Institute for Informatics, Data Science and Biostatistics

Search results

  • 2016

    Genetic association of left ventricular mass assessed by M-mode and two-dimensional echocardiography

    Barve, R. A., Gu, C. C., Yang, W., Chu, J., Dávila-Román, V. G. & De Las Fuentes, L., Jan 1 2016, In: Journal of Hypertension. 34, 1, p. 88-96 9 p.

    Research output: Contribution to journal › Article › peer-review

    4 Scopus citations

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Pattaro, C., Teumer, A., Gorski, M., Chu, A. Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M. H., Pers, T. H., Johnson, A. D., Ko, Y. A., Fuchsberger, C., Tayo, B., & 678 othersNalls, M., Feitosa, M. F., Isaacs, A., Dehghan, A., D'Adamo, P., Adeyemo, A., Dieffenbach, A. K., Zonderman, A. B., Nolte, I. M., Van Der Most, P. J., Wright, A. F., Shuldiner, A. R., Morrison, A. C., Hofman, A., Smith, A. V., Dreisbach, A. W., Franke, A., Uitterlinden, A. G., Metspalu, A., Tonjes, A., Lupo, A., Robino, A., Johansson, Å., Demirkan, A., Kollerits, B., Freedman, B. I., Ponte, B., Oostra, B. A., Paulweber, B., Krämer, B. K., Mitchell, B. D., Buckley, B. M., Peralta, C. A., Hayward, C., Helmer, C., Rotimi, C. N., Shaffer, C. M., Müller, C., Sala, C., Van Duijn, C. M., Saint-Pierre, A., Ackermann, D., Shriner, D., Ruggiero, D., Toniolo, D., Lu, Y., Cusi, D., Czamara, D., Ellinghaus, D., Siscovick, D. S., Ruderfer, D., Gieger, C., Grallert, H., Rochtchina, E., Atkinson, E. J., Holliday, E. G., Boerwinkle, E., Salvi, E., Bottinger, E. P., Murgia, F., Rivadeneira, F., Ernst, F., Kronenberg, F., Hu, F. B., Navis, G. J., Curhan, G. C., Ehret, G. B., Homuth, G., Coassin, S., Thun, G. A., Pistis, G., Gambaro, G., Malerba, G., Montgomery, G. W., Eiriksdottir, G., Jacobs, G., Li, G., Wichmann, H. E., Campbell, H., Schmidt, H., Wallaschofski, H., Völzke, H., Brenner, H., Kroemer, H. K., Kramer, H., Lin, H., Leach, I. M., Ford, I., Guessous, I., Rudan, I., Prokopenko, I., Borecki, I., Heid, I. M., Kolcic, I., Persico, I., Jukema, J. W., Wilson, J. F., Felix, J. F., Divers, J., Lambert, J. C., Stafford, J. M., Gaspoz, J. M., Smith, J. A., Faul, J. D., Wang, J. J., Ding, J., Hirschhorn, J. N., Attia, J., Whitfield, J. B., Chalmers, J., Viikari, J., Coresh, J., Denny, J. C., Karjalainen, J., Fernandes, J. K., Endlich, K., Butterbach, K., Keene, K. L., Lohman, K., Portas, L., Launer, L. J., Lyytikäinen, L. P., Yengo, L., Franke, L., Ferrucci, L., Rose, L. M., Kedenko, L., Rao, M., Struchalin, M., Kleber, M. E., Cavalieri, M., Haun, M., Cornelis, M. C., Ciullo, M., Pirastu, M., De Andrade, M., McEvoy, M. A., Woodward, M., Adam, M., Cocca, M., Nauck, M., Imboden, M., Waldenberger, M., Pruijm, M., Metzger, M., Stumvoll, M., Evans, M. K., Sale, M. M., Kähönen, M., Boban, M., Bochud, M., Rheinberger, M., Verweij, N., Bouatia-Naji, N., Martin, N. G., Hastie, N., Probst-Hensch, N., Soranzo, N., Devuyst, O., Raitakari, O., Gottesman, O., Franco, O. H., Polasek, O., Gasparini, P., Munroe, P. B., Ridker, P. M., Mitchell, P., Muntner, P., Meisinger, C., Smit, J. H., Abecasis, G. R., Adair, L. S., Alexander, M., Altshuler, D., Amin, N., Arking, D. E., Arora, P., Aulchenko, Y., Bakker, S. J. L., Bandinelli, S., Barroso, I., Beckmann, J. S., Beilby, J. P., Bergman, R. N., Bergmann, S., Bis, J. C., Boehnke, M., Bonnycastle, L. L., Bornstein, S. R., Bots, M. L., Bragg-Gresham, J. L., Brand, S. M., Brand, E., Braund, P. S., Brown, M. J., Burton, P. R., Casas, J. P., Caulfield, M. J., Chakravarti, A., Chambers, J. C., Chandak, G. R., Chang, Y. P. C., Charchar, F. J., Chaturvedi, N., Cho, Y. S., Clarke, R., Collins, F. S., Collins, R., Connell, J. M., Cooper, J. A., Cooper, M. N., Cooper, R. S., Corsi, A. M., Dörr, M., Dahgam, S., Danesh, J., Smith, G. D., Day, I. N. M., Deloukas, P., Denniff, M., Dominiczak, A. F., Dong, Y., Doumatey, A., Elliott, P., Elosua, R., Erdmann, J., Eyheramendy, S., Farrall, M., Fava, C., Forrester, T., Fowkes, F. G. R., Fox, E. R., Frayling, T. M., Galan, P., Ganesh, S. K., Garcia, M., Gaunt, T. R., Glazer, N. L., Go, M. J., Goel, A., Grässler, J., Grobbee, D. E., Groop, L., Guarrera, S., Guo, X., Hadley, D., Hamsten, A., Han, B. G., Hardy, R., Hartikainen, A. L., Heath, S., Heckbert, S. R., Hedblad, B., Hercberg, S., Hernandez, D., Hicks, A. A., Hilton, G., Hingorani, A. D., Hoffman Bolton, J. A., Hopewell, J. C., Howard, P., Humphries, S. E., Hunt, S. C., Hveem, K., Ikram, M. A., Islam, M., Iwai, N., Jarvelin, M. R., Jackson, A. U., Jafar, T. H., Janipalli, C. S., Johnson, T., Kathiresan, S., Khaw, K. T., Kim, H. L., Kinra, S., Kita, Y., Kivimaki, M., Kooner, J. S., Kumar, M. J. K., Kuh, D., Kulkarni, S. R., Kumari, M., Kuusisto, J., Kuznetsova, T., Laakso, M., Laan, M., Laitinen, J., Lakatta, E. G., Langefeld, C. D., Larson, M. G., Lathrop, M., Lawlor, D. A., Lawrence, R. W., Lee, J. Y., Lee, N. R., Levy, D., Li, Y., Longstreth, W. T., Luan, J., Lucas, G., Ludwig, B., Mangino, M., Mani, K. R., Marmot, M. G., Mattace-Raso, F. U. S., Matullo, G., McArdle, W. L., McKenzie, C. A., Meitinger, T., Melander, O., Meneton, P., Meschia, J. F., Miki, T., Milaneschi, Y., Mohlke, K. L., Mooser, V., Morken, M. A., Morris, R. W., Mosley, T. H., Najjar, S., Narisu, N., Newton-Cheh, C., Nguyen, K. D. H., Nilsson, P., Nyberg, F., O'Donnell, C. J., Ogihara, T., Ohkubo, T., Okamura, T., Ong, R. T. H., Ongen, H., Onland-Moret, N. C., O'Reilly, P. F., Org, E., Orru, M., Palmas, W., Palmen, J., Palmer, L. J., Palmer, N. D., Parker, A. N., Peden, J. F., Peltonen, L., Perola, M., Pihur, V., Platou, C. G. P., Plump, A., Prabhakaran, D., Psaty, B. M., Raffel, L. J., Rao, D. C., Rasheed, A., Ricceri, F., Rice, K. M., Rosengren, A., Rotter, J. I., Rudock, M. E., Sõber, S., Salako, T., Saleheen, D., Salomaa, V., Samani, N. J., Schwartz, S. M., Schwarz, P. E. H., Scott, L. J., Scott, J., Scuteri, A., Sehmi, J. S., Seielstad, M., Seshadri, S., Sharma, P., Shaw-Hawkins, S., Shi, G., Shrine, N. R. G., Sijbrands, E. J. G., Sim, X., Singleton, A., Sjögren, M., Smith, N. L., Artigas, M. S., Spector, T. D., Staessen, J. A., Stancakova, A., Steinle, N. I., Strachan, D. P., Stringham, H. M., Sun, Y. V., Swift, A. J., Tabara, Y., Tai, E. S., Talmud, P. J., Taylor, A., Terzic, J., Thelle, D. S., Tobin, M. D., Tomaszewski, M., Tripathy, V., Tuomilehto, J., Tzoulaki, I., Uda, M., Ueshima, H., Uiterwaal, C. S. P. M., Umemura, S., Van Der Harst, P., Van Der Schouw, Y. T., Van Gilst, W. H., Vartiainen, E., Vasan, R. S., Veldre, G., Verwoert, G. C., Viigimaa, M., Vinay, D. G., Vineis, P., Voight, B. F., Vollenweider, P., Wagenknecht, L. E., Wain, L. V., Wang, X., Wang, T. J., Wareham, N. J., Watkins, H., Weder, A. B., Whincup, P. H., Wiggins, K. L., Witteman, J. C. M., Wong, A., Wu, Y., Yajnik, C. S., Yao, J., Young, J. H., Zelenika, D., Zhai, G., Zhang, W., Zhang, F., Zhao, J. H., Zhu, H., Zhu, X., Zitting, P., Zukowska-Szczechowska, E., Okada, Y., Wu, J. Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S. C., Wong, T. Y., Liu, J., Young, T. L., Aung, T., Teo, Y. Y., Kim, Y. J., Kang, D., Chen, C. H., Tsai, F. J., Chang, L. C., Fann, S. J. C., Mei, H., Hixson, J. E., Chen, S., Katsuya, T., Isono, M., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y. T., Tanaka, T., Reilly, M. P., Schunkert, H., Assimes, T. L., Hall, A., Hengstenberg, C., König, I. R., Laaksonen, R., McPherson, R., Thompson, J. R., Thorsteinsdottir, U., Ziegler, A., Absher, D., Chen, L., Cupples, L. A., Halperin, E., Li, M., Musunuru, K., Preuss, M., Schillert, A., Thorleifsson, G., Wells, G. A., Holm, H., Roberts, R., Stewart, A. F. R., Fortmann, S., Go, A., Hlatky, M., Iribarren, C., Knowles, J., Myers, R., Quertermous, T., Sidney, S., Risch, N., Tang, H., Blankenberg, S., Schnabel, R., Sinning, C., Lackner, K. J., Tiret, L., Nicaud, V., Cambien, F., Bickel, C., Rupprecht, H. J., Perret, C., Proust, C., Münzel, T. F., Barbalic, M., Chen, I. Y. D., Demissie-Banjaw, S., Folsom, A., Lumley, T., Marciante, K., Taylor, K. D., Volcik, K., Gretarsdottir, S., Gulcher, J. R., Kong, A., Stefansson, K., Thorgeirsson, G., Andersen, K., Fischer, M., Grosshennig, A., Linsel-Nitschke, P., Stark, K., Schreiber, S., Aherrahrou, Z., Bruse, P., Doering, A., Klopp, N., Diemert, P., Loley, C., Medack, A., Nahrstedt, J., Peters, A., Wagner, A. K., Willenborg, C., Böhm, B. O., Dobnig, H., Grammer, T. B., Hoffmann, M. M., Meinitzer, A., Winkelmann, B. R., Pilz, S., Renner, W., Scharnagl, H., Stojakovic, T., Tomaschitz, A., Winkler, K., Guiducci, C., Burtt, N., Gabriel, S. B., Dandona, S., Jarinova, O., Qu, L., Wilensky, R., Matthai, W., Hakonarson, H. H., Devaney, J., Burnett, M. S., Pichard, A. D., Kent, K. M., Satler, L., Lindsay, J. M., Waksman, R., Knouff, C. W., Waterworth, D. M., Walker, M. C., Epstein, S. E., Rader, D. J., Nelson, C. P., Wright, B. J., Balmforth, A. J., Ball, S. G., Loehr, L. R., Rosamond, W. D., Benjamin, E., Haritunians, T., Couper, D., Murabito, J., Wang, Y. A., Stricker, B. H., Chang, P. P., Willerson, J. T., Felix, S. B., Watzinger, N., Aragam, J., Zweiker, R., Lind, L., Rodeheffer, R. J., Greiser, K. H., Deckers, J. W., Stritzke, J., Ingelsson, E., Kullo, I., Haerting, J., Reffelmann, T., Redfield, M. M., Werdan, K., Mitchell, G. F., Arnett, D. K., Gottdiener, J. S., Blettner, M., Friedrich, N., Kovacs, P., Wild, P. S., Froguel, P., Rettig, R., Mägi, R., Biffar, R., Schmidt, R., Middelberg, R. P. S., Carroll, R. J., Penninx, B. W., Scott, R. J., Katz, R., Sedaghat, S., Wild, S. H., Kardia, S. L. R., Ulivi, S., Hwang, S. J., Enroth, S., Kloiber, S., Trompet, S., Stengel, B., Hancock, S. J., Turner, S. T., Rosas, S. E., Stracke, S., Harris, T. B., Zeller, T., Zemunik, T., Lehtimäki, T., Illig, T., Aspelund, T., Nikopensius, T., Esko, T., Tanaka, T., Gyllensten, U., Völker, U., Emilsson, V., Vitart, V., Aalto, V., Gudnason, V., Chouraki, V., Chen, W. M., Igl, W., März, W., Koenig, W., Lieb, W., Loos, R. J. F., Liu, Y., Snieder, H., Pramstaller, P. P., Parsa, A., O'Connell, J. R., Susztak, K., Hamet, P., Tremblay, J., De Boer, I. H., Böger, C. A., Goessling, W., Chasman, D. I., Köttgen, A., Kao, W. H. L. & Fox, C. S., Jan 21 2016, In: Nature communications. 7, 10023.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    305 Scopus citations

  • Genetics and population analysis: Estimating and testing high-dimensional mediation effects in epigenetic studies

    Zhang, H., Zheng, Y., Zhang, Z., Gao, T., Joyce, B., Yoon, G., Zhang, W., Schwartz, J., Just, A., Colicino, E., Vokonas, P., Zhao, L., Lv, J., Baccarelli, A., Hou, L. & Liu, L., Oct 15 2016, In: Bioinformatics. 32, 20, p. 3150-3154 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    73 Scopus citations

  • Genetic Susceptibility to Lipid Levels and Lipid Change over Time and Risk of Incident Hyperlipidemia in Chinese Populations

    Lu, X., Huang, J., Mo, Z., He, J., Wang, L., Yang, X., Tan, A., Chen, S., Chen, J., Charles Gu, C., Chen, J., Li, Y., Zhao, L., Li, H., Hao, Y., Li, J., Hixson, J. E., Li, Y., Cheng, M., Liu, X., & 18 othersCao, J., Liu, F., Huang, C., Shen, C., Shen, J., Yu, L., Xu, L., Mu, J., Wu, X., Ji, X., Guo, D., Zhou, Z., Yang, Z., Wang, R., Yang, J., Yan, W., Peng, X. & Gu, D., Feb 1 2016, In: Circulation: Cardiovascular Genetics. 9, 1, p. 37-44 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    42 Scopus citations

  • Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference

    Wen, W., Kato, N., Hwang, J. Y., Guo, X., Tabara, Y., Li, H., Dorajoo, R., Yang, X., Tsai, F. J., Li, S., Wu, Y., Wu, T., Kim, S., Guo, X., Liang, J., Shungin, D., Adair, L. S., Akiyama, K., Allison, M., Cai, Q., & 56 othersChang, L. C., Chen, C. H., Chen, Y. T., Cho, Y. S., Choi, B. Y., Gao, Y., Go, M. J., Gu, D., Han, B. G., He, M., Hixson, J. E., Hu, Y., Huang, T., Isono, M., Jung, K. J., Kang, D., Kim, Y. J., Kita, Y., Lee, J., Lee, N. R., Lee, J., Wang, Y., Liu, J. J., Long, J., Moon, S., Nakamura, Y., Nakatochi, M., Ohnaka, K., Rao, D., Shi, J., Sull, J. W., Tan, A., Ueshima, H., Wu, C., Xiang, Y. B., Yamamoto, K., Yao, J., Ye, X., Yokota, M., Zhang, X., Zheng, Y., Qi, L., Rotter, J. I., Jee, S. H., Lin, D., Mohlke, K. L., He, J., Mo, Z., Wu, J. Y., Tai, E. S., Lin, X., Miki, T., Kim, B. J., Takeuchi, F., Zheng, W. & Shu, X. O., Jan 20 2016, In: Scientific reports. 6, 17958.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    43 Scopus citations

  • Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat

    Sung, Y. J., Pérusse, L., Sarzynski, M. A., Fornage, M., Sidney, S., Sternfeld, B., Rice, T., Terry, J. G., Jacobs, D. R., Katzmarzyk, P., Curran, J. E., Jeffrey Carr, J., Blangero, J., Ghosh, S., Després, J. P., Rankinen, T., Rao, D. C. & Bouchard, C., Apr 1 2016, In: International Journal of Obesity. 40, 4, p. 662-674 13 p.

    Research output: Contribution to journal › Article › peer-review

    62 Scopus citations

  • Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study

    Li, C., He, J., Chen, J., Zhao, J., Gu, D., Hixson, J. E., Rao, D. C., Jaquish, C. E., Gu, C. C., Chen, J., Huang, J., Chen, S. & Kelly, T. N., Aug 1 2016, In: Hypertension. 68, 2, p. 348-355 8 p.

    Research output: Contribution to journal › Article › peer-review

    32 Scopus citations

  • Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

    Kilpeläinen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, Å. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L. P., Eriksson, J., & 157 othersHenneman, P., Lahti, J., Tanaka, T., Luan, J., Fabiola Del, G. M., Pasko, D., Renström, F., Willems, S. M., Mahajan, A., Rose, L. M., Guo, X., Liu, Y., Kleber, M. E., Pérusse, L., Gaunt, T., Ahluwalia, T. S., Ju Sung, Y., Ramos, Y. F., Amin, N., Amuzu, A., Barroso, I., Bellis, C., Blangero, J., Buckley, B. M., Böhringer, S., I Chen, Y. D., De Craen, A. J. N., Crosslin, D. R., Dale, C. E., Dastani, Z., Day, F. R., Deelen, J., Delgado, G. E., Demirkan, A., Finucane, F. M., Ford, I., Garcia, M. E., Gieger, C., Gustafsson, S., Hallmans, G., Hankinson, S. E., Havulinna, A. S., Herder, C., Hernandez, D., Hicks, A. A., Hunter, D. J., Illig, T., Ingelsson, E., Ioan-Facsinay, A., Jansson, J. O., Jenny, N. S., Jørgensen, M. E., Jørgensen, T., Karlsson, M., Koenig, W., Kraft, P., Kwekkeboom, J., Laatikainen, T., Ladwig, K. H., Leduc, C. A., Lowe, G., Lu, Y., Marques-Vidal, P., Meisinger, C., Menni, C., Morris, A. P., Myers, R. H., Männistö, S., Nalls, M. A., Paternoster, L., Peters, A., Pradhan, A. D., Rankinen, T., Rasmussen-Torvik, L. J., Rathmann, W., Rice, T. K., Brent Richards, J., Ridker, P. M., Sattar, N., Savage, D. B., Söderberg, S., Timpson, N. J., Vandenput, L., Van Heemst, D., Uh, H. W., Vohl, M. C., Walker, M., Wichmann, H. E., Widén, E., Wood, A. R., Yao, J., Zeller, T., Zhang, Y., Meulenbelt, I., Kloppenburg, M., Astrup, A., Sørensen, T. I. A., Sarzynski, M. A., Rao, D. C., Jousilahti, P., Vartiainen, E., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Kajantie, E., Osmond, C., Palotie, A., Eriksson, J. G., Heliövaara, M., Knekt, P. B., Koskinen, S., Jula, A., Perola, M., Huupponen, R. K., Viikari, J. S., Kähönen, M., Lehtimäki, T., Raitakari, O. T., Mellström, D., Lorentzon, M., Casas, J. P., Bandinelli, S., März, W., Isaacs, A., Van Dijk, K. W., Van Duijn, C. M., Harris, T. B., Bouchard, C., Allison, M. A., Chasman, D. I., Ohlsson, C., Lind, L., Scott, R. A., Langenberg, C., Wareham, N. J., Ferrucci, L., Frayling, T. M., Pramstaller, P. P., Borecki, I. B., Waterworth, D. M., Bergmann, S., Waeber, G., Vollenweider, P., Vestergaard, H., Hansen, T., Pedersen, O., Hu, F. B., Eline Slagboom, P., Grallert, H., Spector, T. D., Jukema, J. W., Klein, R. J., Schadt, E. E., Franks, P. W., Lindgren, C. M., Leibel, R. L. & Loos, R. J. F., Feb 1 2016, In: Nature communications. 7, 10494.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    111 Scopus citations

  • GLISTRboost: Combining multimodal MRI segmentation, registration, and biophysical tumor growth modeling with gradient boosting machines for glioma segmentation

    Bakas, S., Zeng, K., Sotiras, A., Rathore, S., Akbari, H., Gaonkar, B., Rozycki, M., Pati, S. & Davatzikos, C., Jan 1 2016, Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - 1st International Workshop, Brainles 2015 Held in Conjunction with MICCAI 2015, Revised Selected Papers. Reyes, M., Crimi, A., Maier, O., Maier, O., Handels, H. & Menze, B. (eds.). Springer Verlag, p. 144-155 12 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 9556).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

    69 Scopus citations

  • Global microRNA profiling for diagnostic appraisal of melanocytic Spitz tumors

    Latchana, N., Regan, K., Howard, J. H., Aldrink, J. H., Ranalli, M. A., Peters, S. B., Zhang, X., Gru, A., Payne, P. R. O., Suarez-Kelly, L. P. & Carson, W. E., Oct 1 2016, In: Journal of Surgical Research. 205, 2, p. 350-358 9 p.

    Research output: Contribution to journal › Article › peer-review

    16 Scopus citations

  • Health insurance affects the use of disease-modifying therapy in multiple sclerosis

    Wang, G., Marrie, R. A., Salter, A. R., Fox, R., Cofield, S. S., Tyry, T. & Cutter, G. R., Jul 26 2016, In: Neurology. 87, 4, p. 365-374 10 p.

    Research output: Contribution to journal › Article › peer-review

    20 Scopus citations

  • Health insurance trajectories and long-term survival after heart transplantation

    Tumin, D., Foraker, R. E., Smith, S., Tobias, J. D. & Hayes, D., Sep 1 2016, In: Circulation: Cardiovascular Quality and Outcomes. 9, 5, p. 576-584 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    24 Scopus citations

  • Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

    Harrison, J. S., Cornett, E. M., Goldfarb, D., Darosa, P. A., Li, Z. M., Yan, F., Dickson, B. M., Guo, A. H., Cantu, D. V., Kaustov, L., Brown, P. J., Arrowsmith, C. H., Erie, D. A., Major, M. B., Klevit, R. E., Krajewski, K., Kuhlman, B., Strahl, B. D. & Rothbart, S. B., Sep 6 2016, In: eLife. 5, Se, e17101.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    85 Scopus citations

  • High-fidelity analysis of perioperative QTc prolongation

    Duma, A., Pal, S., Helsten, D., Stein, P. K., Miller, J. P. & Nagele, P., Feb 1 2016, In: Anesthesia and analgesia. 122, 2, p. 439-448 10 p.

    Research output: Contribution to journal › Article › peer-review

    11 Scopus citations

  • Human epithelial NA+ channel missense variants identified in the GenSalt study alter channel activity

    Ray, E. C., Chen, J., Kelly, T. N., He, J., Hamm, L. L., Gu, D., Shimmin, L. C., Hixson, J. E., Rao, D. C., Sheng, S. & Kleyman, T. R., 2016, In: American Journal of Physiology - Renal Physiology. 311, 5, p. F908-F914

    Research output: Contribution to journal › Article › peer-review

    15 Scopus citations

  • Identification, characterization, and grounding of gradable terms in clinical text

    Shivade, C., De Marneffe, M. C., Fosler-Lussier, E. & Lai, A. M., 2016, BioNLP 2016 - Proceedings of the 15th Workshop on Biomedical Natural Language Processing. Cohen, K. B., Demner-Fushman, D., Ananiadou, S. & Tsujii, J. (eds.). Association for Computational Linguistics (ACL), p. 17-26 10 p. (BioNLP 2016 - Proceedings of the 15th Workshop on Biomedical Natural Language Processing).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

    5 Scopus citations

  • Identification and characterization of MCM3 as a kelch-like ECH-associated protein 1 (KEAP1) substrate

    Mulvaney, K. M., Matson, J. P., Siesser, P. F., Tamir, T. Y., Goldfarb, D., Jacobs, T. M., Cloer, E. W., Harrison, J. S., Vaziri, C., Cook, J. G. & Major, M. B., Nov 4 2016, In: Journal of Biological Chemistry. 291, 45, p. 23719-23733 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    56 Scopus citations

  • Imaging and cerebrospinal fluid biomarkers in early preclinical alzheimer disease

    Vlassenko, A. G., McCue, L., Jasielec, M. S., Su, Y., Gordon, B. A., Xiong, C., Holtzman, D. M., Benzinger, T. L. S., Morris, J. C. & Fagan, A. M., Sep 1 2016, In: Annals of neurology. 80, 3, p. 379-387 9 p.

    Research output: Contribution to journal › Article › peer-review

    68 Scopus citations

  • Impact of structured rounding tools on time allocation during multidisciplinary rounds: An observational study

    Abraham, J., Kannampallil, T. G., Patel, V. L., Patel, B. & Almoosa, K. F., Jul 1 2016, In: JMIR Human Factors. 3, 2, e29.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5 Scopus citations

  • Innovative analytical methods for longitudinal medical cost data: Translating research to inform policy and practice

    Liu, L., Shih, Y. C. T. & Henderson, M. J., Jan 1 2016, Health Care Costs: Policies, Economics and Outcomes. Nova Science Publishers, Inc., p. 1-32 32 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Insurance status by region at the time of heart transplantation: Implications for survival

    Foraker, R. E., Tumin, D., Smith, S., Tobias, J. D. & Hayes, D., Dec 1 2016, In: Journal of Heart and Lung Transplantation. 35, 12, p. 1480-1486 7 p.

    Research output: Contribution to journal › Article › peer-review

    7 Scopus citations

  • Integrative analysis of somatic mutations and transcriptomic data to functionally stratify breast cancer patients

    Zhang, J., Abrams, Z., Parvin, J. D. & Huang, K., Aug 22 2016, In: BMC genomics. 17, 513.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations

  • Joint frailty models for zero-inflated recurrent events in the presence of a terminal event

    Liu, L., Huang, X., Yaroshinsky, A. & Cormier, J. N., Mar 1 2016, In: Biometrics. 72, 1, p. 204-214 11 p.

    Research output: Contribution to journal › Article › peer-review

    30 Scopus citations

  • Junior Faculty Career Development Through an NHLBI Program to Increase Diversity in Cardiovascular Health-Related Research

    Fabris, F., Rice, T. K., Jeffe, D. B., Czajkowski, S. M., Boyington, J. & Boutjdir, M., May 17 2016, In: Journal of the American College of Cardiology. 67, 19, p. 2312-2313 2 p.

    Research output: Contribution to journal › Letter › peer-review

    Open Access
    8 Scopus citations

  • Longitudinal relationships among biomarkers for Alzheimer disease in the Adult Children Study

    Xiong, C., Jasielec, M. S., Weng, H., Fagan, A. M., Benzinger, T. L. S., Head, D., Hassenstab, J., Grant, E., Sutphen, C. L., Buckles, V., Moulder, K. L. & Morris, J. C., Apr 19 2016, In: Neurology. 86, 16, p. 1499-1506 8 p.

    Research output: Contribution to journal › Article › peer-review

    28 Scopus citations

  • Machine learning as a means toward precision diagnostics and prognostics

    Sotiras, A., Gaonkar, B., Eavani, H., Honnorat, N., Varol, E., Dong, A. & Davatzikos, C., Aug 9 2016, Machine Learning and Medical Imaging. Elsevier Inc., p. 299-334 36 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

    3 Scopus citations

  • Methodological framework for evaluating clinical processes: A cognitive informatics perspective

    Kannampallil, T. G., Abraham, J. & Patel, V. L., Dec 1 2016, In: Journal of Biomedical Informatics. 64, p. 342-351 10 p.

    Research output: Contribution to journal › Comment/debate

    9 Scopus citations

  • MicroRNA profiling of patient plasma for clinical trials using bioinformatics and biostatistical approaches

    Markowitz, J., Abrams, Z., Jacob, N. K., Zhang, X., Hassani, J. N., Latchana, N., Wei, L., Regan, K. E., Brooks, T. R., Uppati, S. R., Levine, K. M., Bekaii-Saab, T., Kendra, K. L., Lesinski, G. B., Howard, J. H., Olencki, T., Payne, P. R. & Carson, W. E., Sep 29 2016, In: OncoTargets and Therapy. 9, p. 5931-5941 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    4 Scopus citations

  • MSAcquisitionSimulator: Data-dependent acquisition simulator for LC-MS shotgun proteomics

    Goldfarb, D., Wang, W. & Major, M. B., Apr 15 2016, In: Bioinformatics. 32, 8, p. 1269-1271 3 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    6 Scopus citations

  • NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers

    Murakami, K., Günesdogan, U., Zylicz, J. J., Tang, W. W. C., Sengupta, R., Kobayashi, T., Kim, S., Butler, R., Dietmann, S. & Surani, M. A., Jan 21 2016, In: Nature. 529, 7586, p. 403-407 5 p.

    Research output: Contribution to journal › Article › peer-review

    121 Scopus citations

  • Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS)

    Dominantly Inherited Alzheimer Network (DIAN), Dec 1 2016, In: The Lancet Neurology. 15, 13, p. 1317-1325 9 p.

    Research output: Contribution to journal › Article › peer-review

    68 Scopus citations

  • New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

    Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, Å. K., Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S., & 239 othersLagou, V., Li, R., Li, X., Locke, A., Lu, C., Mägi, R., Perry, J. R. B., Pers, T. H., Qi, Q., Sanna, M., Schmidt, E. M., Scott, W. R., Shungin, D., Teumer, A., Vinkhuyzen, A. A. E., Walker, R. W., Westra, H. J., Zhang, M., Zhang, W., Zhao, J. H., Zhu, Z., Afzal, U., Ahluwalia, T. S., Bakker, S. J. L., Bellis, C., Bonnefond, A., Borodulin, K., Buchman, A. S., Cederholm, T., Choh, A. C., Choi, H. J., Curran, J. E., De Groot, L. C. P. G. M., De Jager, P. L., Dhonukshe-Rutten, R. A. M., Enneman, A. W., Eury, E., Evans, D. S., Forsen, T., Friedrich, N., Fumeron, F., Garcia, M. E., Gärtner, S., Han, B. G., Havulinna, A. S., Hayward, C., Hernandez, D., Hillege, H., Ittermann, T., Kent, J. W., Kolcic, I., Laatikainen, T., Lahti, J., Leach, I. M., Lee, C. G., Lee, J. Y., Liu, T., Liu, Y., Lobbens, S., Loh, M., Lyytikaïnen, L. P., Medina-Gomez, C., Michaëlsson, K., Nalls, M. A., Nielson, C. M., Oozageer, L., Pascoe, L., Paternoster, L., Polašek, O., Ripatti, S., Sarzynski, M. A., Shin, C. S., Naranäiä, N. S., Spira, D., Srikanth, P., Steinhagen-Thiessen, E., Sung, Y. J., Swart, K. M. A., Taittonen, L., Tanaka, T., Tikkanen, E., Van Der Velde, N., Van Schoor, N. M., Verweij, N., Wright, A. F., Yu, L., Zmuda, J. M., Eklund, N., Forrester, T., Grarup, N., Jackson, A. U., Kristiansson, K., Kuulasmaa, T., Kuusisto, J., Lichtner, P., Luan, J., Mahajan, A., Männistö, S., Palmer, C. D., Ried, J. S., Scott, R. A., Stancáková, A., Wagner, P. J., Demirkan, A., Döring, A., Gudnason, V., Kiel, D. P., Kühnel, B., Mangino, M., McKnight, B., Menni, C., O'Connell, J. R., Oostra, B. A., Shuldiner, A. R., Song, K., Vandenput, L., Van Duijn, C. M., Vollenweider, P., White, C. C., Boehnke, M., Boettcher, Y., Cooper, R. S., Forouhi, N. G., Gieger, C., Grallert, H., Hingorani, A., Jørgensen, T., Jousilahti, P., Kivimaki, M., Kumari, M., Laakso, M., Langenberg, C., Linneberg, A., Luke, A., McKenzie, C. A., Palotie, A., Pedersen, O., Peters, A., Strauch, K., Tayo, B. O., Wareham, N. J., Bennett, D. A., Bertram, L., Blangero, J., Blüher, M., Bouchard, C., Campbell, H., Cho, N. H., Cummings, S. R., Czerwinski, S. A., Demuth, I., Eckardt, R., Eriksson, J. G., Ferrucci, L., Franco, O. H., Froguel, P., Gansevoort, R. T., Hansen, T., Harris, T. B., Hastie, N., Heliövaara, M., Hofman, A., Jordan, J. M., Jula, A., Kähönen, M., Kajantie, E., Knekt, P. B., Koskinen, S., Kovacs, P., Lehtimäki, T., Lind, L., Liu, Y., Orwoll, E. S., Osmond, C., Perola, M., Pérusse, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Rivadeneira, F., Rudan, I., Salomaa, V., Sørensen, T. I. A., Stumvoll, M., Tönjes, A., Towne, B., Tranah, G. J., Tremblay, A., Uitterlinden, A. G., Van Der Harst, P., Vartiainen, E., Viikari, J. S., Vitart, V., Vohl, M. C., Völzke, H., Walker, M., Wallaschofski, H., Wild, S., Wilson, J. F., Yengo, L., Bishop, D. T., Borecki, I. B., Chambers, J. C., Cupples, L. A., Dehghan, A., Deloukas, P., Fatemifar, G., Fox, C., Furey, T. S., Franke, L., Han, J., Hunter, D. J., Karjalainen, J., Karpe, F., Kaplan, R. C., Kooner, J. S., McCarthy, M. I., Murabito, J. M., Morris, A. P., Bishop, J. A. N., North, K. E., Ohlsson, C., Ong, K. K., Prokopenko, I., Richards, J. B., Schadt, E. E., Spector, T. D., Widén, E., Willer, C. J., Yang, J., Ingelsson, E., Mohlke, K. L., Hirschhorn, J. N., Pospisilik, J. A., Zillikens, M. C., Lindgren, C., Kilpelaïnen, T. O. & Loos, R. J. F., Feb 1 2016, In: Nature communications. 7, 10495.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    187 Scopus citations

  • No survival benefit to gaining private health insurance coverage for post-lung transplant care in adults with cystic fibrosis

    Tumin, D., Foraker, R. E., Tobias, J. D. & Hayes, D., Mar 1 2016, In: Clinical Transplantation. 30, 3, p. 320-327 8 p.

    Research output: Contribution to journal › Article › peer-review

    7 Scopus citations

  • Obliterative Bronchiolitis

    Aguilar, P. R., Michelson, A. P. & Isakow, W., Feb 1 2016, In: Transplantation. 100, 2, p. 272-283 12 p.

    Research output: Contribution to journal › Review article › peer-review

    36 Scopus citations

  • Particulate air pollution exposure and expression of viral and human MicroRNAs in blood: The beijing truck driver air pollution study

    Hou, L., Barupal, J., Zhang, W., Zheng, Y., Liu, L., Zhang, X., Dou, C., McCracken, J. P., Díaz, A., Motta, V., Sanchez-Guerra, M., Wolf, K. R., Bertazzi, P. A., Schwartz, J. D., Wang, S. & Baccarelli, A. A., Mar 2016, In: Environmental Health Perspectives. 124, 3, p. 344-350 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    32 Scopus citations

  • Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study

    Chatterjee, P., Lim, W. L. F., Shui, G., Gupta, V. B., James, I., Fagan, A. M., Xiong, C., Sohrabi, H. R., Taddei, K., Brown, B. M., Benzinger, T., Masters, C., Snowden, S. G., Wenk, M. R., Bateman, R. J., Morris, J. C. & Martins, R. N., Feb 2 2016, In: Journal of Alzheimer's Disease. 50, 3, p. 887-894 8 p.

    Research output: Contribution to journal › Article › peer-review

    32 Scopus citations

  • Post Hoc Analyses of ApoE Genotype-Defined Subgroups in Clinical Trials

    Kennedy, R. E., Cutter, G. R., Wang, G. & Schneider, L. S., Feb 22 2016, In: Journal of Alzheimer's Disease. 50, 4, p. 1205-1215 11 p.

    Research output: Contribution to journal › Article › peer-review

    6 Scopus citations

  • Prospective changes in global DNA methylation and cancer incidence and mortality

    Joyce, B. T., Gao, T., Zheng, Y., Liu, L., Zhang, W., Dai, Q., Shrubsole, M. J., Hibler, E. A., Cristofanilli, M., Zhang, H., Yang, H., Vokonas, P., Cantone, L., Schwartz, J., Baccarelli, A. & Hou, L., Aug 9 2016, In: British Journal of Cancer. 115, 4, p. 465-472 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    31 Scopus citations

  • Quantitative Amyloid imaging in autosomal Dominant Alzheimer's disease: Results from the DIAN study group

    Su, Y., Blazey, T. M., Owen, C. J., Christensen, J. J., Friedrichsen, K., Joseph-Mathurin, N., Wang, Q., Hornbeck, R. C., Ances, B. M., Snyder, A. Z., Cash, L. A., Koeppe, R. A., Klunk, W. E., Galasko, D., Brickman, A. M., McDade, E., Ringman, J. M., Thompson, P. M., Saykin, A. J., Ghetti, B., & 16 othersSperling, R. A., Johnson, K. A., Salloway, S. P., Schofield, P. R., Masters, C. L., Villemagne, V. L., Fox, N. C., Förster, S., Chen, K., Reiman, E. M., Xiong, C., Marcus, D. S., Weiner, M. W., Morris, J. C., Bateman, R. J. & Benzinger, T. L. S., Mar 2016, In: PloS one. 11, 3, e0152082.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    31 Scopus citations

  • Quantitative computed tomography classification of lung nodules: initial comparison of 2- and 3-dimensional analysis

    Gierada, D. S., Politte, D. G., Zheng, J., Schechtman, K. B., Whiting, B. R., Smith, K. E., Crabtree, T., Kreisel, D., Krupnick, A. S., Patterson, G. A., Puri, V. & Meyers, B. F., Jul 1 2016, In: Journal of computer assisted tomography. 40, 4, p. 589-595 7 p.

    Research output: Contribution to journal › Article › peer-review

    7 Scopus citations

  • Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans

    Olfson, E., Saccone, N. L., Johnson, E. O., Chen, L. S., Culverhouse, R., Doheny, K., Foltz, S. M., Fox, L., Gogarten, S. M., Hartz, S., Hetrick, K., Laurie, C. C., Marosy, B., Amin, N., Arnett, D., Barr, R. G., Bartz, T. M., Bertelsen, S., Borecki, I. B., Brown, M. R., & 33 othersChasman, D. I., Van Duijn, C. M., Feitosa, M. F., Fox, E. R., Franceschini, N., Franco, O. H., Grove, M. L., Guo, X., Hofman, A., Kardia, S. L. R., Morrison, A. C., Musani, S. K., Psaty, B. M., Rao, D. C., Reiner, A. P., Rice, K., Ridker, P. M., Rose, L. M., Schick, U. M., Schwander, K., Uitterlinden, A. G., Vojinovic, D., Wang, J. C., Ware, E. B., Wilson, G., Yao, J., Zhao, W., Breslau, N., Hatsukami, D., Stitzel, J. A., Rice, J., Goate, A. & Bierut, L. J., May 1 2016, In: Molecular Psychiatry. 21, 5, p. 601-607 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    25 Scopus citations

  • 'RE:fine drugs': an interactive dashboard to access drug repurposing opportunities

    Moosavinasab, S., Patterson, J., Strouse, R., Rastegar-Mojarad, M., Regan, K., Payne, P. R. O., Huang, Y. & Lin, S. M., 2016, In: Database : the journal of biological databases and curation. 2016

    Research output: Contribution to journal › Article › peer-review

    Open Access
    40 Scopus citations

  • Relationship between symptom change, relapse activity and disability progression in multiple sclerosis

    Liu, Y., Morgan, C., Hornung, L., Tyry, T., Salter, A. R., Agashivala, N., Belletti, D. A., Kim, E., Fox, R. J., Cofield, S. S. & Cutter, G. R., Mar 15 2016, In: Journal of the Neurological Sciences. 362, p. 121-126 6 p.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • Rethinking the role and impact of health information technology: Informatics as an interventional discipline

    Payne, P. R. O., Lussier, Y., Foraker, R. E. & Embi, P. J., 2016, In: BMC Medical Informatics and Decision Making. 16, 1, 40.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations

  • Risk Factors for Incident Hospitalized Heart Failure with Preserved Versus Reduced Ejection Fraction in a Multiracial Cohort of Postmenopausal Women

    Eaton, C. B., Pettinger, M., Rossouw, J., Martin, L. W., Foraker, R., Quddus, A., Liu, S., Wampler, N. S., Hank Wu, W. C., Manson, J. E., Margolis, K., Johnson, K. C., Allison, M., Corbie-Smith, G., Rosamond, W., Breathett, K. & Klein, L., Oct 1 2016, In: Circulation: Heart Failure. 9, 10, e002883.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    115 Scopus citations

  • Segmentation of gliomas in pre-operative and post-operative multimodal magnetic resonance imaging volumes based on a hybrid generative-discriminative framework

    Zeng, K., Bakas, S., Sotiras, A., Akbari, H., Rozycki, M., Rathore, S., Pati, S. & Davatzikos, C., 2016, Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - Second International Workshop, BrainLes 2016, with the Challenges on BRATS, ISLES and mTOP 2016 Held in Conjunction with MICCAI 2016, Revised Selected Papers. Menze, B., Reyes, M., Crimi, A., Maier, O., Winzeck, S. & Handels, H. (eds.). Springer Verlag, p. 184-194 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10154 LNCS).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

    19 Scopus citations

  • Simultaneous paralogue knockout using a CRISPR-concatemer in mouse small intestinal organoids

    Andersson-Rolf, A., Merenda, A., Mustata, R. C., Li, T., Dietmann, S. & Koo, B. K., Dec 15 2016, In: Developmental Biology. 420, 2, p. 271-277 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    17 Scopus citations

  • Specification and epigenetic programming of the human germ line

    Tang, W. W. C., Kobayashi, T., Irie, N., Dietmann, S. & Surani, M. A., Oct 1 2016, In: Nature Reviews Genetics. 17, 10, p. 585-600 16 p.

    Research output: Contribution to journal › Review article › peer-review

    256 Scopus citations

  • Stem cell function and stress response are controlled by protein synthesis

    Blanco, S., Bandiera, R., Popis, M., Hussain, S., Lombard, P., Aleksic, J., Sajini, A., Tanna, H., Cortés-Garrido, R., Gkatza, N., Dietmann, S. & Frye, M., Jun 15 2016, In: Nature. 534, 7607, p. 335-340 6 p.

    Research output: Contribution to journal › Article › peer-review

    248 Scopus citations

  • Structured outlier detection in neuroimaging studies with minimal convex polytopes

    Varol, E., Sotiras, A. & Davatzikos, C., 2016, Medical Image Computing and Computer-Assisted Intervention - MICCAI 2016 - 19th International Conference, Proceedings. Ourselin, S., Joskowicz, L., Sabuncu, M. R., Wells, W. & Unal, G. (eds.). Springer Verlag, p. 300-307 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 9900 LNCS).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

    1 Scopus citations