Institute for Informatics, Data Science and Biostatistics

Research output

Research output per year 1968 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 2584 Article
• 105 Conference contribution
• 96 Review article
• 49 Comment/debate
• 126 More
  • 43 Chapter
  • 36 Letter
  • 24 Editorial
  • 14 Conference article
  • 4 Foreword/postscript
  • 4 Paper
  • 1 Book

Research output per year

Research output per year

Search results

• 2022

  A Review of High-Dimensional Mediation Analyses in DNA Methylation Studies

  Zhang, H., Hou, L. & Liu, L., 2022, Methods in Molecular Biology. Humana Press Inc., p. 123-135 13 p. (Methods in Molecular Biology; vol. 2432).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • DNA Methylation 100%
  • Epigenomics 58%
  • Epigenome 42%
  • Methylation 30%
  • Genes 13%
  1 Scopus citations

• From data to knowledge: an introduction to biomedical informatics

  Payne, P. R. O., Jan 1 2022, Genomic and Precision Medicine: Oncology, Third Edition. Elsevier, p. 13-28 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Informatics 100%
  • Population Health 42%
  • Health Promotion 38%
  • Application 24%
  • Delivery of Health Care 24%
• 2021

  Synergistic drug combination prediction by integrating multiomics data in deep learning models

  Zhang, T., Zhang, L., Payne, P. R. O. & Li, F., 2021, Methods in Molecular Biology. Humana Press Inc., p. 223-238 16 p. (Methods in Molecular Biology; vol. 2194).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Deep Learning 100%
  • Drug Combinations 75%
  • Gene Dosage 28%
  • Neoplasms 23%
  • Drug Resistance 22%
  27 Scopus citations
• 2017

  Ethical issues in dissemination and implementation research

  Dubois, J. M. & Prusaczyk, B., Jan 1 2017, Dissemination and Implementation Research in Health: Translating Science to Practice, Second Edition. Oxford University Press, p. 63-72 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Ethics 100%
  • Formal Social Control 49%
  • Research Personnel 34%
  • Uncertainty 22%
  • Decision Making 20%
  3 Scopus citations

• From Data to Knowledge: An Introduction to Biomedical Informatics

  Payne, P. R. O., Jan 1 2017, Genomic and Precision Medicine: Foundations, Translation, and Implementation: Third Edition. Elsevier Inc., p. 89-104 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Informatics 100%
  • Population Health 42%
  • Health Promotion 38%
  • Application 24%
  • Delivery of Health Care 24%
• 2016

  Innovative analytical methods for longitudinal medical cost data: Translating research to inform policy and practice

  Liu, L., Shih, Y. C. T. & Henderson, M. J., Jan 1 2016, Health Care Costs: Policies, Economics and Outcomes. Nova Science Publishers, Inc., p. 1-32 32 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • costs 100%
  • health care 42%
  • expenditures 31%
  • econometrics 26%
  • health plan 14%

• Machine learning as a means toward precision diagnostics and prognostics

  Sotiras, A., Gaonkar, B., Eavani, H., Honnorat, N., Varol, E., Dong, A. & Davatzikos, C., Aug 9 2016, Machine Learning and Medical Imaging. Elsevier Inc., p. 299-334 36 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Machine learning 100%
  • Biomarkers 56%
  • Medical imaging 51%
  • Dimensionality reduction 49%
  • Medicine 45%
  3 Scopus citations
• 2015

  An introduction to translational informatics and the future of knowledge-driven healthcare

  Payne, P. R. O. & Embi, P. J., Jan 1 2015, Translational Informatics: Realizing the Promise of Knowledge-Driven Healthcare. Springer-Verlag London Ltd, p. 3-19 17 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Informatics 100%
  • Delivery of Health Care 48%
  • Interdisciplinary Research 35%
  • Vacuum 30%
  • Translational Medical Research 29%
  3 Scopus citations

• A prototype of translational informatics in action

  Payne, P. R. O., Jan 1 2015, Translational Informatics: Realizing the Promise of Knowledge-Driven Healthcare. Springer-Verlag London Ltd, p. 21-31 11 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Informatics 100%
  • Biomedical Research 13%
  • Health Personnel 11%
  • Organizations 11%
  • Delivery of Health Care 8%

• Disentangling disease heterogeneity with max-margin multiple hyperplane classifier

  Varol, E., Sotiras, A. & Davatzikos, C., Oct 1 2015, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Springer Verlag, p. 702-709 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 9349).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  Open Access

  • Margin 100%
  • Classifier 98%
  • Classifiers 61%
  • Neuroimaging 49%
  • Alzheimer's Disease 49%
  5 Scopus citations

• Driving clinical and translational research using biomedical informatics

  Payne, P. R. O. & Embi, P. J., Jan 1 2015, Translational Informatics: Realizing the Promise of Knowledge-Driven Healthcare. Springer-Verlag London Ltd, p. 99-117 19 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Informatics 100%
  • Translational Medical Research 89%
  • Knowledge Management 35%
  • Data Management 35%
  • Information Management 34%
  3 Scopus citations

• Future directions for translational informatics

  Embi, P. J. & Payne, P. R. O., Jan 1 2015, Translational Informatics: Realizing the Promise of Knowledge-Driven Healthcare. Springer-Verlag London Ltd, p. 165-178 14 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Informatics 100%
  • Learning Health System 65%
  • Direction compound 57%
  • Organizational Innovation 54%
  • Medical Informatics 49%
  1 Scopus citations

• Graph-based deformable image registration

  Sotiras, A., Ou, Y., Paragios, N. & Davatzikos, C., Jan 1 2015, Handbook of Biomedical Imaging: Methodologies and Clinical Research. Springer US, p. 331-359 29 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Image registration 100%
  • Label 78%
  • Displacement 72%
  • Costs and Cost Analysis 55%
  • Image analysis 28%
  6 Scopus citations

• In silico hypothesis discovery

  Payne, P. R. O., Jan 1 2015, Translational Informatics: Realizing the Promise of Knowledge-Driven Healthcare. Springer-Verlag London Ltd, p. 129-151 23 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Computer Simulation 100%
  • Datasets 55%
  • Natural Language Processing 52%
  • Intuition 49%
  • Research Personnel 49%
  1 Scopus citations

• Joint models for longitudinal data and time-to-event occurrence

  Liu, Y. & Liu, L., Jul 24 2015, Routledge International Handbook of Advanced Quantitative Methods in Nursing Research. Taylor and Francis Inc., p. 253-263 11 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  2 Scopus citations
• 2014

  Clinical research informatics

  Payne, P. R. O., Embi, P. J. & Cimino, J. J., Jan 1 2014, Biomedical Informatics: Computer Applications in Health Care and Biomedicine: Fourth Edition. Springer London, p. 755-777 23 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
  3 Scopus citations

• Genetic component to obesity: Evidence from genetic epidemiology

  Pérusse, L., Rice, T. K. & Bouchard, C., Jan 1 2014, Handbook of Obesity: Epidemiology, Etiology, and Physiopathology, Third Edition. CRC Press, p. 91-104 14 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Molecular Epidemiology 100%
  • Obesity 59%
  • Gene-Environment Interaction 35%
  • Genes 34%
  • Metabolic Networks and Pathways 28%
  11 Scopus citations

• Genomics-Based Cancer Theranostics

  Yin, Z., Mancuso, J. J., Li, F. & Wong, S. T. C., Mar 2014, Cancer Theranostics. Elsevier Inc., p. 9-20 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Theranostic Nanomedicine 100%
  • Biotechnology 78%
  • Genomics 76%
  • Wave 70%
  • Biological Marker 68%
  2 Scopus citations
• 2013

  Dynamic pain assessment: An application of clinical infometrics to personalized pain treatment and management

  Chang, C. H., Jan 1 2013, Handbook of Pain and Palliative Care: Biobehavioral Approaches for the Life Course. Springer New York, p. 121-130 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
  1 Scopus citations
• 2011

  Essential Statistical Methods for Medical Statistics

  Rao, C. R., Miller, J. P. & Rao, D. C., Jan 10 2011, Handbook of Statistics: Epidemiology and Medical Statistics. Elsevier Inc., Vol. 27. p. 1-351 351 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Statistical method 100%
  • Statistics 71%
  • Research Methods 37%
  • Longitudinal Data Analysis 36%
  • Structural Equation Modeling 35%
  7 Scopus citations

• Measures of neurological impairment and disability in multiple sclerosis

  Cutter, G. R., Morgan, C. J., Salter, A. R., Coield, S. S. & Balcer, L. J., Dec 1 2011, Multiple Sclerosis Therapeutics, Fourth Edition. Cambridge University Press, p. 56-64 9 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Multiple Sclerosis 100%
  • Patient Care 65%
  • Clinical Trials 36%
  • United States Social Security Administration 24%
  • Anecdotes 22%

• Statistical Modeling in Biomedical Research: Longitudinal Data Analysis

  Xiong, C., Zhu, K., Yu, K. & Miller, J. P., Jan 10 2011, Handbook of Statistics: Epidemiology and Medical Statistics. Elsevier Inc., Vol. 27. p. 235-268 34 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
  1 Scopus citations
• 2010

  Authentication and authorization in cancer research systems

  Langella, S., Hastings, S., Oster, S., Payne, P. & Siebenlist, F., Dec 1 2010, Biomedical Informatics for Cancer Research. Springer US, p. 279-290 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Organizations 100%
  • Software 90%
  • Research Personnel 83%
  • Neoplasms 77%
• 2009

  Harnessing Web 2.0 for context-aware learning: The impact of social tagging system on knowledge adaption

  Fu, W. T. & Kannampallil, T., 2009, Educational Social Software for Context-Aware Learning: Collaborative Methods and Human Interaction. IGI Global, p. 98-113 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Social Web 100%
  • social system 97%
  • Students 73%
  • assimilation 65%
  • information content 42%
  1 Scopus citations

• Multidimensional pain assessment in geriatric oncology: An innovative approach

  Chang, C. H., Dec 1 2009, New Directions in Aging Research: Health and Cognition. Nova Science Publishers, Inc., p. 75-90 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • geriatrics 100%
  • Pain Measurement 88%
  • pain 85%
  • Geriatrics 84%
  • Pain 51%
• 2008

  An Overview of the Genetic Dissection of Complex Traits

  Rao, D. C., 2008, Genetic Dissection of Complex Traits. Rao, D. C. & Gu, C. (eds.). p. 3-34 32 p. (Advances in Genetics; vol. 60).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Multifactorial Inheritance 100%
  • Genome-Wide Association Study 84%
  • Dissection 69%
  • Sample Size 35%
  • Case-Control Studies 32%
  30 Scopus citations

• Characterization of LD Structures and the Utility of HapMap in Genetic Association Studies

  Gu, C. C., Yu, K. & Rao, D. C., 2008, Genetic Dissection of Complex Traits. Rao, D. C. & Gu, C. (eds.). p. 407-435 29 p. (Advances in Genetics; vol. 60).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • HapMap Project 100%
  • Linkage Disequilibrium 79%
  • Genetic Association Studies 73%
  • Genome-Wide Association Study 29%
  • Organizations 23%
  10 Scopus citations

• Familial Resemblance and Heritability

  Rice, T. K., 2008, Genetic Dissection of Complex Traits. Rao, D. C. & Gu, C. (eds.). p. 35-49 15 p. (Advances in Genetics; vol. 60).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Developmental Genes 100%
  • Gene-Environment Interaction 91%
  • Genes 88%
  • Molecular Epidemiology 85%
  • Pedigree 80%
  37 Scopus citations

• Genotyping Errors and Their Impact on Genetic Analysis

  Miller, M. B., Schwander, K. & Rao, D. C., Mar 24 2008, Genetic Dissection of Complex Traits. Rao, D. C. & Gu, C. (eds.). p. 141-152 12 p. (Advances in Genetics; vol. 60).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Genotype 100%
  • Multifactorial Inheritance 86%
  • Phenotype 84%
  • Dissection 60%
  • Datasets 55%
  8 Scopus citations

• Methods for Handling Multiple Testing

  Rice, T. K., Schork, N. J. & Rao, D. C., 2008, Genetic Dissection of Complex Traits. Rao, D. C. & Gu, C. (eds.). p. 293-308 16 p. (Advances in Genetics; vol. 60).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Genome-Wide Association Study 100%
  • Single Nucleotide Polymorphism 80%
  • Molecular Epidemiology 55%
  • Linkage Disequilibrium 54%
  • Microsatellite Repeats 50%
  148 Scopus citations
• 2007

  14 Statistical Modeling in Biomedical Research: Longitudinal Data Analysis

  Xiong, C., Zhu, K., Yu, K. & Miller, J. P., 2007, Epidemiology and Medical Statistics. Rao, C. R., Miller, J. P. & Rao, D. C. (eds.). p. 429-463 35 p. (Handbook of Statistics; vol. 27).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Longitudinal Data Analysis 100%
  • Statistical Modeling 84%
  • Statistical Model 34%
  • Statistical Models 32%
  • Model 23%
  7 Scopus citations

• 17 Early Phase Clinical Trials: Phases I and II

  Gao, F., Trinkaus, K. & Miller, J. P., 2007, Epidemiology and Medical Statistics. Rao, C. R., Miller, J. P. & Rao, D. C. (eds.). p. 513-545 33 p. (Handbook of Statistics; vol. 27).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Clinical Trials 100%
  • Formal Methods 47%
  • Statistical methods 44%
  • Therapy 39%
  • Cancer 35%
  1 Scopus citations

• Commingling and segregation analyses

  Rice, T., Jan 1 2007, Obesity: Genomics and Postgenomics. CRC Press, p. 59-76 18 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Marker 100%
  • Obesity 39%
  • Heredity 37%
  • Multifactorial Inheritance 35%
  • Genes 34%
  1 Scopus citations
• 2006

  Predictors of preclinical Alzheimer's disease

  Galvin, J. E., Powlishta, K. K., Wilkins, K., McKeel, D. W., Xiong, C., Grant, E., Storandt, M. & Morris, J. C., 2006, Research and Practice in Alzheimer's Disease. Vellas, B. & Giacobini, E. (eds.). p. 200-204 5 p. (Research and Practice in Alzheimer's Disease; vol. 11).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Dementia 100%
  • Alzheimer Disease 92%
  • Autopsy 75%
  • Cognitive Dysfunction 49%
  • Memory 43%

• Statistical Survival Analysis with Applications

  Xiong, C., Zhu, K. & Yu, K., 2006, Springer Handbooks. Springer, p. 347-367 21 p. (Springer Handbooks).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Survival Analysis 100%
  • Statistical Analysis 85%
  • Accelerated Failure Time Model 51%
  • Engineering 31%
  • Accelerated Life Test 17%
  5 Scopus citations
• 2003

  Genetics of human obesity

  Bouchard, C., Pérusse, L., Rice, T. & Rao, D. C., Jan 1 2003, Handbook of Obesity: Etiology and Pathophysiology, Second Edition. CRC Press, p. 157-200 44 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Obesity 100%
  • Western World 44%
  • Canada 32%
  • Overweight 31%
  • Epidemics 30%
  54 Scopus citations
• 2001

  18 Meta-analysis for model-free methods

  Gu, C., Province, M. A. & Rao, D. C., 2001, Advances in Genetics. Academic Press Inc., p. 255-272 18 p. (Advances in Genetics; vol. 42).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Meta-Analysis 100%
  • Multifactorial Inheritance 55%
  • Genes 35%
  • Costs and Cost Analysis 27%
  16 Scopus citations

• 19 Classification methods for confronting heterogeneity

  Province, M. A., Shannon, W. D. & Rao, D. C., 2001, Advances in Genetics. Academic Press Inc., p. 273-286 14 p. (Advances in Genetics; vol. 42).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Multifactorial Inheritance 100%
  • Dissection 34%
  • Genes 16%
  45 Scopus citations

• 26 Optimum study designs

  Gu, C. & Rao, D. C., 2001, Advances in Genetics. Academic Press Inc., p. 439-457 19 p. (Advances in Genetics; vol. 42).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Multifactorial Inheritance 100%
  • Chromosome Mapping 49%
  • Uncertainty 37%
  • Sample Size 35%
  • Cost-Benefit Analysis 34%
  14 Scopus citations

• 29 False positives and false negatives in genome scans

  Rao, D. C. & Gu, C., 2001, Advances in Genetics. Academic Press Inc., p. 487-498 12 p. (Advances in Genetics; vol. 42).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Genome 100%
  47 Scopus citations

• 3 Genetic dissection of complex traits: An overview

  Rao, D. C., 2001, Advances in Genetics. Academic Press Inc., p. 13-34 22 p. (Advances in Genetics; vol. 42).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Multifactorial Inheritance 100%
  • Dissection 69%
  • Sample Size 43%
  • Thinking 15%
  • Genes 13%
  32 Scopus citations

• 4 Familial resemblance and heritability

  Rice, T. K. & Borecki, I. B., 2001, Advances in Genetics. Academic Press Inc., p. 35-44 10 p. (Advances in Genetics; vol. 42).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Genes 100%
  • Developmental Genes 84%
  • Gene-Environment Interaction 77%
  • Twin Studies 76%
  • Molecular Epidemiology 72%
  28 Scopus citations

• Genetics of energy and nutrient intake

  Rice, T., Pérusse, L. & Bouchard, C., Jan 1 2001, Handbook of Nutrition and Food. CRC Press, p. 603-619 17 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Energy Intake 100%
  • Nutrients 84%
  • Eating 75%
  • Food Preferences 66%
  • Dyslipidemias 48%
  3 Scopus citations