Department of Genetics

2023

Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy

Zuo, C., Baer, J. M., Knolhoff, B. L., Belle, J. I., Liu, X., de la Lastra, A. A., Fu, C., Hogg, G. D., Kingston, N. L., Breden, M. A., Dodhiawala, P. B., Zhou, D. C., Lander, V. E., James, C. A., Ding, L., Lim, K. H., Fields, R. C., Hawkins, W. G., Weber, J. D., Zhao, G., & 1 othersDenardo, D. G., Jun 5 2023, In: Journal of Experimental Medicine. 220, 6, e20212062.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

The Neurotoxin DSP-4 Dysregulates the Locus Coeruleus-Norepinephrine System and Recapitulates Molecular and Behavioral Aspects of Prodromal Neurodegenerative Disease

Iannitelli, A. F., Kelberman, M. A., Lustberg, D. J., Korukonda, A., McCann, K. E., Mulvey, B., Segal, A., Liles, L. C., Sloan, S. A., Dougherty, J. D. & Weinshenker, D., Jan 2023, In: eNeuro. 10, 1, ENEURO.0483-22.2022.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

The origins and functional effects of postzygotic mutations throughout the human life span

Rockweiler, N. B., Ramu, A., Nagirnaja, L., Wong, W. H., Noordam, M. J., Drubin, C. W., Huang, N., Miller, B., Todres, E. Z., Vigh-Conrad, K. A., Zito, A., Small, K. S., Ardlie, K. G., Cohen, B. A. & Conrad, D. F., Apr 14 2023, In: Science. 380, 6641, eabn7113.

Research output: Contribution to journal › Article › peer-review

The Relationship of Attention-Deficit/Hyperactivity Disorder With Posttraumatic Stress Disorder: A Two-Sample Mendelian Randomization and Population-Based Sibling Comparison Study

Post-Traumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium, Feb 15 2023, In: Biological Psychiatry. 93, 4, p. 362-369 8 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits

AMP-T2D Consortium, Apr 4 2023, In: Cell metabolism. 35, 4, p. 695-710.e6

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Uropathogenic Escherichia coli infection-induced epithelial trained immunity impacts urinary tract disease outcome

Russell, S. K., Harrison, J. K., Olson, B. S., Lee, H. J., O’Brien, V. P., Xing, X., Livny, J., Yu, L., Roberson, E. D. O., Bomjan, R., Fan, C., Sha, M., Estfanous, S., Amer, A. O., Colonna, M., Stappenbeck, T. S., Wang, T., Hannan, T. J. & Hultgren, S. J., May 2023, In: Nature microbiology. 8, 5, p. 875-888 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants

Young, K. L., Fisher, V., Deng, X., Brody, J. A., Graff, M., Lim, E., Lin, B. M., Xu, H., Amin, N., An, P., Aslibekyan, S., Fohner, A. E., Hidalgo, B., Lenzini, P., Kraaij, R., Medina-Gomez, C., Prokić, I., Rivadeneira, F., Sitlani, C., Tao, R., & 42 othersvan Rooij, J., Zhang, D., Broome, J. G., Buth, E. J., Heavner, B. D., Jain, D., Smith, A. V., Barnes, K., Boorgula, M. P., Chavan, S., Darbar, D., De Andrade, M., Guo, X., Haessler, J., Irvin, M. R., Kalyani, R. R., Kardia, S. L. R., Kooperberg, C., Kim, W., Mathias, R. A., McDonald, M. L., Mitchell, B. D., Peyser, P. A., Regan, E. A., Redline, S., Reiner, A. P., Rich, S. S., Rotter, J. I., Smith, J. A., Weiss, S., Wiggins, K. L., Yanek, L. R., Arnett, D., Heard-Costa, N. L., Leal, S., Lin, D., McKnight, B., Province, M., van Duijn, C. M., North, K. E., Cupples, L. A. & Liu, C. T., Jan 12 2023, In: Human Genetics and Genomics Advances. 4, 1, 100163.

Research output: Contribution to journal › Article › peer-review

Open Access

Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes

Choudhary, M. N. K., Quaid, K., Xing, X., Schmidt, H. & Wang, T., Dec 2023, In: Nature communications. 14, 1, 634.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2022

Activation domains can decouple the mean and noise of gene expression

Loell, K., Wu, Y., Staller, M. & Cohen, B., Jul 19 2022, In: Cell Reports. 40, 3, 111118.

Research output: Contribution to journal › Article › peer-review

Open Access

Activity-dependent translation dynamically alters the proteome of the perisynaptic astrocyte process

Sapkota, D., Kater, M. S. J., Sakers, K., Nygaard, K. R., Liu, Y., Koester, S. K., Fass, S. B., Lake, A. M., Khazanchi, R., Khankan, R. R., Krawczyk, M. C., Smit, A. B., Maloney, S. E., Verheijen, M. H. G., Zhang, Y. & Dougherty, J. D., Oct 18 2022, In: Cell Reports. 41, 3, 111474.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

A dominant negative variant of RAB5B disrupts maturation of surfactant protein B and surfactant protein C

Undiagnosed Diseases Network, Feb 8 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 6, e2105228119.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Age-Dependent Reduction in Asthmatic Pathology through Reprogramming of Postviral Inflammatory Responses

Hazan, G., Eubanks, A., Gierasch, C., Atkinson, J., Fox, C., Hernandez-Leyva, A., Rosen, A. L., Kau, A. L., Agapov, E., Alexander-Brett, J., Steinberg, D., Kelley, D., White, M., Byers, D., Wu, K., Keeler, S. P., Zhang, Y., Koenitzer, J. R., Eiden, E., Anderson, N., & 2 othersHoltzman, M. J. & Haspel, J., Mar 15 2022, In: Journal of Immunology. 208, 6, p. 1467-1482 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells

Dong, C., Fu, S., Karvas, R. M., Chew, B., Fischer, L. A., Xing, X., Harrison, J. K., Popli, P., Kommagani, R., Wang, T., Zhang, B. & Theunissen, T. W., Dec 2022, In: Nature communications. 13, 1, 2548.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

Million Veterans Program, Global Lipids Genetics Consortium, Locke, A. E., Wojczynski, M. K., Sung, Y. J., Rao, D. C. & Province, M. A., Aug 4 2022, In: American journal of human genetics. 109, 8, p. 1366-1387 22 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Ancestry adjustment improves genome-wide estimates of regional intolerance

Hayeck, T. J., Stong, N., Baugh, E., Dhindsa, R., Turner, T. N., Malakar, A., Mosbruger, T. L., Shaw, G. T. W., Duan, Y., Ionita-Laza, I., Goldstein, D. & Allen, A. S., May 31 2022, In: Genetics. 221, 2

Research output: Contribution to journal › Article › peer-review

Open Access

A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication

Shackleford, G. G., Marziali, L. N., Sasaki, Y., Claessens, A., Ferri, C., Weinstock, N. I., Rossor, A. M., Silvestri, N. J., Wilson, E. R., Hurley, E., Kidd, G. J., Manohar, S., Ding, D., Salvi, R. J., Laura Feltri, M., D’Antonio, M. & Wrabetz, L., Nov 9 2022, In: PLoS genetics. 18, 11, e1010477.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

A novel DPH5-related diphthamide-deficiency syndrome causing embryonic lethality or profound neurodevelopmental disorder

Undiagnosed Diseases Network, Jul 2022, In: Genetics in Medicine. 24, 7, p. 1567-1582 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

A phytobacterial TIR domain effector manipulates NAD⁺ to promote virulence

Eastman, S., Smith, T., Zaydman, M. A., Kim, P., Martinez, S., Damaraju, N., DiAntonio, A., Milbrandt, J., Clemente, T. E., Alfano, J. R. & Guo, M., Jan 2022, In: New Phytologist. 233, 2, p. 890-904 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Aqp4 stop codon readthrough facilitates amyloid-β clearance from the brain

Sapkota, D., Florian, C., Doherty, B. M., White, K. M., Reardon, K. M., Ge, X., Garbow, J., Yuede, C. M., Cirrito, J. R. & Dougherty, J., Sep 1 2022, In: Brain. 145, 9, p. 2982-2990 9 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

A quantitative metric of pioneer activity reveals that HNF4A has stronger in vivo pioneer activity than FOXA1

Hansen, J. L. & Cohen, B. A., Dec 2022, In: Genome biology. 23, 1, 221.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

A SARM1-mitochondrial feedback loop drives neuropathogenesis in a Charcot-Marie-Tooth disease type 2A rat model

Sato-Yamada, Y., Strickland, A., Sasaki, Y., Bloom, J., DiAntonio, A. & Milbrandt, J., Dec 1 2022, In: Journal of Clinical Investigation. 132, 23, e161566.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

A saturated map of common genetic variants associated with human height

23andMe Research Team, VA Million Veteran Program, DiscovEHR (DiscovEHR and MyCode Community Health Initiative), eMERGE (Electronic Medical Records and Genomics Network), Lifelines Cohort Study, The PRACTICAL Consortium & Understanding Society Scientific group, Oct 27 2022, In: Nature. 610, 7933, p. 704-712 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

65 Scopus citations

Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data

TOPMed Anthropometry Working Group & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Mar 2022, In: Nature Genetics. 54, 3, p. 263-273 11 p.

Research output: Contribution to journal › Article › peer-review

67 Scopus citations

Association of leukocyte telomere length with perceived physical fatigability

on behalf of the LLFS Research Group, Dec 2022, In: Experimental Gerontology. 170, 111988.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Biallelic AOPEP Loss-of-Function Variants Cause Progressive Dystonia with Prominent Limb Involvement

Zech, M., Kumar, K. R., Reining, S., Reunert, J., Tchan, M., Riley, L. G., Drew, A. P., Adam, R. J., Berutti, R., Biskup, S., Derive, N., Bakhtiari, S., Jin, S. C., Kruer, M. C., Bardakjian, T., Gonzalez-Alegre, P., Keller Sarmiento, I. J., Mencacci, N. E., Lubbe, S. J., Kurian, M. A., & 9 othersClot, F., Méneret, A., de Sainte Agathe, J. M., Fung, V. S. C., Vidailhet, M., Baumann, M., Marquardt, T., Winkelmann, J. & Boesch, S., Jan 2022, In: Movement Disorders. 37, 1, p. 137-147 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Biallelic Variants in the Ectonucleotidase ENTPD1 Cause a Complex Neurodevelopmental Disorder with Intellectual Disability, Distinct White Matter Abnormalities, and Spastic Paraplegia

Calame, D. G., Herman, I., Maroofian, R., Marshall, A. E., Donis, K. C., Fatih, J. M., Mitani, T., Du, H., Grochowski, C. M., Sousa, S. B., Gijavanekar, C., Bakhtiari, S., Ito, Y. A., Rocca, C., Hunter, J. V., Sutton, V. R., Emrick, L. T., Boycott, K. M., Lossos, A., Fellig, Y., & 45 othersPrus, E., Kalish, Y., Meiner, V., Suerink, M., Ruivenkamp, C., Muirhead, K., Saadi, N. W., Zaki, M. S., Bouman, A., Barakat, T. S., Skidmore, D. L., Osmond, M., Silva, T. O., Murphy, D., Karimiani, E. G., Jamshidi, Y., Jaddoa, A. G., Tajsharghi, H., Jin, S. C., Abbaszadegan, M. R., Ebrahimzadeh-Vesal, R., Hosseini, S., Alavi, S., Bahreini, A., Zarean, E., Salehi, M. M., Al-Sannaa, N. A., Zifarelli, G., Bauer, P., Robson, S. C., Coban-Akdemir, Z., Travaglini, L., Nicita, F., Jhangiani, S. N., Gibbs, R. A., Posey, J. E., Kruer, M. C., Kernohan, K. D., Morales Saute, J. A., Houlden, H., Vanderver, A., Elsea, S. H., Pehlivan, D., Marafi, D. & Lupski, J. R., Aug 2022, In: Annals of neurology. 92, 2, p. 304-321 18 p.

Research output: Contribution to journal › Article › peer-review

Brain ventricles as windows into brain development and disease

Duy, P. Q., Rakic, P., Alper, S. L., Butler, W. E., Walsh, C. A., Sestan, N., Geschwind, D. H., Jin, S. C. & Kahle, K. T., Jan 5 2022, In: Neuron. 110, 1, p. 12-15 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Capybara: A computational tool to measure cell identity and fate transitions

Kong, W., Fu, Y. C., Holloway, E. M., Garipler, G., Yang, X., Mazzoni, E. O. & Morris, S. A., Apr 7 2022, In: Cell Stem Cell. 29, 4, p. 635-649.e11

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Ciliary central apparatus structure reveals mechanisms of microtubule patterning

Gui, M., Wang, X., Dutcher, S. K., Brown, A. & Zhang, R., May 2022, In: Nature Structural and Molecular Biology. 29, 5, p. 483-492 10 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Clinical application of a scale to assess genomic healthcare empowerment (GEmS): Process and illustrative case examples

Undiagnosed Disease Network, Feb 2022, In: Journal of Genetic Counseling. 31, 1, p. 59-70 12 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients

Bloom, A. J., Mao, X., Strickland, A., Sasaki, Y., Milbrandt, J. & DiAntonio, A., Dec 2022, In: Molecular neurodegeneration. 17, 1, 1.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

CUT&Tag2for1: a modified method for simultaneous profiling of the accessible and silenced regulome in single cells

Janssens, D. H., Otto, D. J., Meers, M. P., Setty, M., Ahmad, K. & Henikoff, S., Dec 2022, In: Genome biology. 23, 1, 81.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling

Manik, M. K., Shi, Y., Li, S., Zaydman, M. A., Damaraju, N., Eastman, S., Smith, T. G., Gu, W., Masic, V., Mosaiab, T., Weagley, J. S., Hancock, S. J., Vasquez, E., Hartley-Tassell, L., Kargios, N., Maruta, N., Lim, B. Y. J., Burdett, H., Landsberg, M. J., Schembri, M. A., & 9 othersProkes, I., Song, L., Grant, M., DiAntonio, A., Nanson, J. D., Guo, M., Milbrandt, J., Ve, T. & Kobe, B., Sep 30 2022, In: Science. 377, 6614, eadc8969.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Defining hierarchical protein interaction networks from spectral analysis of bacterial proteomes

Zaydman, M. A., Little, A. S., Haro, F., Aksianiuk, V., Buchser, W. J., Diantonio, A., Gordon, J. I., Milbrandt, J. & Raman, A. S., 2022, In: eLife. 11, e74104.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

de novo variant calling identifies cancer mutation signatures in the 1000 Genomes Project

Ng, J. K., Vats, P., Fritz-Waters, E., Sarkar, S., Sams, E. I., Padhi, E. M., Payne, Z. L., Leonard, S., West, M. A., Prince, C., Trani, L., Jansen, M., Vacek, G., Samadi, M., Harkins, T. T., Pohl, C. & Turner, T. N., Dec 2022, In: Human mutation. 43, 12, p. 1979-1993 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Developmental Pathways Are Epigenetically Reprogrammed during Lung Cancer Brain Metastasis

Karlow, J. A., Devarakonda, S., Xing, X., Jang, H. S., Govindan, R., Watson, M. & Wang, T., Aug 1 2022, In: Cancer research. 82, 15, p. 2692-2703 12 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

Lifelines Cohort Study, DiscovEHR/MyCode study, VA Million Veteran Program, Wojczynski, M. K. & Province, M. A., Dec 1 2022, In: Communications Biology. 5, 1, 580.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Directed mutational scanning reveals a balance between acidic and hydrophobic residues in strong human activation domains

Staller, M., Ramirez, E., Kotha, S. R., Holehouse, A. S., Pappu, R. V. & Cohen, B. A., Apr 20 2022, In: Cell Systems. 13, 4, p. 334-345.e5

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Disentangling glial diversity in peripheral nerves at single-nuclei resolution

Yim, A. K. Y., Wang, P. L., Bermingham, J., Hackett, A., Strickland, A., Miller, T., Ly, C., Mitra, R. D. & Milbrandt, J., Feb 2022, In: Nature neuroscience. 25, 2, p. 238-251 14 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Distinct developmental and degenerative functions of SARM1 require NAD⁺ hydrolase activity

Brace, E. J., Essuman, K., Mao, X., Palucki, J., Sasaki, Y., Milbrandt, J. & DiAntonio, A., Jun 23 2022, In: PLoS genetics. 18, 6, e1010246.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Distinguishing Tumor Admixed in a Radiation Necrosis (RN) Background: ¹H and ²H MR With a Novel Mouse Brain-Tumor/RN Model

Ge, X., Song, K. H., Engelbach, J. A., Yuan, L., Gao, F., Dahiya, S., Rich, K. M., Ackerman, J. J. H. & Garbow, J. R., May 30 2022, In: Frontiers in Oncology. 12, 885480.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Endocannabinoid dysfunction in neurological disease: Neuro-ocular DAGLA-related syndrome

Undiagnosed Disease Network, Oct 1 2022, In: Brain. 145, 10, p. 3383-3390 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information

Maihofer, A. X., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Denckla, C. A., Ketema, E., Morey, R. A., Polimanti, R., Ratanatharathorn, A., Torres, K., Wingo, A. P., Zai, C. C., Aiello, A. E., Almli, L. M., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., & 161 othersAvdibegović, E., Borglum, A. D., Babić, D., Bækvad-Hansen, M., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J. I., Boks, M. P., Bolger, E. A., Bradley, B., Brashear, M., Breen, G., Bryant, R. A., Bustamante, A. C., Bybjerg-Grauholm, J., Calabrese, J. R., Caldas-de-Almeida, J. M., Chen, C. Y., Dale, A. M., Dalvie, S., Deckert, J., Delahanty, D. L., Dennis, M. F., Disner, S. G., Domschke, K., Duncan, L. E., Džubur Kulenović, A., Erbes, C. R., Evans, A., Farrer, L. A., Feeny, N. C., Flory, J. D., Forbes, D., Franz, C. E., Galea, S., Garrett, M. E., Gautam, A., Gelaye, B., Gelernter, J., Geuze, E., Gillespie, C. F., Goçi, A., Gordon, S. D., Guffanti, G., Hammamieh, R., Hauser, M. A., Heath, A. C., Hemmings, S. M. J., Hougaard, D. M., Jakovljević, M., Jett, M., Johnson, E. O., Jones, I., Jovanovic, T., Qin, X. J., Karstoft, K. I., Kaufman, M. L., Kessler, R. C., Khan, A., Kimbrel, N. A., King, A. P., Koen, N., Kranzler, H. R., Kremen, W. S., Lawford, B. R., Lebois, L. A. M., Lewis, C., Liberzon, I., Linnstaedt, S. D., Logue, M. W., Lori, A., Lugonja, B., Luykx, J. J., Lyons, M. J., Maples-Keller, J. L., Marmar, C., Martin, N. G., Maurer, D., Mavissakalian, M. R., McFarlane, A., McGlinchey, R. E., McLaughlin, K. A., McLean, S. A., Mehta, D., Mellor, R., Michopoulos, V., Milberg, W., Miller, M. W., Morris, C. P., Mors, O., Mortensen, P. B., Nelson, E. C., Nordentoft, M., Norman, S. B., O'Donnell, M., Orcutt, H. K., Panizzon, M. S., Peters, E. S., Peterson, A. L., Peverill, M., Pietrzak, R. H., Polusny, M. A., Rice, J. P., Risbrough, V. B., Roberts, A. L., Rothbaum, A. O., Rothbaum, B. O., Roy-Byrne, P., Ruggiero, K. J., Rung, A., Rutten, B. P. F., Saccone, N. L., Sanchez, S. E., Schijven, D., Seedat, S., Seligowski, A. V., Seng, J. S., Sheerin, C. M., Silove, D., Smith, A. K., Smoller, J. W., Sponheim, S. R., Stein, D. J., Stevens, J. S., Teicher, M. H., Thompson, W. K., Trapido, E., Uddin, M., Ursano, R. J., van den Heuvel, L. L., Van Hooff, M., Vermetten, E., Vinkers, C. H., Voisey, J., Wang, Y., Wang, Z., Werge, T., Williams, M. A., Williamson, D. E., Winternitz, S., Wolf, C., Wolf, E. J., Yehuda, R., Young, K. A., Young, R. M. D., Zhao, H., Zoellner, L. A., Haas, M., Lasseter, H., Provost, A. C., Salem, R. M., Sebat, J., Shaffer, R. A., Wu, T., Ripke, S., Daly, M. J., Ressler, K. J., Koenen, K. C., Stein, M. B. & Nievergelt, C. M., Apr 1 2022, In: Biological Psychiatry. 91, 7, p. 626-636 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Enzymatic transfer of acetate on histones from lysine reservoir sites to lysine activating sites

Mendoza, M., Egervari, G., Sidoli, S., Donahue, G., Alexander, D. C., Sen, P., Garcia, B. A. & Berger, S. L., Jan 2022, In: Science Advances. 8, 3, eabj5688.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Epigenomic analysis reveals prevalent contribution of transposable elements to cis-regulatory elements, tissue-specific expression, and alternative promoters in zebrafish

Lee, H. J., Hou, Y., Maeng, J. H., Shah, N. M., Chen, Y., Lawson, H. A., Yang, H., Yue, F. & Wang, T., Jul 2022, In: Genome research. 32, 8, p. 1424-1436 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Fluoxetine exposure throughout neurodevelopment differentially influences basilar dendritic morphology in the motor and prefrontal cortices

Maloney, S. E., Tabachnick, D. R., Jakes, C., Avdagic, S., Bauernfeind, A. L. & Dougherty, J. D., Dec 2022, In: Scientific reports. 12, 1, 7605.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

From karyotypes to precision genomics in 9p deletion and duplication syndromes

Sams, E. I., Ng, J. K., Tate, V., Claire Hou, Y. C., Cao, Y., Antonacci-Fulton, L., Belhassan, K., Neidich, J., Mitra, R. D., Cole, F. S., Dickson, P., Milbrandt, J. & Turner, T. N., Jan 13 2022, In: Human Genetics and Genomics Advances. 3, 1, 100081.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Functional analysis of a novel de novo variant in PPP5C associated with microcephaly, seizures, and developmental delay

Undiagnosed Diseases Network, May 2022, In: Molecular genetics and metabolism. 136, 1, p. 65-73 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Functional characterization of enhancer activity during a long terminal repeat's evolution

Du, A. Y., Zhuo, X., Sundaram, V., Jensen, N. O., Chaudhari, H. G., Saccone, N. L., Cohen, B. A. & Wang, T., Oct 2022, In: Genome research. 32, 10, p. 1840-1851 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Functional Connectivity of the Developing Mouse Cortex

Rahn, R. M., Brier, L. M., Bice, A. R., Reisman, M. D., Dougherty, J. D. & Culver, J. P., Apr 15 2022, In: Cerebral Cortex. 32, 8, p. 1755-1768 14 p.

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Department of Genetics

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