Institute for Informatics, Data Science and Biostatistics (I2DB)

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  • 2016

    Blood Epigenetic Age may Predict Cancer Incidence and Mortality

    Zheng, Y., Joyce, B. T., Colicino, E., Liu, L., Zhang, W., Dai, Q., Shrubsole, M. J., Kibbe, W. A., Gao, T., Zhang, Z., Jafari, N., Vokonas, P., Schwartz, J., Baccarelli, A. A. & Hou, L., Mar 1 2016, In: EBioMedicine. 5, p. 68-73 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    163 Scopus citations

  • Cardiovascular Health and Incident Cardiovascular Disease and Cancer: The Women's Health Initiative

    Foraker, R. E., Abdel-Rasoul, M., Kuller, L. H., Jackson, R. D., Van Horn, L., Seguin, R. A., Safford, M. M., Wallace, R. B., Kucharska-Newton, A. M., Robinson, J. G., Martin, L. W., Agha, G., Hou, L., Allen, N. B. & Tindle, H. A., Feb 1 2016, In: American Journal of Preventive Medicine. 50, 2, p. 236-240 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    48 Scopus citations

  • Cell type-dependent Erk-Akt pathway crosstalk regulates the proliferation of fetal neural progenitor cells

    Rhim, J. H., Luo, X., Gao, D., Xu, X., Zhou, T., Li, F., Wang, P., Wong, S. T. C. & Xia, X., May 23 2016, In: Scientific reports. 6, 26547.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • Certified normal: Alzheimer's disease biomarkers and normative estimates of cognitive functioning

    Hassenstab, J., Chasse, R., Grabow, P., Benzinger, T. L. S., Fagan, A. M., Xiong, C., Jasielec, M., Grant, E. & Morris, J. C., Jul 1 2016, In: Neurobiology of Aging. 43, p. 23-33 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    47 Scopus citations

  • Characterizing the pain score trajectories of hospitalized adult medical and surgical patients: A retrospective cohort study

    Kannampallil, T., Galanter, W. L., Falck, S., Gaunt, M. J., Gibbons, R. D., McNutt, R., Odwazny, R., Schiff, G., Vaida, A. J., Wilkie, D. J. & Lambert, B. L., Aug 10 2016, In: Pain. 157, 12, p. 2739-2746 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    33 Scopus citations

  • Characterizing the structure and content of nurse handoffs: A Sequential Conversational Analysis approach

    Abraham, J., Kannampallil, T., Brenner, C., Lopez, K. D., Almoosa, K. F., Patel, B. & Patel, V. L., Feb 1 2016, In: Journal of Biomedical Informatics. 59, p. 76-88 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    36 Scopus citations

  • Clinical trial readiness in non-ambulatory boys and men with duchenne muscular dystrophy: MDA–DMD network follow-up

    the MDA–DMD Clinical Research Network, Oct 1 2016, In: Muscle and Nerve. 54, 4, p. 681-689 9 p.

    Research output: Contribution to journal › Article › peer-review

    31 Scopus citations

  • Clinicopathologic characteristics and survival of patients with gynecologic malignancies metastatic to the brain

    Divine, L. M., Kizer, N. T., Hagemann, A. R., Pittman, M. E., Chen, L., Powell, M. A., Mutch, D. G., Rader, J. S. & Thaker, P. H., Jul 1 2016, In: Gynecologic oncology. 142, 1, p. 76-82 7 p.

    Research output: Contribution to journal › Article › peer-review

    27 Scopus citations

  • Common variants in the Na +-coupled bicarbonate transporter genes and salt sensitivity of blood pressure: The GenSalt study

    Guo, L., Liu, F., Chen, S., Yang, X., Huang, J., He, J., Jaquish, C. E., Zhao, Q., Gu, C. C., Hixson, J. E. & Gu, D., Sep 1 2016, In: Journal of Human Hypertension. 30, 9, p. 543-548 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • Comparison of risk scores for the prediction of stroke in African Americans: Findings from the Jackson Heart Study

    Foraker, R. E., Greiner, M., Sims, M., Tucker, K. L., Towfighi, A., Bidulescu, A., Shoben, A. B., Smith, S., Talegawkar, S., Blackshear, C., Wang, W., Hardy, N. C. & O'Brien, E., Jul 1 2016, In: American heart journal. 177, p. 25-32 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

    Allen, G. I., Amoroso, N., Anghel, C., Balagurusamy, V., Bare, C. J., Beaton, D., Bellotti, R., Bennett, D. A., Boehme, K. L., Boutros, P. C., Caberlotto, L., Caloian, C., Campbell, F., Chaibub Neto, E., Chang, Y. C., Chen, B., Chen, C. Y., Chien, T. Y., Clark, T. & Das, S. & 81 others, Davatzikos, C., Deng, J., Dillenberger, D., Dobson, R. J. B., Dong, Q., Doshi, J., Duma, D., Errico, R., Erus, G., Everett, E., Fardo, D. W., Friend, S. H., Fröhlich, H., Gan, J., St George-Hyslop, P., Ghosh, S. S., Glaab, E., Green, R. C., Guan, Y., Hong, M. Y., Huang, C., Hwang, J., Ibrahim, J., Inglese, P., Iyappan, A., Jiang, Q., Katsumata, Y., Kauwe, J. S. K., Klein, A., Kong, D., Krause, R., Lalonde, E., Lauria, M., Lee, E., Lin, X., Liu, Z., Livingstone, J., Logsdon, B. A., Lovestone, S., Ma, T. W., Malhotra, A., Mangravite, L. M., Maxwell, T. J., Merrill, E., Nagorski, J., Namasivayam, A., Narayan, M., Naz, M., Newhouse, S. J., Norman, T. C., Nurtdinov, R. N., Oyang, Y. J., Pawitan, Y., Peng, S., Peters, M. A., Piccolo, S. R., Praveen, P., Priami, C., Sabelnykova, V. Y., Senger, P., Shen, X., Simmons, A., Sotiras, A., Stolovitzky, G., Tangaro, S., Tateo, A., Tung, Y. A., Tustison, N. J., Varol, E., Vradenburg, G., Weiner, M. W., Xiao, G., Xie, L., Xie, Y., Xu, J., Yang, H., Zhan, X., Zhou, Y., Zhu, F., Zhu, H. & Zhu, S., Jun 1 2016, In: Alzheimer's and Dementia. 12, 6, p. 645-653 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    63 Scopus citations

  • Decreasing food fussiness in children with obesity leads to greater weight loss in family-based treatment

    Hayes, J. F., Altman, M., Kolko, R. P., Balantekin, K. N., Holland, J. C., Stein, R. I., Saelens, B. E., Welch, R. R., Perri, M. G., Schechtman, K. B., Epstein, L. H. & Wilfley, D. E., Oct 1 2016, In: Obesity. 24, 10, p. 2158-2163 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Scopus citations

  • Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient carrying mutations in NSUN3

    Van Haute, L., Dietmann, S., Kremer, L., Hussain, S., Pearce, S. F., Powell, C. A., Rorbach, J., Lantaff, R., Blanco, S., Sauer, S., Kotzaeridou, U., Hoffmann, G. F., Memari, Y., Kolb-Kokocinski, A., Durbin, R., Mayr, J. A., Frye, M., Prokisch, H. & Minczuk, M., Jun 30 2016, In: Nature communications. 7, 12039.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    191 Scopus citations

  • Designing a Clinical Data Warehouse Architecture to Support Quality Improvement Initiatives

    Chelico, J. D., Wilcox, A. B., Vawdrey, D. K. & Kuperman, G. J., 2016, In: AMIA ... Annual Symposium proceedings. AMIA Symposium. 2016, p. 381-390 10 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations

  • Detecting Dysglycemia Using the 2015 United States Preventive Services Task Force Screening Criteria: A Cohort Analysis of Community Health Center Patients

    O’Brien, M. J., Lee, J. Y., Carnethon, M. R., Ackermann, R. T., Vargas, M. C., Hamilton, A., Mohanty, N., Rittner, S. S., Park, J. N., Hassan, A., Buchanan, D. R., Liu, L. & Feinglass, J., Jul 2016, In: PLoS medicine. 13, 7, e1002074.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    27 Scopus citations

  • Development of a model to predict breast cancer survival using data from the National Cancer Data Base

    Asare, E. A., Liu, L., Hess, K. R., Gordon, E. J., Paruch, J. L., Palis, B., Dahlke, A. R., McCabe, R., Cohen, M. E., Winchester, D. P. & Bilimoria, K. Y., Feb 1 2016, In: Surgery (United States). 159, 2, p. 495-502 8 p.

    Research output: Contribution to journal › Article › peer-review

    9 Scopus citations

  • Development of a tethered personal health record framework for early End-of-Life Discussions

    Bose-Brill, S., Kretovics, M., Ballenger, T., Modan, G., Lai, A., Belanger, L., Koesters, S., Pressler-Vydra, T. & Wills, C., Jun 2016, In: American Journal of Managed Care. 22, 6, p. 412-418 7 p.

    Research output: Contribution to journal › Article › peer-review

    7 Scopus citations

  • Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology

    Abner, E. L., Nelson, P. T., Kryscio, R. J., Schmitt, F. A., Fardo, D. W., Woltjer, R. L., Cairns, N. J., Yu, L., Dodge, H. H., Xiong, C., Masaki, K., Tyas, S. L., Bennett, D. A., Schneider, J. A. & Arvanitakis, Z., Aug 1 2016, In: Alzheimer's and Dementia. 12, 8, p. 882-889 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    185 Scopus citations

  • Differential risks for adverse outcomes 3 years after kidney transplantation based on initial immunosuppression regimen: a national study

    Dharnidharka, V. R., Schnitzler, M. A., Chen, J., Brennan, D. C., Axelrod, D., Segev, D. L., Schechtman, K. B., Zheng, J. & Lentine, K. L., Nov 1 2016, In: Transplant International. 29, 11, p. 1226-1236 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    44 Scopus citations

  • Different Vancomycin Immunoassays Contribute to the Variability in Vancomycin Trough Measurements in Neonates

    Samardzic, J., Smits, A., Spriet, I., Soldatovic, I., Atkinson, A., Bajcetic, M., Van Den Anker, J. N. & Allegaert, K., 2016, In: BioMed Research International. 2016, 1974972.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations

  • Disability progression after switching from natalizumab to fingolimod or interferon beta/glatiramer acetate therapies: A NARCOMS analysis

    Cofield, S. S., Fox, R. J., Tyry, T., Salter, A. R. & Campagnolo, D., 2016, In: International Journal of MS Care. 18, 5, p. 230-238 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    4 Scopus citations

  • DNA methylation of oxidative stress genes and cancer risk in the Normative Aging Study

    Gao, T., Joyce, B. T., Liu, L., Zheng, Y., Dai, Q., Zhang, Z., Zhang, W., Shrubsole, M. J., Tao, M. H., Schwartz, J., Baccarelli, A. & Hou, L., 2016, In: American Journal of Cancer Research. 6, 2, p. 553-561 9 p.

    Research output: Contribution to journal › Article › peer-review

    18 Scopus citations

  • Drug repurposing hypothesis generation using the "RE:fine drugs" system

    Regan, K., Moosavinasab, S., Payne, P. & Lin, S., Dec 11 2016, In: Journal of Visualized Experiments. 2016, 118, e54948.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    4 Scopus citations

  • Efficacy and safety of deflazacort vs prednisone and placebo for Duchenne muscular dystrophy

    Griggs, R. C., Miller, J. P., Greenberg, C. R., Fehlings, D. L., Pestronk, A., Mendell, J. R., Moxley, R. T., King, W., Kissel, J. T., Cwik, V., Vanasse, M., Florence, J. M., Pandya, S., Dubow, J. S. & Meyer, J. M., Nov 15 2016, In: Neurology. 87, 20, p. 2123-2131 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    138 Scopus citations

  • Electronic health record-based assessment of cardiovascular health: The stroke prevention in healthcare delivery environments (SPHERE) study

    Foraker, R. E., Shoben, A. B., Kelley, M. M., Lai, A. M., Lopetegui, M. A., Jackson, R. D., Langan, M. A. & Payne, P. R. O., Dec 1 2016, In: Preventive Medicine Reports. 4, p. 303-308 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    19 Scopus citations

  • Environmental Enteric Dysfunction Includes a Broad Spectrum of Inflammatory Responses and Epithelial Repair Processes

    Yu, J., Ordiz, M. I., Stauber, J., Shaikh, N., Trehan, I., Barnell, E., Head, R. D., Maleta, K., Tarr, P. I. & Manary, M. J., Feb 1 2016, In: CMGH. 2, 2, p. 158-174.e1

    Research output: Contribution to journal › Article › peer-review

    Open Access
    54 Scopus citations

  • Examining the joint effect of disability, health behaviors, and comorbidity on mortality in MS

    Salter, A., Tyry, T., Wang, G., Fox, R. J., Cutter, G. & Marrie, R. A., Oct 1 2016, In: Neurology: Clinical Practice. 6, 5, p. 397-408 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    22 Scopus citations

  • Exploring the feasibility and acceptability of sensor monitoring of gait and falls in the homes of persons with multiple sclerosis

    Newland, P., Wagner, J. M., Salter, A., Thomas, F. P., Skubic, M. & Rantz, M., Sep 1 2016, In: Gait and Posture. 49, p. 277-282 6 p.

    Research output: Contribution to journal › Article › peer-review

    14 Scopus citations

  • Expression of TIA1 and PAX5 in Classical Hodgkin Lymphoma at Initial Diagnosis May Predict Clinical Outcome

    Nguyen, T. D. T., Frater, J. L., Klein, J., Chen, L., Bartlett, N. L., Foyil, K. V. & Kreisel, F. H., Jul 1 2016, In: Applied Immunohistochemistry and Molecular Morphology. 24, 6, p. 383-391 9 p.

    Research output: Contribution to journal › Article › peer-review

    11 Scopus citations

  • Folate-conjugated immunoglobulin targets melanoma tumor cells for NK cell effector functions

    Skinner, C. C., McMichael, E. L., Jaime-Ramirez, A. C., Abrams, Z. B., Lee, R. J. & Carson, W. E., Aug 1 2016, In: Melanoma Research. 26, 4, p. 329-337 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations

  • Genetic association of left ventricular mass assessed by M-mode and two-dimensional echocardiography

    Barve, R. A., Gu, C. C., Yang, W., Chu, J., Dávila-Román, V. G. & De Las Fuentes, L., Jan 1 2016, In: Journal of Hypertension. 34, 1, p. 88-96 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5 Scopus citations

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Pattaro, C., Teumer, A., Gorski, M., Chu, A. Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M. H., Pers, T. H., Johnson, A. D., Ko, Y. A., Fuchsberger, C. & Tayo, B. & 678 others, Nalls, M., Feitosa, M. F., Isaacs, A., Dehghan, A., D'Adamo, P., Adeyemo, A., Dieffenbach, A. K., Zonderman, A. B., Nolte, I. M., Van Der Most, P. J., Wright, A. F., Shuldiner, A. R., Morrison, A. C., Hofman, A., Smith, A. V., Dreisbach, A. W., Franke, A., Uitterlinden, A. G., Metspalu, A., Tonjes, A., Lupo, A., Robino, A., Johansson, Å., Demirkan, A., Kollerits, B., Freedman, B. I., Ponte, B., Oostra, B. A., Paulweber, B., Krämer, B. K., Mitchell, B. D., Buckley, B. M., Peralta, C. A., Hayward, C., Helmer, C., Rotimi, C. N., Shaffer, C. M., Müller, C., Sala, C., Van Duijn, C. M., Saint-Pierre, A., Ackermann, D., Shriner, D., Ruggiero, D., Toniolo, D., Lu, Y., Cusi, D., Czamara, D., Ellinghaus, D., Siscovick, D. S., Ruderfer, D., Gieger, C., Grallert, H., Rochtchina, E., Atkinson, E. J., Holliday, E. G., Boerwinkle, E., Salvi, E., Bottinger, E. P., Murgia, F., Rivadeneira, F., Ernst, F., Kronenberg, F., Hu, F. B., Navis, G. J., Curhan, G. C., Ehret, G. B., Homuth, G., Coassin, S., Thun, G. A., Pistis, G., Gambaro, G., Malerba, G., Montgomery, G. W., Eiriksdottir, G., Jacobs, G., Li, G., Wichmann, H. E., Campbell, H., Schmidt, H., Wallaschofski, H., Völzke, H., Brenner, H., Kroemer, H. K., Kramer, H., Lin, H., Leach, I. M., Ford, I., Guessous, I., Rudan, I., Prokopenko, I., Borecki, I., Heid, I. M., Kolcic, I., Persico, I., Jukema, J. W., Wilson, J. F., Felix, J. F., Divers, J., Lambert, J. C., Stafford, J. M., Gaspoz, J. M., Smith, J. A., Faul, J. D., Wang, J. J., Ding, J., Hirschhorn, J. N., Attia, J., Whitfield, J. B., Chalmers, J., Viikari, J., Coresh, J., Denny, J. C., Karjalainen, J., Fernandes, J. K., Endlich, K., Butterbach, K., Keene, K. L., Lohman, K., Portas, L., Launer, L. J., Lyytikäinen, L. P., Yengo, L., Franke, L., Ferrucci, L., Rose, L. M., Kedenko, L., Rao, M., Struchalin, M., Kleber, M. E., Cavalieri, M., Haun, M., Cornelis, M. C., Ciullo, M., Pirastu, M., De Andrade, M., McEvoy, M. A., Woodward, M., Adam, M., Cocca, M., Nauck, M., Imboden, M., Waldenberger, M., Pruijm, M., Metzger, M., Stumvoll, M., Evans, M. K., Sale, M. M., Kähönen, M., Boban, M., Bochud, M., Rheinberger, M., Verweij, N., Bouatia-Naji, N., Martin, N. G., Hastie, N., Probst-Hensch, N., Soranzo, N., Devuyst, O., Raitakari, O., Gottesman, O., Franco, O. H., Polasek, O., Gasparini, P., Munroe, P. B., Ridker, P. M., Mitchell, P., Muntner, P., Meisinger, C., Smit, J. H., Abecasis, G. R., Adair, L. S., Alexander, M., Altshuler, D., Amin, N., Arking, D. E., Arora, P., Aulchenko, Y., Bakker, S. J. L., Bandinelli, S., Barroso, I., Beckmann, J. S., Beilby, J. P., Bergman, R. N., Bergmann, S., Bis, J. C., Boehnke, M., Bonnycastle, L. L., Bornstein, S. R., Bots, M. L., Bragg-Gresham, J. L., Brand, S. M., Brand, E., Braund, P. S., Brown, M. J., Burton, P. R., Casas, J. P., Caulfield, M. J., Chakravarti, A., Chambers, J. C., Chandak, G. R., Chang, Y. P. C., Charchar, F. J., Chaturvedi, N., Cho, Y. S., Clarke, R., Collins, F. S., Collins, R., Connell, J. M., Cooper, J. A., Cooper, M. N., Cooper, R. S., Corsi, A. M., Dörr, M., Dahgam, S., Danesh, J., Smith, G. D., Day, I. N. M., Deloukas, P., Denniff, M., Dominiczak, A. F., Dong, Y., Doumatey, A., Elliott, P., Elosua, R., Erdmann, J., Eyheramendy, S., Farrall, M., Fava, C., Forrester, T., Fowkes, F. G. R., Fox, E. R., Frayling, T. M., Galan, P., Ganesh, S. K., Garcia, M., Gaunt, T. R., Glazer, N. L., Go, M. J., Goel, A., Grässler, J., Grobbee, D. E., Groop, L., Guarrera, S., Guo, X., Hadley, D., Hamsten, A., Han, B. G., Hardy, R., Hartikainen, A. L., Heath, S., Heckbert, S. R., Hedblad, B., Hercberg, S., Hernandez, D., Hicks, A. A., Hilton, G., Hingorani, A. D., Hoffman Bolton, J. A., Hopewell, J. C., Howard, P., Humphries, S. E., Hunt, S. C., Hveem, K., Ikram, M. A., Islam, M., Iwai, N., Jarvelin, M. R., Jackson, A. U., Jafar, T. H., Janipalli, C. S., Johnson, T., Kathiresan, S., Khaw, K. T., Kim, H. L., Kinra, S., Kita, Y., Kivimaki, M., Kooner, J. S., Kumar, M. J. K., Kuh, D., Kulkarni, S. R., Kumari, M., Kuusisto, J., Kuznetsova, T., Laakso, M., Laan, M., Laitinen, J., Lakatta, E. G., Langefeld, C. D., Larson, M. G., Lathrop, M., Lawlor, D. A., Lawrence, R. W., Lee, J. Y., Lee, N. R., Levy, D., Li, Y., Longstreth, W. T., Luan, J., Lucas, G., Ludwig, B., Mangino, M., Mani, K. R., Marmot, M. G., Mattace-Raso, F. U. S., Matullo, G., McArdle, W. L., McKenzie, C. A., Meitinger, T., Melander, O., Meneton, P., Meschia, J. F., Miki, T., Milaneschi, Y., Mohlke, K. L., Mooser, V., Morken, M. A., Morris, R. W., Mosley, T. H., Najjar, S., Narisu, N., Newton-Cheh, C., Nguyen, K. D. H., Nilsson, P., Nyberg, F., O'Donnell, C. J., Ogihara, T., Ohkubo, T., Okamura, T., Ong, R. T. H., Ongen, H., Onland-Moret, N. C., O'Reilly, P. F., Org, E., Orru, M., Palmas, W., Palmen, J., Palmer, L. J., Palmer, N. D., Parker, A. N., Peden, J. F., Peltonen, L., Perola, M., Pihur, V., Platou, C. G. P., Plump, A., Prabhakaran, D., Psaty, B. M., Raffel, L. J., Rao, D. C., Rasheed, A., Ricceri, F., Rice, K. M., Rosengren, A., Rotter, J. I., Rudock, M. E., Sõber, S., Salako, T., Saleheen, D., Salomaa, V., Samani, N. J., Schwartz, S. M., Schwarz, P. E. H., Scott, L. J., Scott, J., Scuteri, A., Sehmi, J. S., Seielstad, M., Seshadri, S., Sharma, P., Shaw-Hawkins, S., Shi, G., Shrine, N. R. G., Sijbrands, E. J. G., Sim, X., Singleton, A., Sjögren, M., Smith, N. L., Artigas, M. S., Spector, T. D., Staessen, J. A., Stancakova, A., Steinle, N. I., Strachan, D. P., Stringham, H. M., Sun, Y. V., Swift, A. J., Tabara, Y., Tai, E. S., Talmud, P. J., Taylor, A., Terzic, J., Thelle, D. S., Tobin, M. D., Tomaszewski, M., Tripathy, V., Tuomilehto, J., Tzoulaki, I., Uda, M., Ueshima, H., Uiterwaal, C. S. P. M., Umemura, S., Van Der Harst, P., Van Der Schouw, Y. T., Van Gilst, W. H., Vartiainen, E., Vasan, R. S., Veldre, G., Verwoert, G. C., Viigimaa, M., Vinay, D. G., Vineis, P., Voight, B. F., Vollenweider, P., Wagenknecht, L. E., Wain, L. V., Wang, X., Wang, T. J., Wareham, N. J., Watkins, H., Weder, A. B., Whincup, P. H., Wiggins, K. L., Witteman, J. C. M., Wong, A., Wu, Y., Yajnik, C. S., Yao, J., Young, J. H., Zelenika, D., Zhai, G., Zhang, W., Zhang, F., Zhao, J. H., Zhu, H., Zhu, X., Zitting, P., Zukowska-Szczechowska, E., Okada, Y., Wu, J. Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S. C., Wong, T. Y., Liu, J., Young, T. L., Aung, T., Teo, Y. Y., Kim, Y. J., Kang, D., Chen, C. H., Tsai, F. J., Chang, L. C., Fann, S. J. C., Mei, H., Hixson, J. 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B., Watzinger, N., Aragam, J., Zweiker, R., Lind, L., Rodeheffer, R. J., Greiser, K. H., Deckers, J. W., Stritzke, J., Ingelsson, E., Kullo, I., Haerting, J., Reffelmann, T., Redfield, M. M., Werdan, K., Mitchell, G. F., Arnett, D. K., Gottdiener, J. S., Blettner, M., Friedrich, N., Kovacs, P., Wild, P. S., Froguel, P., Rettig, R., Mägi, R., Biffar, R., Schmidt, R., Middelberg, R. P. S., Carroll, R. J., Penninx, B. W., Scott, R. J., Katz, R., Sedaghat, S., Wild, S. H., Kardia, S. L. R., Ulivi, S., Hwang, S. J., Enroth, S., Kloiber, S., Trompet, S., Stengel, B., Hancock, S. J., Turner, S. T., Rosas, S. E., Stracke, S., Harris, T. B., Zeller, T., Zemunik, T., Lehtimäki, T., Illig, T., Aspelund, T., Nikopensius, T., Esko, T., Tanaka, T., Gyllensten, U., Völker, U., Emilsson, V., Vitart, V., Aalto, V., Gudnason, V., Chouraki, V., Chen, W. M., Igl, W., März, W., Koenig, W., Lieb, W., Loos, R. J. F., Liu, Y., Snieder, H., Pramstaller, P. P., Parsa, A., O'Connell, J. R., Susztak, K., Hamet, P., Tremblay, J., De Boer, I. H., Böger, C. A., Goessling, W., Chasman, D. I., Köttgen, A., Kao, W. H. L. & Fox, C. S., Jan 21 2016, In: Nature communications. 7, 10023.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    402 Scopus citations

  • Genetics and population analysis: Estimating and testing high-dimensional mediation effects in epigenetic studies

    Zhang, H., Zheng, Y., Zhang, Z., Gao, T., Joyce, B., Yoon, G., Zhang, W., Schwartz, J., Just, A., Colicino, E., Vokonas, P., Zhao, L., Lv, J., Baccarelli, A., Hou, L. & Liu, L., Oct 15 2016, In: Bioinformatics. 32, 20, p. 3150-3154 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    116 Scopus citations

  • Genetic Susceptibility to Lipid Levels and Lipid Change over Time and Risk of Incident Hyperlipidemia in Chinese Populations

    Lu, X., Huang, J., Mo, Z., He, J., Wang, L., Yang, X., Tan, A., Chen, S., Chen, J., Charles Gu, C., Chen, J., Li, Y., Zhao, L., Li, H., Hao, Y., Li, J., Hixson, J. E., Li, Y., Cheng, M. & Liu, X. & 18 others, Cao, J., Liu, F., Huang, C., Shen, C., Shen, J., Yu, L., Xu, L., Mu, J., Wu, X., Ji, X., Guo, D., Zhou, Z., Yang, Z., Wang, R., Yang, J., Yan, W., Peng, X. & Gu, D., Feb 1 2016, In: Circulation: Cardiovascular Genetics. 9, 1, p. 37-44 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    52 Scopus citations

  • Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference

    Wen, W., Kato, N., Hwang, J. Y., Guo, X., Tabara, Y., Li, H., Dorajoo, R., Yang, X., Tsai, F. J., Li, S., Wu, Y., Wu, T., Kim, S., Guo, X., Liang, J., Shungin, D., Adair, L. S., Akiyama, K., Allison, M. & Cai, Q. & 56 others, Chang, L. C., Chen, C. H., Chen, Y. T., Cho, Y. S., Choi, B. Y., Gao, Y., Go, M. J., Gu, D., Han, B. G., He, M., Hixson, J. E., Hu, Y., Huang, T., Isono, M., Jung, K. J., Kang, D., Kim, Y. J., Kita, Y., Lee, J., Lee, N. R., Lee, J., Wang, Y., Liu, J. J., Long, J., Moon, S., Nakamura, Y., Nakatochi, M., Ohnaka, K., Rao, D., Shi, J., Sull, J. W., Tan, A., Ueshima, H., Wu, C., Xiang, Y. B., Yamamoto, K., Yao, J., Ye, X., Yokota, M., Zhang, X., Zheng, Y., Qi, L., Rotter, J. I., Jee, S. H., Lin, D., Mohlke, K. L., He, J., Mo, Z., Wu, J. Y., Tai, E. S., Lin, X., Miki, T., Kim, B. J., Takeuchi, F., Zheng, W. & Shu, X. O., Jan 20 2016, In: Scientific reports. 6, 17958.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    55 Scopus citations

  • Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat

    Sung, Y. J., Pérusse, L., Sarzynski, M. A., Fornage, M., Sidney, S., Sternfeld, B., Rice, T., Terry, J. G., Jacobs, D. R., Katzmarzyk, P., Curran, J. E., Jeffrey Carr, J., Blangero, J., Ghosh, S., Després, J. P., Rankinen, T., Rao, D. C. & Bouchard, C., Apr 1 2016, In: International Journal of Obesity. 40, 4, p. 662-674 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    76 Scopus citations

  • Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study

    Li, C., He, J., Chen, J., Zhao, J., Gu, D., Hixson, J. E., Rao, D. C., Jaquish, C. E., Gu, C. C., Chen, J., Huang, J., Chen, S. & Kelly, T. N., Aug 1 2016, In: Hypertension. 68, 2, p. 348-355 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    46 Scopus citations

  • Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

    Kilpeläinen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, Å. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L. P. & Eriksson, J. & 157 others, Henneman, P., Lahti, J., Tanaka, T., Luan, J., Fabiola Del, G. M., Pasko, D., Renström, F., Willems, S. M., Mahajan, A., Rose, L. M., Guo, X., Liu, Y., Kleber, M. E., Pérusse, L., Gaunt, T., Ahluwalia, T. S., Ju Sung, Y., Ramos, Y. F., Amin, N., Amuzu, A., Barroso, I., Bellis, C., Blangero, J., Buckley, B. M., Böhringer, S., I Chen, Y. D., De Craen, A. J. N., Crosslin, D. R., Dale, C. E., Dastani, Z., Day, F. R., Deelen, J., Delgado, G. E., Demirkan, A., Finucane, F. M., Ford, I., Garcia, M. E., Gieger, C., Gustafsson, S., Hallmans, G., Hankinson, S. E., Havulinna, A. S., Herder, C., Hernandez, D., Hicks, A. A., Hunter, D. J., Illig, T., Ingelsson, E., Ioan-Facsinay, A., Jansson, J. O., Jenny, N. S., Jørgensen, M. E., Jørgensen, T., Karlsson, M., Koenig, W., Kraft, P., Kwekkeboom, J., Laatikainen, T., Ladwig, K. H., Leduc, C. A., Lowe, G., Lu, Y., Marques-Vidal, P., Meisinger, C., Menni, C., Morris, A. P., Myers, R. H., Männistö, S., Nalls, M. A., Paternoster, L., Peters, A., Pradhan, A. D., Rankinen, T., Rasmussen-Torvik, L. J., Rathmann, W., Rice, T. K., Brent Richards, J., Ridker, P. M., Sattar, N., Savage, D. B., Söderberg, S., Timpson, N. J., Vandenput, L., Van Heemst, D., Uh, H. W., Vohl, M. C., Walker, M., Wichmann, H. E., Widén, E., Wood, A. R., Yao, J., Zeller, T., Zhang, Y., Meulenbelt, I., Kloppenburg, M., Astrup, A., Sørensen, T. I. A., Sarzynski, M. A., Rao, D. C., Jousilahti, P., Vartiainen, E., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Kajantie, E., Osmond, C., Palotie, A., Eriksson, J. G., Heliövaara, M., Knekt, P. B., Koskinen, S., Jula, A., Perola, M., Huupponen, R. K., Viikari, J. S., Kähönen, M., Lehtimäki, T., Raitakari, O. T., Mellström, D., Lorentzon, M., Casas, J. P., Bandinelli, S., März, W., Isaacs, A., Van Dijk, K. W., Van Duijn, C. M., Harris, T. B., Bouchard, C., Allison, M. A., Chasman, D. I., Ohlsson, C., Lind, L., Scott, R. A., Langenberg, C., Wareham, N. J., Ferrucci, L., Frayling, T. M., Pramstaller, P. P., Borecki, I. B., Waterworth, D. M., Bergmann, S., Waeber, G., Vollenweider, P., Vestergaard, H., Hansen, T., Pedersen, O., Hu, F. B., Eline Slagboom, P., Grallert, H., Spector, T. D., Jukema, J. W., Klein, R. J., Schadt, E. E., Franks, P. W., Lindgren, C. M., Leibel, R. L. & Loos, R. J. F., Feb 1 2016, In: Nature communications. 7, 10494.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    145 Scopus citations

  • Global microRNA profiling for diagnostic appraisal of melanocytic Spitz tumors

    Latchana, N., Regan, K., Howard, J. H., Aldrink, J. H., Ranalli, M. A., Peters, S. B., Zhang, X., Gru, A., Payne, P. R. O., Suarez-Kelly, L. P. & Carson, W. E., Oct 1 2016, In: Journal of Surgical Research. 205, 2, p. 350-358 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    19 Scopus citations

  • Handrub Consumption Mirrors Hand Hygiene Compliance

    Haubitz, S., Atkinson, A., Kaspar, T., Nydegger, D., Eichenberger, A., Sommerstein, R. & Marschall, J., Jun 1 2016, In: Infection Control and Hospital Epidemiology. 37, 6, p. 707-710 4 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • Health insurance affects the use of disease-modifying therapy in multiple sclerosis

    Wang, G., Marrie, R. A., Salter, A. R., Fox, R., Cofield, S. S., Tyry, T. & Cutter, G. R., Jul 26 2016, In: Neurology. 87, 4, p. 365-374 10 p.

    Research output: Contribution to journal › Article › peer-review

    35 Scopus citations

  • Health insurance trajectories and long-term survival after heart transplantation

    Tumin, D., Foraker, R. E., Smith, S., Tobias, J. D. & Hayes, D., Sep 1 2016, In: Circulation: Cardiovascular Quality and Outcomes. 9, 5, p. 576-584 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    32 Scopus citations

  • Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

    Harrison, J. S., Cornett, E. M., Goldfarb, D., Darosa, P. A., Li, Z. M., Yan, F., Dickson, B. M., Guo, A. H., Cantu, D. V., Kaustov, L., Brown, P. J., Arrowsmith, C. H., Erie, D. A., Major, M. B., Klevit, R. E., Krajewski, K., Kuhlman, B., Strahl, B. D. & Rothbart, S. B., Sep 6 2016, In: eLife. 5, Se, e17101.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    106 Scopus citations

  • High-fidelity analysis of perioperative QTc prolongation

    Duma, A., Pal, S., Helsten, D., Stein, P. K., Miller, J. P. & Nagele, P., Feb 1 2016, In: Anesthesia and analgesia. 122, 2, p. 439-448 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    14 Scopus citations

  • Human epithelial NA+ channel missense variants identified in the GenSalt study alter channel activity

    Ray, E. C., Chen, J., Kelly, T. N., He, J., Hamm, L. L., Gu, D., Shimmin, L. C., Hixson, J. E., Rao, D. C., Sheng, S. & Kleyman, T. R., 2016, In: American Journal of Physiology - Renal Physiology. 311, 5, p. F908-F914

    Research output: Contribution to journal › Article › peer-review

    Open Access
    20 Scopus citations

  • Identification and characterization of MCM3 as a kelch-like ECH-associated protein 1 (KEAP1) substrate

    Mulvaney, K. M., Matson, J. P., Siesser, P. F., Tamir, T. Y., Goldfarb, D., Jacobs, T. M., Cloer, E. W., Harrison, J. S., Vaziri, C., Cook, J. G. & Major, M. B., Nov 4 2016, In: Journal of Biological Chemistry. 291, 45, p. 23719-23733 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    70 Scopus citations

  • Imaging and cerebrospinal fluid biomarkers in early preclinical alzheimer disease

    Vlassenko, A. G., McCue, L., Jasielec, M. S., Su, Y., Gordon, B. A., Xiong, C., Holtzman, D. M., Benzinger, T. L. S., Morris, J. C. & Fagan, A. M., Sep 1 2016, In: Annals of neurology. 80, 3, p. 379-387 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    83 Scopus citations

  • Impact of structured rounding tools on time allocation during multidisciplinary rounds: An observational study

    Abraham, J., Kannampallil, T. G., Patel, V. L., Patel, B. & Almoosa, K. F., Jul 1 2016, In: JMIR Human Factors. 3, 2, e29.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • Insurance status by region at the time of heart transplantation: Implications for survival

    Foraker, R. E., Tumin, D., Smith, S., Tobias, J. D. & Hayes, D., Dec 1 2016, In: Journal of Heart and Lung Transplantation. 35, 12, p. 1480-1486 7 p.

    Research output: Contribution to journal › Article › peer-review

    7 Scopus citations

  • Integrative analysis of somatic mutations and transcriptomic data to functionally stratify breast cancer patients

    Zhang, J., Abrams, Z., Parvin, J. D. & Huang, K., Aug 22 2016, In: BMC genomics. 17, 513.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations