Search results

  • Article

    Genome- and CD4+ T-cell methylome-wide association study of circulating trimethylamine-N-oxide in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN)

    Aslibekyan, S., Irvin, M. R., Hidalgo, B. A., Perry, R. T., Jeyarajah, E. J., Garcia, E., Shalaurova, I., Hopkins, P. N., Province, M. A., Tiwari, H. K., Ordovas, J. M., Absher, D. M. & Arnett, D. K., Jun 1 2017, In: Journal of Nutrition and Intermediary Metabolism. 8, p. 1-7 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • Genome scan for quantitative trait loci linked to high-density lipoprotein cholesterol: The NHLBI Family Heart Study

    Peacock, J. M., Arnett, D. K., Atwood, L. D., Myers, R. H., Coon, H., Rich, S. S., Province, M. A. & Heiss, G., 2001, In: Arteriosclerosis, thrombosis, and vascular biology. 21, 11, p. 1823-1828 6 p.

    Research output: Contribution to journalArticlepeer-review

    56 Scopus citations
  • Genome scans for blood pressure and hypertension: The National Heart, Lung, and Blood Institute Family Heart Study

    Hunt, S. C., Ellison, R. C., Atwood, L. D., Pankow, J. S., Province, M. A. & Leppert, M. F., 2002, In: Hypertension. 40, 1, p. 1-6 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    94 Scopus citations
  • Genome screen for platelet monoamine oxidase (MAO) activity

    Saccone, N. L., Rice, J. P., Rochberg, N., Goate, A., Reich, T., Shears, S., Wu, W., Nurnberger, J. I., Foroud, T., Edenberg, H. J. & Li, T. K., Oct 15 1999, In: American Journal of Medical Genetics - Neuropsychiatric Genetics. 88, 5, p. 517-521 5 p.

    Research output: Contribution to journalArticlepeer-review

    13 Scopus citations
  • Genome sequencing identifies multiple deleterious variants in autism patients with more severe phenotypes

    University of Washington Center for Mendelian Genomics, Jul 1 2019, In: Genetics in Medicine. 21, 7, p. 1611-1620 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    80 Scopus citations
  • Genome Sequencing of Autism-Affected Families Reveals Disruption of Putative Noncoding Regulatory DNA

    Turner, T. N., Hormozdiari, F., Duyzend, M. H., McClymont, S. A., Hook, P. W., Iossifov, I., Raja, A., Baker, C., Hoekzema, K., Stessman, H. A., Zody, M. C., Nelson, B. J., Huddleston, J., Sandstrom, R., Smith, J. D., Hanna, D., Swanson, J. M., Faustman, E. M., Bamshad, M. J., Stamatoyannopoulos, J., & 4 othersNickerson, D. A., McCallion, A. S., Darnell, R. & Eichler, E. E., Jan 7 2016, In: American journal of human genetics. 98, 1, p. 58-74 17 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    193 Scopus citations
  • Genome sequencing reveals novel noncoding variants in PLA2G6 and LMNB1 causing progressive neurologic disease

    Undiagnosed Disease Network, Apr 1 2022, In: Molecular Genetics and Genomic Medicine. 10, 4, e1892.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Genome sequencing unveils a regulatory landscape of platelet reactivity

    NHLBI Trans-Omics for Precision (TOPMed) Consortium, Dec 1 2021, In: Nature communications. 12, 1, 3626.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    28 Scopus citations
  • Genome-wide admixture mapping for coronary artery calcification in African Americans: The NHLBI family heart study

    Zhang, Q., Lewis, C. E., Wagenknecht, L. E., Myers, R. H., Pankow, J. S., Hunt, S. C., North, K. E., Hixson, J. E., Carr, J. J., Shimmin, L. C., Borecki, I. & Province, M. A., Apr 2008, In: Genetic Epidemiology. 32, 3, p. 264-272 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • Genomewide analysis of inherited variation associated with phosphorylation of PI3K/AKT/mTOR signaling proteins

    Hutz, J. E., Manning, W. A., Province, M. A. & McLeod, H. L., Sep 19 2011, In: PloS one. 6, 9, e24873.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation

    Longchamps, R. J., Yang, S. Y., Castellani, C. A., Shi, W., Lane, J., Grove, M. L., Bartz, T. M., Sarnowski, C., Liu, C., Burrows, K., Guyatt, A. L., Gaunt, T. R., Kacprowski, T., Yang, J., De Jager, P. L., Yu, L., Bergman, A., Xia, R., Fornage, M., Feitosa, M. F., & 32 othersWojczynski, M. K., Kraja, A. T., Province, M. A., Amin, N., Rivadeneira, F., Tiemeier, H., Uitterlinden, A. G., Broer, L., Van Meurs, J. B. J., Van Duijn, C. M., Raffield, L. M., Lange, L., Rich, S. S., Lemaitre, R. N., Goodarzi, M. O., Sitlani, C. M., Mak, A. C. Y., Bennett, D. A., Rodriguez, S., Murabito, J. M., Lunetta, K. L., Sotoodehnia, N., Atzmon, G., Ye, K., Barzilai, N., Brody, J. A., Psaty, B. M., Taylor, K. D., Rotter, J. I., Boerwinkle, E., Pankratz, N. & Arking, D. E., Jan 2022, In: Human genetics. 141, 1, p. 127-146 20 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • Genome-wide and candidate gene association study of cigarette smoking behaviors

    Caporaso, N., Gu, F., Chatterjee, N., Sheng-Chih, J., Yu, K., Yeager, M., Chen, C., Jacobs, K., Wheeler, W., Landi, M. T., Ziegler, R. G., Hunter, D. J., Chanock, S., Hankinson, S., Kraft, P. & Bergen, A. W., 2009, In: PloS one. 4, 2, e4653.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    209 Scopus citations
  • Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

    23and Me Research Team, eQTLgen Consortium, International Cannabis Consortium & Social Science Genetic Association Consortium, Feb 1 2019, In: Nature Genetics. 51, 2, p. 245-257 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    364 Scopus citations
  • Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH

    MAGIC Investigators, Diabetes Prevention Program (DPP) Research Group, Province, M. A., White, N. H. & Brown, A. L., Jul 2023, In: Diabetologia. 66, 7, p. 1260-1272 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Genome-wide association analysis identifies six new loci associated with forced vital capacity

    Loth, D. W., Artigas, M. S., Gharib, S. A., Wain, L. V., Franceschini, N., Koch, B., Pottinger, T. D., Smith, A. V., Duan, Q., Oldmeadow, C., Lee, M. K., Strachan, D. P., James, A. L., Huffman, J. E., Vitart, V., Ramasamy, A., Wareham, N. J., Kaprio, J., Wang, X. Q., Trochet, H., & 140 othersKähönen, M., Flexeder, C., Albrecht, E., Lopez, L. M., De Jong, K., Thyagarajan, B., Alves, A. C., Enroth, S., Omenaas, E., Joshi, P. K., Fall, T., Viñuela, A., Launer, L. J., Loehr, L. R., Fornage, M., Li, G., Wilk, J. B., Tang, W., Manichaikul, A., Lahousse, L., Harris, T. B., North, K. E., Rudnicka, A. R., Hui, J., Gu, X., Lumley, T., Wright, A. F., Hastie, N. D., Campbell, S., Kumar, R., Pin, I., Scott, R. A., Pietiläinen, K. H., Surakka, I., Liu, Y., Holliday, E. G., Schulz, H., Heinrich, J., Davies, G., Vonk, J. M., Wojczynski, M., Pouta, A., Johansson, A., Wild, S. H., Ingelsson, E., Rivadeneira, F., Völzke, H., Hysi, P. G., Eiriksdottir, G., Morrison, A. C., Rotter, J. I., Gao, W., Postma, D. S., White, W. B., Rich, S. S., Hofman, A., Aspelund, T., Couper, D., Smith, L. J., Psaty, B. M., Lohman, K., Burchard, E. G., Uitterlinden, A. G., Garcia, M., Joubert, B. R., McArdle, W. L., Musk, A. B., Hansel, N., Heckbert, S. R., Zgaga, L., Van Meurs, J. B. J., Navarro, P., Rudan, I., Oh, Y. M., Redline, S., Jarvis, D. L., Zhao, J. H., Rantanen, T., O'Connor, G. T., Ripatti, S., Scott, R. J., Karrasch, S., Grallert, H., Gaddis, N. C., Starr, J. M., Wijmenga, C., Minster, R. L., Lederer, D. J., Pekkanen, J., Gyllensten, U., Campbell, H., Morris, A. P., Gläser, S., Hammond, C. J., Burkart, K. M., Beilby, J., Kritchevsky, S. B., Gudnason, V., Hancock, D. B., Williams, O. D., Polasek, O., Zemunik, T., Kolcic, I., Petrini, M. F., Wjst, M., Kim, W. J., Porteous, D. J., Scotland, G., Smith, B. H., Viljanen, A., Heliövaara, M., Attia, J. R., Sayers, I., Hampel, R., Gieger, C., Deary, I. J., Boezen, H. M., Newman, A., Jarvelin, M. R., Wilson, J. F., Lind, L., Stricker, B. H., Teumer, A., Spector, T. D., Melén, E., Peters, M. J., Lange, L. A., Barr, R. G., Bracke, K. R., Verhamme, F. M., Sung, J., Hiemstra, P. S., Cassano, P. A., Sood, A., Hayward, C., Dupuis, J., Hall, I. P., Brusselle, G. G., Tobin, M. D. & London, S. J., Jul 2014, In: Nature Genetics. 46, 7, p. 669-677 9 p.

    Research output: Contribution to journalArticlepeer-review

    110 Scopus citations
  • Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

    GIANT Consortium, Global BPgen Consortium, NASH CRN, GIANT Consortium, MAGIC Investigators, GOLD Consortium, MAGIC, on behalf of Procardis Consortium & DIAGRAM Consortium, Mar 1 2011, In: PLoS genetics. 7, 3, e1001324.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    783 Scopus citations
  • Genome-wide association and functional follow-up reveals new loci for kidney function

    Pattaro, C., Köttgen, A., Teumer, A., Garnaas, M., Böger, C. A., Fuchsberger, C., Olden, M., Chen, M. H., Tin, A., Taliun, D., Li, M., Gao, X., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C., O'Seaghdha, C. M., Glazer, N., Isaacs, A., Liu, C. T., & 146 othersSmith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Johnson, A. D., Gierman, H. J., Feitosa, M., Hwang, S. J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, Å., Tönjes, A., Dehghan, A., Chouraki, V., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimäki, T., Esko, T., Deshmukh, H., Ulivi, S., Chu, A. Y., Murgia, F., Trompet, S., Imboden, M., Kollerits, B., Pistis, G., Harris, T. B., Launer, L. J., Aspelund, T., Eiriksdottir, G., Mitchell, B. D., Boerwinkle, E., Schmidt, H., Cavalieri, M., Rao, M., Hu, F. B., Demirkan, A., Oostra, B. A., de Andrade, M., Turner, S. T., Ding, J., Andrews, J. S., Freedman, B. I., Koenig, W., Illig, T., Döring, A., Wichmann, H. E., Kolcic, I., Zemunik, T., Boban, M., Minelli, C., Wheeler, H. E., Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Nöthlings, U., Jacobs, G., Biffar, R., Endlich, K., Ernst, F., Homuth, G., Kroemer, H. K., Nauck, M., Stracke, S., Völker, U., Völzke, H., Kovacs, P., Stumvoll, M., Mägi, R., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Aulchenko, Y. S., Polasek, O., Hastie, N., Vitart, V., Helmer, C., Wang, J. J., Ruggiero, D., Bergmann, S., Kähönen, M., Viikari, J., Nikopensius, T., Province, M., Ketkar, S., Colhoun, H., Doney, A., Robino, A., Giulianini, F., Krämer, B. K., Portas, L., Ford, I., Buckley, B. M., Adam, M., Thun, G. A., Paulweber, B., Haun, M., Sala, C., Metzger, M., Mitchell, P., Ciullo, M., Kim, S. K., Vollenweider, P., Raitakari, O., Metspalu, A., Palmer, C., Gasparini, P., Pirastu, M., Jukema, J. W., Probst-Hensch, N. M., Kronenberg, F., Toniolo, D., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Ferrucci, L., Siscovick, D. S., van Duijn, C. M., Borecki, I., Kardia, S. L. R., Liu, Y., Curhan, G. C., Rudan, I., Gyllensten, U., Wilson, J. F., Franke, A., Pramstaller, P. P., Rettig, R., Prokopenko, I., Witteman, J. C. M., Hayward, C., Ridker, P., Parsa, A., Bochud, M., Heid, I. M., Goessling, W., Chasman, D. I., Kao, W. H. L. & Fox, C. S., Mar 2012, In: PLoS genetics. 8, 3, e1002584.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    155 Scopus citations
  • Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: The long life family study

    Lee, J. H., Cheng, R., Honig, L. S., Feitosa, M., Kammerer, C. M., Kang, M. S., Schupf, N., Lin, S. J., Sanders, J. L., Bae, H., Druley, T., Perls, T., Christensen, K., Province, M. & Mayeux, R., 2013, In: Frontiers in Genetics. 4, JAN, Article 310.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    56 Scopus citations
  • Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology

    Levy, D., Neuhausen, S. L., Hunt, S. C., Kimura, M., Hwang, S. J., Chen, W., Bis, J. C., Fitzpatrick, A. L., Smith, E., Johnson, A. D., Gardner, J. P., Srinivasan, S. R., Schork, N., Rotter, J. I., Herbig, U., Psaty, B. M., Sastrasinh, M., Murray, S. S., Vasan, R. S., Province, M. A., & 9 othersGlazer, N. L., Lu, X., Cao, X., Kronmal, R., Mangino, M., Soranzo, N., Spector, T. D., Berenson, G. S. & Aviv, A., May 18 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 20, p. 9293-9298 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    228 Scopus citations
  • Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease

    Chen, Y., Du, X., Kuppa, A., Feitosa, M. F., Bielak, L. F., O’Connell, J. R., Musani, S. K., Guo, X., Kahali, B., Chen, V. L., Smith, A. V., Ryan, K. A., Eirksdottir, G., Allison, M. A., Bowden, D. W., Budoff, M. J., Carr, J. J., Chen, Y. D. I., Taylor, K. D., Oliveri, A., & 17 othersCorrea, A., Crudup, B. F., Kardia, S. L. R., Mosley, T. H., Norris, J. M., Terry, J. G., Rotter, J. I., Wagenknecht, L. E., Halligan, B. D., Young, K. A., Hokanson, J. E., Washko, G. R., Gudnason, V., Province, M. A., Peyser, P. A., Palmer, N. D. & Speliotes, E. K., Oct 2023, In: Nature Genetics. 55, 10, p. 1640-1650 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    20 Scopus citations
  • Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts

    Mozaffarian, D., Dashti, H. S., Wojczynski, M. K., Chu, A. Y., Nettleton, J. A., Männistö, S., Kristiansson, K., Reedik, M., Lahti, J., Houston, D. K., Cornelis, M. C., Van Rooij, F. J. A., Dimitriou, M., Kanoni, S., Mikkilä, V., Steffen, L. M., De Oliveira Otto, M. C., Qi, L., Psaty, B., Djousse, L., & 45 othersRotter, J. I., Harald, K., Perola, M., Rissanen, H., Jula, A., Krista, F., Mihailov, E., Feitosa, M. F., Ngwa, J. S., Xue, L., Jacques, P. F., Perälä, M. M., Palotie, A., Liu, Y., Nalls, N. A., Ferrucci, L., Hernandez, D., Manichaikul, A., Tsai, M. Y., Kiefte-De Jong, J. C., Hofman, A., Uitterlinden, A. G., Rallidis, L., Ridker, P. M., Rose, L. M., Buring, J. E., Lehtimäki, T., Kähönen, M., Viikari, J., Lemaitre, R., Salomaa, V., Knekt, P., Metspalu, A., Borecki, I. B., Cupples, L. A., Eriksson, J. G., Kritchevsky, S. B., Bandinelli, S., Siscovick, D., Franco, O. H., Deloukas, P., Dedoussis, G., Chasman, D. I., Raitakari, O. & Tanaka, T., Dec 2017, In: PloS one. 12, 12, e0186456.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci

    Liu, C. T., Monda, K. L., Taylor, K. C., Lange, L., Demerath, E. W., Palmas, W., Wojczynski, M. K., Ellis, J. C., Vitolins, M. Z., Liu, S., Papanicolaou, G. J., Irvin, M. R., Xue, L., Griffin, P. J., Nalls, M. A., Adeyemo, A., Liu, J., Li, G., Ruiz-Narvaez, E. A., Chen, W. M., & 73 othersChen, F., Henderson, B. E., Millikan, R. C., Ambrosone, C. B., Strom, S. S., Guo, X., Andrews, J. S., Sun, Y. V., Mosley, T. H., Yanek, L. R., Shriner, D., Haritunians, T., Rotter, J. I., Speliotes, E. K., Smith, M., Rosenberg, L., Mychaleckyj, J., Nayak, U., Spruill, I., Garvey, W. T., Pettaway, C., Nyante, S., Bandera, E. V., Britton, A. F., Zonderman, A. B., Rasmussen-Torvik, L. J., Chen, Y. D. I., Ding, J., Lohman, K., Kritchevsky, S. B., Zhao, W., Peyser, P. A., Kardia, S. L. R., Kabagambe, E., Broeckel, U., Chen, G., Zhou, J., Wassertheil-Smoller, S., Neuhouser, M. L., Rampersaud, E., Psaty, B., Kooperberg, C., Manson, J. A. E., Kuller, L. H., Ochs-Balcom, H. M., Johnson, K. C., Sucheston, L., Ordovas, J. M., Palmer, J. R., Haiman, C. A., McKnight, B., Howard, B. V., Becker, D. M., Bielak, L. F., Liu, Y., Allison, M. A., Grant, S. F. A., Burke, G. L., Patel, S. R., Schreiner, P. J., Borecki, I. B., Evans, M. K., Taylor, H., Sale, M. M., Howard, V., Carlson, C. S., Rotimi, C. N., Cushman, M., Harris, T. B., Reiner, A. P., Cupples, L. A., North, K. E. & Fox, C. S., Aug 2013, In: PLoS genetics. 9, 8, e1003681.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    105 Scopus citations
  • Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response

    An, P., Straka, R. J., Pollin, T. I., Feitosa, M. F., Wojczynski, M. K., Daw, E. W., O'Connell, J. R., Gibson, Q., Ryan, K. A., Hopkins, P. N., Tsai, M. Y., Lai, C. Q., Province, M. A., Ordovas, J. M., Shuldiner, A. R., Arnett, D. K. & Borecki, I. B., Jul 2014, In: Human genetics. 133, 7, p. 919-930 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    10 Scopus citations
  • Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

    Wilk, J. B., Shrine, N. R. G., Loehr, L. R., Zhao, J. H., Manichaikul, A., Lopez, L. M., Smith, A. V., Heckbert, S. R., Smolonska, J., Tang, W., Loth, D. W., Curjuric, I., Hui, J., Cho, M. H., Latourelle, J. C., Henry, A. P., Aldrich, M., Bakke, P., Beaty, T. H., Bentley, A. R., & 59 othersBorecki, I. B., Brusselle, G. G., Burkart, K. M., Chen, T. H., Couper, D., Crapo, J. D., Davies, G., Dupuis, J., Franceschini, N., Gulsvik, A., Hancock, D. B., Harris, T. B., Hofman, A., Imboden, M., James, A. L., Khaw, K. T., Lahousse, L., Launer, L. J., Litonjua, A., Liu, Y., Lohman, K. K., Lomas, D. A., Lumley, T., Marciante, K. D., McArdle, W. L., Meibohm, B., Morrison, A. C., Musk, A. W., Myers, R. H., North, K. E., Postma, D. S., Psaty, B. M., Rich, S. S., Rivadeneira, F., Rochat, T., Rotter, J. I., Soler Artigas, M., Starr, J. M., Uitterlinden, A. G., Wareham, N. J., Wijmenga, C., Zanen, P., Province, M. A., Silverman, E. K., Deary, I. J., Palmer, L. J., Cassano, P. A., Gudnason, V., Barr, R. G., Loos, R. J. F., Strachan, D. P., London, S. J., Boezen, H. M., Probst-Hensch, N., Gharib, S. A., Hall, I. P., O'Connor, G. T., Tobin, M. D. & Stricker, B. H., Oct 1 2012, In: American journal of respiratory and critical care medicine. 186, 7, p. 622-632 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    152 Scopus citations
  • Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence

    Hancock, D. B., Guo, Y., Reginsson, G. W., Gaddis, N. C., Lutz, S. M., Sherva, R., Loukola, A., Minica, C. C., Markunas, C. A., Han, Y., Young, K. A., Gudbjartsson, D. F., Gu, F., McNeil, D. W., Qaiser, B., Glasheen, C., Olson, S., Landi, M. T., Madden, P. A. F., Farrer, L. A., & 18 othersVink, J., Saccone, N. L., Neale, M. C., Kranzler, H. R., McKay, J., Hung, R. J., Amos, C. I., Marazita, M. L., Boomsma, D. I., Baker, T. B., Gelernter, J., Kaprio, J., Caporaso, N. E., Thorgeirsson, T. E., Hokanson, J. E., Bierut, L. J., Stefansson, K. & Johnson, E. O., Sep 1 2018, In: Molecular Psychiatry. 23, 9, p. 1911-1919 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    62 Scopus citations
  • Genome-wide association study and linkage analysis of the healthy aging index

    Minster, R. L., Sanders, J. L., Singh, J., Kammerer, C. M., Barmada, M. M., Matteini, A. M., Zhang, Q., Wojczynski, M. K., Daw, E. W., Brody, J. A., Arnold, A. M., Lunetta, K. L., Murabito, J. M., Christensen, K., Perls, T. T., Province, M. A. & Newman, A. B., Aug 2015, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 70, 8, p. 1003-1008 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    15 Scopus citations
  • Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction

    Odonnell, C. J., Kavousi, M., Smith, A. V., Kardia, S. L. R., Feitosa, M. F., Hwang, S. J., Sun, Y. V., Province, M. A., Aspelund, T., Dehghan, A., Hoffmann, U., Bielak, L. F., Zhang, Q., Eiriksdottir, G., Van Duijn, C. M., Fox, C. S., De Andrade, M., Kraja, A. T., Sigurdsson, S., Elias-Smale, S. E., & 47 othersMurabito, J. M., Launer, L. J., Van Der Lugt, A., Kathiresan, S., Krestin, G. P., Herrington, D. M., Howard, T. D., Liu, Y., Post, W., Mitchell, B. D., Oconnell, J. R., Shen, H., Shuldiner, A. R., Altshuler, D., Elosua, R., Salomaa, V., Schwartz, S. M., Siscovick, D. S., Voight, B. F., Bis, J. C., Glazer, N. L., Psaty, B. M., Boerwinkle, E., Heiss, G., Blankenberg, S., Zeller, T., Wild, P. S., Schnabel, R. B., Schillert, A., Ziegler, A., Münzel, T. F., White, C. C., Rotter, J. I., Nalls, M., Oudkerk, M., Johnson, A. D., Newman, A. B., Uitterlinden, A. G., Massaro, J. M., Cunningham, J., Harris, T. B., Hofman, A., Peyser, P. A., Borecki, I. B., Cupples, L. A., Gudnason, V. & Witteman, J. C. M., Dec 20 2011, In: Circulation. 124, 25, p. 2855-2864 10 p.

    Research output: Contribution to journalArticlepeer-review

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    248 Scopus citations
  • Genome-wide association study identifies 74 loci associated with educational attainment

    Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G. B., Emilsson, V., Meddens, S. F. W., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P., De Vlaming, R., Abdellaoui, A., Ahluwalia, T. S., Bacelis, J., Baumbach, C., Bjornsdottir, G., & 235 othersBrandsma, J. H., Pina Concas, M., Derringer, J., Furlotte, N. A., Galesloot, T. E., Girotto, G., Gupta, R., Hall, L. M., Harris, S. E., Hofer, E., Horikoshi, M., Huffman, J. E., Kaasik, K., Kalafati, I. P., Karlsson, R., Kong, A., Lahti, J., Van Der Lee, S. J., Deleeuw, C., Lind, P. A., Lindgren, K. O., Liu, T., Mangino, M., Marten, J., Mihailov, E., Miller, M. B., Van Der Most, P. J., Oldmeadow, C., Payton, A., Pervjakova, N., Peyrot, W. J., Qian, Y., Raitakari, O., Rueedi, R., Salvi, E., Schmidt, B., Schraut, K. E., Shi, J., Smith, A. V., Poot, R. A., St Pourcain, B., Teumer, A., Thorleifsson, G., Verweij, N., Vuckovic, D., Wellmann, J., Westra, H. J., Yang, J., Zhao, W., Zhu, Z., Alizadeh, B. Z., Amin, N., Bakshi, A., Baumeister, S. E., Biino, G., Bønnelykke, K., Boyle, P. A., Campbell, H., Cappuccio, F. P., Davies, G., De Neve, J. E., Deloukas, P., Demuth, I., Ding, J., Eibich, P., Eisele, L., Eklund, N., Evans, D. M., Faul, J. D., Feitosa, M. F., Forstner, A. J., Gandin, I., Gunnarsson, B., Halldórsson, B. V., Harris, T. B., Holliday, E. G., Heath, A. C., Hocking, L. J., Homuth, G., Horan, M. A., Hottenga, J. J., De Jager, P. L., Joshi, P. K., Jugessur, A., Kaakinen, M. A., Kähönen, M., Kanoni, S., Keltigangas-Järvinen, L., Kiemeney, L. A. L. M., Kolcic, I., Koskinen, S., Kraja, A. T., Kroh, M., Kutalik, Z., Latvala, A., Launer, L. J., Lebreton, M. P., Levinson, D. F., Lichtenstein, P., Lichtner, P., Liewald, D. C. M., Loukola, A., Madden, P. A., Mägi, R., Mäki-Opas, T., Marioni, R. E., Marques-Vidal, P., Meddens, G. A., Mcmahon, G., Meisinger, C., Meitinger, T., Milaneschi, Y., Milani, L., Montgomery, G. W., Myhre, R., Nelson, C. P., Nyholt, D. R., Ollier, W. E. R., Palotie, A., Paternoster, L., Pedersen, N. L., Petrovic, K. E., Porteous, D. J., Raïkkönen, K., Ring, S. M., Robino, A., Rostapshova, O., Rudan, I., Rustichini, A., Salomaa, V., Sanders, A. R., Sarin, A. P., Schmidt, H., Scott, R. J., Smith, B. H., Smith, J. A., Staessen, J. A., Steinhagen-Thiessen, E., Strauch, K., Terracciano, A., Tobin, M. D., Ulivi, S., Vaccargiu, S., Quaye, L., Van Rooij, F. J. A., Venturini, C., Vinkhuyzen, A. A. E., Völker, U., Völzke, H., Vonk, J. M., Vozzi, D., Waage, J., Ware, E. B., Willemsen, G., Attia, J. R., Bennett, D. A., Berger, K., Bertram, L., Bisgaard, H., Boomsma, D. I., Borecki, I. B., Bültmann, U., Chabris, C. F., Cucca, F., Cusi, D., Deary, I. J., Dedoussis, G. V., Van Duijn, C. M., Eriksson, J. G., Franke, B., Franke, L., Gasparini, P., Gejman, P. V., Gieger, C., Grabe, H. J., Gratten, J., Groenen, P. J. F., Gudnason, V., Van Der Harst, P., Hayward, C., Hinds, D. A., Hoffmann, W., Hyppönen, E., Iacono, W. G., Jacobsson, B., Järvelin, M. R., Jöckel, K. H., Kaprio, J., Kardia, S. L. R., Lehtimäki, T., Lehrer, S. F., Magnusson, P. K. E., Martin, N. G., Mcgue, M., Metspalu, A., Pendleton, N., Penninx, B. W. J. H., Perola, M., Pirastu, N., Pirastu, M., Polasek, O., Posthuma, D., Power, C., Province, M. A., Samani, N. J., Schlessinger, D., Schmidt, R., Sørensen, T. I. A., Spector, T. D., Stefansson, K., Thorsteinsdottir, U., Thurik, A. R., Timpson, N. J., Tiemeier, H., Tung, J. Y., Uitterlinden, A. G., Vitart, V., Vollenweider, P., Weir, D. R., Wilson, J. F., Wright, A. F., Conley, D. C., Krueger, R. F., Davey Smith, G., Hofman, A., Laibson, D. I., Medland, S. E., Meyer, M. N., Yang, J., Johannesson, M., Visscher, P. M., Esko, T., Koellinger, P. D., Cesarini, D. & Benjamin, D. J., May 11 2016, In: Nature. 533, 7604, p. 539-542 4 p.

    Research output: Contribution to journalArticlepeer-review

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    806 Scopus citations
  • Genome-wide association study identifies a novel locus for cannabis dependence

    Agrawal, A., Chou, Y. L., Carey, C. E., Baranger, D. A. A., Zhang, B., Sherva, R., Wetherill, L., Kapoor, M., Wang, J. C., Bertelsen, S., Anokhin, A. P., Hesselbrock, V., Kramer, J., Lynskey, M. T., Meyers, J. L., Nurnberger, J. I., Rice, J. P., Tischfield, J., Bierut, L. J., Degenhardt, L., & 16 othersFarrer, L. A., Gelernter, J., Hariri, A. R., Heath, A. C., Kranzler, H. R., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Porjesz, B., Wang, T., Whitfield, J. B., Edenberg, H. J., Foroud, T., Goate, A. M., Bogdan, R. & Nelson, E. C., May 1 2018, In: Molecular Psychiatry. 23, 5, p. 1293-1302 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    31 Scopus citations
  • Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: The Long Life Family Study (LLFS)

    An, P., Miljkovic, I., Thyagarajan, B., Kraja, A. T., Daw, E. W., Pankow, J. S., Selvin, E., Kao, W. H. L., Maruthur, N. M., Nalls, M. A., Liu, Y., Harris, T. B., Lee, J. H., Borecki, I. B., Christensen, K., Eckfeldt, J. H., Mayeux, R., Perls, T. T., Newman, A. B. & Province, M. A., Apr 2014, In: Metabolism: clinical and experimental. 63, 4, p. 461-468 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    19 Scopus citations
  • Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

    Alcohol Genome-wide Association (AlcGen) Consortium; Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study; Genetic Investigation of Anthropometric Traits (GIANT) Consortium; Global Lipids Genetics Consortium; Genetics of Liver Disease (GOLD) Consortium; International Consortium for Blood Pressure (ICBP-GWAS); Meta-analyses of Glucose and Insulin-Related Traits Consortium (MAGIC) & Collaborators, Nov 1 2011, In: Nature Genetics. 43, 11, p. 1131-1138 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    439 Scopus citations
  • Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

    Lifelines Cohort Study, EchoGen consortium, AortaGen Consortium, CHARGE Consortium Heart Failure Working Group, KidneyGen Consortium & CKDGen consortium; Cardiogenics consortium; CardioGram, Oct 1 2011, In: Nature Genetics. 43, 10, p. 1005-1012 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    360 Scopus citations
  • Genome-wide association study of heavy smoking and daily/nondaily smoking in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

    Saccone, N. L., Emery, L. S., Sofer, T., Gogarten, S. M., Becker, D. M., Bottinger, E. P., Chen, L. S., Culverhouse, R. C., Duan, W., Hancock, D. B., Hosgood, H. D., Johnson, E. O., Loos, R. J. F., Louie, T., Papanicolaou, G., Perreira, K. M., Rodriquez, E. J., Schurmann, C., Stilp, A. M., Szpiro, A. A., & 8 othersTalavera, G. A., Taylor, K. D., Thrasher, J. F., Yanek, L. R., Laurie, C. C., Pérez-Stable, E. J., Bierut, L. J. & Kaplan, R. C., Mar 6 2018, In: Nicotine and Tobacco Research. 20, 4, p. 448-457 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN)

    Wojczynski, M. K., Parnell, L. D., Pollin, T. I., Lai, C. Q., Feitosa, M. F., O'Connell, J. R., Frazier-Wood, A. C., Gibson, Q., Aslibekyan, S., Ryan, K. A., Province, M. A., Tiwari, H. K., Ordovas, J. M., Shuldiner, A. R., Arnett, D. K. & Borecki, I. B., Oct 1 2015, In: Metabolism: clinical and experimental. 64, 10, p. 1359-1371 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    30 Scopus citations
  • Genome-wide association study to identify common variants associated with brachial circumference: A meta-analysis of 14 cohorts

    Boraska, V., Day-Williams, A., Franklin, C. S., Elliott, K. S., Panoutsopoulou, K., Tachmazidou, I., Albrecht, E., Bandinelli, S., Beilin, L. J., Bochud, M., Cadby, G., Ernst, F., Evans, D. M., Hayward, C., Hicks, A. A., Huffman, J., Huth, C., James, A. L., Klopp, N., Kolcic, I., & 46 othersKutalik, Z., Lawlor, D. A., Musk, A. W., Pehlic, M., Pennell, C. E., Perry, J. R. B., Peters, A., Polasek, O., Pourcain, B. S., Ring, S. M., Salvi, E., Schipf, S., Staessen, J. A., Teumer, A., Timpson, N., Vitart, V., Warrington, N. M., Yaghootkar, H., Zemunik, T., Zgaga, L., An, P., Anttila, V., Borecki, I. B., Holmen, J., Ntalla, I., Palotie, A., Pietiläinen, K. H., Wedenoja, J., Winsvold, B. S., Dedoussis, G. V., Kaprio, J., Province, M. A., Zwart, J. A., Burnier, M., Campbell, H., Cusi, D., Davey Smith, G., Frayling, T. M., Gieger, C., Palmer, L. J., Pramstaller, P. P., Rudan, I., Völzke, H., Wichmann, H. E., Wright, A. F. & Zeggini, E., Mar 29 2012, In: PloS one. 7, 3, e31369.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Genome-wide characterization of endogenous retroviruses in the bat Myotis lucifugus reveals recent and diverse infections

    Zhuo, X., Rho, M. & Feschotte, C., 2013, In: Journal of virology. 87, 15, p. 8493-8501 9 p.

    Research output: Contribution to journalArticlepeer-review

    32 Scopus citations
  • Genome-wide chromatin accessibility analyses provide a map for enhancing optic nerve regeneration

    Pita-Thomas, W., Gonçalves, T. M., Kumar, A., Zhao, G. & Cavalli, V., Dec 2021, In: Scientific reports. 11, 1, 14924.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • Genome-wide discovery of loci influencing chemotherapy cytotoxicity

    Watters, J. W., Kraja, A., Meucci, M. A., Province, M. A. & McLeod, H. L., Aug 10 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 32, p. 11809-11814 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    127 Scopus citations
  • Genome-wide DNA methylation profiling of primary colorectal laterally spreading tumors identifies disease-specific epimutations on common pathways

    Zhu, L., Yan, F., Wang, Z., Dong, H., Bian, C., Wang, T., Yu, E. & Li, J., Nov 15 2018, In: International Journal of Cancer. 143, 10, p. 2488-2498 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    19 Scopus citations
  • Genome-Wide Epistatic Network Analyses of Semantic Fluency in Older Adults

    Tan, Q., Li, W., Nygaard, M., An, P., Feitosa, M., Wojczynski, M. K., Zmuda, J., Arbeev, K., Ukraintseva, S., Yashin, A., Christensen, K. & Mengel-From, J., May 2024, In: International journal of molecular sciences. 25, 10, 5257.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of Nitric oxide synthase and Fd59a/Fox-D

    Lacin, H., Rusch, J., Yeh, R. T., Fujioka, M., Wilson, B. A., Zhu, Y., Robie, A. A., Mistry, H., Wang, T., Jaynes, J. B. & Skeath, J. B., Apr 1 2014, In: Developmental Biology. 388, 1, p. 117-133 17 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    23 Scopus citations
  • Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

    Smith, C. E., Follis, J. L., Dashti, H. S., Tanaka, T., Graff, M., Fretts, A. M., Kilpeläinen, T. O., Wojczynski, M. K., Richardson, K., Nalls, M. A., Schulz, C. A., Liu, Y., Frazier-Wood, A. C., van Eekelen, E., Wang, C., de Vries, P. S., Mikkilä, V., Rohde, R., Psaty, B. M., Hansen, T., & 43 othersFeitosa, M. F., Lai, C. Q., Houston, D. K., Ferruci, L., Ericson, U., Wang, Z., de Mutsert, R., Oddy, W. H., de Jonge, E. A. L., Seppälä, I., Justice, A. E., Lemaitre, R. N., Sørensen, T. I. A., Province, M. A., Parnell, L. D., Garcia, M. E., Bandinelli, S., Orho-Melander, M., Rich, S. S., Rosendaal, F. R., Pennell, C. E., Kiefte-de Jong, J. C., Kähönen, M., Young, K. L., Pedersen, O., Aslibekyan, S., Rotter, J. I., Mook-Kanamori, D. O., Zillikens, M. C., Raitakari, O. T., North, K. E., Overvad, K., Arnett, D. K., Hofman, A., Lehtimäki, T., Tjønneland, A., Uitterlinden, A. G., Rivadeneira, F., Franco, O. H., German, J. B., Siscovick, D. S., Cupples, L. A. & Ordovás, J. M., Feb 1 2018, In: Molecular Nutrition and Food Research. 62, 3, 1700347.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • Genome-wide linkage analyses for age at diagnosis of hypertension and early-onset hypertension in the HyperGEN study

    Wilk, J. B., Djousse, L., Arnett, D. K., Hunt, S. C., Province, M. A., Heiss, G. & Myers, R. H., Sep 2004, In: American Journal of Hypertension. 17, 9, p. 839-844 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    33 Scopus citations
  • Genome-wide linkage analysis for loci affecting pulse pressure: The Family Blood Pressure Program

    Bielinski, S. J., Lynch, A. I., Miller, M. B., Weder, A., Cooper, R., Oberman, A., Chen, Y. D. I., Turner, S. T., Fornage, M., Province, M. & Arnett, D. K., Dec 2005, In: Hypertension. 46, 6, p. 1286-1293 8 p.

    Research output: Contribution to journalArticlepeer-review

    40 Scopus citations
  • Genome-wide linkage analysis of carotid artery traits in exceptionally long-lived families

    for the Long Life Family Study, Dec 2019, In: Atherosclerosis. 291, p. 19-26 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Genome-wide linkage analysis of lipids in the hypertension genetic epidemiology network (HyperGEN) blood pressure study

    Coon, H., Leppert, M. F., Eckfeldt, J. H., Oberman, A., Myers, R. H., Peacock, J. M., Province, M. A., Hopkins, P. N. & Heiss, G., 2001, In: Arteriosclerosis, thrombosis, and vascular biology. 21, 12, p. 1969-1976 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    66 Scopus citations
  • Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease

    Silverman, E. K., Palmer, L. J., Mosley, J. D., Barth, M., Senter, J. M., Brown, A., Drazen, J. M., Kwiatkowski, D. J., Chapman, H. A., Campbell, E. J., Province, M. A., Rao, D. C., Reilly, J. J., Ginns, L. C., Speizer, F. E. & Weiss, S. T., 2002, In: American journal of human genetics. 70, 5, p. 1229-1239 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    160 Scopus citations
  • Genome-wide linkage analysis of severe, early-onset chronic obstructive pulmonary disease: Airflow obstruction and chronic bronchitis phenotypes

    Silverman, E. K., Mosley, J. D., Palmer, L. J., Barth, M., Senter, J. M., Brown, A., Drazen, J. M., Kwiatkowski, D. J., Chapman, H. A., Campbell, E. J., Province, M. A., Rao, D. C., Reilly, J. J., Ginns, L. C., Speizer, F. E. & Weiss, S. T., Mar 15 2002, In: Human molecular genetics. 11, 6, p. 623-632 10 p.

    Research output: Contribution to journalArticlepeer-review

    106 Scopus citations
  • Genome-wide linkage analysis of systolic and diastolic blood pressure: The Quebec family study

    Rice, T., Rankinen, T., Province, M. A., Chagnon, Y. C., Pérusse, L., Borecki, I. B., Bouchard, C. & Rao, D. C., Oct 17 2000, In: Circulation. 102, 16, p. 1956-1963 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    204 Scopus citations
  • Genome-wide linkage analysis replicates susceptibility locus for fasting plasma triglycerides: NHLBI Family Heart Study

    Arnett, D. K., Miller, M. B., Coon, H., Ellison, R. C., North, K. E., Province, M., Leppert, M. & Eckfeldt, J. H., 2004, In: Human genetics. 115, 6, p. 468-474 7 p.

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations