen, E., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Kajantie, E., Osmond, C., Palotie, A., Eriksson, J. G., Heliövaara, M., Knekt, P. B., Koskinen, S., Jula, A., Perola, M., Huupponen, R. K., Viikari, J. S., Kähönen, M., Lehtimäki, T., Raitakari, O. T., Mellström, D., Lorentzon, M., Casas, J. P., Bandinelli, S., März, W., Isaacs, A., Van Dijk, K. W., Van Duijn, C. M., Harris, T. B., Bouchard, C., Allison, M. A., Chasman, D. I., Ohlsson, C., Lind, L., Scott, R. A., Langenberg, C., Wareham, N. J., Ferrucci, L., Frayling, T. M., Pramstaller, P. P., Borecki, I. B., Waterworth, D. M., Bergmann, S., Waeber, G., Vollenweider, P., Vestergaard, H., Hansen, T., Pedersen, O., Hu, F. B., Eline Slagboom, P., Grallert, H., Spector, T. D., Jukema, J. W., Klein, R. J., Schadt, E. E., Franks, P. W., Lindgren, C. M., Leibel, R. L. & Loos, R. J. F., Feb 1 2016, In: Nature communications. 7, 10494.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    130 Scopus citations

  • Global microRNA profiling for diagnostic appraisal of melanocytic Spitz tumors

    Latchana, N., Regan, K., Howard, J. H., Aldrink, J. H., Ranalli, M. A., Peters, S. B., Zhang, X., Gru, A., Payne, P. R. O., Suarez-Kelly, L. P. & Carson, W. E., Oct 1 2016, In: Journal of Surgical Research. 205, 2, p. 350-358 9 p.

    Research output: Contribution to journal › Article › peer-review

    17 Scopus citations

  • Health insurance affects the use of disease-modifying therapy in multiple sclerosis

    Wang, G., Marrie, R. A., Salter, A. R., Fox, R., Cofield, S. S., Tyry, T. & Cutter, G. R., Jul 26 2016, In: Neurology. 87, 4, p. 365-374 10 p.

    Research output: Contribution to journal › Article › peer-review

    25 Scopus citations

  • Health insurance trajectories and long-term survival after heart transplantation

    Tumin, D., Foraker, R. E., Smith, S., Tobias, J. D. & Hayes, D., Sep 1 2016, In: Circulation: Cardiovascular Quality and Outcomes. 9, 5, p. 576-584 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations

  • Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

    Harrison, J. S., Cornett, E. M., Goldfarb, D., Darosa, P. A., Li, Z. M., Yan, F., Dickson, B. M., Guo, A. H., Cantu, D. V., Kaustov, L., Brown, P. J., Arrowsmith, C. H., Erie, D. A., Major, M. B., Klevit, R. E., Krajewski, K., Kuhlman, B., Strahl, B. D. & Rothbart, S. B., Sep 6 2016, In: eLife. 5, Se, e17101.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    92 Scopus citations

  • High-fidelity analysis of perioperative QTc prolongation

    Duma, A., Pal, S., Helsten, D., Stein, P. K., Miller, J. P. & Nagele, P., Feb 1 2016, In: Anesthesia and analgesia. 122, 2, p. 439-448 10 p.

    Research output: Contribution to journal › Article › peer-review

    12 Scopus citations

  • Human epithelial NA+ channel missense variants identified in the GenSalt study alter channel activity

    Ray, E. C., Chen, J., Kelly, T. N., He, J., Hamm, L. L., Gu, D., Shimmin, L. C., Hixson, J. E., Rao, D. C., Sheng, S. & Kleyman, T. R., 2016, In: American Journal of Physiology - Renal Physiology. 311, 5, p. F908-F914

    Research output: Contribution to journal › Article › peer-review

    Open Access
    18 Scopus citations

  • Identification and characterization of MCM3 as a kelch-like ECH-associated protein 1 (KEAP1) substrate

    Mulvaney, K. M., Matson, J. P., Siesser, P. F., Tamir, T. Y., Goldfarb, D., Jacobs, T. M., Cloer, E. W., Harrison, J. S., Vaziri, C., Cook, J. G. & Major, M. B., Nov 4 2016, In: Journal of Biological Chemistry. 291, 45, p. 23719-23733 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    62 Scopus citations

  • Imaging and cerebrospinal fluid biomarkers in early preclinical alzheimer disease

    Vlassenko, A. G., McCue, L., Jasielec, M. S., Su, Y., Gordon, B. A., Xiong, C., Holtzman, D. M., Benzinger, T. L. S., Morris, J. C. & Fagan, A. M., Sep 1 2016, In: Annals of neurology. 80, 3, p. 379-387 9 p.

    Research output: Contribution to journal › Article › peer-review

    74 Scopus citations

  • Impact of structured rounding tools on time allocation during multidisciplinary rounds: An observational study

    Abraham, J., Kannampallil, T. G., Patel, V. L., Patel, B. & Almoosa, K. F., Jul 1 2016, In: JMIR Human Factors. 3, 2, e29.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    6 Scopus citations

  • Insurance status by region at the time of heart transplantation: Implications for survival

    Foraker, R. E., Tumin, D., Smith, S., Tobias, J. D. & Hayes, D., Dec 1 2016, In: Journal of Heart and Lung Transplantation. 35, 12, p. 1480-1486 7 p.

    Research output: Contribution to journal › Article › peer-review

    7 Scopus citations

  • Integrative analysis of somatic mutations and transcriptomic data to functionally stratify breast cancer patients

    Zhang, J., Abrams, Z., Parvin, J. D. & Huang, K., Aug 22 2016, In: BMC genomics. 17, 513.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • Joint frailty models for zero-inflated recurrent events in the presence of a terminal event

    Liu, L., Huang, X., Yaroshinsky, A. & Cormier, J. N., Mar 1 2016, In: Biometrics. 72, 1, p. 204-214 11 p.

    Research output: Contribution to journal › Article › peer-review

    34 Scopus citations

  • Longitudinal relationships among biomarkers for Alzheimer disease in the Adult Children Study

    Xiong, C., Jasielec, M. S., Weng, H., Fagan, A. M., Benzinger, T. L. S., Head, D., Hassenstab, J., Grant, E., Sutphen, C. L., Buckles, V., Moulder, K. L. & Morris, J. C., Apr 19 2016, In: Neurology. 86, 16, p. 1499-1506 8 p.

    Research output: Contribution to journal › Article › peer-review

    32 Scopus citations

  • MicroRNA profiling of patient plasma for clinical trials using bioinformatics and biostatistical approaches

    Markowitz, J., Abrams, Z., Jacob, N. K., Zhang, X., Hassani, J. N., Latchana, N., Wei, L., Regan, K. E., Brooks, T. R., Uppati, S. R., Levine, K. M., Bekaii-Saab, T., Kendra, K. L., Lesinski, G. B., Howard, J. H., Olencki, T., Payne, P. R. & Carson, W. E., Sep 29 2016, In: OncoTargets and Therapy. 9, p. 5931-5941 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5 Scopus citations

  • MSAcquisitionSimulator: Data-dependent acquisition simulator for LC-MS shotgun proteomics

    Goldfarb, D., Wang, W. & Major, M. B., Apr 15 2016, In: Bioinformatics. 32, 8, p. 1269-1271 3 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers

    Murakami, K., Günesdogan, U., Zylicz, J. J., Tang, W. W. C., Sengupta, R., Kobayashi, T., Kim, S., Butler, R., Dietmann, S. & Surani, M. A., Jan 21 2016, In: Nature. 529, 7586, p. 403-407 5 p.

    Research output: Contribution to journal › Article › peer-review

    131 Scopus citations

  • Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS)

    Dominantly Inherited Alzheimer Network (DIAN), Dec 1 2016, In: The Lancet Neurology. 15, 13, p. 1317-1325 9 p.

    Research output: Contribution to journal › Article › peer-review

    76 Scopus citations

  • New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

    Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, Å. K., Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S., & 239 othersLagou, V., Li, R., Li, X., Locke, A., Lu, C., Mägi, R., Perry, J. R. B., Pers, T. H., Qi, Q., Sanna, M., Schmidt, E. M., Scott, W. R., Shungin, D., Teumer, A., Vinkhuyzen, A. A. E., Walker, R. W., Westra, H. J., Zhang, M., Zhang, W., Zhao, J. H., Zhu, Z., Afzal, U., Ahluwalia, T. S., Bakker, S. J. L., Bellis, C., Bonnefond, A., Borodulin, K., Buchman, A. S., Cederholm, T., Choh, A. C., Choi, H. J., Curran, J. E., De Groot, L. C. P. G. M., De Jager, P. L., Dhonukshe-Rutten, R. A. M., Enneman, A. W., Eury, E., Evans, D. S., Forsen, T., Friedrich, N., Fumeron, F., Garcia, M. E., Gärtner, S., Han, B. G., Havulinna, A. S., Hayward, C., Hernandez, D., Hillege, H., Ittermann, T., Kent, J. W., Kolcic, I., Laatikainen, T., Lahti, J., Leach, I. M., Lee, C. G., Lee, J. Y., Liu, T., Liu, Y., Lobbens, S., Loh, M., Lyytikaïnen, L. P., Medina-Gomez, C., Michaëlsson, K., Nalls, M. A., Nielson, C. M., Oozageer, L., Pascoe, L., Paternoster, L., Polašek, O., Ripatti, S., Sarzynski, M. A., Shin, C. S., Naranäiä, N. S., Spira, D., Srikanth, P., Steinhagen-Thiessen, E., Sung, Y. J., Swart, K. M. A., Taittonen, L., Tanaka, T., Tikkanen, E., Van Der Velde, N., Van Schoor, N. M., Verweij, N., Wright, A. F., Yu, L., Zmuda, J. M., Eklund, N., Forrester, T., Grarup, N., Jackson, A. U., Kristiansson, K., Kuulasmaa, T., Kuusisto, J., Lichtner, P., Luan, J., Mahajan, A., Männistö, S., Palmer, C. D., Ried, J. S., Scott, R. A., Stancáková, A., Wagner, P. J., Demirkan, A., Döring, A., Gudnason, V., Kiel, D. P., Kühnel, B., Mangino, M., McKnight, B., Menni, C., O'Connell, J. R., Oostra, B. A., Shuldiner, A. R., Song, K., Vandenput, L., Van Duijn, C. M., Vollenweider, P., White, C. C., Boehnke, M., Boettcher, Y., Cooper, R. S., Forouhi, N. G., Gieger, C., Grallert, H., Hingorani, A., Jørgensen, T., Jousilahti, P., Kivimaki, M., Kumari, M., Laakso, M., Langenberg, C., Linneberg, A., Luke, A., McKenzie, C. A., Palotie, A., Pedersen, O., Peters, A., Strauch, K., Tayo, B. O., Wareham, N. J., Bennett, D. A., Bertram, L., Blangero, J., Blüher, M., Bouchard, C., Campbell, H., Cho, N. H., Cummings, S. R., Czerwinski, S. A., Demuth, I., Eckardt, R., Eriksson, J. G., Ferrucci, L., Franco, O. H., Froguel, P., Gansevoort, R. T., Hansen, T., Harris, T. B., Hastie, N., Heliövaara, M., Hofman, A., Jordan, J. M., Jula, A., Kähönen, M., Kajantie, E., Knekt, P. B., Koskinen, S., Kovacs, P., Lehtimäki, T., Lind, L., Liu, Y., Orwoll, E. S., Osmond, C., Perola, M., Pérusse, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Rivadeneira, F., Rudan, I., Salomaa, V., Sørensen, T. I. A., Stumvoll, M., Tönjes, A., Towne, B., Tranah, G. J., Tremblay, A., Uitterlinden, A. G., Van Der Harst, P., Vartiainen, E., Viikari, J. S., Vitart, V., Vohl, M. C., Völzke, H., Walker, M., Wallaschofski, H., Wild, S., Wilson, J. F., Yengo, L., Bishop, D. T., Borecki, I. B., Chambers, J. C., Cupples, L. A., Dehghan, A., Deloukas, P., Fatemifar, G., Fox, C., Furey, T. S., Franke, L., Han, J., Hunter, D. J., Karjalainen, J., Karpe, F., Kaplan, R. C., Kooner, J. S., McCarthy, M. I., Murabito, J. M., Morris, A. P., Bishop, J. A. N., North, K. E., Ohlsson, C., Ong, K. K., Prokopenko, I., Richards, J. B., Schadt, E. E., Spector, T. D., Widén, E., Willer, C. J., Yang, J., Ingelsson, E., Mohlke, K. L., Hirschhorn, J. N., Pospisilik, J. A., Zillikens, M. C., Lindgren, C., Kilpelaïnen, T. O. & Loos, R. J. F., Feb 1 2016, In: Nature communications. 7, 10495.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    205 Scopus citations

  • No survival benefit to gaining private health insurance coverage for post-lung transplant care in adults with cystic fibrosis

    Tumin, D., Foraker, R. E., Tobias, J. D. & Hayes, D., Mar 1 2016, In: Clinical Transplantation. 30, 3, p. 320-327 8 p.

    Research output: Contribution to journal › Article › peer-review

    7 Scopus citations

  • Particulate air pollution exposure and expression of viral and human MicroRNAs in blood: The beijing truck driver air pollution study

    Hou, L., Barupal, J., Zhang, W., Zheng, Y., Liu, L., Zhang, X., Dou, C., McCracken, J. P., Díaz, A., Motta, V., Sanchez-Guerra, M., Wolf, K. R., Bertazzi, P. A., Schwartz, J. D., Wang, S. & Baccarelli, A. A., Mar 2016, In: Environmental Health Perspectives. 124, 3, p. 344-350 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    34 Scopus citations

  • Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study

    Chatterjee, P., Lim, W. L. F., Shui, G., Gupta, V. B., James, I., Fagan, A. M., Xiong, C., Sohrabi, H. R., Taddei, K., Brown, B. M., Benzinger, T., Masters, C., Snowden, S. G., Wenk, M. R., Bateman, R. J., Morris, J. C. & Martins, R. N., Feb 2 2016, In: Journal of Alzheimer's Disease. 50, 3, p. 887-894 8 p.

    Research output: Contribution to journal › Article › peer-review

    34 Scopus citations

  • Post Hoc Analyses of ApoE Genotype-Defined Subgroups in Clinical Trials

    Kennedy, R. E., Cutter, G. R., Wang, G. & Schneider, L. S., Feb 22 2016, In: Journal of Alzheimer's Disease. 50, 4, p. 1205-1215 11 p.

    Research output: Contribution to journal › Article › peer-review

    7 Scopus citations

  • Prospective changes in global DNA methylation and cancer incidence and mortality

    Joyce, B. T., Gao, T., Zheng, Y., Liu, L., Zhang, W., Dai, Q., Shrubsole, M. J., Hibler, E. A., Cristofanilli, M., Zhang, H., Yang, H., Vokonas, P., Cantone, L., Schwartz, J., Baccarelli, A. & Hou, L., Aug 9 2016, In: British Journal of Cancer. 115, 4, p. 465-472 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    31 Scopus citations

  • Quantitative Amyloid imaging in autosomal Dominant Alzheimer's disease: Results from the DIAN study group

    Su, Y., Blazey, T. M., Owen, C. J., Christensen, J. J., Friedrichsen, K., Joseph-Mathurin, N., Wang, Q., Hornbeck, R. C., Ances, B. M., Snyder, A. Z., Cash, L. A., Koeppe, R. A., Klunk, W. E., Galasko, D., Brickman, A. M., McDade, E., Ringman, J. M., Thompson, P. M., Saykin, A. J., Ghetti, B., & 16 othersSperling, R. A., Johnson, K. A., Salloway, S. P., Schofield, P. R., Masters, C. L., Villemagne, V. L., Fox, N. C., Förster, S., Chen, K., Reiman, E. M., Xiong, C., Marcus, D. S., Weiner, M. W., Morris, J. C., Bateman, R. J. & Benzinger, T. L. S., Mar 2016, In: PloS one. 11, 3, e0152082.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    39 Scopus citations

  • Quantitative computed tomography classification of lung nodules: initial comparison of 2- and 3-dimensional analysis

    Gierada, D. S., Politte, D. G., Zheng, J., Schechtman, K. B., Whiting, B. R., Smith, K. E., Crabtree, T., Kreisel, D., Krupnick, A. S., Patterson, G. A., Puri, V. & Meyers, B. F., Jul 1 2016, In: Journal of computer assisted tomography. 40, 4, p. 589-595 7 p.

    Research output: Contribution to journal › Article › peer-review

    7 Scopus citations

  • Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans

    Olfson, E., Saccone, N. L., Johnson, E. O., Chen, L. S., Culverhouse, R., Doheny, K., Foltz, S. M., Fox, L., Gogarten, S. M., Hartz, S., Hetrick, K., Laurie, C. C., Marosy, B., Amin, N., Arnett, D., Barr, R. G., Bartz, T. M., Bertelsen, S., Borecki, I. B., Brown, M. R., & 33 othersChasman, D. I., Van Duijn, C. M., Feitosa, M. F., Fox, E. R., Franceschini, N., Franco, O. H., Grove, M. L., Guo, X., Hofman, A., Kardia, S. L. R., Morrison, A. C., Musani, S. K., Psaty, B. M., Rao, D. C., Reiner, A. P., Rice, K., Ridker, P. M., Rose, L. M., Schick, U. M., Schwander, K., Uitterlinden, A. G., Vojinovic, D., Wang, J. C., Ware, E. B., Wilson, G., Yao, J., Zhao, W., Breslau, N., Hatsukami, D., Stitzel, J. A., Rice, J., Goate, A. & Bierut, L. J., May 1 2016, In: Molecular Psychiatry. 21, 5, p. 601-607 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    28 Scopus citations

  • 'RE:fine drugs': an interactive dashboard to access drug repurposing opportunities

    Moosavinasab, S., Patterson, J., Strouse, R., Rastegar-Mojarad, M., Regan, K., Payne, P. R. O., Huang, Y. & Lin, S. M., 2016, In: Database : the journal of biological databases and curation. 2016

    Research output: Contribution to journal › Article › peer-review

    Open Access
    44 Scopus citations

  • Relationship between symptom change, relapse activity and disability progression in multiple sclerosis

    Liu, Y., Morgan, C., Hornung, L., Tyry, T., Salter, A. R., Agashivala, N., Belletti, D. A., Kim, E., Fox, R. J., Cofield, S. S. & Cutter, G. R., Mar 15 2016, In: Journal of the Neurological Sciences. 362, p. 121-126 6 p.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • Rethinking the role and impact of health information technology: Informatics as an interventional discipline

    Payne, P. R. O., Lussier, Y., Foraker, R. E. & Embi, P. J., 2016, In: BMC Medical Informatics and Decision Making. 16, 1, 40.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    13 Scopus citations

  • Risk Factors for Incident Hospitalized Heart Failure with Preserved Versus Reduced Ejection Fraction in a Multiracial Cohort of Postmenopausal Women

    Eaton, C. B., Pettinger, M., Rossouw, J., Martin, L. W., Foraker, R., Quddus, A., Liu, S., Wampler, N. S., Hank Wu, W. C., Manson, J. E., Margolis, K., Johnson, K. C., Allison, M., Corbie-Smith, G., Rosamond, W., Breathett, K. & Klein, L., Oct 1 2016, In: Circulation: Heart Failure. 9, 10, e002883.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    131 Scopus citations

  • Simultaneous paralogue knockout using a CRISPR-concatemer in mouse small intestinal organoids

    Andersson-Rolf, A., Merenda, A., Mustata, R. C., Li, T., Dietmann, S. & Koo, B. K., Dec 15 2016, In: Developmental Biology. 420, 2, p. 271-277 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    18 Scopus citations

  • Stem cell function and stress response are controlled by protein synthesis

    Blanco, S., Bandiera, R., Popis, M., Hussain, S., Lombard, P., Aleksic, J., Sajini, A., Tanna, H., Cortés-Garrido, R., Gkatza, N., Dietmann, S. & Frye, M., Jun 15 2016, In: Nature. 534, 7607, p. 335-340 6 p.

    Research output: Contribution to journal › Article › peer-review

    280 Scopus citations