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  • 2013

    Common variants in mendelian kidney disease genes and their association with renal function

    Parsa, A., Fuchsberger, C., Köttgen, A., O'Seaghdha, C. M., Pattaro, C., De Andrade, M., Chasman, D. I., Teumer, A., Endlich, K., Olden, M., Chen, M. H., Tin, A., Kim, Y. J., Taliun, D., Li, M., Feitosa, M., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C. & 139 others, Glazer, N., Isaacs, A., Rao, M., Smith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Hwang, S. J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, A., Tönjes, A., Dehghan, A., Couraki, V., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimäki, T., Esko, T., Deshmukh, H., Ulivi, S., Chu, A. Y., Murgia, F., Trompet, S., Imboden, M., Kollerits, B., Pistis, G., Harris, T. B., Launer, L. J., Aspelund, T., Eiriksdottir, G., Mitchell, B. D., Boerwinkle, E., Schmidt, H., Hofer, E., Hu, F., Demirkan, A., Oostra, B. A., Turner, S. T., Ding, J., Andrews, J. S., Freedman, B. I., Giulianini, F., Koenig, W., Illig, T., Döring, A., Wichmann, H. E., Zgaga, L., Zemunik, T., Boban, M., Minelli, C., Wheeler, H. E., Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Nöthlings, U., Jacobs, G., Biffar, R., Ernst, F., Homuth, G., Kroemer, H. K., Nauck, M., Stracke, S., Völker, U., Völzke, H., Kovacs, P., Stumvoll, M., Mägi, R., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Aulchenko, Y. S., Polasek, O., Hastie, N., Vitart, V., Helmer, C., Wang, J. J., Stengel, B., Ruggiero, D., Bergmann, S., Kähönen, M., Viikari, J., Nikopensius, T., Province, M., Colhoun, H., Doney, A., Robino, A., Krämer, B. K., Portas, L., Ford, I., Buckley, B. M., Adam, M., Thun, G. A., Paulweber, B., Haun, M., Sala, C., Mitchell, P., Ciullo, M., Vollenweider, P., Raitakari, O., Metspalu, A., Palmer, C., Gasparini, P., Pirastu, M., Jukema, J. W., Probst-Hensch, N. M., Kronenberg, F., Toniolo, D., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Ferrucci, L., Van Duijn, C. M., Borecki, I., Kardia, S. L. R., Liu, Y., Curhan, G. C., Rudan, I., Gyllensten, U., Wilson, J. F., Franke, A., Pramstaller, P. P., Rettig, R., Prokopenko, I., Witteman, J., Hayward, C., Ridker, P. M., Bochud, M., Heid, I. M., Siscovick, D. S., Fox, C. S., Kao, W. L. & Böger, C. A., 2013, In: Journal of the American Society of Nephrology. 24, 12, p. 2105-2117 13 p.

    Research output: Contribution to journalArticlepeer-review

    26 Scopus citations
  • Creation and preliminary characterization of a Tp53 knockout rat

    McCoy, A., Besch-Williford, C. L., Franklin, C. L., Weinstein, E. J. & Cui, X., Jan 2013, In: DMM Disease Models and Mechanisms. 6, 1, p. 269-278 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • Open Access
    14 Scopus citations
  • Depleting gene activities in early drosophila embryos with the "maternal-Gal4-shRNA" system

    Staller, M. V., Yan, D., Randklev, S., Bragdon, M. D., Wunderlich, Z. B., Tao, R., Perkins, L. A., De Pace, A. H. & Perrimon, N., Jan 2013, In: Genetics. 193, 1, p. 51-61 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    58 Scopus citations
  • Development of translating ribosome affinity purification for zebrafish

    Tryon, R. C., Pisat, N., Johnson, S. L. & Dougherty, J. D., Mar 2013, In: Genesis. 51, 3, p. 187-192 6 p.

    Research output: Contribution to journalArticlepeer-review

    30 Scopus citations
  • Discovery of Anthelmintic Drug Targets and Drugs Using Chokepoints in Nematode Metabolic Pathways

    Taylor, C. M., Wang, Q., Rosa, B. A., Huang, S. C. C., Powell, K., Schedl, T., Pearce, E. J., Abubucker, S. & Mitreva, M., Aug 2013, In: PLoS pathogens. 9, 8, e1003505.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    60 Scopus citations
  • Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

    Stephens, S. H., Hartz, S. M., Hoft, N. R., Saccone, N. L., Corley, R. C., Hewitt, J. K., Hopfer, C. J., Breslau, N., Coon, H., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Han, Y., Hansel, N. N., Jiang, C., Korhonen, T., Lind, P. A., Liu, J. & 106 others, Lyytikäinen, L. P., Michel, M., Shaffer, J. R., Short, S. E., Sun, J., Teumer, A., Thompson, J. R., Vogelzangs, N., Vink, J. M., Wenzlaff, A., Wheeler, W., Yang, B. Z., Aggen, S. H., Balmforth, A. J., Baumeister, S. E., Beaty, T. H., Benjamin, D. J., Bergen, A. W., Broms, U., Cesarini, D., Chatterjee, N., Chen, J., Cheng, Y. C., Cichon, S., Couper, D., Cucca, F., Dick, D., Foroud, T., Furberg, H., Giegling, I., Gillespie, N. A., Gu, F., Hall, A. S., Hällfors, J., Han, S., Hartmann, A. M., Heikkilä, K., Hickie, I. B., Hottenga, J. J., Jousilahti, P., Kaakinen, M., Kähönen, M., Koellinger, P. D., Kittner, S., Konte, B., Landi, M. T., Laatikainen, T., Leppert, M., Levy, S. M., Mathias, R. A., Mcneil, D. W., Medland, S. E., Montgomery, G. W., Murray, T., Nauck, M., North, K. E., Paré, P. D., Pergadia, M., Ruczinski, I., Salomaa, V., Viikari, J., Willemsen, G., Barnes, K. C., Boerwinkle, E., Boomsma, D. I., Caporaso, N., Edenberg, H. J., Francks, C., Gelernter, J., Grabe, H. J., Hops, H., Jarvelin, M. R., Johannesson, M., Kendler, K. S., Lehtimäki, T., Magnusson, P. K. E., Marazita, M. L., Marchini, J., Mitchell, B. D., Nöthen, M. M., Penninx, B. W., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N. J., Schwartz, A. G., Shete, S., Spitz, M., Swan, G. E., Völzke, H., Veijola, J., Wei, Q., Amos, C., Cannon, D. S., Grucza, R., Hatsukami, D., Heath, A., Johnson, E. O., Kaprio, J., Madden, P., Martin, N. G., Stevens, V. L., Weiss, R. B., Kraft, P., Bierut, L. J. & Ehringer, M. A., Dec 2013, In: Genetic Epidemiology. 37, 8, p. 846-859 14 p.

    Research output: Contribution to journalArticlepeer-review

    29 Scopus citations
  • DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape

    Xie, M., Hong, C., Zhang, B., Lowdon, R. F., Xing, X., Li, D., Zhou, X., Lee, H. J., Maire, C. L., Ligon, K. L., Gascard, P., Sigaroudinia, M., Tlsty, T. D., Kadlecek, T., Weiss, A., O'Geen, H., Farnham, P. J., Madden, P. A. F., Mungall, A. J., Tam, A. & 7 others, Kamoh, B., Cho, S., Moore, R., Hirst, M., Marra, M. A., Costello, J. F. & Wang, T., Jul 2013, In: Nature Genetics. 45, 7, p. 836-841 6 p.

    Research output: Contribution to journalArticlepeer-review

    140 Scopus citations
  • DNA unmethylome profiling by covalent capture of CpG sites

    Kriukiene, E., Labrie, V., Khare, T., Urbanavičiute, G., Lapinaite, A., Koncevičius, K., Li, D., Wang, T., Pai, S., Ptak, C., Gordevičius, J., Wang, S. C., Petronis, A. & Klimašauskas, S., 2013, In: Nature communications. 4, 2190.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    38 Scopus citations
  • Effects upon in-vivo nicotine metabolism reveal functional variation in FMO3 associated with cigarette consumption

    Bloom, A. J., Murphy, S. E., Martinez, M., Von Weymarn, L. B., Bierut, L. J. & Goate, A., Feb 2013, In: Pharmacogenetics and Genomics. 23, 2, p. 62-68 7 p.

    Research output: Contribution to journalArticlepeer-review

    23 Scopus citations
  • Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods

    Stevens, M., Cheng, J. B., Li, D., Xie, M., Hong, C., Maire, C. L., Ligon, K. L., Hirst, M., Marra, M. A., Costello, J. F. & Wang, T., Sep 2013, In: Genome research. 23, 9, p. 1541-1553 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    111 Scopus citations
  • Exceptional memory performance in the Long Life Family Study

    Barral, S., Cosentino, S., Costa, R., Andersen, S. L., Christensen, K., Eckfeldt, J. H., Newman, A. B., Perls, T. T., Province, M. A., Hadley, E. C., Rossi, W. K. & Mayeux, R., Nov 2013, In: Neurobiology of Aging. 34, 11, p. 2445-2448 4 p.

    Research output: Contribution to journalArticlepeer-review

    17 Scopus citations
  • Expression and function of scalloped during Drosophila development

    Guss, K. A., Benson, M., Gubitosi, N., Brondell, K., Broadie, K. & Skeath, J. B., Jul 2013, In: Developmental Dynamics. 242, 7, p. 874-885 12 p.

    Research output: Contribution to journalArticlepeer-review

    13 Scopus citations
  • Families enriched for exceptional longevity also have increased health-span: Findings from the long life family study

    Sebastiani, P., Sun, F. X., Andersen, S. L., Lee, J. H., Wojczynski, M. K., Sanders, J. L., Yashin, A., Newman, A. B. & Perls, T. T., Sep 30 2013, In: Frontiers in Public Health. 1, SEP, p. 38 1 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    49 Scopus citations
  • Flow cytometry-based enrichment for cell shape mutants identifies multiple genes that influence Helicobacter pylori morphology

    Sycuro, L. K., Rule, C. S., Petersen, T. W., Wyckoff, T. J., Sessler, T., Nagarkar, D. B., Khalid, F., Pincus, Z., Biboy, J., Vollmer, W. & Salama, N. R., Nov 2013, In: Molecular Microbiology. 90, 4, p. 869-883 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    59 Scopus citations
  • Functional characterization of piggyBat from the bat Myotis lucifugus unveils an active mammalian DNA transposon

    Mitra, R., Li, X., Kapusta, A., Mayhew, D., Mitra, R. D., Feschotte, C. & Craig, N. L., Jan 2 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 1, p. 234-239 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    49 Scopus citations
  • Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm

    Zhang, B., Zhou, Y., Lin, N., Lowdon, R. F., Hong, C., Nagarajan, R. P., Cheng, J. B., Li, D., Stevens, M., Lee, H. J., Xing, X., Zhou, J., Sundaram, V., Elliott, G., Gu, J., Shi, T., Gascard, P., Sigaroudinia, M., Tlsty, T. D., Kadlecek, T. & 13 others, Weiss, A., O'Geen, H., Farnham, P. J., Maire, C. L., Ligon, K. L., Madden, P. A. F., Tam, A., Moore, R., Hirst, M., Marra, M. A., Zhang, B., Costello, J. F. & Wang, T., Sep 2013, In: Genome research. 23, 9, p. 1522-1540 19 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    116 Scopus citations
  • Gene Expression Analysis of Zebrafish Melanocytes, Iridophores, and Retinal Pigmented Epithelium Reveals Indicators of Biological Function and Developmental Origin

    Higdon, C. W., Mitra, R. D. & Johnson, S. L., Jul 9 2013, In: PloS one. 8, 7, e67801.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    62 Scopus citations
  • Genetic analysis of 16 NMR-lipoprotein fractions in humans, the GOLDN study

    Kraja, A. T., Borecki, I. B., Tsai, M. Y., Ordovas, J. M., Hopkins, P. N., Lai, C. Q., Frazier-Wood, A. C., Straka, R. J., Hixson, J. E., Province, M. A. & Arnett, D. K., Feb 2013, In: Lipids. 48, 2, p. 155-165 11 p.

    Research output: Contribution to journalArticlepeer-review

    28 Scopus citations
  • Genetics of coronary artery calcification among African Americans, a meta-analysis

    Wojczynski, M. K., Li, M., Bielak, L. F., Kerr, K. F., Reiner, A. P., Wong, N. D., Yanek, L. R., Qu, L., White, C. C., Lange, L. A., Ferguson, J. F., He, J., Young, T., Mosley, T. H., Smith, J. A., Kral, B. G., Guo, X., Wong, Q., Ganesh, S. K., Heckbert, S. R. & 25 others, Griswold, M. E., O'Leary, D. H., Budoff, M., Carr, J. J., Taylor, H. A., Bluemke, D. A., Demissie, S., Hwang, S. J., Paltoo, D. N., Polak, J. F., Psaty, B. M., Becker, D. M., Province, M. A., Post, W. S., O'Donnell, C. J., Wilson, J. G., Harris, T. B., Kavousi, M., Cupples, L. A., Rotter, J. I., Fornage, M., Becker, L. C., Peyser, P. A., Borecki, I. B. & Reilly, M. P., Jul 19 2013, In: BMC Medical Genetics. 14, 1, 75.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    54 Scopus citations
  • Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: The long life family study

    Lee, J. H., Cheng, R., Honig, L. S., Feitosa, M., Kammerer, C. M., Kang, M. S., Schupf, N., Lin, S. J., Sanders, J. L., Bae, H., Druley, T., Perls, T., Christensen, K., Province, M. & Mayeux, R., 2013, In: Frontiers in Genetics. 4, JAN, Article 310.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    45 Scopus citations
  • Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci

    Liu, C. T., Monda, K. L., Taylor, K. C., Lange, L., Demerath, E. W., Palmas, W., Wojczynski, M. K., Ellis, J. C., Vitolins, M. Z., Liu, S., Papanicolaou, G. J., Irvin, M. R., Xue, L., Griffin, P. J., Nalls, M. A., Adeyemo, A., Liu, J., Li, G., Ruiz-Narvaez, E. A., Chen, W. M. & 73 others, Chen, F., Henderson, B. E., Millikan, R. C., Ambrosone, C. B., Strom, S. S., Guo, X., Andrews, J. S., Sun, Y. V., Mosley, T. H., Yanek, L. R., Shriner, D., Haritunians, T., Rotter, J. I., Speliotes, E. K., Smith, M., Rosenberg, L., Mychaleckyj, J., Nayak, U., Spruill, I., Garvey, W. T., Pettaway, C., Nyante, S., Bandera, E. V., Britton, A. F., Zonderman, A. B., Rasmussen-Torvik, L. J., Chen, Y. D. I., Ding, J., Lohman, K., Kritchevsky, S. B., Zhao, W., Peyser, P. A., Kardia, S. L. R., Kabagambe, E., Broeckel, U., Chen, G., Zhou, J., Wassertheil-Smoller, S., Neuhouser, M. L., Rampersaud, E., Psaty, B., Kooperberg, C., Manson, J. A. E., Kuller, L. H., Ochs-Balcom, H. M., Johnson, K. C., Sucheston, L., Ordovas, J. M., Palmer, J. R., Haiman, C. A., McKnight, B., Howard, B. V., Becker, D. M., Bielak, L. F., Liu, Y., Allison, M. A., Grant, S. F. A., Burke, G. L., Patel, S. R., Schreiner, P. J., Borecki, I. B., Evans, M. K., Taylor, H., Sale, M. M., Howard, V., Carlson, C. S., Rotimi, C. N., Cushman, M., Harris, T. B., Reiner, A. P., Cupples, L. A., North, K. E. & Fox, C. S., Aug 2013, In: PLoS genetics. 9, 8, e1003681.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    93 Scopus citations
  • Genome-wide characterization of endogenous retroviruses in the bat Myotis lucifugus reveals recent and diverse infections

    Zhuo, X., Rho, M. & Feschotte, C., 2013, In: Journal of virology. 87, 15, p. 8493-8501 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    29 Scopus citations
  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Berndt, S. I., Gustafsson, S., Mägi, R., Ganna, A., Wheeler, E., Feitosa, M. F., Justice, A. E., Monda, K. L., Croteau-Chonka, D. C., Day, F. R., Esko, T., Fall, T., Ferreira, T., Gentilini, D., Jackson, A. U., Luan, J., Randall, J. C., Vedantam, S., Willer, C. J., Winkler, T. W. & 302 others, Wood, A. R., Workalemahu, T., Hu, Y. J., Lee, S. H., Liang, L., Lin, D. Y., Min, J. L., Neale, B. M., Thorleifsson, G., Yang, J., Albrecht, E., Amin, N., Bragg-Gresham, J. L., Cadby, G., Heijer, M. D., Eklund, N., Fischer, K., Goel, A., Hottenga, J. J., Huffman, J. E., Jarick, I., Johansson, Å., Johnson, T., Kanoni, S., Kleber, M. E., König, I. R., Kristiansson, K., Kutalik, Z., Lamina, C., Lecoeur, C., Li, G., Mangino, M., McArdle, W. L., Medina-Gomez, C., Müller-Nurasyid, M., Ngwa, J. S., Nolte, I. M., Paternoster, L., Pechlivanis, S., Perola, M., Peters, M. J., Preuss, M., Rose, L. M., Shi, J., Shungin, D., Smith, A. V., Strawbridge, R. J., Surakka, I., Teumer, A., Trip, M. D., Tyrer, J., Van Vliet-Ostaptchouk, J. V., Vandenput, L., Waite, L. L., Zhao, J. H., Absher, D., Asselbergs, F. W., Atalay, M., Attwood, A. P., Balmforth, A. J., Basart, H., Beilby, J., Bonnycastle, L. L., Brambilla, P., Bruinenberg, M., Campbell, H., Chasman, D. I., Chines, P. S., Collins, F. S., Connell, J. M., O Cookson, W., De Faire, U., De Vegt, F., Dei, M., Dimitriou, M., Edkins, S., Estrada, K., Evans, D. M., Farrall, M., Ferrario, M. M., Ferrières, J., Franke, L., Frau, F., Gejman, P. V., Grallert, H., Grönberg, H., Gudnason, V., Hall, A. S., Hall, P., Hartikainen, A. L., Hayward, C., Heard-Costa, N. L., Heath, A. C., Hebebrand, J., Homuth, G., Hu, F. B., Hunt, S. E., Hyppönen, E., Iribarren, C., Jacobs, K. B., Jansson, J. O., Jula, A., Kähönen, M., Kathiresan, S., Kee, F., Khaw, K. T., Kivimäki, M., Koenig, W., Kraja, A. T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Laitinen, J. H., Lakka, T. A., Langenberg, C., Launer, L. J., Lind, L., Lindström, J., Liu, J., Liuzzi, A., Lokki, M. L., Lorentzon, M., Madden, P. A., Magnusson, P. K., Manunta, P., Marek, D., März, W., Leach, I. M., McKnight, B., Medland, S. E., Mihailov, E., Milani, L., Montgomery, G. W., Mooser, V., Mühleisen, T. W., Munroe, P. B., Musk, A. W., Narisu, N., Navis, G., Nicholson, G., Nohr, E. A., Ong, K. K., Oostra, B. A., Palmer, C. N., Palotie, A., Peden, J. F., Pedersen, N., Peters, A., Polasek, O., Pouta, A., Pramstaller, P. P., Prokopenko, I., Pütter, C., Radhakrishnan, A., Raitakari, O., Rendon, A., Rivadeneira, F., Rudan, I., Saaristo, T. E., Sambrook, J. G., Sanders, A. R., Sanna, S., Saramies, J., Schipf, S., Schreiber, S., Schunkert, H., Shin, S. Y., Signorini, S., Sinisalo, J., Skrobek, B., Soranzo, N., Stancáková, A., Stark, K., Stephens, J. C., Stirrups, K., Stolk, R. P., Stumvoll, M., Swift, A. J., Theodoraki, E. V., Thorand, B., Tregouet, D. A., Tremoli, E., Van Der Klauw, M. M., Van Meurs, J. B., Vermeulen, S. H., Viikari, J., Virtamo, J., Vitart, V., Waeber, G., Wang, Z., Widén, E., Wild, S. H., Willemsen, G., Winkelmann, B. R., Witteman, J. C., Wolffenbuttel, B. H., Wong, A., Wright, A. F., Zillikens, M. C., Amouyel, P., Boehm, B. O., Boerwinkle, E., Boomsma, D. I., Caulfield, M. J., Chanock, S. J., Cupples, L. A., Cusi, D., Dedoussis, G. V., Erdmann, J., Eriksson, J. G., Franks, P. W., Froguel, P., Gieger, C., Gyllensten, U., Hamsten, A., Harris, T. B., Hengstenberg, C., Hicks, A. A., Hingorani, A., Hinney, A., Hofman, A., Hovingh, K. G., Hveem, K., Illig, T., Jarvelin, M. R., Jöckel, K. H., Keinanen-Kiukaanniemi, S. M., Kiemeney, L. A., Kuh, D., Laakso, M., Lehtimäki, T., Levinson, D. F., Martin, N. G., Metspalu, A., Morris, A. D., Nieminen, M. S., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Ouwehand, W. H., Palmer, L. J., Penninx, B., Power, C., Province, M. A., Psaty, B. M., Qi, L., Rauramaa, R., Ridker, P. M., Ripatti, S., Salomaa, V., Samani, N. J., Snieder, H., Sørensen, T. I., Spector, T. D., Stefansson, K., Tönjes, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Van Der Harst, P., Vollenweider, P., Wallaschofski, H., Wareham, N. J., Watkins, H., Wichmann, H. E., Wilson, J. F., Abecasis, G. R., Assimes, T. L., Barroso, I., Boehnke, M., Borecki, I. B., Deloukas, P., Fox, C. S., Frayling, T., Groop, L. C., Haritunian, T., Heid, I. M., Hunter, D., Kaplan, R. C., Karpe, F., Moffatt, M. F., Mohlke, K. L., O'Connell, J. R., Pawitan, Y., Schadt, E. E., Schlessinger, D., Steinthorsdottir, V., Strachan, D. P., Thorsteinsdottir, U., Van Duijn, C. M., Visscher, P. M., Di Blasio, A. M., Hirschhorn, J. N., Lindgren, C. M., Morris, A. P., Meyre, D., Scherag, A., McCarthy, M. I., Speliotes, E. K., North, K. E., Loos, R. J. & Ingelsson, E., May 2013, In: Nature Genetics. 45, 5, p. 501-512 12 p.

    Research output: Contribution to journalArticlepeer-review

    399 Scopus citations
  • Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake

    Tanaka, T., Ngwa, J. S., Van Rooij, F. J. A., Zillikens, M. C., Wojczynski, M. K., Frazier-Wood, A. C., Houston, D. K., Kanoni, S., Lemaitre, R. N., Luan, J. N. A., Mikkilä, V., Renstrom, F., Sonestedt, E., Zhao, J. H., Chu, A. Y., Qi, L., Chasman, D. I., De Oliveira Otto, M. C., Dhurandhar, E. J., Feitosa, M. F. & 46 others, Johansson, I., Khaw, K. T., Lohman, K. K., Manichaikul, A., McKeown, N. M., Mozaffarian, D., Singleton, A., Stirrups, K., Viikari, J., Ye, Z., Bandinelli, S., Barroso, I., Deloukas, P., Forouhi, N. G., Hofman, A., Liu, Y., Lyytikäinen, L. P., North, K. E., Dimitriou, M., Hallmans, G., Kähönen, M., Langenberg, C., Ordovas, J. M., Uitterlinden, A. G., Hu, F. B., Kalafati, I. P., Raitakari, O., Franco, O. H., Johnson, A., Emilsson, V., Schrack, J. A., Semba, R. D., Siscovick, D. S., Arnett, D. K., Borecki, I. B., Franks, P. W., Kritchevsky, S. B., Loos, T. L. R. J. F., Orho-Melander, M., Rotter, J. I., Wareham, N. J., Witteman, J. C. M., Ferrucci, L., Dedoussis, G., Cupples, L. A. & Nettleton, J. A., Jun 1 2013, In: American Journal of Clinical Nutrition. 97, 6, p. 1395-1402 8 p.

    Research output: Contribution to journalArticlepeer-review

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    156 Scopus citations
  • Global analysis of Drosophila Cys2-His2 zinc finger proteins reveals a multitude of novel recognition motifs and binding determinants

    Enuameh, M. S., Asriyan, Y., Richards, A., Christensen, R. G., Hall, V. L., Kazemian, M., Zhu, C., Pham, H., Cheng, Q., Blatti, C., Brasefield, J. A., Basciotta, M. D., Ou, J., McNulty, J. C., Zhu, L. J., Celniker, S. E., Sinha, S., Stormo, G. D., Brodsky, M. H. & Wolfe, S. A., Jun 2013, In: Genome research. 23, 6, p. 928-940 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    53 Scopus citations
  • GWAS of cerebrospinal fluid tau levels identifies risk variants for alzheimer's disease

    Cruchaga, C., Kauwe, J. S. K., Harari, O., Jin, S. C., Cai, Y., Karch, C. M., Benitez, B. A., Jeng, A. T., Skorupa, T., Carrell, D., Bertelsen, S., Bailey, M., McKean, D., Shulman, J. M., De Jager, P. L., Chibnik, L., Bennett, D. A., Arnold, S. E., Harold, D., Sims, R. & 17 others, Gerrish, A., Williams, J., Van Deerlin, V. M., Lee, V. M. Y., Shaw, L. M., Trojanowski, J. Q., Haines, J. L., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A., Schellenberg, G. D., Peskind, E. R., Galasko, D., Fagan, A. M., Holtzman, D. M., Morris, J. C. & Goate, A. M., Apr 24 2013, In: Neuron. 78, 2, p. 256-268 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    234 Scopus citations
  • Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE consortium studies1-4

    Hruby, A., Ngwa, J. S., Renström, F., Mary, M. K., Ganna, A., Hallmans, G., Houston, D. K., Jacques, P. F., Kanoni, S., Lehtimäki, T., Lemaitre, R. N., Manichaikul, A., North, K. E., Ntalla, I., Sonestedt, E., Tanaka, T., van Rooij, F. J. A., Bandinelli, S., Djoussé, L., Grigoriou, E. & 39 others, Johansson, I., Lohman, K. K., Pankow, J. S., Raitakari, O. T., Riserus, U., Yannakoulia, M., Zillikens, M. C., Hassanali, N., Liu, Y., Mozaffarian, D., Papoutsakis, C., Syvänen, A. C., Uitterlinden, A. G., Viikari, J., Groves, C. J., Lind, A. H., Lind, L., McCarthy, M. I., Mikkilä̈, V., Mukamal, K., Franco, O. H., Borecki, I. B., Cupples, L. A., Dedoussis, G. V., Ferrucci, L., Hu, F. B., Ingelsson, E., Kähönen, M., Kao, W. H. L., Kritchevsky, S. B., Orho-Melander, M., Prokopenko, I., Rotter, J. I., Siscovick, D. S., Witteman, J. C. M., Franks, P. W., Meigs, J. B., McKeown, N. M. & Nettleton, J. A., Mar 2013, In: Journal of Nutrition. 143, 3, p. 345-353 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    45 Scopus citations
  • Identification of cilia genes that affect cell-cycle progression using whole-genome transcriptome analysis in chlamydomonas reinhardtti

    Albee, A. J., Kwan, A. L., Lin, H., Granas, D., Stormo, G. D. & Dutcher, S. K., Jun 2013, In: G3: Genes, Genomes, Genetics. 3, 6, p. 979-991 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    31 Scopus citations
  • Imputation across genotyping arrays for genome-wide association studies: Assessment of bias and a correction strategy

    Johnson, E. O., Hancock, D. B., Levy, J. L., Gaddis, N. C., Saccone, N. L., Bierut, L. J. & Page, G. P., May 2013, In: Human genetics. 132, 5, p. 509-522 14 p.

    Research output: Contribution to journalArticlepeer-review

    28 Scopus citations
  • Interpreting joint SNP analysis results: When are two distinct signals really two distinct signals?

    Schwantes-An, T. H., Culverhouse, R., Duan, W., Ramnarine, S., Rice, J. P. & Saccone, N. L., Apr 2013, In: Genetic Epidemiology. 37, 3, p. 301-309 9 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • Katanin Localization Requires Triplet Microtubules in Chlamydomonas reinhardtii

    Esparza, J. M., O'Toole, E., Li, L., Giddings, T. H., Kozak, B., Albee, A. J. & Dutcher, S. K., Jan 8 2013, In: PloS one. 8, 1, e53940.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • Laser capture microdissection-reduced representation bisulfite sequencing (LCM-RRBS) maps changes in DNA methylation associated with gonadectomy-induced adrenocortical neoplasia in the mouse

    Schillebeeckx, M., Schrade, A., Löbs, A. K., Pihlajoki, M., Wilson, D. B. & Mitra, R. D., Jun 2013, In: Nucleic acids research. 41, 11, p. e116

    Research output: Contribution to journalArticlepeer-review

    Open Access
    32 Scopus citations
  • Lipoprotein receptor-related protein 1 variants and dietary fatty acids: Meta-analysis of European origin and African American studies

    Smith, C. E., Ngwa, J., Tanaka, T., Qi, Q., Wojczynski, M. K., Lemaitre, R. N., Anderson, J. S., Manichaikul, A., Mikkilä, V., Van Rooij, F. J. A., Ye, Z., Bandinelli, S., Frazier-Wood, A. C., Houston, D. K., Hu, F., Langenberg, C., McKeown, N. M., Mozaffarian, D., North, K. E., Viikari, J. & 28 others, Zillikens, M. C., Djoussé, L., Hofman, A., Kähönen, M., Kabagambe, E. K., Loos, R. J. F., Saylor, G. B., Forouhi, N. G., Liu, Y., Mukamal, K. J., Chen, Y. D., Tsai, M. Y., Uitterlinden, A. G., Raitakari, O., Van Duijn, C. M., Arnett, D. K., Borecki, I. B., Cupples, L. A., Ferrucci, L., Kritchevsky, S. B., Lehtimäki, T., Qi, L., Rotter, J. I., Siscovick, D. S., Wareham, N. J., Witteman, J. C. M., Ordovás, J. M. & Nettleton, J. A., Sep 2013, In: International Journal of Obesity. 37, 9, p. 1211-1220 10 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Loss of the spectraplakin short stop activates the DLK injury response pathway in drosophila

    Valakh, V., Walker, L. J., Skeath, J. B. & DiAntonio, A., 2013, In: Journal of Neuroscience. 33, 45, p. 17863-17873 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    43 Scopus citations
  • LRRC6 Mutation Causes Primary Ciliary Dyskinesia with Dynein Arm Defects

    Horani, A., Ferkol, T. W., Shoseyov, D., Wasserman, M. G., Oren, Y. S., Kerem, B., Amirav, I., Cohen-Cymberknoh, M., Dutcher, S. K., Brody, S. L., Elpeleg, O. & Kerem, E., Mar 19 2013, In: PloS one. 8, 3, e59436.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    59 Scopus citations
  • 126 Scopus citations
  • Massively parallel synthetic promoter assays reveal the in vivo effects of binding site variants

    Mogno, I., Kwasnieski, J. C. & Cohen, B. A., Nov 2013, In: Genome research. 23, 11, p. 1908-1915 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    62 Scopus citations
  • Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts

    Nettleton, J. A., Hivert, M. F., Lemaitre, R. N., McKeown, N. M., Mozaffarian, D., Tanaka, T., Wojczynski, M. K., Hruby, A., Djoussé, L., Ngwa, J. S., Follis, J. L., Dimitriou, M., Ganna, A., Houston, D. K., Kanoni, S., Mikkilä, V., Manichaikul, A., Ntalla, I., Renström, F., Sonestedt, E. & 45 others, Van Rooij, F. J. A., Bandinelli, S., De Koning, L., Ericson, U., Hassanali, N., Kiefte-De Jong, J. C., Lohman, K. K., Raitakari, O., Papoutsakis, C., Sjogren, P., Stirrups, K., Ax, E., Deloukas, P., Groves, C. J., Jacques, P. F., Johansson, I., Liu, Y., McCarthy, M. I., North, K., Viikari, J., Zillikens, M. C., Dupuis, J., Hofman, A., Kolovou, G., Mukamal, K., Prokopenko, I., Rolandsson, O., Seppälä, I., Cupples, L. A., Hu, F. B., Kähönen, M., Uitterlinden, A. G., Borecki, I. B., Ferrucci, L., Jacobs, D. R., Kritchevsky, S. B., Orho-Melander, M., Pankow, J. S., Lehtimäki, T., Witteman, J. C. M., Ingelsson, E., Siscovick, D. S., Dedoussis, G., Meigs, J. B. & Franks, P. W., Jan 2013, In: American journal of epidemiology. 177, 2, p. 103-115 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    63 Scopus citations
  • Meta-analysis of gene-level associations for rare variants based on single-variant statistics

    Hu, Y. J., Berndt, S. I., Gustafsson, S., Ganna, A., Ingelsson, E., Hirschhorn, J., North, K. E., Lin, D. Y., Berndt, S. I., Gustafsson, S., Mägi, R., Ganna, A., Wheeler, E., Feitosa, M. F., Justice, A. E., Monda, K. L., Croteau-Chonka, D. C., Day, F. R., Esko, T., Fall, T. & 307 others, Ferreira, T., Gentilini, D., Jackson, A. U., Luan, J., Randall, J. C., Vedantam, S., Willer, C. J., Winkler, T. W., Wood, A. R., Workalemahu, T., Hu, Y. J., Lee, S. H., Liang, L., Lin, D. Y., Min, J. L., Neale, B. M., Thorleifsson, G., Yang, J., Albrecht, E., Amin, N., Bragg-Gresham, J. L., Cadby, G., Heijer, M. D., Eklund, N., Fischer, K., Goel, A., Hottenga, J. J., Huffman, J. E., Jarick, I., Johansson, A., Johnson, T., Kanoni, S., Kleber, M. E., König, I. R., Kristiansson, K., Kutalik, Z., Lamina, C., Lecoeur, C., Li, G., Mangino, M., McArdle, W. L., Medina-Gomez, C., Müller-Nurasyid, M., Ngwa, J. S., Nolte, I. M., Paternoster, L., Pechlivanis, S., Perola, M., Peters, M. J., Preuss, M., Rose, L. M., Shi, J., Shungin, D., Smith, A. V., Strawbridge, R. J., Surakka, I., Teumer, A., Trip, M. D., Tyrer, J., Vliet-Ostaptchouk, J. V. V., Vandenput, L., Waite, L. L., Zhao, J. H., Absher, D., Asselbergs, F. W., Atalay, M., Attwood, A. P., Balmforth, A. J., Basart, H., Beilby, J., Bonnycastle, L. L., Brambilla, P., Bruinenberg, M., Campbell, H., Chasman, D. I., Chines, P. S., Connell, J. M., Cookson, W., Faire, U. D., Vegt, F. D., Dei, M., Dimitriou, M., Edkins, S., Estrada, K., Evans, D. M., Farrall, M., Ferrario, M. M., Ferrières, J., Franke, L., Frau, F., Gejman, P. V., Grallert, H., Grönberg, H., Gudnason, V., Hall, A. S., Hall, P., Hartikainen, A. L., Hayward, C., Heard-Costa, N. L., Heath, A. C., Hebebrand, J., Homuth, G., Hu, F. B., Hunt, S. E., Hyppönen, E., Iribarren, C., Jacobs, K. B., Jansson, J. O., Jula, A., Kähönen, M., Kathiresan, S., Kee, F., Khaw, K. T., Kivimaki, M., Koenig, W., Kraja, A. T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Laitinen, J. H., Lakka, T. A., Langenberg, C., Launer, L. J., Lind, L., Lindström, J., Liu, J., Liuzzi, A., Lokki, M. L., Lorentzon, M., Magnusson, P. A. M., Magnusson, P. A. M., Manunta, P., Marek, D., März, W., Leach, I. M., McKnight, B., Medland, S. E., Mihailov, E., Milani, L., Montgomery, G. W., Mooser, V., Mühleisen, T. W., Munroe, P. B., Musk, A. W., Narisu, N., Navis, G., Nicholson, G., Nohr, E. A., Ong, K. K., Oostra, B. A., Palmer, C. N. A., Palotie, A., Peden, J. F., Pedersen, N., Peters, A., Polasek, O., Pouta, A., Pramstaller, P. P., Prokopenko, I., Pütter, C., Radhakrishnan, A., Raitakari, O., Rendon, A., Rivadeneira, F., Rudan, I., Saaristo, T. E., Sambrook, J. G., Sanders, A. R., Sanna, S., Saramies, J., Schipf, S., Schreiber, S., Schunkert, H., Shin, S. Y., Signorini, S., Sinisalo, J., Skrobek, B., Soranzo, N., Stancáková, A., Stark, K., Stephens, J. C., Stirrups, K., Stolk, R. P., Stumvoll, M., Swift, A. J., Theodoraki, E. V., Thorand, B., Tregouet, D. A., Tremoli, E., Klauw, M. M. V. D., Meurs, J. B. J. V., Vermeulen, S. H., Viikari, J., Virtamo, J., Vitart, V., Waeber, G., Wang, Z., Widén, E., Wild, S. H., Willemsen, G., Winkelmann, B. R., Witteman, J. C. M., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zillikens, M. C., Amouyel, P., Boehm, B. O., Boerwinkle, E., Boomsma, D. I., Caulfield, M. J., Chanock, S. J., Cupples, L. A., Cusi, D., Dedoussis, G. V., Erdmann, J., Eriksson, J. G., Franks, P. W., Froguel, P., Gieger, C., Gyllensten, U., Hamsten, A., Harris, T. B., Hengstenberg, C., Hicks, A. A., Hingorani, A., Hinney, A., Hofman, A., Hovingh, K. G., Hveem, K., Illig, T., Jarvelin, M. R., Jöckel, K. H., Keinanen-Kiukaanniemi, S. M., Kiemeney, L. A., Kuh, D., Laakso, M., Lehtimäki, T., Levinson, D. F., Martin, N. G., Metspalu, A., Morris, A. D., Nieminen, M. S., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Ouwehand, W. H., Palmer, L. J., Penninx, B., Power, C., Province, M. A., Psaty, B. M., Qi, L., Rauramaa, R., Ridker, P. M., Ripatti, S., Salomaa, V., Samani, N. J., Snieder, H., Sørensen, T. I. A., Spector, T. D., Stefansson, K., Tönjes, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Harst, P. V. D., Vollenweider, P., Wallaschofski, H., Wareham, N. J., Watkins, H., Wichmann, H. E., Wilson, J. F., Abecasis, G. R., Assimes, T. L., Barroso, I., Boehnke, M., Borecki, I. B., Deloukas, P., Fox, C. S., Frayling, T., Groop, L. C., Haritunian, T., Heid, I. M., Hunter, D., Kaplan, R. C., Karpe,MiriamMoffatt, F., Mohlke, K. L., O’Connell, J. R., Pawitan, Y., Schadt, E. E., Schlessinger, D., Steinthorsdottir, V., Strachan, D. P., Thorsteinsdottir, U., Duijn, C. M. V., Visscher, P. M., Blasio, A. M. D., Hirschhorn, J. N., Lindgren, C. M., Morris, A. P., Meyre, D., Scherag, A., McCarthy, M. I., Speliotes, E. K., North, K. E. & Loos, R. J. F., Aug 8 2013, In: American journal of human genetics. 93, 2, p. 236-248 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    44 Scopus citations
  • N-cadherin relocalizes from the periphery to the center of the synapse after transient synaptic stimulation in hippocampal neurons

    Yam, P. T., Pincus, Z., Gupta, G. D., Bashkurov, M., Charron, F., Pelletier, L. & Colman, D. R., Nov 2013, In: PloS one. 8, 11, e79679.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • New mutations in flagellar motors identified by whole genome sequencing in Chlamydomonas

    Lin, H., Nauman, N. P., Albee, A. J., Hsu, S. & Dutcher, S. K., Oct 30 2013, In: Cilia. 2, 1, 14.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    20 Scopus citations
  • Plot protein: Visualization of mutations

    Turner, T., Jul 22 2013, In: Journal of Clinical Bioinformatics. 3, 1, 14.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • PNPLA3 gene-by-visceral adipose tissue volume interaction and the pathogenesis of fatty liver disease: The NHLBI Family Heart Study

    Graff, M., North, K. E., Franceschini, N., Reiner, A. P., Feitosa, M., Carr, J. J., Gordon-Larsen, P., Wojczynski, M. K. & Borecki, I. B., Mar 2013, In: International Journal of Obesity. 37, 3, p. 432-438 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    38 Scopus citations
  • Protection of mouse retinal ganglion cell axons and soma from glaucomatous and ischemic injury by cytoplasmic overexpression of Nmnat1

    Zhu, Y., Zhang, L., Sasaki, Y., Milbrandt, J. & Gidday, J. M., Jan 2013, In: Investigative Ophthalmology and Visual Science. 54, 1, p. 25-36 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    50 Scopus citations
  • Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression

    Culverhouse, R. C., Bowes, L., Breslau, N., Nurnberger, J. I., Burmeister, M., Fergusson, D. M., Munafò, M., Saccone, N. L. & Bierut, L. J., Nov 12 2013, In: BMC Psychiatry. 13, 304.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    32 Scopus citations
  • Radiosynthesis and biological evaluation of alpha-[F-18]fluoromethyl phenylalanine for brain tumor imaging

    Huang, C., Yuan, L., Rich, K. M. & McConathy, J., May 2013, In: Nuclear Medicine and Biology. 40, 4, p. 498-506 9 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Reexposure to nicotine during withdrawal increases the pacemaking activity of cholinergic habenular neurons

    Görlich, A., Antolin-Fontes, B., Ables, J. L., Frahm, S., Ślimak, M. A., Dougherty, J. D. & Ibañez-Tallon, I., Oct 15 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 42, p. 17077-17082 6 p.

    Research output: Contribution to journalArticlepeer-review

    73 Scopus citations
  • Regulation of dopamine presynaptic markers and receptors in the striatum of DJ-1 and pink1 knockout rats

    Sun, J., Kouranova, E., Cui, X., Mach, R. H. & Xu, J., Dec 17 2013, In: Neuroscience Letters. 557, PB, p. 123-128 6 p.

    Research output: Contribution to journalArticlepeer-review

    20 Scopus citations
  • Role of oxygen consumption in hypoxia protection by translation factor depletion

    Scott, B., Sun, C. L., Mao, X., Yu, C., Vohra, B. P. S., Milbrandt, J. & Crowder, C. M., Jun 2013, In: Journal of Experimental Biology. 216, 12, p. 2283-2292 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations