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  • 2012

    A phase II study of the survivin suppressant YM155 in patients with refractory diffuse large B-cell lymphoma

    Cheson, B. D., Bartlett, N. L., Vose, J. M., Lopez-Hernandez, A., Seiz, A. L., Keating, A. T. & Shamsili, S., Jun 15 2012, In: Cancer. 118, 12, p. 3128-3134 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    102 Scopus citations

  • A phase i study of subcutaneously administered aflibercept (VEGF trap) in a new formulation in patients with advanced solid tumors

    Wang-Gillam, A., Tew, W. P., Rothenberg, M. L., Dupont, J., Cooper, W., Sternas, L., Buzenet, G., Sosman, J. A., Spriggs, D. R. & Lockhart, A. C., Oct 2012, In: Investigational New Drugs. 30, 5, p. 1958-1961 4 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • A phase I weekly dosing study of brentuximab vedotin in patients with relapsed/refractory CD30-positive hematologic malignancies

    Fanale, M. A., Forero-Torres, A., Rosenblatt, J. D., Advani, R. H., Franklin, A. R., Kennedy, D. A., Han, T. H., Sievers, E. L. & Bartlett, N. L., Jan 1 2012, In: Clinical Cancer Research. 18, 1, p. 248-255 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    196 Scopus citations

  • A Randomized, Controlled Trial of Panax quinquefolius Extract (CVT-E002) to Reduce Respiratory Infection in Patients With Chronic Lymphocytic Leukemia

    High, K. P., Case, D., Hurd, D., Powell, B., Lesser, G., Falsey, A. R., Siegel, R., Metzner-Sadurski, J., Krauss, J. C., Chinnasami, B., Sanders, G., Rousey, S. & Shaw, E. G., Sep 2012, In: Journal of Supportive Oncology. 10, 5, p. 195-201 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Scopus citations

  • ARN-509: A novel antiandrogen for prostate cancer treatment

    Clegg, N. J., Wongvipat, J., Joseph, J. D., Tran, C., Ouk, S., Dilhas, A., Chen, Y., Grillot, K., Bischoff, E. D., Cai, L., Aparicio, A., Dorow, S., Arora, V., Shao, G., Qian, J., Zhao, H., Yang, G., Cao, C., Sensintaffar, J. & Wasielewska, T. & 15 others, Herbert, M. R., Bonnefous, C., Darimont, B., Scher, H. I., Smith-Jones, P., Klang, M., Smith, N. D., De Stanchina, E., Wu, N., Ouerfelli, O., Rix, P. J., Heyman, R. A., Jung, M. E., Sawyers, C. L. & Hager, J. H., Mar 15 2012, In: Cancer research. 72, 6, p. 1494-1503 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    595 Scopus citations

  • A roundup of articles published in recent months.

    Subramanian, J., Waqar, S., Morgensztern, D. & Govindan, R., Mar 2012, In: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 7, 3, p. 626-628 3 p.

    Research output: Contribution to journal › Article › peer-review

  • Association between BRCA1 and BRCA2 Mutations and Survival in Women with Invasive Epithelial Ovarian Cancer

    Bolton, K. L., Chenevix-Trench, G., Goh, C., Sadetzki, S., Ramus, S. J., Karlan, B. Y., Lambrechts, D., Despierre, E., Barrowdale, D., McGuffog, L., Healey, S., Easton, D. F., Sinilnikova, O., Benítez, J., García, M. J., Neuhausen, S., Gail, M. H., Hartge, P., Peock, S. & Frost, D. & 55 others, Evans, D. G., Eeles, R., Godwin, A. K., Daly, M. B., Kwong, A., Ma, E. S. K., Lázaro, C., Blanco, I., Montagna, M., D'Andrea, E., Nicoletto, M. O., Johnatty, S. E., Kjær, S. K., Jensen, A., Høgdall, E., Goode, E. L., Fridley, B. L., Loud, J. T., Greene, M. H., Mai, P. L., Chetrit, A., Lubin, F., Hirsh-Yechezkel, G., Glendon, G., Andrulis, I. L., Toland, A. E., Senter, L., Gore, M. E., Gourley, C., Michie, C. O., Song, H., Tyrer, J., Whittemore, A. S., McGuire, V., Sieh, W., Kristoffersson, U., Olsson, H., Borg, Å., Levine, D. A., Steele, L., Beattie, M. S., Chan, S., Nussbaum, R. L., Moysich, K. B., Gross, J., Cass, I., Walsh, C., Li, A. J., Leuchter, R., Gordon, O., Garcia-Closas, M., Gayther, S. A., Chanock, S. J., Antoniou, A. C. & Pharoah, P. D. P., Jan 25 2012, In: JAMA. 307, 4, p. 382-390 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    565 Scopus citations

  • Association of age at diagnosis and genetic mutations in patients with neuroblastoma

    Cheung, N. K. V., Zhang, J., Lu, C., Parker, M., Bahrami, A., Tickoo, S. K., Heguy, A., Pappo, A. S., Federico, S., Dalton, J., Cheung, I. Y., Ding, L., Fulton, R., Wang, J., Chen, X., Becksfort, J., Wu, J., Billups, C. A., Ellison, D. & Mardis, E. R. & 3 others, Wilson, R. K., Downing, J. R. & Dyer, M. A., Mar 14 2012, In: JAMA. 307, 10, p. 1062-1071 10 p.

    Research output: Contribution to journal › Article › peer-review

    380 Scopus citations

  • Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells

    Young, M. A., Larson, D. E., Sun, C. W., George, D. R., Ding, L., Miller, C. A., Lin, L., Pawlik, K. M., Chen, K., Fan, X., Schmidt, H., Kalicki-Veizer, J., Cook, L. L., Swift, G. W., Demeter, R. T., Wendl, M. C., Sands, M. S., Mardis, E. R., Wilson, R. K. & Townes, T. M. & 1 others, Ley, T. J., May 4 2012, In: Cell Stem Cell. 10, 5, p. 570-582 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    170 Scopus citations

  • Battle over CCL2 for control of the metastatic niche: Neutrophils versus monocytes

    Mitchem, J. B. & DeNardo, D. G., Jul 19 2012, In: Breast Cancer Research. 14, 4, 315.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • Bendamustine for treatment of chronic lymphocytic leukemia

    Chang, J. E. & Kahl, B. S., Jul 2012, In: Expert Opinion on Pharmacotherapy. 13, 10, p. 1495-1505 11 p.

    Research output: Contribution to journal › Article › peer-review

    13 Scopus citations

  • Bexarotene is active against subcutaneous panniculitis-like T-cell lymphoma in adult and pediatric populations

    Mehta, N., Wayne, A. S., Kim, Y. H., Hale, G. A., Alvarado, C. S., Myskowski, P., Jaffe, E. S., Busam, K. J., Pulitzer, M., Zwerner, J. & Horwitz, S., Feb 2012, In: Clinical Lymphoma, Myeloma and Leukemia. 12, 1, p. 20-25 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    74 Scopus citations

  • Biomarker-driven trial in metastatic pancreas cancer: Feasibility in a multicenter study of saracatinib, an oral Src inhibitor, in previously treated pancreatic cancer

    Arcaroli, J., Quackenbush, K., Dasari, A., Powell, R., McManus, M., Tan, A. C., Foster, N. R., Picus, J., Wright, J., Nallapareddy, S., Erlichman, C., Hidalgo, M. & Messersmith, W. A., Oct 2012, In: Cancer medicine. 1, 2, p. 207-217 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    13 Scopus citations

  • Bisphosphonates and pathologic complete response to taxane- And anthracycline-based neoadjuvant chemotherapy in patients with breast cancer

    Chavez-MacGregor, M., Brown, E., Lei, X., Litton, J., Meric-Bernstam, F., Mittendorf, E., Hernandez, L., Valero, V., Hortobagyi, G. N. & Gonzalez-Angulo, A. M., Jan 15 2012, In: Cancer. 118, 2, p. 326-332 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations

  • BLM helicase facilitates RNA polymerase I-mediated ribosomal RNA transcription

    Grierson, P. M., Lillard, K., Behbehani, G. K., Combs, K. A., Bhattacharyya, S., Acharya, S. & Groden, J., Mar 2012, In: Human molecular genetics. 21, 5, p. 1172-1183 12 p., ddr545.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    44 Scopus citations

  • Bone marrow stromal cells modulate mouse ent1 activity and protect leukemia cells from cytarabine induced apoptosis

    Macanas-Pirard, P., Leisewitz, A., Broekhuizen, R., Cautivo, K., Barriga, F. M., Leisewitz, F., Gidi, V., Riquelme, E., Montecinos, V. P., Swett, P., Besa, P., Ramirez, P., Ocqueteau, M., Kalergis, A. M., Holt, M., Rettig, M., DiPersio, J. F. & Nervi, B., May 22 2012, In: PloS one. 7, 5, e37203.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    31 Scopus citations

  • Bone marrow transplantation alters the tremor phenotype in the murine model of Globoid-cell Leukodystrophy

    Reddy, A. S., Wozniak, D., Farber, N. B., Dearborn, J., Fowler, S. C. & Sands, M. S., Jan 19 2012, In: Journal of Clinical Medicine. 1, 1, p. 1-14 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • Bone marrow transplantation increases efficacy of central nervous system-directed enzyme replacement therapy in the murine model of globoid cell leukodystrophy

    Qin, E. Y., Hawkins-Salsbury, J. A., Jiang, X., Reddy, A. S., Farber, N. B., Ory, D. S. & Sands, M. S., Sep 2012, In: Molecular genetics and metabolism. 107, 1-2, p. 186-196 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    45 Scopus citations

  • Bortezomib-induced thrombotic thrombocytopaenic purpura

    Mehta, N., Saxena, A. & Niesvizky, R., 2012, In: BMJ Case Reports.

    Research output: Contribution to journal › Article › peer-review

    25 Scopus citations

  • Both XPA and DNA polymerase eta are necessary for the repair of doxorubicin-induced DNA lesions

    Moraes, M. C. S., de Andrade, A. Q., Carvalho, H., Guecheva, T., Agnoletto, M. H., Henriques, J. A. P., Sarasin, A., Stary, A., Saffi, J. & Menck, C. F. M., Jan 1 2012, In: Cancer Letters. 314, 1, p. 108-118 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    28 Scopus citations

  • Breakfusion: Targeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data

    Chen, K., Wallis, J. W., Kandoth, C., Kalicki-veizer, J. M., Mungall, K. L., Mungall, A. J., Jones, S. J., Marra, M. A., Ley, T. J., Mardis, E. R., Wilson, R. K., Weinstein, J. N. & Ding, L., Jul 2012, In: Bioinformatics. 28, 14, p. 1923-1924 2 p., bts272.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    48 Scopus citations

  • Breast cancer cell targeting by prenylation inhibitors elucidated in living animals with a bioluminescence reporter

    Chinault, S. L., Prior, J. L., Kaltenbronn, K. M., Penly, A., Weilbaecher, K. N., Piwnica-Worms, D. & Blumer, K. J., Aug 1 2012, In: Clinical Cancer Research. 18, 15, p. 4136-4144 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • Brentuximab vedotin (SGN-35) in patients with relapsed or refractory systemic anaplastic large-cell lymphoma: Results of a phase II study

    Pro, B., Advani, R., Brice, P., Bartlett, N. L., Rosenblatt, J. D., Illidge, T., Matous, J., Ramchandren, R., Fanale, M., Connors, J. M., Yang, Y., Sievers, E. L., Kennedy, D. A. & Shustov, A., Jun 20 2012, In: Journal of Clinical Oncology. 30, 18, p. 2190-2196 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    896 Scopus citations

  • Brentuximab vedotin in transplant-naïve patients with relapsed or refractory Hodgkin lymphoma: Analysis of two phase I studies

    Forero-Torres, A., Fanale, M., Advani, R., Bartlett, N. L., Rosenblatt, J. D., Kennedy, D. A. & Younes, A., Aug 2012, In: Oncologist. 17, 8, p. 1073-1080 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    40 Scopus citations

  • Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

    Matsushita, H., Vesely, M. D., Koboldt, D. C., Rickert, C. G., Uppaluri, R., Magrini, V. J., Arthur, C. D., White, J. M., Chen, Y. S., Shea, L. K., Hundal, J., Wendl, M. C., Demeter, R., Wylie, T., Allison, J. P., Smyth, M. J., Old, L. J., Mardis, E. R. & Schreiber, R. D., Feb 16 2012, In: Nature. 482, 7385, p. 400-404 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1048 Scopus citations

  • Carfilzomib in multiple myeloma

    Vij, R., Sep 1 2012, In: Clinical Advances in Hematology and Oncology. 10, 9, p. 591-593 3 p.

    Research output: Contribution to journal › Article › peer-review

    2 Scopus citations

  • Cathepsin K-Cre causes unexpected germline deletion of genes in mice

    Winkeler, C. L., Kladney, R. D., Maggi, L. B. & Weber, J. D., Jul 31 2012, In: PloS one. 7, 7, e42005.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    26 Scopus citations

  • Classifying Cytogenetics in Patients with Acute Myelogenous Leukemia in Complete Remission Undergoing Allogeneic Transplantation: A Center forInternational Blood and Marrow Transplant Research Study

    Armand, P., Kim, H. T., Zhang, M. J., Perez, W. S., Dal Cin, P. S., Klumpp, T. R., Waller, E. K., Litzow, M. R., Liesveld, J. L., Lazarus, H. M., Artz, A. S., Gupta, V., Savani, B. N., McCarthy, P. L., Cahn, J. Y., Schouten, H. C., Finke, J., Ball, E. D., Aljurf, M. D. & Cutler, C. S. & 24 others, Rowe, J. M., Antin, J. H., Isola, L. M., Di Bartolomeo, P., Camitta, B. M., Miller, A. M., Cairo, M. S., Stockerl-Goldstein, K., Sierra, J., Savoie, M. L., Halter, J., Stiff, P. J., Nabhan, C., Jakubowski, A. A., Bunjes, D. W., Petersdorf, E. W., Devine, S. M., Maziarz, R. T., Bornhauser, M., Lewis, V. A., Marks, D. I., Bredeson, C. N., Soiffer, R. J. & Weisdorf, D. J., Feb 2012, In: Biology of Blood and Marrow Transplantation. 18, 2, p. 280-288 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    76 Scopus citations

  • Clinical cancer advances 2011: Annual report on progress against cancer from the American Society of Clinical Oncology

    Vogelzang, N. J., Benowitz, S. I., Adams, S., Aghajanian, C., Chang, S. M., Dreyer, Z. A. E., Janne, P. A., Ko, A. H., Masters, G. A., Odenike, O., Patel, J. D., Roth, B. J., Samlowski, W. E., Seidman, A. D., Tap, W. D., Temel, J. S., Von Roenn, J. H. & Kris, M. G., Jan 1 2012, In: Journal of Clinical Oncology. 30, 1, p. 88-109 22 p.

    Research output: Contribution to journal › Article › peer-review

    91 Scopus citations

  • Clinical roundtable monograph: Recent advances in taxanes for the first-line treatment of advanced non-small cell lung cancer.

    Socinski, M. A., Govindan, R. & Spigel, D., Oct 2012, In: Clinical advances in hematology & oncology : H&O. 10, 10 Suppl 18, p. 1-16 16 p.

    Research output: Contribution to journal › Article › peer-review

    2 Scopus citations

  • Clonal Architecture of Secondary Acute Myeloid Leukemia

    Walter, M. J., Shen, D., Ding, L., Shao, J., Koboldt, D. C., Chen, K., Larson, D. E., McLellan, M. D., Dooling, D., Abbott, R., Fulton, R., Magrini, V., Schmidt, H., Kalicki-Veizer, J., O'Laughlin, M., Fan, X., Grillot, M., Witowski, S., Heath, S. & Frater, J. L. & 9 others, Eades, W., Tomasson, M., Westervelt, P., Dipersio, J. F., Link, D. C., Mardis, E. R., Ley, T. J., Wilson, R. K. & Graubert, T. A., Mar 22 2012, In: New England Journal of Medicine. 366, 12, p. 1090-1098 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    670 Scopus citations

  • Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

    Ding, L., Ley, T. J., Larson, D. E., Miller, C. A., Koboldt, D. C., Welch, J. S., Ritchey, J. K., Young, M. A., Lamprecht, T., McLellan, M. D., McMichael, J. F., Wallis, J. W., Lu, C., Shen, D., Harris, C. C., Dooling, D. J., Fulton, R. S., Fulton, L. L., Chen, K. & Schmidt, H. & 19 others, Kalicki-Veizer, J., Magrini, V. J., Cook, L., McGrath, S. D., Vickery, T. L., Wendl, M. C., Heath, S., Watson, M. A., Link, D. C., Tomasson, M. H., Shannon, W. D., Payton, J. E., Kulkarni, S., Westervelt, P., Walter, M. J., Graubert, T. A., Mardis, E. R., Wilson, R. K. & Dipersio, J. F., Jan 26 2012, In: Nature. 481, 7382, p. 506-510 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1683 Scopus citations

  • Combination small molecule PPT1 mimetic and CNS-directed gene therapy as a treatment for infantile neuronal ceroid lipofuscinosis

    Roberts, M. S., Macauley, S. L., Wong, A. M., Yilmas, D., Hohm, S., Cooper, J. D. & Sands, M. S., Sep 2012, In: Journal of Inherited Metabolic Disease. 35, 5, p. 847-857 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    39 Scopus citations

  • Comparative effectiveness of cisplatin-based and carboplatin-based chemotherapy for treatment of advanced urothelial carcinoma

    Galsky, M. D., Chen, G. J., Oh, W. K., Bellmunt, J., Roth, B. J., Petrioli, R., Dogliotti, L., Dreicer, R. & Sonpavde, G., Feb 2012, In: Annals of Oncology. 23, 2, p. 406-410 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    249 Scopus citations

  • Complex reorganization and predominant non-homologous repair following chromosomal breakage in karyotypically balanced germline rearrangements and transgenic integration

    Chiang, C., Jacobsen, J. C., Ernst, C., Hanscom, C., Heilbut, A., Blumenthal, I., Mills, R. E., Kirby, A., Lindgren, A. M., Rudiger, S. R., McLaughlan, C. J., Bawden, C. S., Reid, S. J., Faull, R. L. M., Snell, R. G., Hall, I. M., Shen, Y., Ohsumi, T. K., Borowsky, M. L. & Daly, M. J. & 5 others, Lee, C., Morton, C. C., MacDonald, M. E., Gusella, J. F. & Talkowski, M. E., Apr 2012, In: Nature Genetics. 44, 4, p. 390-397 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    211 Scopus citations

  • Comprehensive gene expression profiling and immunohistochemical studies support application of immunophenotypic algorithm for molecular subtype classification in diffuse large B-cell lymphoma: A report from the International DLBCL Rituximab-CHOP Consortium Program Study

    Visco, C., Li, Y., Xu-Monette, Z. Y., Miranda, R. N., Green, T. M., Li, Y., Tzankov, A., Wen, W., Liu, W. M., Kahl, B. S., D'Amore, E. S. G., Montes-Moreno, S., Dybkær, K., Chiu, A., Tam, W., Orazi, A., Zu, Y., Bhagat, G., Winter, J. N. & Wang, H. Y. & 22 others, O'Neill, S., Dunphy, C. H., Hsi, E. D., Zhao, X. F., Go, R. S., Choi, W. W. L., Zhou, F., Czader, M., Tong, J., Zhao, X., Van Krieken, J. H., Huang, Q., Ai, W., Etzell, J., Ponzoni, M., Ferreri, A. J. M., Piris, M. A., Møller, M. B., Bueso-Ramos, C. E., Medeiros, L. J., Wu, L. & Young, K. H., Sep 2012, In: Leukemia. 26, 9, p. 2103-2113 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    317 Scopus citations

  • Comprehensive genomic characterization of squamous cell lung cancers

    Hammerman, P. S., Voet, D., Lawrence, M. S., Voet, D., Jing, R., Cibulskis, K., Sivachenko, A., Stojanov, P., McKenna, A., Lander, E. S., Gabriel, S., Getz, G., Imielinski, M., Helman, E., Hernandez, B., Pho, N. H., Meyerson, M., Chu, A., Hye-Chun, J. E. & Mungall, A. J. & 316 others, Pleasance, E., Robertson, A. G., Sipahimalani, P., Stoll, D., Balasundaram, M., Birol, I., Butterfield, Y. S. N., Chuah, E., Coope, R. J. N., Corbett, R., Dhalla, N., Guin, R., He, A., Hirst, C., Hirst, M., Holt, R. A., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, K., Nip, K. M., Olshen, A., Schein, J. E., Slobodan, J. R., Tam, A., Thiessen, N., Varhol, R., Zeng, T., Zhao, Y., Jones, S. J. M., Marra, M. A., Saksena, G., Cherniack, A. D., Schumacher, S. E., Tabak, B., Carter, S. L., Nguyen, H., Onofrio, R. C., Crenshaw, A., Ardlie, K., Beroukhim, R., Winckler, W., Protopopov, A., Zhang, J., Hadjipanayis, A., Lee, S., Xi, R., Yang, L., Ren, X., Zhang, H., Shukla, S., Chen, P. C., Haseley, P., Lee, E., Chin, L., Park, P. J., Kucherlapati, R., Socci, N. D., Liang, Y., Schultz, N., Borsu, L., Lash, A. E., Viale, A., Sander, C., Ladanyi, M., Auman, J. T., Hoadley, K. A., Wilkerson, M. D., Shi, Y., Liquori, C., Meng, S., Li, L., Turman, Y. J., Topal, M. D., Tan, D., Waring, S., Buda, E., Walsh, J., Jones, C. D., Mieczkowski, P. A., Singh, D., Wu, J., Gulabani, A., Dolina, P., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Stuart, J., Mose, L. E., Jefferys, S. R., Balu, S., O'Connor, B. D., Chiang, D., Liu, J., Chiang, D. Y., Hayes, D. N., Perou, C. M., Cope, L., Weisenberger, D., Danilova, L., Weisenberger, D. J., Maglinte, D. T., Pan, F., Van Den Berg, D. J., Triche, T., Herman, J. G., Baylin, S. B., Laird, P. W., Noble, M., Gehlenborg, N., DiCara, D., Zhang, J., Wu, C. J., Liu, S. Y., Zou, L., Lin, P., Cho, J., Nazaire, M. D., Robinson, J., Thorvaldsdottir, H., Mesirov, J., Sinha, R., Ciriello, G., Cerami, E., Gross, B., Jacobsen, A., Gao, J., Aksoy, B. A., Weinhold, N., Ramirez, R., Taylor, B. S., Antipin, Y., Reva, B., Mo, Q., Seshan, V., Paik, P. K., Akbani, R., Zhang, N., Broom, B. M., Casasent, T., Unruh, A., Wakefield, C., Cason, R. C., Baggerly, K. A., Weinstein, J. N., Haussler, D., Benz, C. C., Stuart, J. M., Zhu, J., Szeto, C., Scott, G. K., Yau, C., Ng, S., Goldstein, T., Waltman, P., Sokolov, A., Collisson, E., Ellrott, K., Collisson, E. A., Zerbino, D., Ma, S., Craft, B., Du, Y., Cabanski, C., Walter, V., Marron, J. S., Liu, Y., Wang, K., Prins, J. F., Creighton, C. J., Zhang, Y., Travis, W. D., Rekhtman, N., Yi, J., Aubry, M. C., Cheney, R., Dacic, S., Flieder, D., Funkhouser, W., Illei, P., Myers, J., Tsao, M. S., Penny, R., Mallery, D., Shelton, T., Hatfield, M., Morris, S., Yena, P., Shelton, C., Sherman, M., Paulauskis, J., Govindan, R., Azodo, I., Beer, D., Bose, R., Byers, L. A., Carbone, D., Chang, L. W., Chun, E., Ding, L., Heymach, J., Ida, C., Johnson, B., Jurisica, I., Kaufman, J., Kosari, F., Kwiatkowski, D., Maher, C. A., Pao, W., Peifer, M., Robertson, G., Rusch, V., Siegfried, J., Sougnez, C., Thomas, R. K., Tomaszek, S., Vaske, C., Wheeler, D., Wigle, D. A., Wilks, C., Zhang, J. J., Jensen, M. A., Sfeir, R., Kahn, A. B., Chu, A. L., Kothiyal, P., Wang, Z., Snyder, E. E., Pontius, J., Pihl, T. D., Backus, M., Walton, J., Baboud, J., Berton, D. L., Nicholls, M. C., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P. A., Alonso, S., Sanbhadti, R. N., Barletta, S. P., Greene, J. M., Pot, D. A., Bandarchi-Chamkhaleh, B., Boyd, J., Weaver, J., Azodo, I. A., Tomaszek, S. C., Yang, P., Brock, M. V., Rogers, K., Rutledge, M., Brown, T., Lee, B., Shin, J., Trusty, D., Dhir, R., Siegfried, J. M., Potapova, O., Fedosenko, K. V., Zakowski, M., Nemirovich-Danchenko, E., Iacocca, M. V., Brown, J., Rabeno, B., Czerwinski, C., Petrelli, N., Fan, Z., Todaro, N., Eckman, J., Rathmell, W. K., Thorne, L. B., Huang, M., Boice, L., Hill, A., Curley, E., Morrison, C., Gaudioso, C., Bartlett, J. M. S., Kodeeswaran, S., Zanke, B., Sekhon, H., David, K., Juhl, H., Le, X. V., Kohl, B., Thorp, R., Tien, N. V., Bang, N. V., Sussman, H., Phu, B. D., Hajek, R., Hung, N. P., Khan, K. Z., Muley, T., Mills Shaw, K. R., Sheth, M., Yang, L., Demchok, J. A., Davidsen, T., Buetow, K., Eley, G., Ferguson, M., Dillon, L. A. L., Schaefer, C., Guyer, M. S., Ozenberger, B. A., Palchik, J. D., Peterson, J., Sofia, H. J., Thomson, E., Johnson, B. E. & Shen, R., Sep 27 2012, In: Nature. 489, 7417, p. 519-525 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    3283 Scopus citations

  • Comprehensive molecular characterization of human colon and rectal cancer

    Muzny, D. M., Bainbridge, M. N., Chang, K., Dinh, H. H., Drummond, J. A., Fowler, G., Kovar, C. L., Lewis, L. R., Morgan, M. B., Newsham, I. F., Reid, J. G., Santibanez, J., Shinbrot, E., Trevino, L. R., Wu, Y. Q., Wang, M., Gunaratne, P., Donehower, L. A., Creighton, C. J. & Wheeler, D. A. & 293 others, Gibbs, R. A., Lawrence, M. S., Voet, D., Jing, R., Cibulskis, K., Sivachenko, A., Stojanov, P., McKenna, A., Lander, E. S., Gabriel, S., Ding, L., Fulton, R. S., Koboldt, D. C., Wylie, T., Walker, J., Dooling, D. J., Fulton, L., Delehaunty, K. D., Fronick, C. C., Demeter, R., Mardis, E. R., Wilson, R. K., Chu, A., Chun, H. J. E., Mungall, A. J., Pleasance, E., Gordon Robertson, A., Stoll, D., Balasundaram, M., Birol, I., Butterfield, Y. S. N., Chuah, E., Coope, R. J. N., Dhalla, N., Guin, R., Hirst, C., Hirst, M., Holt, R. A., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Schein, J. E., Slobodan, J. R., Tam, A., Thiessen, N., Varhol, R., Zeng, T., Zhao, Y., Jones, S. J. M., Marra, M. A., Bass, A. J., Ramos, A. H., Saksena, G., Cherniack, A. D., Schumacher, S. E., Tabak, B., Carter, S. L., Pho, N. H., Nguyen, H., Onofrio, R. C., Crenshaw, A., Ardlie, K., Beroukhim, R., Winckler, W., Meyerson, M., Protopopov, A., Hadjipanayis, A., Lee, E., Xi, R., Yang, L., Ren, X., Sathiamoorthy, N., Chen, P. C., Haseley, P., Xiao, Y., Lee, S., Seidman, J., Chin, L., Park, P. J., Kucherlapati, R., Todd Auman, J., Hoadley, K. A., Du, Y., Wilkerson, M. D., Shi, Y., Liquori, C., Meng, S., Li, L., Turman, Y. J., Topal, M. D., Tan, D., Waring, S., Buda, E., Walsh, J., Jones, C. D., Mieczkowski, P. A., Singh, D., Wu, J., Gulabani, A., Dolina, P., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M., Mose, L. E., Jefferys, S. R., Balu, S., O'Connor, B. D., Prins, J. F., Chiang, D. Y., Neil Hayes, D., Perou, C. M., Hinoue, T., Weisenberger, D. J., Maglinte, D. T., Pan, F., Berman, B. P., Van Den Berg, D. J., Shen, H., Triche, T., Baylin, S. B., Laird, P. W., Getz, G., Noble, M., Voat, D., Gehlenborg, N., Dicara, D., Zhang, J., Zhang, H., Wu, C. J., Liu, S. Y., Shukla, S., Zhou, L., Lin, P., Park, R. W., Nazaire, M. D., Robinson, J., Thorvaldsdottir, H., Mesirov, J., Thorsson, V., Reynolds, S. M., Bernard, B., Kreisberg, R., Lin, J., Iype, L., Bressler, R., Erkkilä, T., Gundapuneni, M., Liu, Y., Norberg, A., Robinson, T., Yang, D., Zhang, W., Shmulevich, I., De Ronde, J. J., Schultz, N., Cerami, E., Ciriello, G., Goldberg, A. P., Gross, B., Jacobsen, A., Gao, J., Kaczkowski, B., Sinha, R., Arman Aksoy, B., Antipin, Y., Reva, B., Shen, R., Taylor, B. S., Ladanyi, M., Sander, C., Akbani, R., Zhang, N., Broom, B. M., Casasent, T., Unruh, A., Wakefield, C., Hamilton, S. R., Craig Cason, R., Baggerly, K. A., Weinstein, J. N., Haussler, D., Benz, C. C., Stuart, J. M., Benz, S. C., Zachary Sanborn, J., Vaske, C. J., Zhu, J., Szeto, C., Scott, G. K., Yau, C., Ng, S., Goldstein, T., Ellrott, K., Collisson, E., Cozen, A. E., Zerbino, D., Wilks, C., Craft, B., Spellman, P., Penny, R., Shelton, T., Hatfield, M., Morris, S., Yena, P., Shelton, C., Sherman, M., Paulauskis, J., Gastier-Foster, J. M., Bowen, J., Ramirez, N. C., Black, A., Pyatt, R., Wise, L., White, P., Bertagnolli, M., Brown, J., Chan, T. A., Chu, G. C., Czerwinski, C., Denstman, F., Dhir, R., Dörner, A., Fuchs, C. S., Guillem, J. G., Iacocca, M., Juhl, H., Kaufman, A., Iii, B. K., Van Le, X., Mariano, M. C., Medina, E. N., Meyers, M., Nash, G. M., Paty, P. B., Petrelli, N., Rabeno, B., Richards, W. G., Solit, D., Swanson, P., Temple, L., Tepper, J. E., Thorp, R., Vakiani, E., Weiser, M. R., Willis, J. E., Witkin, G., Zeng, Z., Zinner, M. J., Zornig, C., Jensen, M. A., Sfeir, R., Kahn, A. B., Chu, A. L., Kothiyal, P., Wang, Z., Snyder, E. E., Pontius, J., Pihl, T. D., Ayala, B., Backus, M., Walton, J., Whitmore, J., Baboud, J., Berton, D. L., Nicholls, M. C., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P. A., Alonso, S., Sanbhadti, R. N., Barletta, S. P., Greene, J. M., Pot, D. A., Shaw, K. R. M., Dillon, L. A. L., Buetow, K., Davidsen, T., Demchok, J. A., Eley, G., Ferguson, M., Fielding, P., Schaefer, C., Sheth, M., Yang, L., Guyer, M. S., Ozenberger, B. A., Palchik, J. D., Peterson, J., Sofia, H. J. & Thomson., E., Jul 19 2012, In: Nature. 487, 7407, p. 330-337 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    6803 Scopus citations

  • Comprehensive molecular portraits of human breast tumours

    Koboldt, D. C., Fulton, R. S., McLellan, M. D., Schmidt, H., Kalicki-Veizer, J., McMichael, J. F., Fulton, L. L., Dooling, D. J., Ding, L., Mardis, E. R., Wilson, R. K., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chu, A., Chuah, E., Chun, H. J. E. & Coope, R. J. N. & 323 others, Dhalla, N., Guin, R., Hirst, C., Hirst, M., Holt, R. A., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, A. J., Pleasance, E., Robertson, A. G., Schein, J. E., Shafiei, A., Sipahimalani, P., Slobodan, J. R., Stoll, D., Tam, A., Thiessen, N., Varhol, R. J., Wye, N., Zeng, T., Zhao, Y., Birol, I., Jones, S. J. M., Marra, M. A., Cherniack, A. D., Saksena, G., Onofrio, R. C., Pho, N. H., Carter, S. L., Schumacher, S. E., Tabak, B., Hernandez, B., Gentry, J., Nguyen, H., Crenshaw, A., Ardlie, K., Beroukhim, R., Winckler, W., Getz, G., Gabriel, S. B., Meyerson, M., Chin, L., Kucherlapati, R., Hoadley, K. A., Auman, J. T., Fan, C., Turman, Y. J., Shi, Y., Li, L., Topal, M. D., He, X., Chao, H. H., Prat, A., Silva, G. O., Iglesia, M. D., Zhao, W., Usary, J., Berg, J. S., Adams, M., Booker, J., Wu, J., Gulabani, A., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Mose, L. E., Jefferys, S. R., Balu, S., Parker, J. S., Hayes, D. N., Perou, C. M., Malik, S., Mahurkar, S., Shen, H., Weisenberger, D. J., Triche, T., Lai, P. H., Bootwalla, M. S., Maglinte, D. T., Berman, B. P., Van Den Berg, D. J., Baylin, S. B., Laird, P. W., Creighton, C. J., Donehower, L. A., Noble, M., Voet, D., Gehlenborg, N., Di Cara, D., Zhang, J., Zhang, H., Wu, C. J., Yingchun Liu, S., Lawrence, M. S., Zou, L., Sivachenko, A., Lin, P., Stojanov, P., Jing, R., Cho, J., Sinha, R., Park, R. W., Nazaire, M. D., Robinson, J., Thorvaldsdottir, H., Mesirov, J., Park, P. J., Reynolds, S., Kreisberg, R. B., Bernard, B., Bressler, R., Erkkila, T., Lin, J., Thorsson, V., Zhang, W., Shmulevich, I., Ciriello, G., Weinhold, N., Schultz, N., Gao, J., Cerami, E., Gross, B., Jacobsen, A., Sinha, R., Aksoy, B. A., Antipin, Y., Reva, B., Shen, R., Taylor, B. S., Ladanyi, M., Sander, C., Anur, P., Spellman, P. T., Lu, Y., Liu, W., Verhaak, R. R. G., Mills, G. B., Akbani, R., Zhang, N., Broom, B. M., Casasent, T. D., Wakefield, C., Unruh, A. K., Baggerly, K., Coombes, K., Weinstein, J. N., Haussler, D., Benz, C. C., Stuart, J. M., Benz, S. C., Zhu, J., Szeto, C. C., Scott, G. K., Yau, C., Paull, E. O., Carlin, D., Wong, C., Sokolov, A., Thusberg, J., Mooney, S., Ng, S., Goldstein, T. C., Ellrott, K., Grifford, M., Wilks, C., Ma, S., Craft, B., Yan, C., Hu, Y., Meerzaman, D., Gastier-Foster, J. M., Bowen, J., Ramirez, N. C., Black, A. D., Pyatt, R. E., White, P., Zmuda, E. J., Frick, J., Lichtenberg, T. M., Brookens, R., George, M. M., Gerken, M. A., Harper, H. A., Leraas, K. M., Wise, L. J., Tabler, T. R., McAllister, C., Barr, T., Hart-Kothari, M., Tarvin, K., Saller, C., Sandusky, G., Mitchell, C., Iacocca, M. V., Brown, J., Rabeno, B., Czerwinski, C., Petrelli, N., Dolzhansky, O., Abramov, M., Voronina, O., Potapova, O., Marks, J. R., Suchorska, W. M., Murawa, D., Kycler, W., Ibbs, M., Korski, K., Spychała, A., Murawa, P., Brzeziński, J. J., Perz, H., Łaźniak, R., Teresiak, M., Tatka, H., Leporowska, E., Bogusz-Czerniewicz, M., Malicki, J., Mackiewicz, A., Wiznerowicz, M., Van Le, X., Kohl, B., Viet Tien, N., Thorp, R., Van Bang, N., Sussman, H., Phu, B. D., Hajek, R., Hung, N. P., Phuong, T. V. T., Thang, H. Q., Khan, K. Z., Penny, R., Mallery, D., Curley, E., Shelton, C., Yena, P., Ingle, J. N., Couch, F. J., Lingle, W. L., King, T. A., Gonzalez-Angulo, A. M., Dyer, M. D., Liu, S., Meng, X., Patangan, M., Waldman, F., Stöppler, H., Rathmell, W. K., Thorne, L., Huang, M., Boice, L., Hill, A., Morrison, C., Gaudioso, C., Bshara, W., Daily, K., Egea, S. C., Pegram, M. D., Gomez-Fernandez, C., Dhir, R., Bhargava, R., Brufsky, A., Shriver, C. D., Hooke, J. A., Campbell, J. L., Mural, R. J., Hu, H., Somiari, S., Larson, C., Deyarmin, B., Kvecher, L., Kovatich, A. J., Ellis, M. J., Stricker, T., White, K., Olopade, O., Luo, C., Chen, Y., Bose, R., Chang, L. W., Beck, A. H., Pihl, T., Jensen, M., Sfeir, R., Kahn, A., Chu, A., Kothiyal, P., Wang, Z., Snyder, E., Pontius, J., Ayala, B., Backus, M., Walton, J., Baboud, J., Berton, D., Nicholls, M., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P., Alonso, S., Sanbhadti, R., Barletta, S., Pot, D., Sheth, M., Demchok, J. A., Shaw, K. R. M., Yang, L., Eley, G., Ferguson, M. L., Tarnuzzer, R. W., Zhang, J., Dillon, L. A. L., Buetow, K., Fielding, P., Ozenberger, B. A., Guyer, M. S., Sofia, H. J. & Palchik, J. D., Oct 4 2012, In: Nature. 490, 7418, p. 61-70 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9579 Scopus citations

  • Compromised margins following mastectomy for stage I-III invasive breast cancer

    Yu, J., Mushawah, F. A., Taylor, M. E., Cyr, A. E., Gillanders, W. E., Aft, R. L., Eberlein, T. J., Gao, F. & Margenthaler, J. A., Sep 2012, In: Journal of Surgical Research. 177, 1, p. 102-108 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • Core features of frontotemporal dementia recapitulated in progranulin knockout mice

    Ghoshal, N., Dearborn, J. T., Wozniak, D. F. & Cairns, N. J., Jan 2012, In: Neurobiology of Disease. 45, 1, p. 395-408 14 p.

    Research output: Contribution to journal › Article › peer-review

    92 Scopus citations

  • Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib

    Daemen, A., Wolf, D. M., Korkola, J. E., Griffith, O. L., Frankum, J. R., Brough, R., Jakkula, L. R., Wang, N. J., Natrajan, R., Reis-Filho, J. S., Lord, C. J., Ashworth, A., Spellman, P. T., Gray, J. W. & Van'T Veer, L. J., Sep 2012, In: Breast Cancer Research and Treatment. 135, 2, p. 505-517 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    67 Scopus citations

  • Cytokine activation induces human memory-like NK cells

    Romee, R., Schneider, S. E., Leong, J. W., Chase, J. M., Keppel, C. R., Sullivan, R. P., Cooper, M. A. & Fehniger, T. A., Dec 6 2012, In: Blood. 120, 24, p. 4751-4760 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    508 Scopus citations

  • Decision making in advanced breast cancer

    Naughton, M., Aug 23 2012, In: Journal of Managed Care Medicine. 15, 2, p. 5-8 4 p.

    Research output: Contribution to journal › Article › peer-review

  • Defining the DNA uptake specificity of naturally competent Haemophilus influenzae cells

    Mell, J. C., Hall, I. M. & Redfield, R. J., Sep 2012, In: Nucleic acids research. 40, 17, p. 8536-8549 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    41 Scopus citations

  • Delayed repeated intraperitoneal chemotherapy after cytoreductive surgery for colorectal and appendiceal carcinomatosis

    Fajardo, A. D., Tan, B., Reddy, R. & Fleshman, J., Oct 2012, In: Diseases of the Colon and Rectum. 55, 10, p. 1044-1052 9 p.

    Research output: Contribution to journal › Article › peer-review

    6 Scopus citations

  • Dephosphorylation of HuR protein during alphavirus infection is associated with HuR relocalization to the cytoplasm

    Dickson, A. M., Anderson, J. R., Barnhart, M. D., Sokoloski, K. J., Oko, L., Opyrchal, M., Galanis, E., Wilusz, C. J., Morrison, T. E. & Wilusz, J., Oct 19 2012, In: Journal of Biological Chemistry. 287, 43, p. 36229-36238 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    48 Scopus citations

  • Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors

    Vivanco, I., Ian Robins, H., Rohle, D., Campos, C., Grommes, C., Nghiemphu, P. L., Kubek, S., Oldrini, B., Chheda, M. G., Yannuzzi, N., Tao, H., Zhu, S., Iwanami, A., Kuga, D., Dang, J., Pedraza, A., Brennan, C. W., Heguy, A., Liau, L. M. & Lieberman, F. & 19 others, Alfred Yung, W. K., Gilbert, M. R., Reardon, D. A., Drappatz, J., Wen, P. Y., Lamborn, K. R., Chang, S. M., Prados, M. D., Fine, H. A., Horvath, S., Wu, N., Lassman, A. B., DeAngelis, L. M., Yong, W. H., Kuhn, J. G., Mischel, P. S., Mehta, M. P., Cloughesy, T. F. & Mellinghoff, I. K., May 2012, In: Cancer discovery. 2, 5, p. 458-471 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    282 Scopus citations

  • Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners

    Fraley, S. I., Feng, Y., Giri, A., Longmore, G. D. & Wirtz, D., 2012, In: Nature communications. 3, 719.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    89 Scopus citations

  • Disease recurrence in sentinel node-positive breast cancer patients forgoing axillary lymph node dissection

    Cyr, A., Gao, F., Gillanders, W. E., Aft, R. L., Eberlein, T. J. & Margenthaler, J. A., Oct 2012, In: Annals of Surgical Oncology. 19, 10, p. 3185-3191 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    17 Scopus citations