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  • 2014

    An improved predictive recognition model for Cys2-His 2 zinc finger proteins

    Gupta, A., Christensen, R. G., Bell, H. A., Goodwin, M., Patel, R. Y., Pandey, M., Enuameh, M. S., Rayla, A. L., Zhu, C., Thibodeau-Beganny, S., Brodsky, M. H., Joung, J. K., Wolfe, S. A. & Stormo, G. D., Apr 2014, In: Nucleic acids research. 42, 8, p. 4800-4812 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    51 Scopus citations
  • Antigen detection based on background fluorescence quenching immunochromatographic assay

    Chen, X., Xu, Y., Yu, J., Li, J., Zhou, X., Wu, C., Ji, Q., Ren, Y., Wang, L., Huang, Z., Zhuang, H., Piao, L., Head, R., Wang, Y. & Lou, J., Sep 2 2014, In: Analytica Chimica Acta. 841, p. 44-50 7 p.

    Research output: Contribution to journalArticlepeer-review

    24 Scopus citations
  • Anti-VEGF antibodies mitigate the development of radiation necrosis in mouse brain

    Jiang, X., Engelbach, J. A., Yuan, L., Cates, J., Gao, F., Drzymala, R. E., Hallahan, D. E., Rich, K., Schmidt, R. E., Ackerman, J. J. H. & Garbow, J. R., May 15 2014, In: Clinical Cancer Research. 20, 10, p. 2695-2702 8 p.

    Research output: Contribution to journalArticlepeer-review

    54 Scopus citations
  • A Requirement for ERK-Dependent Dicer Phosphorylation in Coordinating Oocyte-to-Embryo Transition in C.elegans

    Drake, M., Furuta, T., Suen, K. M., Gonzalez, G., Liu, B., Kalia, A., Ladbury, J. E., Fire, A. Z., Skeath, J. B. & Arur, S., Dec 8 2014, In: Developmental cell. 31, 5, p. 614-628 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    47 Scopus citations
  • Beyond cigarettes per day: A genome-wide association study of the biomarker carbon monoxide

    Bloom, A. J., Hartz, S. M., Baker, T. B., Chen, L. S., Piper, M. E., Fox, L., Martinez, M., Hatsukami, D., Johnson, E. O., Laurie, C. C., Saccone, N. L., Goate, A. & Bierut, L. J., Sep 1 2014, In: Annals of the American Thoracic Society. 11, 7, p. 1003-1010 8 p.

    Research output: Contribution to journalArticlepeer-review

    30 Scopus citations
  • Causal Variation in Yeast Sporulation Tends to Reside in a Pathway Bottleneck

    Lorenz, K. & Cohen, B. A., Sep 1 2014, In: PLoS genetics. 10, 9

    Research output: Contribution to journalArticlepeer-review

    Open Access
    11 Scopus citations
  • CellNet: Network biology applied to stem cell engineering

    Cahan, P., Li, H., Morris, S. A., Lummertz Da Rocha, E., Daley, G. Q. & Collins, J. J., Aug 14 2014, In: Cell. 158, 4, p. 903-915 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    340 Scopus citations
  • Cell type-specific expression analysis to identify putative cellular mechanisms for neurogenetic disorders

    Xu, X., Wells, A. B., O'Brien, D. R., Nehorai, A. & Dougherty, J. D., 2014, In: Journal of Neuroscience. 34, 4, p. 1420-1431 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    147 Scopus citations
  • Characterization of defects in ion transport and tissue development in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-knockout rats

    Tuggle, K. L., Birket, S. E., Cui, X., Hong, J., Warren, J., Reid, L., Chambers, A., Ji, D., Gamber, K., Chu, K. K., Tearney, G., Tang, L. P., Fortenberry, J. A., Du, M., Cadillac, J. M., Bedwell, D. M., Rowe, S. M., Sorscher, E. J. & Fanucchi, M. V., Mar 7 2014, In: PloS one. 9, 3, e91253.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    102 Scopus citations
  • Classical Flt3L-dependent dendritic cells control immunity to protein vaccine

    Anandasabapathy, N., Feder, R., Mollah, S., Tse, S. W., Longhi, M. P., Mehandru, S., Matos, I., Cheong, C., Ruane, D., Brane, L., Teixeira, A., Dobrin, J., Mizenina, O., Park, C. G., Meredith, M., Clausen, B. E., Nussenzweig, M. C. & Steinman, R. M., 2014, In: Journal of Experimental Medicine. 211, 9, p. 1875-1891 17 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    69 Scopus citations
  • Clinical and computed tomographic predictors of chronic bronchitis in COPD: A cross sectional analysis of the COPDGene study

    Kim, V., Davey, A., Comellas, A. P., Han, M. K., Washko, G., Martinez, C. H., Lynch, D., Lee, J. H., Silverman, E. K., Crapo, J. D., Make, B. J., Criner, G. J., Farzadegan, H., Bragan, S., Cayetano, S., Curtis, J., Kazerooni, E., Hanania, N., Alapat, P., Bandi, V. & 168 others, Guntupalli, K., Guy, E., Mallampalli, A., Trinh, C., Atik, M., Al-Azzawi, H., Willis, M., Pinero, S., Fahr, L., Nachiappan, A., Bray, C., Frigini, L. A., Farinas, C., Katz, D., Freytes, J., Marciel, A. M., DeMeo, D., Hersh, C., Jacobson, F., Hatabu, H., Clarke, P., Gill, R., Hunsaker, A., Trotman-Dickenson, B., Madan, R., Barr, R. G., Thomashow, B., Austin, J., D'Souza, B., MacIntyre, N., Washington, L., McAdams, H. P., Rosiello, R., Bresnahan, T., Bradley, J., Kuong, S., Meller, S., Roland, S., McEvoy, C., Tashjian, J., Wise, R., Hansel, N., Brown, R., Diette, G., Horton, K., Casaburi, R., Porszasz, J., Fischer, H., Budoff, M., Rambod, M., Sharafkhaneh, A., Kamal, H., Darvishi, R., Niewoehner, D., Anderson, Q., Rice, K., Caine, A., Foreman, M., Westney, G., Berkowitz, E., Bowler, R., Schroeder, J., Hale, V., Armstrong, J., Dyer, D., Chung, J., Cox, C., Marchetti, N., Satti, A., Mamary, A. J., Steiner, R., Dass, C., Cone, L., Bailey, W., Dransfield, M., Wells, M., Bhatt, S., Nath, H., Singh, S., Ramsdell, J., Friedman, P., Cornellas, A., Newell, J., van Beek, E. J. R., Martinez, F., Wendt, C., Allen, T., Sciurba, F., Weissfeld, J., Fuhrman, C., Bon, J., Hooper, D., Anzueto, A., Adams, S., Orozco, C., Ruiz, M., Mumbower, A., Kruger, A., Restrepo, C., Lane, M., Akhavan, J., Al Qaisi, M., Beaty, T., Black-Shinn, J., Bleecker, E. R., Bowler, R. P., Bratschie, S., Castaldic, P. J., Cho, M., Cox, C. W., Coxson, H. O., Croxton, T., Crystal, R. G., Curtis, J. L., Cusick, D., DeMeo, D. L., Dy, J. G., Everett, D., Foreman, M. G., Gan, W., Ginsburg, S., Hansel, N. N., Hardin, M. E., Hersh, C. P., Hetmanski, J., Hoffman, E. A., Hogg, J. C., Hokanson, J., Hokanson, J. E., Jensen, R., Jose Estepar, R. S., Judy, P. F., Kinney, G., Kluiber, A., Knowles, R., Laird, N., Lange, C., Lantz, R., Lutz, S. M., Mattheisen, M., McDonaldc, M. L., McKenzie, A., Melanson, S., Newell, J. D., Parker, M. M., Plant, R., Postow, L., Prieto, D., Province, M. A., Regan, E. A., Reilly, J. J., Rennard, S. I., Rossc, J., Santorico, S., Schroeder, J. D., Sieren, J., Sitek, A., Stepp, L., Stinson, D., Sutherland, E. R., Thomas, D. C., Walsh, J. W., Wan, E. S., Williams, A., Wilson, C., Zach, J., Zhou, J. & van Beek, E., Apr 27 2014, In: Respiratory Research. 15, 1, 52.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    67 Scopus citations
  • Coding variants in TREM2 increase risk for Alzheimer's disease

    Jin, S. C., Benitez, B. A., Karch, C. M., Cooper, B., Skorupa, T., Carrell, D., Norton, J. B., Hsu, S., Harari, O., Cai, Y., Bertelsen, S., Goate, A. M. & Cruchaga, C., Nov 1 2014, In: Human molecular genetics. 23, 21, p. 5838-5846 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    183 Scopus citations
  • Common genetic variants on 6q24 associated with exceptional episodic memory performance in the elderly

    Long Life Family Study, Dec 1 2014, In: JAMA Neurology. 71, 12, p. 1514-1519 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers

    Zhang, B., Xing, X. Y., Li, J., Lowdon, R. F., Zhou, Y., Lin, N., Zhang, B., Sundaram, V., Chiappinelli, K. B., Hagemann, I. S., Mutch, D. G., Goodfellow, P. J. & Wang, T., Oct 6 2014, In: BMC genomics. 15, 1, 868.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    47 Scopus citations
  • CYP2D6 Genotype and Adjuvant Tamoxifen: Meta-Analysis of Heterogeneous Study Populations

    Province, M. A., Goetz, M. P., Brauch, H., Flockhart, D. A., Hebert, J. M., Whaley, R., Suman, V. J., Schroth, W., Winter, S., Zembutsu, H., Mushiroda, T., Newman, W. G., Lee, M. T. M., Ambrosone, C. B., Beckmann, M. W., Choi, J. Y., Dieudonné, A. S., Fasching, P. A., Ferraldeschi, R., Gong, L. & 44 others, Haschke-Becher, E., Howell, A., Jordan, L. B., Hamann, U., Kiyotani, K., Krippl, P., Lambrechts, D., Latif, A., Langsenlehner, U., Lorizio, W., Neven, P., Nguyen, A. T., Park, B. W., Purdie, C. A., Quinlan, P., Renner, W., Schmidt, M., Schwab, M., Shin, J. G., Stingl, J. C., Wegman, P., Wingren, S., Wu, A. H. B., Ziv, E., Zirpoli, G., Thompson, A. M., Jordan, V. C., Nakamura, Y., Altman, R. B., Ames, M. M., Weinshilboum, R. M., Eichelbaum, M., Ingle, J. N., Klein, T. E., Boländer, J., Ulmer, H. U., Fischer-Bosch, M., Fritz, P., Simon, W., Bryan, Y., Strick, R., Koelbl, H., Ambrosone, C. A. & H, E. Z., Feb 1 2014, In: Clinical pharmacology and therapeutics. 95, 2, p. 216-227 12 p.

    Research output: Contribution to journalArticlepeer-review

    139 Scopus citations
  • Cytochrome p450 gene variants, race, and mortality among clopidogrel-treated patients after acute myocardial infarction

    Cresci, S., Depta, J. P., Lenzini, P. A., Li, A. Y., Lanfear, D. E., Province, M. A., Spertus, J. A. & Bach, R. G., Jun 2014, In: Circulation: Cardiovascular Genetics. 7, 3, p. 277-286 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    36 Scopus citations
  • Defining cellular identity through network biology

    Cahan, P., Morris, S. A., Collins, J. J. & Daley, G. Q., Nov 1 2014, In: Cell Cycle. 13, 21, p. 3313-3314 2 p., A1.

    Research output: Contribution to journalArticlepeer-review

    6 Scopus citations
  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Wood, A. R., Esko, T., Yang, J., Vedantam, S., Pers, T. H., Gustafsson, S., Chu, A. Y., Estrada, K., Luan, JA., Kutalik, Z., Amin, N., Buchkovich, M. L., Croteau-Chonka, D. C., Day, F. R., Duan, Y., Fall, T., Fehrmann, R., Ferreira, T., Jackson, A. U., Karjalainen, J. & 425 others, Lo, K. S., Locke, A., Mägi, R., Mihailov, E., Porcu, E., Randall, J. C., Scherag, A., Vinkhuyzen, A. A. E., Westra, H. J., Winkler, T. W., Workalemahu, T., Zhao, J. H., Absher, D., Albrecht, E., Anderson, D., Baron, J., Beekman, M., Demirkan, A., Ehret, G. B., Feenstra, B., Feitosa, M. F., Fischer, K., Fraser, R. M., Goel, A., Gong, J., Justice, A. E., Kanoni, S., Kleber, M. E., Kristiansson, K., Lim, U., Lotay, V., Lui, J. C., Mangino, M., Leach, I. M., Medina-Gomez, C., Nalls, M. A., Nyholt, D. R., Palmer, C. D., Pasko, D., Pechlivanis, S., Prokopenko, I., Ried, J. S., Ripke, S., Shungin, D., Stancáková, A., Strawbridge, R. J., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., Van Der Laan, S. W., Van Setten, J., Van Vliet-Ostaptchouk, J. V., Wang, Z., Yengo, L., Zhang, W., Afzal, U., Ärnlöv, J., Arscott, G. M., Bandinelli, S., Barrett, A., Bellis, C., Bennett, A. J., Berne, C., Blüher, M., Bolton, J. L., Böttcher, Y., Boyd, H. A., Bruinenberg, M., Buckley, B. M., Buyske, S., Caspersen, I. H., Chines, P. S., Clarke, R., Claudi-Boehm, S., Cooper, M., Daw, E. W., De Jong, P. A., Deelen, J., Delgado, G., Denny, J. C., Dhonukshe-Rutten, R., Dimitriou, M., Doney, A. S. F., Dörr, M., Eklund, N., Eury, E., Folkersen, L., Garcia, M. E., Geller, F., Giedraitis, V., Go, A. S., Grallert, H., Grammer, T. B., Gräßler, J., Grönberg, H., De Groot, L. C. P. G. M., Groves, C. J., Haessler, J., Hall, P., Haller, T., Hallmans, G., Hannemann, A., Hartman, C. A., Hassinen, M., Hayward, C., Heard-Costa, N. L., Helmer, Q., Hemani, G., Henders, A. K., Hillege, H. L., Hlatky, M. A., Hoffmann, W., Hoffmann, P., Holmen, O., Houwing-Duistermaat, J. J., Illig, T., Isaacs, A., James, A. L., Jeff, J., Johansen, B., Johansson, Å., Jolley, J., Juliusdottir, T., Junttila, J., Kho, A. N., Kinnunen, L., Klopp, N., Kocher, T., Kratzer, W., Lichtner, P., Lind, L., Lindström, J., Lobbens, S., Lorentzon, M., Lu, Y., Lyssenko, V., Magnusson, P. K. E., Mahajan, A., Maillard, M., McArdle, W. L., McKenzie, C. A., McLachlan, S., McLaren, P. J., Menni, C., Merger, S., Milani, L., Moayyeri, A., Monda, K. L., Morken, M. A., Müller, G., Müller-Nurasyid, M., Musk, A. W., Narisu, N., Nauck, M., Nolte, I. M., Nöthen, M. M., Oozageer, L., Pilz, S., Rayner, N. W., Renstrom, F., Robertson, N. R., Rose, L. M., Roussel, R., Sanna, S., Scharnagl, H., Scholtens, S., Schumacher, F. R., Schunkert, H., Scott, R. A., Sehmi, J., Seufferlein, T., Shi, J., Silventoinen, K., Smit, J. H., Smith, A. V., Smolonska, J., Stanton, A. V., Stirrups, K., Stott, D. J., Stringham, H. M., Sundström, J., Swertz, M. A., Syvänen, A. C., Tayo, B. O., Thorleifsson, G., Tyrer, J. P., Van Dijk, S., Van Schoor, N. M., Van Der Velde, N., Van Heemst, D., Van Oort, F. V. A., Vermeulen, S. H., Verweij, N., Vonk, J. M., Waite, L. L., Waldenberger, M., Wennauer, R., Wilkens, L. R., Willenborg, C., Wilsgaard, T., Wojczynski, M. K., Wong, A., Wright, A. F., Zhang, Q., Arveiler, D., Bakker, S. J. L., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boomsma, D. I., Bornstein, S. R., Bovet, P., Brambilla, P., Brown, M. J., Campbell, H., Caulfield, M. J., Chakravarti, A., Collins, R., Collins, F. S., Crawford, D. C., Cupples, L. A., Danesh, J., De Faire, U., Den Ruijter, H. M., Erbel, R., Erdmann, J., Eriksson, J. G., Farrall, M., Ferrannini, E., Ferrières, J., Ford, I., Forouhi, N. G., Forrester, T., Gansevoort, R. T., Gejman, P. V., Gieger, C., Golay, A., Gottesman, O., Gudnason, V., Gyllensten, U., Haas, D. W., Hall, A. S., Harris, T. B., Hattersley, A. T., Heath, A. C., Hengstenberg, C., Hicks, A. A., Hindorff, L. A., Hingorani, A. D., Hofman, A., Hovingh, G. K., Humphries, S. E., Hunt, S. C., Hypponen, E., Jacobs, K. B., Jarvelin, M. R., Jousilahti, P., Jula, A. M., Kaprio, J., Kastelein, J. J. P., Kayser, M., Kee, F., Keinanen-Kiukaanniemi, S. M., Kiemeney, L. A., Kooner, J. S., Kooperberg, C., Koskinen, S., Kovacs, P., Kraja, A., Kumari, M., Kuusisto, J., Lakka, T. A., Langenberg, C., Le Marchand, L., Lehtimäki, T., Lupoli, S., Madden, P. A. F., Männistö, S., Manunta, P., Marette, A., Matise, T. C., McKnight, B., Meitinger, T., Moll, F. L., Montgomery, G. W., Morris, A. D., Morris, A. P., Murray, J. C., Nelis, M., Ohlsson, C., Oldehinkel, A. J., Ong, K. K., Ouwehand, W. H., Pasterkamp, G., Peters, A., Pramstaller, P. P., Price, J. F., Qi, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Ritchie, M., Rudan, I., Salomaa, V., Samani, N. J., Saramies, J., Sarzynski, M. A., Schwarz, P. E. H., Sebert, S., Sever, P., Shuldiner, A. R., Sinisalo, J., Steinthorsdottir, V., Stolk, R. P., Tardif, J. C., Tönjes, A., Tremblay, A., Tremoli, E., Virtamo, J., Vohl, M. C., Amouyel, P., Asselbergs, F. W., Assimes, T. L., Bochud, M., Boehm, B. O., Boerwinkle, E., Bottinger, E. P., Bouchard, C., Cauchi, S., Chambers, J. C., Chanock, S. J., Cooper, R. S., De Bakker, P. I. W., Dedoussis, G., Ferrucci, L., Franks, P. W., Froguel, P., Groop, L. C., Haiman, C. A., Hamsten, A., Hayes, M. G., Hui, J., Hunter, D. J., Hveem, K., Jukema, J. W., Kaplan, R. C., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Martin, N. G., März, W., Melbye, M., Moebus, S., Munroe, P. B., Njølstad, I., Oostra, B. A., Palmer, C. N. A., Pedersen, N. L., Perola, M., Pérusse, L., Peters, U., Powell, J. E., Power, C., Quertermous, T., Rauramaa, R., Reinmaa, E., Ridker, P. M., Rivadeneira, F., Rotter, J. I., Saaristo, T. E., Saleheen, D., Schlessinger, D., Slagboom, P. E., Snieder, H., Spector, T. D., Strauch, K., Stumvoll, M., Tuomilehto, J., Uusitupa, M., Van Der Harst, P., Völzke, H., Walker, M., Wareham, N. J., Watkins, H., Wichmann, H. E., Wilson, J. F., Zanen, P., Deloukas, P., Heid, I. M., Lindgren, C. M., Mohlke, K. L., Speliotes, E. K., Thorsteinsdottir, U., Barroso, I., Fox, C. S., North, K. E., Strachan, D. P., Beckmann, J. S., Berndt, S. I., Boehnke, M., Borecki, I. B., McCarthy, M. I., Metspalu, A., Stefansson, K., Uitterlinden, A. G., Van Duijn, C. M., Franke, L., Willer, C. J., Price, A. L., Lettre, G., Loos, R. J. F., Weedon, M. N., Ingelsson, E., O'Connell, J. R., Abecasis, G. R., Chasman, D. I., Goddard, M. E., Visscher, P. M., Hirschhorn, J. N. & Frayling, T. M., Nov 5 2014, In: Nature Genetics. 46, 11, p. 1173-1186 14 p.

    Research output: Contribution to journalArticlepeer-review

    1127 Scopus citations
  • Discrimination between thermodynamic models of cis-regulation using transcription factor occupancy data

    Zeigler, R. D. & Cohen, B. A., Feb 2014, In: Nucleic acids research. 42, 4, p. 2224-2234 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Discriminative motif optimization based on perceptron training

    Patel, R. Y. & Stormo, G. D., Apr 1 2014, In: Bioinformatics. 30, 7, p. 941-948 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    18 Scopus citations
  • Dissecting engineered cell types and enhancing cell fate conversion via Cellnet

    Morris, S. A., Cahan, P., Li, H., Zhao, A. M., San Roman, A. K., Shivdasani, R. A., Collins, J. J. & Daley, G. Q., Aug 14 2014, In: Cell. 158, 4, p. 889-902 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    170 Scopus citations
  • DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease

    the COPDGene and ECLIPSE Investigators, Aug 20 2014, In: Respiratory Research. 15, 1, 97.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line

    Cheverud, J. M., Lawson, H. A., Bouckaert, K., Kossenkov, A. V., Showe, L. C., Cort, L., Blankenhorn, E. P., Bedelbaeva, K., Gourevitch, D., Zhang, Y. & Heber-Katz, E., May 2014, In: Heredity. 112, 5, p. 508-518 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells

    Mollah, S. A., Dobrin, J. S., Feder, R. E., Tse, S. W., Matos, I. G., Cheong, C., Steinman, R. M. & Anandasabapathy, N., 2014, In: Journal of Investigative Dermatology. 134, 5, p. 1265-1275 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    26 Scopus citations
  • Fmr1 and Nlgn3 knockout rats: Novel tools for investigating autism spectrum disorders

    Hamilton, S. M., Green, J. R., Veeraragavan, S., Yuva, L., McCoy, A., Wu, Y., Warren, J., Little, L., Ji, D., Cui, X., Weinstein, E. & Paylor, R., Apr 1 2014, In: Behavioral Neuroscience. 128, 2, p. 103-109 7 p.

    Research output: Contribution to journalArticlepeer-review

    91 Scopus citations
  • FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals

    Qi, Q., Kilpeläinen, T. O., Downer, M. K., Tanaka, T., Smith, C. E., Sluijs, I., Sonestedt, E., Chu, A. Y., Renström, F., Lin, X., Ängquist, L. H., Huang, J., Liu, Z., Li, Y., Asif Ali, M., Xu, M., Ahluwalia, T. S. I., Boer, J. M. A., Chen, P., Daimon, M. & 89 others, Eriksson, J., Perola, M., Friedlander, Y., Gao, Y. T., Heppe, D. H. M., Holloway, J. W., Houston, D. K., Kanoni, S., Kim, Y. M., Laaksonen, M. A., Jääskeläinen, T., Lee, N. R., Lehtimäki, T., Lemaitre, R. N., Lu, W., Luben, R. N., Manichaikul, A., Männistö, S., Marques-Vidal, P., Monda, K. L., Ngwa, J. S., Perusse, L., van Rooij, F. J. A., Xiang, Y. B., Wen, W., Wojczynski, M. K., Zhu, J., Borecki, I. B., Bouchard, C., Cai, Q., Cooper, C., Dedoussis, G. V., Deloukas, P., Ferrucci, L., Forouhi, N. G., Hansen, T., Christiansen, L., Hofman, A., Johansson, I., Jørgensen, T., Karasawa, S., Khaw, K. T., Kim, M. K., Kristiansson, K., Li, H., Lin, X., Liu, Y., Lohman, K. K., Long, J., Mikkilä, V., Mozaffarian, D., North, K., Pedersen, O., Raitakari, O., Rissanen, H., Tuomilehto, J., van der Schouw, Y. T., Uitterlinden, A. G., Zillikens, M. C., Franco, O. H., Shyong Tai, E., Ou Shu, X., Siscovick, D. S., Toft, U., Verschuren, W. M. M., Vollenweider, P., Wareham, N. J., Witteman, J. C. M., Zheng, W., Ridker, P. M., Kang, J. H., Liang, L., Jensen, M. K., Curhan, G. C., Pasquale, L. R., Hunter, D. J., Mohlke, K. L., Uusitupa, M., Cupples, L. A., Rankinen, T., Orho-Melander, M., Wang, T., Chasman, D. I., Franks, P. W., Sørensen, T. I. A., Hu, F. B., Loos, R. J. F., Nettleton, J. A. & Qi, L., Dec 20 2014, In: Human molecular genetics. 23, 25, p. 6961-6972 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    111 Scopus citations
  • Generation and purification of highly specific antibodies for detecting post-translationally modified proteins in vivo

    Arur, S. & Schedl, T., Feb 2014, In: Nature Protocols. 9, 2, p. 375-395 21 p.

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations
  • Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol

    Feitosa, M. F., Wojczynski, M. K., Straka, R., Kammerer, C. M., Lee, J. H., Kraja, A. T., Christensen, K., Newman, A. B., Province, M. A. & Borecki, I. B., 2014, In: Frontiers in Genetics. 5, JUN, Article 159.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations
  • Genetic risk scores associated with baseline lipoprotein subfraction concentrations do not associate with their responses to fenofibrate

    Frazier-Wood, A. C., Wojczynski, M. K., Borecki, I. B., Hopkins, P. N., Lai, C. Q., Ordovas, J. M., Straka, R. J., Tsai, M. Y., Tiwari, H. K. & Arnett, D. K., Aug 25 2014, In: Biology. 3, 3, p. 536-550 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease

    COPDGene and ECLIPSE Investigators, Sep 21 2014, In: Respiratory Research. 15, 1, 113.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    41 Scopus citations
  • Genetic variants associated with lung function: The long life family study

    Thyagarajan, B., Wojczynski, M., Minster, R. L., Sanders, J., Barral, S., Christiansen, L., Barr, R. G. & Newman, A., Nov 1 2014, In: Respiratory Research. 15, 1, 134.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • Genome-wide association analysis identifies six new loci associated with forced vital capacity

    Loth, D. W., Artigas, M. S., Gharib, S. A., Wain, L. V., Franceschini, N., Koch, B., Pottinger, T. D., Smith, A. V., Duan, Q., Oldmeadow, C., Lee, M. K., Strachan, D. P., James, A. L., Huffman, J. E., Vitart, V., Ramasamy, A., Wareham, N. J., Kaprio, J., Wang, X. Q., Trochet, H. & 140 others, Kähönen, M., Flexeder, C., Albrecht, E., Lopez, L. M., De Jong, K., Thyagarajan, B., Alves, A. C., Enroth, S., Omenaas, E., Joshi, P. K., Fall, T., Viñuela, A., Launer, L. J., Loehr, L. R., Fornage, M., Li, G., Wilk, J. B., Tang, W., Manichaikul, A., Lahousse, L., Harris, T. B., North, K. E., Rudnicka, A. R., Hui, J., Gu, X., Lumley, T., Wright, A. F., Hastie, N. D., Campbell, S., Kumar, R., Pin, I., Scott, R. A., Pietiläinen, K. H., Surakka, I., Liu, Y., Holliday, E. G., Schulz, H., Heinrich, J., Davies, G., Vonk, J. M., Wojczynski, M., Pouta, A., Johansson, A., Wild, S. H., Ingelsson, E., Rivadeneira, F., Völzke, H., Hysi, P. G., Eiriksdottir, G., Morrison, A. C., Rotter, J. I., Gao, W., Postma, D. S., White, W. B., Rich, S. S., Hofman, A., Aspelund, T., Couper, D., Smith, L. J., Psaty, B. M., Lohman, K., Burchard, E. G., Uitterlinden, A. G., Garcia, M., Joubert, B. R., McArdle, W. L., Musk, A. B., Hansel, N., Heckbert, S. R., Zgaga, L., Van Meurs, J. B. J., Navarro, P., Rudan, I., Oh, Y. M., Redline, S., Jarvis, D. L., Zhao, J. H., Rantanen, T., O'Connor, G. T., Ripatti, S., Scott, R. J., Karrasch, S., Grallert, H., Gaddis, N. C., Starr, J. M., Wijmenga, C., Minster, R. L., Lederer, D. J., Pekkanen, J., Gyllensten, U., Campbell, H., Morris, A. P., Gläser, S., Hammond, C. J., Burkart, K. M., Beilby, J., Kritchevsky, S. B., Gudnason, V., Hancock, D. B., Williams, O. D., Polasek, O., Zemunik, T., Kolcic, I., Petrini, M. F., Wjst, M., Kim, W. J., Porteous, D. J., Scotland, G., Smith, B. H., Viljanen, A., Heliövaara, M., Attia, J. R., Sayers, I., Hampel, R., Gieger, C., Deary, I. J., Boezen, H. M., Newman, A., Jarvelin, M. R., Wilson, J. F., Lind, L., Stricker, B. H., Teumer, A., Spector, T. D., Melén, E., Peters, M. J., Lange, L. A., Barr, R. G., Bracke, K. R., Verhamme, F. M., Sung, J., Hiemstra, P. S., Cassano, P. A., Sood, A., Hayward, C., Dupuis, J., Hall, I. P., Brusselle, G. G., Tobin, M. D. & London, S. J., Jul 2014, In: Nature Genetics. 46, 7, p. 669-677 9 p.

    Research output: Contribution to journalArticlepeer-review

    98 Scopus citations
  • Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response

    An, P., Straka, R. J., Pollin, T. I., Feitosa, M. F., Wojczynski, M. K., Daw, E. W., O'Connell, J. R., Gibson, Q., Ryan, K. A., Hopkins, P. N., Tsai, M. Y., Lai, C. Q., Province, M. A., Ordovas, J. M., Shuldiner, A. R., Arnett, D. K. & Borecki, I. B., Jul 2014, In: Human genetics. 133, 7, p. 919-930 12 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: The Long Life Family Study (LLFS)

    An, P., Miljkovic, I., Thyagarajan, B., Kraja, A. T., Daw, E. W., Pankow, J. S., Selvin, E., Kao, W. H. L., Maruthur, N. M., Nalls, M. A., Liu, Y., Harris, T. B., Lee, J. H., Borecki, I. B., Christensen, K., Eckfeldt, J. H., Mayeux, R., Perls, T. T., Newman, A. B. & Province, M. A., Apr 2014, In: Metabolism: clinical and experimental. 63, 4, p. 461-468 8 p.

    Research output: Contribution to journalArticlepeer-review

    16 Scopus citations
  • Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of Nitric oxide synthase and Fd59a/Fox-D

    Lacin, H., Rusch, J., Yeh, R. T., Fujioka, M., Wilson, B. A., Zhu, Y., Robie, A. A., Mistry, H., Wang, T., Jaynes, J. B. & Skeath, J. B., Apr 1 2014, In: Developmental Biology. 388, 1, p. 117-133 17 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    19 Scopus citations
  • High-resolution specificity from DNA sequencing highlights alternative modes of lac repressor binding

    Zuo, Z. & Stormo, G. D., Nov 1 2014, In: Genetics. 198, 3, p. 1329-1343 15 p.

    Research output: Contribution to journalArticlepeer-review

    29 Scopus citations
  • High-throughput functional testing of ENCODE segmentation predictions

    Kwasnieski, J. C., Fiore, C., Chaudhari, H. G. & Cohen, B. A., Oct 1 2014, In: Genome research. 24, 10, p. 1595-1602 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    137 Scopus citations
  • Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes

    Visvikis, O., Ihuegbu, N., Labed, S. A., Luhachack, L. G., Alves, A. M. F., Wollenberg, A. C., Stuart, L. M., Stormo, G. D. & Irazoqui, J. E., Jun 19 2014, In: Immunity. 40, 6, p. 896-909 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    172 Scopus citations
  • Investigation of Maternal Genotype Effects in Autism by Genome-Wide Association

    Yuan, H. & Dougherty, J. D., Apr 2014, In: Autism Research. 7, 2, p. 245-253 9 p.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Involvement of Arabidopsis HAC family genes in pleiotropic developmental processes

    Li, C., Xu, J., Li, J., Li, Q. & Yang, H., 2014, In: Plant Signaling and Behavior. 9, MAR, e28173.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • Involvement of arabidopsis histone acetyltransferase HAC family genes in the ethylene signaling pathway

    Li, C., Xu, J., Li, J., Li, Q. & Yang, H., Feb 2014, In: Plant and Cell Physiology. 55, 2, p. 426-435 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    32 Scopus citations
  • Lithium protects against glucocorticoid induced neural progenitor cell apoptosis in the developing cerebellum

    Cabrera, O., Dougherty, J., Singh, S., Swiney, B. S., Farber, N. B. & Noguchi, K. K., Jan 30 2014, In: Brain Research. 1545, p. 54-63 10 p.

    Research output: Contribution to journalArticlepeer-review

    15 Scopus citations
  • Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

    The MAGIC investigators & The GIANT Consortium, Aug 7 2014, In: PLoS genetics. 10, 8, e1004517.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    140 Scopus citations
  • Metabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance

    Beirowski, B., Babetto, E., Golden, J. P., Chen, Y. J., Yang, K., Gross, R. W., Patti, G. J. & Milbrandt, J., Oct 1 2014, In: Nature neuroscience. 17, 10, p. 1351-1361 11 p.

    Research output: Contribution to journalArticlepeer-review

    114 Scopus citations
  • MethylC Track: Visual integration of single-base resolution DNA methylation data on the WashU EpiGenome Browser

    Zhou, X., Li, D., Lowdon, R. F., Costello, J. F. & Wang, T., Aug 1 2014, In: Bioinformatics. 30, 15, p. 2206-2207 2 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • Missense variant in TREML2 protects against Alzheimer's disease

    Benitez, B. A., Jin, S. C., Guerreiro, R., Graham, R., Lord, J., Harold, D., Sims, R., Lambert, J. C., Gibbs, J. R., Bras, J., Sassi, C., Harari, O., Bertelsen, S., Lupton, M. K., Powell, J., Bellenguez, C., Brown, K., Medway, C., Haddick, P. C. G., Van der Brug, M. P. & 22 others, Bhangale, T., Ortmann, W., Behrens, T., Mayeux, R., Pericak-Vance, M. A., Farrer, L. A., Schellenberg, G. D., Haines, J. L., Turton, J., Braae, A., Barber, I., Fagan, A. M., Holtzman, D. M., Morris, J. C., Williams, J., Kauwe, J. S. K., Amouyel, P., Morgan, K., Singleton, A., Hardy, J., Goate, A. M. & Cruchaga, C., Jun 2014, In: Neurobiology of Aging. 35, 6, p. 1510.e19-1510.e26

    Research output: Contribution to journalArticlepeer-review

    Open Access
    84 Scopus citations
  • Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons

    Summers, D. W., DiAntonio, A. & Milbrandt, J., 2014, In: Journal of Neuroscience. 34, 28, p. 9338-9350 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    104 Scopus citations
  • Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans

    Culverhouse, R. C., Johnson, E. O., Breslau, N., Hatsukami, D. K., Sadler, B., Brooks, A. I., Hesselbrock, V. M., Schuckit, M. A., Tischfield, J. A., Goate, A. M., Saccone, N. L. & Bierut, L. J., May 2014, In: Addiction. 109, 5, p. 814-822 9 p.

    Research output: Contribution to journalArticlepeer-review

    25 Scopus citations
  • Open Access
    5 Scopus citations
  • Normal range of bleeding scores for the ISTH-BAT: Adult and pediatric data from the merging project

    Zimmerman Program Investigators, Nov 1 2014, In: Haemophilia. 20, 6, p. 831-835 5 p.

    Research output: Contribution to journalArticlepeer-review

    158 Scopus citations