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  • Neurturin and persephin promote the survival of embryonic basal forebrain cholinergic neurons in vitro

    Golden, J. P., Milbrandt, J. & Johnson, E. M., Nov 2003, In: Experimental Neurology. 184, 1, p. 447-455 9 p.

    Research output: Contribution to journalArticlepeer-review

    22 Scopus citations
  • Neurturin-deficient mice develop dry eye and keratoconjunctivitis sicca

    Song, X. J., Li, D. Q., Farley, W., Luo, L. H., Heuckeroth, R. O., Milbrandt, J. & Pflugfelder, S. C., Oct 1 2003, In: Investigative Ophthalmology and Visual Science. 44, 10, p. 4223-4229 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    98 Scopus citations
  • Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons

    Horger, B. A., Nishimura, M. C., Armanini, M. P., Wang, L. C., Poulsen, K. T., Rosenblad, C., Kirik, D., Moffat, B., Simmons, L., Johnson, E., Milbrandt, J., Rosenthal, A., Bjorklund, A., Vandlen, R. A., Hynes, M. A. & Phillips, H. S., Jul 1 1998, In: Journal of Neuroscience. 18, 13, p. 4929-4937 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    291 Scopus citations
  • Neurturin-mediated ret activation is required for retinal function

    Brantley, M. A., Jain, S., Barr, E. E., Johnson, E. M. & Milbrandt, J., Apr 16 2008, In: Journal of Neuroscience. 28, 16, p. 4123-4135 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons

    Creedon, D. J., Tansey, M. G., Baloh, R. H., Osborne, P. A., Lampe, P. A., Fahrner, T. J., Heuckeroth, R. O., Milbrandt, J. & Johnson, E. M., Jun 24 1997, In: Proceedings of the National Academy of Sciences of the United States of America. 94, 13, p. 7018-7023 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    202 Scopus citations
  • Neurturin signalling via GFRα2 is essential for innervation of glandular but not muscle targets of sacral parasympathetic ganglion neurons

    Wanigasekara, Y., Airaksinen, M. S., Heuckeroth, R. O., Milbrandt, J. & Keast, J. R., Feb 2004, In: Molecular and Cellular Neuroscience. 25, 2, p. 288-300 13 p.

    Research output: Contribution to journalArticlepeer-review

    38 Scopus citations
  • New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

    behalf of the CHARGE EXOME BP, CHD Exome+, Exome BP, GoT2D:T2DGenes Consortia, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group & The Understanding Society Scientific Group, Oct 1 2017, In: Circulation: Cardiovascular Genetics. 10, 5, e001778.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    39 Scopus citations
  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    Dupuis, J., Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., Jackson, A. U., Wheeler, E., Glazer, N. L., Bouatia-Naji, N., Gloyn, A. L., Lindgren, C. M., Mägi, R., Morris, A. P., Randall, J., Johnson, T., Elliott, P., Rybin, D., Thorleifsson, G., Steinthorsdottir, V., Henneman, P., & 283 othersGrallert, H., Dehghan, A., JanHottenga, J., Franklin, C. S., Navarro, P., Song, K., Goel, A., Perry, J. R. B., Egan, J. M., Lajunen, T., Grarup, N., Sparsø, T., Doney, A., Voight, B. F., Stringham, H. M., Li, M., Kanoni, S., Shrader, P., Cavalcanti-Proença, C., Kumari, M., Qi, L., Timpson, N. J., Gieger, C., Zabena, C., Rocheleau, G., Ingelsson, E., An, P., O'Connell, J., Luan, JA., Elliott, A., McCarroll, S. A., Payne, F., Roccasecca, R. M., Pattou, F., Sethupathy, P., Ardlie, K., Ariyurek, Y., Balkau, B., Barter, P., Beilby, J. P., Ben-Shlomo, Y., Benediktsson, R., Bennett, A. J., Bergmann, S., Bochud, M., Boerwinkle, E., Bonnefond, A., Bonnycastle, L. L., Borch-Johnsen, K., Böttcher, Y., Brunner, E., Bumpstead, S. J., Charpentier, G., Der IdaChen, Y., Chines, P., Clarke, R., McOin, L. J., Cooper, M. N., Cornelis, M., Crawford, G., Crisponi, L., Day, I. N. M., De Geus, E. J. C., Delplanque, J., Dina, C., Erdos, M. R., Fedson, A. C., Fischer-Rosinsky, A., Forouhi, N. G., Fox, C. S., Frants, R., GraziaFranzosi, M., Galan, P., Goodarzi, M. O., Graessler, J., Groves, C. J., Grundy, S., Gwilliam, R., Gyllensten, U., Hadjadj, S., Hallmans, G., Hammond, N., Han, X., -LiisaHartikainen, A., Hassanali, N., Hayward, C., Heath, S. C., Hercberg, S., Herder, C., Hicks, A. A., Hillman, D. R., Hingorani, A. D., Hofman, A., Hui, J., Hung, J., Isomaa, B., Johnson, P. R. V., Jørgensen, T., Jula, A., Kaakinen, M., Kaprio, J., AnteroKesaniemi, Y., Kivimaki, M., Knight, B., Koskinen, S., Kovacs, P., Kyvik, K. O., Lathrop, G. M., Lawlor, D. A., Bacquer, O. L., Lecoeur, C., Li, Y., Lyssenko, V., Mahley, R., Mangino, M., Manning, A. K., TeresaMartínez-Larrad, M., McAteer, J. B., McCulloch, L. J., McPherson, R., Meisinger, C., Melzer, D., Meyre, D., Mitchell, B. D., Morken, M. A., Mukherjee, S., Naitza, S., Narisu, N., Neville, M. J., Oostra, B. A., Orrù, M., Pakyz, R., APalmer, C. N., Paolisso, G., Pattaro, C., Pearson, D., Peden, J. F., Pedersen, N. L., Perola, M., Pfeiffer, A. F. H., Pichler, I., Polasek, O., Posthuma, D., Potter, S. C., Pouta, A., Province, M. A., Psaty, B. M., Rathmann, W., Rayner, N. W., Rice, K., Ripatti, S., Rivadeneira, F., Roden, M., Rolandsson, O., Sandbaek, A., Sandhu, M., Sanna, S., Sayer, A. A., Scheet, P., Scott, L. J., Seedorf, U., Sharp, S. J., Shields, B., Sigursson, G., Sijbrands, E. J. G., Silveira, A., Simpson, L., Singleton, A., Smith, N. L., Sovio, U., Swift, A., Syddall, H., -ChristineSyvänen, A., Tanaka, T., Thorand, B., Tichet, J., Tönjes, A., Tuomi, T., Uitterlinden, A. G., Van Dijk, K. W., Hoek, M. V., Varma, D., Visvikis-Siest, S., Vitart, V., Vogelzangs, N., Waeber, G., Wagner, P. J., Walley, A., BragiWalters, G., Ward, K. L., Watkins, H., Weedon, M. N., Wild, S. H., Willemsen, G., MWitteman, J. C., GYarnell, J. W., Zeggini, E., Zelenika, D., Zethelius, B., Zhai, G., Zhao, J. H., Zillikens, M. C., Borecki, I. B., Loos, R. J. F., Meneton, P., Magnusson, P. K. E., Nathan, D. M., Williams, G. H., Hattersley, A. T., Silander, K., Salomaa, V., Smith, G. D., Bornstein, S. R., Schwarz, P., Spranger, J., Karpe, F., Shuldiner, A. R., Cooper, C., Dedoussis, G. V., Serrano-Ríos, M., Morris, A. D., Lind, L., Palmer, L. J., Hu, F. B., Franks, P. W., Ebrahim, S., Marmot, M., Linda Kao, W. H., Pankow, J. S., Sampson, M. J., Kuusisto, J., Laakso, M., Hansen, T., Pedersen, O., Pramstaller, P. P., Wichmann, H. E., Illig, T., Rudan, I., Wright, A. F., Stumvoll, M., Campbell, H., Wilson, J. F., Bergman, R. N., Buchanan, T. A., Collins, F. S., Mohlke, K. L., Tuomilehto, J., Valle, T. T., Altshuler, D., Rotter, J. I., Siscovick, D. S., Penninx, B. W. J. H., Boomsma, D. I., Deloukas, P., Spector, T. D., Frayling, T. M., Ferrucci, L., Kong, A., Thorsteinsdottir, U., Stefansson, K., Van Duijn, C. M., Aulchenko, Y. S., Cao, A., Scuteri, A., Schlessinger, D., Uda, M., Ruokonen, A., -RiittaJarvelin, M., Waterworth, D. M., Vollenweider, P., Peltonen, L., Mooser, V., Abecasis, G. R., Wareham, N. J., Sladek, R., Froguel, P., Watanabe, R. M., Meigs, J. B., Groop, L., Boehnke, M., McCarthy, M. I., Florez, J. C. & Barroso, I., Feb 2010, In: Nature Genetics. 42, 2, p. 105-116 12 p.

    Research output: Contribution to journalArticlepeer-review

    1597 Scopus citations
  • New genetic loci link adipose and insulin biology to body fat distribution

    ADIPOGen Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium; GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen Consortium, Feb 12 2015, In: Nature. 518, 7538, p. 187-196 10 p.

    Research output: Contribution to journalArticlepeer-review

    844 Scopus citations
  • New loci associated with kidney function and chronic kidney disease

    Köttgen, A., Pattaro, C., Böger, C. A., Fuchsberger, C., Olden, M., Glazer, N. L., Parsa, A., Gao, X., Yang, Q., Smith, A. V., O'Connel, J. R., Li, M., Schmidt, H., Tanaka, T., Isaacs, A., Ketkar, S., Hwang, S. J., Johnson, A. D., Dehghan, A., Teumer, A., & 112 othersParé, G., Atkinson, E. J., Zeller, T., Lohman, K., Cornelis, M. C., Probst-Hensch, N. M., Kronenberg, F., Tönjes, A., Hayward, C., Aspelund, T., Eiriksdottir, G., Launer, L. J., Harris, T. B., Rampersaud, E., Mitchel, B. D., Arking, D. E., Boerwinkle, E., Struchalin, M., Cavalieri, M., Singleton, A., Giallauria, F., Metter, J., De Boer, I. H., Haritunians, T., Lumley, T., Siscovick, D., Psaty, B. M., CarolaZillikens, M., Oostra, B. A., Feitosa, M., Province, M., Andrade, M. D., Turner, S. T., Schillert, A., Ziegler, A., Wild, P. S., Schnabel, R. B., Wilde, S., Munzel, T. F., Leak, T. S., Illig, T., Klopp, N., Meisinger, C., Wichmann, H. E., Koenig, W., Zgaga, L., Zemunik, T., Kolcic, I., Minelli, C., Hu, F. B., Johansson, Å., Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Schreiber, S., Aulchenko, Y. S., Felix, J. F., Rivadeneira, F., Uitterlinden, A. G., Hofman, A., Imboden, M., Nitsch, D., Brandstätter, A., Kollerits, B., Kedenko, L., Mägi, R., Stumvoll, M., Kovacs, P., Boban, M., Campbell, S., Endlich, K., Völzke, H., Kroemer, H. K., Nauck, M., Völker, U., Polasek, O., Vitart, V., Badola, S., Parker, A. N., Ridker, P. M., Kardia, S. L. R., Blankenberg, S., Liu, Y., Curhan, G. C., Franke, A., Rochat, T., Paulweber, B., Prokopenko, I., Wang, W., Gudnason, V., Shuldine, A. R., Coresh, J., Schmidt, R., Ferrucci, L., Shlipak, M. G., Van Duijn, C. M., Borecki, I., Krämer, B. K., Rudan, I., Gyllensten, U., Wilson, J. F., Witteman, J. C., Pramstaller, P. P., Rettig, R., Hastie, N., Chasman, D. I., Kao, W. H., Heid, I. M. & Fox, C. S., May 2010, In: Nature Genetics. 42, 5, p. 376-384 9 p.

    Research output: Contribution to journalArticlepeer-review

    608 Scopus citations
  • New mutations in flagellar motors identified by whole genome sequencing in Chlamydomonas

    Lin, H., Nauman, N. P., Albee, A. J., Hsu, S. & Dutcher, S. K., Oct 30 2013, In: Cilia. 2, 1, 14.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    20 Scopus citations
  • New neuroblast markers and the origin of the aCC/pCC neurons in the Drosophila central nervous system

    Broadus, J., Skeath, J. B., Spana, E. P., Bossing, T., Technau, G. & Doe, C. Q., Nov 1995, In: Mechanisms of Development. 53, 3, p. 393-402 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    176 Scopus citations
  • Next generation analytic tools for large scale genetic epidemiology studies of complex diseases

    Mechanic, L. E., Chen, H. S., Amos, C. I., Chatterjee, N., Cox, N. J., Divi, R. L., Fan, R., Harris, E. L., Jacobs, K., Kraft, P., Leal, S. M., McAllister, K., Moore, J. H., Paltoo, D. N., Province, M. A., Ramos, E. M., Ritchie, M. D., Roeder, K., Schaid, D. J., Stephens, M., & 7 othersThomas, D. C., Weinberg, C. R., Witte, J. S., Zhang, S., Zöllner, S., Feuer, E. J. & Gillanders, E. M., Jan 2012, In: Genetic Epidemiology. 36, 1, p. 22-35 14 p.

    Research output: Contribution to journalArticlepeer-review

    49 Scopus citations
  • NFκB-inducing kinase inhibits NFκB activity specifically in neurons of the CNS

    Mao, X., Phanavanh, B., Hamdan, H., Moerman-Herzog, A. M. & Barger, S. W., Apr 2016, In: Journal of Neurochemistry. 137, 2, p. 154-163 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • NGF augments the autophosphorylation of Ret via inhibition of ubiquitin-dependent degradation

    Pierchala, B. A., Tsui, C. C., Milbrandt, J. & Johnson, E. M., Mar 2007, In: Journal of Neurochemistry. 100, 5, p. 1169-1176 8 p.

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations
  • NGF utilizes c-Ret via a novel GFL-independent, inter-RTK signaling mechanism to maintain the trophic status of mature sympathetic neurons

    Tsui-Pierchala, B. A., Milbrandt, J. & Johnson, E. M., Jan 17 2002, In: Neuron. 33, 2, p. 261-273 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    97 Scopus citations
  • NHLBI Family Blood Pressure Program: Methodology and recruitment in the HyperGEN Network

    Williams, R. R., Rao, D. C., Ellison, R. C., Arnett, D. K., Heiss, G., Oberman, A., Eckfeldt, J. H., Leppert, M. F., Province, M. A., Mockrin, S. C. & Hunt, S. C., Aug 2000, In: Annals of Epidemiology. 10, 6, p. 389-400 12 p.

    Research output: Contribution to journalArticlepeer-review

    144 Scopus citations
  • NHLBI Family Heart Study: Objectives and design

    Higgins, M., Province, M., Heiss, G., Eckfeldt, J., Curtis Ellison, R., Folsom, A. R., Rao, D. C., Sprafka, J. M. & Williams, R., Jun 15 1996, In: American journal of epidemiology. 143, 12, p. 1219-1228 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    240 Scopus citations
  • NIA Long Life Family Study: Objectives, Design, and Heritability of Cross-Sectional and Longitudinal Phenotypes

    Wojczynski, M. K., Jiuan Lin, S., Sebastiani, P., Perls, T. T., Lee, J., Kulminski, A., Newman, A., Zmuda, J. M., Christensen, K. & Province, M. A., Apr 1 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 4, p. 717-727 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Nicotinamide adenine dinucleotide (NAD)-regulated DNA methylation alters CCCTC-binding factor (CTCF)/cohesin binding and transcription at the BDNF locus

    Chang, J., Zhang, B., Heath, H., Galjart, N., Wang, X. & Milbrandt, J., Dec 14 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 50, p. 21836-21841 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    40 Scopus citations
  • Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxic-necrotic cell death

    Verghese, P. B., Sasaki, Y., Yang, D., Stewart, F., Sabar, F., Finn, M. B., Wroge, C. M., Mennerick, S., Neil, J. J., Milbrandt, J. & Holtzman, D. M., Nov 22 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 47, p. 19054-19059 6 p.

    Research output: Contribution to journalArticlepeer-review

    46 Scopus citations
  • Open Access
    179 Scopus citations
  • Nicotinamide mononucleotide adenylyltransferase promotes hypoxic survival by activating the mitochondrial unfolded protein response

    Mao, X. R., Kaufman, D. M. & Crowder, C. M., 2016, In: Cell Death and Disease. 7, 2, e2113.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    15 Scopus citations
  • Nicotine dependence and comorbid psychiatric disorders: Examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes

    Chen, L. S., Xian, H., Grucza, R. A., Saccone, N. L., Wang, J. C., Johnson, E. O., Breslau, N., Hatsukami, D. & Bierut, L. J., Jun 2012, In: Drug and Alcohol Dependence. 123, SUPPL.1, p. S42-S51

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain

    Teitelbaum, A. M., Murphy, S. E., Akk, G., Baker, T. B., Germann, A., Von Weymarn, L. B., Bierut, L. J., Goate, A., Kharasch, E. D. & Bloom, A. J., Jan 1 2018, In: Pharmacogenomics Journal. 18, 1, p. 136-143 8 p.

    Research output: Contribution to journalArticlepeer-review

    10 Scopus citations
  • Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes

    Bloom, A. J., Wang, P. F. & Kharasch, E. D., Apr 2019, In: Pharmacology Research and Perspectives. 7, 2, e00468.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection

    Sasaki, Y., Zhu, J., Shi, Y., Gu, W., Kobe, B., Ve, T., DiAntonio, A. & Milbrandt, J., Nov 2021, In: Experimental Neurology. 345, 113842.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth

    Araki, T. & Milbrandt, J., Aug 1996, In: Neuron. 17, 2, p. 353-361 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    161 Scopus citations
  • Ninjurin2, a novel homophilic adhesion molecule, is expressed in mature sensory and enteric neurons and promotes neurite outgrowth

    Araki, T. & Milbrandt, J., Jan 1 2000, In: Journal of Neuroscience. 20, 1, p. 187-195 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    107 Scopus citations
  • NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+depletion

    Sasaki, Y., Nakagawa, T., Mao, X., DiAntonio, A. & Milbrandt, J., Oct 13 2016, In: eLife. 5, OCTOBER2016, e19749.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    118 Scopus citations
  • Nmnat1 protects neuronal function without altering phospho-tau pathology in a mouse model of tauopathy

    Musiek, E. S., Xiong, D. D., Patel, T., Sasaki, Y., Wang, Y., Bauer, A. Q., Singh, R., Finn, S. L., Culver, J. P., Milbrandt, J. & Holtzman, D. M., Jun 1 2016, In: Annals of Clinical and Translational Neurology. 3, 6, p. 434-442 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    15 Scopus citations
  • NMNAT3 is protective against the effects of neonatal cerebral hypoxia-ischemia

    Galindo, R., Banks Greenberg, M., Araki, T., Sasaki, Y., Mehta, N., Milbrandt, J. & Holtzman, D. M., Oct 2017, In: Annals of Clinical and Translational Neurology. 4, 10, p. 722-738 17 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress

    Press, C. & Milbrandt, J., May 7 2008, In: Journal of Neuroscience. 28, 19, p. 4861-4871 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    119 Scopus citations
  • No evidence of linkage between the very-low-density lipoprotein receptor gene and fasting serum insulin or homeostasis model assessment insulin resistance index: The National Heart, Lung, and Blood Institute Family Heart Study

    Hong, Y., Leppert, M. F., Lin, J., Hunt, S. C., Rich, S. S., Arnett, D. K., Myers, R. H., Eckfeldt, J., Williams, R. R. & Province, M. A., 2000, In: Metabolism: clinical and experimental. 49, 3, p. 293-297 5 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • No linkage of the lipoprotein lipase locus to hypertension in Caucasians

    Hunt, S. C., Province, M. A., Atwood, L. D., Sholinsky, P., Lalouel, J. M., Rao, D. C., Williams, R. R. & Leppert, M. F., 1999, In: Journal of Hypertension. 17, 1, p. 39-43 5 p.

    Research output: Contribution to journalArticlepeer-review

    16 Scopus citations
  • Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human

    Leparc, G. G. & Mitra, R. D., May 2007, In: Nucleic acids research. 35, 10, p. 3192-3202 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • Non-independence of Mnt repressor-operator interaction determined by a new quantitative multiple fluorescence relative affinity (QuMFRA) assay

    Man, T. K. & Stormo, G. D., Jun 15 2001, In: Nucleic acids research. 29, 12, p. 2471-2478 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    156 Scopus citations
  • Normal range of bleeding scores for the ISTH-BAT: Adult and pediatric data from the merging project

    Zimmerman Program Investigators, Nov 1 2014, In: Haemophilia. 20, 6, p. 831-835 5 p.

    Research output: Contribution to journalArticlepeer-review

    163 Scopus citations
  • Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index

    Generation Scotland Consortium, The LifeLines Cohort study & The GIANT Consortium, Jan 1 2014, In: PLoS genetics. 10, 7, p. 1-12 12 p., e1004508.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    41 Scopus citations
  • Novel chemo-sensitizing agent, ERW1227B, impairs cellular motility and enhances cell death in glioblastomas

    Yuan, L., Holmes, T. C., Watts, R. E., Khosla, C., Broekelmann, T. J., Mecham, R., Zheng, H., Izaguirre, E. W. & Rich, K. M., Jun 2011, In: Journal of Neuro-Oncology. 103, 2, p. 207-219 13 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Novel genes identified in a high-density genome wide association study for nicotine dependence

    Bierut, L. J., Madden, P. A. F., Breslau, N., Johnson, E. O., Hatsukami, D., Pomerleau, O. F., Swan, G. E., Rutter, J., Bertelsen, S., Fox, L., Fugman, D., Goate, A. M., Hinrichs, A. L., Konvicka, K., Martin, N. G., Montgomery, G. W., Saccone, N. L., Saccone, S. F., Wang, J. C., Chase, G. A., & 2 othersRice, J. P. & Ballinger, D. G., Jan 1 2007, In: Human molecular genetics. 16, 1, p. 24-35 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    498 Scopus citations
  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Feitosa, M. F., Kraja, A. T., Chasman, D. I., Sung, Y. J., Winkler, T. W., Ntalla, I., Guo, X., Franceschini, N., Cheng, C. Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Bentley, A. R., Brown, M. R., Schwander, K., Richard, M. A., Noordam, R., Aschard, H., & 252 othersBartz, T. M., Bielak, L. F., Dorajoo, R., Fisher, V., Hartwig, F. P., Horimoto, A. R. V. R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Wojczynski, M. K., Alver, M., Boissel, M., Cai, Q., Campbell, A., Chai, J. F., Chen, X., Divers, J., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., He, M., Hsu, F. C., Jackson, A. U., Kähönen, M., Kasturiratne, A., Komulainen, P., Kühnel, B., Laguzzi, F., Luan, JA., Matoba, N., Nolte, I. M., Padmanabhan, S., Riaz, M., Rueedi, R., Robino, A., Said, M. A., Scott, R. A., Sofer, T., Stančáková, A., Takeuchi, F., Tayo, B. O., Van Der Most, P. J., Varga, T. V., Vitart, V., Wang, Y., Ware, E. B., Warren, H. R., Weiss, S., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Amin, N., Amini, M., Arking, D. E., Aung, T., Boerwinkle, E., Borecki, I., Broeckel, U., Brown, M., Brumat, M., Burke, G. L., Canouil, M., Chakravarti, A., Charumathi, S., Chen, Y. D. I., Connell, J. M., Correa, A., De Las Fuentes, L., De Mutsert, R., De Silva, H. J., Deng, X., Ding, J., Duan, Q., Eaton, C. B., Ehret, G., Eppinga, R. N., Evangelou, E., Faul, J. D., Felix, S. B., Forouhi, N. G., Forrester, T., Franco, O. H., Friedlander, Y., Gandin, I., Gao, H., Ghanbari, M., Gigante, B., Gu, C. C., Gu, D., Hagenaars, S. P., Hallmans, G., Harris, T. B., He, J., Heikkinen, S., Heng, C. K., Hirata, M., Howard, B. V., Ikram, M. A., John, U., Katsuya, T., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Krieger, J. E., Kritchevsky, S. B., Kubo, M., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lehne, B., Lewis, C. E., Li, Y., Lin, S., Liu, J., Liu, J., Loh, M., Louie, T., Mägi, R., McKenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mohlke, K. L., Momozawa, Y., Nalls, M. A., Nelson, C. P., Sotoodehnia, N., Norris, J. M., O'Connell, J. R., Palmer, N. D., Perls, T., Pedersen, N. L., Peters, A., Peyser, P. A., Poulter, N., Raffel, L. J., Raitakari, O. T., Roll, K., Rose, L. M., Rosendaal, F. R., Rotter, J. I., Schmidt, C. O., Schreiner, P. J., Schupf, N., Scott, W. R., Sever, P. S., Shi, Y., Sidney, S., Sims, M., Sitlani, C. M., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Stringham, H. M., Tan, N. Y. Q., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Turner, S. T., Uitterlinden, A. G., Vollenweider, P., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Williams, C., Yao, J., Yu, C., Yuan, J. M., Zhao, W., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Deary, I. J., Esko, T., Farrall, M., Franks, P. W., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Jonas, J. B., Kamatani, Y., Kato, N., Kooner, J. S., Kutalik, Z., Laakso, M., Laurie, C. C., Leander, K., Lehtimäki, T., Magnusson, P. K. E., Oldehinkel, A. J., Penninx, B. W. J. H., Polasek, O., Porteous, D. J., Rauramaa, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Weir, D. R., Wickremasinghe, A. R., Wu, T., Zheng, W., Bouchard, C., Christensen, K., Evans, M. K., Gudnason, V., Horta, B. L., Kardia, S. L. R., Liu, Y., Pereira, A. C., Psaty, B. M., Ridker, P. M., Van Dam, R. M., Gauderman, W. J., Zhu, X., Mook-Kanamori, D. O., Fornage, M., Rotimi, C. N., Cupples, L. A., Kelly, T. N., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Kooperberg, C., Palmas, W., Rice, K., Morrison, A. C., Elliott, P., Caulfield, M. J., Munroe, P. B., Rao, D. C., Province, M. A. & Levy, D., Jun 2018, In: PloS one. 13, 6, e0198166.

    Research output: Contribution to journalArticlepeer-review

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    35 Scopus citations
  • Novel genetic locus implicated for HIV-1 acquisition with putative regulatory links to HIV replication and infectivity: A genome-wide association study

    Johnson, E. O., Hancock, D. B., Gaddis, N. C., Levy, J. L., Page, G., Novak, S. P., Glasheen, C., Saccone, N. L., Rice, J. P., Moreau, M. P., Doheny, K. F., Romm, J. M., Brooks, A. I., Aouizerat, B. E., Bierut, L. J. & Kral, A. H., Mar 18 2015, In: PloS one. 10, 3, e0118149.

    Research output: Contribution to journalArticlepeer-review

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    17 Scopus citations
  • Novel LC8 mutations have disparate effects on the assembly and stability of flagellar complexes

    Yang, P., Yang, C., Wirschell, M. & Davis, S., Nov 6 2009, In: Journal of Biological Chemistry. 284, 45, p. 31412-31421 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    15 Scopus citations
  • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals

    Dastani, Z., Hivert, M. F., Timpson, N., Perry, J. R. B., Yuan, X., Scott, R. A., Henneman, P., Heid, I. M., Kizer, J. R., Lyytikäinen, L. P., Fuchsberger, C., Tanaka, T., Morris, A. P., Small, K., Isaacs, A., Beekman, M., Coassin, S., Lohman, K., Qi, L., Kanoni, S., & 528 othersPankow, J. S., Uh, H. W., Wu, Y., Bidulescu, A., Rasmussen-Torvik, L. J., Greenwood, C. M. T., Ladouceur, M., Grimsby, J., Manning, A. K., Liu, C. T., Kooner, J., Mooser, V. E., Vollenweider, P., Kapur, K. A., Chambers, J., Wareham, N. J., Langenberg, C., Frants, R., Willems-VanDijk, K., Oostra, B. A., Willems, S. M., Lamina, C., Winkler, T. W., Psaty, B. M., Tracy, R. P., Brody, J., Chen, I., Viikari, J., Kähönen, M., Pramstaller, P. P., Evans, D. M., St. Pourcain, B., Sattar, N., Wood, A. R., Bandinelli, S., Carlson, O. D., Egan, J. M., Böhringer, S., van Heemst, D., Kedenko, L., Kristiansson, K., Nuotio, M. L., Loo, B. M., Harris, T., Garcia, M., Kanaya, A., Haun, M., Klopp, N., Wichmann, H. E., Deloukas, P., Katsareli, E., Couper, D. J., Duncan, B. B., Kloppenburg, M., Adair, L. S., Borja, J. B., Florez, J. C., MAGIC Consortium, C., GLGC Investigators, I., MuTHER Consortium, C., Wilson, J. G., Musani, S., Guo, X., Johnson, T., Semple, R., Teslovich, T. M., Redline, S., Buxbaum, S. G., Mohlke, K. L., Meulenbelt, I., Ballantyne, C. M., Dedoussis, G. V., Hu, F. B., Liu, Y., Paulweber, B., Spector, T. D., Slagboom, P. E., Ferrucci, L., Jula, A., Perola, M., Raitakari, O., Salomaa, V., Eriksson, J. G., Frayling, T. M., Hicks, A. A., Lehtimäki, T., Smith, G. D., Siscovick, D. S., Kronenberg, F., van Duijn, C., Loos, R. J. F., Waterworth, D. M., Meigs, J. B., Meigs, J. B., Richards, J. B., Voight, B. F., Scott, L. J., Steinthorsdottir, V., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Hofmann, O. M., Segrè, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Boström, K. B., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Fox, C. S., Franklin, C. S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Isomaa, B., Jackson, A. U., Johnson, P. R. V., Jørgensen, T., Kao, W. H. L., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M. A., Narisu, N., Nilsson, P., Owen, K. R., Payne, F., Petersen, A. K., Platou, C., Proenca, C., Prokopenko, I., Rathmann, W., Rayner, N. W., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. 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A., Kastelein, J. J. P., Schadt, E. E., Strachan, D. P., Reilly, M. P., Samani, N. J., Schunkert, H., Cupples, L. A., Sandhu, M. S., Ridker, P. M. & Munroe, P. B., Mar 29 2012, In: PLoS genetics. 8, 3, e1002607.

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    322 Scopus citations
  • Novel markers of gonadectomy-induced adrenocortical neoplasia in the mouse and ferret

    Schillebeeckx, M., Pihlajoki, M., Gretzinger, E., Yang, W., Thol, F., Hiller, T., Löbs, A. K., Röhrig, T., Schrade, A., Cochran, R., Jay, P. Y., Heikinheimo, M., Mitra, R. D. & Wilson, D. B., Jan 5 2015, In: Molecular and Cellular Endocrinology. 399, p. 122-130 9 p.

    Research output: Contribution to journalArticlepeer-review

    20 Scopus citations
  • Novel Modeling of Combinatorial miRNA Targeting Identifies SNP with Potential Role in Bone Density

    Coronnello, C., Hartmaier, R., Arora, A., Huleihel, L., Pandit, K. V., Bais, A. S., Butterworth, M., Kaminski, N., Stormo, G. D., Oesterreich, S. & Benos, P. V., Dec 2012, In: PLoS computational biology. 8, 12, e1002830.

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    33 Scopus citations
  • Novel mutants of NAB corepressors enhance activation by Egr transactivators

    Svaren, J., Sevetson, B. R., Golda, T., Stanton, J. J., Swirnoff, A. H. & Milbrandt, J., Oct 15 1998, In: EMBO Journal. 17, 20, p. 6010-6019 10 p.

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    Open Access
    66 Scopus citations
  • Novel sequence-based method for identifying transcription factor binding sites in prokaryotic genomes

    Sahota, G. & Stormo, G. D., Nov 2010, In: Bioinformatics. 26, 21, p. 2672-2677 6 p., btq501.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • Novel transcription regulatory elements in Caenorhabditis elegans muscle genes

    GuhaThakurta, D., Schriefer, L. A., Waterston, R. H. & Stormo, G. D., Dec 2004, In: Genome research. 14, 12, p. 2457-2468 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    21 Scopus citations