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  • 2013

    The PSEN1, p.E318G Variant Increases the Risk of Alzheimer's Disease in APOE-ε4 Carriers

    Benitez, B. A., Karch, C. M., Cai, Y., Jin, S. C., Cooper, B., Carrell, D., Bertelsen, S., Chibnik, L., Schneider, J. A., Bennett, D. A., Fagan, A. M., Holtzman, D., Morris, J. C., Goate, A. M. & Cruchaga, C., Aug 2013, In: PLoS genetics. 9, 8, e1003685.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    50 Scopus citations

  • Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation

    Dalal, J., Roh, J. H., Maloney, S. E., Akuffo, A., Shah, S., Yuan, H., Wamsley, B., Jones, W. B., Strong, C. D. G., Gray, P. A., Holtzman, D. M., Heintz, N. & Dougherty, J. D., Mar 1 2013, In: Genes and Development. 27, 5, p. 565-578 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    74 Scopus citations

  • Transposable Elements Are Major Contributors to the Origin, Diversification, and Regulation of Vertebrate Long Noncoding RNAs

    Kapusta, A., Kronenberg, Z., Lynch, V. J., Zhuo, X., Ramsay, L. A., Bourque, G., Yandell, M. & Feschotte, C., Apr 2013, In: PLoS genetics. 9, 4, e1003470.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    470 Scopus citations

  • TREM2 is associated with the risk of Alzheimer's disease in Spanish population

    Benitez, B. A., Cooper, B., Pastor, P., Jin, S. C., Lorenzo, E., Cervantes, S. & Cruchaga, C., Jun 2013, In: Neurobiology of Aging. 34, 6, p. 1711.e15-1711.e17

    Research output: Contribution to journal › Article › peer-review

    125 Scopus citations

  • Ultralow protein adsorbing coatings from clickable PEG nanogel solutions: Benefits of attachment under salt-induced phase separation conditions and comparison with PEG/albumin nanogel coatings

    Donahoe, C. D., Cohen, T. L., Li, W., Nguyen, P. K., Fortner, J. D., Mitra, R. D. & Elbert, D. L., Mar 26 2013, In: Langmuir. 29, 12, p. 4128-4139 12 p.

    Research output: Contribution to journal › Article › peer-review

    27 Scopus citations

  • Understanding Variation in Transcription Factor Binding by Modeling Transcription Factor Genome-Epigenome Interactions

    Chen, C. C., Xiao, S., Xie, D., Cao, X., Song, C. X., Wang, T., He, C. & Zhong, S., Dec 2013, In: PLoS computational biology. 9, 12, e1003367.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    23 Scopus citations

  • Using defined finger-finger interfaces as units of assembly for constructing zinc-finger nucleases

    Zhu, C., Gupta, A., Hall, V. L., Rayla, A. L., Christensen, R. G., Dake, B., Lakshmanan, A., Kuperwasser, C., Stormo, G. D. & Wolfe, S. A., Feb 2013, In: Nucleic acids research. 41, 4, p. 2455-2465 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    26 Scopus citations

  • Whole Genome Sequencing Identifies a Deletion in Protein Phosphatase 2A That Affects Its Stability and Localization in Chlamydomonas reinhardtii

    Lin, H., Miller, M. L., Granas, D. M. & Dutcher, S. K., Sep 2013, In: PLoS genetics. 9, 9, e1003841.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    42 Scopus citations

  • X-linked markers in the Duchenne muscular dystrophy gene associated with oral clefts

    Patel, P. J., Beaty, T. H., Ruczinski, I., Murray, J. C., Marazita, M. L., Munger, R. G., Hetmanski, J. B., Wu, T., Murray, T., Rose, M., Redett, R. J., Jin, S. C., Lie, R. T., Wu-Chou, Y. H., Wang, H., Ye, X., Yeow, V., Chong, S., Jee, S. H., Shi, B., & 1 othersScott, A. F., Apr 2013, In: European Journal of Oral Sciences. 121, 2, p. 63-68 6 p.

    Research output: Contribution to journal › Article › peer-review

    9 Scopus citations
  • 2014

    A comparative encyclopedia of DNA elements in the mouse genome

    Yue, F., Cheng, Y., Breschi, A., Vierstra, J., Wu, W., Ryba, T., Sandstrom, R., Ma, Z., Davis, C., Pope, B. D., Shen, Y., Pervouchine, D. D., Djebali, S., Thurman, R. E., Kaul, R., Rynes, E., Kirilusha, A., Marinov, G. K., Williams, B. A., Trout, D., & 117 othersAmrhein, H., Fisher-Aylor, K., Antoshechkin, I., DeSalvo, G., See, L. H., Fastuca, M., Drenkow, J., Zaleski, C., Dobin, A., Prieto, P., Lagarde, J., Bussotti, G., Tanzer, A., Denas, O., Li, K., Bender, M. A., Zhang, M., Byron, R., Groudine, M. T., McCleary, D., Pham, L., Ye, Z., Kuan, S., Edsall, L., Wu, Y. C., Rasmussen, M. D., Bansal, M. S., Kellis, M., Keller, C. A., Morrissey, C. S., Mishra, T., Jain, D., Dogan, N., Harris, R. S., Cayting, P., Kawli, T., Boyle, A. P., Euskirchen, G., Kundaje, A., Lin, S., Lin, Y., Jansen, C., Malladi, V. S., Cline, M. S., Erickson, D. T., Kirkup, V. M., Learned, K., Sloan, C. A., Rosenbloom, K. R., De Sousa, B. L., Beal, K., Pignatelli, M., Flicek, P., Lian, J., Kahveci, T., Lee, D., Kent, W. J., Santos, M. R., Herrero, J., Notredame, C., Johnson, A., Vong, S., Lee, K., Bates, D., Neri, F., Diegel, M., Canfield, T., Sabo, P. J., Wilken, M. S., Reh, T. A., Giste, E., Shafer, A., Kutyavin, T., Haugen, E., Dunn, D., Reynolds, A. P., Neph, S., Humbert, R., Hansen, R. S., De Bruijn, M., Selleri, L., Rudensky, A., Josefowicz, S., Samstein, R., Eichler, E. E., Orkin, S. H., Levasseur, D., Papayannopoulou, T., Chang, K. H., Skoultchi, A., Gosh, S., Disteche, C., Treuting, P., Wang, Y., Weiss, M. J., Blobel, G. A., Cao, X., Zhong, S., Wang, T., Good, P. J., Lowdon, R. F., Adams, L. B., Zhou, X. Q., Pazin, M. J., Feingold, E. A., Wold, B., Taylor, J., Mortazavi, A., Weissman, S. M., Stamatoyannopoulos, J. A., Snyder, M. P., Guigo, R., Gingeras, T. R., Gilbert, D. M., Hardison, R. C., Beer, M. A. & Ren, B., Nov 20 2014, In: Nature. 515, 7527, p. 355-364 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1120 Scopus citations

  • A Computational Framework for Analyzing Stochasticity in Gene Expression

    Sherman, M. S. & Cohen, B. A., May 2014, In: PLoS computational biology. 10, 5, e1003596.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    20 Scopus citations

  • Adjusting family relatedness in data-driven burden test of rare variants

    Zhang, Q., Wang, L., Koboldt, D., Boreki, I. B. & Province, M. A., Dec 1 2014, In: Genetic Epidemiology. 38, 8, p. 722-727 6 p.

    Research output: Contribution to journal › Article › peer-review

    6 Scopus citations

  • Adult height and prevalence of coronary artery calcium the national heart, lung, and blood institute family heart study

    Miedema, M. D., Petrone, A. B., Arnett, D. K., Dodson, J. A., Carr, J. J., Pankow, J. S., Hunt, S. C., Province, M. A., Kraja, A., Gaziano, J. M. & Djousse, L., Jan 2014, In: Circulation: Cardiovascular Imaging. 7, 1, p. 52-57 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    10 Scopus citations

  • Age, Gender, and Cancer but Not Neurodegenerative and Cardiovascular Diseases Strongly Modulate Systemic Effect of the Apolipoprotein E4 Allele on Lifespan

    Kulminski, A. M., Arbeev, K. G., Culminskaya, I., Arbeeva, L., Ukraintseva, S. V., Stallard, E., Christensen, K., Schupf, N., Province, M. A. & Yashin, A. I., Jan 2014, In: PLoS genetics. 10, 1, e1004141.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    43 Scopus citations

  • A GSK-3β inhibitor protects against radiation necrosis in mouse brain

    Jiang, X., Perez-Torres, C. J., Thotala, D., Engelbach, J. A., Yuan, L., Cates, J., Gao, F., Drzymala, R. E., Rich, K., Schmidt, R. E., Ackerman, J. J. H., Hallahan, D. E. & Garbow, J. R., Jul 15 2014, In: International Journal of Radiation Oncology Biology Physics. 89, 4, p. 714-721 8 p.

    Research output: Contribution to journal › Article › peer-review

    20 Scopus citations

  • Allosteric activation of ADAMTS13 by von Willebrand factor

    Muia, J., Zhu, J., Gupta, G., Haberichter, S. L., Friedman, K. D., Feys, H. B., Deforche, L., Vanhoorelbeke, K., Westfield, L. A., Roth, R., Tolia, N. H., Heuser, J. E. & Sadler, J. E., Dec 30 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 52, p. 18584-18589 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    101 Scopus citations

  • An improved predictive recognition model for Cys2-His 2 zinc finger proteins

    Gupta, A., Christensen, R. G., Bell, H. A., Goodwin, M., Patel, R. Y., Pandey, M., Enuameh, M. S., Rayla, A. L., Zhu, C., Thibodeau-Beganny, S., Brodsky, M. H., Joung, J. K., Wolfe, S. A. & Stormo, G. D., Apr 2014, In: Nucleic acids research. 42, 8, p. 4800-4812 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    57 Scopus citations

  • Anti-VEGF antibodies mitigate the development of radiation necrosis in mouse brain

    Jiang, X., Engelbach, J. A., Yuan, L., Cates, J., Gao, F., Drzymala, R. E., Hallahan, D. E., Rich, K., Schmidt, R. E., Ackerman, J. J. H. & Garbow, J. R., May 15 2014, In: Clinical Cancer Research. 20, 10, p. 2695-2702 8 p.

    Research output: Contribution to journal › Article › peer-review

    63 Scopus citations

  • A Requirement for ERK-Dependent Dicer Phosphorylation in Coordinating Oocyte-to-Embryo Transition in C.elegans

    Drake, M., Furuta, T., Suen, K. M., Gonzalez, G., Liu, B., Kalia, A., Ladbury, J. E., Fire, A. Z., Skeath, J. B. & Arur, S., Dec 8 2014, In: Developmental cell. 31, 5, p. 614-628 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    56 Scopus citations

  • Beyond cigarettes per day: A genome-wide association study of the biomarker carbon monoxide

    Bloom, A. J., Hartz, S. M., Baker, T. B., Chen, L. S., Piper, M. E., Fox, L., Martinez, M., Hatsukami, D., Johnson, E. O., Laurie, C. C., Saccone, N. L., Goate, A. & Bierut, L. J., Sep 1 2014, In: Annals of the American Thoracic Society. 11, 7, p. 1003-1010 8 p.

    Research output: Contribution to journal › Article › peer-review

    31 Scopus citations

  • Causal Variation in Yeast Sporulation Tends to Reside in a Pathway Bottleneck

    Lorenz, K. & Cohen, B. A., Sep 1 2014, In: PLoS genetics. 10, 9

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations

  • CellNet: Network biology applied to stem cell engineering

    Cahan, P., Li, H., Morris, S. A., Lummertz Da Rocha, E., Daley, G. Q. & Collins, J. J., Aug 14 2014, In: Cell. 158, 4, p. 903-915 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    383 Scopus citations

  • Cell type-specific expression analysis to identify putative cellular mechanisms for neurogenetic disorders

    Xu, X., Wells, A. B., O'Brien, D. R., Nehorai, A. & Dougherty, J. D., 2014, In: Journal of Neuroscience. 34, 4, p. 1420-1431 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    175 Scopus citations

  • Classical Flt3L-dependent dendritic cells control immunity to protein vaccine

    Anandasabapathy, N., Feder, R., Mollah, S., Tse, S. W., Longhi, M. P., Mehandru, S., Matos, I., Cheong, C., Ruane, D., Brane, L., Teixeira, A., Dobrin, J., Mizenina, O., Park, C. G., Meredith, M., Clausen, B. E., Nussenzweig, M. C. & Steinman, R. M., 2014, In: Journal of Experimental Medicine. 211, 9, p. 1875-1891 17 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    79 Scopus citations

  • Clinical and computed tomographic predictors of chronic bronchitis in COPD: A cross sectional analysis of the COPDGene study

    Kim, V., Davey, A., Comellas, A. P., Han, M. K., Washko, G., Martinez, C. H., Lynch, D., Lee, J. H., Silverman, E. K., Crapo, J. D., Make, B. J., Criner, G. J., Farzadegan, H., Bragan, S., Cayetano, S., Curtis, J., Kazerooni, E., Hanania, N., Alapat, P., Bandi, V., & 168 othersGuntupalli, K., Guy, E., Mallampalli, A., Trinh, C., Atik, M., Al-Azzawi, H., Willis, M., Pinero, S., Fahr, L., Nachiappan, A., Bray, C., Frigini, L. A., Farinas, C., Katz, D., Freytes, J., Marciel, A. M., DeMeo, D., Hersh, C., Jacobson, F., Hatabu, H., Clarke, P., Gill, R., Hunsaker, A., Trotman-Dickenson, B., Madan, R., Barr, R. G., Thomashow, B., Austin, J., D'Souza, B., MacIntyre, N., Washington, L., McAdams, H. P., Rosiello, R., Bresnahan, T., Bradley, J., Kuong, S., Meller, S., Roland, S., McEvoy, C., Tashjian, J., Wise, R., Hansel, N., Brown, R., Diette, G., Horton, K., Casaburi, R., Porszasz, J., Fischer, H., Budoff, M., Rambod, M., Sharafkhaneh, A., Kamal, H., Darvishi, R., Niewoehner, D., Anderson, Q., Rice, K., Caine, A., Foreman, M., Westney, G., Berkowitz, E., Bowler, R., Schroeder, J., Hale, V., Armstrong, J., Dyer, D., Chung, J., Cox, C., Marchetti, N., Satti, A., Mamary, A. J., Steiner, R., Dass, C., Cone, L., Bailey, W., Dransfield, M., Wells, M., Bhatt, S., Nath, H., Singh, S., Ramsdell, J., Friedman, P., Cornellas, A., Newell, J., van Beek, E. J. R., Martinez, F., Wendt, C., Allen, T., Sciurba, F., Weissfeld, J., Fuhrman, C., Bon, J., Hooper, D., Anzueto, A., Adams, S., Orozco, C., Ruiz, M., Mumbower, A., Kruger, A., Restrepo, C., Lane, M., Akhavan, J., Al Qaisi, M., Beaty, T., Black-Shinn, J., Bleecker, E. R., Bowler, R. P., Bratschie, S., Castaldic, P. J., Cho, M., Cox, C. W., Coxson, H. O., Croxton, T., Crystal, R. G., Curtis, J. L., Cusick, D., DeMeo, D. L., Dy, J. G., Everett, D., Foreman, M. G., Gan, W., Ginsburg, S., Hansel, N. N., Hardin, M. E., Hersh, C. P., Hetmanski, J., Hoffman, E. A., Hogg, J. C., Hokanson, J., Hokanson, J. E., Jensen, R., Jose Estepar, R. S., Judy, P. F., Kinney, G., Kluiber, A., Knowles, R., Laird, N., Lange, C., Lantz, R., Lutz, S. M., Mattheisen, M., McDonaldc, M. L., McKenzie, A., Melanson, S., Newell, J. D., Parker, M. M., Plant, R., Postow, L., Prieto, D., Province, M. A., Regan, E. A., Reilly, J. J., Rennard, S. I., Rossc, J., Santorico, S., Schroeder, J. D., Sieren, J., Sitek, A., Stepp, L., Stinson, D., Sutherland, E. R., Thomas, D. C., Walsh, J. W., Wan, E. S., Williams, A., Wilson, C., Zach, J., Zhou, J. & van Beek, E., Apr 27 2014, In: Respiratory Research. 15, 1, 52.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    80 Scopus citations

  • Coding variants in TREM2 increase risk for Alzheimer's disease

    Jin, S. C., Benitez, B. A., Karch, C. M., Cooper, B., Skorupa, T., Carrell, D., Norton, J. B., Hsu, S., Harari, O., Cai, Y., Bertelsen, S., Goate, A. M. & Cruchaga, C., Nov 1 2014, In: Human molecular genetics. 23, 21, p. 5838-5846 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    214 Scopus citations

  • Common genetic variants on 6q24 associated with exceptional episodic memory performance in the elderly

    Long Life Family Study, Dec 1 2014, In: JAMA Neurology. 71, 12, p. 1514-1519 6 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations

  • Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers

    Zhang, B., Xing, X. Y., Li, J., Lowdon, R. F., Zhou, Y., Lin, N., Zhang, B., Sundaram, V., Chiappinelli, K. B., Hagemann, I. S., Mutch, D. G., Goodfellow, P. J. & Wang, T., Oct 6 2014, In: BMC genomics. 15, 1, 868.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    50 Scopus citations

  • Congenitally acquired persistent lymphocytic choriomeningitis viral infection reduces neuronal progenitor pools in the adult hippocampus and subventricular zone

    Sun, T., Vasek, M. J. & Klein, R. S., May 6 2014, In: PloS one. 9, 5, e96442.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    16 Scopus citations

  • CYP2D6 Genotype and Adjuvant Tamoxifen: Meta-Analysis of Heterogeneous Study Populations

    Province, M. A., Goetz, M. P., Brauch, H., Flockhart, D. A., Hebert, J. M., Whaley, R., Suman, V. J., Schroth, W., Winter, S., Zembutsu, H., Mushiroda, T., Newman, W. G., Lee, M. T. M., Ambrosone, C. B., Beckmann, M. W., Choi, J. Y., Dieudonné, A. S., Fasching, P. A., Ferraldeschi, R., Gong, L., & 44 othersHaschke-Becher, E., Howell, A., Jordan, L. B., Hamann, U., Kiyotani, K., Krippl, P., Lambrechts, D., Latif, A., Langsenlehner, U., Lorizio, W., Neven, P., Nguyen, A. T., Park, B. W., Purdie, C. A., Quinlan, P., Renner, W., Schmidt, M., Schwab, M., Shin, J. G., Stingl, J. C., Wegman, P., Wingren, S., Wu, A. H. B., Ziv, E., Zirpoli, G., Thompson, A. M., Jordan, V. C., Nakamura, Y., Altman, R. B., Ames, M. M., Weinshilboum, R. M., Eichelbaum, M., Ingle, J. N., Klein, T. E., Boländer, J., Ulmer, H. U., Fischer-Bosch, M., Fritz, P., Simon, W., Bryan, Y., Strick, R., Koelbl, H., Ambrosone, C. A. & H, E. Z., Feb 1 2014, In: Clinical pharmacology and therapeutics. 95, 2, p. 216-227 12 p.

    Research output: Contribution to journal › Article › peer-review

    148 Scopus citations

  • Cytochrome p450 gene variants, race, and mortality among clopidogrel-treated patients after acute myocardial infarction

    Cresci, S., Depta, J. P., Lenzini, P. A., Li, A. Y., Lanfear, D. E., Province, M. A., Spertus, J. A. & Bach, R. G., Jun 2014, In: Circulation: Cardiovascular Genetics. 7, 3, p. 277-286 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    44 Scopus citations

  • Defining cellular identity through network biology

    Cahan, P., Morris, S. A., Collins, J. J. & Daley, G. Q., Nov 1 2014, In: Cell Cycle. 13, 21, p. 3313-3314 2 p., A1.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Wood, A. R., Esko, T., Yang, J., Vedantam, S., Pers, T. H., Gustafsson, S., Chu, A. Y., Estrada, K., Luan, JA., Kutalik, Z., Amin, N., Buchkovich, M. L., Croteau-Chonka, D. C., Day, F. R., Duan, Y., Fall, T., Fehrmann, R., Ferreira, T., Jackson, A. U., Karjalainen, J., & 425 othersLo, K. S., Locke, A., Mägi, R., Mihailov, E., Porcu, E., Randall, J. C., Scherag, A., Vinkhuyzen, A. A. E., Westra, H. J., Winkler, T. W., Workalemahu, T., Zhao, J. H., Absher, D., Albrecht, E., Anderson, D., Baron, J., Beekman, M., Demirkan, A., Ehret, G. B., Feenstra, B., Feitosa, M. F., Fischer, K., Fraser, R. M., Goel, A., Gong, J., Justice, A. E., Kanoni, S., Kleber, M. E., Kristiansson, K., Lim, U., Lotay, V., Lui, J. C., Mangino, M., Leach, I. M., Medina-Gomez, C., Nalls, M. A., Nyholt, D. R., Palmer, C. D., Pasko, D., Pechlivanis, S., Prokopenko, I., Ried, J. S., Ripke, S., Shungin, D., Stancáková, A., Strawbridge, R. J., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., Van Der Laan, S. W., Van Setten, J., Van Vliet-Ostaptchouk, J. V., Wang, Z., Yengo, L., Zhang, W., Afzal, U., Ärnlöv, J., Arscott, G. M., Bandinelli, S., Barrett, A., Bellis, C., Bennett, A. J., Berne, C., Blüher, M., Bolton, J. L., Böttcher, Y., Boyd, H. A., Bruinenberg, M., Buckley, B. M., Buyske, S., Caspersen, I. H., Chines, P. S., Clarke, R., Claudi-Boehm, S., Cooper, M., Daw, E. W., De Jong, P. A., Deelen, J., Delgado, G., Denny, J. C., Dhonukshe-Rutten, R., Dimitriou, M., Doney, A. S. F., Dörr, M., Eklund, N., Eury, E., Folkersen, L., Garcia, M. E., Geller, F., Giedraitis, V., Go, A. S., Grallert, H., Grammer, T. B., Gräßler, J., Grönberg, H., De Groot, L. C. P. G. M., Groves, C. J., Haessler, J., Hall, P., Haller, T., Hallmans, G., Hannemann, A., Hartman, C. A., Hassinen, M., Hayward, C., Heard-Costa, N. L., Helmer, Q., Hemani, G., Henders, A. K., Hillege, H. L., Hlatky, M. A., Hoffmann, W., Hoffmann, P., Holmen, O., Houwing-Duistermaat, J. J., Illig, T., Isaacs, A., James, A. L., Jeff, J., Johansen, B., Johansson, Å., Jolley, J., Juliusdottir, T., Junttila, J., Kho, A. N., Kinnunen, L., Klopp, N., Kocher, T., Kratzer, W., Lichtner, P., Lind, L., Lindström, J., Lobbens, S., Lorentzon, M., Lu, Y., Lyssenko, V., Magnusson, P. K. E., Mahajan, A., Maillard, M., McArdle, W. L., McKenzie, C. A., McLachlan, S., McLaren, P. J., Menni, C., Merger, S., Milani, L., Moayyeri, A., Monda, K. L., Morken, M. A., Müller, G., Müller-Nurasyid, M., Musk, A. W., Narisu, N., Nauck, M., Nolte, I. M., Nöthen, M. M., Oozageer, L., Pilz, S., Rayner, N. W., Renstrom, F., Robertson, N. R., Rose, L. M., Roussel, R., Sanna, S., Scharnagl, H., Scholtens, S., Schumacher, F. R., Schunkert, H., Scott, R. A., Sehmi, J., Seufferlein, T., Shi, J., Silventoinen, K., Smit, J. H., Smith, A. V., Smolonska, J., Stanton, A. V., Stirrups, K., Stott, D. J., Stringham, H. M., Sundström, J., Swertz, M. A., Syvänen, A. C., Tayo, B. O., Thorleifsson, G., Tyrer, J. P., Van Dijk, S., Van Schoor, N. 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J., Watkins, H., Wichmann, H. E., Wilson, J. F., Zanen, P., Deloukas, P., Heid, I. M., Lindgren, C. M., Mohlke, K. L., Speliotes, E. K., Thorsteinsdottir, U., Barroso, I., Fox, C. S., North, K. E., Strachan, D. P., Beckmann, J. S., Berndt, S. I., Boehnke, M., Borecki, I. B., McCarthy, M. I., Metspalu, A., Stefansson, K., Uitterlinden, A. G., Van Duijn, C. M., Franke, L., Willer, C. J., Price, A. L., Lettre, G., Loos, R. J. F., Weedon, M. N., Ingelsson, E., O'Connell, J. R., Abecasis, G. R., Chasman, D. I., Goddard, M. E., Visscher, P. M., Hirschhorn, J. N. & Frayling, T. M., Nov 5 2014, In: Nature Genetics. 46, 11, p. 1173-1186 14 p.

    Research output: Contribution to journal › Article › peer-review

    1264 Scopus citations

  • Discrimination between thermodynamic models of cis-regulation using transcription factor occupancy data

    Zeigler, R. D. & Cohen, B. A., Feb 2014, In: Nucleic acids research. 42, 4, p. 2224-2234 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • Discriminative motif optimization based on perceptron training

    Patel, R. Y. & Stormo, G. D., Apr 1 2014, In: Bioinformatics. 30, 7, p. 941-948 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    18 Scopus citations

  • Dissecting engineered cell types and enhancing cell fate conversion via Cellnet

    Morris, S. A., Cahan, P., Li, H., Zhao, A. M., San Roman, A. K., Shivdasani, R. A., Collins, J. J. & Daley, G. Q., Aug 14 2014, In: Cell. 158, 4, p. 889-902 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    190 Scopus citations

  • DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease

    the COPDGene and ECLIPSE Investigators, Aug 20 2014, In: Respiratory Research. 15, 1, 97.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    19 Scopus citations

  • Fine-mapping quantitative trait loci affecting murine external ear tissue regeneration in the LG/J by SM/J advanced intercross line

    Cheverud, J. M., Lawson, H. A., Bouckaert, K., Kossenkov, A. V., Showe, L. C., Cort, L., Blankenhorn, E. P., Bedelbaeva, K., Gourevitch, D., Zhang, Y. & Heber-Katz, E., May 2014, In: Heredity. 112, 5, p. 508-518 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    22 Scopus citations

  • Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells

    Mollah, S. A., Dobrin, J. S., Feder, R. E., Tse, S. W., Matos, I. G., Cheong, C., Steinman, R. M. & Anandasabapathy, N., 2014, In: Journal of Investigative Dermatology. 134, 5, p. 1265-1275 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    27 Scopus citations

  • FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals

    Qi, Q., Kilpeläinen, T. O., Downer, M. K., Tanaka, T., Smith, C. E., Sluijs, I., Sonestedt, E., Chu, A. Y., Renström, F., Lin, X., Ängquist, L. H., Huang, J., Liu, Z., Li, Y., Asif Ali, M., Xu, M., Ahluwalia, T. S. I., Boer, J. M. A., Chen, P., Daimon, M., & 89 othersEriksson, J., Perola, M., Friedlander, Y., Gao, Y. T., Heppe, D. H. M., Holloway, J. W., Houston, D. K., Kanoni, S., Kim, Y. M., Laaksonen, M. A., Jääskeläinen, T., Lee, N. R., Lehtimäki, T., Lemaitre, R. N., Lu, W., Luben, R. N., Manichaikul, A., Männistö, S., Marques-Vidal, P., Monda, K. L., Ngwa, J. S., Perusse, L., van Rooij, F. J. A., Xiang, Y. B., Wen, W., Wojczynski, M. K., Zhu, J., Borecki, I. B., Bouchard, C., Cai, Q., Cooper, C., Dedoussis, G. V., Deloukas, P., Ferrucci, L., Forouhi, N. G., Hansen, T., Christiansen, L., Hofman, A., Johansson, I., Jørgensen, T., Karasawa, S., Khaw, K. T., Kim, M. K., Kristiansson, K., Li, H., Lin, X., Liu, Y., Lohman, K. K., Long, J., Mikkilä, V., Mozaffarian, D., North, K., Pedersen, O., Raitakari, O., Rissanen, H., Tuomilehto, J., van der Schouw, Y. T., Uitterlinden, A. G., Zillikens, M. C., Franco, O. H., Shyong Tai, E., Ou Shu, X., Siscovick, D. S., Toft, U., Verschuren, W. M. M., Vollenweider, P., Wareham, N. J., Witteman, J. C. M., Zheng, W., Ridker, P. M., Kang, J. H., Liang, L., Jensen, M. K., Curhan, G. C., Pasquale, L. R., Hunter, D. J., Mohlke, K. L., Uusitupa, M., Cupples, L. A., Rankinen, T., Orho-Melander, M., Wang, T., Chasman, D. I., Franks, P. W., Sørensen, T. I. A., Hu, F. B., Loos, R. J. F., Nettleton, J. A. & Qi, L., Dec 20 2014, In: Human molecular genetics. 23, 25, p. 6961-6972 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    133 Scopus citations

  • Generation and purification of highly specific antibodies for detecting post-translationally modified proteins in vivo

    Arur, S. & Schedl, T., Feb 2014, In: Nature Protocols. 9, 2, p. 375-395 21 p.

    Research output: Contribution to journal › Article › peer-review

    16 Scopus citations

  • Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol

    Feitosa, M. F., Wojczynski, M. K., Straka, R., Kammerer, C. M., Lee, J. H., Kraja, A. T., Christensen, K., Newman, A. B., Province, M. A. & Borecki, I. B., 2014, In: Frontiers in Genetics. 5, JUN, Article 159.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Scopus citations

  • Genetic risk scores associated with baseline lipoprotein subfraction concentrations do not associate with their responses to fenofibrate

    Frazier-Wood, A. C., Wojczynski, M. K., Borecki, I. B., Hopkins, P. N., Lai, C. Q., Ordovas, J. M., Straka, R. J., Tsai, M. Y., Tiwari, H. K. & Arnett, D. K., Aug 25 2014, In: Biology. 3, 3, p. 536-550 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease

    COPDGene and ECLIPSE Investigators, Sep 21 2014, In: Respiratory Research. 15, 1, 113.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    46 Scopus citations

  • Genetic variants associated with lung function: The long life family study

    Thyagarajan, B., Wojczynski, M., Minster, R. L., Sanders, J., Barral, S., Christiansen, L., Barr, R. G. & Newman, A., Nov 1 2014, In: Respiratory Research. 15, 1, 134.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • Genome-wide association analysis identifies six new loci associated with forced vital capacity

    Loth, D. W., Artigas, M. S., Gharib, S. A., Wain, L. V., Franceschini, N., Koch, B., Pottinger, T. D., Smith, A. V., Duan, Q., Oldmeadow, C., Lee, M. K., Strachan, D. P., James, A. L., Huffman, J. E., Vitart, V., Ramasamy, A., Wareham, N. J., Kaprio, J., Wang, X. Q., Trochet, H., & 140 othersKähönen, M., Flexeder, C., Albrecht, E., Lopez, L. M., De Jong, K., Thyagarajan, B., Alves, A. C., Enroth, S., Omenaas, E., Joshi, P. K., Fall, T., Viñuela, A., Launer, L. J., Loehr, L. R., Fornage, M., Li, G., Wilk, J. B., Tang, W., Manichaikul, A., Lahousse, L., Harris, T. B., North, K. E., Rudnicka, A. R., Hui, J., Gu, X., Lumley, T., Wright, A. F., Hastie, N. D., Campbell, S., Kumar, R., Pin, I., Scott, R. A., Pietiläinen, K. H., Surakka, I., Liu, Y., Holliday, E. G., Schulz, H., Heinrich, J., Davies, G., Vonk, J. M., Wojczynski, M., Pouta, A., Johansson, A., Wild, S. H., Ingelsson, E., Rivadeneira, F., Völzke, H., Hysi, P. G., Eiriksdottir, G., Morrison, A. C., Rotter, J. I., Gao, W., Postma, D. S., White, W. B., Rich, S. S., Hofman, A., Aspelund, T., Couper, D., Smith, L. J., Psaty, B. M., Lohman, K., Burchard, E. G., Uitterlinden, A. G., Garcia, M., Joubert, B. R., McArdle, W. L., Musk, A. B., Hansel, N., Heckbert, S. R., Zgaga, L., Van Meurs, J. B. J., Navarro, P., Rudan, I., Oh, Y. M., Redline, S., Jarvis, D. L., Zhao, J. H., Rantanen, T., O'Connor, G. T., Ripatti, S., Scott, R. J., Karrasch, S., Grallert, H., Gaddis, N. C., Starr, J. M., Wijmenga, C., Minster, R. L., Lederer, D. J., Pekkanen, J., Gyllensten, U., Campbell, H., Morris, A. P., Gläser, S., Hammond, C. J., Burkart, K. M., Beilby, J., Kritchevsky, S. B., Gudnason, V., Hancock, D. B., Williams, O. D., Polasek, O., Zemunik, T., Kolcic, I., Petrini, M. F., Wjst, M., Kim, W. J., Porteous, D. J., Scotland, G., Smith, B. H., Viljanen, A., Heliövaara, M., Attia, J. R., Sayers, I., Hampel, R., Gieger, C., Deary, I. J., Boezen, H. M., Newman, A., Jarvelin, M. R., Wilson, J. F., Lind, L., Stricker, B. H., Teumer, A., Spector, T. D., Melén, E., Peters, M. J., Lange, L. A., Barr, R. G., Bracke, K. R., Verhamme, F. M., Sung, J., Hiemstra, P. S., Cassano, P. A., Sood, A., Hayward, C., Dupuis, J., Hall, I. P., Brusselle, G. G., Tobin, M. D. & London, S. J., Jul 2014, In: Nature Genetics. 46, 7, p. 669-677 9 p.

    Research output: Contribution to journal › Article › peer-review

    108 Scopus citations

  • Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response

    An, P., Straka, R. J., Pollin, T. I., Feitosa, M. F., Wojczynski, M. K., Daw, E. W., O'Connell, J. R., Gibson, Q., Ryan, K. A., Hopkins, P. N., Tsai, M. Y., Lai, C. Q., Province, M. A., Ordovas, J. M., Shuldiner, A. R., Arnett, D. K. & Borecki, I. B., Jul 2014, In: Human genetics. 133, 7, p. 919-930 12 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations

  • Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: The Long Life Family Study (LLFS)

    An, P., Miljkovic, I., Thyagarajan, B., Kraja, A. T., Daw, E. W., Pankow, J. S., Selvin, E., Kao, W. H. L., Maruthur, N. M., Nalls, M. A., Liu, Y., Harris, T. B., Lee, J. H., Borecki, I. B., Christensen, K., Eckfeldt, J. H., Mayeux, R., Perls, T. T., Newman, A. B. & Province, M. A., Apr 2014, In: Metabolism: clinical and experimental. 63, 4, p. 461-468 8 p.

    Research output: Contribution to journal › Article › peer-review

    19 Scopus citations

  • Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of Nitric oxide synthase and Fd59a/Fox-D

    Lacin, H., Rusch, J., Yeh, R. T., Fujioka, M., Wilson, B. A., Zhu, Y., Robie, A. A., Mistry, H., Wang, T., Jaynes, J. B. & Skeath, J. B., Apr 1 2014, In: Developmental Biology. 388, 1, p. 117-133 17 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    23 Scopus citations

  • High-resolution specificity from DNA sequencing highlights alternative modes of lac repressor binding

    Zuo, Z. & Stormo, G. D., Nov 1 2014, In: Genetics. 198, 3, p. 1329-1343 15 p.

    Research output: Contribution to journal › Article › peer-review

    33 Scopus citations