Center for Brain Immunology & Glia (BIG)

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Veeraraghavalu, K., Zhang, C., Miller, S., Hefendehl, J. K., Rajapaksha, T. W., Ulrich, J., Jucker, M., Holtzman, D. M., Tanzi, R. E., Vassar, R. & Sisodia, S. S., 2013, In: Science. 340, 6135, p. 924 1 p.

Research output: Contribution to journal › Comment/debate

118 Scopus citations

Comparative analysis of selenocysteine machinery and selenoproteome gene expression in mouse brain identifies neurons as key functional sites of selenium in mammals

Zhang, Y., Zhou, Y., Schweizer, U., Savaskan, N. E., Hua, D., Kipnis, J., Hatfield, D. L. & Gladyshev, V. N., Jan 25 2008, In: Journal of Biological Chemistry. 283, 4, p. 2427-2438 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

158 Scopus citations

Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer’s disease

Dominantly Inherited Alzheimer Network, Dec 2024, In: Nature communications. 15, 1, 9982.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid

Hu, Y., Malone, J. P., Fagan, A. M., Townsend, R. R. & Holtzman, D. M., Dec 2005, In: Molecular and Cellular Proteomics. 4, 12, p. 2000-2005 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

107 Scopus citations

Comparing neoantigen cancer vaccines and immune checkpoint therapy unveils an effective vaccine and anti-TREM2 macrophage-targeting dual therapy

Keshari, S., Shavkunov, A. S., Miao, Q., Saha, A., Minowa, T., Molgora, M., Williams, C. D., Chaib, M., Highsmith, A. M., Pineda, J. E., Alekseev, S., Alspach, E., Hu, K. H., Colonna, M., Pauken, K. E., Chen, K. & Gubin, M. M., Nov 26 2024, In: Cell Reports. 43, 11, 114875.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study

Alzheimer's Biomarker Consortium-Down Syndrome, Dominantly Inherited Alzheimer Network, Boerwinkle, A. H., Gordon, B. A., Wisch, J., Flores, S., Henson, R. L., Butt, O. H., McKay, N., Chen, C. D., Benzinger, T. L. S., Fagan, A. M., Cruchaga, C., Perrin, R. J., Xiong, C., Hassenstab, J., McDade, E., Bateman, R. J., Ances, B. M. & Barthelemy, N. & 8 others, Buckles, V., Day, G., Joseph-Mathurin, N., Holtzman, D., Karch, C., Li, Y., Wang, Q. & Xu, J., Jan 2023, In: The Lancet Neurology. 22, 1, p. 55-65 11 p.

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Comparison of analytical platforms for cerebrospinal fluid measures of β-amyloid 1-42, Total tau, and P-tau₁₈₁ for identifying alzheimer disease amyloid plaque pathology

Fagan, A. M., Shaw, L. M., Xiong, C., Vanderstichele, H., Mintun, M. A., Trojanowski, J. Q., Coart, E., Morris, J. C. & Holtzman, D. M., Sep 2011, In: Archives of neurology. 68, 9, p. 1137-1144 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

159 Scopus citations

Comparison of a single-channel EEG sleep study to polysomnography

Lucey, B. P., Mcleland, J. S., Toedebusch, C. D., Boyd, J., Morris, J. C., Landsness, E. C., Yamada, K. & Holtzman, D. M., Dec 1 2016, In: Journal of Sleep Research. 25, 6, p. 625-635 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

129 Scopus citations

Comparison of cerebrospinal fluid, plasma and neuroimaging biomarker utility in Alzheimer’s disease

Meeker, K. L., Luckett, P. H., Barthélemy, N. R., Hobbs, D. A., Chen, C., Bollinger, J., Ovod, V., Flores, S., Keefe, S., Henson, R. L., Herries, E. M., McDade, E., Hassenstab, J. J., Xiong, C., Cruchaga, C., Benzinger, T. L. S., Holtzman, D. M., Schindler, S. E., Bateman, R. J. & Morris, J. C. & 2 others, Gordon, B. A. & Ances, B. M., 2024, In: Brain Communications. 6, 2

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Comparison of plasma and CSF biomarkers in predicting cognitive decline

Aschenbrenner, A. J., Li, Y., Henson, R. L., Volluz, K., Hassenstab, J., Verghese, P., West, T., Meyer, M. R., Kirmess, K. M., Fagan, A. M., Xiong, C., Holtzman, D., Morris, J. C., Bateman, R. J. & Schindler, S. E., Nov 2022, In: Annals of Clinical and Translational Neurology. 9, 11, p. 1739-1751 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Comparison of single-channel EEG, actigraphy, and sleep diary in cognitively normal and mildly impaired older adults

Chou, C. A., Toedebusch, C. D., Redrick, T., Freund, D., McLeland, J. S., Morris, J. C., Holtzman, D. M. & Lucey, B. P., 2020, In: SLEEP Advances. 1, 1, zpaa006.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study

Alzheimer's Biomarker Consortium–Down Syndrome, Dominantly Inherited Alzheimer Network, Wisch, J. K., McKay, N. S., Boerwinkle, A. H., Kennedy, J., Flores, S., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., Rafii, M. S., O'Bryant, S. E., Price, J. C., Laymon, C. M., Krinsky-McHale, S. J., Lai, F., Rosas, H. D., Hartley, S. L. & Zaman, S. & 152 others, Lott, I. T., Tudorascu, D., Zammit, M., Brickman, A. M., Lee, J. H., Bird, T. D., Cohen, A., Chrem, P., Daniels, A., Chhatwal, J. P., Cruchaga, C., Ibanez, L., Jucker, M., Karch, C. M., Day, G. S., Lee, J. H., Levin, J., Llibre-Guerra, J., Li, Y., Lopera, F., Roh, J. H., Ringman, J. M., Supnet-Bell, C., van Dyck, C. H., Xiong, C., Wang, G., Morris, J. C., McDade, E., Bateman, R. J., Benzinger, T. L. S., Gordon, B. A., Ances, B. M., Aizenstein, H. J., Andrews, H. F., Bell, K., Birn, R. M., Bulova, P., Cheema, A., Chen, K., Clare, I., Clark, L., Cohen, A. D., Constantino, J. N., Doran, E. W., Feingold, E., Foroud, T. M., Hartley, S. L., Hom, C., Honig, L., Ikonomovic, M. D., Johnson, S. C., Jordan, C., Kamboh, M. I., Keator, D., Klunk, W. E., Kofler, J. K., Kreisl, W. C., Krinsky-McHale, S. J., Lao, P., Laymon, C., Lott, I. T., Lupson, V., Mathis, C. A., Minhas, D. S., Nadkarni, N., Pang, D., Petersen, M., Price, J. C., Pulsifer, M., Reiman, E., Rizvi, B., Sabbagh, M. N., Schupf, N., Tudorascu, D. L., Tumuluru, R., Tycko, B., Varadarajan, B., White, D. A., Yassa, M. A., Zhang, F., Bateman, R., Daniels, A., Courtney, L., Llibre-Guerra, J., Xiong, C., Xu, X., Lu, R., Gremminger, E., Perrin, R. J., Franklin, E., Jerome, G., Herries, E., Stauber, J., Baker, B., Minton, M., Goate, A. M., Renton, A. E., Picarello, D. M., Benzinger, T., Gordon, B. A., Hornbeck, R., Hassenstab, J., Smith, J., Stout, S., Aschenbrenner, A. J., Karch, C. M., Marsh, J., Morris, J. C., Holtzman, D. M., Barthelemy, N., Xu, J., Noble, J. M., Berman, S. B., Ikonomovic, S., Nadkarni, N. K., Day, G., Graff-Radford, N. R., Farlow, M., Chhatwal, J. P., Ikeuchi, T., Kasuga, K., Niimi, Y., Huey, E. D., Salloway, S., Schofield, P. R., Brooks, W. S., Bechara, J. A., Martins, R., Fox, N. C., Cash, D. M., Ryan, N. S., Laske, C., Hofmann, A., Kuder-Buletta, E., Graber-Sultan, S., Obermueller, U., Roedenbeck, Y., Vöglein, J., Sanchez-Valle, R., Rosa-Neto, P., Allegri, R. F., Chrem Mendez, P., Surace, E., Vazquez, S., Leon, Y. M., Ramirez, L., Aguillon, D., Levey, A. I., Johnson, E. C. B., Seyfried, N. T., Ringman, J. & Mori, H., May 2024, In: The Lancet Neurology. 23, 5, p. 500-510 11 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation

Barchet, W., Price, J. D., Cella, M., Colonna, M., MacMillan, S. K., Cobb, J. P., Thompson, P. A., Murphy, K. M., Atkinson, J. P. & Kemper, C., Feb 15 2006, In: Blood. 107, 4, p. 1497-1504 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK⁺ CD8⁺ T Cells as Conserved Hallmark of Inflammaging

Mogilenko, D. A., Shpynov, O., Andhey, P. S., Arthur, L., Swain, A., Esaulova, E., Brioschi, S., Shchukina, I., Kerndl, M., Bambouskova, M., Yao, Z., Laha, A., Zaitsev, K., Burdess, S., Gillfilan, S., Stewart, S. A., Colonna, M. & Artyomov, M. N., Jan 12 2021, In: Immunity. 54, 1, p. 99-115.e12

Research output: Contribution to journal › Article › peer-review

Open Access

359 Scopus citations

Conformational plasticity revealed by the cocrystal structure of NKG2D and its class i MHC-like ligand ULBP3

Radaev, S., Rostro, B., Brooks, A. G., Colonna, M. & Sun, P. D., 2001, In: Immunity. 15, 6, p. 1039-1049 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

141 Scopus citations

Continuous positive airway pressure increases CSF flow and glymphatic transport

Ozturk, B., Koundal, S., Al Bizri, E., Chen, X., Gursky, Z., Dai, F., Lim, A., Heerdt, P., Kipnis, J., Tannenbaum, A., Lee, H. & Benveniste, H., 2023, In: JCI Insight. 8, 12, e170270.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice

Han, B. H., Zhou, M. L., Johnson, A. W., Singh, I., Liao, F., Vellimana, A. K., Nelson, J. W., Milner, E., Cirrito, J. R., Basak, J., Yoo, M., Dietrich, H. H., Holtzman, D. M. & Zipfel, G. J., Feb 24 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 8, p. E881-E890

Research output: Contribution to journal › Article › peer-review

Open Access

122 Scopus citations

Controlled autoimmunity in CNS maintenance and repair: Naturally occurring CD4+CD25+ regulatory T-cells at the crossroads of health and disease

Kipnis, J. & Schwartz, M., Aug 2005, In: NeuroMolecular Medicine. 7, 3, p. 197-206 10 p.

Research output: Contribution to journal › Review article › peer-review

40 Scopus citations

Controlled cortical impact traumatic brain injury in 3xTg-AD mice causes acute intra-axonal amyloid-β accumulation and independently accelerates the development of tau abnormalities

Tran, H. T., LaFerla, F. M., Holtzman, D. M. & Brody, D. L., Jun 29 2011, In: Journal of Neuroscience. 31, 26, p. 9513-9525 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

232 Scopus citations

Converting to adapt: Gut microbiota affect T cell plasticity in the intestinal lining

Colonna, M. & Cervantes-Barragan, L., Jun 24 2016, In: Science. 352, 6293, p. 1515-1516 2 p.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Corpora amylacea are associated with tau burden and cognitive status in Alzheimer’s disease

Wander, C. M., Tsujimoto, T. H. M., Ervin, J. F., Wang, C., Maranto, S. M., Bhat, V., Dallmeier, J. D., Wang, S. H. J., Lin, F. C., Scott, W. K., Holtzman, D. M. & Cohen, T. J., Dec 2022, In: Acta Neuropathologica Communications. 10, 1, 110.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Correction: Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism (Molecular Neurodegeneration, (2018), 13, 1, (57), 10.1186/s13024-018-0286-0)

Ma, Q., Zhao, Z., Sagare, A. P., Wu, Y., Wang, M., Owens, N. C., Verghese, P. B., Herz, J., Holtzman, D. M. & Zlokovic, B. V., Dec 2022, In: Molecular neurodegeneration. 17, 1, 71.

Research output: Contribution to journal › Comment/debate

Open Access

5 Scopus citations

Correction: AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy [The Journal of Experimental Medicine, 214, 5 (2017) (1227-1238)] DOI:10.1084/jem.20162125

Ising, C., Gallardo, G., Leyns, C. E. G., Wong, C. H., Jiang, H., Stewart, F., Koscal, L. J., Roh, J., Robinson, G. O., Serrano, J. R. & Holtzman, D. M., Jul 1 2017, In: Journal of Experimental Medicine. 214, 7, p. 2163 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

3 Scopus citations

Correction to: Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism (Molecular Neurodegeneration, (2018), 13, 1, (57), 10.1186/s13024-018-0286-0)

Ma, Q., Zhao, Z., Sagare, A. P., Wu, Y., Wang, M., Owens, N. C., Verghese, P. B., Herz, J., Holtzman, D. M. & Zlokovic, B. V., Dec 2024, In: Molecular neurodegeneration. 19, 1, 27.

Research output: Contribution to journal › Comment/debate

Open Access

1 Scopus citations

Correction to: Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy (Nature, (2023), 615, 7953, (668-677), 10.1038/s41586-023-05788-0)

Chen, X., Firulyova, M., Manis, M., Herz, J., Smirnov, I., Aladyeva, E., Wang, C., Bao, X., Finn, M. B., Hu, H., Shchukina, I., Kim, M. W., Yuede, C. M., Kipnis, J., Artyomov, M. N., Ulrich, J. D. & Holtzman, D. M., Oct 31 2024, In: Nature. 634, 8036, p. E15

Research output: Contribution to journal › Comment/debate

Open Access

1 Scopus citations

Correction to: Hypoxia enhances ILC3 responses through HIF-1α-dependent mechanism (Mucosal Immunology, (2021), 14, 4, (828-841), 10.1038/s41385-020-00371-6)

Fachi, J. L., Pral, L. P., dos Santos, J. A. C., Codo, A. C., de Oliveira, S., Felipe, J. S., Zambom, F. F. F., Câmara, N. O. S., Vieira, P. M. M. M., Colonna, M. & Vinolo, M. A. R., Jul 2021, In: Mucosal Immunology. 14, 4, p. 973 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

Correction to: Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner (Molecular Neurodegeneration, (2024), 19, 1, (18), 10.1186/s13024-023-00700-w)

Bosch, M. E., Dodiya, H. B., Michalkiewicz, J., Lee, C., Shaik, S. M., Weigle, I. Q., Zhang, C., Osborn, J., Nambiar, A., Patel, P., Parhizkar, S., Zhang, X., Laury, M. L., Mondal, P., Gomm, A., Schipma, M. J., Mallah, D., Butovsky, O., Chang, E. B. & Tanzi, R. E. & 3 others, Gilbert, J. A., Holtzman, D. M. & Sisodia, S. S., Dec 2024, In: Molecular neurodegeneration. 19, 1, 70.

Research output: Contribution to journal › Comment/debate

Open Access

1 Scopus citations

Correction to: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE (Nature Neuroscience, (2019), 22, 2, (191-204), 10.1038/s41593-018-0296-9)

Parhizkar, S., Arzberger, T., Brendel, M., Kleinberger, G., Deussing, M., Focke, C., Nuscher, B., Xiong, M., Ghasemigharagoz, A., Katzmarski, N., Krasemann, S., Lichtenthaler, S. F., Müller, S. A., Colombo, A., Monasor, L. S., Tahirovic, S., Herms, J., Willem, M., Pettkus, N. & Butovsky, O. & 9 others, Bartenstein, P., Edbauer, D., Rominger, A., Ertürk, A., Grathwohl, S. A., Neher, J. J., Holtzman, D. M., Meyer-Luehmann, M. & Haass, C., Sep 2024, In: Nature neuroscience. 27, 9, p. 1858-1859 2 p.

Research output: Contribution to journal › Comment/debate

Open Access

Correction to Potential role of orexin and sleep modulation in the pathogenesis of alzheimer's disease [The Journal of Experimental Medicine, 211, 13, (2014), 2487-2496]

Roh, J. H., Jiang, H., Finn, M. B., Stewart, F. R., Mahan, T. E., Cirrito, J. R., Heda, A., Joy Snider, B., Li, M., Yanagisawa, M., de Lecea, L. & Holtzman, D. M., Jan 12 2015, In: Journal of Experimental Medicine. 212, 1, p. 121 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

3 Scopus citations

Correction to Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's disease [The Journal of Experimental Medicine, 211, 13, (2014), 2487-2496]

Roh, J. H., Jiang, H., Finn, M. B., Stewart, F. R., Mahan, T. E., Cirrito, J. R., Heda, A., Joy Snider, B., Li, M., Yanagisawa, M., de Lecea, L. & Holtzman, D. M., 2014, In: Journal of Experimental Medicine. 211, 13, p. 2487-2496 10 p.

Research output: Contribution to journal › Comment/debate

Open Access

190 Scopus citations

Corrigendum: Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

Saito, F., Hirayasu, K., Satoh, T., Wang, C. W., Lusingu, J., Arimori, T., Shida, K., Palacpac, N. M. Q., Itagaki, S., Iwanaga, S., Takashima, E., Tsuboi, T., Kohyama, M., Suenaga, T., Colonna, M., Takagi, J., Lavstsen, T., Horii, T. & Arase, H., Feb 22 2018, In: Nature. 554, 7693, p. 554 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

2 Scopus citations

Corrigendum to “Triggering receptor expressed on myeloid cells-2 is involved in prion-induced microglial activation but does not contribute to prion pathogenesis in mouse brains” [Neurobiol. Aging 36 (2015) 1994–2003, (S0197458015001505), (10.1016/j.neurobiolaging.2015.02.019)]

Zhu, C., Herrmann, U. S., Li, B., Abakumova, I., Moos, R., Schwarz, P., Rushing, E. J., Colonna, M. & Aguzzi, A., Feb 2025, In: Neurobiology of Aging. 146, p. 77-78 2 p.

Research output: Contribution to journal › Comment/debate

Cortical Binding of Pittsburgh Compound B, an Endophenotype for Genetic Studies of Alzheimer's Disease

Hinrichs, A. L., Mintun, M. A., Head, D., Fagan, A. M., Holtzman, D. M., Morris, J. C. & Goate, A. M., Mar 15 2010, In: Biological Psychiatry. 67, 6, p. 581-583 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Costimulation through NKG2D enhances murine CD8⁺ CTL function: Similarities and differences between NKG2D and CD28 costimulation

Markiewicz, M. A., Carayannopoulos, L. N., Naidenko, O. V., Matsui, K., Burack, W. R., Wise, E. L., Fremont, D. H., Allen, P. M., Yokoyama, W. M., Colonna, M. & Shaw, A. S., Sep 1 2005, In: Journal of Immunology. 175, 5, p. 2825-2833 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

105 Scopus citations

CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion

Sanjuan, M. A., Rao, N., Lai, K. T. A., Gu, Y., Sun, S., Fuchs, A., Fung-Leung, W. P., Colonna, M. & Karlsson, L., Mar 2006, In: Journal of Cell Biology. 172, 7, p. 1057-1068 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

114 Scopus citations

Cranioencephalic functional lymphoid units in glioblastoma

Dobersalske, C., Rauschenbach, L., Hua, Y., Berliner, C., Steinbach, A., Grüneboom, A., Kokkaliaris, K. D., Heiland, D. H., Berger, P., Langer, S., Tan, C. L., Stenzel, M., Landolsi, S., Weber, F., Darkwah Oppong, M., Werner, R. A., Gull, H., Schröder, T., Linsenmann, T. & Buck, A. K. & 16 others, Gunzer, M., Stuschke, M., Keyvani, K., Forsting, M., Glas, M., Kipnis, J., Steindler, D. A., Reinhardt, H. C., Green, E. W., Platten, M., Tasdogan, A., Herrmann, K., Rambow, F., Cima, I., Sure, U. & Scheffler, B., Oct 2024, In: Nature medicine. 30, 10, p. 2947-2956 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Critical issues for successful immunotherapy in Alzheimer's disease: Development of biomarkers and methods for early detection and intervention

Tarawneh, R. & Holtzman, D. M., 2009, In: CNS and Neurological Disorders - Drug Targets. 8, 2, p. 144-159 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis

Terwel, D., Steffensen, K. R., Verghese, P. B., Kummer, M. P., Gustafsson, J. Å., Holtzman, D. M. & Heneka, M. T., May 11 2011, In: Journal of Neuroscience. 31, 19, p. 7049-7059 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

163 Scopus citations

Critical role of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of inflammation-driven dermal fibrosis in a mouse model of systemic sclerosis

Avouac, J., Elhai, M., Tomcik, M., Ruiz, B., Friese, M., Piedavent, M., Colonna, M., Bernhardt, G., Kahan, A., Chiocchia, G., Distler, J. H. W. & Allanore, Y., Jun 2013, In: Annals of the Rheumatic Diseases. 72, 6, p. 1089-1098 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Crosspresentation: Plasmacytoid Dendritic Cells Are in the Business

Colonna, M. & Cella, M., Sep 21 2007, In: Immunity. 27, 3, p. 419-421 3 p.

Research output: Contribution to journal › Short survey › peer-review

Open Access

29 Scopus citations

CRTAM controls residency of gut CD4⁺CD8⁺ T cells in the steady state and maintenance of gut CD4⁺ Th17 during parasitic infection

Cortez, V. S., Cervantes-Barragan, L., Song, C., Gilfillan, S., McDonald, K. G., Tussiwand, R., Edelson, B. T., Murakami, Y., Murphy, K. M., Newberry, R. D., Sibley, L. D. & Colonna, M., Apr 2014, In: Journal of Experimental Medicine. 211, 4, p. 623-633 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

CRTAM protects against intestinal dysbiosis during pathogenic parasitic infection by enabling Th17 maturation

Cervantes-Barragan, L., Cortez, V. S., Wang, Q., McDonald, K. G., Chai, J. N., Luccia, B. D., Gilfillan, S., Hsieh, C. S., Newberry, R. D., David Sibley, L. & Colonna, M., 2019, In: Frontiers in immunology. 10, JUL, 1423.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Crystal structure of human natural cytotoxicity receptor NKp30 and identification of its ligand binding site

Joyce, M. G., Paul, T., Zhuravleva, M. A., Jaw, J., Colonna, M. & Sun, P. D., Apr 12 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 15, p. 6223-6228 6 p.

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Crystal Structure of the Human Myeloid Cell Activating Receptor TREM-1

Radaev, S., Kattah, M., Rostro, B., Colonna, M. & Sun, P. D., Dec 2003, In: Structure. 11, 12, p. 1527-1535 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

Crystal Structure of the Human Natural Killer (NK) Cell Activating Receptor NKp46 Reveals Structural Relationship to Other Leukocyte Receptor Complex Immunoreceptors

Foster, C. E., Colonna, M. & Sun, P. D., Nov 14 2003, In: Journal of Biological Chemistry. 278, 46, p. 46081-46086 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

60 Scopus citations

CSF biomarkers for Alzheimer's disease: Current utility and potential future use

Holtzman, D. M., Dec 2011, In: Neurobiology of Aging. 32, SUPPL. 1, p. S4

Research output: Contribution to journal › Article › peer-review

99 Scopus citations

CSF biomarkers for secondary prevention trials: why markers of amyloid deposition and neurodegeneration are both important.

Holtzman, D. M., Jun 2012, In: Archives of neurology. 69, 6, p. 691-692 2 p.

Research output: Contribution to journal › Editorial

3 Scopus citations

CSF biomarkers of alzheimer disease

Roe, C. M., Fagan, A. M., Grant, E. A., Holtzman, D. M. & Morris, J. C., Dec 3 2013, In: Neurology. 81, 23, p. 2028-2031 4 p.

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Open Access

22 Scopus citations

CSF biomarkers of Alzheimer disease in HIV-associated neurologic disease

Clifford, D. B., Fagan, A. M., Holtzman, D. M., Morris, J. C., Teshome, M., Shah, A. R. & Kauwe, J. S. K., Dec 2009, In: Neurology. 73, 23, p. 1982-1987 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

149 Scopus citations

CSF biomarkers of immune activation and Alzheimer’s disease for predicting cognitive impairment risk in the elderly

Shue, F., White, L. J., Hendrix, R. D., Ulrich, J., Henson, R. L., Knight, W., Martens, Y. A., Wang, N., Roy, B., Starling, S. C., Ren, Y., Xiong, C., Asmann, Y. W., Syrjanen, J. A., Vassilaki, M., Mielke, M. M., Timsina, J., Sung, Y. J., Cruchaga, C. & Holtzman, D. M. & 4 others, Bu, G., Petersen, R. C., Heckman, M. G. & Kanekiyo, T., Apr 2024, In: Science Advances. 10, 14, eadk3674.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Center for Brain Immunology & Glia (BIG)

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