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  • Genome-wide association study and linkage analysis of the healthy aging index

    Minster, R. L., Sanders, J. L., Singh, J., Kammerer, C. M., Barmada, M. M., Matteini, A. M., Zhang, Q., Wojczynski, M. K., Daw, E. W., Brody, J. A., Arnold, A. M., Lunetta, K. L., Murabito, J. M., Christensen, K., Perls, T. T., Province, M. A. & Newman, A. B., Aug 2015, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 70, 8, p. 1003-1008 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Scopus citations

  • Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction

    Odonnell, C. J., Kavousi, M., Smith, A. V., Kardia, S. L. R., Feitosa, M. F., Hwang, S. J., Sun, Y. V., Province, M. A., Aspelund, T., Dehghan, A., Hoffmann, U., Bielak, L. F., Zhang, Q., Eiriksdottir, G., Van Duijn, C. M., Fox, C. S., De Andrade, M., Kraja, A. T., Sigurdsson, S., Elias-Smale, S. E., & 47 othersMurabito, J. M., Launer, L. J., Van Der Lugt, A., Kathiresan, S., Krestin, G. P., Herrington, D. M., Howard, T. D., Liu, Y., Post, W., Mitchell, B. D., Oconnell, J. R., Shen, H., Shuldiner, A. R., Altshuler, D., Elosua, R., Salomaa, V., Schwartz, S. M., Siscovick, D. S., Voight, B. F., Bis, J. C., Glazer, N. L., Psaty, B. M., Boerwinkle, E., Heiss, G., Blankenberg, S., Zeller, T., Wild, P. S., Schnabel, R. B., Schillert, A., Ziegler, A., Münzel, T. F., White, C. C., Rotter, J. I., Nalls, M., Oudkerk, M., Johnson, A. D., Newman, A. B., Uitterlinden, A. G., Massaro, J. M., Cunningham, J., Harris, T. B., Hofman, A., Peyser, P. A., Borecki, I. B., Cupples, L. A., Gudnason, V. & Witteman, J. C. M., Dec 20 2011, In: Circulation. 124, 25, p. 2855-2864 10 p.

    Research output: Contribution to journal › Article › peer-review

    237 Scopus citations

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G. B., Emilsson, V., Meddens, S. F. W., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P., De Vlaming, R., Abdellaoui, A., Ahluwalia, T. S., Bacelis, J., Baumbach, C., Bjornsdottir, G., & 235 othersBrandsma, J. H., Pina Concas, M., Derringer, J., Furlotte, N. A., Galesloot, T. E., Girotto, G., Gupta, R., Hall, L. M., Harris, S. E., Hofer, E., Horikoshi, M., Huffman, J. E., Kaasik, K., Kalafati, I. P., Karlsson, R., Kong, A., Lahti, J., Van Der Lee, S. J., Deleeuw, C., Lind, P. A., Lindgren, K. O., Liu, T., Mangino, M., Marten, J., Mihailov, E., Miller, M. B., Van Der Most, P. J., Oldmeadow, C., Payton, A., Pervjakova, N., Peyrot, W. J., Qian, Y., Raitakari, O., Rueedi, R., Salvi, E., Schmidt, B., Schraut, K. E., Shi, J., Smith, A. V., Poot, R. A., St Pourcain, B., Teumer, A., Thorleifsson, G., Verweij, N., Vuckovic, D., Wellmann, J., Westra, H. J., Yang, J., Zhao, W., Zhu, Z., Alizadeh, B. Z., Amin, N., Bakshi, A., Baumeister, S. E., Biino, G., Bønnelykke, K., Boyle, P. A., Campbell, H., Cappuccio, F. P., Davies, G., De Neve, J. E., Deloukas, P., Demuth, I., Ding, J., Eibich, P., Eisele, L., Eklund, N., Evans, D. M., Faul, J. D., Feitosa, M. F., Forstner, A. J., Gandin, I., Gunnarsson, B., Halldórsson, B. V., Harris, T. B., Holliday, E. G., Heath, A. C., Hocking, L. J., Homuth, G., Horan, M. A., Hottenga, J. J., De Jager, P. L., Joshi, P. K., Jugessur, A., Kaakinen, M. A., Kähönen, M., Kanoni, S., Keltigangas-Järvinen, L., Kiemeney, L. A. L. M., Kolcic, I., Koskinen, S., Kraja, A. T., Kroh, M., Kutalik, Z., Latvala, A., Launer, L. J., Lebreton, M. P., Levinson, D. F., Lichtenstein, P., Lichtner, P., Liewald, D. C. M., Loukola, A., Madden, P. A., Mägi, R., Mäki-Opas, T., Marioni, R. E., Marques-Vidal, P., Meddens, G. A., Mcmahon, G., Meisinger, C., Meitinger, T., Milaneschi, Y., Milani, L., Montgomery, G. W., Myhre, R., Nelson, C. P., Nyholt, D. R., Ollier, W. E. R., Palotie, A., Paternoster, L., Pedersen, N. L., Petrovic, K. E., Porteous, D. J., Raïkkönen, K., Ring, S. M., Robino, A., Rostapshova, O., Rudan, I., Rustichini, A., Salomaa, V., Sanders, A. R., Sarin, A. P., Schmidt, H., Scott, R. J., Smith, B. H., Smith, J. A., Staessen, J. A., Steinhagen-Thiessen, E., Strauch, K., Terracciano, A., Tobin, M. D., Ulivi, S., Vaccargiu, S., Quaye, L., Van Rooij, F. J. A., Venturini, C., Vinkhuyzen, A. A. E., Völker, U., Völzke, H., Vonk, J. M., Vozzi, D., Waage, J., Ware, E. B., Willemsen, G., Attia, J. R., Bennett, D. A., Berger, K., Bertram, L., Bisgaard, H., Boomsma, D. I., Borecki, I. B., Bültmann, U., Chabris, C. F., Cucca, F., Cusi, D., Deary, I. J., Dedoussis, G. V., Van Duijn, C. M., Eriksson, J. G., Franke, B., Franke, L., Gasparini, P., Gejman, P. V., Gieger, C., Grabe, H. J., Gratten, J., Groenen, P. J. F., Gudnason, V., Van Der Harst, P., Hayward, C., Hinds, D. A., Hoffmann, W., Hyppönen, E., Iacono, W. G., Jacobsson, B., Järvelin, M. R., Jöckel, K. H., Kaprio, J., Kardia, S. L. R., Lehtimäki, T., Lehrer, S. F., Magnusson, P. K. E., Martin, N. G., Mcgue, M., Metspalu, A., Pendleton, N., Penninx, B. W. J. H., Perola, M., Pirastu, N., Pirastu, M., Polasek, O., Posthuma, D., Power, C., Province, M. A., Samani, N. J., Schlessinger, D., Schmidt, R., Sørensen, T. I. A., Spector, T. D., Stefansson, K., Thorsteinsdottir, U., Thurik, A. R., Timpson, N. J., Tiemeier, H., Tung, J. Y., Uitterlinden, A. G., Vitart, V., Vollenweider, P., Weir, D. R., Wilson, J. F., Wright, A. F., Conley, D. C., Krueger, R. F., Davey Smith, G., Hofman, A., Laibson, D. I., Medland, S. E., Meyer, M. N., Yang, J., Johannesson, M., Visscher, P. M., Esko, T., Koellinger, P. D., Cesarini, D. & Benjamin, D. J., May 11 2016, In: Nature. 533, 7604, p. 539-542 4 p.

    Research output: Contribution to journal › Article › peer-review

    754 Scopus citations

  • Genome-wide association study identifies a novel locus for cannabis dependence

    Agrawal, A., Chou, Y. L., Carey, C. E., Baranger, D. A. A., Zhang, B., Sherva, R., Wetherill, L., Kapoor, M., Wang, J. C., Bertelsen, S., Anokhin, A. P., Hesselbrock, V., Kramer, J., Lynskey, M. T., Meyers, J. L., Nurnberger, J. I., Rice, J. P., Tischfield, J., Bierut, L. J., Degenhardt, L., & 16 othersFarrer, L. A., Gelernter, J., Hariri, A. R., Heath, A. C., Kranzler, H. R., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Porjesz, B., Wang, T., Whitfield, J. B., Edenberg, H. J., Foroud, T., Goate, A. M., Bogdan, R. & Nelson, E. C., May 1 2018, In: Molecular Psychiatry. 23, 5, p. 1293-1302 10 p.

    Research output: Contribution to journal › Article › peer-review

    30 Scopus citations

  • Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: The Long Life Family Study (LLFS)

    An, P., Miljkovic, I., Thyagarajan, B., Kraja, A. T., Daw, E. W., Pankow, J. S., Selvin, E., Kao, W. H. L., Maruthur, N. M., Nalls, M. A., Liu, Y., Harris, T. B., Lee, J. H., Borecki, I. B., Christensen, K., Eckfeldt, J. H., Mayeux, R., Perls, T. T., Newman, A. B. & Province, M. A., Apr 2014, In: Metabolism: clinical and experimental. 63, 4, p. 461-468 8 p.

    Research output: Contribution to journal › Article › peer-review

    19 Scopus citations

  • Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

    Alcohol Genome-wide Association (AlcGen) Consortium; Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study; Genetic Investigation of Anthropometric Traits (GIANT) Consortium; Global Lipids Genetics Consortium; Genetics of Liver Disease (GOLD) Consortium; International Consortium for Blood Pressure (ICBP-GWAS); Meta-analyses of Glucose and Insulin-Related Traits Consortium (MAGIC) & Collaborators, Nov 1 2011, In: Nature Genetics. 43, 11, p. 1131-1138 8 p.

    Research output: Contribution to journal › Article › peer-review

    424 Scopus citations

  • Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

    Lifelines Cohort Study, EchoGen consortium, AortaGen Consortium, CHARGE Consortium Heart Failure Working Group, KidneyGen Consortium & CKDGen consortium; Cardiogenics consortium; CardioGram, Oct 1 2011, In: Nature Genetics. 43, 10, p. 1005-1012 8 p.

    Research output: Contribution to journal › Article › peer-review

    350 Scopus citations

  • Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

    Saccone, N. L., Emery, L. S., Sofer, T., Gogarten, S. M., Becker, D. M., Bottinger, E. P., Chen, L. S., Culverhouse, R. C., Duan, W., Hancock, D. B., Hosgood, H. D., Johnson, E. O., Loos, R. J. F., Louie, T., Papanicolaou, G., Perreira, K. M., Rodriquez, E. J., Schurmann, C., Stilp, A. M., Szpiro, A. A., & 8 othersTalavera, G. A., Taylor, K. D., Thrasher, J. F., Yanek, L. R., Laurie, C. C., Pérez-Stable, E. J., Bierut, L. J. & Kaplan, R. C., Mar 6 2018, In: Nicotine and Tobacco Research. 20, 4, p. 448-457 10 p.

    Research output: Contribution to journal › Article › peer-review

    15 Scopus citations

  • Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN)

    Wojczynski, M. K., Parnell, L. D., Pollin, T. I., Lai, C. Q., Feitosa, M. F., O'Connell, J. R., Frazier-Wood, A. C., Gibson, Q., Aslibekyan, S., Ryan, K. A., Province, M. A., Tiwari, H. K., Ordovas, J. M., Shuldiner, A. R., Arnett, D. K. & Borecki, I. B., Oct 1 2015, In: Metabolism: clinical and experimental. 64, 10, p. 1359-1371 13 p.

    Research output: Contribution to journal › Article › peer-review

    28 Scopus citations

  • Genome-wide association study to identify common variants associated with brachial circumference: A meta-analysis of 14 cohorts

    Boraska, V., Day-Williams, A., Franklin, C. S., Elliott, K. S., Panoutsopoulou, K., Tachmazidou, I., Albrecht, E., Bandinelli, S., Beilin, L. J., Bochud, M., Cadby, G., Ernst, F., Evans, D. M., Hayward, C., Hicks, A. A., Huffman, J., Huth, C., James, A. L., Klopp, N., Kolcic, I., & 46 othersKutalik, Z., Lawlor, D. A., Musk, A. W., Pehlic, M., Pennell, C. E., Perry, J. R. B., Peters, A., Polasek, O., Pourcain, B. S., Ring, S. M., Salvi, E., Schipf, S., Staessen, J. A., Teumer, A., Timpson, N., Vitart, V., Warrington, N. M., Yaghootkar, H., Zemunik, T., Zgaga, L., An, P., Anttila, V., Borecki, I. B., Holmen, J., Ntalla, I., Palotie, A., Pietiläinen, K. H., Wedenoja, J., Winsvold, B. S., Dedoussis, G. V., Kaprio, J., Province, M. A., Zwart, J. A., Burnier, M., Campbell, H., Cusi, D., Davey Smith, G., Frayling, T. M., Gieger, C., Palmer, L. J., Pramstaller, P. P., Rudan, I., Völzke, H., Wichmann, H. E., Wright, A. F. & Zeggini, E., Mar 29 2012, In: PloS one. 7, 3, e31369.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations

  • Genome-wide characterization of endogenous retroviruses in the bat Myotis lucifugus reveals recent and diverse infections

    Zhuo, X., Rho, M. & Feschotte, C., 2013, In: Journal of virology. 87, 15, p. 8493-8501 9 p.

    Research output: Contribution to journal › Article › peer-review

    31 Scopus citations

  • Genome-wide discovery of loci influencing chemotherapy cytotoxicity

    Watters, J. W., Kraja, A., Meucci, M. A., Province, M. A. & McLeod, H. L., Aug 10 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 32, p. 11809-11814 6 p.

    Research output: Contribution to journal › Article › peer-review

    127 Scopus citations

  • Genome-wide DNA methylation profiling of primary colorectal laterally spreading tumors identifies disease-specific epimutations on common pathways

    Zhu, L., Yan, F., Wang, Z., Dong, H., Bian, C., Wang, T., Yu, E. & Li, J., Nov 15 2018, In: International Journal of Cancer. 143, 10, p. 2488-2498 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    18 Scopus citations

  • Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of Nitric oxide synthase and Fd59a/Fox-D

    Lacin, H., Rusch, J., Yeh, R. T., Fujioka, M., Wilson, B. A., Zhu, Y., Robie, A. A., Mistry, H., Wang, T., Jaynes, J. B. & Skeath, J. B., Apr 1 2014, In: Developmental Biology. 388, 1, p. 117-133 17 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    23 Scopus citations

  • Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

    Smith, C. E., Follis, J. L., Dashti, H. S., Tanaka, T., Graff, M., Fretts, A. M., Kilpeläinen, T. O., Wojczynski, M. K., Richardson, K., Nalls, M. A., Schulz, C. A., Liu, Y., Frazier-Wood, A. C., van Eekelen, E., Wang, C., de Vries, P. S., Mikkilä, V., Rohde, R., Psaty, B. M., Hansen, T., & 43 othersFeitosa, M. F., Lai, C. Q., Houston, D. K., Ferruci, L., Ericson, U., Wang, Z., de Mutsert, R., Oddy, W. H., de Jonge, E. A. L., Seppälä, I., Justice, A. E., Lemaitre, R. N., Sørensen, T. I. A., Province, M. A., Parnell, L. D., Garcia, M. E., Bandinelli, S., Orho-Melander, M., Rich, S. S., Rosendaal, F. R., Pennell, C. E., Kiefte-de Jong, J. C., Kähönen, M., Young, K. L., Pedersen, O., Aslibekyan, S., Rotter, J. I., Mook-Kanamori, D. O., Zillikens, M. C., Raitakari, O. T., North, K. E., Overvad, K., Arnett, D. K., Hofman, A., Lehtimäki, T., Tjønneland, A., Uitterlinden, A. G., Rivadeneira, F., Franco, O. H., German, J. B., Siscovick, D. S., Cupples, L. A. & Ordovás, J. M., Feb 1 2018, In: Molecular Nutrition and Food Research. 62, 3, 1700347.

    Research output: Contribution to journal › Article › peer-review

    6 Scopus citations

  • Genome-wide linkage analyses for age at diagnosis of hypertension and early-onset hypertension in the HyperGEN study

    Wilk, J. B., Djousse, L., Arnett, D. K., Hunt, S. C., Province, M. A., Heiss, G. & Myers, R. H., Sep 2004, In: American Journal of Hypertension. 17, 9, p. 839-844 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    33 Scopus citations

  • Genome-wide linkage analysis for loci affecting pulse pressure: The Family Blood Pressure Program

    Bielinski, S. J., Lynch, A. I., Miller, M. B., Weder, A., Cooper, R., Oberman, A., Chen, Y. D. I., Turner, S. T., Fornage, M., Province, M. & Arnett, D. K., Dec 2005, In: Hypertension. 46, 6, p. 1286-1293 8 p.

    Research output: Contribution to journal › Article › peer-review

    40 Scopus citations

  • Genome-wide linkage analysis of carotid artery traits in exceptionally long-lived families

    for the Long Life Family Study, Dec 2019, In: Atherosclerosis. 291, p. 19-26 8 p.

    Research output: Contribution to journal › Article › peer-review

    4 Scopus citations

  • Genome-wide linkage analysis of lipids in the hypertension genetic epidemiology network (HyperGEN) blood pressure study

    Coon, H., Leppert, M. F., Eckfeldt, J. H., Oberman, A., Myers, R. H., Peacock, J. M., Province, M. A., Hopkins, P. N. & Heiss, G., 2001, In: Arteriosclerosis, thrombosis, and vascular biology. 21, 12, p. 1969-1976 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    66 Scopus citations

  • Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease

    Silverman, E. K., Palmer, L. J., Mosley, J. D., Barth, M., Senter, J. M., Brown, A., Drazen, J. M., Kwiatkowski, D. J., Chapman, H. A., Campbell, E. J., Province, M. A., Rao, D. C., Reilly, J. J., Ginns, L. C., Speizer, F. E. & Weiss, S. T., 2002, In: American journal of human genetics. 70, 5, p. 1229-1239 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    160 Scopus citations

  • Genome-wide linkage analysis of severe, early-onset chronic obstructive pulmonary disease: Airflow obstruction and chronic bronchitis phenotypes

    Silverman, E. K., Mosley, J. D., Palmer, L. J., Barth, M., Senter, J. M., Brown, A., Drazen, J. M., Kwiatkowski, D. J., Chapman, H. A., Campbell, E. J., Province, M. A., Rao, D. C., Reilly, J. J., Ginns, L. C., Speizer, F. E. & Weiss, S. T., Mar 15 2002, In: Human molecular genetics. 11, 6, p. 623-632 10 p.

    Research output: Contribution to journal › Article › peer-review

    106 Scopus citations

  • Genome-wide linkage analysis of systolic and diastolic blood pressure: The Quebec family study

    Rice, T., Rankinen, T., Province, M. A., Chagnon, Y. C., Pérusse, L., Borecki, I. B., Bouchard, C. & Rao, D. C., Oct 17 2000, In: Circulation. 102, 16, p. 1956-1963 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    204 Scopus citations

  • Genome-wide linkage analysis replicates susceptibility locus for fasting plasma triglycerides: NHLBI Family Heart Study

    Arnett, D. K., Miller, M. B., Coon, H., Ellison, R. C., North, K. E., Province, M., Leppert, M. & Eckfeldt, J. H., 2004, In: Human genetics. 115, 6, p. 468-474 7 p.

    Research output: Contribution to journal › Article › peer-review

    12 Scopus citations

  • Genomewide linkage scan of resting blood pressure: Heritage family study

    Rice, T., Rankinen, T., Chagnon, Y. C., Province, M. A., Pérusse, L., Leon, A. S., Skinner, J. S., Wilmore, J. H., Bouchard, C. & Rao, D. C., 2002, In: Hypertension. 39, 6, p. 1037-1043 7 p.

    Research output: Contribution to journal › Article › peer-review

    86 Scopus citations

  • Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: Evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis

    An, P., Freedman, B. I., Hanis, C. L., Chen, Y. D. I., Weder, A. B., Schork, N. J., Boerwinkle, E., Province, M. A., Hsiung, C. A., Wu, X., Quertermous, T. & Rao, D. C., Mar 2005, In: Diabetes. 54, 3, p. 909-914 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    55 Scopus citations

  • Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists

    Johnson, A. D., Yanek, L. R., Chen, M. H., Faraday, N., Larson, M. G., Tofler, G., Lin, S. J., Kraja, A. T., Province, M. A., Yang, Q., Becker, D. M., O'Donnell, C. J. & Becker, L. C., Jul 2010, In: Nature Genetics. 42, 7, p. 608-613 6 p.

    Research output: Contribution to journal › Article › peer-review

    220 Scopus citations

  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Berndt, S. I., Gustafsson, S., Mägi, R., Ganna, A., Wheeler, E., Feitosa, M. F., Justice, A. E., Monda, K. L., Croteau-Chonka, D. C., Day, F. R., Esko, T., Fall, T., Ferreira, T., Gentilini, D., Jackson, A. U., Luan, J., Randall, J. C., Vedantam, S., Willer, C. J., Winkler, T. W., & 302 othersWood, A. R., Workalemahu, T., Hu, Y. J., Lee, S. H., Liang, L., Lin, D. Y., Min, J. L., Neale, B. M., Thorleifsson, G., Yang, J., Albrecht, E., Amin, N., Bragg-Gresham, J. L., Cadby, G., Heijer, M. D., Eklund, N., Fischer, K., Goel, A., Hottenga, J. J., Huffman, J. E., Jarick, I., Johansson, Å., Johnson, T., Kanoni, S., Kleber, M. E., König, I. R., Kristiansson, K., Kutalik, Z., Lamina, C., Lecoeur, C., Li, G., Mangino, M., McArdle, W. L., Medina-Gomez, C., Müller-Nurasyid, M., Ngwa, J. S., Nolte, I. M., Paternoster, L., Pechlivanis, S., Perola, M., Peters, M. J., Preuss, M., Rose, L. M., Shi, J., Shungin, D., Smith, A. V., Strawbridge, R. J., Surakka, I., Teumer, A., Trip, M. D., Tyrer, J., Van Vliet-Ostaptchouk, J. V., Vandenput, L., Waite, L. L., Zhao, J. H., Absher, D., Asselbergs, F. W., Atalay, M., Attwood, A. P., Balmforth, A. J., Basart, H., Beilby, J., Bonnycastle, L. L., Brambilla, P., Bruinenberg, M., Campbell, H., Chasman, D. I., Chines, P. S., Collins, F. S., Connell, J. M., O Cookson, W., De Faire, U., De Vegt, F., Dei, M., Dimitriou, M., Edkins, S., Estrada, K., Evans, D. M., Farrall, M., Ferrario, M. M., Ferrières, J., Franke, L., Frau, F., Gejman, P. V., Grallert, H., Grönberg, H., Gudnason, V., Hall, A. S., Hall, P., Hartikainen, A. L., Hayward, C., Heard-Costa, N. L., Heath, A. C., Hebebrand, J., Homuth, G., Hu, F. B., Hunt, S. E., Hyppönen, E., Iribarren, C., Jacobs, K. B., Jansson, J. O., Jula, A., Kähönen, M., Kathiresan, S., Kee, F., Khaw, K. T., Kivimäki, M., Koenig, W., Kraja, A. T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Laitinen, J. H., Lakka, T. A., Langenberg, C., Launer, L. J., Lind, L., Lindström, J., Liu, J., Liuzzi, A., Lokki, M. L., Lorentzon, M., Madden, P. A., Magnusson, P. K., Manunta, P., Marek, D., März, W., Leach, I. M., McKnight, B., Medland, S. E., Mihailov, E., Milani, L., Montgomery, G. W., Mooser, V., Mühleisen, T. W., Munroe, P. B., Musk, A. W., Narisu, N., Navis, G., Nicholson, G., Nohr, E. A., Ong, K. K., Oostra, B. A., Palmer, C. N., Palotie, A., Peden, J. F., Pedersen, N., Peters, A., Polasek, O., Pouta, A., Pramstaller, P. P., Prokopenko, I., Pütter, C., Radhakrishnan, A., Raitakari, O., Rendon, A., Rivadeneira, F., Rudan, I., Saaristo, T. E., Sambrook, J. G., Sanders, A. R., Sanna, S., Saramies, J., Schipf, S., Schreiber, S., Schunkert, H., Shin, S. Y., Signorini, S., Sinisalo, J., Skrobek, B., Soranzo, N., Stancáková, A., Stark, K., Stephens, J. C., Stirrups, K., Stolk, R. P., Stumvoll, M., Swift, A. J., Theodoraki, E. V., Thorand, B., Tregouet, D. A., Tremoli, E., Van Der Klauw, M. M., Van Meurs, J. B., Vermeulen, S. H., Viikari, J., Virtamo, J., Vitart, V., Waeber, G., Wang, Z., Widén, E., Wild, S. H., Willemsen, G., Winkelmann, B. R., Witteman, J. C., Wolffenbuttel, B. H., Wong, A., Wright, A. F., Zillikens, M. C., Amouyel, P., Boehm, B. O., Boerwinkle, E., Boomsma, D. I., Caulfield, M. J., Chanock, S. J., Cupples, L. A., Cusi, D., Dedoussis, G. V., Erdmann, J., Eriksson, J. G., Franks, P. W., Froguel, P., Gieger, C., Gyllensten, U., Hamsten, A., Harris, T. B., Hengstenberg, C., Hicks, A. A., Hingorani, A., Hinney, A., Hofman, A., Hovingh, K. G., Hveem, K., Illig, T., Jarvelin, M. R., Jöckel, K. H., Keinanen-Kiukaanniemi, S. M., Kiemeney, L. A., Kuh, D., Laakso, M., Lehtimäki, T., Levinson, D. F., Martin, N. G., Metspalu, A., Morris, A. D., Nieminen, M. S., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Ouwehand, W. H., Palmer, L. J., Penninx, B., Power, C., Province, M. A., Psaty, B. M., Qi, L., Rauramaa, R., Ridker, P. M., Ripatti, S., Salomaa, V., Samani, N. J., Snieder, H., Sørensen, T. I., Spector, T. D., Stefansson, K., Tönjes, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Van Der Harst, P., Vollenweider, P., Wallaschofski, H., Wareham, N. J., Watkins, H., Wichmann, H. E., Wilson, J. F., Abecasis, G. R., Assimes, T. L., Barroso, I., Boehnke, M., Borecki, I. B., Deloukas, P., Fox, C. S., Frayling, T., Groop, L. C., Haritunian, T., Heid, I. M., Hunter, D., Kaplan, R. C., Karpe, F., Moffatt, M. F., Mohlke, K. L., O'Connell, J. R., Pawitan, Y., Schadt, E. E., Schlessinger, D., Steinthorsdottir, V., Strachan, D. P., Thorsteinsdottir, U., Van Duijn, C. M., Visscher, P. M., Di Blasio, A. M., Hirschhorn, J. N., Lindgren, C. M., Morris, A. P., Meyre, D., Scherag, A., McCarthy, M. I., Speliotes, E. K., North, K. E., Loos, R. J. & Ingelsson, E., May 2013, In: Nature Genetics. 45, 5, p. 501-512 12 p.

    Research output: Contribution to journal › Article › peer-review

    457 Scopus citations

  • Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

    Merino, J., Dashti, H. S., Li, S. X., Sarnowski, C., Justice, A. E., Graff, M., Papoutsakis, C., Smith, C. E., Dedoussis, G. V., Lemaitre, R. N., Wojczynski, M. K., Männistö, S., Ngwa, J. S., Kho, M., Ahluwalia, T. S., Pervjakova, N., Houston, D. K., Bouchard, C., Huang, T., Orho-Melander, M., & 86 othersFrazier-Wood, A. C., Mook-Kanamori, D. O., Pérusse, L., Pennell, C. E., de Vries, P. S., Voortman, T., Li, O., Kanoni, S., Rose, L. M., Lehtimäki, T., Zhao, J. H., Feitosa, M. F., Luan, J., McKeown, N. M., Smith, J. A., Hansen, T., Eklund, N., Nalls, M. A., Rankinen, T., Huang, J., Hernandez, D. G., Schulz, C. A., Manichaikul, A., Li-Gao, R., Vohl, M. C., Wang, C. A., van Rooij, F. J. A., Shin, J., Kalafati, I. P., Day, F., Ridker, P. M., Kähönen, M., Siscovick, D. S., Langenberg, C., Zhao, W., Astrup, A., Knekt, P., Garcia, M., Rao, D. C., Qi, Q., Ferrucci, L., Ericson, U., Blangero, J., Hofman, A., Pausova, Z., Mikkilä, V., Wareham, N. J., Kardia, S. L. R., Pedersen, O., Jula, A., Curran, J. E., Zillikens, M. C., Viikari, J. S., Forouhi, N. G., Ordovás, J. M., Lieske, J. C., Rissanen, H., Uitterlinden, A. G., Raitakari, O. T., Kiefte-de Jong, J. C., Dupuis, J., Rotter, J. I., North, K. E., Scott, R. A., Province, M. A., Perola, M., Cupples, L. A., Turner, S. T., Sørensen, T. I. A., Salomaa, V., Liu, Y., Sung, Y. J., Qi, L., Bandinelli, S., Rich, S. S., de Mutsert, R., Tremblay, A., Oddy, W. H., Franco, O. H., Paus, T., Florez, J. C., Deloukas, P., Lyytikäinen, L. P., Chasman, D. I., Chu, A. Y. & Tanaka, T., Dec 1 2019, In: Molecular Psychiatry. 24, 12, p. 1920-1932 13 p.

    Research output: Contribution to journal › Article › peer-review

    39 Scopus citations

  • Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women

    Jones, G., Trajanoska, K., Santanasto, A. J., Stringa, N., Kuo, C. L., Atkins, J. L., Lewis, J. R., Duong, T. V., Hong, S., Biggs, M. L., Luan, J., Sarnowski, C., Lunetta, K. L., Tanaka, T., Wojczynski, M. K., Cvejkus, R., Nethander, M., Ghasemi, S., Yang, J., Zillikens, M. C., & 46 othersWalter, S., Sicinski, K., Kague, E., Ackert-Bicknell, C. L., Arking, D. E., Windham, B. G., Boerwinkle, E., Grove, M. L., Graff, M., Spira, D., Demuth, I., van der Velde, N., de Groot, L. C. P. G. M., Psaty, B. M., Odden, M. C., Fohner, A. E., Langenberg, C., Wareham, N. J., Bandinelli, S., van Schoor, N. M., Huisman, M., Tan, Q., Zmuda, J., Mellström, D., Karlsson, M., Bennett, D. A., Buchman, A. S., De Jager, P. L., Uitterlinden, A. G., Völker, U., Kocher, T., Teumer, A., Rodriguéz-Mañas, L., García, F. J., Carnicero, J. A., Herd, P., Bertram, L., Ohlsson, C., Murabito, J. M., Melzer, D., Kuchel, G. A., Ferrucci, L., Karasik, D., Rivadeneira, F., Kiel, D. P. & Pilling, L. C., Dec 1 2021, In: Nature communications. 12, 1, 654.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    49 Scopus citations

  • Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake

    Tanaka, T., Ngwa, J. S., Van Rooij, F. J. A., Zillikens, M. C., Wojczynski, M. K., Frazier-Wood, A. C., Houston, D. K., Kanoni, S., Lemaitre, R. N., Luan, J. N. A., Mikkilä, V., Renstrom, F., Sonestedt, E., Zhao, J. H., Chu, A. Y., Qi, L., Chasman, D. I., De Oliveira Otto, M. C., Dhurandhar, E. J., Feitosa, M. F., & 46 othersJohansson, I., Khaw, K. T., Lohman, K. K., Manichaikul, A., McKeown, N. M., Mozaffarian, D., Singleton, A., Stirrups, K., Viikari, J., Ye, Z., Bandinelli, S., Barroso, I., Deloukas, P., Forouhi, N. G., Hofman, A., Liu, Y., Lyytikäinen, L. P., North, K. E., Dimitriou, M., Hallmans, G., Kähönen, M., Langenberg, C., Ordovas, J. M., Uitterlinden, A. G., Hu, F. B., Kalafati, I. P., Raitakari, O., Franco, O. H., Johnson, A., Emilsson, V., Schrack, J. A., Semba, R. D., Siscovick, D. S., Arnett, D. K., Borecki, I. B., Franks, P. W., Kritchevsky, S. B., Loos, T. L. R. J. F., Orho-Melander, M., Rotter, J. I., Wareham, N. J., Witteman, J. C. M., Ferrucci, L., Dedoussis, G., Cupples, L. A. & Nettleton, J. A., Jun 1 2013, In: American Journal of Clinical Nutrition. 97, 6, p. 1395-1402 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    176 Scopus citations

  • Genome-wide meta-analysis points to CTC1 and ZNf676 as genes regulating telomere homeostasis in humans

    Mangino, M., Hwang, S. J., Spector, T. D., Hunt, S. C., Kimura, M., Fitzpatrick, A. L., Christiansen, L., Petersen, I., Elbers, C. C., Harris, T., Chen, W., Srinivasan, S. R., Kark, J. D., Benetos, A., El shamieh, S., Visvikis-Siest, S., Christensen, K., Berenson, G. S., Valdes, A. M., Vinuela, A., & 19 othersGarcia, M., Arnett, D. K., Broeckel, U., Province, M. A., Pankow, J. S., Kammerer, C., Liu, Y., Nalls, M., Tishkoff, S., Thomas, F., Ziv, E., Psaty, B. M., Bis, J. C., Rotter, J. I., Taylor, K. D., Smith, E., Schork, N. J., Levy, D. & Aviv, A., Dec 2012, In: Human molecular genetics. 21, 24, p. 5385-5394 10 p., dds382.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    179 Scopus citations

  • Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence

    Hancock, D. B., Reginsson, G. W., Gaddis, N. C., Chen, X., Saccone, N. L., Lutz, S. M., Qaiser, B., Sherva, R., Steinberg, S., Zink, F., Stacey, S. N., Glasheen, C., Chen, J., Gu, F., Frederiksen, B. N., Loukola, A., Gudbjartsson, D. F., Brüske, I., Landi, M. T., Bickeböller, H., & 14 othersMadden, P., Farrer, L., Kaprio, J., Kranzler, H. R., Gelernter, J., Baker, T. B., Kraft, P., Amos, C. I., Caporaso, N. E., Hokanson, J. E., Bierut, L. J., Thorgeirsson, T. E., Johnson, E. O. & Stefansson, K., Oct 6 2015, In: Translational psychiatry. 5, e651.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    68 Scopus citations

  • Genome-wide scans for heritability of fasting serum insulin and glucose concentrations in hypertensive families

    Freedman, B. I., Rich, S. S., Sale, M. M., Heiss, G., Djoussé, L., Pankow, J. S., Province, M. A., Rao, D. C., Lewis, C. E., Chen, Y. D. I. & Beck, S. R., Apr 2005, In: Diabetologia. 48, 4, p. 661-668 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    19 Scopus citations

  • Genome wide screens in yeast to identify potential binding sites and target genes of DNA-binding proteins

    Zeng, J., Yan, J., Wang, T., Mosbrook-Davis, D., Dolan, K. T., Christensen, R., Stormo, G. D., Haussler, D., Lathrop, R. H., Brachmann, R. K. & Burgess, S. M., Jan 2008, In: Nucleic acids research. 36, 1, e8.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    20 Scopus citations

  • Genome-wide search for genes related to the fat-free body mass in the quebec family study

    Chagnon, Y. C., Borecki, I. B., Pérusse, L., Roy, S., Lacaille, M., Chagnon, M., Ho-Kim, M. A., Rice, T., Province, M. A., Rao, D. C. & Bouchard, C., 2000, In: Metabolism: clinical and experimental. 49, 2, p. 203-207 5 p.

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    104 Scopus citations

  • Genomic environments scale the activities of diverse core promoters

    Hong, C. K. Y. & Cohen, B. A., Jan 1 2022, In: Genome research. 32, 1, p. 85-96 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    14 Scopus citations

  • Genomic footprints of activated telomere maintenance mechanisms in cancer

    PCAWG Consortium & PCAWG-Structural Variation Working Group, Dec 1 2020, In: Nature communications. 11, 1, 733.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    65 Scopus citations

  • Genomic Patterns of De Novo Mutation in Simplex Autism

    Turner, T. N., Coe, B. P., Dickel, D. E., Hoekzema, K., Nelson, B. J., Zody, M. C., Kronenberg, Z. N., Hormozdiari, F., Raja, A., Pennacchio, L. A., Darnell, R. B. & Eichler, E. E., Oct 19 2017, In: Cell. 171, 3, p. 710-722.e12

    Research output: Contribution to journal › Article › peer-review

    Open Access
    214 Scopus citations

  • Genomic scan for maximal oxygen uptake and its response to training in the HERITAGE family study

    Bouchard, C., Rankinen, T., Chagnon, Y. C., Rice, T., Pérusse, L., Gagnon, J., Borecki, I., An, P., Leon, A. S., Skinner, J. S., Wilmore, J. H., Province, M. & Rao, D. C., Feb 2000, In: Journal of Applied Physiology. 88, 2, p. 551-559 9 p.

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  • Genomics of human congenital hydrocephalus

    Kundishora, A. J., Singh, A. K., Allington, G., Duy, P. Q., Ryou, J., Alper, S. L., Jin, S. C. & Kahle, K. T., Nov 2021, In: Child's Nervous System. 37, 11, p. 3325-3340 16 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations

  • Genomics Research with Undiagnosed Children: Ethical Challenges at the Boundaries of Research and Clinical Care

    Undiagnosed Diseases Network, Oct 2023, In: Journal of Pediatrics. 261, 113537.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • Genotype-by-sex interaction on fasting insulin concentration: The HyperGEN study

    North, K. E., Franceschini, N., Borecki, I. B., Gu, C. C., Heiss, G., Province, M. A., Arnett, D. K., Lewis, C. E., Miller, M. B., Myers, R. H., Hunt, S. C. & Freedman, B. I., Jan 2007, In: Diabetes. 56, 1, p. 137-142 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • Germline mosaicism of a missense variant in KCNC2 in a multiplex family with autism and epilepsy characterized by long-read sequencing

    Mehinovic, E., Gray, T., Campbell, M., Ekholm, J., Wenger, A., Rowell, W., Grudo, A., Grimwood, J., Korlach, J., Gurnett, C., Constantino, J. N. & Turner, T. N., Jul 2022, In: American Journal of Medical Genetics, Part A. 188, 7, p. 2071-2081 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    3 Scopus citations

  • Germline stem cell differentiation entails regional control of cell fate regulator GLD-1 in Caenorhabditis elegans

    Brenner, J. L. & Schedl, T., Mar 2016, In: Genetics. 202, 3, p. 1085-1103 19 p.

    Research output: Contribution to journal › Article › peer-review

    33 Scopus citations

  • Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors

    Berry, L. W., Westlund, B. & Schedl, T., Feb 1997, In: Development. 124, 4, p. 925-936 12 p.

    Research output: Contribution to journal › Article › peer-review

    218 Scopus citations

  • GermOnline, a cross-species community knowledgebase on germ cell differentiation

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    Research output: Contribution to journal › Article › peer-review

    24 Scopus citations

  • GFRα1-deficient mice have deficits in the enteric nervous system and kidneys

    Enomoto, H., Araki, T., Jackman, A., Heuckeroth, R. O., Snider, W. D., Johnson, E. M. & Milbrandt, J., Aug 1998, In: Neuron. 21, 2, p. 317-324 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    410 Scopus citations

  • GFRα1 expression in cells lacking ret is dispensable for organogenesis and nerve regeneration

    Enomoto, H., Hughes, I., Golden, J., Baloh, R. H., Yonemura, S., Heuckeroth, R. O., Johnson, E. M. & Milbrandt, J., Nov 18 2004, In: Neuron. 44, 4, p. 623-636 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    61 Scopus citations

  • GFRα3 is an orphan member of the GDNF/neurturin/persephin receptor family

    Baloh, R. H., Gorodinsky, A., Golden, J. P., Tansey, M. G., Keck, C. L., Popescu, N. C., Johnson, E. M. & Milbrandt, J., May 12 1998, In: Proceedings of the National Academy of Sciences of the United States of America. 95, 10, p. 5801-5806 6 p.

    Research output: Contribution to journal › Article › peer-review

    116 Scopus citations

  • GFRα-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival

    Tansey, M. G., Baloh, R. H., Milbrandt, J. & Johnson, E. M., 2000, In: Neuron. 25, 3, p. 611-623 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    262 Scopus citations