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  • 2012

    Comparative epigenomic annotation of regulatory DNA

    Xiao, S., Xie, D., Cao, X., Yu, P., Xing, X., Chen, C. C., Musselman, M., Xie, M., West, F. D., Lewin, H. A., Wang, T. & Zhong, S., Jun 8 2012, In: Cell. 149, 6, p. 1381-1392 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    140 Scopus citations
  • Complex effects of nucleotide variants in a mammalian cis-regulatory element

    Kwasnieski, J. C., Mogno, I., Myers, C. A., Corbo, J. C. & Cohen, B. A., Nov 20 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 47, p. 19498-19503 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    154 Scopus citations
  • Conserved motifs and prediction of regulatory modules in caenorhabditis elegans

    Zhao, G., Ihuegbu, N., Lee, M., Schriefer, L., Wang, T. & Stormo, G. D., Apr 2012, In: G3: Genes, Genomes, Genetics. 2, 4, p. 469-481 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    14 Scopus citations
  • Creation and preliminary characterization of a leptin knockout rat

    Vaira, S., Yang, C., McCoy, A., Keys, K., Xue, S., Weinstein, E. J., Novack, D. V. & Cui, X., Nov 1 2012, In: Endocrinology. 153, 11, p. 5622-5628 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    29 Scopus citations
  • Cyclin-Dependent Kinases Are Regulators and Effectors of Oscillations Driven by a Transcription Factor Network

    Simmons Kovacs, L. A., Mayhew, M. B., Orlando, D. A., Jin, Y., Li, Q., Huang, C., Reed, S. I., Mukherjee, S. & Haase, S. B., Mar 9 2012, In: Molecular cell. 45, 5, p. 669-679 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    49 Scopus citations
  • Detection of rare genomic variants from pooled sequencing using SPLINTER

    Vallania, F., Ramos, E., Cresci, S., Mitra, R. D. & Druley, T. E., Jun 23 2012, In: Journal of Visualized Experiments. 64, p. 1-9 9 p., e3943.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Developmental Plasticity Is Bound by Pluripotency and the Fgf and Wnt Signaling Pathways

    Morris, S. A., Guo, Y. & Zernicka-Goetz, M., Oct 25 2012, In: Cell Reports. 2, 4, p. 756-765 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    69 Scopus citations
  • Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems

    Patel, A., Harker, N., Moreira-Santos, L., Ferreira, M., Alden, K., Timmis, J., Foster, K., Garefalaki, A., Pachnis, P., Andrews, P., Enomoto, H., Milbrandt, J., Pachnis, V., Coles, M. C., Kioussis, D. & Veiga-Fernandes, H., Jul 31 2012, In: Science signaling. 5, 235, ra55.

    Research output: Contribution to journalArticlepeer-review

    51 Scopus citations
  • Dissection of the phenotypic and genotypic associations with nicotinic dependence

    Chen, L. S., Baker, T. B., Grucza, R., Wang, J. C., Johnson, E. O., Breslau, N., Hatsukami, D., Smith, S. S., Saccone, N., Saccone, S., Rice, J. P., Goate, A. M. & Bierut, L. J., Nov 2012, In: Nicotine and Tobacco Research. 14, 4, p. 425-433 9 p.

    Research output: Contribution to journalArticlepeer-review

    39 Scopus citations
  • Dual Leucine Zipper Kinase Is Required for Retrograde Injury Signaling and Axonal Regeneration

    Shin, J. E., Cho, Y., Beirowski, B., Milbrandt, J., Cavalli, V. & DiAntonio, A., Jun 21 2012, In: Neuron. 74, 6, p. 1015-1022 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    214 Scopus citations
  • Dynamics of anterior-posterior axis formation in the developing mouse embryo

    Morris, S. A., Grewal, S., Barrios, F., Patankar, S. N., Strauss, B., Buttery, L., Alexander, M., Shakesheff, K. M. & Zernicka-Goetz, M., 2012, In: Nature communications. 3, 673.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    63 Scopus citations
  • Exploring the DNA-recognition potential of homeodomains

    Chu, S. W., Noyes, M. B., Christensen, R. G., Pierce, B. G., Zhu, L. J., Weng, Z., Stormo, G. D. & Wolfe, S. A., Oct 2012, In: Genome research. 22, 10, p. 1889-1898 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    18 Scopus citations
  • Fast, sensitive discovery of conserved genome-wide motifs

    Ihuegbu, N. E., Stormo, G. D. & Buhler, J., Feb 1 2012, In: Journal of Computational Biology. 19, 2, p. 139-147 9 p.

    Research output: Contribution to journalArticlepeer-review

    6 Scopus citations
  • FTO genotype is associated with phenotypic variability of body mass index

    Yang, J., Loos, R. J. F., Powell, J. E., Medland, S. E., Speliotes, E. K., Chasman, D. I., Rose, L. M., Thorleifsson, G., Steinthorsdottir, V., Mägi, R., Waite, L., Vernon Smith, A., Yerges-Armstrong, L. M., Monda, K. L., Hadley, D., Mahajan, A., Li, G., Kapur, K., Vitart, V., Huffman, J. E., & 152 othersWang, S. R., Palmer, C., Esko, T., Fischer, K., Hua Zhao, J., Demirkan, A., Isaacs, A., Feitosa, M. F., Luan, JA., Heard-Costa, N. L., White, C., Jackson, A. U., Preuss, M., Ziegler, A., Eriksson, J., Kutalik, Z., Frau, F., Nolte, I. M., Van Vliet-Ostaptchouk, J. V., Hottenga, J. J., Jacobs, K. B., Verweij, N., Goel, A., Medina-Gomez, C., Estrada, K., Bragg-Gresham, J. L., Sanna, S., Sidore, C., Tyrer, J., Teumer, A., Prokopenko, I., Mangino, M., Lindgren, C. M., Assimes, T. L., Shuldiner, A. R., Hui, J., Beilby, J. P., McArdle, W. L., Hall, P., Haritunians, T., Zgaga, L., Kolcic, I., Polasek, O., Zemunik, T., Oostra, B. A., Juhani Junttila, M., Grönberg, H., Schreiber, S., Peters, A., Hicks, A. A., Stephens, J., Foad, N. S., Laitinen, J., Pouta, A., Kaakinen, M., Willemsen, G., Vink, J. M., Wild, S. H., Navis, G., Asselbergs, F. W., Homuth, G., John, U., Iribarren, C., Harris, T., Launer, L., Gudnason, V., O'Connell, J. R., Boerwinkle, E., Cadby, G., Palmer, L. J., James, A. L., Musk, A. W., Ingelsson, E., Psaty, B. M., Beckmann, J. S., Waeber, G., Vollenweider, P., Hayward, C., Wright, A. F., Rudan, I., Groop, L. C., Metspalu, A., Tee Khaw, K., Van Duijn, C. M., Borecki, I. B., Province, M. A., Wareham, N. J., Tardif, J. C., Huikuri, H. V., Adrienne Cupples, L., Atwood, L. D., Fox, C. S., Boehnke, M., Collins, F. S., Mohlke, K. L., Erdmann, J., Schunkert, H., Hengstenberg, C., Stark, K., Lorentzon, M., Ohlsson, C., Cusi, D., Staessen, J. A., Van Der Klauw, M. M., Pramstaller, P. P., Kathiresan, S., Jolley, J. D., Ripatti, S., Jarvelin, M. R., De Geus, E. J. C., Boomsma, D. I., Penninx, B., Wilson, J. F., Campbell, H., Chanock, S. J., Van Der Harst, P., Hamsten, A., Watkins, H., Hofman, A., Witteman, J. C., Carola Zillikens, M., Uitterlinden, A. G., Rivadeneira, F., Carola Zillikens, M., Kiemeney, L. A., Vermeulen, S. H., Abecasis, G. R., Schlessinger, D., Schipf, S., Stumvoll, M., Tönjes, A., Spector, T. D., North, K. E., Lettre, G., McCarthy, M. I., Berndt, S. I., Heath, A. C., Madden, P. A. F., Nyholt, D. R., Montgomery, G. W., Martin, N. G., McKnight, B., Strachan, D. P., Hill, W. G., Snieder, H., Ridker, P. M., Thorsteinsdottir, U., Stefansson, K., Frayling, T. M., Hirschhorn, J. N., Goddard, M. E. & Visscher, P. M., Oct 11 2012, In: Nature. 490, 7419, p. 267-273 7 p.

    Research output: Contribution to journalArticlepeer-review

    292 Scopus citations
  • Gene-Centric Meta-Analysis of Lipid Traits in African, East Asian and Hispanic Populations

    Elbers, C. C., Guo, Y., Tragante, V., van Iperen, E. P. A., Lanktree, M. B., Castillo, B. A., Chen, F., Yanek, L. R., Wojczynski, M. K., Li, Y. R., Ferwerda, B., Ballantyne, C. M., Buxbaum, S. G., Chen, Y. D. I., Chen, W. M., Cupples, L. A., Cushman, M., Duan, Y., Duggan, D., Evans, M. K., & 50 othersFernandes, J. K., Fornage, M., Garcia, M., Garvey, W. T., Glazer, N., Gomez, F., Harris, T. B., Halder, I., Howard, V. J., Keller, M. F., Kamboh, M. I., Kooperberg, C., Kritchevsky, S. B., LaCroix, A., Liu, K., Liu, Y., Musunuru, K., Newman, A. B., Onland-Moret, N. C., Ordovas, J., Peter, I., Post, W., Redline, S., Reis, S. E., Saxena, R., Schreiner, P. J., Volcik, K. A., Wang, X., Yusuf, S., Zonderland, A. B., Anand, S. S., Becker, D. M., Psaty, B., Rader, D. J., Reiner, A. P., Rich, S. S., Rotter, J. I., Sale, M. M., Tsai, M. Y., Borecki, I. B., Hegele, R. A., Kathiresan, S., Nalls, M. A., Taylor, H. A., Hakonarson, H., Sivapalaratnam, S., Asselbergs, F. W., Drenos, F., Wilson, J. G. & Keating, B. J., Dec 7 2012, In: PloS one. 7, 12, e50198.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    35 Scopus citations
  • Genome-wide association and functional follow-up reveals new loci for kidney function

    Pattaro, C., Köttgen, A., Teumer, A., Garnaas, M., Böger, C. A., Fuchsberger, C., Olden, M., Chen, M. H., Tin, A., Taliun, D., Li, M., Gao, X., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C., O'Seaghdha, C. M., Glazer, N., Isaacs, A., Liu, C. T., & 146 othersSmith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Johnson, A. D., Gierman, H. J., Feitosa, M., Hwang, S. J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, Å., Tönjes, A., Dehghan, A., Chouraki, V., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimäki, T., Esko, T., Deshmukh, H., Ulivi, S., Chu, A. Y., Murgia, F., Trompet, S., Imboden, M., Kollerits, B., Pistis, G., Harris, T. B., Launer, L. J., Aspelund, T., Eiriksdottir, G., Mitchell, B. D., Boerwinkle, E., Schmidt, H., Cavalieri, M., Rao, M., Hu, F. B., Demirkan, A., Oostra, B. A., de Andrade, M., Turner, S. T., Ding, J., Andrews, J. S., Freedman, B. I., Koenig, W., Illig, T., Döring, A., Wichmann, H. E., Kolcic, I., Zemunik, T., Boban, M., Minelli, C., Wheeler, H. E., Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Nöthlings, U., Jacobs, G., Biffar, R., Endlich, K., Ernst, F., Homuth, G., Kroemer, H. K., Nauck, M., Stracke, S., Völker, U., Völzke, H., Kovacs, P., Stumvoll, M., Mägi, R., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Aulchenko, Y. S., Polasek, O., Hastie, N., Vitart, V., Helmer, C., Wang, J. J., Ruggiero, D., Bergmann, S., Kähönen, M., Viikari, J., Nikopensius, T., Province, M., Ketkar, S., Colhoun, H., Doney, A., Robino, A., Giulianini, F., Krämer, B. K., Portas, L., Ford, I., Buckley, B. M., Adam, M., Thun, G. A., Paulweber, B., Haun, M., Sala, C., Metzger, M., Mitchell, P., Ciullo, M., Kim, S. K., Vollenweider, P., Raitakari, O., Metspalu, A., Palmer, C., Gasparini, P., Pirastu, M., Jukema, J. W., Probst-Hensch, N. M., Kronenberg, F., Toniolo, D., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Ferrucci, L., Siscovick, D. S., van Duijn, C. M., Borecki, I., Kardia, S. L. R., Liu, Y., Curhan, G. C., Rudan, I., Gyllensten, U., Wilson, J. F., Franke, A., Pramstaller, P. P., Rettig, R., Prokopenko, I., Witteman, J. C. M., Hayward, C., Ridker, P., Parsa, A., Bochud, M., Heid, I. M., Goessling, W., Chasman, D. I., Kao, W. H. L. & Fox, C. S., Mar 2012, In: PLoS genetics. 8, 3, e1002584.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    144 Scopus citations
  • Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

    Wilk, J. B., Shrine, N. R. G., Loehr, L. R., Zhao, J. H., Manichaikul, A., Lopez, L. M., Smith, A. V., Heckbert, S. R., Smolonska, J., Tang, W., Loth, D. W., Curjuric, I., Hui, J., Cho, M. H., Latourelle, J. C., Henry, A. P., Aldrich, M., Bakke, P., Beaty, T. H., Bentley, A. R., & 59 othersBorecki, I. B., Brusselle, G. G., Burkart, K. M., Chen, T. H., Couper, D., Crapo, J. D., Davies, G., Dupuis, J., Franceschini, N., Gulsvik, A., Hancock, D. B., Harris, T. B., Hofman, A., Imboden, M., James, A. L., Khaw, K. T., Lahousse, L., Launer, L. J., Litonjua, A., Liu, Y., Lohman, K. K., Lomas, D. A., Lumley, T., Marciante, K. D., McArdle, W. L., Meibohm, B., Morrison, A. C., Musk, A. W., Myers, R. H., North, K. E., Postma, D. S., Psaty, B. M., Rich, S. S., Rivadeneira, F., Rochat, T., Rotter, J. I., Soler Artigas, M., Starr, J. M., Uitterlinden, A. G., Wareham, N. J., Wijmenga, C., Zanen, P., Province, M. A., Silverman, E. K., Deary, I. J., Palmer, L. J., Cassano, P. A., Gudnason, V., Barr, R. G., Loos, R. J. F., Strachan, D. P., London, S. J., Boezen, H. M., Probst-Hensch, N., Gharib, S. A., Hall, I. P., O'Connor, G. T., Tobin, M. D. & Stricker, B. H., Oct 1 2012, In: American journal of respiratory and critical care medicine. 186, 7, p. 622-632 11 p.

    Research output: Contribution to journalArticlepeer-review

    144 Scopus citations
  • Genome-wide association study to identify common variants associated with brachial circumference: A meta-analysis of 14 cohorts

    Boraska, V., Day-Williams, A., Franklin, C. S., Elliott, K. S., Panoutsopoulou, K., Tachmazidou, I., Albrecht, E., Bandinelli, S., Beilin, L. J., Bochud, M., Cadby, G., Ernst, F., Evans, D. M., Hayward, C., Hicks, A. A., Huffman, J., Huth, C., James, A. L., Klopp, N., Kolcic, I., & 46 othersKutalik, Z., Lawlor, D. A., Musk, A. W., Pehlic, M., Pennell, C. E., Perry, J. R. B., Peters, A., Polasek, O., Pourcain, B. S., Ring, S. M., Salvi, E., Schipf, S., Staessen, J. A., Teumer, A., Timpson, N., Vitart, V., Warrington, N. M., Yaghootkar, H., Zemunik, T., Zgaga, L., An, P., Anttila, V., Borecki, I. B., Holmen, J., Ntalla, I., Palotie, A., Pietiläinen, K. H., Wedenoja, J., Winsvold, B. S., Dedoussis, G. V., Kaprio, J., Province, M. A., Zwart, J. A., Burnier, M., Campbell, H., Cusi, D., Davey Smith, G., Frayling, T. M., Gieger, C., Palmer, L. J., Pramstaller, P. P., Rudan, I., Völzke, H., Wichmann, H. E., Wright, A. F. & Zeggini, E., Mar 29 2012, In: PloS one. 7, 3, e31369.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Genome-wide meta-analysis points to CTC1 and ZNf676 as genes regulating telomere homeostasis in humans

    Mangino, M., Hwang, S. J., Spector, T. D., Hunt, S. C., Kimura, M., Fitzpatrick, A. L., Christiansen, L., Petersen, I., Elbers, C. C., Harris, T., Chen, W., Srinivasan, S. R., Kark, J. D., Benetos, A., El shamieh, S., Visvikis-Siest, S., Christensen, K., Berenson, G. S., Valdes, A. M., Vinuela, A., & 19 othersGarcia, M., Arnett, D. K., Broeckel, U., Province, M. A., Pankow, J. S., Kammerer, C., Liu, Y., Nalls, M., Tishkoff, S., Thomas, F., Ziv, E., Psaty, B. M., Bis, J. C., Rotter, J. I., Taylor, K. D., Smith, E., Schork, N. J., Levy, D. & Aviv, A., Dec 2012, In: Human molecular genetics. 21, 24, p. 5385-5394 10 p., dds382.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    161 Scopus citations
  • Global gene deletion analysis exploring yeast filamentous growth

    Ryan, O., Shapiro, R. S., Kurat, C. F., Mayhew, D., Baryshnikova, A., Chin, B., Lin, Z. Y., Cox, M. J., Vizeacoumar, F., Cheung, D., Bahr, S., Tsui, K., Tebbji, F., Sellam, A., Istel, F., Schwarzmüller, T., Reynolds, T. B., Kuchler, K., Gifford, D. K., Whiteway, M., & 9 othersGiaever, G., Nislow, C., Costanzo, M., Gingras, A. C., Mitra, R. D., Andrews, B., Fink, G. R., Cowen, L. E. & Boone, C., Sep 14 2012, In: Science. 337, 6100, p. 1352-1356 5 p.

    Research output: Contribution to journalArticlepeer-review

    145 Scopus citations
  • Healing quantitative trait loci in a combined cross analysis using related mouse strain crosses

    Cheverud, J. M., Lawson, H. A., Funk, R., Zhou, J., Blankenhorn, E. P. & Heber-Katz, E., Apr 2012, In: Heredity. 108, 4, p. 441-446 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    15 Scopus citations
  • High Fat Diet Induced Developmental Defects in the Mouse: Oocyte Meiotic Aneuploidy and Fetal Growth Retardation/Brain Defects

    Luzzo, K. M., Wang, Q., Purcell, S. H., Chi, M., Jimenez, P. T., Grindler, N., Schedl, T. & Moley, K. H., Nov 12 2012, In: PloS one. 7, 11, e49217.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    238 Scopus citations
  • Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature

    Rinkevich, Y., Mori, T., Sahoo, D., Xu, P. X., Bermingham, J. R. & Weissman, I. L., Dec 2012, In: Nature Cell Biology. 14, 12, p. 1251-1260 10 p.

    Research output: Contribution to journalArticlepeer-review

    125 Scopus citations
  • Impact of common variation in bone-related genes on type 2 diabetes and related traits

    Billings, L. K., Hsu, Y. H., Ackerman, R. J., Dupuis, J., Voight, B. F., Rasmussen-Torvik, L. J., Hercberg, S., Lathrop, M., Barnes, D., Langenberg, C., Hui, J., Fu, M., Bouatia-Naji, N., Lecoeur, C., An, P., Magnusson, P. K., Surakka, I., Ripatti, S., Christiansen, L., Dalgård, C., & 20 othersFolkersen, L., Grundberg, E., Eriksson, P., Kaprio, J., Kyvik, K. O., Pedersen, N. L., Borecki, I. B., Province, M. A., Balkau, B., Froguel, P., Shuldiner, A. R., Palmer, L. J., Wareham, N., Meneton, P., Johnson, T., Pankow, J. S., Karasik, D., Meigs, J. B., Kiel, D. P. & Florez, J. C., Aug 2012, In: Diabetes. 61, 8, p. 2176-2186 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • Improved models for transcription factor binding site identification using nonindependent interactions

    Zhao, Y., Ruan, S., Pandey, M. & Stormo, G. D., Jul 1 2012, In: Genetics. 191, 3, p. 781-790 10 p.

    Research output: Contribution to journalArticlepeer-review

    91 Scopus citations
  • Imputation of single-nucleotide polymorphisms in inbred mice using local phylogeny

    Wang, J. R., de Villena, F. P. M., Lawson, H. A., Cheverud, J. M., Churchill, G. A. & McMillan, L., Feb 2012, In: Genetics. 190, 2, p. 449-458 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    37 Scopus citations
  • Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

    Hartz, S. M., Short, S. E., Saccone, N. L., Culverhouse, R., Chen, L. S., Schwantes-An, T. H., Coon, H., Han, Y., Stephens, S. H., Sun, J., Chen, X., Ducci, F., Dueker, N., Franceschini, N., Frank, J., Geller, F., Guobjartsson, D., Hansel, N. N., Jiang, C., Keskitalo-Vuokko, K., & 132 othersLiu, Z., Lyytikäinen, L. P., Michel, M., Rawal, R., Rosenberger, A., Scheet, P., Shaffer, J. R., Teumer, A., Thompson, J. R., Vink, J. M., Vogelzangs, N., Wenzlaff, A. S., Wheeler, W., Xiao, X., Yang, B. Z., Aggen, S. H., Balmforth, A. J., Baumeister, S. E., Beaty, T., Bennett, S., Bergen, A. W., Boyd, H. A., Broms, U., Campbell, H., Chatterjee, N., Chen, J., Cheng, Y. C., Cichon, S., Couper, D., Cucca, F., Dick, D. M., Foroud, T., Furberg, H., Giegling, I., Gu, F., Hall, A. S., Hällfors, J., Han, S., Hartmann, A. M., Hayward, C., Heikkilä, K., Hewitt, J. K., Hottenga, J. J., Jensen, M. K., Jousilahti, P., Kaakinen, M., Kittner, S. J., Konte, B., Korhonen, T., Landi, M. T., Laatikainen, T., Leppert, M., Levy, S. M., Mathias, R. A., McNeil, D. W., Medland, S. E., Montgomery, G. W., Muley, T., Murray, T., Nauck, M., North, K., Pergadia, M., Polasek, O., Ramos, E. M., Ripatti, S., Risch, A., Ruczinski, I., Rudan, I., Salomaa, V., Schlessinger, D., Styrkársdóttir, U., Terracciano, A., Uda, M., Willemsen, G., Wu, X., Abecasis, G., Barnes, K., Bickeböller, H., Boerwinkle, E., Boomsma, D. I., Caporaso, N., Duan, J., Edenberg, H. J., Francks, C., Gejman, P. V., Gelernter, J., Grabe, H. J., Hops, H., Jarvelin, M. R., Viikari, J., Kähönen, M., Kendler, K. S., Lehtimäki, T., Levinson, D. F., Marazita, M. L., Marchini, J., Melbye, M., Mitchell, B. D., Murray, J. C., Nöthen, M. M., Penninx, B. W., Raitakari, O., Rietschel, M., Rujescu, D., Samani, N. J., Sanders, A. R., Schwartz, A. G., Shete, S., Shi, J., Spitz, M., Stefansson, K., Swan, G. E., Thorgeirsson, T., Völzke, H., Wei, Q., Wichmann, H. E., Amos, C. I., Breslau, N., Cannon, D. S., Ehringer, M., Grucza, R., Hatsukami, D., Heath, A., Johnson, E. O., Kaprio, J., Madden, P., Martin, N. G., Stevens, V. L., Stitzel, J. A., Weiss, R. B., Kraft, P. & Bierut, L. J., Aug 2012, In: Archives of General Psychiatry. 69, 8, p. 854-861 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    61 Scopus citations
  • Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

    Chasman, D. I., Fuchsberger, C., Pattaro, C., Teumer, A., Böger, C. A., Endlich, K., Olden, M., Chen, M. H., Tin, A., Taliun, D., Li, M., Gao, X., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C., O'Seaghdha, C. M., Glazer, N., Isaacs, A., Liu, C. T., & 144 othersSmith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Johnson, A. D., Gierman, H. J., Feitosa, M. F., Hwang, S. J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, Å., Tönjes, A., Dehghan, A., Lambert, J. C., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimäki, T., Esko, T., Deshmukh, H., Ulivi, S., Chu, A. Y., Murgia, F., Trompet, S., Imboden, M., Coassin, S., Pistis, G., Harris, T. B., Launer, L. J., Aspelund, T., Eiriksdottir, G., Mitchell, B. D., Boerwinkle, E., Schmidt, H., Cavalieri, M., Rao, M., Hu, F., Demirkan, A., Oostra, B. A., de Andrade, M., Turner, S. T., Ding, J., Andrews, J. S., Freedman, B. I., Giulianini, F., Koenig, W., Illig, T., Meisinger, C., Gieger, C., Zgaga, L., Zemunik, T., Boban, M., Minelli, C., Wheeler, H. E., Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Nöthlings, U., Jacobs, G., Biffar, R., Ernst, F., Homuth, G., Kroemer, H. K., Nauck, M., Stracke, S., Völker, U., Völzke, H., Kovacs, P., Stumvoll, M., Mägi, R., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Aulchenko, Y. S., Polasek, O., Hastie, N., Vitart, V., Helmer, C., Wang, J. J., Stengel, B., Ruggiero, D., Bergmann, S., Kähönen, M., Viikari, J., Nikopensius, T., Province, M., Ketkar, S., Colhoun, H., Doney, A., Robino, A., Krämer, B. K., Portas, L., Ford, I., Buckley, B. M., Adam, M., Thun, G. A., Paulweber, B., Haun, M., Sala, C., Mitchell, P., Ciullo, M., Kim, S. K., Vollenweider, P., Raitakari, O., Metspalu, A., Palmer, C., Gasparini, P., Pirastu, M., Jukema, J. W., Probst-Hensch, N. M., Kronenberg, F., Toniolo, D., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Ferrucci, L., Siscovick, D. S., van Duijn, C. M., Borecki, I. B., Kardia, S. L. R., Liu, Y., Curhan, G. C., Rudan, I., Gyllensten, U., Wilson, J. F., Franke, A., Pramstaller, P. P., Rettig, R., Prokopenko, I., Witteman, J., Hayward, C., Ridker, P. M., Parsa, A., Bochud, M., Heid, I. M., Kao, W. H. L., Fox, C. S. & Köttgen, A., Dec 2012, In: Human molecular genetics. 21, 24, p. 5329-5343 15 p.

    Research output: Contribution to journalArticlepeer-review

    53 Scopus citations
  • Interplay of genetic risk factors (CHRNA 5-CHRNA 3-CHRNB4) and cessation treatments in smoking cessation success

    Chen, L. S., Baker, T. B., Piper, M. E., Breslau, N., Cannon, D. S., Doheny, K. F., Gogarten, S. M., Johnson, E. O., Saccone, N. L., Wang, J. C., Weiss, R. B., Goate, A. M. & Bierut, L. J., Jul 1 2012, In: American Journal of Psychiatry. 169, 7, p. 735-742 8 p.

    Research output: Contribution to journalArticlepeer-review

    107 Scopus citations
  • IS-seq: a novel high throughput survey of in vivo IS6110 transposition in multiple Mycobacterium tuberculosis genomes

    Reyes, A., Sandoval, A., Cubillos-Ruiz, A., Varley, K. E., Hernández-Neuta, I., Samper, S., Martín, C., García, M. J., Ritacco, V., López, L., Robledo, J., Zambrano, M. M., Mitra, R. D. & Del Portillo, P., Jun 15 2012, In: BMC genomics. 13, 1, 249.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    23 Scopus citations
  • Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

    Scott, R. A., Lagou, V., Welch, R. P., Wheeler, E., Montasser, M. E., Luan, JA., MäGi, R., Strawbridge, R. J., Rehnberg, E., Gustafsson, S., Kanoni, S., Rasmussen-Torvik, L. J., Yengo, L., Lecoeur, C., Shungin, D., Sanna, S., Sidore, C., Johnson, P. C. D., Jukema, J. W., Johnson, T., & 194 othersMahajan, A., Verweij, N., Thorleifsson, G., Hottenga, J. J., Shah, S., Smith, A. V., Sennblad, B., Gieger, C., Salo, P., Perola, M., Timpson, N. J., Evans, D. M., Pourcain, B. S., Wu, Y., Andrews, J. S., Hui, J., Bielak, L. F., Zhao, W., Horikoshi, M., Navarro, P., Isaacs, A., O'Connell, J. R., Stirrups, K., Vitart, V., Hayward, C., Esko, T., Mihailov, E., Fraser, R. M., Fall, T., Voight, B. F., Raychaudhuri, S., Chen, H., Lindgren, C. M., Morris, A. P., Rayner, N. W., Robertson, N., Rybin, D., Liu, C. T., Beckmann, J. S., Willems, S. M., Chines, P. S., Jackson, A. U., Kang, H. M., Stringham, H. M., Song, K., Tanaka, T., Peden, J. F., Goel, A., Hicks, A. A., An, P., MüLler-Nurasyid, M., Franco-Cereceda, A., Folkersen, L., Marullo, L., Jansen, H., Oldehinkel, A. J., Bruinenberg, M., Pankow, J. S., North, K. E., Forouhi, N. G., Loos, R. J. F., Edkins, S., Varga, T. V., Hallmans, G., Oksa, H., Antonella, M., Nagaraja, R., Trompet, S., Ford, I., Bakker, S. J. L., Kong, A., Kumari, M., Gigante, B., Herder, C., Munroe, P. B., Caulfield, M., Antti, J., Mangino, M., Small, K., Miljkovic, I., Liu, Y., Atalay, M., Kiess, W., James, A. L., Rivadeneira, F., Uitterlinden, A. G., Palmer, C. N. A., Doney, A. S. F., Willemsen, G., Smit, J. H., Campbell, S., Polasek, O., Bonnycastle, L. L., Hercberg, S., Dimitriou, M., Bolton, J. L., Fowkes, G. R., Kovacs, P., LindströM, J., Zemunik, T., Bandinelli, S., Wild, S. H., Basart, H. V., Rathmann, W., Grallert, H., Maerz, W., Kleber, M. E., Boehm, B. O., Peters, A., Pramstaller, P. P., Province, M. A., Borecki, I. B., Hastie, N. D., Rudan, I., Campbell, H., Watkins, H., Farrall, M., Stumvoll, M., Ferrucci, L., Waterworth, D. M., Bergman, R. N., Collins, F. S., Tuomilehto, J., Watanabe, R. M., De Geus, E. J. C., Penninx, B. W., Hofman, A., Oostra, B. A., Psaty, B. M., Vollenweider, P., Wilson, J. F., Wright, A. F., Hovingh, G. K., Metspalu, A., Uusitupa, M., Magnusson, P. K. E., Kyvik, K. O., Kaprio, J., Price, J. F., Dedoussis, G. V., Deloukas, P., Meneton, P., Lind, L., Boehnke, M., Shuldiner, A. R., Van Duijn, C. M., Morris, A. D., Toenjes, A., Peyser, P. A., Beilby, J. P., KöRner, A., Kuusisto, J., Laakso, M., Bornstein, S. R., Schwarz, P. E. H., Lakka, T. A., Rauramaa, R., Adair, L. S., Smith, G. D., Spector, T. D., Illig, T., Faire, U. D., Hamsten, A., Gudnason, V., Kivimaki, M., Hingorani, A., Keinanen-Kiukaanniemi, S. M., Saaristo, T. E., Boomsma, D. I., Stefansson, K., Van Der Harst, P., Dupuis, J., Pedersen, N. L., Sattar, N., Harris, T. B., Cucca, F., Ripatti, S., Salomaa, V., Mohlke, K. L., Balkau, B., Froguel, P., Pouta, A., Jarvelin, M. R., Wareham, N. J., Bouatia-Naji, N., McCarthy, M. I., Franks, P. W., Meigs, J. B., Teslovich, T. M., Florez, J. C., Langenberg, C., Ingelsson, E., Prokopenko, I. & Barroso, I., Sep 2012, In: Nature Genetics. 44, 9, p. 991-1005 15 p.

    Research output: Contribution to journalArticlepeer-review

    603 Scopus citations
  • Medicago truncatula transporter database: A comprehensive database resource for M. truncatula transporters

    Miao, Z., Li, D., Zhang, Z., Dong, J., Su, Z. & Wang, T., Feb 6 2012, In: BMC genomics. 13, 1, 60.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

    Okada, Y., Sim, X., Go, M. J., Wu, J. Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S. C., Wong, T. Y., Liu, J., Young, T. L., Aung, T., Seielstad, M., Teo, Y. Y., Kim, Y. J., Lee, J. Y., Han, B. G., & 469 othersKang, D., Chen, C. H., Tsai, F. J., Chang, L. C., Fann, S. J., Mei, H., Rao, D. C., Hixson, J. E., Chen, S., Katsuya, T., Isono, M., Ogihara, T., Chambers, J. C., Zhang, W., Kooner, J. S., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y. T., Cho, Y. S., Tai, E. S., Tanaka, T., Chambers, J. C., Zhang, W., Lord, G. M., van der Harst, P., Lawlor, D. A., Sehmi, J. S., Gale, D. P., Wass, M. N., Ahmadi, K. R., Bakker, S. J., Beckmann, J., Bilo, H. J., Bochud, M., Brown, M. J., Caulfield, M. J., Connell, J. M., Cook, H. T., Cotlarciuc, I., Smith, G. D., de Silva, R., Deng, G., Devuyst, O., Dikkeschei, L. D., Dimkovic, N., Dockrell, M., Dominiczak, A., Ebrahim, S., Eggermann, T., Farrall, M., Ferrucci, L., Floege, J., Forouhi, N. G., Gansevoort, R. T., Han, X., Hedblad, B., van der Heide, J. J., Hepkema, B. G., Hernandez-Fuentes, M., Hypponen, E., Johnson, T., de Jong, P. E., Kleefstra, N., Lagou, V., Lapsley, M., Li, Y., Loos, R. J., Luan, J., Luttropp, K., Maréchal, C., Melander, O., Munroe, P. B., Nordfors, L., Parsa, A., Peltonen, L., Penninx, B. W., Perucha, E., Pouta, A., Prokopenko, I., Roderick, P. J., Ruokonen, A., Samani, N. J., Sanna, S., Schalling, M., Schlessinger, D., Schlieper, G., Seelen, M. A., Shuldiner, A. R., Sjögren, M., Smit, J. H., Snieder, H., Soranzo, N., Spector, T. D., Stenvinkel, P., Sternberg, M. J., Swaminathan, R., Tanaka, T., Ubink-Veltmaat, L. J., Uda, M., Vollenweider, P., Wallace, C., Waterworth, D., Zerres, K., Waeber, G., Wareham, N. J., Maxwell, P. H., McCarthy, M. I., Jarvelin, M. R., Mooser, V., Abecasis, G. R., Lightstone, L., Scott, J., Navis, G., Elliott, P., Kooner, J. S., Köttgen, A., Pattaro, C., Böger, C. A., Fuchsberger, C., Olden, M., Glazer, N. L., Parsa, A., Gao, X., Yang, Q., Smith, A. V., O'connell, J. R., Li, M., Schmidt, H., Tanaka, T., Isaacs, A., Ketkar, S., Hwang, S. J., Johnson, A. D., Dehghan, A., Teumer, A., Paré, G., Atkinson, E. J., Zeller, T., Lohman, K., Cornelis, M. C., Probst-Hensch, N. M., Kronenberg, F., Tönjes, A., Hayward, C., Aspelund, T., Eiriksdottir, G., Launer, L. J., Harris, T. B., Rampersaud, E., Mitchell, B. D., Arking, D. E., Boerwinkle, E., Struchalin, M., Cavalieri, M., Singleton, A., Giallauria, F., Metter, J., de Boer, I. H., Haritunians, T., Lumley, T., Siscovick, D., Psaty, B. M., Zillikens, M. C., Oostra, B. A., Feitosa, M., Province, M., de Andrade, M., Turner, S. T., Schillert, A., Ziegler, A., Wild, P. S., Schnabel, R. B., Wilde, S., Munzel, T. F., Leak, T. S., Illig, T., Klopp, N., Meisinger, C., Wichmann, H. E., Koenig, W., Zgaga, L., Zemunik, T., Kolcic, I., Minelli, C., Hu, F. B., Johansson, Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Schreiber, S., Aulchenko, Y. S., Felix, J. F., Rivadeneira, F., Uitterlinden, A. G., Hofman, A., Imboden, M., Nitsch, D., Brandstätter, A., Kollerits, B., Kedenko, L., Mägi, R., Stumvoll, M., Kovacs, P., Boban, M., Campbell, S., Endlich, K., Völzke, H., Kroemer, H. K., Nauck, M., Völker, U., Polasek, O., Vitart, V., Badola, S., Parker, A. N., Ridker, P. M., Kardia, S. L., Blankenberg, S., Liu, Y., Curhan, G. C., Franke, A., Rochat, T., Paulweber, B., Prokopenko, I., Wang, W., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Shlipak, M. G., van Duijn, C. M., Borecki, I., Krämer, B. K., Rudan, I., Gyllensten, U., Wilson, J. F., Witteman, J. C., Pramstaller, P. P., Rettig, R., Hastie, N., Chasman, D. I., Kao, W. H., Heid, I. M., Fox, C. S., Köttgen, A., Albrecht, E., Teumer, A., Vitart, V., Krumsiek, J., Hundertmark, C., Pistis, G., Ruggiero, D., O'seaghdha, M., Haller, T., Yang, Q., Tanaka, T., Johnson, A. D., Kutalik, Z., Smith, A. V., Shi, J., Struchalin, M., Middelberg, P. S., Brown, M. J., Gaffo, A. L., Pirastu, N., Li, G., Hayward, C., Zemunik, T., Huffman, J., Yengo, L., Zhao, J. H., Demirkan, A., Feitosa, M. F., Liu, X., Malerba, G., Lopez, L. M., Li, X., Kleber, M. E., Hicks, A. A., Nolte, I. M., Johansson, A., Murgia, F., Wild, S. H., Bakker, S. J., Peden, J. F., Dehghan, A., Steri, M., Tenesa, A., Lagou, V., Salo, P., Mangino, M., Rose, L. M., Lehtimäki, T., Woodward, O. M., Tin, A., Müller, C., Oldmeadow, C., Putku, M., Czamara, D., Kraft, P., Frogheri, L., Thun, G. A., Grotevendt, A., Gislason, G. K., Harris, T. B., Launer, L. J., McArdle, P., Shuldiner, A. R., Boerwinkle, E., Schmidt, H., Schallert, M., Martin, N. G., Montgomery, G. W., Kubo, M., Nakamura, Y., Tanaka, T., Jacobs, D. R., Liu, K., D'adamo, P., Ulivi, S., Rotter, J. I., Psaty, B. M., Vollenweider, P., Waeber, G., Campbell, S., Devuyst, O., Navaro, P., Kolcic, I., Hastie, N., Balkau, B., Froguel, P., Esko, T., Salumets, A., Khaw, K. T., Langenberg, C., Isaacs, A., Kraja, A., Zhang, Q., Wild, P. S., Scott, R. J., Holliday, E. G., Org, E., Viigimaa, M., Bandinelli, S., Metter, J. E., Lupo, A., Trabetti, E., Sorice, R., Döring, A., Lattka, E., Strauch, K., Theis, F., Waldenberger, M., Wichmann, H. E., Davies, G., Gow, A. J., Bruinenberg, M., Stolk, R. P., Kooner, J. S., Zhang, W., Winkelmann, B. R., Boehm, B. O., Lucae, S., Penninx, B. W., Smit, J. H., Curhan, G., Mudgal, P., Plenge, R. M., Portas, L., Persico, I., Kirin, M., Wilson, J. F., Mateo Leach, I., van Gilst, W. H., Goel, A., Ongen, H., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Imboden, M., von Eckardstein, A., Cucca, F., Nagaraja, R., Piras, M. G., Nauck, M., Schurmann, C., Budde, K., Ernst, F., Farrington, S. M., Theodoratou, E., Prokopenko, I., Stumvoll, M., Jula, A., Perola, M., Salomaa, V., Shin, S. Y., Spector, T. D., Sala, C., Ridker, P. M., Kähönen, M., Viikari, J., Hengstenberg, C., Nelson, C. P., Meschia, J. F., Nalls, M. A., Sharma, P., Singleton, A. B., Kamatani, N., Zeller, T., Burnier, M., Attia, J., Laan, M., Klopp, N., Hillege, H. L., Kloiber, S., Choi, H., Pirastu, M., Tore, S., Probst-Hensch, N. M., Völzke, H., Gudnason, V., Parsa, A., Schmidt, R., Whitfield, J. B., Fornage, M., Gasparini, P., Siscovick, D. S., Polasek, O., Campbell, H., Rudan, I., Bouatia-Naji, N., Metspalu, A., Loos, R. J., van Duijn, C. M., Borecki, I. B., Gambaro, G., Deary, I. J., Wolffenbuttel, B. H., Chambers, J. C., März, W., Pramstaller, P. P., Snieder, H., Gyllensten, U., Wright, A. F., Navis, G., Watkins, H., Witteman, J. C., Sanna, S., Schipf, S., Dunlop, M. G., Tönjes, A., Ripatti, S., Soranzo, N., Toniolo, D., Chasman, D. I., Raitakari, O., Kao, W. H., Ciullo, M., Fox, C. 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    Research output: Contribution to journalArticlepeer-review

    206 Scopus citations
  • Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration

    Misko, A. L., Sasaki, Y., Tuck, E., Milbrandt, J. & Baloh, R. H., Mar 21 2012, In: Journal of Neuroscience. 32, 12, p. 4145-4155 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    134 Scopus citations
  • Mouse transgenesis in a single locus with independent regulation for multiple fluorophores

    Dougherty, J. D., Zhang, J., Feng, H., Gong, S. & Heintz, N., Jul 12 2012, In: PloS one. 7, 7, e40511.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • Multiple peptidoglycan modification networks modulate helicobacter pylori's cell shape, motility, and colonization potential

    Sycuro, L. K., Wyckoff, T. J., Biboy, J., Born, P., Pincus, Z., Vollmer, W. & Salama, N. R., Mar 2012, In: PLoS pathogens. 8, 3, e1002603.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    102 Scopus citations
  • Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo

    Yadav, M., Louvet, C., Davini, D., Gardner, J. M., Martinez-Llordella, M., Bailey-Bucktrout, S., Anthony, B. A., Sverdrup, F. M., Head, R., Kuster, D. J., Ruminski, P., Weiss, D., Von Schack, D. & Bluestone, J. A., Sep 2012, In: Journal of Experimental Medicine. 209, 10, p. 1713-1722 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    491 Scopus citations
  • Next generation analytic tools for large scale genetic epidemiology studies of complex diseases

    Mechanic, L. E., Chen, H. S., Amos, C. I., Chatterjee, N., Cox, N. J., Divi, R. L., Fan, R., Harris, E. L., Jacobs, K., Kraft, P., Leal, S. M., McAllister, K., Moore, J. H., Paltoo, D. N., Province, M. A., Ramos, E. M., Ritchie, M. D., Roeder, K., Schaid, D. J., Stephens, M., & 7 othersThomas, D. C., Weinberg, C. R., Witte, J. S., Zhang, S., Zöllner, S., Feuer, E. J. & Gillanders, E. M., Jan 2012, In: Genetic Epidemiology. 36, 1, p. 22-35 14 p.

    Research output: Contribution to journalArticlepeer-review

    49 Scopus citations
  • Nicotine dependence and comorbid psychiatric disorders: Examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes

    Chen, L. S., Xian, H., Grucza, R. A., Saccone, N. L., Wang, J. C., Johnson, E. O., Breslau, N., Hatsukami, D. & Bierut, L. J., Jun 2012, In: Drug and Alcohol Dependence. 123, SUPPL.1, p. S42-S51

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals

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A., Kastelein, J. J. P., Schadt, E. E., Strachan, D. P., Reilly, M. P., Samani, N. J., Schunkert, H., Cupples, L. A., Sandhu, M. S., Ridker, P. M. & Munroe, P. B., Mar 29 2012, In: PLoS genetics. 8, 3, e1002607.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    331 Scopus citations
  • Novel Modeling of Combinatorial miRNA Targeting Identifies SNP with Potential Role in Bone Density

    Coronnello, C., Hartmaier, R., Arora, A., Huleihel, L., Pandit, K. V., Bais, A. S., Butterworth, M., Kaminski, N., Stormo, G. D., Oesterreich, S. & Benos, P. V., Dec 2012, In: PLoS computational biology. 8, 12, e1002830.

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    Open Access
    33 Scopus citations
  • Obesity-insulin targeted genes in the 3p26-25 region in human studies and LG/J and SM/J mice

    Kraja, A. T., Lawson, H. A., Arnett, D. K., Borecki, I. B., Broeckel, U., De Las Fuentes, L., Hunt, S. C., Province, M. A., Cheverud, J. & Rao, D. C., Aug 2012, In: Metabolism: clinical and experimental. 61, 8, p. 1129-1141 13 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Ontology-based federated data access to human studies information.

    Sim, I., Carini, S., Tu, S. W., Detwiler, L. T., Brinkley, J., Mollah, S. A., Burke, K., Lehmann, H. P., Chakraborty, S., Wittkowski, K. M., Pollock, B. H., Johnson, T. M., Huser, V. & Human Studies Database Project, S. D. P., 2012, In: Unknown Journal. 2012, p. 856-865 10 p.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer's disease Ibero-American cohort

    Jin, S. C., Pastor, P., Cooper, B., Cervantes, S., Benitez, B. A., Razquin, C., Goate, A. & Cruchaga, C., 2012, In: Alzheimer's Research and Therapy. 4, 4, 34.

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    83 Scopus citations
  • Population-based rare variant detection via pooled exome or custom hybridization capture with or without individual indexing

    Ramos, E., Levinson, B. T., Chasnoff, S., Hughes, A., Young, A. L., Thornton, K., Li, A., Vallania, F. L. M., Province, M. & Druley, T. E., Dec 6 2012, In: BMC genomics. 13, 1, 683.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    18 Scopus citations
  • Rapid and efficient human mutation detection using a bench-top next-generation DNA sequencer

    Jiang, Q., Turner, T., Sosa, M. X., Rakha, A., Arnold, S. & Chakravarti, A., Jan 2012, In: Human mutation. 33, 1, p. 281-289 9 p.

    Research output: Contribution to journalArticlepeer-review

    36 Scopus citations
  • Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence

    Haller, G., Druley, T., Vallania, F. L., Mitra, R. D., Li, P., Akk, G., Steinbach, J. H., Breslau, N., Johnson, E., Hatsukami, D., Stitzel, J., Bierut, L. J. & Goate, A. M., Feb 2012, In: Human molecular genetics. 21, 3, p. 647-655 9 p., ddr498.

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    Open Access
    47 Scopus citations
  • Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families

    Cruchaga, C., Chakraverty, S., Mayo, K., Vallania, F. L. M., Mitra, R. D., Faber, K., Williamson, J., Bird, T., Diaz-Arrastia, R., Foroud, T. M., Boeve, B. F., Graff-Radford, N. R., St. Jean, P., Lawson, M., Ehm, M. G., Mayeux, R., Goate, A. M. & for the NIA-LOAD - NCRAD Family Study Consortium, T. NIA-LOAD. . NCRAD. F. S. C., Feb 1 2012, In: PloS one. 7, 2, e31039.

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    Open Access
    218 Scopus citations
  • Rearranging exosites in noncatalytic domains can redirect the substrate specificity of ADAMTS proteases

    Gao, W., Zhu, J., Westfield, L. A., Tuley, E. A., Anderson, P. J. & Sadler, J. E., Aug 3 2012, In: Journal of Biological Chemistry. 287, 32, p. 26944-26952 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    21 Scopus citations
  • Recognition models to predict DNA-binding specificities of homeodomain proteins

    Christensen, R. G., Enuameh, M. S., Noyes, M. B., Brodsky, M. H., Wolfe, S. A. & Stormo, G. D., Jun 2012, In: Bioinformatics. 28, 12, p. i84-i89 bts202.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    29 Scopus citations