Department of Genetics

MATRIX SEARCH 1.0: A computer program that scans DNA sequences for transcriptional elements using a database of weight matrices

Chen, Q. K., Hertz, G. Z. & Stormo, G. D., Oct 1995, In: Bioinformatics. 11, 5, p. 563-566 4 p.

Research output: Contribution to journal › Article › peer-review

114 Scopus citations

Maximally efficient modeling of DNA sequence motifs at all levels of complexity

Stormo, G. D., Apr 2011, In: Genetics. 187, 4, p. 1219-1224 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Measuring quantitative effects of methylation on transcription factor–DNA binding affinity

Zuo, Z., Roy, B., Chang, Y. K., Granas, D. & Stormo, G. D., 2017, In: Science Advances. 3, 11, eaao1799.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Measuring transcription factor binding and gene expression using barcoded self-reporting transposon calling cards and transcriptomes

Lalli, M., Yen, A., Thopte, U., Dong, F., Moudgil, A., Chen, X., Milbrandt, J., Dougherty, J. D. & Mitra, R. D., Sep 1 2022, In: NAR Genomics and Bioinformatics. 4, 3, lqac061.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Mechanism of homophilic binding mediated by ninjurin, a novel widely expressed adhesion molecule

Araki, T., Zimonjic, D. B., Popescu, N. C. & Milbrandt, J., Aug 22 1997, In: Journal of Biological Chemistry. 272, 34, p. 21373-21380 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

79 Scopus citations

Mechanism of shape determination in motile cells

Keren, K., Pincus, Z., Allen, G. M., Barnhart, E. L., Marriott, G., Mogilner, A. & Theriot, J. A., May 22 2008, In: Nature. 453, 7194, p. 475-480 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

574 Scopus citations

Mechanisms of nucleotide trafficking during siRNA delivery to endothelial cells using perfluorocarbon nanoemulsions

Kaneda, M. M., Sasaki, Y., Lanza, G. M., Milbrandt, J. & Wickline, S. A., Apr 2010, In: Biomaterials. 31, 11, p. 3079-3086 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Mechanisms underlying familial aggregation of exceptional health and survival: A three-generation cohort study

Christensen, K., Wojczynski, M. K., Pedersen, J. K., Larsen, L. A., Kløjgaard, S., Skytthe, A., McGue, M., Vaupel, J. W. & Province, M. A., Oct 1 2020, In: Aging Cell. 19, 10, e13228.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Mecp2 deletion results in profound alterations of developmental and adult functional connectivity

Rahn, R. M., Yen, A., Chen, S., Gaines, S. H., Bice, A. R., Brier, L. M., Swift, R. G., Lee, L. L., Maloney, S. E., Culver, J. P. & Dougherty, J. D., Jun 15 2023, In: Cerebral Cortex. 33, 12, p. 7436-7453 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

MeCP2 Represses Enhancers through Chromosome Topology-Associated DNA Methylation

Clemens, A. W., Wu, D. Y., Moore, J. R., Christian, D. L., Zhao, G. & Gabel, H. W., Jan 16 2020, In: Molecular cell. 77, 2, p. 279-293.e8

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Medicago truncatula transporter database: A comprehensive database resource for M. truncatula transporters

Miao, Z., Li, D., Zhang, Z., Dong, J., Su, Z. & Wang, T., Feb 6 2012, In: BMC genomics. 13, 1, 60.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Mendelian analysis of the organization of actin sequences in Physarum polycephalum

Schedl, T. & Dove, W. F., Sep 5 1982, In: Journal of Molecular Biology. 160, 1, p. 41-57 17 p.

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

Okada, Y., Sim, X., Go, M. J., Wu, J. Y., Gu, D., Takeuchi, F., Takahashi, A., Maeda, S., Tsunoda, T., Chen, P., Lim, S. C., Wong, T. Y., Liu, J., Young, T. L., Aung, T., Seielstad, M., Teo, Y. Y., Kim, Y. J., Lee, J. Y. & Han, B. G. & 469 others, Kang, D., Chen, C. H., Tsai, F. J., Chang, L. C., Fann, S. J., Mei, H., Rao, D. C., Hixson, J. E., Chen, S., Katsuya, T., Isono, M., Ogihara, T., Chambers, J. C., Zhang, W., Kooner, J. S., Albrecht, E., Yamamoto, K., Kubo, M., Nakamura, Y., Kamatani, N., Kato, N., He, J., Chen, Y. T., Cho, Y. S., Tai, E. S., Tanaka, T., Chambers, J. C., Zhang, W., Lord, G. M., van der Harst, P., Lawlor, D. A., Sehmi, J. S., Gale, D. P., Wass, M. N., Ahmadi, K. R., Bakker, S. J., Beckmann, J., Bilo, H. J., Bochud, M., Brown, M. J., Caulfield, M. J., Connell, J. M., Cook, H. T., Cotlarciuc, I., Smith, G. D., de Silva, R., Deng, G., Devuyst, O., Dikkeschei, L. D., Dimkovic, N., Dockrell, M., Dominiczak, A., Ebrahim, S., Eggermann, T., Farrall, M., Ferrucci, L., Floege, J., Forouhi, N. G., Gansevoort, R. T., Han, X., Hedblad, B., van der Heide, J. J., Hepkema, B. G., Hernandez-Fuentes, M., Hypponen, E., Johnson, T., de Jong, P. E., Kleefstra, N., Lagou, V., Lapsley, M., Li, Y., Loos, R. J., Luan, J., Luttropp, K., Maréchal, C., Melander, O., Munroe, P. B., Nordfors, L., Parsa, A., Peltonen, L., Penninx, B. W., Perucha, E., Pouta, A., Prokopenko, I., Roderick, P. J., Ruokonen, A., Samani, N. J., Sanna, S., Schalling, M., Schlessinger, D., Schlieper, G., Seelen, M. A., Shuldiner, A. R., Sjögren, M., Smit, J. H., Snieder, H., Soranzo, N., Spector, T. D., Stenvinkel, P., Sternberg, M. J., Swaminathan, R., Tanaka, T., Ubink-Veltmaat, L. J., Uda, M., Vollenweider, P., Wallace, C., Waterworth, D., Zerres, K., Waeber, G., Wareham, N. J., Maxwell, P. H., McCarthy, M. I., Jarvelin, M. R., Mooser, V., Abecasis, G. R., Lightstone, L., Scott, J., Navis, G., Elliott, P., Kooner, J. S., Köttgen, A., Pattaro, C., Böger, C. A., Fuchsberger, C., Olden, M., Glazer, N. L., Parsa, A., Gao, X., Yang, Q., Smith, A. V., O'connell, J. R., Li, M., Schmidt, H., Tanaka, T., Isaacs, A., Ketkar, S., Hwang, S. J., Johnson, A. D., Dehghan, A., Teumer, A., Paré, G., Atkinson, E. J., Zeller, T., Lohman, K., Cornelis, M. C., Probst-Hensch, N. M., Kronenberg, F., Tönjes, A., Hayward, C., Aspelund, T., Eiriksdottir, G., Launer, L. J., Harris, T. B., Rampersaud, E., Mitchell, B. D., Arking, D. E., Boerwinkle, E., Struchalin, M., Cavalieri, M., Singleton, A., Giallauria, F., Metter, J., de Boer, I. H., Haritunians, T., Lumley, T., Siscovick, D., Psaty, B. M., Zillikens, M. C., Oostra, B. A., Feitosa, M., Province, M., de Andrade, M., Turner, S. T., Schillert, A., Ziegler, A., Wild, P. S., Schnabel, R. B., Wilde, S., Munzel, T. F., Leak, T. S., Illig, T., Klopp, N., Meisinger, C., Wichmann, H. E., Koenig, W., Zgaga, L., Zemunik, T., Kolcic, I., Minelli, C., Hu, F. B., Johansson, Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Schreiber, S., Aulchenko, Y. S., Felix, J. F., Rivadeneira, F., Uitterlinden, A. G., Hofman, A., Imboden, M., Nitsch, D., Brandstätter, A., Kollerits, B., Kedenko, L., Mägi, R., Stumvoll, M., Kovacs, P., Boban, M., Campbell, S., Endlich, K., Völzke, H., Kroemer, H. K., Nauck, M., Völker, U., Polasek, O., Vitart, V., Badola, S., Parker, A. N., Ridker, P. M., Kardia, S. L., Blankenberg, S., Liu, Y., Curhan, G. C., Franke, A., Rochat, T., Paulweber, B., Prokopenko, I., Wang, W., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Shlipak, M. G., van Duijn, C. M., Borecki, I., Krämer, B. K., Rudan, I., Gyllensten, U., Wilson, J. F., Witteman, J. C., Pramstaller, P. P., Rettig, R., Hastie, N., Chasman, D. I., Kao, W. H., Heid, I. M., Fox, C. S., Köttgen, A., Albrecht, E., Teumer, A., Vitart, V., Krumsiek, J., Hundertmark, C., Pistis, G., Ruggiero, D., O'seaghdha, M., Haller, T., Yang, Q., Tanaka, T., Johnson, A. D., Kutalik, Z., Smith, A. V., Shi, J., Struchalin, M., Middelberg, P. S., Brown, M. J., Gaffo, A. L., Pirastu, N., Li, G., Hayward, C., Zemunik, T., Huffman, J., Yengo, L., Zhao, J. H., Demirkan, A., Feitosa, M. F., Liu, X., Malerba, G., Lopez, L. M., Li, X., Kleber, M. E., Hicks, A. A., Nolte, I. M., Johansson, A., Murgia, F., Wild, S. H., Bakker, S. J., Peden, J. F., Dehghan, A., Steri, M., Tenesa, A., Lagou, V., Salo, P., Mangino, M., Rose, L. M., Lehtimäki, T., Woodward, O. M., Tin, A., Müller, C., Oldmeadow, C., Putku, M., Czamara, D., Kraft, P., Frogheri, L., Thun, G. A., Grotevendt, A., Gislason, G. K., Harris, T. B., Launer, L. J., McArdle, P., Shuldiner, A. R., Boerwinkle, E., Schmidt, H., Schallert, M., Martin, N. G., Montgomery, G. W., Kubo, M., Nakamura, Y., Tanaka, T., Jacobs, D. R., Liu, K., D'adamo, P., Ulivi, S., Rotter, J. I., Psaty, B. M., Vollenweider, P., Waeber, G., Campbell, S., Devuyst, O., Navaro, P., Kolcic, I., Hastie, N., Balkau, B., Froguel, P., Esko, T., Salumets, A., Khaw, K. T., Langenberg, C., Isaacs, A., Kraja, A., Zhang, Q., Wild, P. S., Scott, R. J., Holliday, E. G., Org, E., Viigimaa, M., Bandinelli, S., Metter, J. E., Lupo, A., Trabetti, E., Sorice, R., Döring, A., Lattka, E., Strauch, K., Theis, F., Waldenberger, M., Wichmann, H. E., Davies, G., Gow, A. J., Bruinenberg, M., Stolk, R. P., Kooner, J. S., Zhang, W., Winkelmann, B. R., Boehm, B. O., Lucae, S., Penninx, B. W., Smit, J. H., Curhan, G., Mudgal, P., Plenge, R. M., Portas, L., Persico, I., Kirin, M., Wilson, J. F., Mateo Leach, I., van Gilst, W. H., Goel, A., Ongen, H., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Imboden, M., von Eckardstein, A., Cucca, F., Nagaraja, R., Piras, M. G., Nauck, M., Schurmann, C., Budde, K., Ernst, F., Farrington, S. M., Theodoratou, E., Prokopenko, I., Stumvoll, M., Jula, A., Perola, M., Salomaa, V., Shin, S. Y., Spector, T. D., Sala, C., Ridker, P. M., Kähönen, M., Viikari, J., Hengstenberg, C., Nelson, C. P., Meschia, J. F., Nalls, M. A., Sharma, P., Singleton, A. B., Kamatani, N., Zeller, T., Burnier, M., Attia, J., Laan, M., Klopp, N., Hillege, H. L., Kloiber, S., Choi, H., Pirastu, M., Tore, S., Probst-Hensch, N. M., Völzke, H., Gudnason, V., Parsa, A., Schmidt, R., Whitfield, J. B., Fornage, M., Gasparini, P., Siscovick, D. S., Polasek, O., Campbell, H., Rudan, I., Bouatia-Naji, N., Metspalu, A., Loos, R. J., van Duijn, C. M., Borecki, I. B., Gambaro, G., Deary, I. J., Wolffenbuttel, B. H., Chambers, J. C., März, W., Pramstaller, P. P., Snieder, H., Gyllensten, U., Wright, A. F., Navis, G., Watkins, H., Witteman, J. C., Sanna, S., Schipf, S., Dunlop, M. G., Tönjes, A., Ripatti, S., Soranzo, N., Toniolo, D., Chasman, D. I., Raitakari, O., Kao, W. H., Ciullo, M., Fox, C. S., Caulfield, M., Bochud, M. & Gieger, C., Aug 1 2012, In: Nature Genetics. 44, 8, p. 904-909 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

240 Scopus citations

Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts

Nettleton, J. A., Hivert, M. F., Lemaitre, R. N., McKeown, N. M., Mozaffarian, D., Tanaka, T., Wojczynski, M. K., Hruby, A., Djoussé, L., Ngwa, J. S., Follis, J. L., Dimitriou, M., Ganna, A., Houston, D. K., Kanoni, S., Mikkilä, V., Manichaikul, A., Ntalla, I., Renström, F. & Sonestedt, E. & 45 others, Van Rooij, F. J. A., Bandinelli, S., De Koning, L., Ericson, U., Hassanali, N., Kiefte-De Jong, J. C., Lohman, K. K., Raitakari, O., Papoutsakis, C., Sjogren, P., Stirrups, K., Ax, E., Deloukas, P., Groves, C. J., Jacques, P. F., Johansson, I., Liu, Y., McCarthy, M. I., North, K., Viikari, J., Zillikens, M. C., Dupuis, J., Hofman, A., Kolovou, G., Mukamal, K., Prokopenko, I., Rolandsson, O., Seppälä, I., Cupples, L. A., Hu, F. B., Kähönen, M., Uitterlinden, A. G., Borecki, I. B., Ferrucci, L., Jacobs, D. R., Kritchevsky, S. B., Orho-Melander, M., Pankow, J. S., Lehtimäki, T., Witteman, J. C. M., Ingelsson, E., Siscovick, D. S., Dedoussis, G., Meigs, J. B. & Franks, P. W., Jan 2013, In: American journal of epidemiology. 177, 2, p. 103-115 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

70 Scopus citations

Meta-analysis methodology for combining non-parametric sibpair linkage results: Genetic homogeneity and identical markers

Gu, C., Province, M., Todorov, A. & Rao, D. C., 1998, In: Genetic Epidemiology. 15, 6, p. 609-626 18 p.

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Tobin, M. D., London, S. J., Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., Obeidat, M., Province, M. A., Gao, W., Qaiser, B., Porteous, D. J., Cassano, P. A., Ahluwalia, T. S., Grarup, N., Li, J., Altmaier, E., Marten, J. & Harris, S. E. & 87 others, Manichaikul, A., Pottinger, T. D., Li-Gao, R., Lind-Thomsen, A., Mahajan, A., Lahousse, L., Imboden, M., Teumer, A., Prins, B., Lyytikäinen, L. P., Eiriksdottir, G., Franceschini, N., Sitlani, C. M., Brody, J. A., Bossé, Y., Timens, W., Kraja, A., Loukola, A., Tang, W., Liu, Y., Bork-Jensen, J., Justesen, J. M., Linneberg, A., Lange, L. A., Rawal, R., Karrasch, S., Huffman, J. E., Smith, B. H., Davies, G., Burkart, K. M., Mychaleckyj, J. C., Bonten, T. N., Enroth, S., Lind, L., Brusselle, G. G., Kumar, A., Stubbe, B., Kähönen, M., Wyss, A. B., Psaty, B. M., Heckbert, S. R., Hao, K., Rantanen, T., Kritchevsky, S. B., Lohman, K., Skaaby, T., Pisinger, C., Hansen, T., Schulz, H., Polasek, O., Campbell, A. I., Starr, J. M., Rich, S. S., Mook-Kanamori, D. O., Johansson, Å., Ingelsson, E., Uitterlinden, A. G., Weiss, S., Raitakari, O. T., Gudnason, V., North, K. E., Gharib, S. A., Sin, D. D., Taylor, K. D., O'Connor, G. T., Kaprio, J., Harris, T. B., Pederson, O., Vestergaard, H., Wilson, J. G., Strauch, K., Hayward, C., Kerr, S. M., Deary, I. J., Barr, R. G., de Mutsert, R., Gyllensten, U., Morris, A. P., Ikram, M. A., Probst-Hensch, N., Gläser, S., Zeggini, E., Lehtimäki, T., Strachan, D. P., Dupuis, J., Morrison, A. C. & Hall, I. P., 2018, In: Wellcome Open Research. 3, 4.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Meta-analysis of exome array data identifies six novel genetic loci for lung function.

Understanding Society Scientific group, 2018, In: Wellcome Open Research. 3, 4.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Meta-analysis of gene-environment interaction: Joint estimation of SNP and SNP × environment regression coefficients

Manning, A. K., LaValley, M., Liu, C. T., Rice, K., An, P., Liu, Y., Miljkovic, I., Rasmussen-Torvik, L., Harris, T. B., Province, M. A., Borecki, I. B., Florez, J. C., Meigs, J. B., Cupples, L. A. & Dupuis, J., Jan 2011, In: Genetic Epidemiology. 35, 1, p. 11-18 8 p.

Research output: Contribution to journal › Article › peer-review

136 Scopus citations

Meta-analysis of gene-level associations for rare variants based on single-variant statistics

Hu, Y. J., Berndt, S. I., Gustafsson, S., Ganna, A., Ingelsson, E., Hirschhorn, J., North, K. E., Lin, D. Y., Berndt, S. I., Gustafsson, S., Mägi, R., Ganna, A., Wheeler, E., Feitosa, M. F., Justice, A. E., Monda, K. L., Croteau-Chonka, D. C., Day, F. R., Esko, T. & Fall, T. & 307 others, Ferreira, T., Gentilini, D., Jackson, A. U., Luan, J., Randall, J. C., Vedantam, S., Willer, C. J., Winkler, T. W., Wood, A. R., Workalemahu, T., Hu, Y. J., Lee, S. H., Liang, L., Lin, D. Y., Min, J. L., Neale, B. M., Thorleifsson, G., Yang, J., Albrecht, E., Amin, N., Bragg-Gresham, J. L., Cadby, G., Heijer, M. D., Eklund, N., Fischer, K., Goel, A., Hottenga, J. J., Huffman, J. E., Jarick, I., Johansson, A., Johnson, T., Kanoni, S., Kleber, M. E., König, I. R., Kristiansson, K., Kutalik, Z., Lamina, C., Lecoeur, C., Li, G., Mangino, M., McArdle, W. L., Medina-Gomez, C., Müller-Nurasyid, M., Ngwa, J. S., Nolte, I. M., Paternoster, L., Pechlivanis, S., Perola, M., Peters, M. J., Preuss, M., Rose, L. M., Shi, J., Shungin, D., Smith, A. V., Strawbridge, R. J., Surakka, I., Teumer, A., Trip, M. D., Tyrer, J., Vliet-Ostaptchouk, J. V. V., Vandenput, L., Waite, L. L., Zhao, J. H., Absher, D., Asselbergs, F. W., Atalay, M., Attwood, A. P., Balmforth, A. J., Basart, H., Beilby, J., Bonnycastle, L. L., Brambilla, P., Bruinenberg, M., Campbell, H., Chasman, D. I., Chines, P. S., Connell, J. M., Cookson, W., Faire, U. D., Vegt, F. D., Dei, M., Dimitriou, M., Edkins, S., Estrada, K., Evans, D. M., Farrall, M., Ferrario, M. M., Ferrières, J., Franke, L., Frau, F., Gejman, P. V., Grallert, H., Grönberg, H., Gudnason, V., Hall, A. S., Hall, P., Hartikainen, A. L., Hayward, C., Heard-Costa, N. L., Heath, A. C., Hebebrand, J., Homuth, G., Hu, F. B., Hunt, S. E., Hyppönen, E., Iribarren, C., Jacobs, K. B., Jansson, J. O., Jula, A., Kähönen, M., Kathiresan, S., Kee, F., Khaw, K. T., Kivimaki, M., Koenig, W., Kraja, A. T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Laitinen, J. H., Lakka, T. A., Langenberg, C., Launer, L. J., Lind, L., Lindström, J., Liu, J., Liuzzi, A., Lokki, M. L., Lorentzon, M., Magnusson, P. A. M., Magnusson, P. A. M., Manunta, P., Marek, D., März, W., Leach, I. M., McKnight, B., Medland, S. E., Mihailov, E., Milani, L., Montgomery, G. W., Mooser, V., Mühleisen, T. W., Munroe, P. B., Musk, A. W., Narisu, N., Navis, G., Nicholson, G., Nohr, E. A., Ong, K. K., Oostra, B. A., Palmer, C. N. A., Palotie, A., Peden, J. F., Pedersen, N., Peters, A., Polasek, O., Pouta, A., Pramstaller, P. P., Prokopenko, I., Pütter, C., Radhakrishnan, A., Raitakari, O., Rendon, A., Rivadeneira, F., Rudan, I., Saaristo, T. E., Sambrook, J. G., Sanders, A. R., Sanna, S., Saramies, J., Schipf, S., Schreiber, S., Schunkert, H., Shin, S. Y., Signorini, S., Sinisalo, J., Skrobek, B., Soranzo, N., Stancáková, A., Stark, K., Stephens, J. C., Stirrups, K., Stolk, R. P., Stumvoll, M., Swift, A. J., Theodoraki, E. V., Thorand, B., Tregouet, D. A., Tremoli, E., Klauw, M. M. V. D., Meurs, J. B. J. V., Vermeulen, S. H., Viikari, J., Virtamo, J., Vitart, V., Waeber, G., Wang, Z., Widén, E., Wild, S. H., Willemsen, G., Winkelmann, B. R., Witteman, J. C. M., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zillikens, M. C., Amouyel, P., Boehm, B. O., Boerwinkle, E., Boomsma, D. I., Caulfield, M. J., Chanock, S. J., Cupples, L. A., Cusi, D., Dedoussis, G. V., Erdmann, J., Eriksson, J. G., Franks, P. W., Froguel, P., Gieger, C., Gyllensten, U., Hamsten, A., Harris, T. B., Hengstenberg, C., Hicks, A. A., Hingorani, A., Hinney, A., Hofman, A., Hovingh, K. G., Hveem, K., Illig, T., Jarvelin, M. R., Jöckel, K. H., Keinanen-Kiukaanniemi, S. M., Kiemeney, L. A., Kuh, D., Laakso, M., Lehtimäki, T., Levinson, D. F., Martin, N. G., Metspalu, A., Morris, A. D., Nieminen, M. S., Njølstad, I., Ohlsson, C., Oldehinkel, A. J., Ouwehand, W. H., Palmer, L. J., Penninx, B., Power, C., Province, M. A., Psaty, B. M., Qi, L., Rauramaa, R., Ridker, P. M., Ripatti, S., Salomaa, V., Samani, N. J., Snieder, H., Sørensen, T. I. A., Spector, T. D., Stefansson, K., Tönjes, A., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Harst, P. V. D., Vollenweider, P., Wallaschofski, H., Wareham, N. J., Watkins, H., Wichmann, H. E., Wilson, J. F., Abecasis, G. R., Assimes, T. L., Barroso, I., Boehnke, M., Borecki, I. B., Deloukas, P., Fox, C. S., Frayling, T., Groop, L. C., Haritunian, T., Heid, I. M., Hunter, D., Kaplan, R. C., Karpe,MiriamMoffatt, F., Mohlke, K. L., O’Connell, J. R., Pawitan, Y., Schadt, E. E., Schlessinger, D., Steinthorsdottir, V., Strachan, D. P., Thorsteinsdottir, U., Duijn, C. M. V., Visscher, P. M., Blasio, A. M. D., Hirschhorn, J. N., Lindgren, C. M., Morris, A. P., Meyre, D., Scherag, A., McCarthy, M. I., Speliotes, E. K., North, K. E. & Loos, R. J. F., Aug 8 2013, In: American journal of human genetics. 93, 2, p. 236-248 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

Meta-analysis of genetic linkage to quantitative trait loci with study- specific covariates: A mixed-effects model

Gu, C., Province, M. & Rao, D. C., 1999, In: Genetic Epidemiology. 17, SUPPL. 1, p. S599-S604

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

The MAGIC investigators & The GIANT Consortium, Aug 7 2014, In: PLoS genetics. 10, 8, e1004517.

Research output: Contribution to journal › Article › peer-review

Open Access

173 Scopus citations

Meta-analysis of genome-wide scans for blood pressure in African American and Nigerian samples: The National Heart, Lung, and Blood Institute GeneLink Project

Rice, T., Cooper, R. S., Wu, X., Bouchard, C., Rankinen, T., Rao, D. C., Jaquish, C. E., Fabsitz, R. R. & Province, M. A., Mar 2006, In: American Journal of Hypertension. 19, 3, p. 270-274 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Metabolic aspects of neuronal degeneration: From a NAD⁺ point of view

Sasaki, Y., Feb 2019, In: Neuroscience Research. 139, p. 9-20 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

26 Scopus citations

Metabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance

Beirowski, B., Babetto, E., Golden, J. P., Chen, Y. J., Yang, K., Gross, R. W., Patti, G. J. & Milbrandt, J., Oct 1 2014, In: Nature neuroscience. 17, 10, p. 1351-1361 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

147 Scopus citations

Metabolic syndrome components in murine models

Lawson, H. A. & Cheverud, J. M., Mar 2010, In: Endocrine, Metabolic and Immune Disorders - Drug Targets. 10, 1, p. 25-40 16 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

18 Scopus citations

Methamphetamine-induced region-specific transcriptomic and epigenetic changes in the brain of male rats

Miao, B., Xing, X., Bazylianska, V., Madden, P., Moszczynska, A. & Zhang, B., Dec 2023, In: Communications Biology. 6, 1, 991.

Research output: Contribution to journal › Article › peer-review

Open Access

Methods for adjusting population structure and familial relatedness in association test for collective effect of multiple rare variants on quantitative traits

Zhang, Q., Chung, D., Kraja, A., Borecki, I. I. & Province, M. A., 2011, In: BMC Proceedings. 5, SUPPL. 9, S35.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Methods for analysis in pharmacogenomics: Lessons from the Pharmacogenetics Research Network Analysis group

Srinivasan, B. S., Chen, J., Cheng, C., Conti, D., Duan, S., Fridley, B. L., Gu, X., Haines, J. L., Jorgenson, E., Kraja, A., Lasky-Su, J., Li, L., Rodin, A., Wang, D., Province, M. & Ritchie, M. D., 2009, In: Pharmacogenomics. 10, 2, p. 243-251 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Methods for detecting methylation by SNP interaction in GAW20 simulation

Warwick Daw, E., Hicks, J., Lenzini, P., Lin, S. J., Wang, J., Williams, C., An, P., Province, M. A. & Kraja, A. T., Sep 17 2018, In: BMC Proceedings. 12, 37.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene

Milbrandt, J. D., Heintz, N. H., White, W. C., Rothman, S. M. & Hamlin, J. L., 1981, In: Unknown Journal. 78, 10 I, p. 6043-6047 5 p.

Research output: Contribution to journal › Article › peer-review

109 Scopus citations

MethylCRF, an algorithm for estimating absolute methylation levels at single CpG resolution from methylation enrichment and restriction enzyme sequencing methods

Stevens, M., Cheng, J. B., Xie, M., Costello, J. F. & Wang, T., Apr 3 2013, Research in Computational Molecular Biology - 17th Annual International Conference, RECOMB 2013, Proceedings. p. 266-268 3 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 7821 LNBI).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

MethylC Track: Visual integration of single-base resolution DNA methylation data on the WashU EpiGenome Browser

Zhou, X., Li, D., Lowdon, R. F., Costello, J. F. & Wang, T., Aug 1 2014, In: Bioinformatics. 30, 15, p. 2206-2207 2 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

METT-10, a putative methyltransferase, inhibits germ cell proliferative fate in Caenorhabditis elegans

Dorsett, M., Westlund, B. & Schedl, T., Sep 2009, In: Genetics. 183, 1, p. 233-247 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids

Sadovsky, Y., Crawford, P. A., Woodson, K. G., Polish, J. A., Clements, M. A., Tourtellotte, L. M., Simburger, K. & Milbrandt, J., Nov 21 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 24, p. 10939-10943 5 p.

Research output: Contribution to journal › Article › peer-review

405 Scopus citations

Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis

Jain, S., Naughton, C. K., Yang, M., Strickland, A., Vij, K., Encinas, M., Golden, J., Gupta, A., Heuckeroth, R., Johnson, E. M. & Milbrandt, J., Nov 2004, In: Development. 131, 21, p. 5503-5513 11 p.

Research output: Contribution to journal › Article › peer-review

113 Scopus citations

Mice lacking sister chromatid cohesion protein PDS5B exhibit developmental abnormalities reminiscent of Cornelia de Lange syndrome

Zhang, B., Jain, S., Song, H., Fu, M., Heuckeroth, R. O., Erlich, J. M., Jay, P. Y. & Milbrandt, J., Sep 2007, In: Development. 134, 17, p. 3191-3201 11 p.

Research output: Contribution to journal › Article › peer-review

89 Scopus citations

Mice lacking the immediate early gene Egr3 respond to the anti-aggressive effects of clozapine yet are relatively resistant to its sedating effects

Gallitano-Mendel, A., Wozniak, D. F., Pehek, E. A. & Milbrandt, J., May 2008, In: Neuropsychopharmacology. 33, 6, p. 1266-1275 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity

Ohsawa, K., Imai, Y., Sasaki, Y. & Kohsaka, S., Feb 2004, In: Journal of Neurochemistry. 88, 4, p. 844-856 13 p.

Research output: Contribution to journal › Article › peer-review

272 Scopus citations

Microglia and macrophages in brain homeostasis and disease

Li, Q. & Barres, B. A., Apr 1 2018, In: Nature Reviews Immunology. 18, 4, p. 225-242 18 p.

Research output: Contribution to journal › Review article › peer-review

1207 Scopus citations

Microglial microRNAs mediate sex-specific responses to tau pathology

Kodama, L., Guzman, E., Etchegaray, J. I., Li, Y., Sayed, F. A., Zhou, L., Zhou, Y., Zhan, L., Le, D., Udeochu, J. C., Clelland, C. D., Cheng, Z., Yu, G., Li, Q., Kosik, K. S. & Gan, L., Feb 1 2020, In: Nature neuroscience. 23, 2, p. 167-171 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

75 Scopus citations

Micropublication: Incentivizing community curation and placing unpublished data into the public domain

Raciti, D., Yook, K., Harris, T. W., Schedl, T. & Sternberg, P. W., Jan 1 2018, In: Database. 2018, 2018

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

MicroRNA predictors of longevity in caenorhabditis elegans

Pincus, Z., Smith-Vikos, T. & Slack, F. J., Sep 2011, In: PLoS genetics. 7, 9, e1002306.

Research output: Contribution to journal › Article › peer-review

Open Access

157 Scopus citations

MicroRNA profiling reveals marker of motor neuron disease in ALS models

Hoye, M. L., Koval, E. D., Wegener, A. J., Hyman, T. S., Yang, C., O’Brien, D. R., Miller, R. L., Cole, T., Schoch, K. M., Shen, T., Kunikata, T., Richard, J. P., Gutmann, D. H., Maragakis, N. J., Kordasiewicz, H. B., Dougherty, J. D. & Miller, T. M., May 31 2017, In: Journal of Neuroscience. 37, 22, p. 5574-5586 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

63 Scopus citations

MicroRNAs as modulators of longevity and the aging process

Kinser, H. E. & Pincus, Z., Mar 1 2020, In: Human genetics. 139, 3, p. 291-308 18 p.

Research output: Contribution to journal › Review article › peer-review

107 Scopus citations

MicroRNAs both promote and antagonize longevity in C. elegans

De Lencastre, A., Pincus, Z., Zhou, K., Kato, M., Lee, S. S. & Slack, F. J., Dec 21 2010, In: Current Biology. 20, 24, p. 2159-2168 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

246 Scopus citations

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment

Cheng, C. J., Bahal, R., Babar, I. A., Pincus, Z., Barrera, F., Liu, C., Svoronos, A., Braddock, D. T., Glazer, P. M., Engelman, D. M., Saltzman, W. M. & Slack, F. J., Feb 5 2015, In: Nature. 518, 7537, p. 107-110 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

696 Scopus citations

MicroRNAs Induce a Permissive Chromatin Environment that Enables Neuronal Subtype-Specific Reprogramming of Adult Human Fibroblasts

Abernathy, D. G., Kim, W. K., McCoy, M. J., Lake, A. M., Ouwenga, R., Lee, S. W., Xing, X., Li, D., Lee, H. J., Heuckeroth, R. O., Dougherty, J. D., Wang, T. & Yoo, A. S., Sep 7 2017, In: Cell Stem Cell. 21, 3, p. 332-348.e9

Research output: Contribution to journal › Article › peer-review

Open Access

99 Scopus citations

MicroRNAs modulate schwann cell response to nerve injury by reinforcing transcriptional silencing of dedifferentiation-related genes

Viader, A., Chang, L. W., Fahrner, T., Nagarajan, R. & Milbrandt, J., Nov 30 2011, In: Journal of Neuroscience. 31, 48, p. 17358-17369 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

104 Scopus citations

Microsatellite linkage analysis, single-nucleotide polymorphisms, and haplotype associations with ECB21 in the COGA data

Kraja, A. T., Borecki, I. B. & Province, M. A., Dec 30 2005, In: BMC genetics. 6, SUPPL.1, S94.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Midkine induces tumor cell proliferation and binds to a high affinity signaling receptor associated with JAK tyrosine kinases

Ratovitski, E. A., Kotzbauer, P. T., Milbrandt, J., Lowenstein, C. J. & Burrow, C. R., Feb 6 1998, In: Journal of Biological Chemistry. 273, 6, p. 3654-3660 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

Department of Genetics

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