Center for the Investigation of Membrane Excitability Diseases

2010

Sudden cardiac death prediction and prevention: Report from a national heart, lung, and blood institute and heart rhythm society workshop

Fishman, G. I., Chugh, S. S., Dimarco, J. P., Albert, C. M., Anderson, M. E., Bonow, R. O., Buxton, A. E., Chen, P. S., Estes, M., Jouven, X., Kwong, R., Lathrop, D. A., Mascette, A. M., Nerbonne, J. M., O'Rourke, B., Page, R. L., Roden, D. M., Rosenbaum, D. S., Sotoodehnia, N. & Trayanova, N. A. & 1 others, Zheng, Z. J., Nov 30 2010, In: Circulation. 122, 22, p. 2335-2348 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

522 Scopus citations

Targeting of α _νβ ₃-integrins expressed on tumor tissue and neovasculature using fluorescent small molecules and nanoparticles

Akers, W. J., Zhang, Z., Berezin, M., Ye, Y., Agee, A., Guo, K., Fuhrhop, R. W., Wickline, S. A., Lanza, G. M. & Achilefu, S., Jul 2010, In: Nanomedicine. 5, 5, p. 715-726 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

The ATP-sensitive K⁺-channel (K_ATP) controls early left-right patterning in Xenopus and chick embryos

Aw, S., Koster, J. C., Pearson, W., Nichols, C. G., Shi, N. Q., Carneiro, K. & Levin, M., Oct 2010, In: Developmental Biology. 346, 1, p. 39-53 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

The cytoprotective effects of tumor necrosis factor are conveyed through tumor necrosis factor receptor-associated factor 2 in the heart

Burchfield, J. S., Dong, J. W., Sakata, Y., Gao, F., Tzeng, H. P., Topkara, V. K., Entman, M. L., Sivasubramanian, N. & Mann, D. L., Jan 2010, In: Circulation: Heart Failure. 3, 1, p. 157-164 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

The direct molecular effects of fatigue and myosin regulatory light chain phosphorylation on the actomyosin contractile apparatus

Greenberg, M. J., Mealy, T. R., Jones, M., Szczesna-Cordary, D. & Moore, J. R., Apr 2010, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 298, 4, p. R989-R996

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

The effects of BMP6 overexpression on adipose stem cell chondrogenesis: Interactions with dexamethasone and exogenous growth factors

Diekman, B. O., Estes, B. T. & Guilak, F., Jun 1 2010, In: Journal of Biomedical Materials Research - Part A. 93, 3, p. 994-1003 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

50 Scopus citations

The importance of elastin to aortic development in mice

Wagenseil, J. E., Ciliberto, C. H., Knutsen, R. H., Levy, M. A., Kovacs, A. & Mecham, R. P., Aug 2010, In: American Journal of Physiology - Heart and Circulatory Physiology. 299, 2, p. H257-H264

Research output: Contribution to journal › Article › peer-review

Open Access

57 Scopus citations

The Matrix-Binding Domain of Microfibril-Associated Glycoprotein-1 Targets Active Connective Tissue Growth Factor to a Fibroblast-Produced Extracellular Matrix

Weinbaum, J. S., Tranquillo, R. T. & Mecham, R. P., Nov 10 2010, In: Macromolecular Bioscience. 10, 11, p. 1338-1344 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

The molecular basis of frictional loads in the in vitro motility assay with applications to the study of the loaded mechanochemistry of molecular motors

Greenberg, M. J. & Moore, J. R., May 2010, In: Cytoskeleton. 67, 5, p. 273-285 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

65 Scopus citations

The role of presynaptic dynamics in processing of natural spike trains in hippocampal synapses

Kandaswamy, U., Deng, P. Y., Stevens, C. F. & Klyachko, V. A., Nov 24 2010, In: Journal of Neuroscience. 30, 47, p. 15904-15914 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

The SLO3 sperm-specific potassium channel plays a vital role in male fertility

Santi, C. M., Martínez-López, P., de la Vega-Beltrán, J. L., Butler, A., Alisio, A., Darszon, A. & Salkoff, L., Mar 5 2010, In: FEBS Letters. 584, 5, p. 1041-1046 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

198 Scopus citations

The sticky issue of neurosteroids and GABA_A receptors

Chisari, M., Eisenman, L. N., Covey, D. F., Mennerick, S. & Zorumski, C. F., Jul 2010, In: Trends in Neurosciences. 33, 7, p. 299-306 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

85 Scopus citations

Tissue-tissue interactions during morphogenesis of the outflow tract

Rentschler, S., Jain, R. & Epstein, J. A., 2010, In: Pediatric Cardiology. 31, 3, p. 408-413 6 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity

Du, J., Wu, Z., Ren, S., Wei, Y., Gao, M., Randolph, G. J. & Qu, C., Aug 2010, In: Vaccine. 28, 38, p. 6273-6281 9 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Update on the natural history of cavernous malformations and factors predicting aggressive clinical presentation

Washington, C. W., McCoy, K. E. & Zipfel, G. J., Sep 2010, In: Neurosurgical focus. 29, 3, p. 1-7 7 p.

Research output: Contribution to journal › Article › peer-review

107 Scopus citations

Use of an insulating mask for controlling anisotropy in multilayer electrospun scaffolds for tissue engineering

Garrigues, N. W., Little, D., O'Conor, C. J. & Guilak, F., Oct 28 2010, In: Journal of Materials Chemistry. 20, 40, p. 8962-8968 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Use of a wearable automated defibrillator in children compared to young adults

Collins, K. K., Silva, J. N. A., Rhee, E. K. & Schaffer, M. S., Sep 1 2010, In: PACE - Pacing and Clinical Electrophysiology. 33, 9, p. 1119-1124 6 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Vertebrobasilar Flow Evaluation and Risk of Transient Ischaemic Attack and Stroke study (VERiTAS): Rationale and design

Amin-Hanjani, S., Rose-Finnell, L., Richardson, D. J., Ruland, S., Pandey, D., Thulborn, K. R., Liebeskind, D. S., Zipfel, G. J., Elkind, M. S. V., Kramer, J., Silver, F. L., Kasner, S. E., Caplan, L. R., Derdeyn, C. P., Gorelick, P. B. & Charbel, F. T., Dec 2010, In: International Journal of Stroke. 5, 6, p. 499-505 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

Voltage-dependent gating in a "voltage sensor-less" ion channel

Kurata, H. T., Rapedius, M., Kleinman, M. J., Baukrowitz, T. & Nichols, C. G., Feb 2010, In: PLoS biology. 8, 2, e100031.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Welcome from the Society Presidents

Piston, D., Vincenzi, E., Hogue, F. & Beniac, D., Jan 1 2010, In: Microscopy and Microanalysis. 16, S1, 1 p.

Research output: Contribution to journal › Article › peer-review

2009

Acipimox, an inhibitor of lipolysis, attenuates atherogenesis in LDLR-Null mice treated with HIV protease inhibitor ritonavir

Guo, W., Wong, S., Pudney, J., Jasuja, R., Hua, N., Jiang, L., Miller, A., Hruz, P. W., Hamilton, J. A. & Bhasin, S., Dec 2009, In: Arteriosclerosis, thrombosis, and vascular biology. 29, 12, p. 2028-2032 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Acquired copy number alterations in adult acute myeloid leukemia genomes

Walter, M. J., Payton, J. E., Ries, R. E., Shannon, W. D., Deshmukh, H., Zhao, Y., Baty, J., Heath, S., Westervelt, P., Watson, M. A., Tomasson, M. H., Nagarajan, R., O'Gara, B. P., Bloomfield, C. D., Mrózek, K., Selzer, R. R., Richmond, T. A., Kitzman, J., Geoghegan, J. & Eis, P. S. & 9 others, Maupin, R., Fulton, R. S., McLellan, M., Wilson, R. K., Mardis, E. R., Link, D. C., Graubert, T. A., DiPersio, J. F. & Ley, T. J., Aug 4 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 31, p. 12950-12955 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

215 Scopus citations

Activatable molecular systems using homologous near-infrared fluorescent Probes for monitoring enzyme activities in vitro, in pCellulo, and in vivo

Zhang, Z., Fan, J., Cheney, P. P., Berezin, M. Y., Edwards, W. B., Akers, W. J., Shen, D., Liang, K., Culver, J. P. & Achilefu, S., Apr 6 2009, In: Molecular Pharmaceutics. 6, 2, p. 416-427 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

Activation and modulation of concatemeric GABA-A receptors expressed in human embryonic kidney cells

Akk, G., Li, P., Bracamontes, J. & Steinbach, J. H., Jun 2009, In: Molecular pharmacology. 75, 6, p. 1400-1411 12 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Adaptive and maladptive effects of SMAD3 signaling in the adult heart after hemodynamic pressure overloading

Divakaran, V., Adrogue, J., Ishiyama, M., Entman, M. L., Haudek, S., Sivasubramanian, N. & Mann, D. L., Nov 2009, In: Circulation: Heart Failure. 2, 6, p. 633-642 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

101 Scopus citations

Adenylyl cyclases 1 and 8 initiate a presynaptic homeostatic response to ethanol treatment

Conti, A. C., Maas, J. W., Moulder, K. L., Jiang, X., Dave, B. A., Mennerick, S. & Muglia, L. J., May 27 2009, In: PloS one. 4, 5, e5697.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Advanced Heart Failure and Transplant Cardiology: A Subspecialty is Born

Konstam, M. A., Jessup, M., Francis, G. S., Mann, D. L. & Greenberg, B., Mar 2009, In: Journal of cardiac failure. 15, 2, p. 98-100 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Advanced material strategies for tissue engineering scaffolds

Freed, L. E., Engelmayr, G. C., Borenstein, J. T., Moutos, F. T. & Guilak, F., Sep 4 2009, In: Advanced Materials. 21, 32-33, p. 3410-3418 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

192 Scopus citations

A novel role for stat1 in phagosome acidification and natural host resistance to intracellular infection by leishmania majors

Späth, G. F., Schlesinger, P., Schreiber, R. & Beverley, S. M., Apr 2009, In: PLoS pathogens. 5, 4

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Automated lipid identification and quantification by multidimensional mass spectrometry-based shotgun lipidomics

Yang, K., Cheng, H., Gross, R. W. & Han, X., Jun 1 2009, In: Analytical Chemistry. 81, 11, p. 4356-4368 13 p.

Research output: Contribution to journal › Article › peer-review

306 Scopus citations

Biomechanics: Cell research and applications for the next decade

Discher, D., Dong, C., Fredberg, J. J., Guilak, F., Ingber, D., Janmey, P., Kamm, R. D., Schmid-Schönbein, G. W. & Weinbaum, S., May 2009, In: Annals of biomedical engineering. 37, 5, p. 847-859 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

173 Scopus citations

Blast-related brain injury: imaging for clinical and research applications: report of the 2008 st. louis workshop

Benzinger, T. L. S., Brody, D., Cardin, S., Curley, K. C., Mintun, M. A., Mun, S. K., Wong, K. H., Wrathall, J. R., Armstrong, R. C., Bayly, P. V., Bentley, T. B., Chavko, M., Corbetta, M., Culver, J. P., DeWitt, D. S., Faden, A. I., Fiskum, G., Fitzpatrick, S. M., Gennarelli, T. & Ghajar, J. & 36 others, Gullapalli, R. P., Hovda, D., Jost, R. G., Kharasch, E. D., Kharasch, K., Kochanek, P., Lammle, M., Leggieri, M. J., Latour, L. L., Little, D. M., Mac Donald, C. L., Macedonia, C., Marcus, D., McCabe, J. T., McCarron, R. M., Moore, D., Mukherjee, P., Povlishock, J., Pancrazio, J., Petersen, S., Peskind, E. R., Pierce, K. J., Pineda, J. A., Raskind, M., Riedel, C., Ritzel, D., Shimony, J. S., Smith, A. B., Smith, D. H., Smirniotopoulos, J., Song, V. S. K., Sterkel, B. B., Svetlov, S., VandeVord, P. J., Young, A. W. & Zipfel, G., Dec 1 2009, In: Journal of neurotrauma. 26, 12, p. 2127-2144 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

65 Scopus citations

Both primitive and definitive blood cells are derived from Flk-1 ⁺ mesoderm

Lugus, J. J., Park, C., Ma, Y. D. & Choi, K., Jan 15 2009, In: Blood. 113, 3, p. 563-566 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

74 Scopus citations

Bovine and mouse SLO3 K⁺ channels. Evolutionary divergence points to an RCK1 region of critical function

Santi, C. M., Butler, A., Kuhn, J., Wei, A. & Salkoff, L., Aug 7 2009, In: Journal of Biological Chemistry. 284, 32, p. 21589-21598 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Ca2+-independent alterations in diastolic sarcomere length and relaxation kinetics in a mouse model of lipotoxic diabetic cardiomyopathy

Flagg, T. P., Cazorla, O., Remedi, M. S., Haim, T. E., Tones, M. A., Bahinski, A., Numann, R. E., Kovacs, A., Schaffer, J. E., Nichols, C. G. & Nerbonne, J. M., Jan 2 2009, In: Circulation research. 104, 1, p. 95-103 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Scopus citations

Cardiac resynchronization therapy in pediatric congenital heart disease: Insights from noninvasive electrocardiographic imaging

Silva, J. N. A., Ghosh, S., Bowman, T. M., Rhee, E. K., Woodard, P. K. & Rudy, Y., Aug 2009, In: Heart rhythm. 6, 8, p. 1178-1185 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Cellular calcium deficiency plays a role in neuronal death caused by proteasome inhibitors

Wu, S., Hyrc, K. L., Moulder, K. L., Lin, Y., Warmke, T. & Snider, B. J., Jun 2009, In: Journal of Neurochemistry. 109, 5, p. 1225-1236 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Cerebral amyloid angiopathy progressive disruption of the neurovascular unit

Zipfel, G. J., Han, H., Ford, A. L. & Lee, J. M., Mar 2009, In: Stroke. 40, 3 SUPPL. 1, p. S16-S19

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

Cerebral hemodynamics as a predictor of stroke in adult patients with moyamoya disease: a prospective observational study

Zipfel, G. J., Sagar, J., Miller, J. P., Videen, T. O., Grubb, R. L., Dacey, R. G. & Derdeyn, C. P., 2009, In: Neurosurgical focus. 26, 4, p. 1-5 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Chondrogenic differentiation of adipose-derived adult stem cells by a porous scaffold derived from native articular cartilage extracellular matrix

Cheng, N. C., Estes, B. T., Awad, H. A. & Guilak, F., Feb 1 2009, In: Tissue Engineering - Part A. 15, 2, p. 231-241 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

255 Scopus citations

Claudin-16 and claudin-19 interaction is required for their assembly into tight junctions and for renal reabsorption of magnesium

Hou, J., Renigunta, A., Gomes, A. S., Hou, M., Paul, D. L., Waldegger, S. & Goodenough, D. A., Sep 8 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 36, p. 15350-15355 6 p.

Research output: Contribution to journal › Article › peer-review

228 Scopus citations

Closed-channel block of BK potassium channels by bbTBA requires partial activation

Tang, Q. Y., Zeng, X. H. & Lingle, C. J., Nov 2009, In: Journal of General Physiology. 134, 5, p. 409-436 28 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Comparative effects of heterologous TRVP1 and TRPM8 expression in rat hippocampal neurons

Crawford, D. C., Moulder, K. L., Gereau IV, R. W., Story, G. M. & Mennerick, S., 2009, In: PloS one. 4, 12, e8166.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Cranial dural arteriovenous fistulae: Asymptomatic cortical venous drainage portends less aggressive clinical course

Strom, R. G., Botros, J. A., Refai, D., Moran, C. J., Dewittet Cross, I. I. I., Chicoine, M. R., Grubb, R. L., Rich, K. M., Dacey, R. G., Derdeyn, C. P. & Zipfel, G. J., Feb 2009, In: Neurosurgery. 64, 2, p. 241-247 7 p.

Research output: Contribution to journal › Article › peer-review

130 Scopus citations

Defects in osteoblast function but no changes in long-term repopulating potential of hematopoietic stem cells in a mouse chronic inflammatory arthritis model

Ma, Y. D., Park, C., Zhao, H., Oduro, K. A., Tu, X., Long, F., Allen, P. M., Teitelbaum, S. L. & Choi, K., Nov 12 2009, In: Blood. 114, 20, p. 4402-4410 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion

Pound, L. D., Sarkar, S. A., Benninger, R. K. P., Wang, Y., Suwanichkul, A., Shadoan, M. K., Printz, R. L., Oeser, J. K., Lee, C. E., Piston, D. W., McGuinness, O. P., Hutton, J. C., Powell, D. R. & O'Brien, R. M., Aug 1 2009, In: Biochemical Journal. 421, 3, p. 371-376 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

151 Scopus citations

Detergent-activated BAX protein is a monomer

Ivashyna, O., García-Sáez, A. J., Ries, J., Christenson, E. T., Schwille, P. & Schlesinger, P. H., Sep 4 2009, In: Journal of Biological Chemistry. 284, 36, p. 23935-23946 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Developmental and osteoarthritic changes in Col6a1-knockout mice: Biomechanics of type VI collagen in the cartilage pericellular matrix

Alexopoulos, L. G., Youn, I., Bonaldo, P. & Guilak, F., Mar 2009, In: Arthritis and rheumatism. 60, 3, p. 771-779 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

151 Scopus citations

Differential regulation of action potentials by inactivating and noninactivating BK channels in rat adrenal chromaffin cells

Sun, L., Xiong, Y., Zeng, X., Wu, Y., Pan, N., Lingle, C. J., Qu, A. & Ding, J., Oct 7 2009, In: Biophysical Journal. 97, 7, p. 1832-1842 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Differential roles of blocking ions in KirBac1.1 tetramer stability

Wang, S., Alimi, Y., Tong, A., Nichols, C. G. & Enkvetchakul, D., Jan 30 2009, In: Journal of Biological Chemistry. 284, 5, p. 2854-2860 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Center for the Investigation of Membrane Excitability Diseases

Research output

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