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  • 2013

    Whole-rat conditional gene knockout via genome editing

    Brown, A. J., Fisher, D. A., Kouranova, E., McCoy, A., Forbes, K., Wu, Y., Henry, R., Ji, D., Chambers, A., Warren, J., Shu, W., Weinstein, E. J. & Cui, X., Jul 2013, In: Nature Methods. 10, 7, p. 638-640 3 p.

    Research output: Contribution to journalArticlepeer-review

    60 Scopus citations
  • X-linked markers in the Duchenne muscular dystrophy gene associated with oral clefts

    Patel, P. J., Beaty, T. H., Ruczinski, I., Murray, J. C., Marazita, M. L., Munger, R. G., Hetmanski, J. B., Wu, T., Murray, T., Rose, M., Redett, R. J., Jin, S. C., Lie, R. T., Wu-Chou, Y. H., Wang, H., Ye, X., Yeow, V., Chong, S., Jee, S. H., Shi, B., & 1 othersScott, A. F., Apr 2013, In: European Journal of Oral Sciences. 121, 2, p. 63-68 6 p.

    Research output: Contribution to journalArticlepeer-review

    10 Scopus citations
  • 2012

    ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry

    Bierut, L. J., Goate, A. M., Breslau, N., Johnson, E. O., Bertelsen, S., Fox, L., Agrawal, A., Bucholz, K. K., Grucza, R., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Porjesz, B., Saccone, N. L., Schuckit, M., Tischfield, J., Wang, J. C., Foroud, T., Rice, J. P., & 1 othersEdenberg, H. J., Apr 2012, In: Molecular Psychiatry. 17, 4, p. 445-450 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    151 Scopus citations
  • Adrenergic-pathway gene variants influence beta-blockerrelated outcomes after acute coronary syndrome in a race-specific manner

    Cresci, S., Dorn, G. W., Jones, P. G., Beitelshees, A. L., Li, A. Y., Lenzini, P. A., Province, M. A., Spertus, J. A. & Lanfear, D. E., Sep 4 2012, In: Journal of the American College of Cardiology. 60, 10, p. 898-907 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    33 Scopus citations
  • A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

    Manning, A. K., Hivert, M. F., Scott, R. A., Grimsby, J. L., Bouatia-Naji, N., Chen, H., Rybin, D., Liu, C. T., Bielak, L. F., Prokopenko, I., Amin, N., Barnes, D., Cadby, G., Hottenga, J. J., Ingelsson, E., Jackson, A. U., Johnson, T., Kanoni, S., Ladenvall, C., Lagou, V., & 196 othersLahti, J., Lecoeur, C., Liu, Y., Martinez-Larrad, M. T., Montasser, M. E., Navarro, P., Perry, J. R. B., Rasmussen-Torvik, L. J., Salo, P., Sattar, N., Shungin, D., Strawbridge, R. J., Tanaka, T., Van Duijn, C. M., An, P., De Andrade, M., Andrews, J. S., Aspelund, T., Atalay, M., Aulchenko, Y., Balkau, B., Bandinelli, S., Beckmann, J. S., Beilby, J. P., Bellis, C., Bergman, R. N., Blangero, J., Boban, M., Boehnke, M., Boerwinkle, E., Bonnycastle, L. L., Boomsma, D. I., Borecki, I. B., Böttcher, Y., Bouchard, C., Brunner, E., Budimir, D., Campbell, H., Carlson, O., Chines, P. S., Clarke, R., Collins, F. S., Corbató-Anchuelo, A., Couper, D., De Faire, U., Dedoussis, G. V., Deloukas, P., Dimitriou, M., Egan, J. M., Eiriksdottir, G., Erdos, M. R., Eriksson, J. G., Eury, E., Ferrucci, L., Ford, I., Forouhi, N. G., Fox, C. S., Franzosi, M. G., Franks, P. W., Frayling, T. M., Froguel, P., Galan, P., De Geus, E., Gigante, B., Glazer, N. L., Goel, A., Groop, L., Gudnason, V., Hallmans, G., Hamsten, A., Hansson, O., Harris, T. B., Hayward, C., Heath, S., Hercberg, S., Hicks, A. A., Hingorani, A., Hofman, A., Hui, J., Hung, J., Jarvelin, M. R., Jhun, M. A., Johnson, P. C. D., Jukema, J. W., Jula, A., Kao, W. H., Kaprio, J., Kardia, S. L. R., Keinanen-Kiukaanniemi, S., Kivimaki, M., Kolcic, I., Kovacs, P., Kumari, M., Kuusisto, J., Kyvik, K. O., Laakso, M., Lakka, T., Lannfelt, L., Mark Lathrop, G., Launer, L. J., Leander, K., Li, G., Lind, L., Lindstrom, J., Lobbens, S., Loos, R. J. F., Luan, JA., Lyssenko, V., Mägi, R., Magnusson, P. K. E., Marmot, M., Meneton, P., Mohlke, K. L., Mooser, V., Morken, M. A., Miljkovic, I., Narisu, N., O'Connell, J., Ong, K. K., Oostra, B. A., Palmer, L. J., Palotie, A., Pankow, J. S., Peden, J. F., Pedersen, N. L., Pehlic, M., Peltonen, L., Penninx, B., Pericic, M., Perola, M., Perusse, L., Peyser, P. A., Polasek, O., Pramstaller, P. P., Province, M. A., Räikkönen, K., Rauramaa, R., Rehnberg, E., Rice, K., Rotter, J. I., Rudan, I., Ruokonen, A., Saaristo, T., Sabater-Lleal, M., Salomaa, V., Savage, D. B., Saxena, R., Schwarz, P., Seedorf, U., Sennblad, B., Serrano-Rios, M., Shuldiner, A. R., Sijbrands, E. J. G., Siscovick, D. S., Smit, J. H., Small, K. S., Smith, N. L., Smith, A. V., Stančáková, A., Stirrups, K., Stumvoll, M., Sun, Y. V., Swift, A. J., Tönjes, A., Tuomilehto, J., Trompet, S., Uitterlinden, A. G., Uusitupa, M., Vikström, M., Vitart, V., Vohl, M. C., Voight, B. F., Vollenweider, P., Waeber, G., Waterworth, D. M., Watkins, H., Wheeler, E., Widen, E., Wild, S. H., Willems, S. M., Willemsen, G., Wilson, J. F., Witteman, J. C. M., Wright, A. F., Yaghootkar, H., Zelenika, D., Zemunik, T., Zgaga, L., Wareham, N. J., McCarthy, M. I., Barroso, I., Watanabe, R. M., Florez, J. C., Dupuis, J., Meigs, J. B. & Langenberg, C., Jun 2012, In: Nature Genetics. 44, 6, p. 659-669 11 p.

    Research output: Contribution to journalArticlepeer-review

    539 Scopus citations
  • A genome-wide association search for type 2 diabetes genes in african americans

    DIAGRAM Consortium, MAGIC Investigators, Anders Hamsten on behalf of Procardis Consortium, DIAGRAM Consortium, GIANT Consortium, Global BPgen Consortium & for the MAGIC investigators, Jan 4 2012, In: PloS one. 7, 1, e29202.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    136 Scopus citations
  • A model of spatially restricted transcription in opposing gradients of activators and repressors

    White, M. A., Parker, D. S., Barolo, S. & Cohen, B. A., 2012, In: Molecular Systems Biology. 8, 614.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    26 Scopus citations
  • A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration

    Bhattacharya, M. R. C., Gerdts, J., Naylor, S. A., Royse, E. X., Ebstein, S. Y., Sasaki, Y., Milbrandt, J. & Diantonio, A., Apr 11 2012, In: Journal of Neuroscience. 32, 15, p. 5054-5061 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    48 Scopus citations
  • An intercellular pathway for glucose transport into mouse oocytes

    Wang, Q., Chi, M. M., Schedl, T. & Moley, K. H., Jun 15 2012, In: American Journal of Physiology - Endocrinology and Metabolism. 302, 12, p. E1511-E1518

    Research output: Contribution to journalArticlepeer-review

    48 Scopus citations
  • An optimized two-finger archive for ZFN-mediated gene targeting

    Gupta, A., Christensen, R. G., Rayla, A. L., Lakshmanan, A., Stormo, G. D. & Wolfe, S. A., Jun 2012, In: Nature Methods. 9, 6, p. 588-590 3 p.

    Research output: Contribution to journalArticlepeer-review

    99 Scopus citations
  • Assembly and Maintenance of Nodes of Ranvier Rely on Distinct Sources of Proteins and Targeting Mechanisms

    Zhang, Y., Bekku, Y., Dzhashiashvili, Y., Armenti, S., Meng, X., Sasaki, Y., Milbrandt, J. & Salzer, J. L., Jan 12 2012, In: Neuron. 73, 1, p. 92-107 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    68 Scopus citations
  • Assessment of Genotype Imputation Performance Using 1000 Genomes in African American Studies

    Hancock, D. B., Levy, J. L., Gaddis, N. C., Bierut, L. J., Saccone, N. L., Page, G. P. & Johnson, E. O., Nov 30 2012, In: PloS one. 7, 11, e50610.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    34 Scopus citations
  • A systematic study of gene expression variation at single-nucleotide resolution reveals widespread regulatory roles for uAUGs

    Yun, Y., Adesanya, T. M. A. & Mitra, R. D., Jun 2012, In: Genome research. 22, 6, p. 1089-1097 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    22 Scopus citations
  • "Calling Cards" for DNA-binding Proteins in mammalian Cells

    Wang, H., Mayhew, D., Chen, X., Johnston, M. & Mitra, R. D., Mar 2012, In: Genetics. 190, 3, p. 941-949 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    39 Scopus citations
  • Candidate pathways for promoting differentiation or quiescence of oligodendrocyte progenitor-like cells in glioma

    Dougherty, J. D., Fomchenko, E. I., Akuffo, A. A., Schmidt, E., Helmy, K. Y., Bazzoli, E., Brennan, C. W., Holland, E. C. & Milosevic, A., Sep 15 2012, In: Cancer research. 72, 18, p. 4856-4868 13 p.

    Research output: Contribution to journalArticlepeer-review

    48 Scopus citations
  • CHRNB3 is more strongly associated with Fagerström Test for Cigarette Dependence-based nicotine dependence than cigarettes per day: Phenotype definition changes genome-wide association studies results

    Rice, J. P., Hartz, S. M., Agrawal, A., Almasy, L., Bennett, S., Breslau, N., Bucholz, K. K., Doheny, K. F., Edenberg, H. J., Goate, A. M., Hesselbrock, V., Howells, W. B., Johnson, E. O., Kramer, J., Krueger, R. F., Kuperman, S., Laurie, C., Manolio, T. A., Neuman, R. J., Nurnberger, J. I., & 7 othersPorjesz, B., Pugh, E., Ramos, E. M., Saccone, N., Saccone, S., Schuckit, M. & Bierut, L. J., Nov 2012, In: Addiction. 107, 11, p. 2019-2028 10 p.

    Research output: Contribution to journalArticlepeer-review

    59 Scopus citations
  • Comparative epigenomic annotation of regulatory DNA

    Xiao, S., Xie, D., Cao, X., Yu, P., Xing, X., Chen, C. C., Musselman, M., Xie, M., West, F. D., Lewin, H. A., Wang, T. & Zhong, S., Jun 8 2012, In: Cell. 149, 6, p. 1381-1392 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    139 Scopus citations
  • Complex effects of nucleotide variants in a mammalian cis-regulatory element

    Kwasnieski, J. C., Mogno, I., Myers, C. A., Corbo, J. C. & Cohen, B. A., Nov 20 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 47, p. 19498-19503 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    152 Scopus citations
  • Conserved motifs and prediction of regulatory modules in caenorhabditis elegans

    Zhao, G., Ihuegbu, N., Lee, M., Schriefer, L., Wang, T. & Stormo, G. D., Apr 2012, In: G3: Genes, Genomes, Genetics. 2, 4, p. 469-481 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations
  • Creation and preliminary characterization of a leptin knockout rat

    Vaira, S., Yang, C., McCoy, A., Keys, K., Xue, S., Weinstein, E. J., Novack, D. V. & Cui, X., Nov 1 2012, In: Endocrinology. 153, 11, p. 5622-5628 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    29 Scopus citations
  • Cyclin-Dependent Kinases Are Regulators and Effectors of Oscillations Driven by a Transcription Factor Network

    Simmons Kovacs, L. A., Mayhew, M. B., Orlando, D. A., Jin, Y., Li, Q., Huang, C., Reed, S. I., Mukherjee, S. & Haase, S. B., Mar 9 2012, In: Molecular cell. 45, 5, p. 669-679 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    48 Scopus citations
  • Detection of rare genomic variants from pooled sequencing using SPLINTER

    Vallania, F., Ramos, E., Cresci, S., Mitra, R. D. & Druley, T. E., Jun 23 2012, In: Journal of Visualized Experiments. 64, p. 1-9 9 p., e3943.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Developmental Plasticity Is Bound by Pluripotency and the Fgf and Wnt Signaling Pathways

    Morris, S. A., Guo, Y. & Zernicka-Goetz, M., Oct 25 2012, In: Cell Reports. 2, 4, p. 756-765 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    67 Scopus citations
  • Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems

    Patel, A., Harker, N., Moreira-Santos, L., Ferreira, M., Alden, K., Timmis, J., Foster, K., Garefalaki, A., Pachnis, P., Andrews, P., Enomoto, H., Milbrandt, J., Pachnis, V., Coles, M. C., Kioussis, D. & Veiga-Fernandes, H., Jul 31 2012, In: Science signaling. 5, 235, ra55.

    Research output: Contribution to journalArticlepeer-review

    49 Scopus citations
  • Dissection of the phenotypic and genotypic associations with nicotinic dependence

    Chen, L. S., Baker, T. B., Grucza, R., Wang, J. C., Johnson, E. O., Breslau, N., Hatsukami, D., Smith, S. S., Saccone, N., Saccone, S., Rice, J. P., Goate, A. M. & Bierut, L. J., Nov 2012, In: Nicotine and Tobacco Research. 14, 4, p. 425-433 9 p.

    Research output: Contribution to journalArticlepeer-review

    39 Scopus citations
  • Dual Leucine Zipper Kinase Is Required for Retrograde Injury Signaling and Axonal Regeneration

    Shin, J. E., Cho, Y., Beirowski, B., Milbrandt, J., Cavalli, V. & DiAntonio, A., Jun 21 2012, In: Neuron. 74, 6, p. 1015-1022 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    208 Scopus citations
  • Dynamics of anterior-posterior axis formation in the developing mouse embryo

    Morris, S. A., Grewal, S., Barrios, F., Patankar, S. N., Strauss, B., Buttery, L., Alexander, M., Shakesheff, K. M. & Zernicka-Goetz, M., 2012, In: Nature communications. 3, 673.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    61 Scopus citations
  • Exploring the DNA-recognition potential of homeodomains

    Chu, S. W., Noyes, M. B., Christensen, R. G., Pierce, B. G., Zhu, L. J., Weng, Z., Stormo, G. D. & Wolfe, S. A., Oct 2012, In: Genome research. 22, 10, p. 1889-1898 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • Fast, sensitive discovery of conserved genome-wide motifs

    Ihuegbu, N. E., Stormo, G. D. & Buhler, J., Feb 1 2012, In: Journal of Computational Biology. 19, 2, p. 139-147 9 p.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • FTO genotype is associated with phenotypic variability of body mass index

    Yang, J., Loos, R. J. F., Powell, J. E., Medland, S. E., Speliotes, E. K., Chasman, D. I., Rose, L. M., Thorleifsson, G., Steinthorsdottir, V., Mägi, R., Waite, L., Vernon Smith, A., Yerges-Armstrong, L. M., Monda, K. L., Hadley, D., Mahajan, A., Li, G., Kapur, K., Vitart, V., Huffman, J. E., & 152 othersWang, S. R., Palmer, C., Esko, T., Fischer, K., Hua Zhao, J., Demirkan, A., Isaacs, A., Feitosa, M. F., Luan, JA., Heard-Costa, N. L., White, C., Jackson, A. U., Preuss, M., Ziegler, A., Eriksson, J., Kutalik, Z., Frau, F., Nolte, I. M., Van Vliet-Ostaptchouk, J. V., Hottenga, J. J., Jacobs, K. B., Verweij, N., Goel, A., Medina-Gomez, C., Estrada, K., Bragg-Gresham, J. L., Sanna, S., Sidore, C., Tyrer, J., Teumer, A., Prokopenko, I., Mangino, M., Lindgren, C. M., Assimes, T. L., Shuldiner, A. R., Hui, J., Beilby, J. P., McArdle, W. L., Hall, P., Haritunians, T., Zgaga, L., Kolcic, I., Polasek, O., Zemunik, T., Oostra, B. A., Juhani Junttila, M., Grönberg, H., Schreiber, S., Peters, A., Hicks, A. A., Stephens, J., Foad, N. S., Laitinen, J., Pouta, A., Kaakinen, M., Willemsen, G., Vink, J. M., Wild, S. H., Navis, G., Asselbergs, F. W., Homuth, G., John, U., Iribarren, C., Harris, T., Launer, L., Gudnason, V., O'Connell, J. R., Boerwinkle, E., Cadby, G., Palmer, L. J., James, A. L., Musk, A. W., Ingelsson, E., Psaty, B. M., Beckmann, J. S., Waeber, G., Vollenweider, P., Hayward, C., Wright, A. F., Rudan, I., Groop, L. C., Metspalu, A., Tee Khaw, K., Van Duijn, C. M., Borecki, I. B., Province, M. A., Wareham, N. J., Tardif, J. C., Huikuri, H. V., Adrienne Cupples, L., Atwood, L. D., Fox, C. S., Boehnke, M., Collins, F. S., Mohlke, K. L., Erdmann, J., Schunkert, H., Hengstenberg, C., Stark, K., Lorentzon, M., Ohlsson, C., Cusi, D., Staessen, J. A., Van Der Klauw, M. M., Pramstaller, P. P., Kathiresan, S., Jolley, J. D., Ripatti, S., Jarvelin, M. R., De Geus, E. J. C., Boomsma, D. I., Penninx, B., Wilson, J. F., Campbell, H., Chanock, S. J., Van Der Harst, P., Hamsten, A., Watkins, H., Hofman, A., Witteman, J. C., Carola Zillikens, M., Uitterlinden, A. G., Rivadeneira, F., Carola Zillikens, M., Kiemeney, L. A., Vermeulen, S. H., Abecasis, G. R., Schlessinger, D., Schipf, S., Stumvoll, M., Tönjes, A., Spector, T. D., North, K. E., Lettre, G., McCarthy, M. I., Berndt, S. I., Heath, A. C., Madden, P. A. F., Nyholt, D. R., Montgomery, G. W., Martin, N. G., McKnight, B., Strachan, D. P., Hill, W. G., Snieder, H., Ridker, P. M., Thorsteinsdottir, U., Stefansson, K., Frayling, T. M., Hirschhorn, J. N., Goddard, M. E. & Visscher, P. M., Oct 11 2012, In: Nature. 490, 7419, p. 267-273 7 p.

    Research output: Contribution to journalArticlepeer-review

    288 Scopus citations
  • Gene-Centric Meta-Analysis of Lipid Traits in African, East Asian and Hispanic Populations

    Elbers, C. C., Guo, Y., Tragante, V., van Iperen, E. P. A., Lanktree, M. B., Castillo, B. A., Chen, F., Yanek, L. R., Wojczynski, M. K., Li, Y. R., Ferwerda, B., Ballantyne, C. M., Buxbaum, S. G., Chen, Y. D. I., Chen, W. M., Cupples, L. A., Cushman, M., Duan, Y., Duggan, D., Evans, M. K., & 50 othersFernandes, J. K., Fornage, M., Garcia, M., Garvey, W. T., Glazer, N., Gomez, F., Harris, T. B., Halder, I., Howard, V. J., Keller, M. F., Kamboh, M. I., Kooperberg, C., Kritchevsky, S. B., LaCroix, A., Liu, K., Liu, Y., Musunuru, K., Newman, A. B., Onland-Moret, N. C., Ordovas, J., Peter, I., Post, W., Redline, S., Reis, S. E., Saxena, R., Schreiner, P. J., Volcik, K. A., Wang, X., Yusuf, S., Zonderland, A. B., Anand, S. S., Becker, D. M., Psaty, B., Rader, D. J., Reiner, A. P., Rich, S. S., Rotter, J. I., Sale, M. M., Tsai, M. Y., Borecki, I. B., Hegele, R. A., Kathiresan, S., Nalls, M. A., Taylor, H. A., Hakonarson, H., Sivapalaratnam, S., Asselbergs, F. W., Drenos, F., Wilson, J. G. & Keating, B. J., Dec 7 2012, In: PloS one. 7, 12, e50198.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    34 Scopus citations
  • Genome-wide association and functional follow-up reveals new loci for kidney function

    Pattaro, C., Köttgen, A., Teumer, A., Garnaas, M., Böger, C. A., Fuchsberger, C., Olden, M., Chen, M. H., Tin, A., Taliun, D., Li, M., Gao, X., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C., O'Seaghdha, C. M., Glazer, N., Isaacs, A., Liu, C. T., & 146 othersSmith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Johnson, A. D., Gierman, H. J., Feitosa, M., Hwang, S. J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, Å., Tönjes, A., Dehghan, A., Chouraki, V., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimäki, T., Esko, T., Deshmukh, H., Ulivi, S., Chu, A. Y., Murgia, F., Trompet, S., Imboden, M., Kollerits, B., Pistis, G., Harris, T. B., Launer, L. J., Aspelund, T., Eiriksdottir, G., Mitchell, B. D., Boerwinkle, E., Schmidt, H., Cavalieri, M., Rao, M., Hu, F. B., Demirkan, A., Oostra, B. A., de Andrade, M., Turner, S. T., Ding, J., Andrews, J. S., Freedman, B. I., Koenig, W., Illig, T., Döring, A., Wichmann, H. E., Kolcic, I., Zemunik, T., Boban, M., Minelli, C., Wheeler, H. E., Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Nöthlings, U., Jacobs, G., Biffar, R., Endlich, K., Ernst, F., Homuth, G., Kroemer, H. K., Nauck, M., Stracke, S., Völker, U., Völzke, H., Kovacs, P., Stumvoll, M., Mägi, R., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Aulchenko, Y. S., Polasek, O., Hastie, N., Vitart, V., Helmer, C., Wang, J. J., Ruggiero, D., Bergmann, S., Kähönen, M., Viikari, J., Nikopensius, T., Province, M., Ketkar, S., Colhoun, H., Doney, A., Robino, A., Giulianini, F., Krämer, B. K., Portas, L., Ford, I., Buckley, B. M., Adam, M., Thun, G. A., Paulweber, B., Haun, M., Sala, C., Metzger, M., Mitchell, P., Ciullo, M., Kim, S. K., Vollenweider, P., Raitakari, O., Metspalu, A., Palmer, C., Gasparini, P., Pirastu, M., Jukema, J. W., Probst-Hensch, N. M., Kronenberg, F., Toniolo, D., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Ferrucci, L., Siscovick, D. S., van Duijn, C. M., Borecki, I., Kardia, S. L. R., Liu, Y., Curhan, G. C., Rudan, I., Gyllensten, U., Wilson, J. F., Franke, A., Pramstaller, P. P., Rettig, R., Prokopenko, I., Witteman, J. C. M., Hayward, C., Ridker, P., Parsa, A., Bochud, M., Heid, I. M., Goessling, W., Chasman, D. I., Kao, W. H. L. & Fox, C. S., Mar 2012, In: PLoS genetics. 8, 3, e1002584.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    142 Scopus citations
  • Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

    Wilk, J. B., Shrine, N. R. G., Loehr, L. R., Zhao, J. H., Manichaikul, A., Lopez, L. M., Smith, A. V., Heckbert, S. R., Smolonska, J., Tang, W., Loth, D. W., Curjuric, I., Hui, J., Cho, M. H., Latourelle, J. C., Henry, A. P., Aldrich, M., Bakke, P., Beaty, T. H., Bentley, A. R., & 59 othersBorecki, I. B., Brusselle, G. G., Burkart, K. M., Chen, T. H., Couper, D., Crapo, J. D., Davies, G., Dupuis, J., Franceschini, N., Gulsvik, A., Hancock, D. B., Harris, T. B., Hofman, A., Imboden, M., James, A. L., Khaw, K. T., Lahousse, L., Launer, L. J., Litonjua, A., Liu, Y., Lohman, K. K., Lomas, D. A., Lumley, T., Marciante, K. D., McArdle, W. L., Meibohm, B., Morrison, A. C., Musk, A. W., Myers, R. H., North, K. E., Postma, D. S., Psaty, B. M., Rich, S. S., Rivadeneira, F., Rochat, T., Rotter, J. I., Soler Artigas, M., Starr, J. M., Uitterlinden, A. G., Wareham, N. J., Wijmenga, C., Zanen, P., Province, M. A., Silverman, E. K., Deary, I. J., Palmer, L. J., Cassano, P. A., Gudnason, V., Barr, R. G., Loos, R. J. F., Strachan, D. P., London, S. J., Boezen, H. M., Probst-Hensch, N., Gharib, S. A., Hall, I. P., O'Connor, G. T., Tobin, M. D. & Stricker, B. H., Oct 1 2012, In: American journal of respiratory and critical care medicine. 186, 7, p. 622-632 11 p.

    Research output: Contribution to journalArticlepeer-review

    143 Scopus citations
  • Genome-wide association study to identify common variants associated with brachial circumference: A meta-analysis of 14 cohorts

    Boraska, V., Day-Williams, A., Franklin, C. S., Elliott, K. S., Panoutsopoulou, K., Tachmazidou, I., Albrecht, E., Bandinelli, S., Beilin, L. J., Bochud, M., Cadby, G., Ernst, F., Evans, D. M., Hayward, C., Hicks, A. A., Huffman, J., Huth, C., James, A. L., Klopp, N., Kolcic, I., & 46 othersKutalik, Z., Lawlor, D. A., Musk, A. W., Pehlic, M., Pennell, C. E., Perry, J. R. B., Peters, A., Polasek, O., Pourcain, B. S., Ring, S. M., Salvi, E., Schipf, S., Staessen, J. A., Teumer, A., Timpson, N., Vitart, V., Warrington, N. M., Yaghootkar, H., Zemunik, T., Zgaga, L., An, P., Anttila, V., Borecki, I. B., Holmen, J., Ntalla, I., Palotie, A., Pietiläinen, K. H., Wedenoja, J., Winsvold, B. S., Dedoussis, G. V., Kaprio, J., Province, M. A., Zwart, J. A., Burnier, M., Campbell, H., Cusi, D., Davey Smith, G., Frayling, T. M., Gieger, C., Palmer, L. J., Pramstaller, P. P., Rudan, I., Völzke, H., Wichmann, H. E., Wright, A. F. & Zeggini, E., Mar 29 2012, In: PloS one. 7, 3, e31369.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Genome-wide meta-analysis points to CTC1 and ZNf676 as genes regulating telomere homeostasis in humans

    Mangino, M., Hwang, S. J., Spector, T. D., Hunt, S. C., Kimura, M., Fitzpatrick, A. L., Christiansen, L., Petersen, I., Elbers, C. C., Harris, T., Chen, W., Srinivasan, S. R., Kark, J. D., Benetos, A., El shamieh, S., Visvikis-Siest, S., Christensen, K., Berenson, G. S., Valdes, A. M., Vinuela, A., & 19 othersGarcia, M., Arnett, D. K., Broeckel, U., Province, M. A., Pankow, J. S., Kammerer, C., Liu, Y., Nalls, M., Tishkoff, S., Thomas, F., Ziv, E., Psaty, B. M., Bis, J. C., Rotter, J. I., Taylor, K. D., Smith, E., Schork, N. J., Levy, D. & Aviv, A., Dec 2012, In: Human molecular genetics. 21, 24, p. 5385-5394 10 p., dds382.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    158 Scopus citations
  • Global gene deletion analysis exploring yeast filamentous growth

    Ryan, O., Shapiro, R. S., Kurat, C. F., Mayhew, D., Baryshnikova, A., Chin, B., Lin, Z. Y., Cox, M. J., Vizeacoumar, F., Cheung, D., Bahr, S., Tsui, K., Tebbji, F., Sellam, A., Istel, F., Schwarzmüller, T., Reynolds, T. B., Kuchler, K., Gifford, D. K., Whiteway, M., & 9 othersGiaever, G., Nislow, C., Costanzo, M., Gingras, A. C., Mitra, R. D., Andrews, B., Fink, G. R., Cowen, L. E. & Boone, C., Sep 14 2012, In: Science. 337, 6100, p. 1352-1356 5 p.

    Research output: Contribution to journalArticlepeer-review

    142 Scopus citations
  • Healing quantitative trait loci in a combined cross analysis using related mouse strain crosses

    Cheverud, J. M., Lawson, H. A., Funk, R., Zhou, J., Blankenhorn, E. P. & Heber-Katz, E., Apr 2012, In: Heredity. 108, 4, p. 441-446 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    15 Scopus citations
  • High Fat Diet Induced Developmental Defects in the Mouse: Oocyte Meiotic Aneuploidy and Fetal Growth Retardation/Brain Defects

    Luzzo, K. M., Wang, Q., Purcell, S. H., Chi, M., Jimenez, P. T., Grindler, N., Schedl, T. & Moley, K. H., Nov 12 2012, In: PloS one. 7, 11, e49217.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    226 Scopus citations
  • Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature

    Rinkevich, Y., Mori, T., Sahoo, D., Xu, P. X., Bermingham, J. R. & Weissman, I. L., Dec 2012, In: Nature Cell Biology. 14, 12, p. 1251-1260 10 p.

    Research output: Contribution to journalArticlepeer-review

    120 Scopus citations
  • Impact of common variation in bone-related genes on type 2 diabetes and related traits

    Billings, L. K., Hsu, Y. H., Ackerman, R. J., Dupuis, J., Voight, B. F., Rasmussen-Torvik, L. J., Hercberg, S., Lathrop, M., Barnes, D., Langenberg, C., Hui, J., Fu, M., Bouatia-Naji, N., Lecoeur, C., An, P., Magnusson, P. K., Surakka, I., Ripatti, S., Christiansen, L., Dalgård, C., & 20 othersFolkersen, L., Grundberg, E., Eriksson, P., Kaprio, J., Kyvik, K. O., Pedersen, N. L., Borecki, I. B., Province, M. A., Balkau, B., Froguel, P., Shuldiner, A. R., Palmer, L. J., Wareham, N., Meneton, P., Johnson, T., Pankow, J. S., Karasik, D., Meigs, J. B., Kiel, D. P. & Florez, J. C., Aug 2012, In: Diabetes. 61, 8, p. 2176-2186 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • Improved models for transcription factor binding site identification using nonindependent interactions

    Zhao, Y., Ruan, S., Pandey, M. & Stormo, G. D., Jul 1 2012, In: Genetics. 191, 3, p. 781-790 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    90 Scopus citations
  • Imputation of single-nucleotide polymorphisms in inbred mice using local phylogeny

    Wang, J. R., de Villena, F. P. M., Lawson, H. A., Cheverud, J. M., Churchill, G. A. & McMillan, L., Feb 2012, In: Genetics. 190, 2, p. 449-458 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    36 Scopus citations
  • Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

    Hartz, S. M., Short, S. E., Saccone, N. L., Culverhouse, R., Chen, L. S., Schwantes-An, T. H., Coon, H., Han, Y., Stephens, S. H., Sun, J., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Geller, F., Guobjartsson, D., Hansel, N. N., Jiang, C., Keskitalo-Vuokko, K., & 132 othersLiu, Z., Lyytikäinen, L. P., Michel, M., Rawal, R., Rosenberger, A., Scheet, P., Shaffer, J. R., Teumer, A., Thompson, J. R., Vink, J. M., Vogelzangs, N., Wenzlaff, A. S., Wheeler, W., Xiao, X., Yang, B. Z., Aggen, S. H., Balmforth, A. J., Baumeister, S. E., Beaty, T., Bennett, S., Bergen, A. W., Boyd, H. A., Broms, U., Campbell, H., Chatterjee, N., Chen, J., Cheng, Y. C., Cichon, S., Couper, D., Cucca, F., Dick, D. M., Foroud, T., Furberg, H., Giegling, I., Gu, F., Hall, A. S., Hällfors, J., Han, S., Hartmann, A. M., Hayward, C., Heikkilä, K., Hewitt, J. K., Hottenga, J. J., Jensen, M. K., Jousilahti, P., Kaakinen, M., Kittner, S. J., Konte, B., Korhonen, T., Landi, M. T., Laatikainen, T., Leppert, M., Levy, S. M., Mathias, R. A., McNeil, D. W., Medland, S. E., Montgomery, G. W., Muley, T., Murray, T., Nauck, M., North, K., Pergadia, M., Polasek, O., Ramos, E. M., Ripatti, S., Risch, A., Ruczinski, I., Rudan, I., Salomaa, V., Schlessinger, D., Styrkársdóttir, U., Terracciano, A., Uda, M., Willemsen, G., Wu, X., Abecasis, G., Barnes, K., Bickeböller, H., Boerwinkle, E., Boomsma, D. I., Caporaso, N., Duan, J., Edenberg, H. J., Francks, C., Gejman, P. V., Gelernter, J., Grabe, H. J., Hops, H., Jarvelin, M. R., Viikari, J., Kähönen, M., Kendler, K. S., Lehtimäki, T., Levinson, D. F., Marazita, M. L., Marchini, J., Melbye, M., Mitchell, B. D., Murray, J. C., Nöthen, M. M., Penninx, B. W., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N. J., Sanders, A. R., Schwartz, A. G., Shete, S., Shi, J., Spitz, M., Stefansson, K., Swan, G. E., Thorgeirsson, T., Völzke, H., Wei, Q., Wichmann, H. E., Amos, C. I., Breslau, N., Cannon, D. S., Ehringer, M., Grucza, R., Hatsukami, D., Heath, A., Johnson, E. O., Kaprio, J., Madden, P., Martin, N. G., Stevens, V. L., Stitzel, J. A., Weiss, R. B., Kraft, P. & Bierut, L. J., Aug 2012, In: Archives of General Psychiatry. 69, 8, p. 854-861 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    59 Scopus citations
  • Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

    Chasman, D. I., Fuchsberger, C., Pattaro, C., Teumer, A., Böger, C. A., Endlich, K., Olden, M., Chen, M. H., Tin, A., Taliun, D., Li, M., Gao, X., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C., O'Seaghdha, C. M., Glazer, N., Isaacs, A., Liu, C. T., & 144 othersSmith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Johnson, A. D., Gierman, H. J., Feitosa, M. F., Hwang, S. J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, Å., Tönjes, A., Dehghan, A., Lambert, J. C., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimäki, T., Esko, T., Deshmukh, H., Ulivi, S., Chu, A. Y., Murgia, F., Trompet, S., Imboden, M., Coassin, S., Pistis, G., Harris, T. B., Launer, L. J., Aspelund, T., Eiriksdottir, G., Mitchell, B. D., Boerwinkle, E., Schmidt, H., Cavalieri, M., Rao, M., Hu, F., Demirkan, A., Oostra, B. A., de Andrade, M., Turner, S. T., Ding, J., Andrews, J. S., Freedman, B. I., Giulianini, F., Koenig, W., Illig, T., Meisinger, C., Gieger, C., Zgaga, L., Zemunik, T., Boban, M., Minelli, C., Wheeler, H. E., Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Nöthlings, U., Jacobs, G., Biffar, R., Ernst, F., Homuth, G., Kroemer, H. K., Nauck, M., Stracke, S., Völker, U., Völzke, H., Kovacs, P., Stumvoll, M., Mägi, R., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Aulchenko, Y. S., Polasek, O., Hastie, N., Vitart, V., Helmer, C., Wang, J. J., Stengel, B., Ruggiero, D., Bergmann, S., Kähönen, M., Viikari, J., Nikopensius, T., Province, M., Ketkar, S., Colhoun, H., Doney, A., Robino, A., Krämer, B. K., Portas, L., Ford, I., Buckley, B. M., Adam, M., Thun, G. A., Paulweber, B., Haun, M., Sala, C., Mitchell, P., Ciullo, M., Kim, S. K., Vollenweider, P., Raitakari, O., Metspalu, A., Palmer, C., Gasparini, P., Pirastu, M., Jukema, J. W., Probst-Hensch, N. M., Kronenberg, F., Toniolo, D., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Ferrucci, L., Siscovick, D. S., van Duijn, C. M., Borecki, I. B., Kardia, S. L. R., Liu, Y., Curhan, G. C., Rudan, I., Gyllensten, U., Wilson, J. F., Franke, A., Pramstaller, P. P., Rettig, R., Prokopenko, I., Witteman, J., Hayward, C., Ridker, P. M., Parsa, A., Bochud, M., Heid, I. M., Kao, W. H. L., Fox, C. S. & Köttgen, A., Dec 2012, In: Human molecular genetics. 21, 24, p. 5329-5343 15 p.

    Research output: Contribution to journalArticlepeer-review

    53 Scopus citations
  • Interplay of genetic risk factors (CHRNA 5-CHRNA 3-CHRNB4) and cessation treatments in smoking cessation success

    Chen, L. S., Baker, T. B., Piper, M. E., Breslau, N., Cannon, D. S., Doheny, K. F., Gogarten, S. M., Johnson, E. O., Saccone, N. L., Wang, J. C., Weiss, R. B., Goate, A. M. & Bierut, L. J., Jul 1 2012, In: American Journal of Psychiatry. 169, 7, p. 735-742 8 p.

    Research output: Contribution to journalArticlepeer-review

    106 Scopus citations
  • IS-seq: a novel high throughput survey of in vivo IS6110 transposition in multiple Mycobacterium tuberculosis genomes

    Reyes, A., Sandoval, A., Cubillos-Ruiz, A., Varley, K. E., Hernández-Neuta, I., Samper, S., Martín, C., García, M. J., Ritacco, V., López, L., Robledo, J., Zambrano, M. M., Mitra, R. D. & Del Portillo, P., Jun 15 2012, In: BMC genomics. 13, 1, 249.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    22 Scopus citations
  • JAK inhibition with tofacitinib suppresses arthritic joint structural damage through decreased RANKL production

    Labranche, T. P., Jesson, M. I., Radi, Z. A., Storer, C. E., Guzova, J. A., Bonar, S. L., Thompson, J. M., Happa, F. A., Stewart, Z. S., Zhan, Y., Bollinger, C. S., Bansal, P. N., Wellen, J. W., Wilkie, D. P., Bailey, S. A., Symanowicz, P. T., Hegen, M., Head, R. D., Kishore, N., Mbalaviele, G., & 1 othersMeyer, D. M., Nov 2012, In: Arthritis and rheumatism. 64, 11, p. 3531-3542 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    99 Scopus citations
  • Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

    Scott, R. A., Lagou, V., Welch, R. P., Wheeler, E., Montasser, M. E., Luan, JA., MäGi, R., Strawbridge, R. J., Rehnberg, E., Gustafsson, S., Kanoni, S., Rasmussen-Torvik, L. J., Yengo, L., Lecoeur, C., Shungin, D., Sanna, S., Sidore, C., Johnson, P. C. D., Jukema, J. W., Johnson, T., & 194 othersMahajan, A., Verweij, N., Thorleifsson, G., Hottenga, J. J., Shah, S., Smith, A. V., Sennblad, B., Gieger, C., Salo, P., Perola, M., Timpson, N. J., Evans, D. M., Pourcain, B. S., Wu, Y., Andrews, J. S., Hui, J., Bielak, L. F., Zhao, W., Horikoshi, M., Navarro, P., Isaacs, A., O'Connell, J. R., Stirrups, K., Vitart, V., Hayward, C., Esko, T., Mihailov, E., Fraser, R. M., Fall, T., Voight, B. F., Raychaudhuri, S., Chen, H., Lindgren, C. M., Morris, A. P., Rayner, N. W., Robertson, N., Rybin, D., Liu, C. T., Beckmann, J. S., Willems, S. M., Chines, P. S., Jackson, A. U., Kang, H. M., Stringham, H. M., Song, K., Tanaka, T., Peden, J. F., Goel, A., Hicks, A. A., An, P., MüLler-Nurasyid, M., Franco-Cereceda, A., Folkersen, L., Marullo, L., Jansen, H., Oldehinkel, A. J., Bruinenberg, M., Pankow, J. S., North, K. E., Forouhi, N. G., Loos, R. J. F., Edkins, S., Varga, T. V., Hallmans, G., Oksa, H., Antonella, M., Nagaraja, R., Trompet, S., Ford, I., Bakker, S. J. L., Kong, A., Kumari, M., Gigante, B., Herder, C., Munroe, P. B., Caulfield, M., Antti, J., Mangino, M., Small, K., Miljkovic, I., Liu, Y., Atalay, M., Kiess, W., James, A. L., Rivadeneira, F., Uitterlinden, A. G., Palmer, C. N. A., Doney, A. S. F., Willemsen, G., Smit, J. H., Campbell, S., Polasek, O., Bonnycastle, L. L., Hercberg, S., Dimitriou, M., Bolton, J. L., Fowkes, G. R., Kovacs, P., LindströM, J., Zemunik, T., Bandinelli, S., Wild, S. H., Basart, H. V., Rathmann, W., Grallert, H., Maerz, W., Kleber, M. E., Boehm, B. O., Peters, A., Pramstaller, P. P., Province, M. A., Borecki, I. B., Hastie, N. D., Rudan, I., Campbell, H., Watkins, H., Farrall, M., Stumvoll, M., Ferrucci, L., Waterworth, D. M., Bergman, R. N., Collins, F. S., Tuomilehto, J., Watanabe, R. M., De Geus, E. J. C., Penninx, B. W., Hofman, A., Oostra, B. A., Psaty, B. M., Vollenweider, P., Wilson, J. F., Wright, A. F., Hovingh, G. K., Metspalu, A., Uusitupa, M., Magnusson, P. K. E., Kyvik, K. O., Kaprio, J., Price, J. F., Dedoussis, G. V., Deloukas, P., Meneton, P., Lind, L., Boehnke, M., Shuldiner, A. R., Van Duijn, C. M., Morris, A. D., Toenjes, A., Peyser, P. A., Beilby, J. P., KöRner, A., Kuusisto, J., Laakso, M., Bornstein, S. R., Schwarz, P. E. H., Lakka, T. A., Rauramaa, R., Adair, L. S., Smith, G. D., Spector, T. D., Illig, T., Faire, U. D., Hamsten, A., Gudnason, V., Kivimaki, M., Hingorani, A., Keinanen-Kiukaanniemi, S. M., Saaristo, T. E., Boomsma, D. I., Stefansson, K., Van Der Harst, P., Dupuis, J., Pedersen, N. L., Sattar, N., Harris, T. B., Cucca, F., Ripatti, S., Salomaa, V., Mohlke, K. L., Balkau, B., Froguel, P., Pouta, A., Jarvelin, M. R., Wareham, N. J., Bouatia-Naji, N., McCarthy, M. I., Franks, P. W., Meigs, J. B., Teslovich, T. M., Florez, J. C., Langenberg, C., Ingelsson, E., Prokopenko, I. & Barroso, I., Sep 2012, In: Nature Genetics. 44, 9, p. 991-1005 15 p.

    Research output: Contribution to journalArticlepeer-review

    587 Scopus citations
  • Medicago truncatula transporter database: A comprehensive database resource for M. truncatula transporters

    Miao, Z., Li, D., Zhang, Z., Dong, J., Su, Z. & Wang, T., Feb 6 2012, In: BMC genomics. 13, 1, 60.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

    Okada, Y., Sim, X., Go, M. J., Wu, J. Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S. C., Wong, T. Y., Liu, J., Young, T. L., Aung, T., Seielstad, M., Teo, Y. Y., Kim, Y. J., Lee, J. Y., Han, B. G., & 469 othersKang, D., Chen, C. H., Tsai, F. J., Chang, L. C., Fann, S. J., Mei, H., Rao, D. C., Hixson, J. E., Chen, S., Katsuya, T., Isono, M., Ogihara, T., Chambers, J. C., Zhang, W., Kooner, J. S., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y. T., Cho, Y. S., Tai, E. S., Tanaka, T., Chambers, J. C., Zhang, W., Lord, G. M., van der Harst, P., Lawlor, D. A., Sehmi, J. S., Gale, D. P., Wass, M. N., Ahmadi, K. R., Bakker, S. J., Beckmann, J., Bilo, H. J., Bochud, M., Brown, M. J., Caulfield, M. J., Connell, J. M., Cook, H. T., Cotlarciuc, I., Smith, G. D., de Silva, R., Deng, G., Devuyst, O., Dikkeschei, L. 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